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Background: Numerous studies have evaluated the effect that mindfulness-based interventions (MBIs) have on multiple health outcomes. For its part, stress is a natural response to environmental disturbances and within the associated metabolic responses, alterations in cortisol levels and their measurement in different tissues are a way to determine the stress state of an individual. Therefore, it has been proposed that MBIs can modify cortisol levels. Methods and results: The objective of this systematic review was to analyze and summarize the different studies that have evaluated the effect of MBIs on cortisol levels. The following databases were consulted: MEDLINE, AMED, CINAHL, Web of Science, Science Direct, PsycINFO, SocINDEX, PubMed, the Cochrane Library and Scopus. The search terms “mindfulness”, “mindfulness-based interventions” and “cortisol” were used (and the search was limited to studies from January 1990 to May 2024). In order to reduce selection bias, each article was scrutinized using the JBI Critical Appraisal Checklist independently by two authors. We included those studies with specified intervention groups with at least one control group and excluded duplicate studies or those in which the intervention or control group was not adequately specified. Significant changes in cortisol following MBIs were found in 25 studies, while 10 found no changes. The small sample size, lack of randomization, blinding, and probable confounding and interaction variables stand out in these studies. Conclusion: MBIs have biological plausibility as a means of explaining a positive effect on cortisol levels; however, the weakness of the studies and the absence of robust designs makes it difficult to establish a causal association between both variables. Registration number: INPLASY2024110017.

Background: Numerous studies have evaluated the effect that mindfulness-based interventions (MBIs) have on multiple health outcomes. For its part, stress is a natural response to environmental disturbances and within the associated metabolic responses, alterations in cortisol levels and their measurement in different tissues are a way to determine the stress state of an individual. Therefore, it has been proposed that MBIs can modify cortisol levels. Methods and results: The objective of this systematic review was to analyze and summarize the different studies that have evaluated the effect of MBIs on cortisol levels. The following databases were consulted: MEDLINE, AMED, CINAHL, Web of Science, Science Direct, PsycINFO, SocINDEX, PubMed, the Cochrane Library and Scopus. The search terms "mindfulness", "mindfulness-based interventions" and "cortisol" were used (and the search was limited to studies from January 1990 to May 2024). In order to reduce selection bias, each article was scrutinized using the JBI Critical Appraisal Checklist independently by two authors. We included those studies with specified intervention groups with at least one control group and excluded duplicate studies or those in which the intervention or control group was not adequately specified. Significant changes in cortisol following MBIs were found in 25 studies, while 10 found no changes. The small sample size, lack of randomization, blinding, and probable confounding and interaction variables stand out in these studies. Conclusion: MBIs have biological plausibility as a means of explaining a positive effect on cortisol levels; however, the weakness of the studies and the absence of robust designs makes it difficult to establish a causal association between both variables. Registration number: INPLASY2024110017. [ABSTRACT FROM AUTHOR]

Liver iron overload is the histological hallmark of hereditary hemochromatosis and transfusional hemosiderosis, and can also occur in chronic hepatopathies. Iron overload can result in liver damage, with the eventual development of cirrhosis, liver failure, and hepatocellular carcinoma. Assessment of liver iron levels is necessary for detection and quantitative staging of iron overload and monitoring of iron-reducing treatments. This article discusses the need for noninvasive assessment of liver iron and reviews qualitative and quantitative methods with a particular emphasis on magnetic resonance imaging (MRI). Specific MRI methods for liver iron quantification include signal intensity ratio as well as R2 and R2∗ relaxometry techniques. Methods that are in clinical use, as well as their limitations, are described. Remaining challenges, unsolved problems, and emerging techniques to provide improved characterization of liver iron deposition are discussed.

In this exposition we go over the Talavera Pottery from the XVI to the XX centuries, analyzing the main facts which marked its developement, and providing some of the keys neccesary to understand the importance and the influence its production had in other centers. We emphasize on items related to the XVI and XVII centuries, origin and decadence, giving some data about its chronology and series, based on the latest discoveries. In relation to the XVIII, XIX and XX centuries, we only expose the changes wich took place and the consequences they brought to the potteries of Talavera.En esta ponencia se hace un recorrido por la historia de la “Cerámica de Talavera” de los siglos XVI al XX, analizando los principales hechos que marcan su desarrollo y aportando algunas de las claves necesarias para comprender su importancia y la influencia que van a ejercer sus producciones en otros centros. Se hace especial hincapié en las cuestiones relativas a los siglos XVI y XVII, origen y decadencia, aportando algunos datos nuevos sobre su cronología y sus series, en base a los últimos descubrimientos. En relación a los siglos XVIII, XIX y XX, solamente se exponen los cambios que se producen y las consecuencias que para las lozas talaveranas acarrearon.

A historic approach of the origins of the Ceramic Museum “Ruiz de Luna” in Talavera de la Reina, the harmony of its space and its expositive design. The importance of its stored property when studying the productions of Talavera and Puente in particular, and all the Spanish pottery in general. Other items are also taken into consideration, especially those related to the Pemanent Collection, to the stored property opened to visitors, to the stored property of investigation and the growth of its dimension with its extension in the “disperse Museum”.Recorrido histórico de los orígenes del Museo de Cerámica de Talavera “Ruiz de Luna”, la articulación de sus espacios y su diseño expositivo. La importancia de sus fondos a la hora de estudiar las producciones de Talavera - Puente en particular y para las lozas españolas en general. También se abordan otras cuestiones relativas a la Colección Permanente, los fondos visitables, los fondos de investigación y el crecimiento de su dimensión con su prolongación en el “Museo disperso”.