Search

Your search keyword '"Hernández-Alonso, Pablo"' showing total 204 results
Start Over Author "Hernández-Alonso, Pablo"
204 results on '"Hernández-Alonso, Pablo"'

2. Plasma lipidome and risk of atrial fibrillation: results from the PREDIMED trial

Author

Toledo, Estefania, Wittenbecher, Clemens, Razquin, Cristina, Ruiz-Canela, Miguel, Clish, Clary B., Liang, Liming, Alonso, Alvaro, Hernández-Alonso, Pablo, Becerra-Tomás, Nerea, Arós-Borau, Fernando, Corella, Dolores, Ros, Emilio, Estruch, Ramón, García-Rodríguez, Antonio, Fitó, Montserrat, Lapetra, José, Fiol, Miquel, Alonso-Gomez, Ángel M., Serra-Majem, Luis, Deik, Amy, Salas-Salvadó, Jordi, Hu, Frank B., and Martínez-González, Miguel A.

Published
2023
Full Text
View/download PDF

3. Acilcarnitinas en plasma y riesgo de insuficiencia cardiaca y fibrilación auricular: el estudio Prevención con dieta mediterránea

Author

Ruiz-Canela, Miguel, Guasch-Ferré, Marta, Razquin, Cristina, Toledo, Estefanía, Hernández-Alonso, Pablo, Clish, Clary B., Li, Jun, Wittenbecher, Clemens, Dennis, Courtney, Alonso-Gómez, Ángel, Almanza-Aguilera, Enrique, Liang, Liming, Corella, Dolores, Gómez-Gracia, Enrique, Estruch, Ramón, Fiol, Miguel, Lapetra, José, Serra-Majem, Lluis, Ros, Emilio, Arós, Fernando, Salas-Salvadó, Jordi, Hu, Frank B., and Martínez-González, Miguel Ángel

Published
2022
Full Text
View/download PDF

4. Dietary vitamin D intake and colorectal cancer risk: a longitudinal approach within the PREDIMED study

Author

Hernández-Alonso, Pablo, Canudas, Silvia, Boughanem, Hatim, Toledo, Estefanía, Sorlí, Jose V., Estruch, Ramón, Castañer, Olga, Lapetra, José, Alonso-Gómez, Angel M., Gutiérrez-Bedmar, Mario, Fiol, Miquel, Serra-Majem, Lluis, Pintó, Xavier, Ros, Emilio, Fernandez-Lazaro, Cesar I., Ramirez-Sabio, Judith B., Fitó, Montse, Portu-Zapirain, Joseba, Macias-González, Manuel, Babio, Nancy, and Salas-Salvadó, Jordi

Published
2021
Full Text
View/download PDF

5. Metabolomics of the tryptophan–kynurenine degradation pathway and risk of atrial fibrillation and heart failure: potential modification effect of Mediterranean diet

Author

Razquin, Cristina, Ruiz-Canela, Miguel, Toledo, Estefania, Hernández-Alonso, Pablo, Clish, Clary B, Guasch-Ferré, Marta, Li, Jun, Wittenbecher, Clemens, Dennis, Courtney, Alonso-Gómez, Angel, Fitó, Montse, Liang, Liming, Corella, Dolores, Gómez-Gracia, Enrique, Estruch, Ramon, Fiol, Miquel, Lapetra, Jose, Serra-Majem, Lluis, Ros, Emilio, Aros, Fernando, Salas-Salvadó, Jordi, Hu, Frank B, and Martínez-González, Miguel A

Published
2021
Full Text
View/download PDF

6. Relationship between olive oil consumption and ankle-brachial pressure index in a population at high cardiovascular risk

Author

Sánchez-Quesada, Cristina, Toledo, Estefanía, González-Mata, Guadalupe, Ramos-Ballesta, Maria Isabel, Peis, José Ignacio, Martínez-González, Miguel Ángel, Salas-Salvadó, Jordi, Corella, Dolores, Fitó, Montserrat, Romaguera, Dora, Vioque, Jesús, Alonso-Gómez, Ángel M., Wärnberg, Julia, Martínez, J. Alfredo, Serra-Majem, Luís, Estruch, Ramon, Tinahones, Francisco J., Lapetra, José, Pintó, Xavier, Tur, Josep A., Garcia-Rios, Antonio, Cano-Ibáñez, Naomi, Matía-Martín, Pilar, Daimiel, Lidia, Sánchez-Rodríguez, Rubén, Vidal, Josep, Vázquez, Clotilde, Ros, Emilio, Hernández-Alonso, Pablo, Barragan, Rocío, Muñoz-Martínez, Julia, López, Meritxell, González-Palacios, Sandra, Vaquero-Luna, Jessica, Crespo-Oliva, Edelys, Zulet, M. Angeles, Díaz-González, Vanessa, Casas, Rosa, Fernandez-Garcia, José Carlos, Santos-Lozano, José Manuel, Galera, Ana, Ripoll-Vera, Tomás, Buil-Cosiales, Pilar, Canudas, Silvia, Martinez-Lacruz, Raul, Pérez-Vega, Karla-Alejandra, Rios, Ángel, Lloret-Macián, Rosario, Moreno-Rodriguez, Anai, Ruiz-Canela, Miguel, Babio, Nancy, Zomeño Fajardo, Maria Dolores, and Gaforio, José J.

Published
2020
Full Text
View/download PDF

8. Machinery labor fronts. A contribution to management of mechanization in sugarcane production bases.

Author

Andrés García-Pérez, Julio, Manuel Hernández-Alonso, Pablo, Luis Velarde-Sosa, Ernesto, Pausa Bello, Evelio, and Socarrás-Laza, Dámaso

Subjects
*SUGARCANE harvesting, *MECHANIZATION, *TECHNICAL assistance, *OBSOLESCENCE, *SUGAR
Abstract

Mechanization management in sugarcane production bases today faces difficulties such as the obsolescence of machinery with an average age for tractors higher than 30 years. The high dependence on external services, the duality of the harvesting system where external services are received from modern combines. and a park of old machines is operated by sugar cane production bases such as cooperatives, fragmented into teams of very low productivity, which affects the organization of logistics, technical assistance and the use of transportation. This paper theoretically demonstrates the advantages in machinery management achieved by forming labor fronts with the equipment of two or more bases, to jointly harvest the sugarcane areas. Likewise, the advantages of using the fronts as operational centers for other tasks that can be fulfilled with high quality in unison with the harvest or immediately after it is executed. The implementation of the fronts in the 2021 - 2022 harvest is described, resulting greater productivity for the harvesters grouped in the new system and demonstrating the possibility of achieving greater sugar yield. [ABSTRACT FROM AUTHOR]

Published
2024

9. Diagnóstico del estado de la mecanización cañera. Visión del productor.

Author

Andrés García-Pérez, Julio, Luis Velarde-Sosa, Ernesto, Manuel Hernández-Alonso, Pablo, Pausa Bello, Evelio, and Socarrás-Laza, Dámaso

Subjects
CORPORATE directors, FARM mechanization, AGRICULTURAL productivity, COOPERATIVE agriculture, MECHANIZATION
Abstract

Copyright of Ingeniería Agrícola is the property of Instituto de Investigaciones de Ingenieria Agricola and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024

11. Nuts

Author

Galiè, Serena, primary, Bulló, Mònica, additional, Atzeni, Alessandro, additional, Hernández-Alonso, Pablo, additional, Muralidharan, Jananee, additional, and Salas-Salvadó, Jordi, additional

Published
2020
Full Text
View/download PDF

18. Plasma acylcarnitines and risk of incident heart failure and atrial fibrillation: the Prevención con dieta mediterránea study

Author

Ruiz-Canela, Miguel, primary, Guasch-Ferré, Marta, additional, Razquin, Cristina, additional, Toledo, Estefanía, additional, Hernández-Alonso, Pablo, additional, Clish, Clary B., additional, Li, Jun, additional, Wittenbecher, Clemens, additional, Dennis, Courtney, additional, Alonso-Gómez, Ángel, additional, Almanza-Aguilera, Enrique, additional, Liang, Liming, additional, Corella, Dolores, additional, Gómez-Gracia, Enrique, additional, Estruch, Ramón, additional, Fiol, Miguel, additional, Lapetra, José, additional, Serra-Majem, Lluis, additional, Ros, Emilio, additional, Arós, Fernando, additional, Salas-Salvadó, Jordi, additional, Hu, Frank B., additional, and Martínez-González, Miguel Ángel, additional

Published
2022
Full Text
View/download PDF

20. Circulating vitamin D levels and colorectal cancer risk: A meta-analysis and systematic review of case-control and prospective cohort studies.

Author

Hernández-Alonso, Pablo, Boughanem, Hatim, Canudas, Silvia, Becerra-Tomás, Nerea, Fernández de la Puente, María, Babio, Nancy, Macias-Gonzalez, Manuel, and Salas-Salvadó, Jordi

Subjects
*FIXED effects model, *VITAMIN D, *COLORECTAL cancer, *LONGITUDINAL method, *DISEASE risk factors, *RANDOM effects model
Abstract

The associations between circulating vitamin D concentrations and total and site-specific colorectal cancer (CRC) incidence have been examined in several epidemiological studies with overall inconclusive findings. The aim of this systematic review and meta-analysis of both case-control and prospective cohort studies was to evaluate the association between CRC and circulating levels of vitamin D. The main exposure and outcome were circulating total 25(OH)D and CRC, respectively, in the overall population (i.e., all subjects). Two reviewers, working independently, screened all the literature available to identify studies that met the inclusion criteria (e.g., case-control or prospective cohort studies, published in English, and excluding non-original papers). Data were pooled by the generic inverse variance method using a random or fixed effect model, as approriate. Heterogeneity was identified using the Cochran's Q-test and quantified by the I2 statistic. Results were stratified by study design, sex, and metabolite of vitamin D. Sensitivity and subgroup analyses were also performed. A total of 28 original studies were included for the quantitative meta-analysis. Meta-analyses comparing the highest vs lowest categories, showed a 39% lower risk between levels of total 25(OH)D and CRC risk (OR (95% CI): 0.61 (0.52; 0.71); 11 studies) in case-control studies; whereas a 20% reduced CRC risk in prospective cohort studies (HR (95% CI): 0.80 (0.66; 0.97); 6 studies). Results in women mirrored main results, whereas results in men were non-significant in both analyses. Our findings support an inverse association between circulating vitamin D levels and CRC risk. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

22. Physical activity and metabolic syndrome severity among older adults at cardiovascular risk: 1-Year trends

Author

Gallardo-Alfaro, Laura, primary, Bibiloni, Maria del Mar, additional, Bouzas, Cristina, additional, Mascaró, Catalina M., additional, Martínez-González, Miguel Ángel, additional, Salas-Salvadó, Jordi, additional, Corella, Dolores, additional, Schröder, Helmut, additional, Martínez, J. Alfredo, additional, Alonso-Gómez, Ángel M., additional, Wärnberg, Julia, additional, Vioque, Jesús, additional, Romaguera, Dora, additional, Lopez-Miranda, José, additional, Estruch, Ramon, additional, Tinahones, Francisco J., additional, Lapetra, José, additional, Serra-Majem, Luís, additional, Bueno-Cavanillas, Aurora, additional, Micó, Rafael M., additional, Pintó, Xavier, additional, Gaforio, José J., additional, Ortíz-Ramos, María, additional, Altés-Boronat, Andreu, additional, Luca, Bogdana L., additional, Daimiel, Lidia, additional, Ros, Emilio, additional, Sayon-Orea, Carmen, additional, Becerra-Tomás, Nerea, additional, Gimenez-Alba, Ignacio Manuel, additional, Castañer, Olga, additional, Abete, Itziar, additional, Tojal-Sierra, Lucas, additional, Pérez-López, Jéssica, additional, Torres-Collado, Laura, additional, Colom, Antoni, additional, Garcia-Rios, Antonio, additional, Castro-Barquero, Sara, additional, Bernal, Rosa, additional, Santos-Lozano, José Manuel, additional, Fernandez-Lazaro, Cesar I., additional, Hernández-Alonso, Pablo, additional, Saiz, Carmen, additional, Zomeño, Maria Dolors, additional, Zulet, Maria Angeles, additional, Belló-Mora, Maria C., additional, Basterra-Gortari, F. Javier, additional, Canudas, Silvia, additional, Goday, Albert, additional, and Tur, Josep A., additional

Published
2021
Full Text
View/download PDF

26. Dairy consumption, plasma metabolites, and risk of type 2 diabetes

Author

Drouin-Chartier, Jean-Philippe, primary, Hernández-Alonso, Pablo, additional, Guasch-Ferré, Marta, additional, Ruiz-Canela, Miguel, additional, Li, Jun, additional, Wittenbecher, Clemens, additional, Razquin, Cristina, additional, Toledo, Estefanía, additional, Dennis, Courtney, additional, Corella, Dolores, additional, Estruch, Ramon, additional, Fitó, Montserrat, additional, Eliassen, A Heather, additional, Tobias, Deirdre K, additional, Ascherio, Alberto, additional, Mucci, Lorelei A, additional, Rexrode, Kathryn M, additional, Karlson, Elizabeth W, additional, Costenbader, Karen H, additional, Fuchs, Charles S, additional, Liang, Liming, additional, Clish, Clary B, additional, Martínez-González, Miguel A, additional, Salas-Salvadó, Jordi, additional, and Hu, Frank B, additional

Published
2021
Full Text
View/download PDF

27. Urea Cycle Metabolites and Atrial Fibrillation or Heart Failure Risk: Two Case-Control Studies in the PREDIMED Trial

Author

Goni, Leticia, primary, Razquin, Cristina, additional, Toledo, Estefania, additional, Guasch-Ferre, Marta, additional, Clish, Clary B., additional, Hernández-Alonso, Pablo, additional, Li, Jun, additional, Liang, Liming, additional, Wittenbecher, Clemens, additional, Dennis, Courtney, additional, Alonso-Gomez, Angel, additional, Fitó, Montse, additional, Corella, Dolores, additional, Gomez-Gracia, Enrique, additional, Estruch, Ramon, additional, Fiol, Miquel, additional, Lapreta, Jose, additional, Serra-Majem, Lluis, additional, Ros, Emilio, additional, Aros, Fernando, additional, Salas-Salvado, Jordi, additional, Hu, Frank, additional, Martinez-Gonzalez, Miguel Ángel, additional, and Ruiz-Canela, Miguel, additional

Published
2021
Full Text
View/download PDF

28. Glycolysis Metabolites and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Trial

Author

Becerra-Tomás, Nerea, primary, Ruiz-Canela, Miguel, additional, Hernández-Alonso, Pablo, additional, Bulló, Mònica, additional, Li, Jun, additional, Guasch-Ferré, Marta, additional, Toledo, Estefanía, additional, Clish, Clary B., additional, Estruch, Ramon, additional, Ros, Emilio, additional, Fitó, Montserrat, additional, Lee, Chih-Hao, additional, Pierce, Kerry, additional, Arós, Fernando, additional, Serra-Majem, Lluís, additional, Liang, Liming, additional, Razquin, Cristina, additional, Gómez-Gracia, Enrique, additional, Martínez-González, Miguel A., additional, Hu, Frank B., additional, Corella, Dolores, additional, and Salas-Salvadó, Jordi, additional

Published
2021
Full Text
View/download PDF

29. Longitudinal changes in adherence to the portfolio and DASH dietary patterns and cardiometabolic risk factors in the PREDIMED-Plus study

Author

Glenn, Andrea J., primary, Hernández-Alonso, Pablo, additional, Kendall, Cyril W.C., additional, Martínez-González, Miguel Ángel, additional, Corella, Dolores, additional, Fitó, Montserrat, additional, Martínez, J.Alfredo, additional, Alonso-Gómez, Ángel M., additional, Wärnberg, Julia, additional, Vioque, Jesús, additional, Romaguera, Dora, additional, López-Miranda, José, additional, Estruch, Ramon, additional, Tinahones, Francisco J., additional, Lapetra, José, additional, Serra-Majem, J. Luís, additional, Bueno-Cavanillas, Aurora, additional, Tur, Josep A., additional, Celada, Sofia Reguero, additional, Pintó, Xavier, additional, Delgado-Rodríguez, Miguel, additional, Matía-Martín, Pilar, additional, Vidal, Josep, additional, Mas-Fontao, Sebastian, additional, Daimiel, Lidia, additional, Ros, Emilio, additional, Jenkins, David J.A., additional, Toledo, Estefania, additional, Sorlí, José V., additional, Castañer, Olga, additional, Abete, Itziar, additional, Rodriguez, Anai Moreno, additional, Barceló, Olga Fernández, additional, Oncina-Canovas, Alejandro, additional, Konieczna, Jadwiga, additional, Garcia-Rios, Antonio, additional, Casas, Rosa, additional, Gómez-Pérez, Ana Maria, additional, Santos-Lozano, José Manuel, additional, Vazquez-Ruiz, Zenaida, additional, Portolés, Olga, additional, Schröder, Helmut, additional, Zulet, Maria A., additional, Eguaras, Sonia, additional, Lete, Itziar Salaverria, additional, Zomeño, María Dolores, additional, Sievenpiper, John L., additional, and Salas-Salvadó, Jordi, additional

Published
2021
Full Text
View/download PDF

30. Longitudinal changes in adherence to the portfolio and DASH dietary patterns and cardiometabolic risk factors in the PREDIMED-Plus study

Author

Glenn, Andrea J., Hernández-Alonso, Pablo, Kendall, Cyril W.C., Martínez-González, Miguel Ángel, Corella, Dolores, Fitó, Montserrat, Santos Lozano, José Manuel, Salas-Salvadó, Jordi, and Universidad de Sevilla. Departamento de Medicina

Subjects
PORTFOLIO diet, PREDIMED-Plus trial, DASH diet, Dietary pattern, Metabolic syndrome, Cardiometabolic risk
Abstract

Background & aims The Portfolio and Dietary Approaches to Stop Hypertension (DASH) diets have been shown to lower cardiometabolic risk factors in randomized controlled trials (RCTs). However, the Portfolio diet has only been assessed in RCTs of hyperlipidemic patients. Therefore, to assess the Portfolio diet in a population with metabolic syndrome (MetS), we conducted a longitudinal analysis of one-year data of changes in the Portfolio and DASH diet scores and their association with cardiometabolic risk factors in Prevención con Dieta Mediterránea (PREDIMED)-Plus trial. Methods PREDIMED-Plus is an ongoing clinical trial (Trial registration: ISRCTN89898) conducted in Spain that includes 6874 older participants (mean age 65 y, 48% women) with overweight/obesity fulfilling at least three criteria for MetS. Data for this analysis were collected at baseline, six months and one year. Adherence to the Portfolio and DASH diet scores were derived from a validated 143-item food frequency questionnaire. We used linear mixed models to examine the associations of 1-SD increase and quartile changes in the diet scores with concomitant changes in cardiometabolic risk factors. Results After adjusting for several potential confounders, a 1-SD increase in the Portfolio diet score was significantly associated with lower HbA1c (β [95% CI]: −0.02% [−0.02, −0.01], P < 0.001), fasting glucose (−0.47 mg/dL [−0.83, −0.11], P = 0.01), triglycerides (−1.29 mg/dL [−2.31, −0.28], P = 0.01), waist circumference (WC) (−0.51 cm [−0.59, −0.43], P < 0.001), and body mass index (BMI) (−0.17 kg/m2 [−0.19, −0.15], P < 0.001). A 1-SD increase in the DASH diet score was significantly associated with lower HbA1c (−0.03% [−0.04, −0.02], P < 0.001), glucose (−0.84 mg/dL [−1.18, −0.51], P < 0.001), triglycerides (−3.38 mg/dL [−4.37, −2.38], P < 0.001), non-HDL-cholesterol (−0.47 mg/dL [−0.91, −0.04], P = 0.03), WC (−0.69 cm [−0.76, −0.60 cm], P < 0.001), BMI (−0.25 kg/m2 [−0.28, −0.26 kg/m2], P < 0.001), systolic blood pressure (−0.57 mmHg [−0.81, −0.32 mmHg], P < 0.001), diastolic blood pressure (−0.15 mmHg [−0.29, −0.01 mmHg], P = 0.03), and with higher HDL-cholesterol (0.21 mg/dL [0.09, 0.34 mg/dL, P = 0.001]). Similar associations were seen when both diet scores were assessed as quartiles, comparing extreme categories of adherence. Conclusions Among older adults at high cardiovascular risk with MetS, greater adherence to the Portfolio and DASH diets showed significant favourable prospective associations with several clinically relevant cardiometabolic risk factors. Both diets are likely beneficial for cardiometabolic risk reduction.

Published
2021

31. Los efectos económicos de la crisis de 2020 en España, Alemania, Francia e Italia

Author

Hernández Alonso, Pablo, Universidad de Valladolid. Facultad de Ciencias Económicas y Empresariales, Hernández Alonso, Pablo, and Universidad de Valladolid. Facultad de Ciencias Económicas y Empresariales

Abstract

La pandemia del COVID-19 ha tenido unas de las mayores implicaciones negativas tanto sanitarias como económicas de los últimos 100 años. En este trabajo vamos a poder conocer la evolución sanitaria y económica desde que empezó la pandemia hasta mediados de 2021 en Alemania, España, Francia, Italia y la Unión Europea, e intentar analizar y explicar sus causas y sus efectos, así como las distintas medidas que se han llevado a cabo para mitigar las consecuencias negativas. A nivel sanitario, la pandemia nos ha dejado millones de contagios y de muertes, y a su vez las distintas restricciones llevadas a cabo para controlar el avance del virus se han trasladado al ámbito económico. A nivel económico hubo una fuerte caída inicial de la actividad que deterioro los datos de las principales variables macroeconómicas y posteriormente se produjo una progresiva recuperación gracias al papel de la política monetaria y fiscal y de la relajación de las medidas restrictivas, que tuvieron que volver a endurecerse en algunos momentos por el empeoramiento de la situación sanitaria, por lo que se ralentizo esa recuperación. A mediados de 2021 aún no se han recuperado los principales datos económicos previos a la pandemia, Grado en Economía

Published
2021

33. Walnut Consumption, Plasma Metabolomics, and Risk of Type 2 Diabetes and Cardiovascular Disease

Author

Guasch-Ferré, Marta, primary, Hernández-Alonso, Pablo, additional, Drouin-Chartier, Jean-Philippe, additional, Ruiz-Canela, Miguel, additional, Razquin, Cristina, additional, Toledo, Estefanía, additional, Li, Jun, additional, Dennis, Courtney, additional, Wittenbecher, Clemens, additional, Corella, Dolores, additional, Estruch, Ramon, additional, Fitó, Montserrat, additional, Ros, Emilio, additional, Babio, Nancy, additional, Bhupathiraju, Shilpa N, additional, Clish, Clary B, additional, Liang, Liming, additional, Martínez-González, Miguel A, additional, Hu, Frank B, additional, and Salas-Salvadó, Jordi, additional

Published
2021
Full Text
View/download PDF

35. Additional file 2 of Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer

Author

Boughanem, Hatim, Cabrera-Mulero, Amanda, Hernández-Alonso, Pablo, Clemente-Postigo, Mercedes, Casanueva, Felipe F., Tinahones, Francisco José, Morcillo, Sonsoles, Crujeiras, Ana B., and Macias-Gonzalez, Manuel

Abstract

Additional file 2: Figure S2. Representation of methylation status of selected genes under the 30th percentile of vitamin D. a) Methylation status of genes in tumoral tissue. b) Methylation status in visceral adipose tissue.

Published
2020
Full Text
View/download PDF

36. Additional file 1 of Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer

Author

Boughanem, Hatim, Cabrera-Mulero, Amanda, Hernández-Alonso, Pablo, Clemente-Postigo, Mercedes, Casanueva, Felipe F., Tinahones, Francisco José, Morcillo, Sonsoles, Crujeiras, Ana B., and Macias-Gonzalez, Manuel

Abstract

Additional file 1: Figure S1. Promoter overview of the selected genes, generated by UCSC genome Browser (https://genome.ucsc.edu). The sequence analyzed is highlighted in light blue of SFRP-2 (a), TIAM1 (b), ZNF397OS (c), ZNF543 (d), C/EBPα (e), PPAR-γ (f), PGC-1α (g), NF-κB (h), TNF-α (i) and VDR (j).

Published
2020
Full Text
View/download PDF

37. Additional file 6 of Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer

Author

Boughanem, Hatim, Cabrera-Mulero, Amanda, Hernández-Alonso, Pablo, Clemente-Postigo, Mercedes, Casanueva, Felipe F., Tinahones, Francisco José, Morcillo, Sonsoles, Crujeiras, Ana B., and Macias-Gonzalez, Manuel

Subjects
carbohydrates (lipids), parasitic diseases, food and beverages, digestive system diseases
Abstract

Additional file 6: Table S3. General data, clinical and biochemical variables of control and CRC patients.

Published
2020
Full Text
View/download PDF

38. Additional file 3 of Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer

Author

Boughanem, Hatim, Cabrera-Mulero, Amanda, Hernández-Alonso, Pablo, Clemente-Postigo, Mercedes, Casanueva, Felipe F., Tinahones, Francisco José, Morcillo, Sonsoles, Crujeiras, Ana B., and Macias-Gonzalez, Manuel

Subjects
neoplasms, digestive system diseases
Abstract

Additional file 3: Figure S3. The effect of 25-OH vitamin D in the SFRP-2 promoter methylation in HCT116 cell line. SFRP-2 promoter methylation in HCT116 after treatment with 25-OH-Vitamin D during 2, 6, 12, 24, 48 and 72 hours under 10 and 100 nM. The results are given as the methylation average mean and standard deviation. Abbreviations: SFRP2: Secreted frizzled-related protein type 2; HCT116: Homo sapiens colon colorectal carcinoma.

Published
2020
Full Text
View/download PDF

39. Additional file 5 of Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer

Author

Boughanem, Hatim, Cabrera-Mulero, Amanda, Hernández-Alonso, Pablo, Clemente-Postigo, Mercedes, Casanueva, Felipe F., Tinahones, Francisco José, Morcillo, Sonsoles, Crujeiras, Ana B., and Macias-Gonzalez, Manuel

Abstract

Additional file 5: Table S2. Data of CpG analyzed and primer sequences of selected promoter

Published
2020
Full Text
View/download PDF

40. High Plasma Glutamate and a Low Glutamine-to-Glutamate Ratio Are Associated with Increased Risk of Heart Failure but Not Atrial Fibrillation in the Prevención con Dieta Mediterránea (PREDIMED) Study

Author

National Institutes of Health (US), Instituto de Salud Carlos III, Ministerio de Economía y Competitividad (España), European Commission, Centro Nacional de Investigaciones Cardiovasculares (España), Centro de Investigación Biomédica en Red Cáncer (España), Generalitat Valenciana, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), American Diabetes Association, Papandreou, Christopher, Hernández-Alonso, Pablo, Bulló, Mònica, Ruiz-Canela, Miguel, Li, Jun, Guasch‐Ferré, Marta, Toledo, Estefania, Clish, Clary B., Corella, Dolores, Estruch, Ramón, Cofán, Montserrat, Fitó, Montserrat, Razquin, Cristina, Arós, Fernando, Fiol, Miquel, Santos-Lozano, J. M., Serra-Majem, Lluis, Liang, Liming, Martínez-González, José, Hu, Frank B., Salas-Salvadó, Jordi, National Institutes of Health (US), Instituto de Salud Carlos III, Ministerio de Economía y Competitividad (España), European Commission, Centro Nacional de Investigaciones Cardiovasculares (España), Centro de Investigación Biomédica en Red Cáncer (España), Generalitat Valenciana, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), American Diabetes Association, Papandreou, Christopher, Hernández-Alonso, Pablo, Bulló, Mònica, Ruiz-Canela, Miguel, Li, Jun, Guasch‐Ferré, Marta, Toledo, Estefania, Clish, Clary B., Corella, Dolores, Estruch, Ramón, Cofán, Montserrat, Fitó, Montserrat, Razquin, Cristina, Arós, Fernando, Fiol, Miquel, Santos-Lozano, J. M., Serra-Majem, Lluis, Liang, Liming, Martínez-González, José, Hu, Frank B., and Salas-Salvadó, Jordi

Abstract

[Background] Although the association between glutamate and glutamine in relation to cardiometabolic disorders has been evaluated, the role of these metabolites in the development of atrial fibrillation (AF) and heart failure (HF) remains unknown., [Objectives] We examined associations of glutamate, glutamine, and the glutamine-to-glutamate ratio with AF and HF incidence in a Mediterranean population at high cardiovascular disease (CVD) risk., [Methods] The present study used 2 nested case-control studies within the PREDIMED (Prevención con Dieta Mediterránea) study. During ∼10 y of follow‐up, there were 509 AF incident cases matched to 618 controls and 326 HF incident cases matched to 426 controls. Plasma concentrations of glutamate and glutamine were semiquantitatively profiled with LC–tandem MS. ORs were estimated with multivariable conditional logistic regression models. [Results] In fully adjusted models, per 1-SD increment, glutamate was associated with a 29% (95% CI: 1.08, 1.54) increased risk of HF and glutamine‐to‐glutamate ratio with a 20% (95% CI: 0.67, 0.94) decreased risk. Glutamine-to-glutamate ratio was also inversely associated with HF risk (OR per 1-SD increment: 0.80; 95% CI: 0.67, 0.94) when comparing extreme quartiles. Higher glutamate concentrations were associated with a worse cardiometabolic risk profile, whereas a higher glutamine-to-glutamate ratio was associated with a better cardiometabolic risk profile. No associations between the concentrations of these metabolites and AF were observed., [Conclusions] Our findings suggest that high plasma glutamate concentrations possibly resulting from alterations in the glutamate-glutamine cycle may contribute to the development of HF in Mediterranean individuals at high CVD risk.

Published
2020

41. Association between the 2018 WCRF/AICR and the Low-Risk Lifestyle Scores with Colorectal Cancer Risk in the Predimed Study

Author

Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (España), Instituto de Salud Carlos III, European Commission, Centro Nacional de Investigaciones Cardiovasculares (España), Ministerio de Ciencia e Innovación (España), Fundación Mapfre, Junta de Andalucía, Generalitat Valenciana, Generalitat de Catalunya, Nafarroako Gobernua, Fundación Patrimonio Comunal Olivarero, Hojiblanca, Institución Catalana de Investigación y Estudios Avanzados, California Walnut Commission, Borges, Morella Nuts, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Ministerio de Educación, Cultura y Deporte (España), Barrubés, Laura, Babio, Nancy, Hernández-Alonso, Pablo, Toledo, Estefania, Ramírez Sabio, Judith B., Estruch, Ramón, Ros, Emilio, Fitó, Montserrat, Alonso-Gómez, Ángel M., Fiol, Miquel, Lapetra, José, Serra-Majem, Lluis, Pintó, Xavier, Ruiz-Canela, Miguel, Corella, Dolores, Macías-González, Manuel, Salas-Salvadó, Jordi, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (España), Instituto de Salud Carlos III, European Commission, Centro Nacional de Investigaciones Cardiovasculares (España), Ministerio de Ciencia e Innovación (España), Fundación Mapfre, Junta de Andalucía, Generalitat Valenciana, Generalitat de Catalunya, Nafarroako Gobernua, Fundación Patrimonio Comunal Olivarero, Hojiblanca, Institución Catalana de Investigación y Estudios Avanzados, California Walnut Commission, Borges, Morella Nuts, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Ministerio de Educación, Cultura y Deporte (España), Barrubés, Laura, Babio, Nancy, Hernández-Alonso, Pablo, Toledo, Estefania, Ramírez Sabio, Judith B., Estruch, Ramón, Ros, Emilio, Fitó, Montserrat, Alonso-Gómez, Ángel M., Fiol, Miquel, Lapetra, José, Serra-Majem, Lluis, Pintó, Xavier, Ruiz-Canela, Miguel, Corella, Dolores, Macías-González, Manuel, and Salas-Salvadó, Jordi

Abstract

Limited longitudinal studies have been conducted to evaluate colorectal cancer (CRC) incidence based on the updated 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) recommendations or other global lifestyle indices, and none in aged populations at high cardiovascular risk. We aimed to assess the association between CRC incidence and adherence to two emerging lifestyles indices (2018 WCRF/AICR score and another low-risk lifestyle (LRL) score comprising smoking status, alcohol consumption, physical activity, diet, and body mass index) in the Spanish PREvencion con DIeta MEDiterranea (PREDIMED) cohort. We studied 7216 elderly men and women at high cardiovascular risk. The 2018 WCRF/AICR and LRL scores were calculated. Multivariable Cox proportional regression models were fitted to estimate the HRs (hazard ratios) and 95% confidence intervals (CIs) for incident CRC events. During a median interquartile range (IQR) follow-up of 6.0 (4.4–7.3) years, 97 CRC events were considered. A significant linear association was observed between each 1-point increment in the WCRF/AICR score (score range from 0 to 7) and CRC risk (HR (95% CI) = 0.79 (0.63–0.99)). Similarly, each 1-point increment in the LRL score (score range from 0 to 5) was associated with a 22% reduction in CRC risk (0.78 (0.64–0.96)). Adhering to emergent lifestyle scores might substantially reduce CRC incidence in elderly individuals. Further longitudinal studies, which take different lifestyle indexes into account, are warranted in the future.

Published
2020

42. Relationship between olive oil consumption and ankle-brachial pressure index in a population at high cardiovascular risk

Author

Instituto de Salud Carlos III, Sánchez-Quesada, Cristina, Toledo, Estefanía, González-Mata, Guadalupe, Ramos-Ballesta, Maria Isabel, Peis, José Ignacio, Martínez-González, Miguel Ángel, Salas-Salvadó, Jordi, Corella, Dolores, Fitó, Montserrat, Romaguera, Dora, Vioque, Jesús, Alonso-Gómez, Ángel M., Wärnberg, Julia, Martínez, J. Alfredo, Serra-Majem, Luís, Estruch, Ramón, Tinahones, Francisco J., Lapetra, José, Pintó, Xavier, Tur, Josep A., Garcia-Rios, Antonio, Cano-Ibáñez, Naomi, Matía-Martín, Pilar, Daimiel, Lidia, Sánchez-Rodríguez, Rubén, Vidal, Josep, Vázquez, Clotilde, Ros, Emilio, Hernández-Alonso, Pablo, Barragán, Rocío, Muñoz-Martínez, Julia, López, Meritxell, González-Palacios, Sandra, Vaquero-Luna, Jessica, Crespo-Oliva, Edelys, Zulet, M. Ángeles, Díaz-González, Vanessa, Casas, Rosa, Fernandez-Garcia, José Carlos, Santos-Lozano, José Manuel, Galera, Ana, Ripoll-Vera, Tomás, Buil-Cosiales, Pilar, Canudas, Silvia, Martínez-Lacruz, Raúl, Pérez-Vega, Karla-Alejandra, Ríos, Ángel, Lloret-Macián, Rosario, Moreno-Rodríguez, Anai, Ruiz-Canela, Miguel, Babio, Nancy, Zomeño Fajardo, Maria Dolores, Gaforio, José Juan, Instituto de Salud Carlos III, Sánchez-Quesada, Cristina, Toledo, Estefanía, González-Mata, Guadalupe, Ramos-Ballesta, Maria Isabel, Peis, José Ignacio, Martínez-González, Miguel Ángel, Salas-Salvadó, Jordi, Corella, Dolores, Fitó, Montserrat, Romaguera, Dora, Vioque, Jesús, Alonso-Gómez, Ángel M., Wärnberg, Julia, Martínez, J. Alfredo, Serra-Majem, Luís, Estruch, Ramón, Tinahones, Francisco J., Lapetra, José, Pintó, Xavier, Tur, Josep A., Garcia-Rios, Antonio, Cano-Ibáñez, Naomi, Matía-Martín, Pilar, Daimiel, Lidia, Sánchez-Rodríguez, Rubén, Vidal, Josep, Vázquez, Clotilde, Ros, Emilio, Hernández-Alonso, Pablo, Barragán, Rocío, Muñoz-Martínez, Julia, López, Meritxell, González-Palacios, Sandra, Vaquero-Luna, Jessica, Crespo-Oliva, Edelys, Zulet, M. Ángeles, Díaz-González, Vanessa, Casas, Rosa, Fernandez-Garcia, José Carlos, Santos-Lozano, José Manuel, Galera, Ana, Ripoll-Vera, Tomás, Buil-Cosiales, Pilar, Canudas, Silvia, Martínez-Lacruz, Raúl, Pérez-Vega, Karla-Alejandra, Ríos, Ángel, Lloret-Macián, Rosario, Moreno-Rodríguez, Anai, Ruiz-Canela, Miguel, Babio, Nancy, Zomeño Fajardo, Maria Dolores, and Gaforio, José Juan

Abstract

[Background and aims]: The aim of this study was to ascertain the association between the consumption of different categories of edible olive oils (virgin olive oils and olive oil) and olive pomace oil and ankle-brachial pressure index (ABI) in participants in the PREDIMED-Plus study, a trial of lifestyle modification for weight and cardiovascular event reduction in individuals with overweight/obesity harboring the metabolic syndrome., [Methods]: We performed a cross-sectional analysis of the PREDIMED-Plus trial. Consumption of any category of olive oil and olive pomace oil was assessed through a validated food-frequency questionnaire. Multivariable linear regression models were fitted to assess associations between olive oil consumption and ABI. Additionally, ABI ≤1 was considered as the outcome in logistic models with different categories of olive oil and olive pomace oil as exposure., [Results]: Among 4330 participants, the highest quintile of total olive oil consumption (sum of all categories of olive oil and olive pomace oil) was associated with higher mean values of ABI (beta coefficient: 0.014, 95% confidence interval [CI]: 0.002, 0.027) (p for trend = 0.010). Logistic models comparing the consumption of different categories of olive oils, olive pomace oil and ABI ≤1 values revealed an inverse association between virgin olive oils consumption and the likelihood of a low ABI (odds ratio [OR] 0.73, 95% CI [0.56, 0.97]), while consumption of olive pomace oil was positively associated with a low ABI (OR 1.22 95% CI [1.00, 1.48])., [Conclusions]: In a Mediterranean population at high cardiovascular risk, total olive oil consumption was associated with a higher mean ABI. These results suggest that olive oil consumption may be beneficial for peripheral artery disease prevention, but longitudinal studies are needed.

Published
2020

43. Assessment of price and nutritional quality of gluten-free products versus their analogues with gluten through the algorithm of the nutri-score front-of-package labeling system

Author

De las Heras-Delgado, Sara, primary, Alías-Guerrero, Adoración de las Nieves, additional, Cendra-Duarte, Esther, additional, Salas-Salvadó, Jordi, additional, Vilchez, Elisenda, additional, Roger, Esther, additional, Hernández-Alonso, Pablo, additional, and Babio, Nancy, additional

Published
2021
Full Text
View/download PDF

44. Plasma Metabolomic Profiles of Glycemic Index, Glycemic Load, and Carbohydrate Quality Index in the PREDIMED Study

Author

Bulló, Mònica, primary, Papandreou, Christopher, additional, Ruiz-Canela, Miguel, additional, Guasch-Ferré, Marta, additional, Li, Jun, additional, Hernández-Alonso, Pablo, additional, Toledo, Estefania, additional, Liang, Liming, additional, Razquin, Cristina, additional, Corella, Dolores, additional, Estruch, Ramon, additional, Ros, Emilio, additional, Fitó, Montserrat, additional, Arós, Fernando, additional, Fiol, Miquel, additional, Serra-Majem, Lluís, additional, Clish, Clary B, additional, Becerra-Tomás, Nerea, additional, Martínez-González, Miguel A, additional, Hu, Frank B, additional, and Salas-Salvadó, Jordi, additional

Published
2021
Full Text
View/download PDF

45. Metabolic Syndrome Features and Excess Weight Were Inversely Associated with Nut Consumption after 1-Year Follow-Up in the PREDIMED-Plus Study

Author

Julibert, Alicia, primary, del Mar Bibiloni, Maria, additional, Gallardo-Alfaro, Laura, additional, Abbate, Manuela, additional, Martínez-González, Miguel Á, additional, Salas-Salvadó, Jordi, additional, Corella, Dolores, additional, Fitó, Montse, additional, Martínez, J Alfredo, additional, Alonso-Gómez, Ángel M, additional, Wärnberg, Julia, additional, Vioque, Jesús, additional, Romaguera, Dora, additional, Lopez-Miranda, José, additional, Estruch, Ramon, additional, Tinahones, Francisco J, additional, Lapetra, José, additional, Serra-Majem, Lluís, additional, Cano-Ibañez, Naomi, additional, Martín-Sánchez, Vicente, additional, Pintó, Xavier, additional, Gaforio, José J, additional, Matía-Martín, Pilar, additional, Vidal, Josep, additional, Vázquez, Clotilde, additional, Daimiel, Lidia, additional, Ros, Emilio, additional, Sayon-Orea, Carmen, additional, Becerra-Tomás, Nerea, additional, Gimenez-Alba, Ignacio M, additional, Castañer, Olga, additional, Abete, Itziar, additional, Tojal-Sierra, Lucas, additional, Pérez-López, Jéssica, additional, Notario-Barandiaran, Leyre, additional, Colom, Antoni, additional, Garcia-Rios, Antonio, additional, Castro-Barquero, Sara, additional, Bernal, Rosa, additional, Santos-Lozano, José M, additional, Fernández-Lázaro, Cesar I, additional, Hernández-Alonso, Pablo, additional, Saiz, Carmen, additional, Zomeño, Maria D, additional, Zulet, Maria A, additional, Belló-Mora, Maria C, additional, Basterra-Gortari, Javier, additional, Canudas, Silvia, additional, Goday, Albert, additional, and Tur, Josep A, additional

Published
2020
Full Text
View/download PDF

46. Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study

Author

Papandreou, Christopher, primary, Bulló, Mònica, additional, Hernández-Alonso, Pablo, additional, Ruiz-Canela, Miguel, additional, Li, Jun, additional, Guasch-Ferré, Marta, additional, Toledo, Estefanía, additional, Clish, Clary, additional, Corella, Dolores, additional, Estruch, Ramon, additional, Ros, Emilio, additional, Fitó, Montserrat, additional, Alonso-Gómez, Angel, additional, Fiol, Miquel, additional, Santos-Lozano, José M, additional, Serra-Majem, Lluís, additional, Liang, Liming, additional, Martínez-González, Miguel A, additional, Hu, Frank B, additional, and Salas-Salvadó, Jordi, additional

Published
2020
Full Text
View/download PDF

47. High Plasma Glutamate and a Low Glutamine-to-Glutamate Ratio Are Associated with Increased Risk of Heart Failure but Not Atrial Fibrillation in the Prevención con Dieta Mediterránea (PREDIMED) Study

Author

Papandreou, Christopher, primary, Hernández-Alonso, Pablo, additional, Bulló, Mònica, additional, Ruiz-Canela, Miguel, additional, Li, Jun, additional, Guasch-Ferré, Marta, additional, Toledo, EstefanÍa, additional, Clish, Clary, additional, Corella, Dolores, additional, Estruch, Ramon, additional, Cofán, Montserrat, additional, Fitó, Montserrat, additional, Razquin, Cristina, additional, Arós, Fernando, additional, Fiol, Miquel, additional, Santos-Lozano, José M, additional, Serra-Majem, LluÍs, additional, Liang, Liming, additional, MartÍnez-González, Miguel A, additional, Hu, Frank B, additional, and Salas-Salvadó, Jordi, additional

Published
2020
Full Text
View/download PDF

48. Dietary Quality Changes According to the Preceding Maximum Weight: A Longitudinal Analysis in the PREDIMED-Plus Randomized Trial

Author

Bouzas, Cristina, primary, Bibiloni, Maria del Mar, additional, Garcia, Silvia, additional, Mateos, David, additional, Martínez-González, Miguel Ángel, additional, Salas-Salvadó, Jordi, additional, Corella, Dolores, additional, Schröder, Helmut, additional, Martínez, J. Alfredo, additional, Alonso-Gómez, Ángel M., additional, Wärnberg, Julia, additional, Vioque, Jesús, additional, Romaguera, Dora, additional, Lopez-Miranda, José, additional, Estruch, Ramon, additional, Tinahones, Francisco J., additional, Lapetra, José, additional, Serra-Majem, Luís, additional, Bueno-Cavanillas, Aurora, additional, Micó-Pérez, Rafael M., additional, Pintó, Xavier, additional, Delgado-Rodríguez, Miguel, additional, Ortíz-Ramos, María, additional, Altés-Boronat, Andreu, additional, Luca, Bogdana L., additional, Daimiel, Lidia, additional, Ros, Emilio, additional, Sayon-Orea, Carmen, additional, Becerra-Tomás, Nerea, additional, Gimenez-Alba, Ignacio Manuel, additional, Castañer, Olga, additional, Abete, Itziar, additional, Tojal-Sierra, Lucas, additional, Pérez-López, Jéssica, additional, Bernabé-Casanova, Andrea, additional, Martin-Padillo, Marian, additional, Garcia-Rios, Antonio, additional, Castro-Barquero, Sara, additional, Fernández-García, José Carlos, additional, Santos-Lozano, José Manuel, additional, Fernandez-Lazaro, Cesar I., additional, Hernández-Alonso, Pablo, additional, Saiz, Carmen, additional, Zomeño, Maria Dolors, additional, Zulet, Maria Angeles, additional, Belló-Mora, Maria C., additional, Basterra-Gortari, F. Javier, additional, Canudas, Silvia, additional, Goday, Albert, additional, and Tur, Josep A., additional

Published
2020
Full Text
View/download PDF

49. Plasma Metabolomics Profiles are Associated with the Amount and Source of Protein Intake: A Metabolomics Approach within the PREDIMED Study

Author

Hernández‐Alonso, Pablo, primary, Becerra‐Tomás, Nerea, additional, Papandreou, Christopher, additional, Bulló, Mònica, additional, Guasch‐Ferré, Marta, additional, Toledo, Estefanía, additional, Ruiz‐Canela, Miguel, additional, Clish, Clary B., additional, Corella, Dolores, additional, Dennis, Courtney, additional, Deik, Amy, additional, Wang, Dong D., additional, Razquin, Cristina, additional, Drouin‐Chartier, Jean‐Philippe, additional, Estruch, Ramon, additional, Ros, Emilio, additional, Fitó, Montserrat, additional, Arós, Fernando, additional, Fiol, Miquel, additional, Serra‐Majem, Lluís, additional, Liang, Liming, additional, Martínez‐González, Miguel A, additional, Hu, Frank B, additional, and Salas‐Salvadó, Jordi, additional

Published
2020
Full Text
View/download PDF

50. Association between the 2018 WCRF/AICR and the Low-Risk Lifestyle Scores with Colorectal Cancer Risk in the Predimed Study

Author

Barrubés, Laura, primary, Babio, Nancy, additional, Hernández-Alonso, Pablo, additional, Toledo, Estefania, additional, Ramírez Sabio, Judith B., additional, Estruch, Ramón, additional, Ros, Emilio, additional, Fitó, Montserrat, additional, Alonso-Gómez, Angel M, additional, Fiol, Miquel, additional, Lapetra, Jose, additional, Serra-Majem, Lluís, additional, Pintó, Xavier, additional, Ruiz-Canela, Miguel, additional, Corella, Dolores, additional, Castañer, Olga, additional, Macías-González, Manuel, additional, and Salas-Salvadó, Jordi, additional

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results