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2. Green Foaming of Biologically Extracted Chitin Hydrogels Using Supercritical Carbon Dioxide for Scaffolding of Human Osteoblasts.

Author

Quintana-Quirino, Mariana, Hernández-Rangel, Adriana, Silva-Bermudez, Phaedra, García-López, Julieta, Domínguez-Hernández, Víctor Manuel, Araujo Monsalvo, Victor Manuel, Gimeno, Miquel, and Shirai, Keiko

Subjects
*CHITIN, *SUPERCRITICAL carbon dioxide, *POROUS materials, *SUBCOOLED liquids, *OSTEOBLASTS, *HYDROGELS, *POLYSACCHARIDES
Abstract

Chitin is a structural polysaccharide abundant in the biosphere. Chitin possesses a highly ordered crystalline structure that makes its processing a challenge. In this study, chitin hydrogels and methanogels, prepared by dissolution in calcium chloride/methanol, were subjected to supercritical carbon dioxide (scCO2) to produce porous materials for use as scaffolds for osteoblasts. The control of the morphology, porosity, and physicochemical properties of the produced materials was performed according to the operational conditions, as well as the co-solvent addition. The dissolution of CO2 in methanol co-solvent improved the sorption of the compressed fluid into the hydrogel, rendering highly porous chitin scaffolds. The chitin crystallinity index significantly decreased after processing the hydrogel in supercritical conditions, with a significant effect on its swelling capacity. The use of scCO2 with methanol co-solvent resulted in chitin scaffolds with characteristics adequate to the adhesion and proliferation of osteoblasts. [ABSTRACT FROM AUTHOR]

Published
2024
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3. List of Contributors

Author

Abere, V.D., primary, Adeosun, S.O., additional, Afonja, A.A., additional, Ahmad, Zakiah, additional, Ahmed, Tanvir, additional, Akinluwade, K.J., additional, Akinwole, I.E., additional, Akpan, E.I., additional, Anraku, Makoto, additional, Antony, Nitheesh, additional, Arshad, Muhammad, additional, Azizi, Mahdieh, additional, Bajpai, Anjali, additional, Becenen, Nilgün, additional, Bertuol, Daniel Assumpção, additional, Biswas, Shanta, additional, Ciro, Yhors, additional, Cletus, Odili, additional, Copello, Guillermo Javier, additional, Erdoğan, Sevil, additional, Esan, T.A., additional, Farinha, Inês, additional, Fernandes, Susana C.M., additional, Fernández-Marín, Rut, additional, Fındık, Elif Ecem, additional, Freitas, Filomena, additional, Gbenebor, O.P., additional, Gebicki, Janusz M., additional, Gomes, Joana M., additional, Gond, Laxmi, additional, Haque, Papia, additional, Hernández-Rangel, Adriana, additional, Hidalgo-Moyle, Joseline J., additional, Hirayama, Fumitoshi, additional, Hirsch, Daniela Belén, additional, Hoseini, Mostafa Haji Molla, additional, Hossain, Mohammad Rahat, additional, Huang, Wei, additional, Ibitoye, S.A., additional, Ifuku, Shinsuke, additional, Imasogie, B.I., additional, Iohara, Daisuke, additional, Islam, Md. Minhajul, additional, Islam, Md. Sazedul, additional, Jiang, Xulin, additional, Kamilya, Dibyendu, additional, Khan, Md. Idrish Raja, additional, Labidi, Jalel, additional, Lopes, Poliana Pollizello, additional, Maleki, Gisoo, additional, Mallik, Abul K., additional, McReynolds, Colin, additional, Milani, Jafar M., additional, Naeli, Mohammad Hossein, additional, Oluwasegun, K.M., additional, Otagiri, Masaki, additional, Oyatogun, A.O., additional, Oyatogun, G.M., additional, Panonnummal, Rajitha, additional, Popoola, A.P.I., additional, Pottathara, Yasir Beeran, additional, Pouriran, Ramin, additional, Pradhan, Preeti, additional, Pradhan, Rehan Ali, additional, Prado-Prone, Gina, additional, Rahman, Md. Shirajur, additional, Rahman, Mohammed Mizanur, additional, Reis, Rui L., additional, Rodrigues, Luísa C., additional, Rojas, John, additional, Sabitha, M., additional, Sadeghi, Sahar, additional, Sakib, Md. Nurus, additional, Salamanca, Constaín H., additional, Sánchez, Ma Ángeles Andrés, additional, Shahruzzaman, Md., additional, Shirai, Keiko, additional, Silva, Simone S., additional, Silva-Bermudez, Phaedra, additional, Soboyejo, W.O., additional, Sultana, Sabrina, additional, Sun, Weiqing, additional, Tanabe, Eduardo Hiromitsu, additional, Thomas, Sabu, additional, Tiyyagura, Hanuma Reddy, additional, Tovar-Jimenez, Gabriel Ibrahin, additional, Ullah, Aman, additional, Urtasun, Nicolás, additional, Villanueva, María Emilia, additional, Wolman, Federico Javier, additional, Xie, Cong, additional, Yarce, Cristian J., additional, and Zubair, Muhammad, additional

Published
2020
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