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1. Association between O-GlcNAc levels and platelet function in obese insulin-resistant subjects

Author

Hernández-Huerta, María Teresa, Martínez-Cruz, Ruth, Pérez-Campos Mayoral, Laura, Pina-Canseco, María del Socorro, Solórzano-Mata, Carlos Josué, Martínez-Cruz, Margarito, Vásquez Martínez, Itzel Patricia, Zenteno, Edgar, Laguna Barrios, Luis Ángel, Matias-Cervantes, Carlos Alberto, Pérez-Campos Mayoral, Eduardo, and Pérez-Campos, Eduardo

Published
2024
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2. Agreement on the Prevalence of Body Mass Index (BMI) in Mexican Children and Adolescents Using Different International References.

Author

Santiago-Arango, Marisol, Pérez-Campos, Eduardo, Porras-Chaparro, Ivan, Ruiz-Rosado, Juan de Dios, Martínez Ruiz, Héctor, Cabrera-Fuentes, Héctor A., Mayoral, Eduardo Pérez-Campos, Martínez-Cruz, Margarito, Hernández-Huerta, María Teresa, and Pérez-Campos Mayoral, Laura

Abstract

(1) Background: Obesity and overweight are defined as an abnormal or excessive accumulation of fat that can be harmful to health. These are conditions that can lead to a lifetime of diseases, including cancer, diabetes, and heart disease. The diagnosis of overweight and obesity in children and adolescents depends on the international reference used. (2) Objectives: In this study aimed to determine the level of concordance of the prevalence of underweight, normal weight, overweight, and obesity were estimated with three international references in Mexican children and adolescents between 2 and 18 years of age. (3) Methods: We used specific the body mass index (BMI) cut-off points of the ENSANUT Continua 2022 database. The weight category was measured using the World Health Organization (WHO) criteria (<−2 standard deviation (SD), underweight; −2 and +0.99 SD, normal weight; +1 and +1.99 SD, overweight; and ≥+2 SD, obesity); Centers for Disease Control and Prevention (CDC) criteria (

Published
2025
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3. Bactericidal/Permeability-Increasing Protein (BPI), a Novel Antimicrobial Molecule in Human Breast Milk with Immune Potential.

Author

Aquino-Domínguez, Alba Soledad, de los Ángeles Romero-Tlalolini, María, Torres-Aguilar, Honorio, Rodríguez-Alba, Juan Carlos, Martínez-Martínez, Lucia Lourdes, Sánchez-Peña, Francisco Javier, Hernández-Huerta, María Teresa, Elizarrarás-Rivas, Jesús, Tapia-Pastrana, Gabriela, Gómez-López, Melisa, Cruz-Martínez, Elsa, Hernández-Corrales, Uriel Eleazar, and Aguilar-Ruiz, Sergio Roberto

Subjects
BREAST milk, ESCHERICHIA coli, EPITHELIAL cells, COLOSTRUM, IMMUNE system
Abstract

Breast milk is a fluid of vital importance during the first stages of life of the newborn since, in addition to providing nutrients, it also contains cells and molecules of the immune system, which protect the neonate from infection and, at the same time, modulate the establishment of the microbiota. Bactericidal/permeability-increasing protein (BPI) is relevant in preventing disease and sepsis in neonates. Therefore, the following work aimed to demonstrate the presence of BPI in the different stages of breast milk and its possible immune functions. Our results demonstrate for the first time the presence of soluble BPI and leukocytes and epithelial cells containing it, primarily in the colostrum stage. Using BPI at concentrations typical of colostrum, we observed that it reduces the growth of two distinct E. coli strains, enhances the uptake of these bacteria by monocytes, and suppresses the secretion of the proinflammatory cytokine interleukin (IL)-8 in infected intestinal cells. These findings suggest that BPI transferred via colostrum from mother to newborn may play a significant role in providing antimicrobial and anti-inflammatory protection during the early stages of life. [ABSTRACT FROM AUTHOR]

Published
2025
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4. Immunothrombotic dysregulation in chagas disease and COVID-19: a comparative study of anticoagulation

Author

Pérez-Campos Mayoral, Laura, Hernández-Huerta, María Teresa, Papy-García, Dulce, Barritault, Denis, Zenteno, Edgar, Sánchez Navarro, Luis Manuel, Pérez-Campos Mayoral, Eduardo, Matias Cervantes, Carlos Alberto, Martínez Cruz, Margarito, Mayoral Andrade, Gabriel, López Cervantes, Malaquías, Vázquez Martínez, Gabriela, López Sánchez, Claudia, Pina Canseco, Socorro, Martínez Cruz, Ruth, and Pérez-Campos, Eduardo

Published
2021
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7. LOX-1 in Cardiovascular Disease: A Comprehensive Molecular and Clinical Review

Author

Sánchez-León, Maria Eugenia, primary, Loaeza-Reyes, Karen Julissa, additional, Matias-Cervantes, Carlos Alberto, additional, Mayoral-Andrade, Gabriel, additional, Pérez-Campos, Eduardo L., additional, Pérez-Campos-Mayoral, Laura, additional, Hernández-Huerta, María Teresa, additional, Zenteno, Edgar, additional, Pérez-Cervera, Yobana, additional, and Pina-Canseco, Socorro, additional

Published
2024
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8. Targeting Neutrophil Extracellular Trap Formation: Exploring Promising Pharmacological Strategies for the Treatment of Preeclampsia

Author

Hernández González, Leticia Lorena, primary, Pérez-Campos Mayoral, Laura, additional, Hernández-Huerta, María Teresa, additional, Mayoral Andrade, Gabriel, additional, Martínez Cruz, Margarito, additional, Ramos-Martínez, Edgar, additional, Pérez-Campos Mayoral, Eduardo, additional, Cruz Hernández, Víctor, additional, Antonio García, Ismael, additional, Matias-Cervantes, Carlos Alberto, additional, Avendaño Villegas, Miriam Emily, additional, Lastre Domínguez, Carlos Mauricio, additional, Romero Díaz, Carlos, additional, Ruiz-Rosado, Juan de Dios, additional, and Pérez-Campos, Eduardo, additional

Published
2024
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9. Attention to health care in the context of instability. In health care for women international.

Author

Reyes-Flores, Adriana, Ramírez-Ramírez, Rafael, Pérez-Campos, Eduardo, Pérez-Campos Mayoral, Laura, Hernández-Huerta, María Teresa, and Pérez-Campos Mayoral, Eduardo

Subjects
EMPATHY, STEREOTYPES, EQUALITY, COMPASSION, WOMEN'S health, CHEMICAL burns, SOCIAL support, ACIDS, GENDER-based violence, ABUSED women
Abstract

In Mexico, the first attack dates back to 1988, but it was not identified until 2022. This violence remained invisible and minimized, but since then 42 acid attacks against women have been recorded, of which 5 victims died as a result of the attack and its medical complications. We think that families should be educated to eliminate misogyny in families and ensure that women are valued equally as men. We also think that education from childhood, questioning one's own beliefs, challenging stereotypes and gender roles, deconstructing prejudices, reporting, and acting with empathy and compassion are fundamental in a society with gender equity. [ABSTRACT FROM AUTHOR]

Published
2025
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10. Interaction of Spike protein and lipid membrane of SARS-CoV-2 with Ursodeoxycholic acid, an in-silico analysis

Author

Rodal Canales, Francisco Javier, Pérez-Campos Mayoral, Laura, Hernández-Huerta, María Teresa, Sánchez Navarro, Luis Manuel, Matias-Cervantes, Carlos Alberto, Martínez Cruz, Margarito, Cruz Parada, Eli, Zenteno, Edgar, Ramos-Martínez, Edgar Gustavo, Pérez-Campos Mayoral, Eduardo, Romero Díaz, Carlos, and Pérez-Campos, Eduardo

Published
2021
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11. O-GlcNAcylation: Crosstalk between Hemostasis, Inflammation, and Cancer.

Author

Vásquez Martínez, Itzel Patricia, Pérez-Campos, Eduardo, Pérez-Campos Mayoral, Laura, Cruz Luis, Holanda Isabel, Pina Canseco, María del Socorro, Zenteno, Edgar, Bazán Salinas, Irma Leticia, Martínez Cruz, Margarito, Pérez-Campos Mayoral, Eduardo, and Hernández-Huerta, María Teresa

Subjects
POST-translational modification, INFLAMMATION, PROGNOSTIC tests, TRANSCRIPTION factors, CELLULAR signal transduction, NF-kappa B
Abstract

O-linked β-N-acetylglucosamine (O-GlcNAc, O-GlcNAcylation) is a post-translational modification of serine/threonine residues of proteins. Alterations in O-GlcNAcylation have been implicated in several types of cancer, regulation of tumor progression, inflammation, and thrombosis through its interaction with signaling pathways. We aim to explore the relationship between O-GlcNAcylation and hemostasis, inflammation, and cancer, which could serve as potential prognostic tools or clinical predictions for cancer patients' healthcare and as an approach to combat cancer. We found that cancer is characterized by high glucose demand and consumption, a chronic inflammatory state, a state of hypercoagulability, and platelet hyperaggregability that favors thrombosis; the latter is a major cause of death in these patients. Furthermore, we review transcription factors and pathways associated with O-GlcNAcylation, thrombosis, inflammation, and cancer, such as the PI3K/Akt/c-Myc pathway, the nuclear factor kappa B pathway, and the PI3K/AKT/mTOR pathway. We also review infectious agents associated with cancer and chronic inflammation and potential inhibitors of cancer cell development. We conclude that it is necessary to approach both the diagnosis and treatment of cancer as a network in which multiple signaling pathways are integrated, and to search for a combination of potential drugs that regulate this signaling network. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Non-Coding RNAs and Innate Immune Responses in Cancer.

Author

Díaz, Carlos Romero, Hernández-Huerta, María Teresa, Mayoral, Laura Pérez-Campos, Villegas, Miriam Emily Avendaño, Zenteno, Edgar, Cruz, Margarito Martínez, Mayoral, Eduardo Pérez-Campos, del Socorro Pina Canseco, María, Andrade, Gabriel Mayoral, Castellanos, Manuel Ángeles, Matías Salvador, José Manuel, Cruz Parada, Eli, Martínez Barras, Alexis, Cruz Fernández, Jaydi Nora, Scott-Algara, Daniel, and Pérez-Campos, Eduardo

Subjects
SMALL interfering RNA, LINCRNA, NON-coding RNA, GENE expression, NATURAL immunity
Abstract

Non-coding RNAs (ncRNAs) and the innate immune system are closely related, acting as defense mechanisms and regulating gene expression and innate immunity. Both are modulators in the initiation, development and progression of cancer. We aimed to review the major types of ncRNAs, including small interfering RNAs (siRNAs), microRNAs (miRNAs), piwi-interacting RNAs (piRNAs), and long non-coding RNAs (lncRNAs), with a focus on cancer, innate immunity, and inflammation. We found that ncRNAs are closely related to innate immunity, epigenetics, chronic inflammation, and cancer and share properties such as inducibility, specificity, memory, and transfer. These similarities and interrelationships suggest that ncRNAs and modulators of trained immunity, together with the control of chronic inflammation, can be combined to develop novel therapeutic approaches for personalized cancer treatment. In conclusion, the close relationship between ncRNAs, the innate immune system, and inflammation highlights their importance in cancer pathways and their potential as targets for novel therapeutic strategies. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Interaction of piRNA-like sequences from the 3′-UTR of SARS-CoV-2 with mRNA regions

Author

Pérez-Campos Mayoral, Laura, primary, Hernández-Huerta, María Teresa, additional, Romero Díaz, Carlos, additional, Matias-Cervantes, Carlos Alberto, additional, Pérez-Campos Mayoral, Eduardo, additional, Martínez Cruz, Margarito, additional, Ruiz-Rosado, Juan de Dios, additional, Ramos Martínez, Edgar Gustavo, additional, Sánchez Medina, Marco Antonio, additional, and Pérez-Campos, Eduardo, additional

Published
2023
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16. Molecules in seminal plasma related to platelets in preeclampsia

Author

García-Montalvo, Iván Antonio, Mayoral Andrade, Gabriel, Perez-Campos Mayoral, Laura, Pina Canseco, Socorro, Martinez Cruz, Ruth, Martínez-Cruz, Margarito, Zenteno, Edgar, Perez-Campos Mayoral, Eduardo, Velasco Gallegos, Itandehui, Hernandez-Huerta, Maria Teresa, Matias-Perez, Diana, and Pérez-Campos, Eduardo

Published
2016
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17. El índice de legibilidad y el factor de impacto en artículos recientes sobre covid-19

Author

Cruz Parada, Eli, primary, Hernández Huerta, María Teresa, additional, Romero Díaz, Carlos, additional, Martínez Cruz, Margarito, additional, -Campos Mayoral, Laura Pérez, additional, -Campos Mayoral, Eduardo Pérez, additional, Matias Cervantes, Carlos Alberto, additional, Martínez Martínez, Lucia L., additional, and Pérez Campos, Eduardo L., additional

Published
2023
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18. The Role of B Cell and T Cell Glycosylation in Systemic Lupus Erythematosus

Author

Ramos-Martínez, Ivan, primary, Ramos-Martínez, Edgar, additional, Cerbón, Marco, additional, Pérez-Torres, Armando, additional, Pérez-Campos Mayoral, Laura, additional, Hernández-Huerta, María Teresa, additional, Martínez-Cruz, Margarito, additional, Pérez-Santiago, Alma Dolores, additional, Sánchez-Medina, Marco Antonio, additional, García-Montalvo, Iván Antonio, additional, Zenteno, Edgar, additional, Matias-Cervantes, Carlos Alberto, additional, Ojeda-Meixueiro, Víctor, additional, and Pérez-Campos, Eduardo, additional

Published
2023
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20. The role of nursing in the prevention of catheter-associated infections in hemodialysis: A literature review

Author

Echeverría-Vásquez, Patricia, Ramos-Martínez, Ivan, Hernández-González, Leticia, Pérez Campos, Eduardo, Pérez Campos Mayoral, Laura, Hernández-Huerta, María Teresa, and Ramos-Martínez, Edgar

Subjects
hepatitis viral, infecciones, viral hepatitis, nursing intervention, Catéter venoso central, bacteriemia, intervención de enfermería, infections, bacteremia, Central venous catheter
Abstract

RESUMEN Introducción: Las infecciones asociadas al catéter venoso central son la principal causa de morbilidad y mortalidad en los pacientes en hemodiálisis. El personal de enfermería es el que principalmente realiza la manipulación del acceso vascular en el momento de la inserción, mantenimiento o retirada del catéter. El papel del personal de enfermería es fundamental en la prevención de infecciones locales y sistémicas. Objetivo: Determinar las principales intervenciones implementadas por el personal de enfermería para reducir el número de infecciones asociadas a catéter en hemodiálisis. Metodología: Se realizó una revisión bibliográfica en el periodo agosto 2021 a enero 2022. La búsqueda fue realizada en bases de datos como PubMed, Scopus, Access Medicine, Wed of Science, Medigraphic, EBSCO, Science Direct, y Google Scholar. Los términos de búsqueda fueron: (infections) AND (hemodialysis) AND (nursing). Resultados: Se seleccionaron 94 estudios de los cuales se identificaron las principales medidas para la prevención de infecciones durante la instalación, mantenimiento y remoción del catéter para hemodiálisis. Ademas, se identificaron las limitantes de la evidencia para algunos procedimientos y los puntos que requieren mayor investigación. Conclusiones: Las principales estrategias utilizadas para reducir la bacteriemia relacionada con los catéteres en hemodiálisis son: 1) el uso estricto de medidas higiénicas por parte del personal sanitario, 2) el uso de profilaxis antibiótica en el lugar de salida 3) la impregnación en la luz del catéter con solución antimicrobiana de bloqueo, 4) la formación continua y 5) la aplicación de un protocolo. ABSTRACT Introduction: Central venous catheter-associated infections are the main cause of morbidity and mortality in hemodialysis patients. The nursing staff is the one who mainly performs the manipulation of the vascular access at the time of insertion, maintenance or removal of the catheter. The role of the nursing staff is fundamental in the prevention of local and systemic infections. Objective: To determine the main interventions implemented by nursing staff to reduce the number of catheter-associated infections in hemodialysis. Methodology: A literature review was conducted from August 2021 to January 2022. A search was conducted in databases such as PubMed, Scopus, Access Medicine, Wed of Science, Medigraphic, EBSCO, Science Direct, and Google Scholar. The search terms were: (infections) AND (hemodialysis) AND (nursing). Results: Ninety-four studies were selected from which the main measures for infection prevention during hemodialysis catheter installation, maintenance, and removal were identified. In addition, we identified the limitations of the evidence for some procedures and the points requiring further research. Conclusions: The main strategies used to reduce catheter-related bacteremia in hemodialysis are 1) strict use of hygienic measures by healthcare personnel, 2) use of antibiotic prophylaxis at the exit site 3) impregnation of the catheter lumen with antimicrobial blocking solution, 4) continuous training, and 5) implementation of a protocol., {"references": ["Flores JC, Alvo M, Borja H, Morales J, Vega J, Z\u00fa\u00f1iga C, et al. Enfermedad renal cr\u00f3nica: Clasificaci\u00f3n, identificaci\u00f3n, manejo y complicaciones. Rev M\u00e9d Chile. 2009; 137(1): 137-77. DOI: 10.4067/S0034-98872009000100026", "Candelaria-Brito JC, Guti\u00e9rrez-Guti\u00e9rrez C, Bayarre-Vea HD, Acosta-Cruz C, Montes de Oca DM, Labrador-Maz\u00f3n O. Caracterizaci\u00f3n de la enfermedad renal cr\u00f3nica en adultos mayores. Rev Colomb Nefrol. 2018; 5(2): 166-78. 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J Am Soc Echocardiogr. 2017; 30(7): 639-46.e8. DOI: 10.1016/j.echo.2017.03.007", "Mondrag\u00f3n BJ, Mondrag\u00f3n BD, Medina CM, Medina CD. Endocarditis Infecciosa. Rev Clin Esc Med. 2019; 9(2): 105-11. Available in: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=87067", "Villafuerte-Mollinedo P, Torrez-Cruz KM, Viruez-Soto JL, Ilaya-Garavito P. Endocarditis bacteriana a prop\u00f3sito de un caso. Cuad Hosp Cl\u00edn. 2020; 61(1): 85-94. Available in: http://www.scielo.org.bo/scielo.php?script=sci_arttext&pid=S1652-67762020000100007", "Ruiz-Calero RM, Cancho B, Mart\u00edn MV, Cid MC, Gal\u00e1n J, Fern\u00e1ndez MA, et al. \u00bfCu\u00e1ndo puede ser \u00fatil buscar VHB oculto en pacientes en hemodi\u00e1lisis? Nefrolog\u00eda. 2020; 40(2): 115-9. DOI: 10.1016/j.nefro.2019.07.001", "Winston A, Wurcel AG, Gordon C, Goyal N. Viral hepatitis in patients on hemodialysis. Semin Dial. 2020; 33(3): 254-62. DOI: 10.1111/sdi.12882", "Trevizoli JE, De Paula R, Ribeiro LF, Amorim R, Birche M, Sampaio L, et al. Hepatitis C is less aggressive in hemodialysis patients than in nonuremic patients. Clin J Am Soc Nephrol. 2008; 3(5): 1385-90. DOI: 10.2215/CJN.01330308", "Calle L, Tajada P, Villalta VM, Avell\u00f3n A, Rodr\u00edguez A, Heras M, et al. Reactivaci\u00f3n silenciosa del virus de la hepatitis B en paciente que reinicia di\u00e1lisis tras trasplante renal. \u00bfC\u00f3mo podemos prevenirlo o anticiparlo en el diagn\u00f3stico? Nefrolog\u00eda. 2020; 40(4): 477-9. DOI: 10.1016/j.nefro.2019.06.006", "Garthwaite E, Reddy V, Douthwaite S, Lines S, Tyerman K, Eccles J. Clinical practice guideline management of blood borne viruses within the haemodialysis unit. BMC Nephrol. 2019; 20(1): 388. DOI: 10.1186/s12882-019-1529-1", "Chac\u00f3n-Quesada T, Rohde V, von der Brelie C. Less surgical site infections in neurosurgery during COVID-19 times-one potential benefit of the pandemic? Neurosurg Rev. 2021; 44: 3421-5. DOI: 10.1007/s10143-021-01513-5", "Heidempergher M, Sabiu G, Orani MA, Tripepi G, Gallieni M. Targeting COVID-19 prevention in hemodialysis facilities is associated with a drastic reduction in central venous catheter-related infections. J Nephrol. 2021; 34(2): 345-53. DOI: 10.1007/s40620-020-00900-3", "Craswell A, Massey D, Wallis M, Sriram D, Gray NA, Kotwal S. Current practice in dialysis central venous catheter management: Multi-disciplinary renal team perspectives. Nephrology (Carlton). 2020; 25(5): 406-12. DOI: 10.1111/nep.13626", "Bayoumi M, Mahmoud N. Effect of education program on nurses' knowledge and practice regarding care of central venous line in pediatric hemodialysis: evidence-based practice guidelines. Egypt Nurs J. 2017; 14(2): 87-99.", "Conwell P, Aniskiewicz M, Ghidini J, DeVaux L, Perazella M, Giullian J. A Hospital-Based Program to Reduce Central Line-Associated Bloodstream Infections among Hospitalized Patients Receiving Hemodialysis Using a Central Venous Catheter for Vascular Access. Nephrol Nurs J. 2019; 46(6): 587-90. Available in: https://www.researchgate.net/publication/338163802_A_Hospital-Based_Program_to_Reduce_Central_Line-Associated_Bloodstream_Infections_among_Hospitalized_Patients_Receiving_Hemodialysis_Using_a_Central_Venous_Catheter_for_Vascular_Access", "Yang Z, Ma X, Chen Y, Cao Y, Li Q, Pan X, et al. Effects of a Quality Improvement Program to Reduce Central Venous Catheter-Related Infections in Hemodialysis Patients. Am J Med Sci. 2021; 361(4): 461-8. DOI: 10.1016/j.amjms.2020.10.018", "Crehuet I, Bern\u00e1rdez MA. Aplicaci\u00f3n de protocolos en enfermer\u00eda: la mejor barrera contra las infecciones de los cat\u00e9teres de hemodi\u00e1lisis. Enferm Nefrol. 2018; 21(3): 263-8. DOI: 10.4321/s2254-28842018000300008", "Sahni N, Biswal M, Gandhi K, Kaur K, Saini V, Yaddanapudi LN. Effect of Intensive Education and Training of Nurses on Ventilator-associated Pneumonia and Central Line-associated Bloodstream Infection Incidence in Intensive Care Unit at a Tertiary Care Center in North India. Indian J Crit Care Med. 2017; 21(11): 779-82. DOI: 10.4103/ijccm.IJCCM_259_17", "Perin DC, Erdmann AL, Higashi GDC, Dal Sasso GTM. Evidence-based measures to prevent central line-associated bloodstream infections: a systematic review. Rev Lat Am Enfermagem. 2016; 24: e2787. DOI: 10.1590/1518-8345.1233.2787", "Fox C, Wavra T, Drake DA, Mulligan D, Pacheco Y, Nelson C, et al. Use of a patient hand hygiene protocol to reduce hospital-acquired infections and improve nurses' hand washing. Am J Crit Care. 2015; 24(3): 216-24. DOI: 10.4037/ajcc2015898", "\u00c1lvarez-Lerma F, Oliva G, Ferrer JM, Riera A, Palomar M. Resultados de la aplicaci\u00f3n del proyecto Bacteriemia Zero en Catalunya. Med Clin (Barc). 2014; 143 (Suppl. 1): 11-6. DOI: 10.1016/j.medcli.2014.07.006", "Pronovost P, Needham D, Berenholtz S, Sinopoli D, Chu H, Cosgrove S, et al. An Intervention to Decrease Catheter-Related Bloodstream Infections in the ICU. N Engl J Med. 2006; 355(26): 2725-32. DOI: 10.1056/NEJMoa061115", "Zhao T, Liu H, Han J. Ethanol lock is effective on reducing the incidence of tunneled catheter-related bloodstream infections in hemodialysis patients: a systematic review and meta-analysis. Int Urol Nephrol. 2018; 50(9): 1643-52. DOI: 10.1007/s11255-018-1855-4", "Echevarria-Uraga JJ, Garc\u00eda-Garai N, Mu\u00f1oz-Gonz\u00e1lez RI. Accesos venosos para hemodi\u00e1lisis: abordaje yugular. Di\u00e1lisis y Traspl. 2014; 35(4): 163-8. DOI: 10.1016/j.dialis.2014.11.003", "Kahn JM, Gunn SR, Lorenz HL, Alvarez J, Angus DC. Impact of nurse-led remote screening and prompting for evidence-based practices in the ICU*. Crit Care Med. 2014; 42(4): 896-904. DOI: 10.1097/CCM.0000000000000052", "Pedrolo E, Danski MTR, Vayego SA. Chlorhexidine and gauze and tape dressings for central venous catheters: a randomized clinical trial. Rev Lat Am Enfermagem. 2014; 22(5): 764-71. DOI: 10.1590/0104-1169.3443.2478", "Munoz-Price LS, Dezfulian C, Wyckoff M, Lenchus J, Rosalsky M, Brinbach DJ, Arheart K. Effectiveness of stepwise interventions targeted to decrease central catheter-associated bloodstream infections. Crit Care Med. 2012; 40(5): 1464-9. DOI: 10.1097/CCM.0b013e31823e9f5b", "Zhang J, Wang B, Li R, Ge L, Chen K-H, Tian J. Does antimicrobial lock solution reduce catheter-related infections in hemodialysis patients with central venous catheters? A Bayesian network meta-analysis. Int Urol Nephrol. 2017; 49(4): 701-16. DOI: 10.1007/s11255-016-1490-x", "Shah HN, Schwartz JL, Luna G, Cullen DL. Bathing With 2% Chlorhexidine Gluconate: Evidence and Costs Associated With Central Line-Associated Bloodstream Infections. Crit Care Nurs Q. 2016; 39(1): 42-50. DOI: 10.1097/CNQ.0000000000000096", "McCarthy CJ, Behravesh S, Naidu SG, Oklu R. Air Embolism: Practical Tips for Prevention and Treatment. J Clin Med. 2016; 5(11): 93. DOI: 10.3390/jcm5110093", "Ingram P, Sinclair L, Edwards T. The safe removal of central venous catheters. Nurs Stand. 2006; 20(49): 42-6. DOI: 10.7748/ns2006.08.20.49.42.c4483", "Wysoki MG, Covey A, Pollak J, Rosenblatt M, Aruny J, Denbow N. Evaluation of various maneuvers for prevention of air embolism during central venous catheter placement. J Vasc Interv Radiol. 2001; 12(6): 764-6. DOI: 10.1016/s1051-0443(07)61451-1", "Enriquez VA, Hern\u00e1ndez CC, Carrillo SC, Esponda JG. Instalaci\u00f3n de cat\u00e9ter venoso central por ultrasonido. Experiencia de la Unidad de Terapia Intensiva del Hospital \u00c1ngeles Pedregal. Acta Med. 2017; 15(2): 118-22. DOI: 10.35366/72343", "Guimaraes G, Mendoza IY, Werli-Alvarenga A, Ameida J, Dos Reis A, Oliveira J, et al. Diagn\u00f3stico, resultado e interven\u00e7\u00e3o de enfermagem no paciente com cateter para hemodi\u00e1lise. Rev Enferm UFPE line. 2017; 11(11): 4334-42. Available in: https://periodicos.ufpe.br/revistas/revistaenfermagem/article/view/23544/24934", "C\u00e1rcoba N, Ce\u00f1a S. Cateterizaci\u00f3n venosa central de acceso perif\u00e9rico mediante t\u00e9cnica seldinger modificada en la urgencia hospitalaria. Enferm Glob. 2010; 20: 1-4. Available in: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1695-61412010000300015", "Saad TF. Central Venous Dialysis Catheters: Catheter-Associated Infection. Semin Dial. 2001; 14(6): 446-51. DOI: 10.1046/j.1525-139x.2001.00110.x", "Aguinaga A, Del Pozo JL. Infecci\u00f3n asociada a cat\u00e9ter en hemodi\u00e1lisis: diagn\u00f3stico, tratamiento y prevenci\u00f3n. Nefrolog\u00eda. 2011; 4(2): 1-10. DOI: 10.3265/NefroPlus.pre2011.Jun.11016", "Andreu D, Hidalgo MA, Moreno C. Eventos infecciosos en pacientes en hemodi\u00e1lisis. Enferm Nefrol. 2015; 18(1): 54-6. Available in: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2254-28842015000100008", "Andreu D, Hidalgo MA, Moreno C. Eventos infecciosos en pacientes en hemodi\u00e1lisis. Enferm Nefrol. 2015; 18(1): 54-6. Available in: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2254-28842015000100008", "Bra\u00f1as P, Morales E, R\u00edos F, Sanz F, Guti\u00e9rrez E, Quintanilla N, et al. Usefulness of endoluminal catheter colonization surveillance cultures to reduce catheter-related bloodstream infections in hemodialysis. Am J Infect Control. 2014; 42(11): 1182-7. DOI: 10.1016/j.ajic.2014.07.022", "Jaffer Y, Selby NM, Taal MW, Fluck RJ, McIntyre CW. A meta-analysis of hemodialysis catheter locking solutions in the prevention of catheter-related infection. Am J Kidney Dis. 2008; 51(2): 233-41. DOI: 10.1053/j.ajkd.2007.10.038", "Labriola L, Crott R, Jadoul M. Preventing haemodialysis catheter-related bacteraemia with an antimicrobial lock solution: a meta-analysis of prospective randomized trials. Nephrol Dial Transplant. 2008; 23(5): 1666-72. DOI: 10.1093/ndt/gfm847", "Yahav D, Rozen-Zvi B, Gafter-Gvili A, Leibovici L, Gafter U, Paul M. Antimicrobial lock solutions for the prevention of infections associated with intravascular catheters in patients undergoing hemodialysis: systematic review and meta-analysis of randomized, controlled trials. Clin Infect Dis. 2008; 47(1): 83-93. DOI: 10.1086/588667", "Wang R, Song S, Harada K, Ghazanfari F, Badgwell B, Pool M, et al. Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response. Gut. 2020; 69(1): 18-31. DOI: 10.1136/gutjnl-2018-318070", "Nori US, Manoharan A, Yee J, Besarab A. Comparison of low-dose gentamicin with minocycline as catheter lock solutions in the prevention of catheter-related bacteremia. Am J Kidney Dis. 2006; 48(4): 596-605. DOI: 10.1053/j.ajkd.2006.06.012", "Saxena AK, Panhotra BR, Sundaram DS, Al-Hafiz A, Naguib M, Venkateshappa CK, et al. Tunneled catheters' outcome optimization among diabetics on dialysis through antibiotic-lock placement. Kidney Int. 2006; 70(9): 1629-35. DOI: 10.1038/sj.ki.5001776", "Kim SH, Song KI, Chang JW, Kim SB, Sung SA, Jo SK, et al. Prevention of uncuffed hemodialysis catheter-related bacteremia using an antibiotic lock technique: a prospective, randomized clinical trial. Kidney Int. 2006; 69(1): 161-4. DOI: 10.1038/sj.ki.5000012", "Betjes MGH, van Agteren M. Prevention of dialysis catheter-related sepsis with a citrate-taurolidine-containing lock solution. Nephrol Dial Transplant. 2004; 19(6): 1546-51. DOI: 10.1093/ndt/gfh014", "McIntyre CW, Hulme LJ, Taal M, Fluck RJ. Locking of tunneled hemodialysis catheters with gentamicin and heparin. Kidney Int. 2004;66(2):801-805. doi:10.1111/j.1523-1755.2004.00806.x", "Le Corre I, Delorme M, Cournoyer S. A prospective, randomized trial comparing a transparent dressing and a dry gauze on the exit site of long term central venous catheters of hemodialysis patients. J Vasc Access. 2003; 4(2): 56-61. DOI: 10.1177/112972980300400205", "Lee Y-M, Moon C, Kim YJ, Lee HJ, Lee MS, Park K-H. Clinical i

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2022
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21. Associations of Dynapenic Obesity and Sarcopenic Obesity with the Risk of Complications in COVID-19

Author

Pérez-Campos Mayoral, Laura, primary, Matias-Cervantes, Carlos Alberto, additional, Pérez-Campos, Eduardo, additional, Romero Díaz, Carlos, additional, Laguna Barrios, Luis Ángel, additional, Pina Canseco, María del Socorro, additional, Martínez Cruz, Margarito, additional, Pérez-Campos Mayoral, Eduardo, additional, Solórzano Mata, Carlos Josué, additional, Rodal Canales, Francisco Javier, additional, Martínez Ruíz, Héctor, additional, and Hernández-Huerta, María Teresa, additional

Published
2022
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23. PHYTOCHEMICAL STUDY AND EVALUATION OF THE ANTIAGGREGATING EFFECT OF AQUEOUS AND ETHANOL EXTRACTS OF THE FUNGUS Amanita muscaria

Author

Vásquez-Martínez, Itzel Patricia, primary, Laguna-Barrios, Luis Ángel, additional, Mayoral, Laura Pérez-Campos, additional, Pina-Canseco, María del Socorro, additional, Pérez-Campos, Eduardo, additional, Mayoral, Eduardo Pérez-Campos, additional, Matias-Cervantes, Carlos Alberto, additional, Alpuche-Osorno, Juan, additional, and Hernández-Huerta, María Teresa, additional

Published
2022
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24. 3′-UTR of the SARS-CoV-2 genome as a possible source of piRNAs

Author

Hernández-Huerta, María Teresa, primary, Pérez-Campos Mayoral, Laura, additional, Matias-Cervantes, Carlos Alberto, additional, Romero Díaz, Carlos, additional, Cruz Parada, Eli, additional, Pérez-Campos Mayoral, Eduardo, additional, Baltiérrez-Hoyos, Rafael, additional, Martínez Cruz, Margarito, additional, Mayoral Andrade, Gabriel, additional, and Pérez-Campos, Eduardo, additional

Published
2022
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25. Mechanisms of Immunothrombosis by SARS-CoV-2

Author

Hernández-Huerta, María Teresa, primary, Pérez-Santiago, Alma Dolores, additional, Pérez-Campos Mayoral, Laura, additional, Sánchez Navarro, Luis Manuel, additional, Rodal Canales, Francisco Javier, additional, Majluf-Cruz, Abraham, additional, Matias-Cervantes, Carlos Alberto, additional, Pérez-Campos Mayoral, Eduardo, additional, Romero Díaz, Carlos, additional, Mayoral-Andrade, Gabriel, additional, Martínez Cruz, Margarito, additional, Luna Ángel, Judith, additional, and Pérez-Campos, Eduardo, additional

Published
2021
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26. The influence of hydrogen ions on coagulation in traumatic brain injury, explored by molecular dynamics

Author

Romero Díaz, Carlos, primary, Mayoral, Laura Pérez Campos, additional, Hernández Huerta, María Teresa, additional, Majluf-Cruz, Abraham Salvador, additional, Plascencia Mora, Stephanie Elizabeth, additional, Pérez-Campos Mayoral, Eduardo, additional, Mayoral Andrade, Gabriel, additional, Martínez Cruz, Margarito, additional, Zenteno, Edgar, additional, Matias Cervantes, Carlos Alberto, additional, Vásquez Martínez, Gabriela, additional, Martínez Cruz, Ruth, additional, Ángel Reyes Franco, Miguel, additional, Cruz Parada, Eli, additional, Pina Canseco, Socorro, additional, and Pérez-Campos, Eduardo, additional

Published
2021
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27. Multiple Origins of Extracellular DNA Traps

Author

Ramos-Martínez, Edgar, primary, Hernández-González, Leticia, additional, Ramos-Martínez, Iván, additional, Pérez-Campos Mayoral, Laura, additional, López-Cortés, Georgina I., additional, Pérez-Campos, Eduardo, additional, Mayoral Andrade, Gabriel, additional, Hernández-Huerta, María Teresa, additional, and José, Marco V., additional

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2021
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28. Molecules and Prostaglandins Related to Embryo Tolerance

Author

Mayoral Andrade, Gabriel, primary, Vásquez Martínez, Gabriela, additional, Pérez-Campos Mayoral, Laura, additional, Hernández-Huerta, María Teresa, additional, Zenteno, Edgar, additional, Pérez-Campos Mayoral, Eduardo, additional, Martínez Cruz, Margarito, additional, Martínez Cruz, Ruth, additional, Matias-Cervantes, Carlos Alberto, additional, Meraz Cruz, Noemi, additional, Romero Díaz, Carlos, additional, Cruz-Parada, Eli, additional, and Pérez-Campos, Eduardo, additional

Published
2020
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29. Analysis of SARS‐CoV‐2 mutations in Mexico, Belize, and isolated regions of Guatemala and its implication in the diagnosis

Author

Hernández‐Huerta, María Teresa, primary, Pérez‐Campos Mayoral, Laura, additional, Romero Díaz, Carlos, additional, Martínez Cruz, Margarito, additional, Mayoral‐Andrade, Gabriel, additional, Sánchez Navarro, Luis Manuel, additional, Pina‐Canseco, María Del Socorro, additional, Cruz Parada, Eli, additional, Martínez Cruz, Ruth, additional, Pérez‐Campos Mayoral, Eduardo, additional, Pérez Santiago, Alma Dolores, additional, Vásquez Martínez, Gabriela, additional, Pérez‐Campos, Eduardo, additional, and Matias‐Cervantes, Carlos Alberto, additional

Published
2020
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32. TSH Levels in Subclinical Hypothyroidism in the 97.5th Percentile of the Population

Author

Pérez-Campos Mayoral, Laura, primary, Hernández-Huerta, María Teresa, additional, Mayoral-Andrade, Gabriel, additional, Pérez-Campos Mayoral, Eduardo, additional, Zenteno, Edgar, additional, Martínez-Cruz, Ruth, additional, Martínez Ruíz, Héctor, additional, Martínez Cruz, Margarito, additional, Pérez Santiago, Alma Dolores, additional, and Pérez-Campos, Eduardo, additional

Published
2020
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33. Aggregation and Molecular Properties of β-Glucosidase Isoform II in Chayote (Sechium edule)

Author

Cruz Rodríguez, Alberto, primary, Sánchez Esperanza, Fabiola Anaid, additional, Pérez-Campos, Eduardo, additional, Hernández-Huerta, María Teresa, additional, Pérez-Campos Mayoral, Laura, additional, Matias-Cervantes, Carlos Alberto, additional, Martínez Barras, Alexis, additional, Mayoral-Andrade, Gabriel, additional, Santos Pineda, Luis Ángel, additional, Díaz Barrita, Aymara Judith, additional, Zenteno, Edgar, additional, Romero Díaz, Carlos, additional, Martínez Cruz, Ruth, additional, Pérez-Campos Mayoral, Eduardo, additional, Bernabé Pérez, Edith Alhelí, additional, Pérez Santiago, Alma Dolores, additional, Pina-Canseco, María del Socorro, additional, and Martínez Cruz, Margarito, additional

Published
2020
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34. Analysis of SARS‐CoV‐2 mutations in Mexico, Belize, and isolated regions of Guatemala and its implication in the diagnosis.

Author

Hernández‐Huerta, María Teresa, Pérez‐Campos Mayoral, Laura, Romero Díaz, Carlos, Martínez Cruz, Margarito, Mayoral‐Andrade, Gabriel, Sánchez Navarro, Luis Manuel, Pina‐Canseco, María Del Socorro, Cruz Parada, Eli, Martínez Cruz, Ruth, Pérez‐Campos Mayoral, Eduardo, Pérez Santiago, Alma Dolores, Vásquez Martínez, Gabriela, Pérez‐Campos, Eduardo, and Matias‐Cervantes, Carlos Alberto

Subjects
SARS-CoV-2
Abstract

The genomic sequences of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) worldwide are publicly available and are derived from studies due to the increase in the number of cases. The importance of study of mutations is related to the possible virulence and diagnosis of SARS‐CoV‐2. To identify circulating mutations present in SARS‐CoV‐2 genomic sequences in Mexico, Belize, and Guatemala to find out if the same strain spread to the south, and analyze the specificity of the primers used for diagnosis in these samples. Twenty three complete SARS‐CoV‐2 genomic sequences, available in the GISAID database from May 8 to September 11, 2020 were analyzed and aligned versus the genomic sequence reported in Wuhan, China (NC_045512.2), using Clustal Omega. Open reading frames were translated using the ExPASy Translate Tool and UCSF Chimera (v.1.12) for amino acid substitutions analysis. Finally, the sequences were aligned versus primers used in the diagnosis of COVID‐19. One hundred and eighty seven distinct variants were identified, of which 102 are missense, 66 synonymous and 19 noncoding. P4715L and P5828L substitutions in replicase polyprotein were found, as well as D614G in spike protein and L84S in ORF8 in Mexico, Belize, and Guatemala. The primers design by CDC of United States showed a positive E value. The genomic sequences of SARS‐CoV‐2 in Mexico, Belize, and Guatemala present similar mutations related to a virulent strain of greater infectivity, which could mean a greater capacity for inclusion in the host genome and be related to an increased spread of the virus in these countries, furthermore, its diagnosis would be affected. [ABSTRACT FROM AUTHOR]

Published
2021
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35. Efecto de n-acetilglucosamina sobre plaquetas

Author

Pérez-Campos Mayoral, Laura, primary, Pina-Canseco, María del Socorro, additional, Pérez-Campos, Eduardo Lorenzo, additional, Hernández-Huerta, María Teresa, additional, Zenten´-Galindo, Edgar, additional, and Martínez-Cruz, Ruth, additional

Published
2017
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36. Relevance of a Customized Version of ChatGPT Explaining Laboratory Test Results in Patient Education.

Author

Ojeda Meixueiro, Víctor Hugo, Pérez-Campos Mayoral, Laura, Hernández Huerta, María Teresa, Matias-Cervantes, Carlos Alberto, Pérez Campos Mayoral, Eduardo, Cruz Parada, Elí, and Pérez-Campos, Eduardo

Subjects
*CHATGPT, *PATIENT education, *NATURAL language processing, *CHATBOTS, *ARTIFICIAL intelligence
Abstract

ChatGPT is an artificial intelligence (AI) chatbot application. In this study, we explore the creation and use of a customized version of ChatGPT designed specifically for patient education, called "Lab Explainer." Lab Explainer aims to simplify and clarify the results of complex laboratory tests for patients, using the sophisticated capabilities of AI in natural language processing; it analyses various laboratory test data and provides clear explanations and contextual information. The approach involved adapting OpenAI's ChatGPT model specifically to analyze laboratory test data. The results suggest that Lab Explainer has the potential to improve understanding by providing an interpretation of laboratory tests to the patient. In conclusion, the Lab Explainer can assist patient education by providing intelligible interpretations of laboratory tests. [ABSTRACT FROM AUTHOR]

Published
2024
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38. Should RT‐PCR be considered a gold standard in the diagnosis of COVID‐19?

Author

Hernández‐Huerta, María Teresa, Pérez‐Campos Mayoral, Laura, Sánchez Navarro, Luis Manuel, Mayoral‐Andrade, Gabriel, Pérez‐Campos Mayoral, Eduardo, Zenteno, Edgar, and Pérez‐Campos, Eduardo

Subjects
COVID-19 testing, COVID-19, SINGLE-photon emission computed tomography, COMPUTED tomography, SARS-CoV-2
Abstract

Should RT-PCR be considered a gold standard in the diagnosis of COVID-19? In reference to the comments by Dramé et al,1 that question the possibility of whether the reverse-transcriptase polymerase chain reaction (RT-PCR) for viral load should be considered a gold standard in the diagnosis of coronavirus disease 2019 (COVID-19). Imaging studies,8 such as SP 18 sp F-fluorodeoxyglucose positron emission tomography/computed tomography (CT) and SP 131 sp I single-photon emission computed tomography/CT, have been reported to show that asymptomatic subjects evolving to COVID-19 showed a metabolically active pattern of interstitial pneumonia. [Extracted from the article]

Published
2021
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40. Geographic and Ethnographic Variations of Hemoglobin A1C.

Author

Pérez-Campos Mayora, Eduardo, Pérez-Campos Mayoral, Laura, Mayoral-Andrade, Gabriel, Hernández-Huerta, María Teresa, Martínez Cruz, Margarito, and Pérez-Campos, Eduardo

Subjects
*TYPE 2 diabetes diagnosis, *PREDIABETIC state, *ETHNIC groups, *GLYCOSYLATED hemoglobin, *POPULATION geography, *DIAGNOSIS
Abstract

The authors comment on the geographic and ethnographic variations at hemoglobin A1C and discuss some known studies of diabetes with differences in geographical data. A study showed a very low A1C sensitivity in detecting type 2 diabetes mellitus or prediabetes in Middle-Eastern Iraq, Turkey, and Swedish ancestors. Other studies show that the sensitivity and specificity of A1C is very variable in different populations. Geographical reports with cut-off point variations are outlined.

Published
2018

41. Antiproliferative and Pro-apoptotic Activities of Tournefortia mutabilis vent. Leaves on the Human Breast Adenocarcinoma Cell Line (MCF-7).

Author

Mora-Guzmán Z, Bernardo Flores-Cotera L, Pérez-Campos E, López-Marure R, Soto-Castro D, Alonso Masso-Rojas F, Paéz Arenas A, Zenteno E, Martinez-Cruz M, Pérez-Campos Mayoral L, Hernández-Huerta MT, and Pina-Canseco MDS

Abstract

Background: Breast cancer is the most common cancer among women worldwide, impacting not only the patients but also their families and communities. Tournefortia mutabilis vent. is a plant endemic to Mexico, traditionally used in Zapotec medicine for the treatment of cancer., Objectives: This study aims to evaluate the effects of the chloroformic extract of T. mutabilis vent. leaves on cell proliferation and cell death in MCF-7 cells., Methods: The effect of the extract on MCF-7 cell proliferation was measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and crystal violet staining. Apoptosis was evaluated through fluorescein diacetate/propidium iodide staining and caspase-3, -6, and -9 activity assays., Results: The half-maximal inhibitory concentration (IC50) of the T. mutabilis vent. extract on MCF-7 cell proliferation at 48 hours and 72 hours after treatment was 86.4 µg/mL and 2.74 µg/mL, respectively. We observed that the extract and its semi-purified fractions induced cell death through the activation of caspases 3, -6, and -9., Conclusions: Tournefortia mutabilis vent. is a potential source of compounds with antiproliferative and pro-apoptotic activities on the MCF-7 cell line, primarily through the intrinsic pathways of apoptosis., Competing Interests: The authors declare no conflict of interest., (Copyright © 2024, Mora-Guzmán et al.)

Published
2024
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