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Cardiac angiosarcomas are rare malignant neoplasms with an aggressive clinical course. These are characterized by the absence of specific clinical findings, rapid growth with frequent metastasis at the time of diagnosis, correlated with poor prognosis, and reduced response to treatment. But with early diagnosis, more possibilities for treatment and survival can be provided. We report the case of a young woman diagnosed with right atrial angiosarcoma locally advanced with bone metastases detected by 18F-FDG PET/CT, which revealed distant disease extent at diagnosis, consequently, chemotherapy was started.

[EN] Team work is a competency that is actively being developed in educational institutions worlwide due to the high demand for citizens that are capable to work in teams or collaboratively. Educational institutions now have the challenge to educate and prepare students for the professional arena, where teamwork skills are essential.With the purpose to face this challenge educational institutions have, this research develops a process of authentic collaborative assessment through two main actions: 1) the implementation of a training program for students on the main principles of teamwork, and 2) the validation and piloting of a rubric to assess the process of university students’ collaboration. The study takes the assessment of 96 university students from different faculties and the data is analyzed with the software R. Results confirm the validity of the assessment tool, namely, the rubric that assesses the process of teamwork. Thus, this is a valuable tool to be used across all the faculties at the university. The study suggests using the rubric in different educational scenarios., [ES] El desarrollo de la competencia trabajo en equipo está siendo, cada vez más, un reto que las instituciones educativas plantean a la vista de la necesidad de formar a nuestros estudiantes y futuros profesionales, como ciudadanos capaces de adaptarse a los nuevos tiempos donde el trabajo en equipo o colaborativo es indispensable. Con el fin de dar respuesta a este reto, la presente investigación desarrolla un proceso de evaluación colaborativa auténtica en dos acciones principales 1) la formación de estudiantes en los principios de la competencia trabajo en equipo, y 2) la validación y pilotaje de una rúbrica de evaluación del proceso de trabajo colaborativo entre estudiantes universitarios. Se evalúan a 96 estudiantes universitarios de varios grados universitarios de distintas áreas y los datos obtenidos se analizan con el programa estadístico R. Los resultados constatan la validez y fiabilidad de la rúbrica para evaluar el proceso de trabajo en equipo, haciendo de ella, una herramienta idónea para ser utilizada de forma transversal en distintos grados universitarios. Este estudio plantea el potencial de utilizar esta herramienta en distintos escenarios educativos.

Hodgkin lymphoma (HL) is a type of blood cancer that generally originates in the lymph nodes and can spread within the lymphatic system. HL is highly curable and treated usually by chemotherapy following the ABVD (Adrymacin, Bleomycin, Vinblastine and Dacarbazine) regime. The evaluation of the response to the treatment of the patients is performed by the visual analysis of interim and end-of-treatment 18Ffluorodeoxyglucose (FDG) positron emission tomography (PET) images. The Deauville five-point scale is the internationally recommended tool to assess patient response. However, this scale is based on a visual analysis of PET-FDG images. Semiquantitative scales, called rPET and qPET that are based on the Standardized Uptake Value (SUV), have previously been proposed for a more objective classification of the cases. A graphical user interface is developed to manually select the lesions in PET images, process the images and automatically calculate the Deauville score based on the rPET and qPET scales. The algorithm is validated by analysing 9 cases of patients diagnosed with HL. The obtained Deauville scores are compared to the evaluation of the images by two physicians specialized in nuclear medicine. In 94.44% and 100% of the cases that are classified with the rPET and qPET scales, respectively, the result matches the visual analysis. The results obtained with both parameters could potentially indicate their viability in assessing the response to treatment in HL patients.

programs in the Matlab environment will be presented. Firstly, it will be demostrated the validity of this method to analyse waveguides and resonant cavities of various geometries and loaded with different media. This work reviews and compares different methods of solving electromagnetic problems by means of the FDM. The plan of this project can be specified in the following points: • Go over the concepts of Maxwell’s equations. • Implementation of FDM in one and two dimensions using Matlab environment. • Verification of the algorithms for a few structrures ( field distributions, resonant frequencies, cutoff frequencies, dispersion characteristics, etc ). • Analysis of possibilities of acceleration of the method in some special courses. Objectives: • Both understanding electromagnetic phenomenon in microwave and optical structures due to direct solution of Maxwell (in FDM). • Full acces to all variables and procedures. • Possibility of arbitrary modifications of the method (dedicated software can be faster and more accurate than the commercial one). Escuela Técnica Superior de Ingeniería de Telecomunicación Universidad Politécnica de Cartagena

Current methods for biomonitoring marine environments are aggressive, costly and time-consuming. DNA barcoding and metabarcoding offers a more accurate solution to this framework, but for this to be implemented, reliable reference sequences need to be available. The present study aimed to complete the reference database for metabarcoding studies. From an original list of 141 marine fish individuals, a total of 50 fish species were barcoded by PCR amplification of the 12s rRNA gene and sanger sequencing. A genetic analysis was additionally performed. Sequences are submitted to public access. Overall, DNA barcoding has shown to be a means by which marine resources could be surveyed without causing any negative impact. Ciencias del Mar

El objetivo principal del presente Trabajo Fin de Grado es realizar una revisión bibliográfica sobre las distintas metodologías de extracción de microplásticos en tractos gastrointestinales de Scyliorhinus canicula y sobre cuáles podrían utilizarse con esta especie en un futuro. Ciencias del Mar

Actualmente, la contaminación marina constituye uno de los principales problemas ambientales, que afecta particularmente a la calidad ambiental de un importante número de hábitats y especies. Debido a ello, surge la necesidad de cuantificar los contaminantes presentes en el medio y medir sus efectos en la biota. En este sentido, existen biomarcadores de contaminación que pueden utilizarse en diferentes especies y que permiten relacionar la presencia de un determinado contaminante con su efecto sobre el organismo. En el presente trabajo se ha realizado una revisión bibliográfica de los biomarcadores que se utilizan actualmente en diferentes especies de origen marino y, concretamente en Scyliorhinus canicula . Para ello se consultaron diferentes buscadores y bases de datos entre marzo y mayo de 2019. Los principales biomarcadores utilizados se clasifican en: biomarcadores de estrés oxidativo (como superóxido dismutasa, catalasa o glutatión peroxidasa) , de compuestos orgánicos (como ethoxyresorufin O-deethylase o glutathione-S-transferase) y de metales (como las metalotioneínas o enzyme delta-aminolevulinic acid dehydratase). Éstos se han aplicado en especies de diferentes grupos zoológicos, como teleósteos, moluscos, elasmobranquios, crustáceos, reptiles y mamíferos marinos, anélidos y equinodermos. Los más utilizados, hasta el momento, en Scyliorhinus canicula son EROD, GST, CAT y MT. La producción científica en este campo se ha concentrado en los últimos 4 años, con un importante aumento de las publicaciones en 2018. Esto, junto a los pocos estudios encontrados en Scyliorhinus canicula , pone de manifiesto la oportunidad que supone el estudio de biomarcadores, concretamente de metales, en esta especie Currently, marine pollution is one of the main environmental problems, which particularly affects the environmental quality of a significant number of habitats and species. Due to this, there is a need to quantify the contaminants present in the environment and measure their effects on the biota. In this sense, there are biomarkers of contamination that can be used in different species and that allows us to relate the presence of a certain contaminant with its effect on the organism. In the present work a bibliographic review of the biomarkers that are currently used in different species of marine origin and, specifically in Scyliorhinus canicula , has been carried out. For this, different search engines and databases were consulted between March and May of 2019. The most used biomarkers are classified as: biomarkers of oxidative stress (such as superoxide dismutase, catalase or glutathione peroxidase), organic compounds (such as ethoxyresorufin O-deethylase or glutathione-S-transferase) and metals (such as metallothioneins or enzyme delta-aminolevulinic acid dehydratase). These have been applied in species of different zoological groups, such as teleosts, mollusks, elasmobranchs, crustaceans, reptiles and marine mammals, annelids and echinoderms. The most used, so far, in Scyliorhinus canicula are EROD, GST, CAT and MT. The scientific production in this field has been concentrated in the last 4 years, with a significant increase in publications in 2018. This, together with the few studies found in Scyliorhinus canicula , highlights the opportunity involved in the study of biomarkers, specifically of metals, in this species. Ciencias del Mar