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4. DNA methylation-based classification of sinonasal tumors

Author

Jurmeister, Philipp, Glöß, Stefanie, Roller, Renée, Leitheiser, Maximilian, Schmid, Simone, Mochmann, Liliana H., Payá Capilla, Emma, Fritz, Rebecca, Dittmayer, Carsten, Friedrich, Corinna, Thieme, Anne, Keyl, Philipp, Jarosch, Armin, Schallenberg, Simon, Bläker, Hendrik, Hoffmann, Inga, Vollbrecht, Claudia, Lehmann, Annika, Hummel, Michael, Heim, Daniel, Haji, Mohamed, Harter, Patrick, Englert, Benjamin, Frank, Stephan, Hench, Jürgen, Paulus, Werner, Hasselblatt, Martin, Hartmann, Wolfgang, Dohmen, Hildegard, Keber, Ursula, Jank, Paul, Denkert, Carsten, Stadelmann, Christine, Bremmer, Felix, Richter, Annika, Wefers, Annika, Ribbat-Idel, Julika, Perner, Sven, Idel, Christian, Chiariotti, Lorenzo, Della Monica, Rosa, Marinelli, Alfredo, Schüller, Ulrich, Bockmayr, Michael, Liu, Jacklyn, Lund, Valerie J., Forster, Martin, Lechner, Matt, Lorenzo-Guerra, Sara L., Hermsen, Mario, Johann, Pascal D., Agaimy, Abbas, Seegerer, Philipp, Koch, Arend, Heppner, Frank, Pfister, Stefan M., Jones, David T. W., Sill, Martin, von Deimling, Andreas, Snuderl, Matija, Müller, Klaus-Robert, Forgó, Erna, Howitt, Brooke E., Mertins, Philipp, Klauschen, Frederick, and Capper, David

Published
2022
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5. The European Network for Sinonasal Cancer Research (EUSICA) – A pan-European initiative targeting a group of orphan tumours

Author

Hermsen, Mario, primary, Bossi, Paolo, additional, Capper, David, additional, Fleming, Jason, additional, Haybaeck, Johannes, additional, Martinez-Balibrea, Eva, additional, Nuyts, Sandra, additional, Skalova, Alena, additional, Thomson, David, additional, Trama, Annalisa, additional, Turri-Zanoni, Mario, additional, Verillaud, Benjamin, additional, Woods, Robbie, additional, von Buchwald, Christian, additional, and Lechner, Matt, additional

Published
2024
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7. Whole exome sequencing of human papillomavirus-related multiphenotypic sinonasal carcinoma: a case report.

Author

Cubides-Córdoba, María Camila, Sánchez-Fernández, Paula, Mendoza-Pacas, Guillermo E., Cabal, Virginia N., García-Marín, Rocío, Lucila Lorenzo-Guerra, Sara, García-Velasco, Fabián, Hermsen, Mario A., and Luis Llorente, José

Subjects
SOMATIC mutation, GENE expression, NUCLEIC acid hybridization, HUMAN papillomavirus, DRUG target, ADENOID cystic carcinoma
Abstract

Human Papillomavirus (HPV) related Multiphenotypic Sinonasal Carcinoma (HMSC) is a rare tumor with features of both atypical squamous cell and adenoid cystic carcinoma, making diagnosis challenging. Approximately 80% of HMSC cases carries HPV type 33 followed by type 35. We present a patient with HMSC. Pathological classification was aided by immunohistochemistry (IHC). The presence of HPV-DNA was tested using PCR and HPV E6/E7 expression by RNA in situ hybridization (RNA ISH). Whole exome sequencing (WES) was used to identify somatic gene mutations and copy number alterations. A 55-year-old male presented with an HMSC in the right nostril. Histological examination showed a solid basaloid subtype with mucinous spaces and ductal structures. IHC showed positive staining for SOX-10, SMA, p40, p63, PanCK, CK8 and MYB. Diffuse positive staining for p16 was observed and PCR and RNA ISH indicated the presence of HPV type 35. The patient was treated with endoscopic surgery and radiotherapy and is currently alive and recurrence-free after 16 months of followup. WES revealed 38 somatic sequence variants and several chromosomal regions with copy number alterations, including a copy number gain at 6q23 where MYB is located. EP300, ZNF22, ZNF609 and LRIG3 are some of the genes whose mutations were indicated as probably pathogenic. We did not find mutations predictive for drug response according to the ESMO Scale for Clinical Actionability of Molecular Targets database. This is the first report of WES analysis of an HMSC, in this case associated with HPV type 35. The detected mutation in EP300 and the overexpression of MYB may serve as molecular targets for personalized therapy. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Next‐generation sequencing reveals remarkable genetic stability in primary and corresponding recurrent intestinal‐type sinonasal adenocarcinoma.

Author

Riobello, Cristina, Sánchez‐Fernández, Paula, Córdoba, María Camila Cubides, González‐Gutiérrez, Maripaz, Vivanco, Blanca, Cabal, Virginia N., Fernández, Laura Suárez, García‐Marín, Rocío, Codina‐Martínez, Helena, Lorenzo‐Guerra, Sara Lucila, López, Fernando, Hermsen, Mario A., and Llorente, José Luis

Subjects
SECONDARY primary cancer, NUCLEOTIDE sequencing, SOMATIC mutation, PARANASAL sinuses, ADENOCARCINOMA
Abstract

Background: Recurrent intestinal‐type sinonasal adenocarcinoma (ITAC) can occur several years after primary treatment and with different histology. We aimed to clarify if such recurrences could be second primary tumors and to identify actionable mutations as targets for personalized treatment of recurrent ITAC. Methods: Twelve pairs of primary and recurrent ITAC were histologically examined and analyzed by next‐generation sequencing. Results: Histological differences between primary and recurrent tumor pairs were observed in five cases. Frequent mutations included TP53, APC, TSC2, ATM, EPHA2, BRCA2, LRP1B, KRAS, and KMT2B. There was 86% concordance of somatic mutations between the tumor pairs, while four cases carried additional mutations in the recurrence. Conclusions: We found all cases to be clonal recurrences and not second primary tumors. Moreover, tumor pairs showed a remarkable genomic stability, suggesting that personalized treatment of a recurrence may be based on actionable molecular genetic targets observed in the primary tumor. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Experimental Models of Sinonasal Tumors for Preclinical Testing of Candidate Targeted Therapies

Author

Codina-Martínez, Helena, primary, Lorenzo-Guerra, Sara Lucila, additional, Cabal, Virginia N., additional, García-Marín, Rocío, additional, Riobello, Cristina, additional, Suárez-Fernández, Laura, additional, Vivanco, Blanca, additional, Blanco-Lorenzo, Verónica, additional, López, Fernando, additional, Sánchez-Fernández, Paula, additional, Hermsen, Mario A., additional, and Llorente, José Luis, additional

Published
2023
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15. O180 / #616 - RADGESS: PRELIMINARY RESULTS OF THE IN SILICO STUDY FOR RADIORESISTANCE GENOMIC SIGNATURES IN SINONASAL CANCERS EXPERIMENTAL MODELS AFTER PARTICLE THERAPY

Author

Giorgia, Fulgini, Charalampopoulou, Alexandra, Molinelli, Silvia, Pullia, Marco, Codina-Martinez, Helena, Lenoci, Deborah, Lucchetta, Marta, Takahashi, Yoko, Hanna, Hehab, Locati, Laura Deborah, Ivaldi, Giovanni B, De Cecco, Loris, Hermsen, Mario, Facoetti, Angelica, and Orlandi, Ester

Published
2024
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16. Sox2 and βIII-Tubulin as Biomarkers of Drug Resistance in Poorly Differentiated Sinonasal Carcinomas

Author

López, Luis, primary, Fernández-Vañes, Laura, additional, Cabal, Virginia N., additional, García-Marín, Rocío, additional, Suárez-Fernández, Laura, additional, Codina-Martínez, Helena, additional, Lorenzo-Guerra, Sara L., additional, Vivanco, Blanca, additional, Blanco-Lorenzo, Verónica, additional, Llorente, José L., additional, López, Fernando, additional, and Hermsen, Mario A., additional

Published
2023
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17. Signaling Pathways mTOR and ERK as Therapeutic Targets in Sinonasal Intestinal-Type Adenocarcinoma

Author

Codina-Martínez, Helena, primary, Lorenzo-Guerra, Sara Lucila, additional, Cabal, Virginia N., additional, García-Marín, Rocío, additional, Suárez-Fernández, Laura, additional, Vivanco, Blanca, additional, Sánchez-Fernández, Paula, additional, López, Fernando, additional, Llorente, José Luis, additional, and Hermsen, Mario A., additional

Published
2023
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18. Molecular Pathology of Sinonasal Tumors

Author

Hermsen, Mario A., primary, Riobello, C., additional, García-Marín, R., additional, Cabal, V. N., additional, Suárez-Fernández, L., additional, López, F., additional, and Llorente, J. L., additional

Published
2019
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22. Characterization of a Preclinical In Vitro Model Derived from a SMARCA4-Mutated Sinonasal Teratocarcinosarcoma.

Author

Lorenzo-Guerra, Sara Lucila, Codina-Martínez, Helena, Suárez-Fernández, Laura, Cabal, Virginia N., García-Marín, Rocío, Riobello, Cristina, Vivanco, Blanca, Blanco-Lorenzo, Verónica, Sánchez-Fernández, Paula, López, Fernando, Llorente, Jóse Luis, and Hermsen, Mario A.

Subjects
SOMATIC mutation, PARANASAL sinuses, CYCLIN-dependent kinase inhibitors, ANIMAL models in research, NEUROENDOCRINE cells
Abstract

Sinonasal teratocarcinosarcoma (TCS) is a rare tumor that displays a variable histology with admixtures of epithelial, mesenchymal, neuroendocrine and germ cell elements. Facing a very poor prognosis, patients with TCS are in need of new options for treatment. Recently identified recurrent mutations in SMARCA4 may serve as target for modern therapies with EZH1/2 and CDK4/6 inhibitors. Here, we present the first in vitro cell line TCS627, established from a previously untreated primary TCS originating in the ethmoid sinus with invasion into the brain. The cultured cells expressed immunohistochemical markers, indicating differentiation of epithelial, neuroepithelial, sarcomatous and teratomatous components. Whole-exome sequencing revealed 99 somatic mutations including SMARCA4, ARID2, TET2, CDKN2A, WNT7A, NOTCH3 and STAG2, all present both in the primary tumor and in the cell line. Focusing on mutated SMARCA4 as the therapeutic target, growth inhibition assays showed a strong response to the CDK4/6 inhibitor palbociclib, but much less to the EZH1/2 inhibitor valemetostat. In conclusion, cell line TCS627 carries both histologic and genetic features characteristic of TCS and is a valuable model for both basic research and preclinical testing of new therapeutic options for treatment of TCS patients. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Supplementary Data from Amplicon Mapping and Expression Profiling Identify the Fas-Associated Death Domain Gene as a New Driver in the 11q13.3 Amplicon in Laryngeal/Pharyngeal Cancer

Author

Gibcus, Johan H., primary, Menkema, Lorian, primary, Mastik, Mirjam F., primary, Hermsen, Mario A., primary, de Bock, Geertruida H., primary, van Velthuysen, Marie-Louise F., primary, Takes, Robert P., primary, Kok, Klaas, primary, Álvarez Marcos, Cesar A., primary, van der Laan, Bernard F.A.M., primary, van den Brekel, Michiel W.M., primary, Langendijk, Johannes A., primary, Kluin, Philip M., primary, van der Wal, Jacqueline E., primary, and Schuuring, Ed, primary

Published
2023
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24. Supplementary Table 2 from Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out

Author

Neumann, Hartmut P.H., primary, Erlic, Zoran, primary, Boedeker, Carsten C., primary, Rybicki, Lisa A., primary, Robledo, Mercedes, primary, Hermsen, Mario, primary, Schiavi, Francesca, primary, Falcioni, Maurizio, primary, Kwok, Pingling, primary, Bauters, Catherine, primary, Lampe, Karen, primary, Fischer, Markus, primary, Edelman, Emily, primary, Benn, Diana E., primary, Robinson, Bruce G., primary, Wiegand, Stefanie, primary, Rasp, Gerd, primary, Stuck, Boris A., primary, Hoffmann, Michael M., primary, Sullivan, Maren, primary, Sevilla, Maria A., primary, Weiss, Marjan M., primary, Peczkowska, Mariola, primary, Kubaszek, Agata, primary, Pigny, Pascal, primary, Ward, Robyn L., primary, Learoyd, Diana, primary, Croxson, Michael, primary, Zabolotny, Dmitry, primary, Yaremchuk, Svetlana, primary, Draf, Wolfgang, primary, Muresan, Mihaela, primary, Lorenz, Robert R., primary, Knipping, Stephan, primary, Strohm, Michael, primary, Dyckhoff, Gerhard, primary, Matthias, Christoph, primary, Reisch, Nicole, primary, Preuss, Simon F., primary, Eβer, Dirk, primary, Walter, Martin A., primary, Kaftan, Holger, primary, Stöver, Timo, primary, Fottner, Christian, primary, Gorgulla, Harald, primary, Malekpour, Mahdi, primary, Zarandy, Masoud Motasaddi, primary, Schipper, Jörg, primary, Brase, Christoph, primary, Glien, Alexander, primary, Kühnemund, Matthias, primary, Koscielny, Sven, primary, Schwerdtfeger, Peter, primary, Välimäki, Matti, primary, Szyfter, Witold, primary, Finckh, Ulrich, primary, Zerres, Klaus, primary, Cascon, Alberto, primary, Opocher, Giuseppe, primary, Ridder, Gerd J., primary, Januszewicz, Andrzej, primary, Suarez, Carlos, primary, and Eng, Charis, primary

Published
2023
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25. Supplementary Table 1 from High-Frequency Targetable EGFR Mutations in Sinonasal Squamous Cell Carcinomas Arising from Inverted Sinonasal Papilloma

Author

Udager, Aaron M., primary, Rolland, Delphine C.M., primary, McHugh, Jonathan B., primary, Betz, Bryan L., primary, Murga-Zamalloa, Carlos, primary, Carey, Thomas E., primary, Marentette, Lawrence J., primary, Hermsen, Mario A., primary, DuRoss, Kathleen E., primary, Lim, Megan S., primary, Elenitoba-Johnson, Kojo S.J., primary, and Brown, Noah A., primary

Published
2023
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26. Other Supporting Colleagues from Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out

Author

Neumann, Hartmut P.H., primary, Erlic, Zoran, primary, Boedeker, Carsten C., primary, Rybicki, Lisa A., primary, Robledo, Mercedes, primary, Hermsen, Mario, primary, Schiavi, Francesca, primary, Falcioni, Maurizio, primary, Kwok, Pingling, primary, Bauters, Catherine, primary, Lampe, Karen, primary, Fischer, Markus, primary, Edelman, Emily, primary, Benn, Diana E., primary, Robinson, Bruce G., primary, Wiegand, Stefanie, primary, Rasp, Gerd, primary, Stuck, Boris A., primary, Hoffmann, Michael M., primary, Sullivan, Maren, primary, Sevilla, Maria A., primary, Weiss, Marjan M., primary, Peczkowska, Mariola, primary, Kubaszek, Agata, primary, Pigny, Pascal, primary, Ward, Robyn L., primary, Learoyd, Diana, primary, Croxson, Michael, primary, Zabolotny, Dmitry, primary, Yaremchuk, Svetlana, primary, Draf, Wolfgang, primary, Muresan, Mihaela, primary, Lorenz, Robert R., primary, Knipping, Stephan, primary, Strohm, Michael, primary, Dyckhoff, Gerhard, primary, Matthias, Christoph, primary, Reisch, Nicole, primary, Preuss, Simon F., primary, Eβer, Dirk, primary, Walter, Martin A., primary, Kaftan, Holger, primary, Stöver, Timo, primary, Fottner, Christian, primary, Gorgulla, Harald, primary, Malekpour, Mahdi, primary, Zarandy, Masoud Motasaddi, primary, Schipper, Jörg, primary, Brase, Christoph, primary, Glien, Alexander, primary, Kühnemund, Matthias, primary, Koscielny, Sven, primary, Schwerdtfeger, Peter, primary, Välimäki, Matti, primary, Szyfter, Witold, primary, Finckh, Ulrich, primary, Zerres, Klaus, primary, Cascon, Alberto, primary, Opocher, Giuseppe, primary, Ridder, Gerd J., primary, Januszewicz, Andrzej, primary, Suarez, Carlos, primary, and Eng, Charis, primary

Published
2023
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27. Supplementary Table 1 from Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out

Author

Neumann, Hartmut P.H., primary, Erlic, Zoran, primary, Boedeker, Carsten C., primary, Rybicki, Lisa A., primary, Robledo, Mercedes, primary, Hermsen, Mario, primary, Schiavi, Francesca, primary, Falcioni, Maurizio, primary, Kwok, Pingling, primary, Bauters, Catherine, primary, Lampe, Karen, primary, Fischer, Markus, primary, Edelman, Emily, primary, Benn, Diana E., primary, Robinson, Bruce G., primary, Wiegand, Stefanie, primary, Rasp, Gerd, primary, Stuck, Boris A., primary, Hoffmann, Michael M., primary, Sullivan, Maren, primary, Sevilla, Maria A., primary, Weiss, Marjan M., primary, Peczkowska, Mariola, primary, Kubaszek, Agata, primary, Pigny, Pascal, primary, Ward, Robyn L., primary, Learoyd, Diana, primary, Croxson, Michael, primary, Zabolotny, Dmitry, primary, Yaremchuk, Svetlana, primary, Draf, Wolfgang, primary, Muresan, Mihaela, primary, Lorenz, Robert R., primary, Knipping, Stephan, primary, Strohm, Michael, primary, Dyckhoff, Gerhard, primary, Matthias, Christoph, primary, Reisch, Nicole, primary, Preuss, Simon F., primary, Eβer, Dirk, primary, Walter, Martin A., primary, Kaftan, Holger, primary, Stöver, Timo, primary, Fottner, Christian, primary, Gorgulla, Harald, primary, Malekpour, Mahdi, primary, Zarandy, Masoud Motasaddi, primary, Schipper, Jörg, primary, Brase, Christoph, primary, Glien, Alexander, primary, Kühnemund, Matthias, primary, Koscielny, Sven, primary, Schwerdtfeger, Peter, primary, Välimäki, Matti, primary, Szyfter, Witold, primary, Finckh, Ulrich, primary, Zerres, Klaus, primary, Cascon, Alberto, primary, Opocher, Giuseppe, primary, Ridder, Gerd J., primary, Januszewicz, Andrzej, primary, Suarez, Carlos, primary, and Eng, Charis, primary

Published
2023
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28. Data from High-Frequency Targetable EGFR Mutations in Sinonasal Squamous Cell Carcinomas Arising from Inverted Sinonasal Papilloma

Author

Udager, Aaron M., primary, Rolland, Delphine C.M., primary, McHugh, Jonathan B., primary, Betz, Bryan L., primary, Murga-Zamalloa, Carlos, primary, Carey, Thomas E., primary, Marentette, Lawrence J., primary, Hermsen, Mario A., primary, DuRoss, Kathleen E., primary, Lim, Megan S., primary, Elenitoba-Johnson, Kojo S.J., primary, and Brown, Noah A., primary

Published
2023
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29. Data from Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out

Author

Neumann, Hartmut P.H., primary, Erlic, Zoran, primary, Boedeker, Carsten C., primary, Rybicki, Lisa A., primary, Robledo, Mercedes, primary, Hermsen, Mario, primary, Schiavi, Francesca, primary, Falcioni, Maurizio, primary, Kwok, Pingling, primary, Bauters, Catherine, primary, Lampe, Karen, primary, Fischer, Markus, primary, Edelman, Emily, primary, Benn, Diana E., primary, Robinson, Bruce G., primary, Wiegand, Stefanie, primary, Rasp, Gerd, primary, Stuck, Boris A., primary, Hoffmann, Michael M., primary, Sullivan, Maren, primary, Sevilla, Maria A., primary, Weiss, Marjan M., primary, Peczkowska, Mariola, primary, Kubaszek, Agata, primary, Pigny, Pascal, primary, Ward, Robyn L., primary, Learoyd, Diana, primary, Croxson, Michael, primary, Zabolotny, Dmitry, primary, Yaremchuk, Svetlana, primary, Draf, Wolfgang, primary, Muresan, Mihaela, primary, Lorenz, Robert R., primary, Knipping, Stephan, primary, Strohm, Michael, primary, Dyckhoff, Gerhard, primary, Matthias, Christoph, primary, Reisch, Nicole, primary, Preuss, Simon F., primary, Eβer, Dirk, primary, Walter, Martin A., primary, Kaftan, Holger, primary, Stöver, Timo, primary, Fottner, Christian, primary, Gorgulla, Harald, primary, Malekpour, Mahdi, primary, Zarandy, Masoud Motasaddi, primary, Schipper, Jörg, primary, Brase, Christoph, primary, Glien, Alexander, primary, Kühnemund, Matthias, primary, Koscielny, Sven, primary, Schwerdtfeger, Peter, primary, Välimäki, Matti, primary, Szyfter, Witold, primary, Finckh, Ulrich, primary, Zerres, Klaus, primary, Cascon, Alberto, primary, Opocher, Giuseppe, primary, Ridder, Gerd J., primary, Januszewicz, Andrzej, primary, Suarez, Carlos, primary, and Eng, Charis, primary

Published
2023
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30. Supplementary Table 2 from High-Frequency Targetable EGFR Mutations in Sinonasal Squamous Cell Carcinomas Arising from Inverted Sinonasal Papilloma

Author

Udager, Aaron M., primary, Rolland, Delphine C.M., primary, McHugh, Jonathan B., primary, Betz, Bryan L., primary, Murga-Zamalloa, Carlos, primary, Carey, Thomas E., primary, Marentette, Lawrence J., primary, Hermsen, Mario A., primary, DuRoss, Kathleen E., primary, Lim, Megan S., primary, Elenitoba-Johnson, Kojo S.J., primary, and Brown, Noah A., primary

Published
2023
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31. Supplementary Tables 3-6 from High-Frequency Targetable EGFR Mutations in Sinonasal Squamous Cell Carcinomas Arising from Inverted Sinonasal Papilloma

Author

Udager, Aaron M., primary, Rolland, Delphine C.M., primary, McHugh, Jonathan B., primary, Betz, Bryan L., primary, Murga-Zamalloa, Carlos, primary, Carey, Thomas E., primary, Marentette, Lawrence J., primary, Hermsen, Mario A., primary, DuRoss, Kathleen E., primary, Lim, Megan S., primary, Elenitoba-Johnson, Kojo S.J., primary, and Brown, Noah A., primary

Published
2023
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32. Supplementary Table 1 Legends and References from Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out

Author

Neumann, Hartmut P.H., primary, Erlic, Zoran, primary, Boedeker, Carsten C., primary, Rybicki, Lisa A., primary, Robledo, Mercedes, primary, Hermsen, Mario, primary, Schiavi, Francesca, primary, Falcioni, Maurizio, primary, Kwok, Pingling, primary, Bauters, Catherine, primary, Lampe, Karen, primary, Fischer, Markus, primary, Edelman, Emily, primary, Benn, Diana E., primary, Robinson, Bruce G., primary, Wiegand, Stefanie, primary, Rasp, Gerd, primary, Stuck, Boris A., primary, Hoffmann, Michael M., primary, Sullivan, Maren, primary, Sevilla, Maria A., primary, Weiss, Marjan M., primary, Peczkowska, Mariola, primary, Kubaszek, Agata, primary, Pigny, Pascal, primary, Ward, Robyn L., primary, Learoyd, Diana, primary, Croxson, Michael, primary, Zabolotny, Dmitry, primary, Yaremchuk, Svetlana, primary, Draf, Wolfgang, primary, Muresan, Mihaela, primary, Lorenz, Robert R., primary, Knipping, Stephan, primary, Strohm, Michael, primary, Dyckhoff, Gerhard, primary, Matthias, Christoph, primary, Reisch, Nicole, primary, Preuss, Simon F., primary, Eβer, Dirk, primary, Walter, Martin A., primary, Kaftan, Holger, primary, Stöver, Timo, primary, Fottner, Christian, primary, Gorgulla, Harald, primary, Malekpour, Mahdi, primary, Zarandy, Masoud Motasaddi, primary, Schipper, Jörg, primary, Brase, Christoph, primary, Glien, Alexander, primary, Kühnemund, Matthias, primary, Koscielny, Sven, primary, Schwerdtfeger, Peter, primary, Välimäki, Matti, primary, Szyfter, Witold, primary, Finckh, Ulrich, primary, Zerres, Klaus, primary, Cascon, Alberto, primary, Opocher, Giuseppe, primary, Ridder, Gerd J., primary, Januszewicz, Andrzej, primary, Suarez, Carlos, primary, and Eng, Charis, primary

Published
2023
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44. Biomarkers for Immunotherapy in Poorly Differentiated Sinonasal Tumors

Author

Villanueva-Fernández, Eva, primary, Hermsen, Mario A., additional, Suárez-Fernández, Laura, additional, Vivanco, Blanca, additional, Franchi, Alessandro, additional, García-Marín, Rocío, additional, Cabal, Virginia N., additional, Codina-Martínez, Helena, additional, Lorenzo-Guerra, Sara Lucila, additional, Llorente, José L., additional, and López, Fernando, additional

Published
2022
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