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17 results on '"Henry, Jean-Marc"'

1. Metal-Catalyzed C–N Bond Forming Reaction Selection and Process Development for the Manufacture of AZD7594

Author

Aydin, Gulsevim, primary, Ball, Matthew, additional, Bishop, Thomas George, additional, Burns, Matthew, additional, Campbell, Andrew D., additional, Cox, Robert J., additional, Dai, Kuangchu, additional, Dave, David, additional, Fisk, Heidi, additional, Hamilton, Laura, additional, Heffernan, Claire, additional, Henry, Jean-Marc, additional, Holman, Stephen W., additional, Jones, Martin F., additional, Noonan, Gary, additional, Patel, Bharti, additional, Streather, David, additional, and Tomasi, Simone, additional

Published
2024
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9. Combining Postcards, Crisis Cards, and Telephone Contact Into a Decision-Making Algorithm to Reduce Suicide Reattempt

Author

Vaiva, Guillaume, Berrouiguet, Sofian, Walter, Michel, Courtet, Philippe, Ducrocq, François, Jardon, Vincent, Larsen, Mark, Cailhol, Lionel, Godesense, Carole, Couturier, Christophe, Mathur, Anjali, Lagree, Virginie, Pichene, Catherine, Travers, David, Lemogne, Cédric, Henry, Jean Marc, Jover, Frederic, Chastang, Francoise, Prudhomme, Olivier, Lestavel, Philippe, Gignac, Catherine Thevenon, Duhem, Stéphane, Demarty, Anne Laure, Mesmeur, Catherine, Bellivier, Frank, Labreuche, Julien, Duhamel, Alain, Goldstein, Patrick, Service de Psychiatrie [CHRU Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Hôpital Michel Fontan 1, Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193 (SCALab), Université de Lille-Centre National de la Recherche Scientifique (CNRS), CHRU Brest - Psychiatrie Adulte (CHU - Brest- Psychiatrie), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Neuropsychiatrie : recherche épidémiologique et clinique (PSNREC), Université Montpellier 1 (UM1)-Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Samu du Nord–pôle de l’urgence [Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre hospitalier de Montauban, Centre Hospitalier de Roubaix, Centre Hospitalier de Dunkerque, CHU Toulouse [Toulouse], Centre hospitalier universitaire de Nantes (CHU Nantes), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Service de Psychiatrie [Rennes], Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-CHU Pontchaillou [Rennes], Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Institut de psychiatrie et neurosciences (U894 / UMS 1266), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital de la Conception [CHU - APHM] (LA CONCEPTION), Centre Hospitalier Universitaire de Nice (CHU Nice), Service de psychiatrie [CHU Caen], Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), Centre Hospitalier [Douai, Nord], Centre Hospitalier de Tourcoing, Centre d'Investigation Clinique - Innovation Technologique de Lille - CIC 1403 - CIC 9301 (CIC Lille), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Evaluation des technologies de santé et des pratiques médicales - ULR 2694 (METRICS), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Neuropsychiatrie : recherche épidémiologique et clinique, Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Hôpital de la Conception [CHU - APHM] (LA CONCEPTION ), CIC Lille, Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Santé publique : épidémiologie et qualité des soins-EA 2694 (CERIM), Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 (SCALab), Centre hospitalier de Montauban (CH Montauban), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Université de Rennes (UR)-CHU Pontchaillou [Rennes], and Centre de Psychiatrie et Neurosciences (U894)

Subjects
[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health
Abstract

International audience; BACKGROUND:There is growing evidence in the literature that brief contact interventions (BCIs) might be reliable suicide prevention strategies.OBJECTIVE:To assess the effectiveness of a decision-making algorithm for suicide prevention (ALGOS) combining existing BCIs in reducing suicide reattempts in patients discharged after a suicide attempt.METHODS:A randomized, multicenter, controlled, parallel trial was conducted in 23 hospitals. The study was conducted from January 26, 2010, to February 28, 2013. People who had made a suicide attempt were randomly assigned to either the intervention group (ALGOS) or the control group. The primary outcome was the rate of participants who reattempted suicide (fatal or not) within the 6-month study period.RESULTS:1,040 patients were recruited. After 6 months, 58 participants in the intervention group (12.8%) reattempted suicide compared with 77 (17.2%) in the control group. The difference between groups (4.4%; 95% CI, -0.7% to 9.0%) was not significant (complete-case analysis, P = .059).CONCLUSIONS:These results may help researchers better integrate BCIs into routine health care and provide new insights concerning personalized suicide prevention strategies.TRIAL REGISTRATION:ClinicalTrials.gov identifier: NCT01123174.

Published
2018
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10. Classification et catégories en psychiatrie: enjeux éthiques

Author

Cano, Nicole, Henry, Jean-Marc, Lagier, Frédérique, Ravix, Valery, Anthropologie bio-culturelle, Droit, Ethique et Santé (ADES), Aix Marseille Université (AMU)-EFS ALPES MEDITERRANEE-Centre National de la Recherche Scientifique (CNRS), Espace éthique méditerranéen, Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), N. Cano, J.-M. Henry, F. Lagier, V. Ravix, and C. Tappero

Subjects
ComputingMilieux_MISCELLANEOUS, [SDV.ETH]Life Sciences [q-bio]/Ethics
Abstract

National audience

Published
2016

11. Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C-H activation

Author

Latham, Jonathan, Henry, Jean-Marc, Sharif, Humera, Menon, Binuraj, Shepherd, Sarah, Greaney, Michael, and Micklefield, Jason

Subjects
Chemistry(all), Biochemistry, Genetics and Molecular Biology(all), Physics and Astronomy(all)
Abstract

Despite major recent advances in C-H activation, discrimination between two similar, unactivated C-H positions is beyond the scope of current chemocatalytic methods. Here we demonstrate that integration of regioselective halogenase enzymes with Pd-catalysed cross-coupling chemistry, in one-pot reactions, successfully addresses this problem for the indole heterocycle. The resultant 'chemobio-transformation' delivers a range of functionally diverse arylated products that are impossible to access using separate enzymatic or chemocatalytic C-H activation, under mild, aqueous conditions. This use of different biocatalysts to select different C-H positions contrasts with the prevailing substrate-control approach to the area, and presents opportunities for new pathways in C-H activation chemistry. The issues of enzyme and transition metal compatibility are overcome through membrane compartmentalization, with the optimized process requiring no intermediate work-up or purification steps.

Published
2016
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15. Arithmetic Operations on Self-Replicating Cellular Automata.

Author

Goos, G., Hartmanis, J., van Leeuwen, J., Floreano, Dario, Nicoud, Jean-Daniel, Mondada, Francesco, Carbonell, Jaime G., Siekmann, Jörg, Petraglio, Enrico, Henry, Jean-Marc, and Tempesti, Gianluca

Abstract

In this paper, we present a possible implementation of arithmetic functions (notably, addition and multiplication) using self-replicating cellular automata. The operations are performed by storing a dedicated program (sequence of states) on self-replicating loops, and letting the loops retrieve the operands, exchange data among themselves, and perform the calculations according to a set of rules. To determine the rules required for addition and multiplication, we exploited an existing algorithm for computation in the cellular automata environment and adapted it to exploit the features of self-replicating loops. This approach allowed us to study a variety of issues (synchronization, data exchange, etc.) related to the use of self-replicating machines for complex operations. [ABSTRACT FROM AUTHOR]

Published
1999
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16. Le « Trouble de l'identité de genre » dans la pratique clinique : de la catégorie au diagnostic

Author

Hérault, Laurence, Institut d'ethnologie méditerranéenne, européenne et comparative (IDEMEC), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Cano, Nicole, Henry, Jean-Marc, Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), and Hérault, Laurence

Subjects
[SHS.ANTHRO-SE] Humanities and Social Sciences/Social Anthropology and ethnology, [SHS.ANTHRO-SE]Humanities and Social Sciences/Social Anthropology and ethnology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2016

17. Combining Postcards, Crisis Cards, and Telephone Contact Into a Decision-Making Algorithm to Reduce Suicide Reattempt: A Randomized Clinical Trial of a Personalized Brief Contact Intervention.

Author

Vaiva G, Berrouiguet S, Walter M, Courtet P, Ducrocq F, Jardon V, Larsen ME, Cailhol L, Godesense C, Couturier C, Mathur A, Lagree V, Pichene C, Travers D, Lemogne C, Henry JM, Jover F, Chastang F, Prudhomme O, Lestavel P, Gignac CT, Duhem S, Demarty AL, Mesmeur C, Bellivier F, Labreuche J, Duhamel A, and Goldstein P

Subjects
Adolescent, Adult, Algorithms, Decision Making, Female, Humans, Male, Mental Disorders epidemiology, Middle Aged, Postcards as Topic, Single-Blind Method, Suicide, Attempted statistics & numerical data, Telephone, Time Factors, Young Adult, Psychotherapy, Brief methods, Reminder Systems, Suicide, Attempted prevention & control
Abstract

Background: There is growing evidence in the literature that brief contact interventions (BCIs) might be reliable suicide prevention strategies., Objective: To assess the effectiveness of a decision-making algorithm for suicide prevention (ALGOS) combining existing BCIs in reducing suicide reattempts in patients discharged after a suicide attempt., Methods: A randomized, multicenter, controlled, parallel trial was conducted in 23 hospitals. The study was conducted from January 26, 2010, to February 28, 2013. People who had made a suicide attempt were randomly assigned to either the intervention group (ALGOS) or the control group. The primary outcome was the rate of participants who reattempted suicide (fatal or not) within the 6-month study period., Results: 1,040 patients were recruited. After 6 months, 58 participants in the intervention group (12.8%) reattempted suicide compared with 77 (17.2%) in the control group. The difference between groups (4.4%; 95% CI, -0.7% to 9.0%) was not significant (complete-case analysis, P = .059)., Conclusions: These results may help researchers better integrate BCIs into routine health care and provide new insights concerning personalized suicide prevention strategies., Trial Registration: ClinicalTrials.gov identifier: NCT01123174., (© Copyright 2018 Physicians Postgraduate Press, Inc.)

Published
2018
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