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4. Intravitreal Aflibercept for Retinal Nonperfusion in Proliferative Diabetic Retinopathy: Outcomes from the Randomized RECOVERY Trial

Author

Wykoff, Charles C., Nittala, Muneeswar G., Zhou, Brenda, Fan, Wenying, Velaga, Swetha Bindu, Rusakevich, Alexander M., Lampen, Shaun I.R., Ip, Michael S., Sadda, SriniVas R., Ehlers, Justis P., Srivastava, Sunil K., Reese, Jamie L., Babiuch, Amy, Talcott, Katherine, Figueiredo, Natalia, Hach, Jenna, Ou, William C., Fish, Richard H., Benz, Matthew S., Chen, Eric, Kim, Rosa Y., Major, James C., Jr., O’Malley, Ronan E., Brown, David M., Shah, Ankoor R., Schefler, Amy C., Wong, Tien P., and Henry, Christopher R.

Published
2019
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5. MANAGEMENT OF LARGE FULL-THICKNESS MACULAR HOLES

Author

Richards, Kaitlyn, Kadakia, Ankit, Wykoff, Charles C., Major, James C., Wong, Tien P., Chen, Eric, Schefler, Amy C., Patel, Sagar B., Kim, Rosa Y., Henry, Christopher R., Fish, Richard H., Brown, David M., Benz, Matthew S., Pearce, William, and Shah, Ankoor R.

Abstract

Long-term closure rates of FTMH were examined for the ILM flap and ILM peel techniques based on the initial macular hole size. ILM flaps and peels both had comparable success rates at each FTMH size groups. A declining success rate was noted regardless of technique as the size increased.

Published
2024
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6. Retinal Tears

Author

Henry, Christopher R., Medina, Carlos A., editor, Townsend, Justin H., editor, and Singh, Arun D., editor

Published
2016
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9. Suprachoroidal CLS-TA with and without Systemic Corticosteroid and/or Steroid-Sparing Therapy: A Post-Hoc Analysis of the Phase 3 PEACHTREE Clinical Trial.

Author

Merrill, Pauline T., Henry, Christopher R., Nguyen, Quan Dong, Reddy, Ashvini, Kapik, Barry, and Ciulla, Thomas A.

Subjects
*OPTICAL coherence tomography, *CLINICAL trials, *MACULAR edema, *TRIAMCINOLONE acetonide, *IRIDOCYCLITIS, *CORTICOSTEROIDS
Abstract

To study the efficacy and safety of suprachoroidal CLS-TA (proprietary suspension of triamcinolone acetonide) in uveitic macular edema (UME) with and without concurrent systemic corticosteroid or steroid-sparing therapy (ST). Post hoc analysis of the PEACHTREE phase 3 randomized trial. Among UME patients receiving no ST, at week 24, mean BCVA change was +15.6 letters in 68 CLS-TA patients versus +4.9 letters in 49 sham-control patients (p <.001), while mean CST change was −169.8 µm versus −10.3 µm, respectively (p <.001). Among patients receiving ST, at week 24, mean BCVA change was +9.4 letters in 28 CLS-TA patients versus −3.2 letters in 15 sham-control patients (p =.019), while mean CST change was −108.3 µm versus −43.5 µm, respectively (p =.190). No SAEs related to treatment were reported. A clinically meaningful benefit of CLS-TA was noted in UME patients, regardless of concurrent ST usage. Abbreviation and Acronyms CST = central subfield thickness; BCVA = best corrected visual acuity; ME = macular edemaI; IVT = intravitreal; AE = adverse event; FA = fluocinolone acetonide; SD-OCT = spectral-domain optical coherence tomography; NIU = noninfectious uveitis; SAE = serious adverse event; TEAE = treatment emergent adverse event; ITT = intent to treat; CI = confidence interval [ABSTRACT FROM AUTHOR]

Published
2023
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10. What Would Battery Manufacturing Look Like on the Moon and Mars?

Author

Maurel, Alexis, primary, Martinez, Ana C., additional, Dornbusch, Donald A., additional, Huddleston, William H., additional, Seol, Myeong-Lok, additional, Henry, Christopher R., additional, Jones, Jennifer M., additional, Yelamanchi, Bharat, additional, Bakhtar Chavari, Sina, additional, Edmunson, Jennifer E., additional, Sreenivasan, Sreeprasad T., additional, Cortes, Pedro, additional, MacDonald, Eric, additional, and Sherrard, Cameroun G., additional

Published
2023
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12. Final Outcomes from the Randomized RECOVERY Trial of Alfibercept for Retinal Nonperfusion in Proliferative Diabetic Retinopathy

Author

Wykoff, Charles C., primary, Nittala, Muneeswar G., additional, Boone, Cecilia Villanueva, additional, Yu, Hannah J., additional, Fan, Wenying, additional, Velaga, Swetha Bindu, additional, Ehlers, Justis P., additional, Ip, Michael S., additional, Sadda, SriniVas R., additional, Wykoff, Charles C., additional, Zhou, Brenda, additional, Rusakevich, Alexander M., additional, Lampen, Shaun I.R., additional, Srivastava, Sunil K., additional, Reese, Jamie L., additional, Babiuch, Amy, additional, Talcott, Katherine, additional, Figueiredo, Natalia, additional, Hach, Jenna, additional, Ou, William C., additional, Fish, Richard H., additional, Benz, Matthew S., additional, Chen, Eric, additional, Kim, Rosa Y., additional, Major, James C., additional, O’Malley, Ronan E., additional, Brown, David M., additional, Shah, Ankoor R., additional, Schefler, Amy C., additional, Wong, Tien P., additional, and Henry, Christopher R., additional

Published
2022
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18. Myocardial injury and long-term mortality following moderate to severe carbon monoxide poisoning

Author

Henry, Christopher R., Satran, Daniel, Henry, Timothy D., Lindgren, Bruce, Adkinson, Cheryl, and Nicholson, Caren I.

Subjects
Carbon monoxide poisoning -- Risk factors, Cardiac patients -- Health aspects, Heartburn -- Risk factors
Abstract

The association between myocardial injury and long-term mortality in patients following moderate to severe Carbon monoxide (CO) poisoning is determined. The studies reveal that myocardial injury occurs frequently in patients hospitalized for moderate to severe CO poisoning and is a significant predictor of mortality.

Published
2006

23. Clinical outcomes of 4-point scleral fixated 1-piece hydrophobic acrylic equiconvex intraocular lens using polytetrafluoroethylene suture [Corrigendum]

Author

Patel,Nimesh A, Shah,Parth, Yannuzzi,Nicolas A., Ansari,Zubair, Zaveri,Jill S, Relhan,Nidhi, Williams,Basil K, Kuriyan,Ajay E, Henry,Christopher R, Sridhar,Jayanth, Haddock,Luis, Fortun,Jorge A., Albini,Thomas A., Davis,Janet L., Flynn,Harry W., Patel,Nimesh A, Shah,Parth, Yannuzzi,Nicolas A., Ansari,Zubair, Zaveri,Jill S, Relhan,Nidhi, Williams,Basil K, Kuriyan,Ajay E, Henry,Christopher R, Sridhar,Jayanth, Haddock,Luis, Fortun,Jorge A., Albini,Thomas A., Davis,Janet L., and Flynn,Harry W.

Abstract

Patel NA, Shah P, Yannuzzi NA, et al. Clin Ophthalmol. 2018;12:2145–2148.   The intraocular lens (Akreos AO60) studied in this paper is made of hydrophilic acrylic material instead of hydrophobic acrylic. Therefore, the title of this paper is incorrect and should read “Clinical outcomes of 4-point scleral fixated 1-piece hydrophilic acrylic equiconvex intraocular lens using polytetrafluoroethylene suture”. The authors apologize for this error.   Read the original article

Published
2019

25. Clinical outcomes of 4-point scleral fixated 1-piece hydrophobic acrylic equiconvex intraocular lens using polytetrafluoroethylene suture [Corrigendum]

Author

Patel, Nimesh A, primary, Shah, Parth, additional, Yannuzzi, Nicolas A., additional, Ansari, Zubair, additional, Zaveri, Jill S, additional, Relhan, Nidhi, additional, Williams, Basil K, additional, Kuriyan, Ajay E, additional, Henry, Christopher R, additional, Sridhar, Jayanth, additional, Haddock, Luis, additional, Fortun, Jorge A., additional, Albini, Thomas A., additional, Davis, Janet L., additional, and Flynn, Harry W., additional

Published
2019
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26. Clinical outcomes of 4-point scleral fixated 1-piece hydrophobic acrylic equiconvex intraocular lens using polytetrafluoroethylene suture

Author

Patel,Nimesh A, Shah,Parth, Yannuzzi,Nicolas A, Ansari,Zubair, Zaveri,Jill S, Relhan,Nidhi, Williams,Basil K, Kuriyan,Ajay E, Henry,Christopher R, Sridhar,Jayanth, Haddock,Luis, Fortun,Jorge, Albini,Thomas A., Davis,Janet L, Flynn Jr,Harry W, Patel,Nimesh A, Shah,Parth, Yannuzzi,Nicolas A, Ansari,Zubair, Zaveri,Jill S, Relhan,Nidhi, Williams,Basil K, Kuriyan,Ajay E, Henry,Christopher R, Sridhar,Jayanth, Haddock,Luis, Fortun,Jorge, Albini,Thomas A., Davis,Janet L, and Flynn Jr,Harry W

Abstract

Nimesh A Patel, Parth Shah, Nicolas A Yannuzzi, Zubair Ansari, Jill S Zaveri, Nidhi Relhan, Basil K Williams Jr, Ajay E Kuriyan, Christopher R Henry, Jayanth Sridhar, Luis Haddock, Jorge A Fortun, Thomas A Albini, Janet L Davis, Harry W Flynn JrDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA Purpose: To report the visual outcomes and complications of scleral fixated intraocular lenses (IOLs) using Gore-Tex suture.Methods: The current study is a retrospective noncomparative case series including patients who underwent scleral fixation of IOL (Akreos AO60) using Gore-Tex suture from August 2015 to March 2017 at a university teaching center. Primary outcome measures were visual acuity and complications at last follow-up.Results: The current study included 49 eyes of 48 patients. Mean follow-up duration postsurgery was 6.9 months (range: 0.9–29.4 months). The indications for secondary IOL surgery were dislocated IOL in 16/49 (33%), subluxed IOL in 9/49 (18%), dislocated or subluxed crystalline lens in 9/49 (18%), traumatic cataract in 8/49 (16%), and complicated cataract surgery in 7/49 (14%). Mean best-corrected logMAR visual acuity improved from 1±0.7 (20/200 Snellen equivalent) preoperatively to 0.5±0.5 (20/63 Snellen equivalent) at last follow-up. There were no intraoperative complications noted. Early postoperative complications included significant persistent corneal edema (longer than 1 week) in 4/49 (8.2%), ocular hypertension (intraocular pressure ≥25 mmHg) in 8/49 (16.3%), hypotony (intraocular pressure ≤5 mmHg) in 6/49 (12.2%), cystoid macular edema 3/21 (6.1%), IOL tilt 2/49 (4.1%), hyphema in 2/49 (4.1%), and vitreous hemorrhage in 5/49 (4.8%). There was one case of recurrent retinal detachment. One patient presented with an erosion of the Gore-Tex suture through the conjunctiva resulting in a purulent scleritis 6 months after the ini

Published
2018

27. ACUTE MACULAR NEURORETINOPATHY IN SUSAC SYNDROME: A NEW ASSOCIATION.

Author

Yong-Sheng Yang, Zhang, Lily, Asdaghi, Negar, Henry, Christopher R., and Davis, Janet L.

Abstract

Purpose: To report a case of acute macular neuroretinopathy in a patient with Susac syndrome. Methods: Case report. Results: A 39-year-old male patient presented with severe headache, photopsias, and a sudden onset of hearing loss in the right ear. Fluorescein angiography of the right eye revealed multiple branch retinal artery occlusions. Clinical presentation of encephalopathy, hearing loss, and branch retinal artery occlusions, along with characteristic magnetic resonance imaging findings, led to a diagnosis of Susac syndrome. Despite aggressive immunosuppression for four months, the patient later presented with acute macular neuroretinopathy in the left eye. Conclusion: Acute macular neuroretinopathy and Susac is a new association of two well-defined disorders. The concurrence of both disorders supports retinal ischemia as the proximate cause of acute macular neuroretinopathy and inflammation as a potential etiology. [ABSTRACT FROM AUTHOR]

Published
2020
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28. Clinical outcomes of 4-point scleral fixated 1-piece hydrophobic acrylic equiconvex intraocular lens using polytetrafluoroethylene suture

Author

Patel, Nimesh A, primary, Shah, Parth, additional, Yannuzzi, Nicolas A, additional, Ansari, Zubair, additional, Zaveri, Jill S, additional, Relhan, Nidhi, additional, Williams, Basil K, additional, Kuriyan, Ajay E, additional, Henry, Christopher R, additional, Sridhar, Jayanth, additional, Haddock, Luis, additional, Fortun, Jorge, additional, Albini, Thomas A., additional, Davis, Janet L, additional, and Flynn Jr, Harry W, additional

Published
2018
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34. Making a Difference Through Engineer Capacity Building in Africa

Author

ARMY COMMAND AND GENERAL STAFF COLLEGE FORT LEAVENWORTH KS SCHOOL OF ADVANCED MILITARY STUDIES, Henry, Christopher R, ARMY COMMAND AND GENERAL STAFF COLLEGE FORT LEAVENWORTH KS SCHOOL OF ADVANCED MILITARY STUDIES, and Henry, Christopher R

Abstract

The purpose of this monograph is to examine a new way for the United States military to conduct theater security cooperation in sub-Saharan Africa in order to help address the infrastructure deficit found across this environment. This study will focus on examining the utility of establishing or expanding the engineer capabilities of select African militaries in order to help these nations develop their national infrastructure and help enable the African security brigades. This dual-use capability will help the United States indirectly achieve its national security objectives. Expanding national infrastructure will promote economic growth and stability. In times of crisis, it is envisioned that the engineer units can be used to help the regional brigades operate in the austere environment of sub-Saharan Africa. This aid program is purposefully designed to supplement the work of other aid programs being executed by the United States government and other key partners. Simply developing a tactical engineer capability is not enough. The tactical ability is designed to operate in a whole-of-government approach to reinforce the success of other programs. Targeted nations must demonstrate the potential to successfully maintain this capability and put it to good use before precious American tax dollars are spent. In order to analyze this proposal, the infrastructure of four sub-Saharan African nations will be examined to determine if a military engineer asset would prove useful. The analysis will conclude by showing that expanding the engineer capabilities of select African militaries is of marginal utility in expanding national infrastructure and increasing the operational effectiveness of the security brigades.

Published
2014

35. Endophthalmitis following pars plana vitrectomy for vitreous floaters

Author

Henry,Christopher R, Schwartz,Stephen G, Flynn Jr,Harry W, Henry,Christopher R, Schwartz,Stephen G, and Flynn Jr,Harry W

Abstract

Christopher R Henry, Stephen G Schwartz, Harry W Flynn Jr Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA Abstract: A case of Staphylococcus caprae endophthalmitis in a young patient following pars plana vitrectomy for symptomatic vitreous floaters is reported here. Recent literature suggests that there is an increasing trend of performing pars plana vitrectomy for symptomatic floaters. Although rare, the potential risk of endophthalmitis should be explicitly discussed with patients considering surgical intervention for vitreous floaters. Keywords: endophthalmitis, pars plana vitrectomy, vitreous floaters, floaterectomy, posterior vitreous detachment

Published
2014

36. Reply

Author

Henry, Christopher R., primary, Smiddy, William E., additional, and Flynn, Harry W., additional

Published
2014
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41. Role of steroids in the treatment of bacterial keratitis.

Author

Palioura, Sotiria, Henry, Christopher R., Amescua, Guillermo, and Alfonso, Eduardo C.

Subjects
*TREATMENT of keratitis, *STEROID drugs, *CORNEA diseases, *ADRENOCORTICAL hormones, *CLINICAL drug trials
Abstract

Bacterial keratitis can lead to severe visual impairment from corneal ulceration, subsequent scarring, and possible perforation. The mainstay of treatment is topical antibiotics, whereas the use of adjunctive topical corticosteroid drops remains a matter of debate. Herein, we review the rationale for and against the use of topical corticosteroids and we assess their effectiveness and safety in the published randomized controlled trials that have evaluated their role as adjunctive therapy for bacterial corneal ulcers. In the largest study to date, the Steroids for Corneal Ulcers Trial, topical corticosteroid drops were neither helpful nor harmful for the 500 participants as a whole. However, subgroup analyses suggested that topical corticosteroids may be beneficial upon early administration (within 2-3 days after starting antibiotics) for more central corneal ulcers with poorer vision at presentation, for invasive Pseudomonas strains, and for non-Nocardia ulcers. These results are discussed within the limitations of the study. [ABSTRACT FROM AUTHOR]

Published
2016
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46. A Regional System to Provide Timely Access to Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction

Author

Henry, Timothy D., primary, Sharkey, Scott W., additional, Burke, M. Nicholas, additional, Chavez, Ivan J., additional, Graham, Kevin J., additional, Henry, Christopher R., additional, Lips, Daniel L., additional, Madison, James D., additional, Menssen, Katie M., additional, Mooney, Michael R., additional, Newell, Marc C., additional, Pedersen, Wes R., additional, Poulose, Anil K., additional, Traverse, Jay H., additional, Unger, Barbara T., additional, Wang, Yale L., additional, and Larson, David M., additional

Published
2007
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