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1. Impact of Frailty on Outcomes after Surgery in Patients with Cushing’s Disease: Findings from the Multicenter Rapid Registry

Author

Findlay, Matt, additional, Massey, Conner, additional, Rennert, Robert, additional, Lucke-Wold, Brandon, additional, Evans, James, additional, Collopy, Sarah, additional, Kim, Won, additional, Delery, William, additional, Pacione, Donato, additional, Kim, Albert, additional, Silverstein, Julie, additional, Kanga, Mridu, additional, Chicoine, Michael, additional, Gardner, Paul, additional, Valappil, Benita, additional, Abdallah, Hussein, additional, Sarris, Christina, additional, Henricks, Benjamin, additional, Torok, Ildiko, additional, Low, Trevor, additional, Crocker, Tomi, additional, Yuen, Kevin, additional, Viga, Vera, additional, Fernandez-Miranda, Juan, additional, Kshettry, Varun, additional, Little, Andrew, additional, and Karsy, Michael, additional

Published
2024
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2. Surgical Predictors of Cushing's Disease Remission: Pilot Investigations Using the Multicenter Rapid Registry.

Author

Findlay, Matthew, Massey, Conner, Alt, Jeremiah, Rennert, Robert, Couldwell, William, Evans, James, Collopy, Sarah, Kim, Won, Delery, William, Pacione, Donato, Kim, Albert H., Kanga, Mridu, Chicoine, Michael, Gardner, Paul, Valappi, Benita, Zada, Gabriel, Garrett, Trey, Abdallah, Hussein, Sarris, Christina, and Henricks, Benjamin

Subjects
CUSHING'S syndrome, DISEASE remission, PROGRESSION-free survival
Abstract

This article, published in the Journal of Neurological Surgery, explores the factors that contribute to the recurrence of Cushing's disease (CD) after transsphenoidal surgery. The study analyzed data from the Registry of Adenomas of the Pituitary and Related Disorders (RAPID) database, which included 383 CD patients. The results showed that patients who experienced recurrence had a longer postoperative hospital stay, larger tumor volumes, and a higher rate of failed prior treatment. Younger age and the absence of cavernous sinus invasion were identified as potential protective factors against recurrence. The findings suggest that early detection and treatment of tumors may improve outcomes for CD patients. [Extracted from the article]

Published
2024
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