5 results on '"Henríquez, Odessa"'
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2. Performance of cervical cytology and HPV testing for primary cervical cancer screening in Latin America: an analysis within the ESTAMPA study
- Author
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Ramírez, Arianis Tatiana, primary, Valls, Joan, additional, Baena, Armando, additional, Rojas, Freddy David, additional, Ramírez, Katherine, additional, Álvarez, Rodrigo, additional, Cristaldo, Carmen, additional, Henríquez, Odessa, additional, Moreno, Adrián, additional, Reynaga, Daysi Colque, additional, Palma, Hans González, additional, Robinson, Isabel, additional, Hernández, Diana Carolina, additional, Bardales, Rosa, additional, Cardinal, Lucia, additional, Salgado, Yuly, additional, Martínez, Sandra, additional, González, Emmanuel, additional, Guillén, Diego, additional, Fleider, Laura, additional, Tatti, Silvio, additional, Villagra, Verónica, additional, Venegas, Gino, additional, Cruz-Valdez, Aurelio, additional, Valencia, Marleny, additional, Rodríguez, Guillermo, additional, Terán, Carolina, additional, Picconi, María Alejandra, additional, Ferrera, Annabelle, additional, Kasamatsu, Elena, additional, Mendoza, Laura, additional, Calderon, Alejandro, additional, Luciani, Silvana, additional, Broutet, Nathalie, additional, Darragh, Teresa, additional, Almonte, Maribel, additional, Herrero, Rolando, additional, Rol, Mary Luz, additional, Lucas, Eric, additional, Hernández, María de la Luz, additional, Sánchez, Gloria Inés, additional, Murillo, Raul, additional, Jerónimo, Jose, additional, Ferreccio, Catterina, additional, Rodríguez, María Isabel, additional, Cabrera, Yessy, additional, Salgado, Brenda, additional, Colucci, María Celeste, additional, Saino, Maria Agustina, additional, Rodríguez de la Peña, Margarita, additional, Fernández, Daniel Llanos, additional, García, Laura, additional, Caserta, Benedicta, additional, Doimi, Franco, additional, and Lazcano-Ponce, Eduardo, additional
- Published
- 2023
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3. Performance of cervical cytology and HPV testing for primary cervical cancer screening in Latin America : an analysis within the ESTAMPA study
- Author
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Universidad Nacional de Asunción. Instituto de Investigaciones en Ciencias de la Salud, Ramírez, Arianis Tatiana, Valls, Joan, Baena, Armando, Rojas, Freddy David, Ramírez, Katherine, Álvarez, Rodrigo, Cristaldo, Carmen, Henríquez, Odessa, Moreno, Adrián, Colque Reynaga, Daysi, González Palma, Hans, Robinson, Isabel, Hernández, Diana Carolina, Bardales, Rosa, Cardinal, Lucía, Salgado, Yuly, Martínez, Sandra, González, Emmanuel, Guillén, Diego, Fleider, Laura, Tatti, Silvio, Villagra, Verónica, Venegas, Gino, Cruz Valdez, Aurelio, Valencia, Marleny, Rodríguez, Guillermo, Terán, Carolina, Picconi, María Alejandra, Ferrera, Annabelle, Kasamatsu, Elena Satiko, Mendoza Torres, Laura Patricia, Calderón, Alejandro, Luciani, Silvana, Broutet, Nathalie, Darragh, Teresa M., Almonte, Maribel, Herrero, Rolando, Universidad Nacional de Asunción. Instituto de Investigaciones en Ciencias de la Salud, Ramírez, Arianis Tatiana, Valls, Joan, Baena, Armando, Rojas, Freddy David, Ramírez, Katherine, Álvarez, Rodrigo, Cristaldo, Carmen, Henríquez, Odessa, Moreno, Adrián, Colque Reynaga, Daysi, González Palma, Hans, Robinson, Isabel, Hernández, Diana Carolina, Bardales, Rosa, Cardinal, Lucía, Salgado, Yuly, Martínez, Sandra, González, Emmanuel, Guillén, Diego, Fleider, Laura, Tatti, Silvio, Villagra, Verónica, Venegas, Gino, Cruz Valdez, Aurelio, Valencia, Marleny, Rodríguez, Guillermo, Terán, Carolina, Picconi, María Alejandra, Ferrera, Annabelle, Kasamatsu, Elena Satiko, Mendoza Torres, Laura Patricia, Calderón, Alejandro, Luciani, Silvana, Broutet, Nathalie, Darragh, Teresa M., Almonte, Maribel, and Herrero, Rolando
- Abstract
Background. Cervical cytology remains widely used as the initial tool in cervical cancer screening worldwide. WHO guidelines recommend replacing cytology with primary HPV testing to reach cervical cancer elimination goals. We assessed the performance of cytology and high-risk HPV testing to detect cervical precancer, cervical intraepithelial neoplasia (CIN) grade 3 or worse (CIN3+) among women aged 30–64 years participating in the ESTAMPA study. Methods. Women were screened with cytology and HPV across ESTAMPA study centres in Latin America. Screen-positives were referred to colposcopy with biopsy collection and treatment as needed. Those with no evident precancer were recalled at 18-months for a second HPV test to complete disease ascertainment. Performance indicators for cytology and HPV to detect CIN3+ were estimated. Findings. 30,606 participants with available cytology and HPV results were included in the analysis. A total of 440 histologically confirmed CIN3s and 30 cancers were diagnosed. Cytology sensitivity for CIN3+ was 48.5% (95% CI: 44.0–53.0), whereas HPV testing had a sensitivity of 98.1% (95% CI: 96.3–96.7). Specificity was 96.5% (95% CI: 96.3–96.7) using cytology and 88.7% (95% CI: 88.3–89.0) with HPV. Performance estimates varied substantially by study centre for cytology (ranging from 32.1% to 87.5% for sensitivity and from 89.2% to 99.5% for specificity) while for HPV results were more consistent across sites (96.7%–100% and 83.6–90.8%, respectively). Interpretation. The limited and highly variable sensitivity of cytology strongly supports transition to the more robust and reproducible HPV-based cervical screening to ensure progress towards global cervical cancer elimination targets in Latin America.
- Published
- 2023
4. Funcionalidad y satisfacción de usuarios de una red piloto de telesalud en Danlí, Honduras
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Varela, Isabel, primary, Amaya, Gabriel, primary, Gómez, Sandra, primary, Álvarez, Dina, primary, Díaz, Salvador, primary, Bulnes, Juan Pablo, primary, Summer, Andrea, primary, Henríquez, Odessa, primary, and Durón, Reyna M., primary
- Published
- 2020
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5. Impact of knowledge of HPV positivity on cervical cytology performance in latin america.
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Ramírez AT, Mesher D, Baena A, Salgado Y, Kasamatsu E, Cristaldo C, Álvarez R, Rojas FD, Ramírez K, Guyot J, Henríquez O, González Palma H, Flores B, Peñaranda J, Vero MJ, Robinson I, Rol ML, Rodríguez G, Terán C, Ferrera A, Picconi MA, Calderon A, Mendoza L, Wiesner C, Almonte M, and Herrero R
- Abstract
Background: Cervical cytology is recommended by WHO as a triage option in HPV-based cervical cancer screening programmes. We assessed the performance of cytology to detect CIN3+ without and with knowledge of HPV positivity., Methods: Women were screened with cytology and HPV across ESTAMPA study centres in Latin America. Screen-positives were referred to colposcopy with biopsy and treatment as needed. Cytology was initially interpreted without knowing HPV results. A subset of cytologies from HPV-positive women were re-interpreted at the same laboratories, with knowledge of HPV status, blinded to previous cytology and histological diagnosis. Performance indicators for cytology to detect CIN3+ without and with knowledge of HPV positivity were estimated., Findings: A total of 4,087 women were included, of which 490 had histologically confirmed CIN3 + (455 CIN3 and 35 cancers). Cytology sensitivity without knowledge of HPV positivity for CIN3+ was 47.2% (95% CI: 42.5-51.9), whereas with knowledge of HPV positivity, the sensitivity was higher (58.9%, 95% CI: 54.2-63.5), p < .0001. The specificity without knowledge of HPV was 89.4% (95% CI: 88.2-90.5), while with knowledge of HPV positivity was 78.9% (95% CI: 77.4-80.4), p < .0001. Performance estimates varied by study centre for cytology without knowing the HPV positivity, (range from 32.8% to 61.5% for sensitivity; range 80.7% to 98.6% for specificity). Similarly, performance varied with knowledge of HPV positivity (36.1% to 93.4% for sensitivity; 39.6% to 98.6% for specificity)., Conclusion: The increase in sensitivity of cytology with HPV knowledge was limited and highly variable, reinforcing the need for alternative triage methods to support cervical cancer elimination goals., (© The Author(s) 2024. Published by Oxford University Press.)
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- 2024
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