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37 results on '"Hennig, Oliver"'

1. Diagnose- und Aufnahmezentrum: Etablierung und Evaluation einer integrierten translationalen Infrastruktur für die klinisch-psychiatrische Forschung

Author

Braun, Urs, Hennig, Oliver, Forstner, Johanna, Gerhardt, Sarah, Deffaa, Mirjam, Hirjak, Dusan, Deuschle, Michael, Koopmann, Anne, Wisch, Christian, Fritz, Melanie, Ende, Gabriele, Tost, Heike, Schöfer, Peter, Bischoff, Stefan, Janta, Matthias, Kiefer, Falk, Schmahl, Christian, Banaschewski, Tobias, and Meyer-Lindenberg, Andreas

Published
2024
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6. Female sex and burden of depressive symptoms predict insufficient response to telemedical treatment in adult attention-deficit/hyperactivity disorder: results from a naturalistic patient cohort during the COVID-19 pandemic

Author

Praus, Peter, primary, Proctor, Tanja, additional, Rohrmann, Tobias, additional, Benedyk, Anastasia, additional, Tost, Heike, additional, Hennig, Oliver, additional, Meyer-Lindenberg, Andreas, additional, and Wahl, Anna-Sophia, additional

Published
2023
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10. Time to go green?

Author

Nigg, Carina, primary, Schipperijn, Jasper, additional, Hennig, Oliver, additional, Petzold, Moritz Bruno, additional, Rulf, Ellen, additional, Meyer-Lindenberg, Andreas, additional, Tost, Heike, additional, Ebner-Priemer, Ulrich W., additional, and Reichert, Markus, additional

Published
2022
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12. Time to go green?

Author

Nigg, Carina, Schipperijn, Jasper, Hennig, Oliver, Petzold, Moritz Bruno, Rulf, Ellen, Meyer-Lindenberg, Andreas, Tost, Heike, Ebner-Priemer, Ulrich W., and Reichert, Markus

Subjects
790 Sports, games & entertainment
Published
2022

14. Ambulatory assessment for precision psychiatry: Foundations, current developments and future avenues

Author

Reichert, Markus, primary, Gan, Gabriela, additional, Renz, Malika, additional, Braun, Urs, additional, Brüßler, Sarah, additional, Timm, Irina, additional, Ma, Ren, additional, Berhe, Oksana, additional, Benedyk, Anastasia, additional, Moldavski, Alexander, additional, Schweiger, Janina I., additional, Hennig, Oliver, additional, Zidda, Francesca, additional, Heim, Christine, additional, Banaschewski, Tobias, additional, Tost, Heike, additional, Ebner-Priemer, Ulrich W., additional, and Meyer-Lindenberg, Andreas, additional

Published
2021
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15. Monitoring the crystallization of two enzymes in real time by dynamic light scattering

Author

Rollet, Kévin, primary, de Wijn, Raphaël, additional, Engilberge, Sylvain, additional, McEwen, Alastair G., additional, Hennig, Oliver, additional, Betet, Heike, additional, Mörl, Mario, additional, Riobé, François, additional, Maury, Olivier, additional, Girard, E., additional, Bénas, Philippe, additional, Lorber, Bernard, additional, and Sauter, Claude, additional

Published
2021
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17. Adaptation of the Romanomermis culicivorax CCA-Adding Enzyme to Miniaturized Armless tRNA Substrates

Author

Hennig, Oliver, Philipp, Susanne, Bonin, Sonja, Rollet, Kévin, Kolberg, Tim, Jühling, Tina, Betat, Heike, Sauter, Claude, Mörl, Mario, Universität Leipzig [Leipzig], Architecture et Réactivité de l'ARN (ARN), Institut de biologie moléculaire et cellulaire (IBMC), and Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Mermithoidea, Base Sequence, CCA-adding enzyme, RNA Nucleotidyltransferases, co-evolution, Article, Protein Structure, Secondary, evolutionary plasticity, Substrate Specificity, lcsh:Chemistry, Kinetics, minimalized armless tRNAs, RNA, Transfer, lcsh:Biology (General), lcsh:QD1-999, Biocatalysis, tRNA nucleotidyltransferase, Animals, Humans, Nucleic Acid Conformation, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Amino Acid Sequence, lcsh:QH301-705.5
Abstract

The mitochondrial genome of the nematode Romanomermis culicivorax encodes for miniaturized hairpin-like tRNA molecules that lack D- as well as T-arms, strongly deviating from the consensus cloverleaf. The single tRNA nucleotidyltransferase of this organism is fully active on armless tRNAs, while the human counterpart is not able to add a complete CCA-end. Transplanting single regions of the Romanomermis enzyme into the human counterpart, we identified a beta-turn element of the catalytic core that&mdash, when inserted into the human enzyme&mdash, confers full CCA-adding activity on armless tRNAs. This region, originally identified to position the 3&prime, end of the tRNA primer in the catalytic core, dramatically increases the enzyme&rsquo, s substrate affinity. While conventional tRNA substrates bind to the enzyme by interactions with the T-arm, this is not possible in the case of armless tRNAs, and the strong contribution of the beta-turn compensates for an otherwise too weak interaction required for the addition of a complete CCA-terminus. This compensation demonstrates the remarkable evolutionary plasticity of the catalytic core elements of this enzyme to adapt to unconventional tRNA substrates.

Published
2020

18. A neural mechanism for affective well-being: Subgenual cingulate cortex mediates real-life effects of nonexercise activity on energy

Author

Reichert, Markus, Braun, Urs, Gan, Gabriela, Reinhard, Iris, Giurgiu, Marco, Ma, Ren, Zang, Zhenxiang, Hennig, Oliver, Koch, Elena D., Wieland, Lena, Schweiger, Janina, Inta, Dragos, Hoell, Andreas, Akdeniz, Ceren, Zipf, Alexander, Ebner-Priemer, Ulrich W., Tost, Heike, and Meyer-Lindenberg, Andreas

Subjects
Athletic & outdoor sports & games, Emotions, SciAdv r-articles, Life Sciences, Brain, Humans, ddc:796, Exercise, Gyrus Cinguli, Magnetic Resonance Imaging, Research Articles, Research Article, Neuroscience
Abstract

A neural mechanism underlying the real-life effects of nonexercise activity on well-being promises novel intervention targets., Physical activity substantially improves well-being and mental health, but the underlying brain processes remain unclear. Most research concerns exercise, although the majority of everyday human behaviors, such as walking or stair climbing, are nonexercise activities. Combining neuroimaging with ecological assessment of activity and GPS-triggered smartphone diaries, we show a specific association of nonexercise activity with energy in two independent samples mediated by the subgenual part of the anterior cingulate cortex (sgACC), a key emotion regulatory site. Furthermore, energy predicted a range of mental health metrics. sgACC volume moderated humans’ emotional gain from nonexercise activity in real life: Individuals with low sgACC volume, a risk factor for depression, felt less energized when inactive but benefited more from periods of high nonexercise activity. This suggests an everyday life mechanism affecting affective well-being in the general population and, if substantiated in patient samples, a risk and resilience process for mood disorders.

Published
2020

19. FASTER and SCOTT&EVA Trainings for Adults with High-Functioning Autism Spectrum Disorder (ASD): Study Protocol for a Randomized Controlled Trial.

Author

Elst, Ludger Tebartz van, primary, Fangmeier, Thomas, additional, Schaller, Ulrich Max, additional, Hennig, Oliver, additional, Kieser, Meinhard, additional, Koelkebeck, Katja, additional, Kuepper, Charlotte, additional, Roesner, Veit, additional, Wildgruber, Dirk, additional, and Dziobek, Isabel, additional

Published
2021
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21. Monitoring the Production of High Diffraction-Quality Crystals of Two Enzymes in Real Time Using In Situ Dynamic Light Scattering

Author

de Wijn, Raphaël, primary, Rollet, Kévin, additional, Engilberge, Sylvain, additional, McEwen, Alastair, additional, Hennig, Oliver, additional, Betat, Heike, additional, Mörl, Mario, additional, Riobé, François, additional, Maury, Olivier, additional, Girard, Eric, additional, Bénas, Philippe, additional, Lorber, Bernard, additional, and Sauter, Claude, additional

Published
2020
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23. A simple and versatile microfluidic device for efficient biomacromolecule crystallization and structural analysis by serial crystallography

Author

de Wijn, Raphaël, primary, Hennig, Oliver, additional, Roche, Jennifer, additional, Engilberge, Sylvain, additional, Rollet, Kevin, additional, Fernandez-Millan, Pablo, additional, Brillet, Karl, additional, Betat, Heike, additional, Mörl, Mario, additional, Roussel, Alain, additional, Girard, Eric, additional, Mueller-Dieckmann, Christoph, additional, Fox, Gavin C., additional, Olieric, Vincent, additional, Gavira, José A., additional, Lorber, Bernard, additional, and Sauter, Claude, additional

Published
2019
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36. Hochleistungs-Hybrid-Lokomotive Sr3 für Finnland.

Author

Bleckmann, Ulrich, Becker, Christian, and Hennig, Oliver

Abstract

Siemens and VR (Valtion Rautatiet), Finland's national rail operator, concluded a contract in February 2014 for the supply of 80 electric locomotives with extensive requirements. The locomotives should not only be able to pull high-speed passenger trains at up to 200 km/h and heavy-duty freight traffic, but also be capable of performing shunting services on non-electrified tracks. For this purpose, they are also equipped with radio control. Many equipment packages for the specific operating requirements in Finland, for energy-saving, efficient operation, and for the comfort of the driver characterize the new Sr3 series as well as double heading capability with the earlier Sr2 series and push-pull trains. Siemens used the modularity of the existing Vectron platform to implement these requirements to the latter. This article describes the new locomotive, which is the first representative of the Nordland version of the Vectron. It includes many innovations, and has been specifically designed for the severe climatic conditions of the North Scandinavian winter. This also makes it the basis for further Vectron versions intended for reliable use in the north of Norway and Sweden. The article focuses on presenting the technical features of the Sr3, but also outlines its maintenance, the history of the Vectron in Scandinavia, and the transport of the broad gauge Sr3 to Finland. [ABSTRACT FROM AUTHOR]

Published
2016

37. A neural mechanism for affective well-being: Subgenual cingulate cortex mediates real-life effects of nonexercise activity on energy.

Author

Reichert M, Braun U, Gan G, Reinhard I, Giurgiu M, Ma R, Zang Z, Hennig O, Koch ED, Wieland L, Schweiger J, Inta D, Hoell A, Akdeniz C, Zipf A, Ebner-Priemer UW, Tost H, and Meyer-Lindenberg A

Subjects
Emotions, Exercise, Humans, Magnetic Resonance Imaging, Brain, Gyrus Cinguli
Abstract

Physical activity substantially improves well-being and mental health, but the underlying brain processes remain unclear. Most research concerns exercise, although the majority of everyday human behaviors, such as walking or stair climbing, are nonexercise activities. Combining neuroimaging with ecological assessment of activity and GPS-triggered smartphone diaries, we show a specific association of nonexercise activity with energy in two independent samples mediated by the subgenual part of the anterior cingulate cortex (sgACC), a key emotion regulatory site. Furthermore, energy predicted a range of mental health metrics. sgACC volume moderated humans' emotional gain from nonexercise activity in real life: Individuals with low sgACC volume, a risk factor for depression, felt less energized when inactive but benefited more from periods of high nonexercise activity. This suggests an everyday life mechanism affecting affective well-being in the general population and, if substantiated in patient samples, a risk and resilience process for mood disorders., (Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).)

Published
2020
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