1,732 results on '"Hengstler, Jan G."'
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2. Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food
3. Role of albumin in the metabolism and excretion of ochratoxin A
4. Acetaminophen overdose causes a breach of the blood–bile barrier in mice but not in rats
5. Integrated data from intravital imaging and HPLC–MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats
6. Basal MET phosphorylation is an indicator of hepatocyte dysregulation in liver disease
7. Correction: Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food
8. Basic concepts of mixture toxicity and relevance for risk evaluation and regulation
9. PFASs–restriction proposal commentary on ECHA’s Annex XV restriction report, proposal for a restriction, March 2023
10. Comparative metabolism of aflatoxin B1 in mouse, rat and human primary hepatocytes using HPLC–MS/MS
11. Transcriptome-based prediction of drugs, inhibiting cardiomyogenesis in human induced pluripotent stem cells
12. Alterations in the hepatocyte epigenetic landscape in steatosis
13. Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth
14. Proteome analysis of monocytes implicates altered mitochondrial biology in adults reporting adverse childhood experiences
15. Guidance for statistical design and analysis of toxicological dose–response experiments, based on a comprehensive literature review
16. G × E interactions as a basis for toxicological uncertainty
17. The TGF-β1 target WISP1 is highly expressed in liver cirrhosis and cirrhotic HCC microenvironment and involved in pro- and anti-tumorigenic effects
18. Loss of Toll-like receptor 9 protects from hepatocellular carcinoma in murine models of chronic liver disease
19. PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat
20. The impact of physical fitness, social life, and cognitive functions on work ability in middle-aged and older adults
21. Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis
22. Induction of steatosis in primary human hepatocytes recapitulates key pathophysiological aspects of metabolic dysfunction-associated steatotic liver disease
23. Model predicts fundamental role of biomechanical control of cell cycle progression during liver regeneration after partial hepatectomy
24. Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A
25. Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation
26. EDI3 knockdown in ER-HER2+ breast cancer cells reduces tumor burden and improves survival in two mouse models of experimental metastasis
27. Classification of hepatotoxicity of compounds based on cytotoxicity assays is improved by additional interpretable summaries of high-dimensional gene expression data
28. Risk assessment of parabens in a transcriptomics-based in vitro test
29. Ricin: an ancient toxicant, but still an evergreen
30. OS-088-YI Selective ablation of Caspase 8 in hepatocytes ameliorates development of metabolic dysfunction-associated steatohepatitis following hepatocyte-specific JNK deletion
31. LBP-017 Liver-kidney crosstalk: the influence of hepatic oxalate release on kidney gluconeogenesis
32. Sublethal necroptosis signaling promotes inflammation and liver cancer
33. Genome-wide Association Study of Bladder Cancer Reveals New Biological and Translational Insights
34. Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins
35. Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity
36. Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes
37. Stellungnahme zu Acetaldehyd als Aromastoff: Aspekte der Risikobewertung
38. Chronic stress is associated with specific path integration deficits
39. Evaluation of the genotoxic potential of acrylamide: Arguments for the derivation of a tolerable daily intake (TDI value)
40. Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy
41. Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds—a hypothesis
42. Correction: In memoriam Thomas Gebel
43. Recent research on Novichok
44. Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells
45. In memoriam Thomas Gebel
46. Long-term prognostic significance of HER2-low and HER2-zero in node-negative breast cancer
47. In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay
48. td2pLL: An intuitive time-dose-response model for cytotoxicity data with varying exposure durations
49. Enigmatic mechanism of the N-vinylpyrrolidone hepatocarcinogenicity in the rat
50. Importance of Xenobiotic Metabolism: Mechanistic Considerations Relevant for Regulation
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