1. In vitro anthelmintic activity of Chaetomorpha vieillardii ethanolic extract against adult worm motility and egg-hatching of Haemonchus contortus from sheep
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Awistaros Angger Sakti, Bambang Suwignyo, Ahmad Sofyan, Chusnul Hanim, Hendra Herdian, Jasmadi Jasmadi, Tiurma Pasaribu, Hardi Julendra, Gunawan Gunawan, Pustika Ratnawati, Lilis Hartati, Syifa Adisa Eminita Tarigan, and kustantinah Adiwimarta
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Veterinary medicine ,SF600-1100 - Abstract
This study aimed to evaluate the potential of macroalgae Chaetomorpha vieillardii as an in vitro candidate for bio-anthelmintic. Adult Worm Motility Test (AWMT) was conducted at concentration levels of 2 mg/mL, 4 mg/mL, and 6 mg/mL of C. vieillardii ethanol extract on 150 female H. contortus worms, randomly divided into 6 treatments with 5 replications, using a two way completely randomized factorial design. 0.9% sodium chloride was used as a negative control, and albendazole at 0.5 and 2 mg/mL served as positive controls. Worm motility observations were performed at 0, 0.25, 0.5, 1, 2, and subsequent time intervals until 100% of the worms were deceased. The identical treatment was applied to the egg hatching inhibiting test (EHIT) using a completely randomized design in a one-way pattern by observing the number of eggs at 0 and 24 hours. The results showed that the concentration level of C. vieillardii ethanol extract and the observation time significantly influenced (P
- Published
- 2024
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