Search

Your search keyword '"Hench, Larry L."' showing total 591 results
Start Over Author "Hench, Larry L."
591 results on '"Hench, Larry L."'

8. Introduction

Author

Hench, Larry L., Wilson, June, Hench, Larry L., editor, and Wilson, June, editor

Published
1996
Full Text
View/download PDF

9. Summary

Author

Hench, Larry L., Wilson, June, Hench, Larry L., editor, and Wilson, June, editor

Published
1996
Full Text
View/download PDF

15. In vitro bioactivity of polymer matrices reinforced with a bioactive glass phase

Author

Oréfice Rodrigo L., Hench Larry L., and Brennan Anthony B.

Subjects
bioactive polymer composites, biomaterials, Chemistry, QD1-999
Abstract

Composites that can mimic the in vitro bioactive behavior of bioactive glasses were designed to fulfill two main features of bioactive glasses that are responsible for their high bond-to-bone rates: (1) capability of providing ions such as calcium and phosphate to the nearby environment and (2) ideal surface structure that allows fast heterogeneous precipitation of hydroxy-carbonate-apatite (HCA). The novel composites were prepared by incorporating bioactive glass particles into polymer matrices. The in vitro bioactivity test was performed by introducing samples into a buffered solution as well as into a simulated body fluid solution. FTIR was used to evaluate the kinetics of HCA (hydroxy-carbonate-apatite) precipitation. The results showed that the obtained composites can supply ions, such as silicates and phosphates in rates and concentrations comparable or superior than bulk bioactive glasses. Moreover, the surface chemistry of the composites was altered to mimic the surface of bioactive glasses. It was demonstrated that the in vitro bioactivity of the composites was enhanced by chemically modifying polymer surfaces through the introduction of special alkoxysilane groups.

Published
2000

39. Contributors

Author

Abramson, Sascha, primary, Ackermann, D. Michael, additional, Akins, Robert, additional, Anders, Richard, additional, Andersen, Phillip J., additional, Anderson, James M., additional, Ankrum, James A., additional, Anseth, Kristi S., additional, Antonucci, Joe, additional, Atzet, Sarah, additional, Badylak, Stephen F., additional, Baura, Gail D., additional, Bellamkonda, Ravi V., additional, Best, Serena M., additional, Bhumiratana, Sarindr, additional, Bianco, Richard W., additional, Bokros, Jack C., additional, Borovetz, Harvey S., additional, Boskey, Adele L., additional, Brown, Justin L., additional, Brown, Bryan N., additional, Brown, Stanley A., additional, Brunski, John B., additional, Cahn, Fred, additional, Ritchie, Alastair Campbell, additional, Caplan, Arnold I., additional, Carpenedo, Richard L., additional, Chilkoti, Ashutosh, additional, Chung, Sangwon, additional, Cimetta, Elisa, additional, Cleary, Gary, additional, Clements, Isaac P., additional, Colas, André, additional, Coleman, Kelly P., additional, Conway, Daniel E., additional, Cooper, Stuart L., additional, Costerton, Bill, additional, Coury, Arthur J., additional, Cunanan, Crystal, additional, Curtis, Jim, additional, D’Amore, Antonio, additional, DeMeo, Patrick, additional, Desai, Tejal A., additional, Dickens, Sabine, additional, Domingo, Gonzalo, additional, Duncan, Elaine, additional, Eskin, Suzanne G., additional, Feigal, David W., additional, Ferreira, Lino, additional, Fuller, Jason, additional, Gallegos, Robert P., additional, Gawalt, Ellen, additional, Ghosh, Kaustabh, additional, Ghosn, Bilal, additional, Gilbert, Thomas W., additional, Glaser, Drew Elizabeth, additional, Godier-Furnemont, Amandine, additional, Gombotz, Wayne R., additional, Grainger, David W., additional, Grunkemeier, Gary L., additional, Hacking, S. Adam, additional, Hallab, Nadim James, additional, Hall-Stoodley, Luanne, additional, Hanson, Stephen R., additional, Haubold, Axel D., additional, Hauch, Kip D., additional, Hawkins, Kenneth R., additional, Heath, Daniel E., additional, Helm, Douglas L., additional, Hench, Larry L., additional, Hensten, Arne, additional, Hill, Ryan T., additional, Hobson, Christopher, additional, Hoerstrup, Simon P., additional, Hoffman, Allan S., additional, Horbett, Thomas A., additional, Hubbell, Jeffrey A., additional, Humayun, Mark S., additional, Ideker, Ray, additional, Ingber, Donald E., additional, Jain, Rakhi, additional, Jacob, Jean, additional, Jacobs, Joshua James, additional, Jacobsen, Nils, additional, Jin, Ruyun, additional, Johnson, Richard J., additional, Karp, Jeffrey M., additional, Kasper, F. Kurtis, additional, Kathju, Sandeep, additional, Khademhosseini, Ali, additional, Kim, Sungwon, additional, King, Martin W., additional, Kleiner, Lothar W., additional, Kohn, Joachim, additional, Koschwanez, Heidi E., additional, Kumbar, Sangamesh G., additional, Kuo, Catherine K., additional, LaFleur, Lisa, additional, Lahti, Matthew T., additional, Lambert, Byron, additional, Langer, Robert, additional, Laurencin, Cato T., additional, Lee-Parritz, David, additional, Lemons, Jack E., additional, Levin, Mark, additional, Levy, Robert J., additional, Lewerenz, Gregory M., additional, Li, Wan-Ju, additional, Lin, Chien-Chi, additional, Liu, Fang, additional, Lowrie, William G., additional, Lu, Ying, additional, Lysaght, Michael J., additional, Maidhof, Robert, additional, Mansbridge, J.N., additional, Cristina, M., additional, Martins, L., additional, Martin, Jeffrey, additional, Mayesh, Jay P., additional, McDevitt, Todd C., additional, McIntire, Larry V., additional, Merrit, Katharine, additional, Migliaresi, Claudio, additional, Mikos, Antonios G., additional, Misch, Carl E., additional, Mitchell, Richard N., additional, More, Robert B., additional, Moss, Christa W., additional, Munson, Jennifer M., additional, Navarro, Melba, additional, Nerem, Robert M., additional, Ogawa, Rei, additional, Orgill, Britlyn D., additional, Orgill, Dennis P., additional, Padera, Robert F., additional, Pandit, Abhay, additional, Park, Kinam, additional, Patel, Anil S., additional, Peck, Roger B., additional, Peckham, P. Hunter, additional, Peppas, Nicholas A., additional, Pereira, Maria Nunes, additional, Planell, Josep, additional, Popat, Ketul C., additional, Prestwich, Glenn D., additional, Pun, Suzie H., additional, Rabolt, John, additional, Rainbow, Roshni S., additional, Rajab, Taufiek, additional, Ratner, Buddy D., additional, Reichert, William M., additional, Rivard, Andrew L., additional, Rowley, Adrian P., additional, Ruan, Gang, additional, Sacks, Michael, additional, Sarkar, Debanjan, additional, Schaefer, Sebastian, additional, Schmidt, Christine E., additional, Schoen, Frederick J., additional, Schutte, Stacey C., additional, Sefton, Michael V., additional, Shalaby, Shalaby W., additional, Shirtliff, Mark, additional, Simon, Marc A., additional, Singh, Milind, additional, Slack, Steven M., additional, Spelman, Francis A., additional, Starr, Albert, additional, Stayton, Patrick S., additional, Steinert, Roger, additional, Stoodley, Paul, additional, Suri, Shalu, additional, Swi Chang, Thomas Ming, additional, Tandon, Nina, additional, Tanguay, Armand R., additional, Taylor, M. Scott, additional, Teo, Grace S.L., additional, Thodeti, Charles K., additional, Tolkoff, Joshua, additional, Treiser, Matthew, additional, Tuan, Rocky S., additional, Tucker, Erik I., additional, Venugopalan, Ramakrishna, additional, Vicari, Angela R., additional, Viney, Christopher, additional, Voight, Jessica M., additional, Vunjak-Novakovic, Gordana, additional, Wagner, William R., additional, Wang, Lian, additional, Wasiluk, Karen R., additional, Watts, David Christopher, additional, Weigl, Bernhard H., additional, Weiland, James D., additional, Whalen, John J., additional, Williams, David F., additional, Williams, Rachel L., additional, Wilson, John T., additional, Wilson, Clive G., additional, Winter, Jessica, additional, Wolf, Michael F., additional, Wright, Jeremy C., additional, Yager, Paul, additional, and Zhao, Weian, additional

Published
2013
Full Text
View/download PDF

41. In situ spectral monitoring of mRNA translation in embryonic stem cells during differentiation in vitro

Author

Notingher, Ioan, Bisson, Isabelle, Bishop, Anne E., Randle, Wesley L., Polak, Julia M.P., and Hench, Larry L.

Subjects
Chemistry, Analytic -- Research, Chemistry
Abstract

Raman microspectroscopy was used to determine biochemical markers during the differentiation of embryonic murine stem cells (mES) in vitro. Such markers are useful to determine the differentiation status of ES cells cultured on biomaterials, Raman spectra of mES cells as undifferentiated, spontaneously differentiated (4 days), and differentiated cells via formation of embryoid bodies (16, 20 days) were analyzed. Unsupervised hierarchical cluster analysis and principal component analysis were used to determine biochemical differences between mES cells in various states of differentiation. The undifferentiated cells were characterized by high scores of the first principal component (PC1, 49% variance). Similarity between the PC1 loading and the Raman spectrum of RNA indicated a high concentration of RNA in mES cells compared to differentiated cells. The ratio between the peak areas of RNA and proteins was used as a measure of mRNA translation. Using the same peak area ratio, it was possible to differentiate even between mES as undifferentiated and in early stages of differentiation (4 days). These findings were correlated with biological studies reporting high levels of nontranslated mRNA during early embryonic development. Therefore, the RNA translation obtained from the Raman spectra can be used as marker of differentiation state of mES cells.

Published
2004

Catalog

Books, media, physical & digital resources
See catalog results