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4. Changes in physical activity patterns from adolescence to young adulthood: The Belinda study

Author

Vanhelst, J., primary, Morcel, J., additional, Béghin, L., additional, Drumez, E., additional, Labreuche, J., additional, Polito, A., additional, De Ruyter, T., additional, Censi, L., additional, Ferrari, M., additional, Miguel-Berges, M.L., additional, Michels, N., additional, De Henauw, S., additional, Moreno, L.A., additional, and Gottrand, F., additional

Published
2023
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8. Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants

Author

Zhou, B, Lu, Y, Hajifathalian, K, Bentham, J, Di Cesare, M, Danaei, G, Bixby, H, Cowan, MJ, Ali, MK, Taddei, C, Lo, WC, Reis-Santos, B, Stevens, GA, Riley, LM, Miranda, JJ, Bjerregaard, P, Rivera, JA, Fouad, HM, Ma, G, Mbanya, JC, McGarvey, ST, Mohan, V, Onat, A, Pilav, A, Ramachandran, A, Romdhane, HB, Paciorek, CJ, Bennett, JE, Ezzati, M, Abdeen, ZA, Abdul Kadir, K, Abu-Rmeileh, NM, Acosta-Cazares, B, Adams, R, Aekplakorn, W, Aguilar-Salinas, CA, Agyemang, C, Ahmadvand, A, Al-Othman, AR, Alkerwi, A, Amouyel, P, Amuzu, A, Andersen, LB, Anderssen, SA, Anjana, RM, Aounallah-Skhiri, H, Aris, T, Arlappa, N, Arveiler, D, Assah, FK, Avdicová, M, Azizi, F, Balakrishna, N, Bandosz, P, Barbagallo, CM, Barceló, A, Batieha, AM, Baur, LA, Benet, M, Bernabe-Ortiz, A, Bharadwaj, S, Bhargava, SK, Bi, Y, Bjertness, E, Bjertness, MB, Björkelund, C, Blokstra, A, Bo, S, Boehm, BO, Boissonnet, CP, Bovet, P, Brajkovich, I, Breckenkamp, J, Brenner, H, Brewster, LM, Brian, GR, Bruno, G, Bugge, A, Cabrera de León, A, Can, G, Cândido, AP, Capuano, V, Carlsson, AC, Carvalho, MJ, Casanueva, FF, Casas, JP, Caserta, CA, Castetbon, K, Chamukuttan, S, Chaturvedi, N, Chen, CJ, Chen, F, Chen, S, Cheng, CY, Chetrit, A, Chiou, ST, Cho, Y, Chudek, J, Cifkova, R, Claessens, F, Concin, H, Cooper, C, Cooper, R, Costanzo, S, Cottel, D, Cowell, C, Crujeiras, AB, D'Arrigo, G, Dallongeville, J, Dankner, R, Dauchet, L, de Gaetano, G, De Henauw, S, Deepa, M, Dehghan, A, Deschamps, V, Dhana, K, Di Castelnuovo, AF, Djalalinia, S, Doua, K, Drygas, W, Du, Y, Dzerve, V, Egbagbe, EE, Eggertsen, R, El Ati, J, Elosua, R, Erasmus, RT, Erem, C, Ergor, G, Eriksen, L, Escobedo-de la Peña, J, Fall, CH, Farzadfar, F, Felix-Redondo, FJ, Ferguson, TS, Fernández-Bergés, D, Ferrari, M, Ferreccio, C, Feskens, EJ, Finn, JD, Föger, B, Foo, LH, Forslund, AS, Francis, DK, Franco Mdo, C, Franco, OH, Frontera, G, Furusawa, T, Gaciong, Z, Garnett, SP, Gaspoz, JM, Gasull, M, Gates, L, Geleijnse, JM, Ghasemian, A, Ghimire, A, Giampaoli, S, Gianfagna, F, Giovannelli, J, Giwercman, A, Gross, MG, González Rivas, JP, Gorbea, MB, Gottrand, F, Grafnetter, D, Grodzicki, T, Grøntved, A, Gruden, G, Gu, D, Guan, OP, Guerrero, R, Guessous, I, Guimaraes, AL, Gutierrez, L, Hambleton, IR, Hardy, R, Hari Kumar, R, Hata, J, He, J, Heidemann, C, Herrala, S, Hihtaniemi, IT, Ho, SY, Ho, SC, Hofman, A, Hormiga, CM, Horta, BL, Houti, L, Howitt, C, Htay, TT, Htet, AS, Htike, MM, Hu, Y, Hussieni, AS, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, AG, Ibrahim, MM, Ikeda, N, Ikram, MA, Irazola, VE, Islam, M, Iwasaki, M, Jacobs, JM, Jafar, T, Jamil, KM, Jasienska, G, Jiang, CQ, Jonas, JB, Joshi, P, Kafatos, A, Kalter-Leibovici, O, Kasaeian, A, Katz, J, Kaur, P, Kavousi, M, Keinänen-Kiukaanniemi, S, Kelishadi, R, Kengne, AP, Kersting, M, Khader, YS, Khalili, D, Khang, YH, Kiechl, S, Kim, J, Kolsteren, P, Korrovits, P, Kratzer, W, Kromhout, D, Kujala, UM, Kula, K, Kyobutungi, C, Laatikainen, T, Lachat, C, Laid, Y, Lam, TH, Landrove, O, Lanska, V, Lappas, G, Laxmaiah, A, Leclercq, C, Lee, J, Lehtimäki, T, Lekhraj, R, León-Muñoz, LM, Li, Y, Lim, WY, Lima-Costa, MF, Lin, HH, Lin, X, Lissner, L, Lorbeer, R, Lozano, JE, Luksiene, D, Lundqvist, A, Lytsy, P, Machado-Coelho, GL, Machi, S, Maggi, S, Magliano, DJ, Makdisse, M, Mallikharjuna Rao, K, Manios, Y, Manzato, E, Margozzini, P, Marques-Vidal, P, Martorell, R, Masoodi, SR, Mathiesen, EB, Matsha, TE, McFarlane, SR, McLachlan, S, McNulty, BA, Mediene-Benchekor, S, Meirhaeghe, A, Menezes, AM, Merat, S, Meshram, II, Mi, J, Miquel, JF, Mohamed, MK, Mohammad, K, Mohammadifard, N, Mohd Yusoff, MF, Møller, NC, Molnár, D, Mondo, CK, Morejon, A, Moreno, LA, Morgan, K, Moschonis, G, Mossakowska, M, Mostafa, A, Mota, J, Motta, J, Mu, TT, Muiesan, ML, Müller-Nurasyid, M, Mursu, J, Nagel, G, Námešná, J, Nang, EE, NangThetia, VB, Navarrete-Muñoz, EM, Ndiaye, NC, Nenko, I, Nervi, F, Nguyen, ND, Nguyen, QN, Nieto-Martínez, RE, Ning, G, Ninomiya, T, Noale, M, Noto, D, Nsour, MA, Ochoa-Avilés, AM, Oh, K, Ordunez, P, Osmond, C, Otero, JA, Owusu-Dabo, E, Pahomova, E, Palmieri, L, Panda-Jonas, S, Panza, F, Parsaeian, M, Peixoto, SV, Pelletier, C, Peltonen, M, Peters, A, Peykari, N, Pham, ST, Pitakaka, F, Piwonska, A, Piwonski, J, Plans-Rubió, P, Porta, M, Portegies, ML, Poustchi, H, Pradeepa, R, Price, JF, Punab, M, Qasrawi, RF, Qorbani, M, Radisauskas, R, Rahman, M, Raitakari, O, Rao, SR, Ramke, J, Ramos, R, Rampal, S, Rathmann, W, Redon, J, Reganit, PF, Rigo, F, Robinson, SM, Robitaille, C, Rodríguez-Artalejo, F, Rodriguez-Perez Mdel, C, Rodríguez-Villamizar, LA, Rojas-Martinez, R, Ronkainen, K, Rosengren, A, Rubinstein, A, Rui, O, Ruiz-Betancourt, BS, Russo Horimoto, RV, Rutkowski, M, Sabanayagam, C, Sachdev, HS, Saidi, O, Sakarya, S, Salanave, B, Salonen, JT, Salvetti, M, Sánchez-Abanto, J, Santos, D, dos Santos, RN, Santos, R, Saramies, JL, Sardinha, LB, Sarrafzadegan, N, Saum, KU, Scazufca, M, Schargrodsky, H, Scheidt-Nave, C, Sein, AA, Sharma, SK, Shaw, JE, Shibuya, K, Shin, Y, Shiri, R, Siantar, R, Sibai, AM, Simon, M, Simons, J, Simons, LA, Sjostrom, M, Slowikowska-Hilczer, J, Slusarczyk, P, Smeeth, L, Snijder, MB, So, HK, Sobngwi, E, Söderberg, S, Solfrizzi, V, Sonestedt, E, Soumare, A, Staessen, JA, Stathopoulou, MG, Steene-Johannessen, J, Stehle, P, Stein, AD, Stessman, J, Stöckl, D, Stokwiszewski, J, Stronks, K, Strufaldi, MW, Sun, CA, Sundström, J, Sung, YT, Suriyawongpaisal, P, Sy, RG, Tai, ES, Tamosiunas, A, Tang, L, Tarawneh, M, Tarqui-Mamani, CB, Taylor, A, Theobald, H, Thijs, L, Thuesen, BH, Tolonen, HK, Tolstrup, JS, Topbas, M, Torrent, M, Traissac, P, Trinh, OT, Tulloch-Reid, MK, Tuomainen, TP, Turley, ML, Tzourio, C, Ueda, P, Ukoli, FA, Ulmer, H, Uusitalo, HM, Valdivia, G, Valvi, D, van Rossem, L, van Valkengoed, IG, Vanderschueren, D, Vanuzzo, D, Vega, T, Velasquez-Melendez, G, Veronesi, G, Verschuren, WM, Verstraeten, R, Viet, L, Vioque, J, Virtanen, JK, Visvikis-Siest, S, Viswanathan, B, Vollenweider, P, Voutilainen, S, Vrijheid, M, Wade, AN, Wagner, A, Walton, J, Wan Mohamud, WN, Wang, F, Wang, MD, Wang, Q, Wang, YX, Wannamethee, SG, Weerasekera, D, Whincup, PH, Widhalm, K, Wiecek, A, Wijga, AH, Wilks, RJ, Willeit, J, Wilsgaard, T, Wojtyniak, B, Wong, TY, Woo, J, Woodward, M, Wu, FC, Wu, SL, Xu, H, Yan, W, Yang, X, Ye, X, Yoshihara, A, Younger-Coleman, NO, Zambon, S, Zargar, AH, Zdrojewski, T, Zhao, W, Zheng, Y, and Zuñiga Cisneros, J

Published
2016
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9. Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331 288 participants

Author

Danaei, G, Fahimi, S, Lu, Y, Zhou, B, Hajifathalian, K, Di Cesare, M, Lo, WC, Reis-Santos, B, Cowan, MJ, Shaw, JE, Bentham, J, Lin, JK, Bixby, H, Magliano, D, Bovet, P, Miranda, JJ, Khang, YH, Stevens, GA, Riley, LM, Ali, MK, Ezzati, M, Abdeen, ZA, Kadir, KA, Abu-Rmeileh, M, Acosta-Cazares, B, Aekplakorn, W, Aguilar-Salinas, CA, Ahmadvand, A, Al Nsour, M, Alkerwi, A, Amouyel, P, Andersen, LB, Anderssen, SA, Andrade, DS, Anjana, RM, Aounallah-Skhiri, H, Aris, T, Arlappa, N, Arveiler, D, Assah, FK, Avdicová, M, Balakrishna, N, Bandosz, P, Barbagallo, CM, Barceló, A, Batieha, AM, Baur, LA, Ben Romdhane, H, Bernabe-Ortiz, A, Bhargava, SK, Bi, Y, Bjerregaard, P, Björkelund, C, Blake, M, Blokstra, A, Bo, S, Boehm, BO, Boissonnet, CP, Brajkovich, I, Breckenkamp, J, Brewster, LM, Brian, GR, Bruno, G, Bugge, A, Cabrera de León, A, Can, G, Cândido, AP, Capuano, V, Carvalho, MJ, Casanueva, FF, Caserta, CA, Castetbon, K, Chamukuttan, S, Chaturvedi, N, Chen, CJ, Chen, F, Chen, S, Cheng, CY, Chetrit, A, Chiou, ST, Cho, Y, Chudek, J, Cifkova, R, Claessens, F, Concin, H, Cooper, C, Cooper, R, Costanzo, S, Cottel, D, Cowell, C, Crujeiras, AB, D'Arrigo, G, Dallongeville, J, Dankner, R, Dauchet, L, de Gaetano, G, De Henauw, S, Deepa, M, Dehghan, A, Dhana, K, Di Castelnuovo, AF, Djalalinia, S, Doua, K, Drygas, W, Du, Y, Egbagbe, EE, Eggertsen, R, El Ati, J, Elosua, R, Erasmus, RT, Erem, C, Ergor, G, Eriksen, L, Escobedo-de la Peña, J, Fall, CH, Farzadfar, F, Felix-Redondo, FJ, Ferguson, TS, Fernández-Bergés, D, Ferrari, M, Ferreccio, C, Finn, JD, Föger, B, Foo, LH, Fouad, HM, Francis, DK, Franco Mdo, C, Frontera, G, Furusawa, T, Gaciong, Z, Galbarczyk, A, Garnett, SP, Gaspoz, JM, Gasull, M, Gates, L, Geleijnse, JM, Ghasemain, A, Giampaoli, S, Gianfagna, F, Giovannelli, J, Gonzalez Gross, M, González Rivas, JP, Gorbea, MB, Gottrand, F, Grant, JF, Grodzicki, T, Grøntved, A, Gruden, G, Gu, D, Guan, OP, Guerrero, R, Guessous, I, Guimaraes, AL, Gutierrez, L, Hardy, R, Hari Kumar, R, Heidemann, C, Hihtaniemi, IT, Ho, SY, Ho, SC, Hofman, A, Horimoto, AR, Hormiga, CM, Horta, BL, Houti, L, Hussieni, AS, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, AG, Ibrahim, MM, Ikeda, N, Ikram, MA, Irazola, VE, Islam, M, Iwasaki, M, Jacobs, JM, Jafar, T, Jasienska, G, Jiang, CQ, Jonas, JB, Joshi, P, Kafatos, A, Kalter-Leibovici, O, Kasaeian, A, Katz, J, Kaur, P, Kavousi, M, Kelishadi, R, Kengne, AP, Kersting, M, Khader, YS, Kiechl, S, Kim, J, Kiyohara, Y, Kolsteren, P, Korrovits, P, Koskinen, S, Kratzer, W, Kromhout, D, Kula, K, Kurjata, P, Kyobutungi, C, Lachat, C, Laid, Y, Lam, TH, Lanska, V, Lappas, G, Laxmaiah, A, Leclercq, C, Lee, J, Lehtimäki, T, Lekhraj, R, León-Muñoz, LM, Li, Y, Lim, WY, Lima-Costa, MF, Lin, HH, Lin, X, Lissner, L, Lorbeer, R, Lozano, JE, Lundqvist, A, Lytsy, P, Ma, G, Machado-Coelho, GL, Machi, S, Maggi, S, Makdisse, M, Mallikharjuna v, K, Manios, Y, Manzato, E, Margozzini, P, Marques-Vidal, P, Martorell, R, Masoodi, SR, Matsha, TE, Mbanya, JC, McFarlane, SR, McGarvey, ST, McLachlan, S, McNulty, BA, Mediene-Benchekor, S, Meirhaeghe, A, Menezes, AM, Merat, S, Meshram, II, Mi, J, Miquel, JF, Mohamed, MK, Mohammad, K, Mohan, V, Mohd Yusoff, MF, Møller, NC, Molnar, D, Mondo, CK, Moreno, LA, Morgan, K, Moschonis, G, Mossakowska, M, Mostafa, A, Mota, J, Muiesan, ML, Müller-Nurasyid, M, Mursu, J, Nagel, G, Námešná, J, Nang, EE, Nangia, VB, Navarrete-Muñoz, EM, Ndiaye, NC, Nervi, F, Nguyen, ND, Nieto-Martínez, RE, Alvarado, L, Ning, G, Ninomiya, T, Noale, M, Noto, D, Ochoa-Avilés, M, Oh, K, Onat, A, Osmond, C, Otero, JA, Palmieri, L, Panda-Jonas, S, Panza, F, Parsaeian, M, Peixoto, SV, Pereira, AC, Peters, A, Peykari, N, Pilav, A, Pitakaka, F, Piwonska, A, Piwonski, J, Plans-Rubió, P, Porta, M, Portegies, ML, Poustchi, H, Pradeepa, R, Price, JF, Punab, M, Qasrawi, RF, Qorbani, M, Raitakari, O, Ramachandra Rao, S, Ramachandran, A, Ramos, R, Rampal, S, Rathmann, W, Redon, J, Reganit, PF, Rigo, F, Robinson, SM, Robitaille, C, Rodríguez, LA, Rodríguez-Artalejo, F, del Cristo Rodriguez-Perez, M, Rojas-Martinez, R, Romaguera, D, Rosengren, A, Rubinstein, A, Rui, O, Ruiz-Betancourt, BS, Rutkowski, M, Sabanayagam, C, Sachdev, HS, Saidi, O, Sakarya, S, Salanave, B, Salonen, JT, Salvetti, M, Sánchez-Abanto, J, Santos, RN, Santos, R, Sardinha, LB, Scazufca, M, Schargrodsky, H, Scheidt-Nave, C, Shibuya, K, Shin, Y, Shiri, R, Siantar, R, Sibai, AM, Simon, M, Simons, J, Simons, LA, Sjostrom, M, Slowikowska-Hilczer, J, Slusarczyk, P, Smeeth, L, Snijder, MB, Solfrizzi, V, Sonestedt, E, Soumare, A, Staessen, JA, Steene-Johannessen, J, Stehle, P, Stein, AD, Stessman, J, Stöckl, D, Stokwiszewski, J, Strufaldi, MW, Sun, CA, Sundström, J, Suriyawongpaisal, P, Sy, RG, Tai, ES, Tarawneh, M, Tarqui-Mamani, CB, Thijs, L, Tolstrup, JS, Topbas, M, Torrent, M, Traissac, P, Trinh, OT, Tulloch-Reid, MK, Tuomainen, TP, Turley, ML, Tzourio, C, Ueda, P, Ukoli, FM, Ulmer, H, Valdivia, G, van Valkengoed, IG, Vanderschueren, D, Vanuzzo, D, Vega, T, Velasquez-Melendez, G, Veronesi, G, Verschuren, M, Vioque, J, Virtanen, J, Visvikis-Siest, S, Viswanathan, B, Vollenweider, P, Voutilainen, S, Wade, AN, Wagner, A, Walton, J, Mohamud, WN, Wang, MD, Wang, YX, Wannamethee, SG, Weerasekera, D, Whincup, PH, Widhalm, K, Wiecek, A, Wilks, RJ, Willeit, J, Wojtyniak, B, Wong, TY, Woo, J, Woodward, M, Wu, AG, Wu, FC, Wu, SL, Xu, H, Yang, X, Ye, X, Yoshihara, A, Younger-Coleman, NO, Zambon, S, Zargar, AH, Zdrojewski, T, Zhao, W, and Zheng, Y

Published
2015
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15. Ultra-processed foods consumption and diet quality of European children, adolescents and adults: Results from the I.Family study

Author

Lauria, F., Dello Russo, M., Formisano, A., De Henauw, S., Hebestreit, A., Hunsberger, M., Krogh, Vittorio, Intemann, T., Lissner, L., Molnar, D., Moreno, L.A., Reisch, L.A., Tornaritis, M., Veidebaum, T., Williams, G., Siani, A., Russo, P., and consortium, I.Family

Subjects
Adult, Male, Nova classification, Calorie, Adolescent, Food Handling, Adolescent Nutritional Physiological Phenomena, Endocrinology, Diabetes and Metabolism, Saturated fat, Health Behavior, Population, Child Behavior, Nutritional Status, Medicine (miscellaneous), Recommended Dietary Allowances, Adolescents, Diet Surveys, Young Adult, Environmental health, Ultra-processed foods, Humans, Adults, Medicine, Child, education, Children, Consumption (economics), education.field_of_study, Nutrition and Dietetics, business.industry, Age Factors, Feeding Behavior, Diet, Europe, Diet quality, Adolescent Behavior, Food processing, Fast Foods, Food systems, Early adolescents, Female, Child Nutritional Physiological Phenomena, Energy Intake, Cardiology and Cardiovascular Medicine, business, Nutritive Value
Abstract

Background and aims Food processing has been indicated as a factor capable of negatively affecting the global food system, including the profile of consumers’ diets. The objectives of the present study were to provide a description of the consumption of ultra-processed foods (UPFs) in the large population of children, adolescents and adults from eight European countries participating to the I.Family study, and to investigate the association between UPFs intake and nutritional quality of the diet. Methods and results Dietary intake was assessed using a 24-h dietary recall. The quality of the diet was evaluated by the Healthy Dietary Adherence Score (HDAS) using an FFQ. UPFs were classified according to the NOVA classification. Almost half of the daily energy intake of the 7073 participants came from UPFs, and this trend decreased progressively with age. UPFs contributed more than 50 % of the daily intake of total and saturated fat, carbohydrates and about 70 % of sugars intake in children and adolescents. No differences in UPFs consumption were found according to the educational and socio-economic status of the population. Energy intake increased across the quintiles of UPFs intake, while HDAS decreased. The frequency of consumption of fruit and vegetable, fish, and fibre rich foods was low in the fifth quintile of UPFs intake, both in adolescents and in adults. The consumption of foods rich in calories and low in nutritional content, operationally defined as “junk food”, was significantly higher in the fifth quintile. Conclusions In the population of the European I.Family study, UPFs contributed a large proportion of the daily energy intake, especially in children and adolescents. Higher consumption of UPFs was associated with a lower quality of the diet. Registration number for clinical trials ISRCTN62310987.

Published
2021

21. Internal exposure of Flemish teenagers to environmental pollutants: Results of the Flemish Environment and Health Study 2016–2020 (FLEHS IV)

Author

Schoeters, G., primary, Verheyen, V.J., additional, Colles, A., additional, Remy, S., additional, Martin, L. Rodriguez, additional, Govarts, E., additional, Nelen, V., additional, Den Hond, E., additional, De Decker, A., additional, Franken, C., additional, Loots, I., additional, Coertjens, D., additional, Morrens, B., additional, Bastiaensen, M., additional, Gys, C., additional, Malarvannan, G., additional, Covaci, A., additional, Nawrot, T., additional, De Henauw, S., additional, Bellemans, M., additional, Leermakers, M., additional, Van Larebeke, N., additional, Baeyens, W., additional, Jacobs, G., additional, Voorspoels, S., additional, Nielsen, F., additional, and Bruckers, L., additional

Published
2022
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22. Prospective BMI changes in preschool children are not effected by changes in EBRBs but by parental characteristics and body weight perceptions: The ToyBox-study

Author

Manios Y., Lambert K.A., Karaglani E., Mavrogianni C., Moreno L.A., Iotova V., Swiader-Lesniak A., Koletzko B., Cardon G., Androutsos O., Moschonis G., de Bourdeaudhuij I., Paw M.C.A., Summerbell C., Lobstein T., Annemans L., Buijs G., Reilly J., Swinburn B., Ward D., Grammatikaki E., Katsarou C., Apostolidou E., Livaniou A., Lymperopoulou K., Efstathopoulou E., Lambrinou C.-P., Giannopoulou A., Siatitsa E., Argiri E., Maragkopoulou K., Douligeris A., Duvinage K., Ibrügger S., Strauß A., Herbert B., Birnbaum J., Payr A., Geyer C., de Craemer M., de Decker E., de Henauw S., Maes L., Vereecken C., van Assche J., Pil L., te Velde S., Moreno L., Mouratidou T., Fernandez J., Mesana M., de Miguel-Etayo P., González-Gil E.M., Gracia-Marco L., Oves B., Yngve A., Kugelberg S., Lynch C., Mosdøl A., Nilsen B.B., Moore H., Douthwaite W., Nixon C., Kreichauf S., Wildgruber A., Socha P., Kulaga Z., Zych K., Gózdz M., Gurzkowska B., Szott K., Lateva M., Usheva N., Galcheva S., Marinova V., Radkova Z., Feschieva N., Aikenhead A., Dorgelo A., Nethe A., Jansen J., Gmeiner O., Retterath J., Wildeis J., Günthersberger A., Gibson L., Voegele C., and ToyBox Study Group

Abstract

Objective: To examine the effect of the intervention implemented in the ToyBox study on changes observed in age and sex specific BMI percentile and investigate the role of perinatal factors, parental perceptions and characteristics on this change. Design: A multicomponent, kindergarten-based, family-involved intervention with a cluster-randomized design. A standardized protocol was used to measure children’s body weight and height. Information was also collected from parents/caregivers via the use of validated questionnaires. Linear mixed effect models with random intercept for country, socioeconomic status and school were used. Setting: Selected preschools within the provinces of Oost-Flanders and West-Flanders (Belgium), Varna (Bulgaria), Bavaria (Germany), Attica (Greece), Mazowieckie (Poland) and Zaragoza (Spain). Participants: A sample of 6, 268 pre-schoolers aged 3.5-5.5 (51.9% boys). Results: There was no intervention effect on the change in children’s BMI percentile. However, parents’ underestimation of their children’s actual weight status, parental overweight and mothers’ pre-pregnancy overweight/obesity were found to be significantly and independently associated with increases in children’s BMI percentile in multivariate modelling. Conclusion: Before or as part of the implementation of any childhood obesity intervention initiative, it is important to assist parents/caregivers to correctly perceive their own and their children’s weight status. Recognition of excessive weight by parents/caregivers can increase their readiness to change and as such facilitate higher adherence to favourable behavioural changes within the family. © 2021 Lippincott Williams and Wilkins. All rights reserved.

Published
2022

23. Safety of an aqueous ethanolic extract of Labisia pumila as a novel food pursuant to Regulation (EU) 2015/2283

Author

Turck, D., Bohn, T., Castenmiller, J., De Henauw, S., Hirsch-Ernst, K. I., Maciuk, A., Mangelsdorf, I., Mcardle, H. J., Naska, A., Pelaez, C., Pentieva, K., Siani, A., Thies, F., Tsabouri, S., Vinceti, M., Cubadda, F., Frenzel, T., Heinonen, M., Maradona, M. P., Marchelli, R., Neuhauser-Berthold, M., Poulsen, M., Schlatter, J. R., Albert, O., Matijevic, L., and Knutsen, H. K.

Subjects
safety, food supplement, Veterinary (miscellaneous), Animal Science and Zoology, Parasitology, Plant Science, aqueous ethanolic extract of Labisia pumila, novel food, Microbiology, Food Science
Published
2022

24. Prospective BMI changes in preschool children are associated with parental characteristics and body weight perceptions: the ToyBox-study

Author

Manios, Y, Lambert, Katrina, Karaglani, E, Mavrogianni, C, Moreno, LA, Iotova, V, Świąder-Leśniak, A, Koletzko, B, Cardon, G, Androutsos, O, Moschonis, George, de Bourdeaudhuij, I, Paw, MCA, Summerbell, C, Lobstein, T, Annemans, L, Buijs, G, Reilly, J, Swinburn, B, Ward, D, Grammatikaki, E, Katsarou, C, Apostolidou, E, Livaniou, A, Lymperopoulou, K, Efstathopoulou, E, Lambrinou, CP, Giannopoulou, A, Siatitsa, E, Argiri, E, Maragkopoulou, K, Douligeris, A, Duvinage, K, Ibrügger, S, Strauß, A, Herbert, B, Birnbaum, J, Payr, A, Geyer, C, de Craemer, M, de Decker, E, de Henauw, S, Maes, L, Vereecken, C, van Assche, J, Pil, L, Velde, S te, Mouratidou, T, Fernandez, J, Mesana, M, de Miguel-Etayo, P, González-Gil, EM, Gracia-Marco, L, Oves, B, Yngve, A, Kugelberg, S, Lynch, C, Mosdøl, A, Nilsen, BB, Moore, H, Douthwaite, W, Nixon, C, Kreichauf, S, Wildgruber, A, Socha, P, Kulaga, Z, Zych, K, Góźdź, M, Gurzkowska, B, Szott, K, Lateva, M, Usheva, N, Galcheva, S, Marinova, V, Radkova, Z, Feschieva, N, Aikenhead, A, Dorgelo, A, Nethe, A, Jansen, J, Gmeiner, O, Retterath, J, Wildeis, J, Günthersberger, A, Gibson, L, and Voegele, C

Subjects
111712 Health Promotion, 111707 Family Care, FOS: Health sciences, 111704 Community Child Health
Abstract

Objective: To examine the effect of the intervention implemented in the ToyBox study on changes observed in age and sex specific BMI percentile and investigate the role of perinatal factors, parental perceptions and characteristics on this change. Design: A multicomponent, kindergarten-based, family-involved intervention with a cluster-randomized design. A standardized protocol was used to measure children’s body weight and height. Information was also collected from parents/caregivers via the use of validated questionnaires. Linear mixed effect models with random intercept for country, socioeconomic status and school were used. Setting: Selected preschools within the provinces of Oost-Flanders and West-Flanders (Belgium), Varna (Bulgaria), Bavaria (Germany), Attica (Greece), Mazowieckie (Poland) and Zaragoza (Spain). Participants: A sample of 6,268 pre-schoolers aged 3.5-5.5 (51.9% boys). Results: There was no intervention effect on the change in children’s BMI percentile. However, parents’ underestimation of their children’s actual weight status, parental overweight and mothers’ pre-pregnancy overweight/obesity were found to be significantly and independently associated with increases in children’s BMI percentile in multivariate modelling. Conclusion: Before or as part of the implementation of any childhood obesity intervention initiative, it is important to assist parents/caregivers to correctly perceive their own and their children’s weight status. Recognition of excessive weight by parents/caregivers can increase their readiness to change and as such facilitate higher adherence to favourable behavioural changes within the family.

Published
2022
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25. Inflammation profile in overweight/obese adolescents in Europe: an analysis in relation to iron status

Author

Ferrari, M., Cuenca-Garcia, M., Valtuena, J., Moreno, L.A., Censi, L., Gonzalez-Gross, M., Androutsos, O., Gilbert, C.C., Huybrechts, I., Dallongeville, J., Sjostrom, M., Molnar, D., De Henauw, S., Gomez-Martinez, S., de Moraes, A.C.F., Kafatos, A., Widhalm, K., and Leclercq, C.

Subjects
Obesity -- Physiological aspects, Inflammation -- Physiological aspects, Food/cooking/nutrition, Health
Abstract

BACKGROUND/OBJECTIVES: The objectives of this study were to investigate the relationship between inflammatory parameters (CRP, c-reactive protein; AGP, [alpha]1-acid glycoprotein), iron status indicators (SF, serum ferritin; sTfR, soluble transferrin receptor) and body mass index (BMI) z-score, fat-free mass (FFM) and fat mass (FM) in European adolescents. Differences in intake for some nutrients (total iron, haem and non-haem iron, vitamin C, calcium, proteins) were assessed according to BMI categories, and the association of nutrient intakes with BMI z-score, FM and FFM was evaluated. METHODS: A total of 876 adolescents participating in the Healthy Lifestyle in Europe by Nutrition in Adolescence-Cross Sectional Study were included in the study sample. RESULTS: Mean CRP values (standard error; s.e.) were significantly higher in overweight/obese adolescents (1.7 [+ or - ] 0.3 and 1.4 [+ or -] 0.3 mg/l in boys and girls, respectively) than in thin/normal-weight adolescents (1.1 [+ or -] 0.2 and 1.0 [+ or -]0.1 mg/l in boys and girls, respectively) (P < 0.05). For boys, mean SF values (s.e.) were significantly higher in overweight/obese adolescents (46.9 [+ or -] 2.7 [micro]g/l) than in thin/normal-weight adolescents (35.7 [+ or -] 1.7 [micro]g/l) (P < 0.001), whereas median sTfR values did not differ among BMI categories for both boys and girls. Multilevel regression analyses showed that BMI z-score and FM were significantly related to CRP and AGP (P < 0.05). Dietary variables did not differ significantly among BMI categories, except for the intake of vegetable proteins, which, for boys, was higher in thin/normal-weight adolescents than in overweight/obese adolescents (P < 0.05). CONCLUSIONS: The adiposity of the European adolescents was sufficient to cause chronic inflammation but not sufficient to impair iron status and cause iron deficiency. European Journal of Clinical Nutrition (2015) 69, 247-255; doi:10.1038/ejcn.2014.154; published online 10 September 2014, INTRODUCTION There is growing evidence that obesity is characterised by a chronic, low-grade, systemic inflammation (1, 2) that may have a causal role in the development of several diseases such [...]

Published
2015
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27. How do energy balance-related behaviors cluster in adolescents?

Author

Collese, Tatiana Sadalla, De Moraes, Augusto César Ferreira, Fernández-Alvira, Juan Miguel, Michels, Nathalie, De Henauw, Stefaan, Manios, Yannis, Androutsos, Odysseas, Kafatos, Anthony, Widhalm, Kurt, Galfo, Myriam, Beghin, Laurent, Sjöström, Michael, Pedrero-Chamizo, Raquel, Carvalho, Heráclito Barbosa, Moreno, Luis A., Moreno, L. A., Gottrand, F., De Henauw, S., González-Gross, M., Gilbert, C., Kafatos, A., Libersa, C., Sánchez, J., Kersting, M., Sjöstrom, M., Molnár, D., Dallongeville, J., Hall, G., Maes, L., Scalfi, L., Meléndez, P., Fleta, J., Casajús, J. A., Rodríguez, G., Tomás, C., Mesana, M. I., Vicente-Rodríguez, G., Villarroya, A., Gil, C. M., Ara, I., Revenga, J., Lachen, C., Fernández Alvira, J., Bueno, G., Lázaro, A., Bueno, O., León, J. F., Garagorri, J. M., Bueno, M., Iglesia, I., Velasco, P., Bel, S., Gracia-Marco, L., Mouratidou, T., Marcos, A., Wärnberg, J., Nova, E., Gómez, S., Ligia Díaz, E., Romeo, J., Veses, A., Puertollano, M. Angeles, Zapatera, B., Pozo, T., Beghin, L., Iliescu, C., Von Berlepsch, J., Sichert-Hellert, W., Koeppen, E., Molnar, D., Erhardt, E., Csernus, K., Török, K., Bokor, S., Angster, null, Nagy, E., Kovács, O., Répasi, J., Codrington, C., Plada, M., Papadaki, A., Sarri, K., Viskadourou, A., Hatzis, C., Kiriakakis, M., Tsibinos, G., Vardavas, C., Sbokos, M., Protoyeraki, E., Fasoulaki, M., Stehle, P., Pietrzik, K., Breidenassel, C., Spinneker, A., Al-Tahan, J., Segoviano, M., Berchtold, A., Bierschbach, C., Blatzheim, E., Schuch, A., Pickert, P., Castillo, M. J., Gutiérrez, A., Ortega, F. B., Ruiz, J. R., Artero, E. G., España, V., Jiménez-Pavón, D., Chillón, P., Sánchez-Muñoz, C., Cuenca, M., Arcella, D., Azzini, E., Barrison, E., Bevilacqua, N., Buonocore, P., Catasta, G., Censi, L., Ciarapica, D., D’Acapito, P., Ferrari, M., Galfo, M., Le Donne, C., Leclercq, C., Maiani, G., Mauro, B., Mistura, L., Pasquali, A., Piccinelli, R., Polito, A., Spada, R., Sette, S., Zaccaria, M., Vitaglione, P., Montagnese, C., De Bourdeaudhuij, I., De Vriendt, T., Matthys, C., Vereecken, C., de Maeyer, M., Ottevaere, C., Huybrechts, I., Widhalm, K., Phillipp, K., Dietrich, S., Kubelka, B., Boriss-Riedl, M., Manios, Y., Grammatikaki, E., Bouloubasi, Z., Louisa Cook, T., Eleutheriou, S., Consta, O., Moschonis, G., Katsaroli, I., Kraniou, G., Papoutsou, S., Keke, D., Petraki, I., Bellou, E., Tanagra, S., Kallianoti, K., Argyropoulou, D., Kondaki, K., Tsikrika, S., Karaiskos, C., Meirhaeghe, A., Sjöström, M., Hagströmer, M., Hallström, L., Patterson, E., Kwak, L., Rizzo, N., Hurtig Wennlöf, A., Sánchez-Molero, J., Picó, E., Navarro, M., Viadel, B., Carreres, J. E., Merino, G., Sanjuán, R., Lorente, M., Sánchez, M. J., Castelló, S., Thomas, S., Allchurch, E., Burguess, P., Astrom, A., Sverkén, A., Broberg, A., Masson, A., Lehoux, C., Brabant, P., Pate, P., Fontaine, L., Sebok, A., Kuti, T., Hegyi, A., Maldonado, C., Llorente, A., García, E., von Fircks, H., Lilja Hallberg, M., Messerer, M., Larsson, M., Fredriksson, H., Adamsson, V., Börjesson, I., Fernández, L., Smillie, L., Wills, J., Valtueña, Jara, Albers, Ulrike, Pedrero, Raquel, Palacios, Gonzalo, Meléndez, Agustín, Benito, Pedro J., Lorente, Juan José Gómez, Cañada, David, Urzanqui, Alejandro, Ortiz, Juan Carlos, Fuentes, Francisco, Torres, Rosa María, Navarro, Paloma, Collese, Tatiana Sadalla, De Moraes, Augusto César Ferreira, Fernández-Alvira, Juan Miguel, Michels, Nathalie, De Henauw, Stefaan, Manios, Yanni, Androutsos, Odyssea, Kafatos, Anthony, Widhalm, Kurt, Galfo, Myriam, Beghin, Laurent, Sjöström, Michael, Pedrero-Chamizo, Raquel, Carvalho, Heráclito Barbosa, Moreno, Luis A., Moreno, L. A., Gottrand, F., De Henauw, S., González-Gross, M., Gilbert, C., Kafatos, A., Libersa, C., Sánchez, J., Kersting, M., Sjöstrom, M., Molnár, D., Dallongeville, J., Hall, G., Maes, L., Scalfi, L., Meléndez, P., Fleta, J., Casajús, J. A., Rodríguez, G., Tomás, C., Mesana, M. I., Vicente-Rodríguez, G., Villarroya, A., Gil, C. M., Ara, I., Revenga, J., Lachen, C., Fernández Alvira, J., Bueno, G., Lázaro, A., Bueno, O., León, J. F., Garagorri, J. M., Bueno, M., Iglesia, I., Velasco, P., Bel, S., Gracia-Marco, L., Mouratidou, T., Marcos, A., Wärnberg, J., Nova, E., Gómez, S., Ligia Díaz, E., Romeo, J., Veses, A., Puertollano, M. Angele, Zapatera, B., Pozo, T., Beghin, L., Iliescu, C., Von Berlepsch, J., Sichert-Hellert, W., Koeppen, E., Molnar, D., Erhardt, E., Csernus, K., Török, K., Bokor, S., Angster, Null, Nagy, E., Kovács, O., Répasi, J., Codrington, C., Plada, M., Papadaki, A., Sarri, K., Viskadourou, A., Hatzis, C., Kiriakakis, M., Tsibinos, G., Vardavas, C., Sbokos, M., Protoyeraki, E., Fasoulaki, M., Stehle, P., Pietrzik, K., Breidenassel, C., Spinneker, A., Al-Tahan, J., Segoviano, M., Berchtold, A., Bierschbach, C., Blatzheim, E., Schuch, A., Pickert, P., Castillo, M. J., Gutiérrez, A., Ortega, F. B., Ruiz, J. R., Artero, E. G., España, V., Jiménez-Pavón, D., Chillón, P., Sánchez-Muñoz, C., Cuenca, M., Arcella, D., Azzini, E., Barrison, E., Bevilacqua, N., Buonocore, P., Catasta, G., Censi, L., Ciarapica, D., D’Acapito, P., Ferrari, M., Galfo, M., Le Donne, C., Leclercq, C., Maiani, G., Mauro, B., Mistura, L., Pasquali, A., Piccinelli, R., Polito, A., Spada, R., Sette, S., Zaccaria, M., Vitaglione, P., Montagnese, C., De Bourdeaudhuij, I., De Vriendt, T., Matthys, C., Vereecken, C., de Maeyer, M., Ottevaere, C., Huybrechts, I., Widhalm, K., Phillipp, K., Dietrich, S., Kubelka, B., Boriss-Riedl, M., Manios, Y., Grammatikaki, E., Bouloubasi, Z., Louisa Cook, T., Eleutheriou, S., Consta, O., Moschonis, G., Katsaroli, I., Kraniou, G., Papoutsou, S., Keke, D., Petraki, I., Bellou, E., Tanagra, S., Kallianoti, K., Argyropoulou, D., Kondaki, K., Tsikrika, S., Karaiskos, C., Meirhaeghe, A., Sjöström, M., Hagströmer, M., Hallström, L., Patterson, E., Kwak, L., Rizzo, N., Hurtig Wennlöf, A., Sánchez-Molero, J., Picó, E., Navarro, M., Viadel, B., Carreres, J. E., Merino, G., Sanjuán, R., Lorente, M., Sánchez, M. J., Castelló, S., Thomas, S., Allchurch, E., Burguess, P., Astrom, A., Sverkén, A., Broberg, A., Masson, A., Lehoux, C., Brabant, P., Pate, P., Fontaine, L., Sebok, A., Kuti, T., Hegyi, A., Maldonado, C., Llorente, A., García, E., von Fircks, H., Lilja Hallberg, M., Messerer, M., Larsson, M., Fredriksson, H., Adamsson, V., Börjesson, I., Fernández, L., Smillie, L., Wills, J., Valtueña, Jara, Albers, Ulrike, Pedrero, Raquel, Palacios, Gonzalo, Meléndez, Agustín, Benito, Pedro J., Lorente, Juan José Gómez, Cañada, David, Urzanqui, Alejandro, Ortiz, Juan Carlo, Fuentes, Francisco, Torres, Rosa María, Navarro, Paloma, Lille Inflammation Research International Center - U 995 (LIRIC), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Inserm, Université de Lille, CHU Lille, and Lille Inflammation Research International Center - U 995 [LIRIC]

Subjects
Male, medicine.medical_specialty, Parental education, Health (social science), Adolescent, Healthy eating, Disease cluster, socioeconomic status, parental education, 03 medical and health sciences, Screen time, 0302 clinical medicine, energy balance-related behaviors, Surveys and Questionnaires, Environmental health, [SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], medicine, Cluster Analysis, Humans, Socioeconomic statu, adolescents, Cluster analysi, 030212 general & internal medicine, Exercise, Socioeconomic status, [SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics, 030505 public health, 4. Education, Public health, Public Health, Environmental and Occupational Health, Feeding Behavior, Sedentary behavior, Country of origin, Cross-Sectional Studies, Social Class, Adolescent Behavior, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Female, Sedentary Behavior, Energy Metabolism, 0305 other medical science, Psychology, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, Brazil, Energy balance-related behavior
Abstract

International audience; OBJECTIVES: To delineate the clustering of energy balance-related behaviors in adolescents and investigate whether these behaviors are associated with the household socioeconomic status and parental education level. METHODS: Two cross-sectional studies assessed information on sedentary behavior, physical activity, sugar-sweetened beverages and fruit and vegetable consumption, and sleep duration by self-reported questionnaires in adolescents (12.5-17.5 years old) from Maringa/Brazil (BRACAH Study; n = 682) and ten European cities (HELENA Study; n = 1252) from nine different countries. Gender-specific cluster analyses were performed separately for each study, applying a combination of hierarchical and non-hierarchical methods. RESULTS: Girls showed equivalent behaviors: Sedentary; Active; Unhealthy Eating; Healthy Eating; while boys differed (Brazilian: Sedentary; Active; Healthy Eating; European: Sedentary; Healthy; Unhealthy Eating). In Brazil, we found no association between socioeconomic status and parental education. In European girls, the high socioeconomic status and both parents' university degree were associated with Healthy Eating. In European boys, the high socioeconomic status was associated with Unhealthy Eating, and the mothers' university degree was associated with the Healthy cluster. CONCLUSIONS: Adolescents show Sedentary behavior, regardless of their sex, country of origin, or socioeconomic condition.

Published
2018

32. Safety of frozen and dried formulations from whole house crickets (Acheta domesticus) as a Novel food pursuant to Regulation (EU) 2015/2283

Author

EFSA Panel on Nutrition, Novel Foods, Food Allergens (NDA), Turck D., Bohn T., Castenmiller J., De Henauw S., Hirsch-Ernst K.I., Maciuk A., Mangelsdorf I., McArdle H.J., Naska A., Pelaez C., Pentieva K., Siani A., Thies F., Tsabouri S., Vinceti M., Cubadda F., Frenzel T., Heinonen M., Marchelli R., Neuhauser-Berthold M., Poulsen M., Prieto Maradona M., Schlatter J.R., van Loveren H., Goumperis T., and Knutsen H.K.

Subjects
Acheta domesticus, Veterinary (miscellaneous), Population, insect powder, Novel food, Nutri1010, TP1-1185, Plant Science, Target population, medicine.disease_cause, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Ingredient, 0404 agricultural biotechnology, Chitin, medicine, TX341-641, Food science, education, 030304 developmental biology, 2. Zero hunger, 0303 health sciences, education.field_of_study, Novel Foods, biology, Nutrition. Foods and food supply, business.industry, Chemical technology, 04 agricultural and veterinary sciences, biology.organism_classification, Food safety, 040401 food science, food safety, Scientific Opinion, chemistry, Acheta, house cricket, Animal Science and Zoology, Parasitology, business, Genotoxicity, Food Science
Abstract

Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Food and Food Allergens (NDA) was asked to deliver an opinion on the safety of frozen and dried formulations from house crickets (Acheta domesticus) as a novel food pursuant to Regulation (EU) 2015/2283. The NF is proposed in three formulations: (i) frozen, (ii) dried, (iii) ground. The main components of the NF are protein, fat and fibre (chitin) in the dried form of the NF, and water, protein, fat and fibre (chitin) in the frozen form of the NF. The Panel notes that the concentrations of contaminants in the NF depend on the occurrence levels of these substances in the insect feed. The Panel further notes that there are no safety concerns regarding the stability of the NF if the NF complies with the proposed specification limits during its entire shelf‐life. The NF has a high‐protein content, although the true protein levels in the NF are overestimated when using the nitrogen‐to‐protein conversion factor of 6.25, due to the presence of non‐protein nitrogen from chitin. The applicant proposed to use the NF in the form of a snack, and as a food ingredient in a number of food products. The target population proposed by the applicant is the general population. The Panel notes that, considering the composition of the NF and the proposed conditions of use, the consumption of the NF is not nutritionally disadvantageous. The Panel notes that no genotoxicity and no subchronic toxicity studies with the NF were provided by the applicant. Considering that no safety concerns arise from the history of use of A. domesticus or from the compositional data of the NF, the Panel identified no other safety concerns than allergenicity. The Panel considers that the consumption of the NF might trigger primary sensitisation to A. domesticus proteins and may cause allergic reactions in subjects allergic to crustaceans, mites and molluscs. Additionally, allergens from the feed may end up in the NF. The Panel concludes that the NF is safe under the proposed uses and use levels.

Published
2021

33. Safety of frozen and dried formulations from whole yellow mealworm (Tenebrio molitor larva) as a novel food pursuant to Regulation (EU) 2015/2283

Author

EFSA Panel on Nutrition, Novel Foods, Food Allergens (NDA), Turck D., Bohn T., Castenmiller J., De Henauw S., Hirsch-Ernst K.I., Maciuk A., Mangelsdorf I., McArdle H.J., Naska A., Pelaez C., Pentieva K., Siani A., Thies F., Tsabouri S., Vinceti M., Cubadda F., Frenzel T., Heinonen M., Marchelli R., Neuhauser-Berthold M., Poulsen M., Prieto Maradona M., Schlatter J.R., van Loveren H., Ververis E., and Knutsen H.K.

Subjects
Agriculture and Food Sciences, 0106 biological sciences, Entomophagy, Mealworm, Novel foods, Veterinary (miscellaneous), INSECTS, yellow mealworm, insect powder, Nutri1010, Novel food, TP1-1185, novel foods, Plant Science, 01 natural sciences, Microbiology, ENTOMOPHAGY, SECRETIONS, CADMIUM, 03 medical and health sciences, CYTOTOXIC MOLECULES, TX341-641, Food science, entomophagy, 030304 developmental biology, 2. Zero hunger, 0303 health sciences, Larva, biology, Nutrition. Foods and food supply, business.industry, Chemical technology, Biology and Life Sciences, biology.organism_classification, Food safety, food safety, 010602 entomology, Scientific Opinion, Tenebrio molitor larva, COLEOPTERA, Animal Science and Zoology, Parasitology, CHITIN, business, MELANOGENESIS, Food Science
Abstract

Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on frozen and dried formulations from whole yellow mealworm (Tenebrio molitor larva) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The term yellow mealworm refers to the larval form of the insect species Tenebrio molitor. The NF comprises the frozen and freeze-dried formulations of the yellow mealworm, whole or in the form of powder. The frozen formulation consists mainly of water, crude protein and fat whereas the freeze-dried formulations of crude protein, fat, digestible carbohydrates and fibre (chitin). The Panel notes that the levels of contaminants in the NF depend on the occurrence levels of these substances in the insect feed. The Panel notes furthermore that there are no safety concerns regarding the stability of the NF if the NF complies with the proposed specification limits during its entire shelf-life. The dried formulations of the NF have a high protein content, although the true protein levels in the NF are overestimated when using the nitrogen-to-protein conversion factor of 6.25, due to the presence of non-protein nitrogen from chitin. The applicant proposed to use the NF as whole frozen or whole dried insect, or in the form of powder, added as an ingredient to various food products such as cereal bars, pasta, meat imitates and bakery products. The target population is the general population. The Panel notes that, considering that the NF will not be the sole source of dietary protein, and the composition of the NF and the proposed conditions of use, the consumption of the NF is not nutritionally disadvantageous. The submitted toxicity studies from the literature did not raise safety concerns. The Panel considers that the consumption of the NF may induce primary sensitisation and allergic reactions to yellow mealworm proteins and may cause allergic reactions in subjects with allergy to crustaceans and dust mites. Additionally, allergens from the feed may end up in the NF. The Panel concludes that the NF is safe under the proposed uses and use levels. (C) 2021 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority.

Published
2021

34. European children's sugar intake on weekdays versus weekends: the IDEFICS study

Author

Svensson, A., Larsson, C., Eiben, G., Lanfer, A., Pala, V., Hebestreit, A., Huybrechts, I., Fernandez-Alvira, J.M., Russo, P., Koni, A.C., De Henauw, S., Veidebaum, T., Molnar, D., and Lissner, L.

Subjects
Medical research, Medicine, Experimental, Children -- Health aspects, Sugar -- Health aspects -- Demographic aspects, Food/cooking/nutrition, Health
Abstract

OBJECTIVES: To compare the intake of total sugars, foods and drinks rich in added sugar, and energy in children on weekdays (Monday-Thursday), Fridays and weekends. METHODS: Dietary intake (g, kJ, energy %) was assessed using a computerized 24-h recall method in a sample of 2- to 9-year-old children from Belgium, Cyprus, Estonia, Germany, Hungary, Italy, Spain and Sweden who were participating in the IDEFICS baseline study (2007-2008). Analyses were performed in 9497 children by selecting one 24-h recall per child (for comparison of weekdays vs weekends, and Fridays vs weekdays and weekends). Selected stratified analyses were performed by country and age group. RESULTS: Intake of total sugars exceeded 20 energy % in all countries but one. In the non-stratified analyses, the intakes of total sugars and foods and drinks rich in added sugar were found to be higher on weekends compared with weekdays (both P < 0.001), and intakes on Fridays were a mix between intakes on weekdays and weekends. Energy intake did not differ between weekdays and weekends. Results were somewhat heterogeneous, both across countries and age groups. CONCLUSIONS: High intake of sugar remains an important nutritional problem in children of many European countries. Interventions aiming to prevent this diet pattern may optimize their impact by targeting dietary habits on Fridays and weekends. Furthermore, when conducting dietary assessment in children, data from weekends and Fridays in combination with a selection of Mondays to Thursdays are needed to capture habitual sugar intake. Age and dietary cultures should also be considered in dietary intervention and assessment as effect modifications were seen for both age and country. doi:10.1038/ejcn.2014.87; published online 14 May 2014, INTRODUCTION There is currently no common European recommendation for sugar intake. (1) However, reducing the amount of sugar consumed is one of the most important dietary interventions to improve childhood [...]

Published
2014
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48. Safety of the extension of use of galacto-oligosaccharides as a Novel food pursuant to Regulation (EU) 2015/2283

Author

EFSA Panel on Nutrition, Novel Foods, Food Allergens (NDA), Turck D., Bohn T., Castenmiller J., De Henauw S., Hirsch-Ernst K.I., Maciuk A., Mangelsdorf I., McArdle H.J., Naska A., Pelaez C., Pentieva K., Siani A., Thies F., Tsabouri S., Vinceti M., Cubadda F., Frenzel T., Heinonen M., Marchelli R., Neuhauser-Berthold M., Poulsen M., Prieto Maradona M., Schlatter J.R., van Loveren H., Colombo P., and Knutsen H.K.

Subjects
Agriculture and Food Sciences, Veterinary (miscellaneous), Novel food, Nutri1010, TP1-1185, Plant Science, 010501 environmental sciences, Galacto-oligosaccharides, 01 natural sciences, Microbiology, Medicine and Health Sciences, TX341-641, Food science, 0105 earth and related environmental sciences, novel food, HUMAN-MILK, 2. Zero hunger, extension of use, Nutrition. Foods and food supply, Galacto‐oligosaccharides, Chemical technology, dietary fibre, GOS, 0402 animal and dairy science, Dietary fibre, 04 agricultural and veterinary sciences, Extension (predicate logic), dietary fiber, 040201 dairy & animal science, Scientific Opinion, Food supplement, food supplement, Animal Science and Zoology, Parasitology, Business, Food Science
Abstract

Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the extension of use of galacto-oligosaccharides (GOS) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is a syrup containing >= 57% w/w GOS (w/w dry matter), consisting of different galactosyl residues linked to a terminal glucose by a beta-glycosidic bond and also containing lactose and the constituent monomers of lactose (galactose and glucose). The NF is already authorised and included in the Union list of NFs and is produced according to the same production process. This application is limited to an assessment of the extension of use as a food ingredient in dairy confectionary, cheese and processed cheese, butter and spreads. There is a 10-30% increase in total GOS intake from the requested extension of use compared to the currently authorised uses at the highest 95th percentile. It is noted that the total intake at the highest mean (8.7-22.0 g/day) is below the adequate intake (AI) of 25 g/day for dietary fibre set to ensure a normal laxation in adults, while the highest 95th percentile (27.2-41.6 g/day) is higher than the AI. When the maximum use as a food supplement is added to the highest 95th percentile combined intake from all proposed and authorised food categories a total intake up to 58 g GOS/day is estimated. This highest intake level would exceed the AI for dietary fibre; however, no tolerable upper intake level for dietary fibre has been set and only transient gastrointestinal symptoms may be related to high intake of fibre. The Panel concludes that the NF, that is composed of >= 57% GOS dry matter, lactose and related saccharides, is safe under the proposed extension of use. (C) 2021 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority.

Published
2021

49. Safety of mung bean protein as a novel food pursuant to Regulation (EU) 2015/2283

Author

EFSA Panel on Nutrition, Novel Foods, Food Allergens (NDA), Turck D., Bohn T., Castenmiller J., De Henauw S., Hirsch-Ernst K.I., Maciuk A., Mangelsdorf I., McArdle H.J., Naska A., Pelaez C., Pentieva K., Siani A., Thies F., Tsabouri S., Vinceti M., Cubadda F., Frenzel T., Heinonen M., Maradona M.P., Marchelli R., Neuhauser-Berthold M., Poulsen M., Schlatter J.R., van Loveren H., Fernandez A., and Knutsen H.K.

Subjects
mung bean protein, novel foods, safety, Vigna radiata, ALLERGENS, 030309 nutrition & dietetics, Veterinary (miscellaneous), Novel food, Nutri1010, TP1-1185, Plant Science, DIGESTIBILITY, Biology, Microbiology, 03 medical and health sciences, 0404 agricultural biotechnology, VIGNA-RADIATA, AMINO-ACID SCORES, Medicine and Health Sciences, TX341-641, Food science, 2. Zero hunger, 0303 health sciences, Mung bean, IDENTIFICATION, Nutrition. Foods and food supply, Chemical technology, food and beverages, 04 agricultural and veterinary sciences, mung been protein, 040401 food science, LEGUMES, Scientific Opinion, SPROUTS, Animal Science and Zoology, Parasitology, Food Science
Abstract

Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on mung bean protein as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF, which is the subject of the application, is mung bean protein extracted from seeds of the plant Vigna radiata. The NF is proposed to be used as a food ingredient added to 'protein products, excluding products covered in category 1.8'. The target population is the general population. The maximum estimated intake of the NF is 758 and 260 mg/kg body weight (bw) per day in children and adults, respectively. The major constituents of this NF are protein (similar to 85%), fat (3-4%) and moisture (3-5.5%). The NF is rich in protein which is well digestible and provides sufficient amounts of most essential amino acids but only limited amounts of sulfu-rcontaining amino acids. The Panel notes that the cumulative exposure to the minerals analysed does not raise concern. The reported values for the levels of antinutritional factors in the NF are comparable to those in other foodstuffs. The Panel considers that taking into account the composition of the NF and the proposed conditions of use, consumption of the NF is not nutritionally disadvantageous. No toxicological studies with the NFs were provided by the applicant; however, the Panel considers that no toxicological studies are required on this NF. This NF has the potential capacity to sensitise individuals and to induce allergic reactions in individuals allergic to soybean, peanuts, lupin and to birch pollen. The Panel considers that the NF, i.e. mung bean protein, is safe at the proposed conditions of use. (C) 2021 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority.

Published
2021

50. Safety of pasteurised Akkermansia muciniphila as a novel food pursuant to Regulation (EU) 2015/2283

Author

EFSA Panel on Nutrition, Novel Foods, Food Allergens (NDA), Turck D., Bohn T., Castenmiller J., De Henauw S., Hirsch-Ernst K.I., Maciuk A., Mangelsdorf I., McArdle H.J., Naska A., Pelaez C., Pentieva K., Siani A., Thies F., Tsabouri S., Vinceti M., Cubadda F., Frenzel T., Heinonen M., Marchelli R., Neuhauser-Berthold M., Poulsen M., Prieto Maradona M., Schlatter J.R., van Loveren H., Ackerl R., and Knutsen H.K.

Subjects
Agriculture and Food Sciences, safety, Veterinary (miscellaneous), MUCIN, Novel food, TP1-1185, Akkermansia muciniphila, food supplement, gut microbiota, novel food, Plant Science, Gut flora, Microbiology, COLONIZATION, 03 medical and health sciences, 0302 clinical medicine, TX341-641, Food science, 030304 developmental biology, 0303 health sciences, biology, Nutrition. Foods and food supply, Chemical technology, biology.organism_classification, 3. Good health, Food supplement, BACTERIA, Animal Science and Zoology, Parasitology, 030217 neurology & neurosurgery, Food Science
Abstract

Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on pasteurised Akkermansia muciniphila as a novel food (NF) pursuant to Regulation (EU) 2015/2283. A. muciniphila is a well-characterised non-toxin producing, avirulent microorganism that has been reported as part of normal gut microbiota. The NF, pasteurised A. muciniphila, is proposed by the applicant to be used as a food supplement at max. 5 x 10(10) cells/day by adults excluding pregnant and lactating women, and in foods for special medical purposes. The Panel considers that the production process of the NF is sufficiently described and that the information provided on the composition of the NF is sufficient for its characterisation. Taking into account the composition of the NF and the proposed conditions of use, the consumption of the NF is not nutritionally disadvantageous. Based on literature data, and by applying an uncertainty factor of 200 to the no observed adverse effect level (NOAEL) of a 90-day repeated dose oral toxicity study in rats, the Panel concludes that the consumption of 3.4 x 10(10) cells/day is safe for the target population under the provision that the number of viable cells in the NF is < 10 colony forming units (CFU)/g (i.e. limit of detection). (C) 2021 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority.

Published
2021
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