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Background: Clinical outcome of patients hospitalized with COVID-19 and acute kidney injury (AKI) are not well understood. The clinical significance of abnormal electrolytes and renal outcome in COVID-19 patients have been poorly documented. We aim to exhibit the electrolyte abnormalities, renal outcome and associated risk factors in hospitalized COVID-19 patients in rural tertiary care hospital in Vadodara district, Western India. Method: A hospital record based retrospective study was conducted. Total 994 patients hospitalized with COVID-19 between 1st April 2021 to 30th June 2021 and those meeting inclusion criteria were included for the analysis. The laboratory data of interest included electrolytes reports like Na+, K+, CL-, creatinine and blood urea. Result: Of the total hospitalized COVID-19 patients, 324 patients were eligible. For the criteria for suspected AKI - 279 (86.11%) and no AKI - 45 (13.88%) patients were found. Suspected AKI patients were classified into four conditions: 1) HYPERNATREMIA (14.33%); HYPERKALEMIA (2.15%); BCR ratio >20 (65.59%); HIGH Cl- (17.92%). Out of total AKI patients, (36.91%) died whereas (13.3%) patients died in no AKI group. All patients were provided antibiotics, steroids and anti-viral therapies irrespective of AKI status, which we presume might have contributed in high mortality among suspected AKI.

Background: Patients with Diabetes Mellitus are more prone to Urinary tract infection (UTI) than non-diabetic patients. Diabetes Mellitus has certain negative effects on the genital system and increases the incidence of urinary tract infection in diabetic patients. Design: Record based retrospective study. Methods: Records of patients with type-II diabetes having symptoms of UTI were reviewed from August 2021 to January 2022. Result: Out of 210 diabetic patients, the UTI rate was higher in females 59% than male 41%. The most common agents for causing UTI were E.coli followed by Pseudomonas aeruginosa, Klebsiella spp., Candida albicans and Candida non-albicans, Enterococcus, S.aureus and other organisms. About 70.68% Gram-negative isolates were resistant against ampicillin, 75.17% resistant against gentamycin, and 48.16% resistant against amoxicillin-clavulanic acid. Gram-positive isolates were 83.33% resistant against penicillin and 83.33% resistant against ciprofloxacin. However, both gram-negative and gram-positive were susceptible to nitrofurantoin. The overall multidrug resistance was observed in 201 out of 210 (95.71%) bacterial and candiduria isolates, while 3.33% of the isolates were resistant to one only antibiotic. Conclusion: Most common etiological agent is E.coli with high drug resistance to ampicillin and susceptible to nitrofurantoin. Therefore, performing urine culture and regular monitoring of UTI is essential.

Background: This Retrospective Study was conducted by collecting patient records from the COVID-19 registry of Parul Sevasharm Hospital. The goal of this study was to investigate the risk and mortality of COVID-19 patients with Metabolic Syndrome especially during the second wave of pandemic. Methods: This Retrospective Study was conducted by collecting patient records from the COVID-19 registry of Parul Sevasharm Hospital. The record of COVID-19 patients admitted during the second wave of pandemic (April – June, 2021) were included and analyzed for Metabolic syndrome, Demographic characteristics and Clinical Outcomes. Comorbidities were classified into the following Groups: DM (having DM with or without comorbidities), only DM (having DM without other comorbidities); HT (having HT with or without other comorbidities), only HT (having HT without other comorbidities); CVD (having CVD with or without comorbidities), only CVD (having CVD without other comorbidities). Correlation analysis was also done for sub-groups of DM+CVD, CVD+HT, HT+DM, (with or without other comorbidities). Results: Among 994 Patients with COVID-19, 748/994 (75.25%) were discharged as cured and 246 (24.74%) succumbed to death. The mean age of the study population was 52.64±14.72, in which 366 (36.82%) were Females and 628/994 (63.57%) were Males.