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5 results on '"Hema E., Chart Group"'

1. A prospective survey of febrile events in hematological malignancies

Author

Pagano, L., Caira, M., Rossi, G., Tumbarello, M., Fanci, R., Garzia, M. G., Vianelli, N., Filardi, N., De Fabritiis, P., Beltrame, A., Musso, M., Piccin, A., Cuneo, A., Cattaneo, C., Aloisi, T., Riva, M., Rossi, G., Salvadori, U., Brugiatelli, M., Sannicolò, S., Morselli, M., Bonini, A., Viale, P., Nosari, A., Aversa, F., and for the Hema e-Chart Group, Italy

Published
2012
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2. A prospective survey of febrile events in hematological malignancies

Author

Pagano, L, Caira, M, Rossi, G, Tumbarello, M, Fanci, R, Garzia, Mg, Vianelli, N, Filardi, N, De Fabritiis, P, Beltrame, A, Musso, M, Piccin, A, Cuneo, Antonio, Cattaneo, C, Aloisi, T, Riva, M, Salvadori, U, Brugiatelli, M, Sannicolò, S, Morselli, M, Bonini, A, Viale, P, Nosari, A, Aversa, F, for the Hema e. Chart Group, Italy, Pagano L, Caira M, Rossi G, Tumbarello M, Fanci R, Garzia MG, Vianelli N, Filardi N, De Fabritiis P, Beltrame A, Musso M, Piccin A, Cuneo A, Cattaneo C, Aloisi T, Riva M, Salvadori U, Brugiatelli M, Sannicolò S, Morselli M, Bonini A, Viale P, Nosari A, and Aversa F

Subjects
medicine.medical_specialty, Registry, Fever, Epidemiology, Settore MED/17 - MALATTIE INFETTIVE, Hematological malignancies, Internal medicine, medicine, Humans, Prospective Studies, Prospective cohort study, Prospective survey, Febrile events, Hematology, business.industry, Coinfection, General Medicine, Bacterial Infections, medicine.disease, Settore MED/15, Surgery, Settore MED/15 - MALATTIE DEL SANGUE, Mycoses, Hematological malignancy, Virus Diseases, Hematologic Neoplasms, Cohort, HEMATOLOGICAL MALIGNANCY, business, Mixed infection
Abstract

The Hema e-Chart prospectively collected data on febrile events (FEs) in hematological malignancy patients (HMs). The aim of the study was to assess the number, causes and outcome of HM-related FEs. Data were collected in a computerized registry that systematically approached the study and the evolution of FEs developing in a cohort of adult HMs who were admitted to 19 hematology departments in Italy from March 2007 to December 2008. A total of 869 FEs in 3,197 patients with newly diagnosed HMs were recorded. Fever of unidentified origin (FUO) was observed in 386 cases (44.4%). The other causes of FE were identified as noninfectious in 48 cases (5.5%) and infectious in 435 cases (50.1%). Bacteria were the most common cause of infectious FEs (301 cases), followed by fungi (95 cases), and viruses (7 cases). Mixed agents were isolated in 32 episodes. The attributable mortality rate was 6.7% (58 FEs). No deaths were observed in viral infection or in the noninfectious groups, while 25 deaths were due to FUO, 16 to bacterial infections, 14 to fungal infections, and three to mixed infections. The Hema e-Chart provided a complete system for the epidemiological study of infectious complications in HMs.

Published
2012

3. Hema e-Chart: Italian Registry for prospective analysis of epidemiology,management and outcome of febrile events in patients with hematologicalmalignancies

Author

Pagano, L, Caira, M, Nosari, A, Rossi, G, Locatelli, F, Viale, P, Aversa, F, Collaborators: Levis A, Hema E. Chart Group I. t. a. l. y., Leoni, P, Liso, V, Baccarani, M, Cortellazzo, S, Russo, Domenico, La Nasa, G, Storti, S, Giustolisi, R, Morabito, F, Cuneo, A, Bosi, A, Capalbo, Sf, Cascavilla, N, Ghio, R, Carella, A, Brugiatelli, M, Ciceri, F, Martinelli, G, Morra, E, Pogliani, E, Mettivier, V, Carli, M, Abbadessa, V, Musso, M, Aricò, M, Lazzarino, M, Visani, G, Fioritoni, G, Di Bartolomeo, P, Vallisa, D, Petrini, M, Favre, C, Olivieri, A, Gugliotta, L, Leone, G, Amadori, S, De Rossi, G, De Fabritiis, P, Majolino, I, D'Arco, A, Lauria, F, Mazza, P, Fagioli, F, Gherlinzoni, F, Chesesi, T, and Rodeghiero, F.

Published
2010

4. A prospective survey of febrile events in hematological malignancies

Author

Pagano, Livio, Caira, Morena, Rossi, G, Tumbarello, Mario, Fanci, R, Garzia, Mg, Vianelli, N, Filardi, N, De Fabritiis, P, Beltrame, A, Musso, M, Piccin, A, Cuneo, A, Cattaneo, Chiara, Aloisi, T, Riva, M, Salvadori, U, Brugiatelli, M, Sannicolò, S, Morselli, M, Bonini, A, Viale, P, Nosari, A, Aversa, F, Hema E., Chart Group, Pagano, Livio (ORCID:0000-0001-8287-928X), Tumbarello, Mario (ORCID:0000-0002-9519-8552), Pagano, Livio, Caira, Morena, Rossi, G, Tumbarello, Mario, Fanci, R, Garzia, Mg, Vianelli, N, Filardi, N, De Fabritiis, P, Beltrame, A, Musso, M, Piccin, A, Cuneo, A, Cattaneo, Chiara, Aloisi, T, Riva, M, Salvadori, U, Brugiatelli, M, Sannicolò, S, Morselli, M, Bonini, A, Viale, P, Nosari, A, Aversa, F, Hema E., Chart Group, Pagano, Livio (ORCID:0000-0001-8287-928X), and Tumbarello, Mario (ORCID:0000-0002-9519-8552)

Abstract

The Hema e-Chart prospectively collected data on febrile events (FEs) in hematological malignancy patients (HMs). The aim of the study was to assess the number, causes and outcome of HM-related FEs. Data were collected in a computerized registry that systematically approached the study and the evolution of FEs developing in a cohort of adult HMs who were admitted to 19 hematology departments in Italy from March 2007 to December 2008. A total of 869 FEs in 3,197 patients with newly diagnosed HMs were recorded. Fever of unidentified origin (FUO) was observed in 386 cases (44.4%). The other causes of FE were identified as noninfectious in 48 cases (5.5%) and infectious in 435 cases (50.1%). Bacteria were the most common cause of infectious FEs (301 cases), followed by fungi (95 cases), and viruses (7 cases). Mixed agents were isolated in 32 episodes. The attributable mortality rate was 6.7% (58 FEs). No deaths were observed in viral infection or in the noninfectious groups, while 25 deaths were due to FUO, 16 to bacterial infections, 14 to fungal infections, and three to mixed infections. The Hema e-Chart provided a complete system for the epidemiological study of infectious complications in HMs.

Published
2012

5. Hema e-Chart: Italian Registry for prospective analysis of epidemiology, management and outcome of febrile events in patients with hematological malignancies

Author

Pagano, L, Caira, M, Nosari, A, Rossi, G, Locatelli, F, Viale, P, Aversa, F, Chart Group Italy:CollaboratorsLevis A, Hema E., Leoni, P, Liso, V, Baccarani, M, Cortellazzo, S, Russo, D, La Nasa, G, Storti, S, Giustolisi, R, Morabito, F, Cuneo, Antonio, Bosi, A, Capalbo, Sf, Cascavilla, N, Ghio, R, Carella, A, Brugiatelli, M, Ciceri, F, Martinelli, G, Morra, E, Pogliani, E, Mettivier, V, Carli, M, Abbadessa, V, Musso, M, Aricò, M, Lazzarino, M, Visani, G, Fioritoni, G, Di Bartolomeo, P, Vallisa, D, Petrini, M, Favre, C, Olivieri, A, Gugliotta, L, Leone, G, Amadori, S, De Rossi, G, De Fabritiis, P, Majolino, I, D'Arco, A, Lauria, F, Mazza, P, Fagioli, F, Gherlinzoni, F, Chesesi, T, Rodeghiero, F., Pagano L, Caira M, Nosari A, Rossi G, Locatelli F, Viale P, Aversa F, Baccarani M, and Hema E-Chart Group Italy.

Subjects
medicine.medical_specialty, Pediatrics, Myeloid, Fever, medicine.medical_treatment, Hematopoietic stem cell transplantation, hemic and lymphatic diseases, Epidemiology, medicine, Humans, Pharmacology (medical), Prospective Studies, Registries, Medical diagnosis, Prospective cohort study, Multiple myeloma, Pharmacology, HAEMATOLOGY, business.industry, Incidence, Incidence (epidemiology), Hematopoietic Stem Cell Transplantation, FUNGI, Fungal infection, Hematological malignancies, medicine.disease, Surgery, Lymphoma, Settore MED/15 - MALATTIE DEL SANGUE, Infectious Diseases, medicine.anatomical_structure, Italy, Mycoses, Oncology, Hematologic Neoplasms, business
Abstract

The aim of the study was to create a prospective computerized registry to collect and analyze febrile events, particularly due to fungal infections, in patients with hematological malignancies. A systematic approach that starts from the registration of new diagnosis and complete follow-up can be of help for the study of treatment and evolution of these complications. The software allows several concurrent users to create and manage medical information in a website. Its aim is to improve the speed, quality and integration of information related to subjects with febrile event, ultimately resulting in improving patients' care.Patients included adults and children with acute and chronic myeloid or lymphoid leukemia, Hodgkin's and non-Hodgkin's lymphoma, myelodysplastic syndrome, or multiple myeloma. The registry also included data regarding event onset in hematopoietic stem cell transplants (HSCTs). In order to evaluate the incidence of febrile events, all new diagnoses of hematological malignancy and all HSCTs were reported.The Hema e-Chart can be a very useful network collecting information about febrile events in patients with hematological malignancy and HSCTs. Significant trends and treatment practices are expected to be observed. As enrollment continues, data will be analyzed and published, which will provide valuable information concerning the epidemiology, therapy, and outcome of infectious complications.

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