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The implementation between machine learning and the Internet of Things (IoT) has been scientifically investigated in many studies. However, not many bibliometric studies categorize the output in this area. By keeping an eye on the publications posted on the Web of Science (WoS) platform, this study aims to give a bibliometric analysis of research on Machine Learning and IoT, identifying the state of the art, trends, and other indicators. 6.170 different articles made up the sample. The VOS viewer software was used to process the data and graphically display the results. The study examined the concurrent occurrence of publications by year, keyword trends, co-citations, bibliographic coupling, and analysis of co-authorship, countries, and institutions. several prolific authors are discovered. However, the body of literature on machine learning and IoT issues is expanding quickly; only five papers accounted for more than 2193 citations. Then, 40.34 percent of the articles from the 694 sources reviewed were published as the most important paper. At the same time, the USA is the top nation for research on this subject area. In addition to identifying gaps and promising areas for future research, this study offers insight into the current state of the art and the field of machine learning and IoT.

An emerging outbreak of Covid-19 has now been detected across the globe. Given this pandemic condition, the robust estimation reports are urgently needed. Therefore, this study aims to analyze the impacts of community mobility (before, during, and after the lockdown period) on the spread of the Covid-19 in Jakarta, Indonesia. The secondary data was derived from surveillance data for Covid-19 daily cases from the Health Office of DKI Jakarta Province and the Ministry of Health. The community mobility indicators were retrieved from the Google website. Our results showed that in the pre-lockdown period, the Covid-19 daily cases rapidly increased, while community mobility significantly dropped. The increasing number of Covid-19 daily cases was significantly affected by the number of Covid-19 tests per day rather than community mobility. During the restriction period, the number of Covid-19 tests per day, and community mobility statistically affected the decreasing number of Covid-19 daily cases. Meanwhile, after the lockdown period, the number of Covid-19 daily cases rapidly increased, which significantly has a direct relationship with the increasing level of community mobility. Overall, community mobility and the number of tests per day are the essential variables that explain the number of Covid-19 daily cases in Jakarta, Indonesia. Additionally, this study did not observe any impact of average air temperature and air pollution on the spread of Covid-19. This study figures out that community mobility could potentially explain the progression of Covid-19.

Moraxella catarrhalis (M. catarrhalis) is a Gram-negative bacterium that can cause serious respiratory tract infections and middle ear infections in children and adults. M. catarrhalis has demonstrated an increasing rate of antibiotic resistance in the last few years, thus development of an effective vaccine is a major health priority. We report here a novel designed multitope vaccine based on the mapped epitopes of the vaccine candidates filtered out of the whole proteome of M. catarrhalis. After analysis of 1615 proteins using a reverse vaccinology approach, only two proteins (outer membrane protein assembly factor BamA and LPS assembly protein LptD) were nominated as potential vaccine candidates. These proteins were found to be essential, outer membrane, virulent and non-human homologs with appropriate molecular weight and high antigenicity score. For each protein, cytotoxic T lymphocyte (CTL), helper T lymphocyte (HTL) and B cell lymphocyte (BCL) epitopes were predicted and confirmed to be highly antigenic and cover conserved regions of the proteins. The mapped epitopes constituted the base of the designed multitope vaccine where suitable linkers were added to conjugate them. Additionally, beta defensin adjuvant and pan-HLA DR-binding epitope (PADRE) peptide were also incorporated into the construct to improve the stimulated immune response. The constructed multitope vaccine was analyzed for its physicochemical, structural and immunological characteristics and it was found to be antigenic, soluble, stable, non-allergenic and have a high affinity to its target receptor. Although the in silico analysis of the current study revealed that the designed multitope vaccine has the ability to trigger a specific immune response against M. catarrhalis, additional translational research is required to confirm the effectiveness of the designed vaccine.

The 2.7 kilometers double track elevated viaducts of Doha metro green line, currently under construction, consist of cast-in-situ and precast segmental simply supported spans ranging from 20 to 35 m and continuous cast-insitu two and three spans (30-57 m), (50-51-44 m) and (37-68-37 m) U-trough decks. The non-typical configuration of the continuous span arrangements was imposed to the designer by existing underneath utilities and infrastructures. In order to ensure the passenger comfort and traffic safety by preventing track instability during train operation for this special landmark project, performing a dynamic analysis was vital. The dynamic analysis focuses on the vertical accelerations and vertical displacements as well as lateral frequencies of vibration. All simply supported spans as well as the continuous spans of the project are considered. The real train of the project composed of 6 vehicles with a total length of 120m and with actual axle loads (maximum axle load of 160 kN with 4 axles per vehicle) is adopted in the dynamic analysis. The analysis is carried out using both direct time integration of the equation of motion and modal time history analysis for different train speeds ranging from 60 km/hr to the maximum permissible speed along the metro line (160 km/hr) with the maximum operating speed ranging from 100 to 130 km/hr. For each train speed the maximum vertical acceleration and the maximum vertical deflection are monitored using the CSI bridge software and are compared to the allowable values given in EN 1991-2 and EN 1990-Annex 2. According to relevant Euronorm requirements, the vertical accelerations and the vertical deflections were found acceptable for all segments of the elevated viaduct.

C-reactive protein (CRP) is an inflammatory biomarker with associated clinical utility in a wide number of inflammatory disorders, including rheumatoid arthritis (RA). The interaction of CRP with pro-inflammatory cytokines has been explored before, however its role in complement regulation is more subtle, where CRP is capable of both up and downregulating the complement cascade. CRP is produced in a pentameric form and can dissociate to a monomeric form in circulation which has significant implications for its ability to interact with receptors and binding partners. This dichotomy of CRP structure could have relevance in patients with RA who have significant dysfunction in their complement cascade and also widely varying CRP levels including at the time of flare. This review aims to bring together current knowledge of CRP in its various forms, its effects on complement function and how this could influence pathology in the context of RA., (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)

Background Laser acupuncture is one of the complementary modalities used for treating osteoarthritis. The study was performed to evaluate the effectiveness of laser acupuncture in the treatment of grade 2 knee osteoarthritis. Patients and methods Forty patients having bilateral knee osteoarthritis were divided into two groups (20 patients in each group). The patients of the first group were subjected to 12 laser sessions at the following acupoints (St 35, St36, Sp9, Sp10 and Gb 34). During each session, laser of 90 mw was directed to each acupoint for 1 min giving energy of 5.4 joules. Energy of 21.6 joules was directed to ashi points. The laser had a wavelength of 808 nm, beam diameter 2 mm and was applied with a continuous wave. The cases of the second group were used as controls. Each patient is exposed to sham laser (laser probe is directed to the same acupoints while the device is off). Results The 20 patients receiving laser showed significant improvement in pain on (VAS), increase in serum beta-endorphin and a decrease in substance P more than those exposed to sham laser. Conclusions Laser acupuncture is a safe and cheap tool for management of grade 2 knee osteoarthritis.

The objectives of the present work are to determine the prevalence and risk factors of occurrence of occupational dermatoses among workers in a porcelain manufacturing factory. The study included 235 workers (132 males and 103 females). After history taking, dermatological examination was performed at the work place. Cases of contact dermatitis (CD) were patch tested using potassium dichromate 0.5%, Cobalt chloride 1% and Nickel sulphate 5% in petrolatum. Results showed that the prevalence of occupational dermatoses (OD) was 26.8% among exposed workers. The highest percentage of OD was found among workers in the decoration department. It represented 30.2% of all cases. CD was the commonest presentation among the studied group, it represented 27% of all cases of OD. Results of patch testing indicated that out of 17 cases of CD 12 cases (70%) were of the irritant variety and 5 cases (30%) were of the allergic type. The prevalence of OD was found to be affected by age, duration of work, type of exposure and daily bathing after work.