1. The minimal clinically important difference of the control of allergic rhinitis and asthma test (CARAT): cross-cultural validation and relation with pollen counts
- Author
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Ioanna Tsiligianni, Bertine M. J. Flokstra-de Blok, Thys van der Molen, Roland A. Riemersma, Letty A. de Weger, P. N. Richard Dekhuijzen, Frederik van Gemert, Sander van der Leeuw, Roy Gerth van Wijk, Joanne N.G. Oude Elberink, Helma Oosterom, Janwillem W. H. Kocks, João Fonseca, Groningen Research Institute for Asthma and COPD (GRIAC), and Internal Medicine
- Subjects
Adult ,Cross-Cultural Comparison ,Male ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Pediatrics ,Adolescent ,Visual analogue scale ,QUESTIONNAIRE ,Article ,Young Adult ,Cronbach's alpha ,Quality of life ,QUALITY-OF-LIFE ,Surveys and Questionnaires ,SCORE ,medicine ,Humans ,Aged ,Asthma ,RISK ,Carat ,HEALTH-STATUS ,Primary Health Care ,business.industry ,Minimal clinically important difference ,Public Health, Environmental and Occupational Health ,Reproducibility of Results ,Middle Aged ,medicine.disease ,Rhinitis, Allergic ,humanities ,Standard error ,Asthma Control Questionnaire ,Physical therapy ,Inflammatory diseases Radboud Institute for Health Sciences [Radboudumc 5] ,Female ,TRIAL ,business - Abstract
The Control of Allergic Rhinitis and Asthma Test (CARAT) monitors control of asthma and allergic rhinitis. To determine the CARAT’s minimal clinically important difference (MCID) and to evaluate the psychometric properties of the Dutch CARAT. CARAT was applied in three measurements at 1-month intervals. Patients diagnosed with asthma and/or rhinitis were approached. MCID was evaluated using Global Rating of Change (GRC) and standard error of measurement (s.e.m.). Cronbach’s alpha was used to evaluate internal consistency. Spearman’s correlation coefficients were calculated between CARAT, the Asthma Control Questionnaire (ACQ5) and the Visual Analog Scale (VAS) on airway symptoms to determine construct and longitudinal validity. Test–retest reliability was evaluated with intra-class correlation coefficient (ICC). Changes in pollen counts were compared with delta CARAT and ACQ5 scores. A total of 92 patients were included. The MCID of the CARAT was 3.50 based on GRC scores; the s.e.m. was 2.83. Cronbach’s alpha was 0.82. Correlation coefficients between CARAT and ACQ5 and VAS questions ranged from 0.64 to 0.76 (P
- Published
- 2015