948 results on '"Helin, Kristian"'
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2. Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization
3. Keep quiet: the HUSH complex in transcriptional silencing and disease
4. TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers
5. Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation
6. Author Correction: EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
7. H3K4me3 regulates RNA polymerase II promoter-proximal pause-release
8. The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes
9. EZH2i unlocks PDAC immune surveillance
10. Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1
11. Author Correction: H3K4me3 regulates RNA polymerase II promoter-proximal pause-release
12. The methylation inhibitor 3DZNep promotes HDR pathway choice during CRISPR-Cas9 genome editing
13. RIO-kinase 2 is essential for hematopoiesis
14. Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals
15. Catching active enhancers via H2B N-terminal acetylation
16. BMP2/SMAD pathway activation in JAK2/p53-mutant megakaryocyte/erythroid progenitors promotes leukemic transformation
17. CpG island reconfiguration for the establishment and synchronization of polycomb functions upon exit from naive pluripotency
18. Targeting RIOK2 ATPase activity leads to decreased protein synthesis and cell death in acute myeloid leukemia
19. Publisher Correction: H3K4me3 regulates RNA polymerase II promoter-proximal pause-release
20. Correction: Utx Is Required for Proper Induction of Ectoderm and Mesoderm during Differentiation of Embryonic Stem Cells.
21. An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions
22. Discovery of NSD2‐Degraders from Novel and Selective DEL Hits
23. Discovery of NSD2‐Degraders from Novel and Selective DEL Hits
24. TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis
25. MPP8 is essential for sustaining self-renewal of ground-state pluripotent stem cells
26. ChIP-Sequencing of TET Proteins
27. KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes
28. PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia
29. Corrigendum: The Polycomb group proteins bind throughout theINK4A-ARFlocus and are disassociated in senescent cells
30. Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation
31. The Histone Demethylase PHF8 Governs Retinoic Acid Response in Acute Promyelocytic Leukemia
32. HER2-positive breast-cancer cell lines are sensitive to KDM5 inhibition: definition of a gene-expression model for the selection of sensitive cases
33. Loss of Geminin Induces Rereplication in the Presence of Functional p53
34. Figures S1-S5 from The SETDB1–TRIM28 Complex Suppresses Antitumor Immunity
35. Table S1 from The SETDB1–TRIM28 Complex Suppresses Antitumor Immunity
36. Data from The SETDB1–TRIM28 Complex Suppresses Antitumor Immunity
37. Data from PRMT5 Inhibition Modulates E2F1 Methylation and Gene-Regulatory Networks Leading to Therapeutic Efficacy in JAK2V617F-Mutant MPN
38. Supplementary Data from PRMT5 Inhibition Modulates E2F1 Methylation and Gene-Regulatory Networks Leading to Therapeutic Efficacy in JAK2V617F-Mutant MPN
39. Identification of recurrent FHL2-GLI2 oncogenic fusion in sclerosing stromal tumors of the ovary
40. APAF1 Is a Key Transcriptional Target for p53 in the Regulation of Neuronal Cell Death
41. Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2
42. Loss of the Retinoblastoma Protein-Related p130 Protein in Small Cell Lung Carcinoma
43. Supplementary Table 1 from The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation
44. Supplementary Table 3 from The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation
45. Supplementary Table 2 from The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation
46. Supplementary Figure 5 from Inhibition of GSK3B Bypass Drug Resistance of p53-Null Colon Carcinomas by Enabling Necroptosis in Response to Chemotherapy
47. Supplementary Figure 4 from Inhibition of GSK3B Bypass Drug Resistance of p53-Null Colon Carcinomas by Enabling Necroptosis in Response to Chemotherapy
48. Supplementary Table 1 from Inhibition of GSK3B Bypass Drug Resistance of p53-Null Colon Carcinomas by Enabling Necroptosis in Response to Chemotherapy
49. Supplementary Data from Inhibition of GSK3B Bypass Drug Resistance of p53-Null Colon Carcinomas by Enabling Necroptosis in Response to Chemotherapy
50. Supplementary Data from The Histone Methyltransferase and Putative Oncoprotein MMSET Is Overexpressed in a Large Variety of Human Tumors
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