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IntroductionThe ABLE Exoskeleton has been tested to be safe and feasible for persons with spinal cord injury (SCI) to complete basic skills in clinical settings but has not been tested for use in home and community environments. A user-centered design process was employed to test the feasibility of the current ABLE Exoskeleton (designed for clinical use) for persons with SCI to perform the basic and advanced skills required for home and community environments, to gain crucial feedback for the development of a novel personal-use exoskeleton.MethodsIn this prospective pretest-posttest quasi-experimental study across two SCI centers (Germany, Spain), in-and outpatients with SCI were included into a 22-session training and assessment protocol, utilizing the ABLE Exoskeleton. Feasibility and usability measures [level of assistance (LoA) for basic and advanced skills, donning/doffing-time and LoA] were recorded together with safety outcomes, and participant and therapist satisfaction with the device.Results10 participants (44.4 ± 24 years), with SCI from C5 to T11, (American Spinal Injury Association Impairment Scale A–D) completed the study. In 209 sessions, six device-related adverse events (pain and skin lesions) were reported. Average total time for don and doff was 10:23 ± 3:30 min. Eight participants were able to complete don and doff with minimal assistance or less. Independence to carry out all skills in the device increased significantly for all participants (p

Resumen Este estudio forma parte del proyecto mateMad que tiene como objetivo optimizar los materiales urbanos para hacer que los barrios desfavorecidos sean más habitables y sostenibles. El objetivo de este estudio preliminar es analizar la atención visual y el compromiso humano-fachada hacia las fachadas de edificios en barrios desfavorecidos en Madrid con el fin de crear barrios hermosos, sostenibles e inclusivos. La falta de simetría a lo largo del eje vertical y un tamaño geométrico no similar de las ventanas, mantenimiento deficiente, falta de transparencia de las ventanas y homogeneidad en color y textura resultaron en una mayor angustia subjetiva reportada, mientras que la simetría horizontal/vertical y la misma forma/tamaño de ventana resultaron en menos angustia. Abstract This study is part of the mateMad project that aims to optimize urban materials to make deprived neighbourhoods more liveable and sustainable. The objective of this preliminary study is to analyse visual attention and human-façade engagement towards building façades in deprived neighbourhoods in Madrid to the end of creating beautiful, sustainable, and inclusive neighbourhoods. A lack of symmetry along the vertical axis and a-similar geometrical size of windows, poor maintenance, non-transparency of windows, and non-homogeneity in colour and texture resulted in more reported subjective distress, whereas horizontal/vertical symmetry and same window shape/size resulted in less.

Financial difficulties experienced by cancer patients negatively impact the mental health of the patients. The objective of this study was to examine the mediating role of financial difficulties between physical symptoms and depression in patients with advanced cancer. A prospective, cross-sectional design was adopted in the study. The data were collected from 861 participants with advanced cancer in 15 different tertiary hospitals in Spain. The participants’ socio-demographic characteristics were collected using a standardized self-report form. Hierarchical linear regression models were used to explore the mediating role of financial difficulties. In the results, 24% of patients reported a high level of financial difficulties. Physical symptoms were positively associated with financial difficulties and depression (β = 0.46 and β = 0.43, respectively), and financial difficulties was positively associated with depression (β = 0.26). Additionally, financial difficulties played a role in explaining the relationship between physical symptoms and depression, showing a standardized regression coefficient of 0.43 which decreased to 0.39 after the financial difficulties were controlled. Healthcare professionals should consider the importance of providing financial resources and emotional support to help patients and their families cope with the financial burden associated with cancer treatment and its symptoms.

Objective To evaluate the efficacy of dietary supplementation with a combination of antioxidants (lipoic acid, N-acetylcysteine, vitamin B6, and S-adenosyl-L-methionine) for the modulation of metabolic, endocrine, and clinical parameters in comparison with oral contraception in non-diabetic women newly diagnosed with polycystic ovary syndrome (PCOS).Methods This was a prospective, partially randomized, multicenter study in which non-diabetic women with PCOS were recruited under routine clinical practice conditions and distributed in three groups to receive the following regimen for 6 months: 1) antioxidant combination (MN group); 2) oral contraception (OC group); or 3) oral contraception and the antioxidant combination (MN + OC group). General recommendation of healthy diet and regular exercise was given to all patients. Metabolic, endocrine, clinical, and quality of life parameters were recorded at baseline and after 6 months of therapy.Results A total of 96 women with PCOS were included in the study. After 6 months of treatment, the homeostasis model assessment-estimated insulin resistance (HOMA-IR) level was reduced only in the MN group, with a significant mean reduction of −0.92 points. Androstenedione was significantly reduced in all groups. Clinical parameters that significantly improved in all groups were hirsutism, acne, irregular menstruation, and quality of life, with no statistical differences between the groups.Conclusions This study showed that the antioxidant combination might be a suitable therapy for patients with PCOS when oral contraceptive is not indicated, because in all groups clinical parameters, irregular menstruation as well as androstenedione and quality of life were significantly improved with no statistical difference between groups.

El presente trabajo pretende ser una nueva contribución y puesta al día sobre una interesante cuestión que ha intrigado a la historiografía durante siglos. Las incógnitas sobre la naturaleza del régimen instaurado por Augusto una vez se hizo con el poder en solitario han atraído la atención de los historiadores desde el siglo XIX (Mommsen, 1876-1888; Puchta, 1882; Kromayer, 1888; Pellham, 1888; Abele, 1891; Gardthausen, 1896; Bonfante, 1902; Betti, 1915; Dessau, 1924; Von Premerstein, 1937, y un largo etc.). Tradicionalmente se ha considerado que la posición imperial estaría constituida por una serie de elementos individuales que, en conjunto, darían unos grandes poderes a su poseedor, sin por ello crear una nueva institución como tal. Entre los principales poderes detentados por Augusto y sus sucesores se han señalado especialmente el imperium, el control de una serie de provincias y la tribunicia potestas. En este trabajo la atención se dirigirá hacia el primero de estos elementos, pues, dentro del amplio tema, un lugar central lo ocupa la definición de las características del imperium del primer princeps. La confusión en los acontecimientos que siguieron al 31 a. C. y las acciones y disposiciones de Augusto no ayudan a clarificar los hechos, siendo extremadamente complicado atribuir intervenciones imperiales a un poder concreto. Mi intención es exponer los acontecimientos que siguieron a la toma del poder en solitario explicando, a través de las distintas percepciones de los principales autores expertos sobre la materia, las interpretaciones dadas a la conformación del imperium de los príncipes. Aunque mi análisis sea profundamente historiográfico, ello no excluye que también se intente aportar una visión particular sobre el tema a tratar, lo que contribuirá a mantener vivo este tema centenario que está lejos de ser concluido.

La escolarización en el período extraordinario o movilidad del alumnado es uno de los procesos menos abordados desde la investigación en el ámbito educativo (Carrasco et al., 2012). Diversos autores (Aramburu, 2002; Bonal y Zancajo, 2020; Piemontese, 2018) afirman que es un proceso altamente complejo y que suele generar segregación escolar. Por ello, este estudio tiene como objetivo conocer el proceso de admisión de estudiantes en período extraordinario de un municipio del sur de Madrid desde la perspectiva de sus protagonistas. Para alcanzarlo, se ha desarrollado un estudio de caso con seis entrevistas semiestructuradas a directores escolares, representantes del AMPA y representantes de la Comunidad de Madrid y el ayuntamiento. Los resultados muestran que existe un gran descontento con el proceso de matriculación fuera del período ordinario, especialmente porque genera desequilibrio entre los centros escolares al ser las familias las que eligen el centro al que llevar a sus hijos (centros con plazas disponibles). Esta situación acrecienta las diferencias entre los centros que llenan su matrícula en período ordinario y los que reciben estudiantes a lo largo del curso escolar, promoviendo la desigualdad escolar y con ello, incrementando la inequidad educativa.

The quality of teacher education plays a key role in equipping students with the skills they need and it is important in avoiding learning inequalities. To bridge the digital divide and ensure that all students have equal access to technology and digital resources as well as advanced teaching–learning processes using digital tools, it is crucial to analyse the current state of teacher education in order to identify the key issues. The sample in this research consisted of 325 master of education students and in-service teachers studying at various universities (in Spain, Cyprus, and México) in the 2022–2023 academic year who filled out a questionnaire partly based on DigComEdu and this was expanded with questions relating to other digital and educational aspects. The findings reveal that there is potential for enhancement in many areas. Despite teachers having technical training associated with their profession, they lack the necessary training to overcome inequalities or digital gaps. Moreover, it is striking that those who are already working as teachers are the most pessimistic about aspects such as the use of digital resources, perhaps because of the difficulties they face in their daily work.

Abstract Introduction Most cancers occur in older individuals, who are more vulnerable due to functional impairment, multiple comorbidities, cognitive impairment, and lack of socio-familial support. These can undermine patients’ sense of dignity. This study seeks to compare dignity scores in older patients with advanced cancer on sociodemographic and clinical variables and analyze the predictive value of anxiety, depression, functional limitations, and social support on dignity scores. Methods A prospective, multicenter, observational study conducted with participation of 15 hospitals in Spain from February 2020 to October 2021. Patients with newly-diagnosed, advanced cancer completed the dignity (PPDS), anxiety and depression (BSI), Social Support (Duke–UNC-11), and functional limitations (EORTC-C30) scales. Lineal regression analyses explored the effects of anxiety, depression, functional status, and social support on dignity, adjusting for sociodemographic and clinical variables. Results A total of 180 subjects participated in this study. The results of the correlation analysis revealed that dignity correlated negatively with anxiety, depression, and sex, and positively with social support, functional status, and longer estimated survival. Thus, women, and more anxious and depressed individuals scored lower on the dignity scale, whereas patients with more social support, fewer functional limitations, and longer estimated survival scored higher. Conclusion In conclusion, being female, having a lower educational level, lower estimated survival, depression, anxiety, less social support, and limited functionality are correlated with less dignity in the elderly with advanced cancer. It is a priority to manage both physical and psychological symptoms in patients with unresectable advanced cancer to mitigate psychological distress and increase their sense of dignity.

El presente artículo pretende ofrecer una visión sobre el papel institucional desarrollado por las principales mujeres de la familia de Augusto. De esta forma nos proponemos entender la forma en que el “cargo” de emperatriz romana se comienza a perfilar a inicios del Imperio. Para ello se tiene en cuenta la labor precursora de muchas mujeres tanto de la legendaria monarquía como de la República que, con sus acciones audaces captaron la atención de los historiadores antiguos y comenzaron la senda de empoderamiento femenino, reconociéndose su relevancia en ciertos aspectos de la vida pública y política. Estas mujeres ocupan los relatos de los autores en momentos puntuales, como Tanaquil o Lucrecia en época monárquica o Cornelia, Hortensia o Fulvia en la República. Sin embargo, las mujeres de las familias imperiales y, concretamente, las de la domus Augusta, son las primeras en desarrollar un rol público constante y sistemático. Junto a la mayor parte de emperadores se encuentran mujeres poderosas que los acompañan. Así pues, en las primeras décadas del principado se da la entrada de la mujer en el ámbito del poder de una forma más abierta, reconociéndose su propia relevancia. En este sentido, en el artículo se analiza cómo, pese a la naturaleza conservadora del nuevo régimen de Augusto, se permitió este avance en la posición pública femenina sin que ello supusiese una inversión en los roles de género o un revuelo para la sociedad del momento. A través de las figuras de Octavia, Livia y Julia se estudiará la forma en que se comenzó a perfilar la posición de la mujer en el poder a través de su labor institucional como parte de la familia imperial. Así pues, estas mujeres empezarán a tener un papel propio en un terreno antes vedado. La transición culminará con las condiciones especificadas en el testamento del princeps en relación a la situación que su viuda debía mantener tras su muerte. Con ello, se consolidarán las bases del rol de emperatriz y Augusta para las restantes generaciones del Alto Imperio.

The COVID-19 pandemic has meant that home respiratory services have needed to be reviewed. As a result, new solutions have been developed and implemented. The Vivo 45™ (Breas, Mölnlycke, Sweden) is a ventilator that offers clinicians the ability to attach effort belts to the device. This allows the clinician to review ventilator traces with the addition of thoracic and abdominal activity. This allows more flexibility for the monitoring of patients at home and in the hospital, with detection of patient ventilator asynchrony (PVA). Decreasing PVA may improve ventilator adherence and increased ventilator usage improves survival. We report three cases of patients undergoing overnight monitoring with the Vivo 45™, highlighting the benefit of ventilator integrated polygraphy. In our three cases we demonstrate a simple safe tool to optimize NIV treatment over one or two-night recordings using ventilator downloaded software with the addition of effort belts and pulse oximetry without involving more than one machine and without hospitalization in a sleep unit.

Background Interatrial block (IAB) has been associated with supraventricular arrhythmias and stroke, and even with sudden cardiac death in the general population. Whether IAB is associated with life‐threatening arrhythmias (LTA) and sudden cardiac death in dilated cardiomyopathy (DCM) remains unknown. This study aimed to determine the association between IAB and LTA in ambulant patients with DCM. Methods and Results A derivation cohort (Maastricht Dilated Cardiomyopathy Registry; N=469) and an external validation cohort (Utrecht Cardiomyopathy Cohort; N=321) were used for this study. The presence of IAB (P‐wave duration>120 milliseconds) or atrial fibrillation (AF) was determined using digital calipers by physicians blinded to the study data. In the derivation cohort, IAB and AF were present in 291 (62%) and 70 (15%) patients with DCM, respectively. LTA (defined as sudden cardiac death, justified shock from implantable cardioverter‐defibrillator or anti‐tachypacing, or hemodynamic unstable ventricular fibrillation/tachycardia) occurred in 49 patients (3 with no IAB, 35 with IAB, and 11 patients with AF, respectively; median follow‐up, 4.4 years [2.1; 7.4]). The LTA‐free survival distribution significantly differed between IAB or AF versus no IAB (both P

En este artículo propongo un examen de la relación entre emociones y representaciones culturales de la intersexualidad. Me centraré tanto en El libro intersexual de la artista mexicana Adiós al futuro, al que dedicaré especial atención, como en otros materiales culturales -dos películas, un discurso escrito y un poema- para activar una lectura de los cuerpos intersexuales comprometida con la atención a las energías emocionales que están en juego. A partir de esta premisa, la principal pregunta que guía este artículo podría formularse como sigue: ¿Qué podemos saber de la representación de los cuerpos intersexuales si nos enfocamos no tanto en sus estrategias estilísticas de formalización sino en sus estrategias emocionales?

Estudiamos las semejanzas y las diferencias de dos categorías que expresan número en español: la categoría gramatical de número y la categoría léxica de numeral cardinal. Aplicamos un modelo comparativo basado en Bosque 1989. El sistema de número gramatical y el sistema de número léxico comparten la función aditiva mínima que los genera. Difieren en (a) la naturaleza de las unidades que construyen sus sistemas: unidad natural en los nombres; card(n) unidad axiomática en los números y (b) las propiedades del dominio: Semirretícula de uniones (conjunto parcialmente ordenado); secuencia de números naturales ⟨1,2,...,n⟩ ∈ ℕ (conjunto totalmente ordenado). Proponemos un modelo que generaliza los Axiomas de Peano para las funciones que construyen el sistema.

Objectives: Serum levels of potassium (K+) appear to be significantly lower in severe cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the clinical significance of this is unknown. The objective was to investigate whether hypokalemia acts as a biomarker of severity in coronavirus disease 2019 (COVID-19) pneumonia and is associated with major clinical outcomes. Methods: A retrospective cohort study of inpatients with COVID-19 pneumonia (March 3 to May 2, 2020) was performed. Patients were categorized according to nadir levels of K+ in the first 72 h of admission: hypokalemia (K+ ≤3.5 mmol/l) and normokalemia (K+ >3.5 mmol/l). The main outcomes were all-cause mortality and the need for invasive mechanical ventilation (IMV); these were analyzed by multiple logistic regression (odds ratio (OR), 95% confidence interval (CI)). Results: Three hundred and six patients were enrolled. Ninety-four patients (30.7%) had hypokalemia and these patients showed significantly higher comorbidity (Charlson comorbidity index ≥3, 30.0% vs 16.3%; p = 0.02) and CURB65 scores (median (interquartile range): 1.5 (0.0–3.0) vs 1.0 (0.0–2.0); p = 0.04), as well as higher levels of some inflammatory parameters at baseline. After adjustment for confounders, hypokalemia was independently associated with requiring IMV during the admission (OR 8.98, 95% CI 2.54–31.74). Mortality was 15.0% (n = 46) and was not influenced by low K+. Hypokalemia was associated with longer hospital and ICU stays. Conclusions: Hypokalemia is prevalent in patients with COVID-19 pneumonia. Hypokalemia is an independent predictor of IMV requirement and seems to be a sensitive biomarker of severe progression of COVID-19.

ObjectiveLoss of dignity is one of the main reasons for wishing for an early death in patients with incurable diseases such as cancer and is strongly associated with psychological distress and loss of quality of life. The present study aims to analyze the perceived dignity of patients with advanced cancer undergoing systemic treatment and their relationship with sociodemographic, clinical, and psychological factors.MethodsA prospective, cross-sectional, multicenter study was conducted in 15 oncology departments in Spain. Patients with locally advanced, unresectable, or metastatic cancer who were candidates for systemic treatment were included. Participants completed demographic information and Palliative Patients’ Dignity Scale, Brief Symptom Inventory, Mental Adjustment to Cancer, Functional Social Support Questionnaire, and Illness Uncertainty.ResultsA total of 508 patients were recruited between February 2020 and October 2021. Most were male, aged > 65 years, with digestive tumors (41%), and metastatic disease at diagnosis. Subjects were classified as having low (56%, N = 283) or high (44%, N = 225) perceived dignity. Patients ≥ 65 years, with worse baseline status (ECOG ≥ 1), and worse estimated 18-month survival had lower levels of perceived dignity. People with lower perceived dignity scored higher for anxious preoccupation and hopelessness and lower for positive attitude. They also displayed higher levels of anxiety, depression, and somatic symptoms, greater uncertainty, and less social support.ConclusionSelf-perceived dignity in advancer cancer patients is significantly associated with psychological factors, psychological distress, uncertainty, less social support. Knowledge of these specific interactions is importance for adequate, comprehensive palliative care.

Escuché, y ahora leo con enorme placer, el texto de Pedro Paulo, por su riqueza imaginativa en torno a “la posibilidad de lo imposible” contenida en la teoría y la acción queer, por la provocación que él mismo reconoce y, también, porque su elaboración conceptual, ciertamente hermosa, me consta que está basada en un importantísimo trabajo como antropólogo del cuerpo. He estructurado mi comentario alrededor de tres preguntas. En las dos primeras me detendré brevemente, y la tercera la formulo como un interrogante abierto.

Este artículo pretende examinar cómo un feminismo decolonial, situado en Latinoamérica, puede movilizar una crítica muy potente al capitalismo heteronormativo global. Además, y con atención a ejemplos de la práctica docente en México, se propone una consideración de esta crítica desde el punto de vista de su pedagogía en la educación superior. Con este fin consideramos las nociones teóricas de experiencia y memoria.

Antecedentes/Objetivo: La inteligencia emocional es una variable que ha sido objeto de un incremento notable de investigación a lo largo de los últimos años. La inteligencia emocional ha mostrado numerosas relaciones con múltiples variables psicológicas, destacando su conexión con diversos trastornos físicos y psicológicos. El objetivo del presente estudio es analizar los efectos directos e indirectos que la inteligencia emocional ejerce sobre la manifestación de sintomatología somática y psicológica, así como sobre el desarrollo de trastornos como el síndrome de burnout en un grupo de profesionales cuya labor social resulta esencial. Método: Se aplicaron las escalas Trait Meta-Mood Scale-24, Maslach Burnout Inventory-22 y General Health Questionnaire-28 a un total de 881 sacerdotes católicos latinoamericanos (M edad=45,89; DT edad=11,58). Resultados: Mediante path analysis se muestra el efecto que la inteligencia emocional, especialmente la atención y claridad emocional, ejerce sobre las alteraciones somáticas y psicológicas. Conclusiones: Tanto los trastornos específicos como el bienestar general presentan una relación clara con la inteligencia emocional. Proporcionar programas formativos efectivos que desarrollen la inteligencia emocional podría reducir la aparición de trastornos físicos y emocionales. © 2017 Asociación Española de Psicología Conductual. Published by Elsevier España, S.L.U. This is an open access article under the CC BY−NC−ND license (http://creativecommons. org/licenses/by−nc−nd/4.0/).

En este artículo pretendo analizar dos cuestiones en relación con las memorias de guerra de la militante anarquista Sara Berenguer. En primer lugar, quiero atender a las estrategias discursivas (clase, género, sexualidad) de construcción de la subjetividad en este texto. Además, me interesa indagar cómo estos discursos se interseccionan con la posición espacio-temporal (tiempo de la memoria y tiempo-espacio del exilio) del sujeto autobiográfico. Mi objetivo principal es proponer una problematización de los conceptos de “memoria colectiva” y de “experiencia femenina” y reivindicar, por lo tanto, la relevancia tanto teórica como política de análisis críticos basados en narrativas personales.

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Abstract Aims In low‐risk patients with severe aortic stenosis (AS), sutureless surgical aortic valve replacement (SU‐SAVR) may be an alternative to transcatheter aortic valve implantation (TAVI). The risk of heart failure hospitalization (HFH) after aortic valve replacement (AVR) in this population is incompletely characterized. This study aims to investigate the incidence, predictors, and outcomes of HFH in patients undergoing SU‐SAVR versus TAVI. Methods and results Patients referred for AVR between 2013 and 2020 at two centres were consecutively included. The decision for SU‐SAVR or TAVI was determined by a multidisciplinary Heart Team. Cox regression and competing risk analysis were conducted to assess adverse events. Of 594 patients (mean age 77.5 ± 6.4, 59.8% male), 424 underwent SU‐SAVR, while 170 underwent TAVI. Following a mean follow‐up of 34.1 ± 23.1 months, HFH occurred in 112 (27.8%) SU‐SAVR patients and in 8 (4.8%) TAVI patients (P

Copyright of Human Review is the property of Eagora Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)