39 results on '"Helen Mackie"'
Search Results
2. A new indocyanine green fluorescence lymphography protocol for identification of the lymphatic drainage pathway for patients with breast cancer-related lymphoedema
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Hiroo Suami, Asha Heydon-White, Helen Mackie, Sharon Czerniec, Louise Koelmeyer, and John Boyages
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Lymphoedema ,Lymphography ,Lymphatic system ,Manual lymphatic drainage ,Breast cancer ,Molecular imaging ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Breast cancer related lymphoedema (BCRL) is a common side effect of cancer treatment. Recently indocyanine green (ICG) fluorescent lymphography has become a popular method for imaging the lymphatics, however there are no standard protocols nor imaging criteria. We have developed a prospective protocol to aid in the diagnosis and therapeutic management of BCRL. Methods Lymphatic imaging procedures were conducted in three phases. Following initial observation of spontaneous movement of ICG in phase one, manual lymphatic drainage (MLD) massage was applied to facilitate ICG transit via the lymphatics in phase two. All imaging data was collected in phase three. Continuous lymphatic imaging of the upper limb was conducted for approximately an hour and lymphatic drainage pathways were determined. Correlations between the drainage pathway and MD Anderson Cancer Centre (MDACC) ICG lymphoedema stage were investigated. Results One hundred and three upper limbs with BCRL were assessed with this new protocol. Despite most of the patients having undergone axillary node dissection, the ipsilateral axilla drainage pathway was the most common (67% of upper limbs). We found drainage to the ipsilateral axilla decreased as MDACC stage increased. Our results suggest that the axillary pathway remained patent for over two-thirds of patients, rather than completely obstructed as conventionally thought to be the case for BCRL. Conclusions We developed a new ICG lymphography protocol for diagnosing BCRL focusing on identification of an individual patient’s lymphatic drainage pathway after lymph node surgery. The new ICG lymphography protocol will allow a personalised approach to manual lymphatic drainage massage and potentially surgery.
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- 2019
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3. Lipidomic Profiling of Adipose Tissue Reveals an Inflammatory Signature in Cancer-Related and Primary Lymphedema.
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Lisa M Sedger, Dedreia L Tull, Malcolm J McConville, David P De Souza, Thusitha W T Rupasinghe, Spencer J Williams, Saravanan Dayalan, Daniel Lanzer, Helen Mackie, Thomas C Lam, and John Boyages
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Medicine ,Science - Abstract
Cancer-related and primary lymphedema (LE) are associated with the production of adipose tissue (AT). Nothing is known, however, about the lipid-based molecules that comprise LE AT. We therefore analyzed lipid molecules in lipoaspirates and serum obtained from LE patients, and compared them to lipoaspirates from cosmetic surgery patients and healthy control cohort serum. LE patient serum analysis demonstrated that triglycerides, HDL- and LDL-cholesterol and lipid transport molecules remained within the normal range, with no alterations in individual fatty acids. The lipidomic analysis also identified 275 lipid-based molecules, including triacylglycerides, diacylglycerides, fatty acids and phospholipids in AT oil and fat. Although the majority of lipid molecules were present in a similar abundance in LE and non-LE samples, there were several small changes: increased C20:5-containing triacylglycerides, reduced C10:0 caprinic and C24:1 nervonic acids. LE AT oil also contained a signature of increased cyclopropane-type fatty acids and inflammatory mediators arachidonic acid and ceramides. Interestingly C20:5 and C22:6 omega-3-type lipids are increased in LE AT, correlating with LE years. Hence, LE AT has a normal lipid profile containing a signature of inflammation and omega-3-lipids. It remains unclear, however, whether these differences reflect a small-scale global metabolic disturbance or effects within localised inflammatory foci.
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- 2016
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4. A new indocyanine green fluorescence lymphography protocol for diagnostic assessment of lower limb lymphoedema
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Hiroo Suami, Belinda Thompson, Helen Mackie, Robbie Blackwell, Asha Heydon-White, Fiona Tisdall Blake, John Boyages, and Louise Koelmeyer
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Indocyanine Green ,Lower Extremity ,Humans ,Lymphography ,Surgery ,Prospective Studies ,Lymphedema ,Lymphatic Vessels - Abstract
The lower limbs are a common body site affected by chronic edema. Imaging examination of the lymphatic system is useful to diagnose lymphoedema, identify structural changes in individuals, and guide interventional strategies. In this study, we used a protocol combining indocyanine green (ICG) lymphography and ICG-guided manual lymphatic drainage (MLD) for the diagnostic assessment of lower limb lymphoedema.Patients with lower limb lymphoedema were divided into three groups by their medical history: primary, secondary cancer-related, or secondary non-cancer-related. ICG lymphography was conducted in three phases: initial observation, MLD to accelerate ICG dye transit and reduce imaging time, and imaging data collection. Lymphatic drainage regions were recorded, and the MD Anderson Cancer Center ICG staging was applied. We collected routine lymphoedema assessment data, including limb volume and bioimpedance spectroscopy measurements.Three hundred and twenty-six lower limbs that underwent ICG lymphography were analyzed. Eight drainage regions were identified. The ipsilateral inguinal and popliteal were recognized as the original regions, and the remaining six regions were considered compensatory regions that occur only in lymphoedema. More than half of the secondary cancer-related lower limb lymphoedema (57.6%) continued to drain to the ipsilateral inguinal region. The incidence of drainage to the ipsilateral inguinal region was even higher for the primary (82.8%) and secondary non-cancer-related (87.1%) groups. Significant associations were observed between cancer-related lymphoedema and the presence of compensatory drainage regions.We proposed a prospective ICG lymphography protocol for the diagnostic assessment of lower limb lymphoedema in combination with MLD. Eight drainage regions were identified, including two original and six compensatory regions.
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- 2022
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5. Clinical Characteristics and Implications of Indocyanine Green Lymphography-Identified Contralateral Inguinal Pathway of Lower-Limb Lymphedema
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Helen Mackie, Belinda M. Thompson, Louise A. Koelmeyer, Robbie Blackwell, Katrina Gaitatzis, Asha Heydon-White, John Boyages, and Hiroo Suami
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Oncology ,Oncology (nursing) ,Rehabilitation ,Physical Therapy, Sports Therapy and Rehabilitation - Published
- 2022
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6. Usability evaluation of a novel compact pneumatic compression device for the treatment of lymphoedema: Pilot study
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Martin Devitt, Dinesh Ramanan, Jeff Armitstead, Xueling Zhu, and Helen Mackie
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Adult ,Male ,Treatment Outcome ,Adolescent ,Edema ,Humans ,Female ,Pilot Projects ,Lymphedema ,General Medicine ,Middle Aged ,Cardiology and Cardiovascular Medicine ,Intermittent Pneumatic Compression Devices - Abstract
Objective To perform a preliminary usability evaluation of a novel, compact pneumatic compression device in patients with lymphoedema. Methods This open-label, single-arm trial had two phases: the first focused on the fitting of the pneumatic compression device (Aria FreeTM, Aria Health, San Diego CA, USA) and the second focused on evaluating the comfort of the entire system during a 45-min usage period. Both phases were conducted in a monitored clinical environment. Patients aged ≥18 years with a diagnosis of lower limb lymphoedema who had used a pneumatic compression device for ≥3 months were eligible. Patients rated subjective fit, comfort and usability on an 11-point Likert scale (where higher scores indicate better fit/comfort/usability). The truncated cone method was used to infer limb volume before and after therapy in phase 2. Results Twenty-four patients were screened, and 15 were enrolled (80% female; mean age 62 years); all completed both study phases. Patients rated the garment as easy to set up and fit (median score 6.5), and all reported that the therapy was comfortable (median score 10; p < 0.001 vs. reference score of 6). There was a 1.85% reduction in limb volume after device use for 45 min ( p = 0.018 vs. before therapy). No safety issues were identified. Conclusions The new pneumatic compression device fitted well, was easy to use and reduced leg oedema.
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- 2022
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7. The Prevalence of the Axillo-Inguinal Lymphatic Pathway in Lymphedema of the Extremities and Potential Therapeutic Implications
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Helen Mackie, Belinda Thompson, Asha Heydon-White, Hiroo Suami, Robbie Blackwell, and Louise Koelmeyer
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Cardiology and Cardiovascular Medicine - Published
- 2023
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8. Differentiation of lipoedema from bilateral lower limb lymphoedema by imaging assessment of indocyanine green lymphography
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Helen Mackie, Belinda M. Thompson, Hiroo Suami, Asha Heydon‐White, Robbie Blackwell, Fiona Tisdall Blake, and Louise A. Koelmeyer
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Endocrinology, Diabetes and Metabolism - Published
- 2023
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9. Reply
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Helen Mackie and Hiroo Suami
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Surgery ,Cardiology and Cardiovascular Medicine - Published
- 2023
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10. Staged approach to massive primary pubic and scrotal lymphangiomata
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Michael Y. Cheung, Helen Mackie, Quan Ngo, and Thomas C. Lam
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Surgery ,General Medicine - Published
- 2023
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11. TU6.6 The value of immersive endoscopy training for the surgical trainee
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Eleanor Massie, Rebecca Hughes, Mark Vella, Susan Moug, Helen Mackie, and Andrew Renwick
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Surgery - Abstract
Aims Achieving endoscopic targets for CCT is problematic for General Surgery trainees. COVID-19 has negatively impacted all aspects of surgical training. Nationally, only 19% of colorectal trainees report completing 300 colonoscopies by CCT. We report on an immersive endoscopy training programme to achieve CCT targets. Methods To confirm reduced access to endoscopy, local General Surgery trainees (n=95) were invited to complete our survey assessing their endoscopic experience during their training to date. We compared the results to outcomes from a new 6-month immersive endoscopy programme. 2 out-of-programme (OOP) trainees; one had no endoscopy experience (completed core training; OOP 1); one had attempted 70 colonoscopies and 130 UGI endoscopies (ST4; OOP2). Results 42 trainees completed the survey (44% response rate), ranging from ST2-ST8 (74% ST2-ST6, 14% ST7/ST8, 12% OOP). UGI endoscopies attempted by all trainees: mean 119 (range 10–306). 55% had attended or secured a place on the JAG UGI endoscopy course. Colonoscopies attempted by all trainees: mean 67 (range 2–233). 45% having attended or secured a place on the JAG colonoscopy course. 29% of trainees anticipated not reaching target CCT endoscopy numbers. In comparison, in 6 months; OOP1 attempted 49 OGD, 199 colonoscopies with a place secured on colonoscopy course. OOP2 attempted 109 OGD and 216 colonoscopies with both courses completed. Conclusion Shortcomings in endoscopic training and courses, particularly for colonoscopy, have been confirmed. Implementation of immersion endoscopy training can achieve CCT target numbers and competency within a short time, irrespective of previous experience.
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- 2022
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12. A 'Relephant' History
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Yu-Fang Wu, Jack Wall, Divya Namboodiri, Veronica Preda, Helen Mackie, Bernard Champion, and Hiroo Suami
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medicine.medical_specialty ,business.industry ,Family medicine ,medicine ,General Medicine ,business - Published
- 2020
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13. Retrograde lymph flow in the lymphatic vessels in limb lymphedema
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Helen Mackie, Hiroo Suami, Belinda M. Thompson, Quan Ngo, Asha Heydon-White, Robbie Blackwell, and Louise A. Koelmeyer
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Indocyanine Green ,Neoplasms ,Lymphangitis ,Humans ,Lymphography ,Surgery ,Lymphedema ,Cardiology and Cardiovascular Medicine ,Lymphatic Vessels - Abstract
Retrograde movement of lymph owing to damaged and/or incompetent valves in the lymphatic vessels has been considered a pathological feature of lymphedema. This study aimed to determine the prevalence of retrograde lymph flow and the characteristics of patients with this condition using indocyanine green (ICG) lymphography.An audit of 679 patients with upper or lower limb swelling who underwent ICG lymphography was undertaken over a 4-year period. Harvey's technique was applied to identify retrograde flow in the lymph collecting vessel during ICG lymphography. The characteristics of patients with retrograde lymph flow were recorded.Twenty-one patients (3.7%; lower limb, n = 19; upper limb, n = 2) were identified as having retrograde flow in lymph collecting vessels out of 566 confirmed lymphedema patients (lower limb, n = 275; upper limb, n = 291). Of the two patients with upper limb lymphedema (ULLE), one had a short segment of retrograde lymph flow in the forearm. The other patient with ULLE and one patient with lower limb lymphedema (LLLE) were previously diagnosed with lymphedema-distichiasis syndrome. Of the remaining 18 patients with LLLE and retrograde lymph flow, nine had initiating insect bites with lymphangitis and three had palpable benign enlarged inguinal lymph nodes evident before lower limb swelling onset. None had cancer-related LLLE.Retrograde lymph flow with valve incompetence in the lymph-collecting vessels was a rare finding in ULLE and a relatively uncommon finding in LLLE, contradicting the conventional understanding of pathological changes in lymphedema. ICG lymphography identified anticipated retrograde lymph flow in two patients with lymphedema distichiasis. In the remaining patients, retrograde lymph flow may have resulted from toxic or asymptomatic lymphangitis but there was no association with secondary cancer-related lymphedema. These findings have implication for conservative management as well as lymphovenous anastomosis surgery where both ends of a transected lymph collecting vessel would be potential targets for anastomoses.
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- 2022
14. Leadership development in undergraduate medical education: evaluation of students’ perceptions of a student-selected leadership module
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Fiona Tsim, Mohammad Abul, Ann Ln Chapman, Ross Christie, Marta Lewandowska, Helen Mackie, Ross Lamont, and Luan Tong
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Medical education ,020205 medical informatics ,Leadership development ,Leadership and Management ,business.industry ,Strategy and Management ,Health Policy ,media_common.quotation_subject ,02 engineering and technology ,Core curriculum ,Personal development ,03 medical and health sciences ,0302 clinical medicine ,Perception ,Health care ,Respondent ,0202 electrical engineering, electronic engineering, information engineering ,Medical training ,030212 general & internal medicine ,business ,Psychology ,Curriculum ,media_common - Abstract
BackgroundThere is increasing recognition of the importance of leadership development within undergraduate medical training. One method of doing this is through student-selected components (SSCs), optional modules that allow students to explore an area in greater depth than in the core curriculum. An SSC in medical leadership has been offered at the University of Glasgow since 2015. We evaluated students’ perceptions of this SSC.MethodsStudents are required to submit a written reflective report on the SSC. These were analysed thematically to determine students’ lived experience. Respondent validation and independent anonymised feedback to the university were used for triangulation.ResultsStudents reported that the SSC allowed them to experience aspects of healthcare not encountered elsewhere in their training. Three themes were derived from the analysis, relating to SSC structure, areas of learning and personal development/impact. Students recognised that leadership development is important within the curriculum and felt that it should be available to all medical students.ConclusionThis evaluation of students’ perceptions of a leadership SSC identified characteristics of the module that were felt by students to be valuable in leadership development and will support development of similar leadership modules at undergraduate and postgraduate levels.
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- 2020
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15. The ALERT model of care for the assessment and personalized management of patients with lymphoedema
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Hiroo Suami, Kevin Ho-Shon, John Boyages, Quan Ngo, Sharon Czerniec, Asha Heydon-White, Sonali Munot, Louise Koelmeyer, Helen Mackie, and Thomas Lam
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Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,MEDLINE ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Manual lymphatic drainage ,medicine ,Humans ,Lymphedema ,030212 general & internal medicine ,Disease management (health) ,Lymphatic Vessels ,Retrospective Studies ,Massage ,business.industry ,General surgery ,Anastomosis, Surgical ,Disease Management ,Lymphography ,Retrospective cohort study ,Middle Aged ,medicine.disease ,chemistry ,030220 oncology & carcinogenesis ,Liposuction ,Female ,Surgery ,business ,Vascular Surgical Procedures ,Indocyanine green - Abstract
This study documents the development and evaluation of a comprehensive multidisciplinary model for the assessment and personalized care of patients with lymphoedema.The Australian Lymphoedema Education Research and Treatment (ALERT) programme originated as an advanced clinic for patients considering surgery for lymphoedema. The programme commenced liposuction surgery in May 2012 and then introduced lymph node transfer in 2013 and lymphovenous anastomosis (LVA) in 2016. An outpatient conservative treatment clinic was established in 2016. ALERT commenced investigations with indocyanine green (ICG) lymphography in late 2015, leading to the creation of a diagnostic assessment clinic offering ICG in 2017.Since 2012, 1200 new patients have been referred to ALERT for assessment of lymphoedema for a total of 5043 episodes of care. The introduction of ICG lymphography in 2015 initially allowed better screening for LVA, but is now used not only to guide surgical options, but also as a diagnostic tool and to guide manual lymphatic drainage massage. The total number of new patients who attended the surgical assessment clinic to December 2018 was 477, with 162 patients (34·0 per cent) undergoing surgery.The ALERT programme has developed a multidisciplinary model of care for personalized lymphoedema treatment options based on clinical, imaging and ICG lymphography. Patients are selected for surgery based on several individual factors.Este estudio presenta el desarrollo y valoración de un modelo multidisciplinario integral para la evaluación y atención personalizada de pacientes con linfedema. MÉTODOS: El programa australiano de educación en investigación y tratamiento del linfedema (Australian Lymphoedema Education Research and Treatment, ALERT) se originó como un centro clínico avanzado para pacientes que consideran la cirugía como tratamiento para el linfedema. El programa se inició en mayo del 2012 con la cirugía de liposucción, introduciendo la cirugía de transferencia ganglionar (lymph node transfer, LNT) en 2013 y la anastomosis linfovenosa (lymphovenous anastomosis, LVA) en 2016. En 2016 se estableció una clínica de tratamiento conservador ambulatorio. ALERT comenzó las investigaciones con la linfografía con verde de indocianina (indocyanine green, ICG) a fines del 2015, lo que se siguió de la creación de una clínica de evaluación diagnóstica que ofrece ICG en 2017.Desde el 2012, 1.200 pacientes nuevos han sido referidos a ALERT para la evaluación de un linfedema, con un total de 5.043 episodios atendidos. La introducción inicialmente de linfografía con ICG en 2015 permitió un mejor cribaje para LVA, pero actualmente se utiliza no solo como guía de las opciones quirúrgicas, sino también como herramienta diagnóstica y como guía del masaje de drenaje linfático manual (manual lymphatic drainage, MLD). El número total de pacientes nuevos atendidos en la clínica de evaluación quirúrgica hasta diciembre de 2018 fue de 477, con 122 pacientes (34%) tratados quirúrgicamente. El modelo tal como se ha descrito, ha atraído a pacientes de toda Australia y Nueva Zelanda. CONCLUSIÓN: El programa ALERT ha desarrollado un modelo multidisciplinario de atención para las opciones de tratamiento personalizado del linfedema basado en la evaluación clínica, por imagen (MRI y LSG) y linfografía con ICG. Los pacientes se seleccionan cuidadosamente para el tratamiento quirúrgico en función de varios factores relacionados con el paciente, el tumor, los linfáticos y las opciones terapéuticas, y se someten a una evaluación detallada después de cualquier procedimiento.
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- 2019
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16. Liposuction for congenital analbuminaemia
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Oliver Chow, Thomas Lam, and Helen Mackie
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medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,General surgery ,MEDLINE ,General Medicine ,Congenital analbuminaemia ,Lipectomy ,Liposuction ,medicine ,Humans ,Surgery ,business ,Serum Albumin - Published
- 2021
17. Personalizing Conservative Lymphedema Management Using Indocyanine Green-Guided Manual Lymphatic Drainage
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Katrina Gaitatzis, B. Thompson, Hiroo Suami, Asha Heydon-White, John Boyages, Emma Moloney, Louise Koelmeyer, Helen Mackie, and Robbie Blackwell
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Adult ,Indocyanine Green ,medicine.medical_specialty ,Adolescent ,030204 cardiovascular system & hematology ,03 medical and health sciences ,chemistry.chemical_compound ,Young Adult ,0302 clinical medicine ,Manual lymphatic drainage ,Medicine ,Humans ,Lymphedema ,Aged ,Lymphatic Vessels ,Retrospective Studies ,Aged, 80 and over ,business.industry ,Australia ,Lymphography ,Middle Aged ,medicine.disease ,Effleurage ,Surgery ,body regions ,Axilla ,Lymphatic system ,medicine.anatomical_structure ,Manual Lymphatic Drainage ,chemistry ,Parasternal line ,030220 oncology & carcinogenesis ,Upper limb ,Cardiology and Cardiovascular Medicine ,business ,Indocyanine green - Abstract
Background: The Australian Lymphoedema Education, Research and Treatment Program (ALERT) at Macquarie University in Sydney, Australia is one of the flagship programs of Australia's first fully integrated academic health sciences centre, MQ Health. The aim of this study was to describe our findings of compensatory drainage demonstrated by indocyanine green (ICG) lymphography in cancer-related upper and lower limb lymphedema and how this may be translated into clinical practice. Methods and Results: Retrospective data from 339 patients aged between 18 and 90 years with secondary cancer-related unilateral or bilateral lymphedema of the upper or lower limb who underwent ICG lymphography assessment at the ALERT clinic between February 2017 and March 2020 were analyzed. In patients with upper limb lymphedema, the ipsilateral axilla was the most frequent drainage region (74.9%), followed by clavicular (41.8%) and parasternal (11.3%). For patients with mild upper limb lymphedema, 94.4% drained to the ipsilateral axilla. No patients drained to the ipsilateral inguinal region. For lower limb lymphedema, drainage to the ipsilateral inguinal was most common (52.3%), followed by contralateral inguinal (30.7%), popliteal (26.1%), and gluteal (21.6%) regions. Three main patterns of superficial lymphatic compensation were identified based on which anatomical structure carried lymph fluid. Manual lymphatic drainage (MLD) was used to facilitate movement of the dye. A light/effleurage technique was sufficient to move the dye through patent lymphatic vessels; a slow and firmer technique was required to move the dye through areas of bridging dermal backflow. Conclusion: The introduction of ICG lymphography to our program and its use in guiding personalized conservative management plans, including facilitative MLD techniques, has translated into clinical practice and changed research and educational priorities within the ALERT program.
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- 2020
18. 25 The COVID junior support team (CJST)
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Helen Mackie, Amanda Armstrong, Aimee Mallin, Yvonne Milne, and Rachel Hunter
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Service (business) ,Medical education ,Work (electrical) ,Intervention (counseling) ,media_common.quotation_subject ,Interim ,education ,Workforce ,Transferable skills analysis ,Quality (business) ,Psychology ,Autonomy ,media_common - Abstract
The NHS response to COVID 19 required staff to work very differently as the health service pivoted dramatically. As clinical service models evolved to prepare our hospital for the anticipated wave of COVID patients, a group of junior doctors who were excluded from frontline duties volunteered to contribute by providing office based tasks. The COVID Junior Support Team (CJST) was formed with its main ‘objective’, to support staff in the delivery of effective and high quality patient care. The CJST self-organised its members, taking on specific roles and setting up services tailored to address specific needs identified. Outputs included: Standard Operating Procedures (SOP) for COVID-19 results management for discharged patients Updating clinical guidance Communication cascade Rotas Induction and Training programs for interim FY1’s Mortality Reports Rapid learning reports/literature searches Staff wellbeing survey GP advice service provided by senior trainees and consultants Our intervention has shown that despite not being able to work in patient facing clinical environments doctors in training have many transferable skills which can be harnessed to assist front line staff and contribute positively. The CJST provided a unique development opportunity for doctors in training to gain experience of leadership and management across a wide range of activity. The team were empowered by senior medical leaders to work autonomously and to develop solutions, whilst ensuring they had clear and direct access to senior support. Shielding trainees may continue to part of the medical workforce for some time as we approach recovery. Our intervention shows these trainees can gain skills and experience from being involved in leadership and management roles out with the clinical environment. They can be utilised to enhance services if given autonomy and support to do so.
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- 2020
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19. 47 Doctors Administrators a novel addition to the non-medical workforce
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Sharon Scott, Jennifer Short, Claire MacDougall, Andrew Bickerstaff, Helen Mackie, and Angela Dixon
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Medical terminology ,Copying ,Data collection ,Referral ,education ,Workforce ,medicine ,Workload ,Medical emergency ,Safeguarding ,medicine.disease ,Psychology ,Bespoke - Abstract
Introduction We describe a project to introduce a novel non- medical role to support Medical staff, the ‘Doctors administrator’, and to improve the quality and timeliness of the final discharge summary letter (DSL) being sent to primary care teams. A bespoke a training program was developed which included, ward clerk duties, typing, medical terminology and coding. DAs were trained to produce DSLs, which consultants then verified or amended electronically, before forwarding to the GP. Pilot phase: 6 months 3WTE DAs produced 260 DSL each month. Two consultants acted as supervisors. This relationship was key to building confidence and capability and to ensure high quality of the letters. A very early quality indicator was the percentage of letters typed within 3 Days. Letter typed within 3 days% by consultant PRE – DA • POST –DA Consultant A • 55.4% • 67.6% Consultant B • 8.6% • 71.2% Full implementation DA’s now act on behalf of 13+ consultants producing over 550 DSL monthly. Assuming each DSL takes around 15 minutes, we estimate DA’s save around 120 hours consultant time monthly. A standardised format ensures key information is not omitted facilitating more accurate coding and data collection. Consultants and DAs are highly satisfied. Consultants felt there was less burden of basic admin tasks. ‘the time I now spend on admin has significantly reduced and is much more structured’ Feedback from GP’s was positive and improved timeliness of communication had been observed. Safety There have been 3 Clinical incidents recorded during the whole period, both related to onward results/referral management. All incidents were investigated and safeguarding actions put in place e.g. copying of onward referrals to specialist’s teams. Conclusions Doctors administrators are safe and effective and reduce clinical workload. Whilst we have utilised this resource for DSL for we believe this role could be expanded and developed in other clinical contexts.
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- 2020
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20. Work experiences of Australian cancer survivors with lymphoedema: A qualitative study
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Caleb J. Winch, John Boyages, Hector Viveros, Louise Koelmeyer, Lucy Taksa, Senia Kalfa, Paul J. Gollan, and Helen Mackie
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Adult ,Cancer survivorship ,Sociology and Political Science ,Secondary lymphoedema ,Identity (social science) ,Return to work ,Severity of Illness Index ,Interviews as Topic ,03 medical and health sciences ,Return to Work ,0302 clinical medicine ,Cancer Survivors ,Nursing ,Adaptation, Psychological ,Humans ,Lymphedema ,030212 general & internal medicine ,Qualitative Research ,integumentary system ,Interpretative phenomenological analysis ,030503 health policy & services ,Health Policy ,Australia ,Public Health, Environmental and Occupational Health ,Middle Aged ,body regions ,Scholarship ,Work (electrical) ,Female ,0305 other medical science ,Psychology ,Social Sciences (miscellaneous) ,Qualitative research - Abstract
Our qualitative study addresses a significant gap in the scholarship on return-to-work after cancer by examining the impact of secondary lymphoedema on individuals in paid employment. We undertook an Interpretive Phenomenological Analysis of interviews with 14 cancer survivors (13 women) with secondary lymphoedema in Sydney, Australia. Our interviewees were engaged in paid employment during and after their lymphoedema diagnosis. In addition to difficulties with tasks involving manual or repetitive labour, interviewees highlighted the importance of work for maintaining their identity. They also outlined the critical role that significant others at work, such as supervisors and colleagues, play in maintaining that identity. At the same time, their need for privacy and control over to whom they disclosed their lymphoedema diagnosis emerged strongly from our interviews. Finally, we present the coping mechanisms that our interviewees utilised to manage their lymphoedema in the workplace, including covering the affected limb with long sleeves, changing the tasks they completed, or even changing employers. In addition to our contribution to the scholarship, we highlight implications for employers, future research, and policy makers.
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- 2018
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21. Reducing Body Image–Related Distress in Women With Breast Cancer Using a Structured Online Writing Exercise: Results From the My Changed Body Randomized Controlled Trial
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Astrid Przezdziecki, Christopher J. Kilby, John Boyages, Elisabeth Elder, Kerry A. Sherman, Helen Mackie, Louise Koelmeyer, and Jessica Alcorso
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050103 clinical psychology ,Cancer Research ,medicine.medical_specialty ,Writing ,Psychological intervention ,Breast Neoplasms ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,Randomized controlled trial ,law ,Survivorship curve ,Body Image ,Humans ,Medicine ,0501 psychology and cognitive sciences ,Depression (differential diagnoses) ,Neoplasm Staging ,Internet ,business.industry ,05 social sciences ,Middle Aged ,Body Dysmorphic Disorders ,medicine.disease ,Psychotherapy ,Distress ,Treatment Outcome ,Lymphedema ,Oncology ,030220 oncology & carcinogenesis ,Physical therapy ,Anxiety ,Female ,medicine.symptom ,business - Abstract
Purpose Breast cancer treatment adverse effects result in one in three survivors experiencing body image–related distress (BID) that negatively impacts on a woman’s ability to recover after cancer and into survivorship. My Changed Body (MyCB) is a Web-based psychological intervention to alleviate BID and improve body appreciation in survivors of breast cancer (BCSs) through a single-session, self-compassion focused writing activity. This randomized controlled trial evaluated the impact of MyCB on BID and body appreciation in BCSs. The moderating effect of lymphedema status (affected or unaffected) and appearance investment (self-importance placed on personal appearance) and the mediating effect of self-compassion were evaluated. Patients and Methods Women (disease-free stage I to III BCSs who had experienced at least one negative event related to bodily changes after breast cancer) were randomly assigned to MyCB (n = 149) or an expressive writing control arm (n = 155). Primary outcomes were reduction in BID and improvement in body appreciation 1 week after intervention. Secondary outcomes included psychological distress (depression and anxiety) and self-compassion. Follow-up assessments occurred 1 week, 1 month, and 3 months after writing. Results Compliance with the MyCB intervention was 88%, and attrition was 9.2%. Intent-to-treat linear mixed models indicated that participants who received MyCB reported significantly less BID ( P = .035) and greater body appreciation ( P = .004) and self-compassion ( P < .001) than expressive writing participants. Intervention effects on BID were moderated by lymphedema status ( P = .007) and appearance investment ( P = .042). Self-compassion mediated effects on both primary outcomes. Therapeutic effects were maintained at 1 month (BID and body appreciation) and 3 months (body appreciation) after intervention. Significant reductions in psychological distress (1-month depression, P = .001; 1-week and 1-month anxiety, P = .007) were evident for MyCB participants with lymphedema. Conclusion This study supports the efficacy of MyCB for reducing BID and enhancing body appreciation among BCSs.
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- 2018
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22. Breast Cancer-Related Lymphedema: Differentiating Fat from Fluid Using Magnetic Resonance Imaging Segmentation
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Yuka Sen, Kevin Ho Shon, Helen Mackie, Hiroo Suami, John Boyages, Yi Qian, Robyn Ricketts, Robert Borotkanics, Thomas Lam, and Louise Koelmeyer
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medicine.medical_specialty ,Breast Cancer Lymphedema ,medicine.medical_treatment ,Adipose tissue ,Breast Neoplasms ,030230 surgery ,Bone and Bones ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,Lipectomy ,Fibrosis ,Extracellular fluid ,medicine ,Humans ,Muscle, Skeletal ,Mastectomy ,Aged ,medicine.diagnostic_test ,business.industry ,Soft tissue ,Extracellular Fluid ,Magnetic resonance imaging ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,Lymphedema ,Adipose Tissue ,030220 oncology & carcinogenesis ,Liposuction ,Female ,Lymph ,Radiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background: Lymphedema is an iatrogenic complication after breast cancer treatment in which lymph fluid in the affected limb progresses to fat deposition and fibrosis that are amenable to liposuction treatment. Magnetic resonance imaging (MRI) for lymphedema can differentiate fat tissue from fluid, but estimating relative volumes remains problematic. Methods and Results: Patients underwent routine bilateral arm MRI both before and after liposuction for advanced lymphedema. The threshold-based level set (TLS) segmentation method was applied to segment the geometric image data and to measure volumes of soft tissue (fat, muscle, and lymph fluid) and bone. Bioimpedance testing (L-Dex®) to detect extracellular fluid was also used. Volumes derived by using TLS or girth measurement were evaluated and showed consistent agreement, whereas L-Dex showed no significant reduction between pre- and postoperative measures. The percentage median volume difference between the affected and unaffected sides was 132....
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- 2018
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23. Vascularized Lymph Node Transfer for Patients with Breast Cancer-Related Lymphedema Can Potentially Reduce the Burden of Ongoing Conservative Management
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Quan Ngo, Louise Koelmeyer, Hiroo Suami, Sharon Czerniec, Asha Heydon-White, John Boyages, Sonali Munot, Thomas Lam, and Helen Mackie
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medicine.medical_specialty ,Conservative management ,medicine.medical_treatment ,Breast Cancer Lymphedema ,Breast Neoplasms ,030204 cardiovascular system & hematology ,Conservative Treatment ,03 medical and health sciences ,0302 clinical medicine ,Quality of life ,medicine ,Humans ,Surgical treatment ,Lymph node ,business.industry ,Microsurgery ,medicine.disease ,medicine.anatomical_structure ,Lymphedema ,Lymphatic system ,030220 oncology & carcinogenesis ,Female ,Radiology ,Lymph Nodes ,Cardiology and Cardiovascular Medicine ,business ,Breast Cancer Related Lymphedema - Abstract
Background: Vascularized lymph node transfer (VLNT) microsurgery is conducted in selected specialist lymphatic programs as a surgical treatment option for breast cancer-related lymphedema (BCRL) wi...
- Published
- 2020
24. A new indocyanine green fluorescence lymphography protocol for identification of the lymphatic drainage pathway for patients with breast cancer-related lymphoedema
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Louise Koelmeyer, Sharon Czerniec, Hiroo Suami, Helen Mackie, John Boyages, and Asha Heydon-White
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Indocyanine Green ,Cancer Research ,medicine.medical_specialty ,Breast Cancer Lymphedema ,Molecular imaging ,030230 surgery ,lcsh:RC254-282 ,Fluorescence ,Upper Extremity ,03 medical and health sciences ,chemistry.chemical_compound ,Manual lymphatic drainage ,0302 clinical medicine ,Breast cancer ,Genetics ,medicine ,Humans ,Prospective Studies ,Stage (cooking) ,Coloring Agents ,Lymph node ,Aged ,Lymphatic Vessels ,Retrospective Studies ,Massage ,business.industry ,Lymphography ,Middle Aged ,medicine.disease ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,Lymphatic system ,body regions ,Axilla ,medicine.anatomical_structure ,Lymphoedema ,Oncology ,chemistry ,Technical Advance ,030220 oncology & carcinogenesis ,Lymph Node Excision ,Female ,Radiology ,business ,Indocyanine green ,Lymphoscintigraphy - Abstract
Background Breast cancer related lymphoedema (BCRL) is a common side effect of cancer treatment. Recently indocyanine green (ICG) fluorescent lymphography has become a popular method for imaging the lymphatics, however there are no standard protocols nor imaging criteria. We have developed a prospective protocol to aid in the diagnosis and therapeutic management of BCRL. Methods Lymphatic imaging procedures were conducted in three phases. Following initial observation of spontaneous movement of ICG in phase one, manual lymphatic drainage (MLD) massage was applied to facilitate ICG transit via the lymphatics in phase two. All imaging data was collected in phase three. Continuous lymphatic imaging of the upper limb was conducted for approximately an hour and lymphatic drainage pathways were determined. Correlations between the drainage pathway and MD Anderson Cancer Centre (MDACC) ICG lymphoedema stage were investigated. Results One hundred and three upper limbs with BCRL were assessed with this new protocol. Despite most of the patients having undergone axillary node dissection, the ipsilateral axilla drainage pathway was the most common (67% of upper limbs). We found drainage to the ipsilateral axilla decreased as MDACC stage increased. Our results suggest that the axillary pathway remained patent for over two-thirds of patients, rather than completely obstructed as conventionally thought to be the case for BCRL. Conclusions We developed a new ICG lymphography protocol for diagnosing BCRL focusing on identification of an individual patient’s lymphatic drainage pathway after lymph node surgery. The new ICG lymphography protocol will allow a personalised approach to manual lymphatic drainage massage and potentially surgery.
- Published
- 2019
25. 'You’re naked, you’re vulnerable': Sexual well-being and body image of women with lower limb lymphedema
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John Boyages, Helen Mackie, Louise Koelmeyer, Katriona M. Smith, Caleb J. Winch, and Kerry A. Sherman
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Adult ,Coping (psychology) ,medicine.medical_specialty ,Social Psychology ,Referral ,Secondary lymphedema ,Sexual Behavior ,050109 social psychology ,Human sexuality ,03 medical and health sciences ,Social support ,0302 clinical medicine ,hemic and lymphatic diseases ,Adaptation, Psychological ,Interview, Psychological ,Body Image ,medicine ,Humans ,0501 psychology and cognitive sciences ,Lymphedema ,Buttocks ,General Psychology ,Applied Psychology ,Aged ,Leg ,business.industry ,05 social sciences ,Social Support ,Middle Aged ,medicine.disease ,Self Concept ,humanities ,body regions ,Sexual Partners ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Physical therapy ,Female ,Thematic analysis ,medicine.symptom ,business ,Clinical psychology - Abstract
Lower-limb lymphedema is an incurable illness manifesting as visible swelling enlarging the leg(s) and/or feet, buttocks, and genitals. This study used semi-structured interviews and thematic analysis to explore sexual well-being among women with primary (congenital) lymphedema (n=11) or secondary lymphedema associated with gynecological cancer (n=8). Five themes (subthemes) summarized women's responses, with Attractiveness and Confidence (Publicly Unattractive, Privately Unconfident, Lymphedema or Aging?) describing women's central concern. These body image-related concerns accounted for sexual well-being in association with Partner Support (Availability of Support, Languages of Support, Fears About Support) and the degree of Functional Interruptions (Lymphedema in Context, Enduring Impacts, Overcoming Interruptions). Successful Lymphedema Coping (Control, Acceptance) and self-perceived ability to fulfill a valued Sexual Role also affected sexual well-being. Few differences between women with primary versus secondary lymphedema were evident. Lymphedema clinicians should screen for sexual concerns and have referral options available.
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- 2016
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26. Financial cost of lymphedema borne by women with breast cancer
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Ying Xu, Hector Viveros, Lucy Taksa, Bonny Parkinson, Louise Koelmeyer, John Boyages, Senia Kalfa, Paul J. Gollan, and Helen Mackie
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Financial costs ,Finance ,business.industry ,Incidence (epidemiology) ,Cancer ,Experimental and Cognitive Psychology ,medicine.disease ,humanities ,body regions ,03 medical and health sciences ,Psychiatry and Mental health ,0302 clinical medicine ,Lymphedema ,Breast cancer ,Oncology ,hemic and lymphatic diseases ,030220 oncology & carcinogenesis ,Cellulitis ,Severity of illness ,Medicine ,030212 general & internal medicine ,business ,Subclinical infection - Abstract
Objective Our study examines the financial cost of lymphedema following a diagnosis of breast cancer and addresses a significant knowledge gap regarding the additional impact of lymphedema on breast cancer survivors. Methods An online national survey was conducted with 361 women who had either breast cancer without lymphedema (BC) (group 1, n = 209) or breast cancer with lymphedema (BC+LE) (group 2, n = 152). Participant recruitment was supported by the Breast Cancer Network Australia and the Australasian Lymphology Association. Results Both breast cancer and lymphedema result in significant out-of-pocket financial costs borne by women. Of patients with BC+LE, 80% indicated that their breast cancer diagnosis had affected them financially compared with 67% in the BC group (P
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- 2016
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27. Cryogenic Numbing to Reduce Injection Discomfort during Indocyanine Green Lymphography
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Hiroo Suami, John Boyages, Asha Heydon-White, Louise Koelmeyer, and Helen Mackie
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Indocyanine Green ,business.industry ,Coloring agents ,Lymphography ,chemistry.chemical_compound ,chemistry ,Anesthesia ,Medicine ,Humans ,Pain Management ,Surgery ,Lymphedema ,business ,Coloring Agents ,Indocyanine green ,Anesthesia, Local - Published
- 2018
28. Patterns of lymphatic drainage after axillary node dissection impact arm lymphoedema severity: A review of animal and clinical imaging studies
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Helen Mackie, Louise Koelmeyer, Hiroo Suami, and John Boyages
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medicine.medical_specialty ,Breast Neoplasms ,Dissection (medical) ,030230 surgery ,03 medical and health sciences ,0302 clinical medicine ,Image Processing, Computer-Assisted ,Medicine ,Animals ,Humans ,Lymphedema ,Vein ,Lymph node ,Mastectomy ,business.industry ,medicine.disease ,Axilla ,medicine.anatomical_structure ,Lymphatic system ,Oncology ,030220 oncology & carcinogenesis ,Arm ,Upper limb ,Drainage ,Lymph Node Excision ,Surgery ,Female ,Lymph ,Radiology ,business ,Lymphoscintigraphy - Abstract
Upper extremity lymphoedema after axillary node dissection is an iatrogenic disease particularly associated with treatment for breast or skin cancer. Anatomical studies and lymphangiography in healthy subjects identified that axillary node dissection removes a segment of the lymphatic drainage pathway running from the upper limb to the sub-clavicular vein, creating a surgical break. It is reasonable to infer that different patterns of lymphatic drainage may occur in the upper limb following surgery and contribute to the various presentations of lymphoedema from none to severe. Firstly, we reviewed animal imaging studies that investigated the repair of lymphatic drainage pathways from the limb after lymph node dissection. Secondly, we examined clinical imaging studies of lymphatic drainage pathways after axillary node dissection, including lymphangiography, lymphoscintigraphy and indocyanine green fluorescence lymphography. Finally, based on the gathered data, we devised a set of general principles for the restoration of lymphatic pathways after surgery. Lymphoscintigraphy shows that restoration of the original lymphatic pathway to the axilla after its initial disruption by nodal dissection was not uncommon and may prevent lymphoedema. We found that regenerated lymphatic vessels and dermal backflow (the reflux of lymph to the skin) contributed to either restoration of the original pathway or rerouting of the lymphatic pathway to other regional nodes. Variation in the lymphatic drainage pathway and the mechanisms of fluid drainage itself are the foundation of new lymphatic drainage patterns considered to be significant in determining the severity with which lymphoedema develops.
- Published
- 2018
29. Worse and worse off: the impact of lymphedema on work and career after breast cancer
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Louise Koelmeyer, John Boyages, Helen Mackie, Paul J. Gollan, Senia Kalfa, Hector Viveros, Lucy Taksa, and Ying Xu
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medicine.medical_specialty ,Multidisciplinary ,business.industry ,Research ,Attendance ,medicine.disease ,humanities ,Work performance ,body regions ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,Lymphedema ,Work (electrical) ,030220 oncology & carcinogenesis ,hemic and lymphatic diseases ,medicine ,Physical therapy ,030212 general & internal medicine ,business ,Prospective cohort study ,Breast Cancer Related Lymphedema ,Subclinical infection - Abstract
Purpose Our study examines the impact of breast cancer-related lymphedema on women’s work and career. Our research addresses a significant knowledge gap regarding the additional impact of lymphedema on breast cancer survivors. Methods An online national survey was conducted with 361 women who either had breast cancer without lymphedema (Group 1, n = 209) or breast cancer with lymphedema (Group 2, n = 152). Participant recruitment was supported by the Breast Cancer Network Australia and the Australasian Lymphology Association. Results Both breast cancer and lymphedema had a significant negative influence on women’s work and career. Respondents reported changes in employment resulting from stress and/or physical impairment, which affected attendance and work performance. The perceived negative impact of breast cancer on respondents’ work and career was noticeably greater in Group 2 (63 %) than Group 1 (51 %) (p = 0.03). Of the participants who were in paid employment at some time (either at diagnosis of lymphedema or at the time of the survey (n = 103), 43 (42 %) indicated that lymphedema impacted their work performance. The impact of lymphedema on work was incremental with increased severity of lymphedema (range 22–75 %). The annual number of days off work for subclinical/mild lymphedema participants was 1.4 versus 8.1 days for moderate or severe participants (p = 0.003). Conclusions This study identifies an additional detrimental effect of lymphedema on women’s work and career over and above the initial impact of breast cancer and provides empirical evidence for future prospective studies and policy improvement.
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- 2016
30. Psychosocial factors associated with adherence for self-management behaviors in women with breast cancer-related lymphedema
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Jessica Alcorso, Helen Mackie, John Boyages, Kerry A. Sherman, and Louise Koelmeyer
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Oncology ,medicine.medical_specialty ,Breast Neoplasms ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,hemic and lymphatic diseases ,Internal medicine ,Surveys and Questionnaires ,medicine ,Humans ,Psychology ,030212 general & internal medicine ,Lymphedema ,Self-management ,business.industry ,Nursing research ,Cognition ,Middle Aged ,medicine.disease ,humanities ,body regions ,Self Care ,030220 oncology & carcinogenesis ,Self care ,Female ,business ,Psychosocial ,Breast Cancer Related Lymphedema - Abstract
Cognitive and affective psychosocial factors have been found to underlie adherence to preventive behaviors in women at risk of developing lymphedema following treatment for breast cancer. The aim of this study was to determine if these factors are associated with adherence to self-management behaviors for women diagnosed with breast cancer-related lymphedema (BCRL).Women with BCRL were recruited through a community-based breast cancer organization and three Australian lymphedema treatment clinics. Participants completed an online questionnaire assessing demographics, medical history, adherence to self-management behaviors, psychosocial variables (personal control, treatment control, consequences, distress, and self-regulation of affect), and knowledge about lymphedema self-management.A total of 166 women participated in the study. Participants reported adhering to a mean of five out of seven behaviors, with 19.5% of participants adhering to all seven behaviors. Adherence to individual behaviors ranged from 65% (self-lymphatic drainage) to 98.2% (skin care). Greater knowledge about lymphedema was significantly correlated with higher adherence. Hierarchical multiple linear regression analysis indicated that only medical history factors (time since diagnosis and having undergone hormone replacement therapy) predicted a significant amount of the variance in adherence.These findings highlight the importance of patient knowledge for optimal adherence to a self-management regimen. In addition, medical history factors may identify if a patient is at risk of nonadherence. The lack of association of adherence with other psychosocial factors considered in this study indicates that factors underlying adherence in affected women differ considerably from those factors prompting preventive behavior adherence in the at-risk population.
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- 2015
31. Sexual concerns of women diagnosed with breast cancer-related lymphedema
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Katriona M. Smith, Louise Koelmeyer, John Boyages, Kerry A. Sherman, Helen Mackie, and Caleb J. Winch
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Adult ,medicine.medical_specialty ,Pain medicine ,Sexual Behavior ,Human sexuality ,Breast Neoplasms ,Interviews as Topic ,Beauty ,Breast cancer ,hemic and lymphatic diseases ,medicine ,Body Image ,Humans ,Lymphedema ,Aged ,business.industry ,Nursing research ,Middle Aged ,medicine.disease ,humanities ,body regions ,Oncology nursing ,Sexual Partners ,Oncology ,Family medicine ,Chronic Disease ,Physical therapy ,Female ,Sexual function ,business ,Breast Cancer Related Lymphedema - Abstract
Lymphedema is a common side effect of breast cancer treatment that may negatively impact on a woman's physical and psychological well-being. This study aimed to understand the impact of breast cancer-related lymphedema on women's sexual functioning, and to identify key concerns of these women regarding sexual issues.Purposive sampling recruited 17 women aged 38-67 years with mild to severe lymphedema. Telephone interviews concerning sexual issues were transcribed verbatim and thematic analysis undertaken.Women perceived sexual concerns arising from lymphedema to exacerbate concerns arising from breast cancer. Four interrelated factors determined the extent of lymphedema's sexual impact: (a) swelling severity and location, (b) needing to wear a compression garment, (c) body image concerns raised by lymphedema and breast cancer treatment, and (d) their sexual partner's acceptance and supportiveness. In particular, a supportive partner was instrumental in assisting women to overcome sexual issues caused by severe swelling and/or body image concerns. Few women reported being asked about sexual issues by any health professional, and most women indicated that they were unwilling to discuss sexual concerns with health professionals, friends, or family.Lymphedema had the potential to accentuate sexual issues caused by breast cancer, but most women were reluctant to discuss issues with anyone other than their partner. These findings are relevant to health professionals designing breast cancer psychosexual interventions and future research addressing lymphedema-specific sexual concerns.
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- 2014
32. Liposuction for advanced lymphoedema – Impact of liposuction on limb volumes. Surgical treatment results from Australia
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Kerry A. Sherman, Asha Heydon-White, Caleb J. Winch, John Boyages, Thomas Lam, Louise Koelmeyer, John Magnussen, Quan Ngo, Katrina Kastanias, Lisa M. Sedger, Alex Munnoch, and Helen Mackie
- Subjects
medicine.medical_specialty ,business.industry ,Gold coast ,Liposuction ,medicine.medical_treatment ,medicine ,Surgery ,General Medicine ,Creative commons ,Surgical treatment ,business - Abstract
presented at the Australian Breast Congress, 9-11 October 2014, Gold Coast, Australia. Abstract published online at 10.1016/j.breast.2015.02.005published online at 10.1016/j.breast.2015.02.005 © 2015, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/
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- 2015
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33. The influence of pre-admission diet upon liver function tests of patients with acuta alcehelic hepatitis
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Aillen Galloway, Ewan Forrest, John C. Morris, Helen Mackie, and Harry Suzuki
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Hepatitis ,medicine.medical_specialty ,medicine.diagnostic_test ,Hepatology ,business.industry ,Internal medicine ,medicine ,Gastroenterology ,Liver function tests ,business ,medicine.disease - Published
- 2001
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34. Relationship of carotenoid and vitamins A and E with the acute inflammatory response in acute alcoholic hepatitis
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Naveed Sattar, Dinesh Talwar, Harry Suzuki, John C. Morris, Helen Mackie, and Ewan Forrest
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chemistry.chemical_classification ,chemistry ,Hepatology ,business.industry ,Inflammatory response ,Immunology ,Gastroenterology ,Medicine ,business ,Acute Alcoholic Hepatitis ,Carotenoid - Published
- 2001
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35. Liposuction for advanced lymphoema
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Lam, Thomas C., Katrina Kastanias, Louise Koelmeyer, Helen Mackie, Lisa Sedger, and quan ngo
36. Perceived barriers to adherence to breast cancer-related lymphoedema self-management
- Author
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Jessica Alcorso, Kerry Sherman, Louise Koelmeyer, Helen Mackie, and John Boyages
37. Is lymphatic reconstitution possible after meshed skin grafting?
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quan ngo, Hiroo Suami, Louise Koelmeyer, Helen Mackie, Sonali Munot, Asha Heydon-White, and John Boyages
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Lymphatic System ,Humans ,Lymphography ,Female ,Fasciitis, Necrotizing ,Skin Transplantation ,Lymphangiogenesis ,Skin Diseases ,Aged - Abstract
Restorative potential of lymph transport after skin graft has rarely been discussed. We report a case of lymphatic reconstitution across meshed, split-thickness skin graft performed for a patient with necrotizing fasciitis. The patient underwent extensive circumferential soft tissue debridement of the lower leg and resurfacing of the skin defect with meshed split-thickness skin graft. Indocyanine green fluorescence lymphography was performed 3 years after surgery and demonstrated that injected dye in the foot traveled across the skin graft and reached to the adjacent native skin in the proximal region. Our observation revealed that transferred split-thickness skin graft possessed some potential to allow for transport of lymph fluid possibly owing to the retention of lymphatic capillaries.
38. Surgical approaches for the management of lymphedema
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John Boyages, Lam, Thomas C., quan ngo, Louise Koelmeyer, Helen Mackie, and Hiroo Suami
39. Reducing Body Image-Related Distress in Women With Breast Cancer Using a Structured Online Writing Exercise: Results From the My Changed Body Randomized Controlled Trial.
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Sherman KA, Przezdziecki A, Alcorso J, Kilby CJ, Elder E, Boyages J, Koelmeyer L, and Mackie H
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- Body Dysmorphic Disorders etiology, Body Dysmorphic Disorders psychology, Body Image psychology, Breast Neoplasms pathology, Female, Humans, Internet, Middle Aged, Neoplasm Staging, Treatment Outcome, Writing, Body Dysmorphic Disorders therapy, Breast Neoplasms psychology, Breast Neoplasms therapy, Psychotherapy methods
- Abstract
Purpose Breast cancer treatment adverse effects result in one in three survivors experiencing body image-related distress (BID) that negatively impacts on a woman's ability to recover after cancer and into survivorship. My Changed Body (MyCB) is a Web-based psychological intervention to alleviate BID and improve body appreciation in survivors of breast cancer (BCSs) through a single-session, self-compassion focused writing activity. This randomized controlled trial evaluated the impact of MyCB on BID and body appreciation in BCSs. The moderating effect of lymphedema status (affected or unaffected) and appearance investment (self-importance placed on personal appearance) and the mediating effect of self-compassion were evaluated. Patients and Methods Women (disease-free stage I to III BCSs who had experienced at least one negative event related to bodily changes after breast cancer) were randomly assigned to MyCB (n = 149) or an expressive writing control arm (n = 155). Primary outcomes were reduction in BID and improvement in body appreciation 1 week after intervention. Secondary outcomes included psychological distress (depression and anxiety) and self-compassion. Follow-up assessments occurred 1 week, 1 month, and 3 months after writing. Results Compliance with the MyCB intervention was 88%, and attrition was 9.2%. Intent-to-treat linear mixed models indicated that participants who received MyCB reported significantly less BID ( P = .035) and greater body appreciation ( P = .004) and self-compassion ( P < .001) than expressive writing participants. Intervention effects on BID were moderated by lymphedema status ( P = .007) and appearance investment ( P = .042). Self-compassion mediated effects on both primary outcomes. Therapeutic effects were maintained at 1 month (BID and body appreciation) and 3 months (body appreciation) after intervention. Significant reductions in psychological distress (1-month depression, P = .001; 1-week and 1-month anxiety, P = .007) were evident for MyCB participants with lymphedema. Conclusion This study supports the efficacy of MyCB for reducing BID and enhancing body appreciation among BCSs.
- Published
- 2018
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