170 results on '"Heldreth B"'
Search Results
2. Increasing the availability of high quality regulatory and toxicity data through the COSMOS DB DataShare Point
- Author
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Cronin, M.T., primary, Yang, C., additional, Arvidson, K., additional, Boyer, I., additional, Fioravanzo, E., additional, Heldreth, B., additional, Kim, J.H., additional, Madden, J.C., additional, Rathman, J., additional, Schwab, C., additional, Yamada, T., additional, and Worth, A.P., additional
- Published
- 2016
- Full Text
- View/download PDF
3. COSMOS DB as an international share point for exchanging regulatory and toxicity data of cosmetics ingredients and related substances
- Author
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Yang, C., primary, Hristozov, D., additional, Tarkhov, A., additional, Kleinöder, T., additional, Boyer, I., additional, Cronin, M., additional, Fioravanzo, E., additional, Kim, H., additional, Heldreth, B., additional, Mostrag-Szylchtying, A., additional, Rathman, J., additional, Richarz, A., additional, Schwab, C., additional, Vitcheva, V., additional, and Worth, A., additional
- Published
- 2015
- Full Text
- View/download PDF
4. Microbiological Properties and Modes of Action of Organosulfur-based Anti-infectives
- Author
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Heldreth, B., primary and Turos, E., additional
- Published
- 2005
- Full Text
- View/download PDF
5. Safety Assessment of Methylxanthines as Used in Cosmetics.
- Author
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Cherian PA, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Humans, Animals, Caffeine toxicity, Caffeine pharmacokinetics, Theobromine toxicity, Theophylline toxicity, Theophylline pharmacokinetics, Risk Assessment, Toxicity Tests, Xanthines toxicity, Cosmetics toxicity, Cosmetics chemistry, Consumer Product Safety
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of three methylxanthines, Caffeine, Theobromine, and Theophylline, as used in cosmetics. All of these ingredients are reported to function as skin-conditioning agents in cosmetic products. The Panel reviewed the data relevant to the safety of these ingredients and concluded that Caffeine, Theobromine, and Theophylline are safe in cosmetics in the present practices of use and concentration described in this safety assessment., Competing Interests: Declaration of Conflicting InterestThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
6. Safety Assessment of Polyol Phosphates as Used in Cosmetics.
- Author
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Johnson W Jr, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Humans, Animals, Phosphates toxicity, Phosphates chemistry, Polymers toxicity, Polymers chemistry, Toxicity Tests, Risk Assessment, Cosmetics toxicity, Cosmetics chemistry, Consumer Product Safety
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 10 polyol phosphates. Some of the possible functions in cosmetics that are reported for this ingredient group are chelating agents, oral care agents, and skin conditioning agents. The Panel reviewed relevant data relating to the safety of these ingredients under the intended conditions of use in cosmetic formulations, and concluded that Sodium Phytate, Phytic Acid, Phytin, and Trisodium Inositol Triphosphate are safe in cosmetics in the present practices of use and concentration described in the safety assessment. The Panel also concluded that the data are insufficient to determine the safety of the following 6 ingredients as used in cosmetics: Disodium Glucose Phosphate, Manganese Fructose Diphosphate, Sodium Mannose Phosphate, Trisodium Fructose Diphosphate, Xylityl Phosphate, and Zinc Fructose Diphosphate., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
7. Sodium Dehydroacetate and Dehydroacetic Acid.
- Author
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Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Rettie AE, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, and Heldreth B
- Subjects
- Humans, Animals, Consumer Product Safety, Risk Assessment, Toxicity Tests, Pyrones, Cosmetics toxicity, Cosmetics chemistry, Cosmetics pharmacokinetics
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) first published a safety assessment of Sodium Dehydroacetate and Dehydroacetic Acid in 1985. The Panel previously concluded that Sodium Dehydroacetate and Dehydroacetic Acid are safe as used in the present practices of use and concentration, as stated in that report. Upon re-review in 2003, the Panel reaffirmed the original conclusion, as published in 2006. The Panel reviewed updated frequency and concentration of use data again in 2023, in addition to any newly available, relevant safety data. Considering this information, as well as the information provided in the original safety assessment and the prior re-review document, the Panel reaffirmed the 1985 conclusion., Competing Interests: Declaration of Conflicting InterestThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
8. Safety Assessment of Alkanoyl Lactyl Lactate Salts as Used in Cosmetics.
- Author
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Johnson W Jr, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Humans, Animals, Risk Assessment, Lactates toxicity, Lactates chemistry, Toxicity Tests, Surface-Active Agents toxicity, Surface-Active Agents chemistry, Surface-Active Agents pharmacokinetics, Cosmetics toxicity, Cosmetics chemistry, Consumer Product Safety
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 10 alkanoyl lactyl lactate salts. These ingredients have the surfactant function in cosmetics in common. The Panel reviewed data relevant to the safety of these ingredients, and concluded that these 10 ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment when formulated to be nonirritating and nonsensitizing, which may be based on a quantitative risk assessment (QRA) or other accepted methodologies., Competing Interests: Declaration of Conflicting InterestThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
9. Safety Assessment of Vinylpyrrolidone Polymers as Used in Cosmetics.
- Author
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Johnson W Jr, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Humans, Animals, Toxicity Tests, Risk Assessment, Cosmetics toxicity, Cosmetics chemistry, Consumer Product Safety, Polymers toxicity, Polymers chemistry, Pyrrolidinones toxicity, Pyrrolidinones chemistry, Pyrrolidinones pharmacokinetics
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 30 vinylpyrrolidone polymers as used in cosmetic products; most of these ingredients have the reported cosmetic function of film former in common. The Panel reviewed data relevant to the safety of these ingredients, and determined that 27 vinylpyrrolidone polymers are safe in cosmetics in the present practices of use and concentration described in the safety assessment. The Panel also concluded that the available data are insufficient to make a determination that 3 vinylpyrrolidone polymers (all urethanes) are safe under the intended conditions of use in cosmetic formulations., Competing Interests: Declaration of Conflicting InterestThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
10. Safety Assessment of Hydrogen Peroxide as Used in Cosmetics.
- Author
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Becker LC, Cherian PA, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Humans, Animals, Risk Assessment, Toxicity Tests, Oxidants toxicity, Hydrogen Peroxide toxicity, Cosmetics toxicity, Cosmetics chemistry, Consumer Product Safety
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Hydrogen Peroxide for use in cosmetics. This ingredient is reported to function in cosmetics as an antimicrobial agent, cosmetic biocide, oral health care agent, and oxidizing agent. The Panel reviewed the data relevant to the safety of this ingredient and concluded that Hydrogen Peroxide is safe in cosmetics in the present practices of use and concentration described in this safety assessment., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
11. Safety Assessment of Polysilicone-11 as Used in Cosmetics.
- Author
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Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Liebler DC, Marks JG, Peterson LA, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Humans, Animals, Risk Assessment, Toxicity Tests, Silicones toxicity, Silicones chemistry, Cosmetics toxicity, Cosmetics chemistry, Consumer Product Safety
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Polysilicone-11 as used in cosmetic formulations. This ingredient is reported to function as a film former. The Panel considered the available data and concluded that Polysilicone-11 is safe in cosmetics in the present practices of use and concentration described in this safety assessment., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
12. Safety Assessment of Palm-Derived Ingredients as Used in Cosmetics.
- Author
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Johnson W Jr, Bergfeld WF, Belsito DV, Klaassen CD, Liebler DC, Marks JG Jr, Peterson LA, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Humans, Animals, Euterpe chemistry, Euterpe toxicity, Toxicity Tests, Risk Assessment, Cosmetics toxicity, Cosmetics chemistry, Consumer Product Safety
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 8 palm tree ( Euterpe edulis (juçara) and Euterpe oleracea (açaí))-derived ingredients as used in cosmetic products; these ingredients are reported to function mostly as skin conditioning agents. The Panel reviewed relevant data relating to the safety of these ingredients in cosmetic formulations. Industry should continue to use good manufacturing practices to limit impurities. The Panel concluded that palm tree (açaí and juçara)-derived ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
13. Safety Assessment of Basic Red 76 as Used in Cosmetics.
- Author
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Cherian P, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Animals, Humans, Rats, Risk Assessment, Toxicity Tests, Consumer Product Safety, Cosmetics toxicity, Cosmetics chemistry, Hair Dyes toxicity, Hair Dyes chemistry, Hair Dyes pharmacokinetics
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Basic Red 76, which is reported to function in cosmetics as a hair colorant and hair-conditioning agent. The Panel reviewed the available data to determine the safety of this ingredient. The Panel concluded that Basic Red 76 is safe for use as a hair dye ingredient in the present practices of use and concentration described in the safety assessment., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
14. Safety Assessment of Hydroxyethyl Urea as Used in Cosmetics.
- Author
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Akinsulie A, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Animals, Humans, Risk Assessment, Toxicity Tests, Consumer Product Safety, Cosmetics toxicity, Cosmetics chemistry, Cosmetics pharmacokinetics, Urea analogs & derivatives, Urea toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Hydroxyethyl Urea, which is reported to function as a humectant and a hair and skin conditioning agent. The Panel reviewed the available data to determine the safety of this ingredient. The Panel concluded that Hydroxyethyl Urea is safe in cosmetics in the present practices of use and concentration described in the safety assessment when formulated to be non-irritating., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
15. Zinc Phenolsulfonate.
- Author
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Tucker R, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Rettie A, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, and Heldreth B
- Subjects
- Animals, Humans, Consumer Product Safety, Organometallic Compounds toxicity, Risk Assessment, Toxicity Tests, Cosmetics toxicity, Cosmetics chemistry, Zinc chemistry, Zinc toxicity, Sulfates chemistry, Sulfates toxicity, Phenols chemistry, Phenols toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 1986 and a previous re-review in 2004, along with updated information regarding product types and concentrations of use. Considering this information, the Panel confirmed that Zinc Phenolsulfonate is safe as a cosmetic ingredient in the present practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
16. Safety Assessment of Capryloyl Salicylic Acid as Used in Cosmetics.
- Author
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Johnson W Jr, Bergfeld WF, Belsito DV, Klaassen CD, Liebler DC, Marks JG Jr, Peterson LA, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Animals, Humans, Risk Assessment, Salicylic Acid toxicity, Salicylic Acid pharmacokinetics, Salicylic Acid chemistry, Toxicity Tests, Consumer Product Safety, Cosmetics toxicity, Cosmetics chemistry, Salicylates toxicity, Salicylates pharmacokinetics
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) reassessed the safety of Capryloyl Salicylic Acid in cosmetic products; this ingredient is reported to function as a skin conditioning agent. The Panel reviewed relevant data relating to the safety of this ingredient in cosmetic formulations, and concluded that the available data are insufficient to make a determination that Capryloyl Salicylic Acid is safe under the intended conditions of use in cosmetic formulations., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
17. Laneth Acetates.
- Author
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Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Rettie A, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, and Heldreth B
- Subjects
- Animals, Humans, Consumer Product Safety, Acetates toxicity, Acetates pharmacokinetics, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 1982 and a previous re-review in 2002, along with updated information regarding product types and concentrations of use. Considering this information, the Panel confirmed that Laneth-9 Acetate and Laneth-10 Acetate are safe for topical application to humans in the present practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
18. Safety Assessment of Triphenyl Phosphate as Used in Cosmetics.
- Author
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Burnett CL, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Triphenyl Phosphate, which is reported to function as a plasticizer in manicuring products. The Panel reviewed the available data to determine the safety of this ingredient. The Panel concluded that Triphenyl Phosphate is safe in cosmetics in the present practices of use and concentration described in this safety assessment., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
19. Isobutane, Isopentane, Butane, and Propane.
- Author
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Tucker R, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Rettie AE, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, and Heldreth B
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) first published the Final Report of the safety of Isobutane, Isopentane, Butane, and Propane in 1982. The Panel previously concluded that these ingredients are considered safe as cosmetic ingredients under the present conditions of concentration and use, as described in that safety assessment. Upon re-review in 2002, the Panel reaffirmed the original conclusion, as published in 2005. The Panel reviewed update frequency and concentration of use data again in 2023, in addition to newly available, relevant safety data. Considering this information, as well as the information provided in the original safety assessment and the prior re-review document, the Panel reaffirmed the 1982 conclusion for Isobutane, Isopentane, Butane, and Propane., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
20. Safety Assessment of Alkane Diols as Used in Cosmetics.
- Author
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Scott LN, Fiume M, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, and Heldreth B
- Subjects
- Alcohols, Solvents, Risk Assessment, Consumer Product Safety, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 10 alkane diol ingredients as used in cosmetics. The alkane diols are structurally related to each other as small diols, and most are reported to function in cosmetics as solvents. The Panel reviewed the relevant data for these ingredients, and concluded that seven alkane diols are safe in cosmetics in the present practices of use and concentration described in this safety assessment, but that the available data are insufficient to make a determination of safety for three ingredients, namely 1,4-Butanediol, 2,3-Butanediol, and Octanediol., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2024
- Full Text
- View/download PDF
21. Safety Assessment of Zinc Salts as Used in Cosmetics.
- Author
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Scott LN, Fiume M, Zhu J, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, and Heldreth B
- Subjects
- Salts, Consumer Product Safety, Chelating Agents toxicity, Risk Assessment, Cosmetics toxicity, Dermatologic Agents
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 27 inorganic and organometallic zinc salts as used in cosmetic formulations; these salts are specifically of the
2+ (II) oxidation state cation of zinc. These ingredients included in this report have various reported functions in cosmetics, including hair conditioning agents, skin conditioning agents, cosmetic astringents, cosmetic biocides, preservatives, oral care agents, buffering agents, bulking agents, chelating agents, and viscosity increasing agents. The Panel reviewed the relevant data for these ingredients, and concluded that these 27 ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.- Published
- 2024
- Full Text
- View/download PDF
22. Safety Assessment of Soy-Derived Ingredients as Used in Cosmetics.
- Author
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Cherian P, Bergfeld WF, Belsito DV, Klaassen CD, Liebler DC, Marks JG Jr, Peterson LA, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 28 soy-derived ingredients as used in cosmetic products. These ingredients are reported to primarily function as antioxidants, skin protectants, skin-conditioning agents, and hair-conditioning agents. The Panel considered the available data relating to the safety of these ingredients in cosmetic formulations, and concluded that 24 of the 28 soy-derived ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment. The Panel also concluded that the available data are insufficient to make a determination that Glycine Max (Soybean) Callus Culture, Glycine Max (Soybean) Callus Culture Extract, Glycine Max (Soybean) Callus Extract, and Glycine Max (Soybean) Phytoplacenta Conditioned Media are safe under the intended conditions of use in cosmetic formulations., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2024
- Full Text
- View/download PDF
23. Safety Assessment of Alkyl Sultaines as Used in Cosmetics.
- Author
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Burnett CL, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Skin, Surface-Active Agents, Risk Assessment, Consumer Product Safety, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 13 alkyl sultaines, which are most frequently reported to function in cosmetics as antistatic agents, surfactants, and skin and hair conditioning agents. The Panel reviewed the available data to determine the safety of these ingredients. The Panel noted gaps in the available safety data for some of the alkyl sultaines in this safety assessment; the available data on some of the ingredients are sufficient, however, and can be read across to support the safety of other members of the group. The Panel concluded that these alkyl sultaines are safe in cosmetics in the present practices of use and concentration described in this safety assessment., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2024
- Full Text
- View/download PDF
24. Safety Assessment of Trialkyl Trimellitates as Used in Cosmetics.
- Author
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Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Gill LJ, and Heldreth B
- Subjects
- Consumer Product Safety, Esters, Risk Assessment, Cosmetics toxicity, Dermatologic Agents
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 5 trialkyl trimellitates. These ingredients, which are all structurally related as alkyl esters of trimellitic acid, are reported to function in cosmetics as skin conditioning agents; 2 of the ingredients are also reported to function in cosmetics as plasticizers. The Panel reviewed the available data to determine the safety of these ingredients, and concluded that the trialkyl trimellitates are safe in the current practices of use and concentration when formulated to be non-irritating., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2024
- Full Text
- View/download PDF
25. Safety Assessment of Butyrospermum parkii (Shea)-Derived Ingredients as Used in Cosmetics.
- Author
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Burnett CL, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Consumer Product Safety, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 13 Butyrospermum parkii (shea)-derived ingredients, which are most frequently reported to function in cosmetics as skin and hair conditioning agents. The Panel reviewed the available data to determine the safety of these ingredients. Because final product formulations may contain multiple botanicals, each containing similar constituents of concern, formulators are advised to be aware of these constituents and to avoid reaching levels that may be hazardous to consumers. Industry should use good manufacturing practices to limit impurities that could be present in botanical ingredients. The Panel concluded that these ingredients are safe in the present practices of use and concentration when formulated to be non-sensitizing., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2024
- Full Text
- View/download PDF
26. Safety Assessment of Hops as Used in Cosmetics.
- Author
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Becker L, Boyer I, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Consumer Product Safety, Plant Extracts toxicity, Humulus, Biological Products, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Humulus Lupulus (Hops) Extract (reported functions include antimicrobial agent and hair conditioning agent) and Humulus Lupulus (Hops) Oil (reported function is fragrance). The Panel reviewed the relevant data related to these ingredients. Because final product formulations may contain multiple botanicals, each containing the same constituents of concern, formulators are advised to be aware of these constituents and to avoid reaching levels that may be hazardous to consumers. For these ingredients, the Panel was concerned about the presence of 8-prenylnaringenin, β-myrcene, and quercetin in cosmetics, which could result in estrogenic effects, dermal irritation, and genotoxicity, respectively. Industry should use current good manufacturing practices to limit impurities and constituents of concern. The Panel concluded that Humulus Lupulus (Hops) Extract and Humulus Lupulus (Hops) Oil are safe in cosmetics in the present practices of use and concentration when formulated to be non-sensitizing., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2024
- Full Text
- View/download PDF
27. Safety Assessment of Ginkgo biloba -Derived Ingredients as Used in Cosmetics.
- Author
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Burnett CL, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Consumer Product Safety, Plant Extracts toxicity, Antioxidants, Ginkgo biloba toxicity, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 10 Ginkgo biloba -derived ingredients, which are most frequently reported to function in cosmetics as skin conditioning agents or antioxidants. The Panel reviewed the available data to determine the safety of these ingredients. Because final product formulations may contain multiple botanicals, each containing the same constituents of concern, formulators are advised to be aware of these constituents and to avoid reaching levels that may be hazardous to consumers. The Panel was concerned about the presence of ginkgolic acid in cosmetics. Industry should use good manufacturing practices to limit impurities. The Panel concluded that 5 Ginkgo biloba leaf-derived ingredients are safe in the present practices of use and concentration described in this safety assessment when formulated to be non-sensitizing; data are insufficient to determine the safety of the remaining 5 ingredients under the intended conditions of use in cosmetic formulations., Competing Interests: Declaration of conflicting interestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Cosmetic Ingredient Review.
- Published
- 2024
- Full Text
- View/download PDF
28. Safety Assessment of Adenosine as Used in Cosmetics.
- Author
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Cherian P, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Consumer Product Safety, Adenosine Triphosphate, Risk Assessment, Adenosine toxicity, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Adenosine, Adenosine Phosphate, Adenosine Triphosphate, Disodium Adenosine Phosphate, and Disodium Adenosine Triphosphate. These ingredients are reported to function in cosmetics as skin-conditioning agents - miscellaneous. The Panel considered the available data and concluded that the five adenosine ingredients reviewed in this report are safe in cosmetics in the present practices of use and concentration described in this safety assessment., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2024
- Full Text
- View/download PDF
29. Aluminum Starch Octenylsuccinate.
- Author
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Akinsulie A, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Aluminum, Starch toxicity, Succinates toxicity, Consumer Product Safety, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 2002, along with updated information regarding product types and concentrations of use, and confirmed that Aluminum Starch Octenylsuccinate is safe as a cosmetic ingredient in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
30. Methacrylate Ester Monomers.
- Author
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Johnson W Jr, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Liebler DC, Marks JG, Peterson LA, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Methacrylates toxicity, Skin, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 2005, along with updated information regarding product types and concentrations of use, and confirmed that these 22 methacrylate ester monomers are safe as used in nail enhancement products in the practices of use and concentration as described in this report, when skin contact is avoided., Competing Interests: Declaration of Conflicting InterestThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2023
- Full Text
- View/download PDF
31. Imidazolidinyl Urea.
- Author
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Burnett C, Bergfeld WF, Belsito DV, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Consumer Product Safety, Urea, Cosmetics
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed updated information that has become available since their original assessment from 1980, along with updated information regarding product types, and frequency and concentrations of use, and reaffirmed their original conclusion that Imidazolidinyl Urea is safe as a cosmetic ingredient in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2023
- Full Text
- View/download PDF
32. Acid Orange 3.
- Author
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Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Liebler DC, Rettie AE, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, and Heldreth B
- Subjects
- Consumer Product Safety, Cosmetics toxicity, Hair Dyes toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed updated information that has become available since their original assessment from year 2000, along with updated information regarding product types, and frequency and concentrations of use, and reaffirmed their original conclusion that Acid Orange 3 is safe for use in hair dye formulations at concentrations <.2%., Competing Interests: Declaration of Conflicting InterestThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2023
- Full Text
- View/download PDF
33. HC Yellow 5.
- Author
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Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Liebler DC, Rettie AE, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, and Heldreth B
- Subjects
- Consumer Product Safety, Cosmetics toxicity, Hair Dyes toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed updated information that has become available since their original assessment from 2007, along with updated information regarding product types, and frequency and concentrations of use, and reaffirmed their original conclusion that HC Yellow 5 is safe as a hair dye ingredient in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
34. Acetyl Trialkyl Citrates.
- Author
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Johnson W, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Citrates, Consumer Product Safety, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 2002, along with updated information regarding product types and concentrations of use, and confirmed that Acetyl Triethyl Citrate, Acetyl Tributyl Citrate, Acetyl Triethylhexyl Citrate, and Acetyl Trihexyl Citrate are safe as cosmetic ingredients in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
35. Polyacrylamide.
- Author
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Raj PS, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Liebler DC, Rettie AE, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, and Heldreth B
- Subjects
- Acrylic Resins toxicity, Consumer Product Safety, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed updated information that has become available since their original assessment from 1991, along with updated information regarding product types, and frequency and concentrations of use, and reaffirmed their original conclusion that Polyacrylamide is safe as a cosmetic ingredient in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
36. Safety Assessment of Polyfluorinated Polymers as Used in Cosmetics.
- Author
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Johnson W Jr, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Consumer Product Safety, Polytetrafluoroethylene, Risk Assessment, Polymers toxicity, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 12 polyfluorinated polymers in cosmetic products; most of these ingredients have the reported function of film former in common. However, PTFE, the only ingredient that is reported as currently used in cosmetics, functions as a bulking agent and slip modifier, but not as a film former. The Panel reviewed data relevant to the safety of these ingredients under the intended conditions of use in cosmetic formulations, and concluded that PTFE and Hexafluoropropylene/Tetrafluoroethylene Copolymer are safe in cosmetics in the present practices of use and concentration described in the safety assessment; the data are insufficient to determine the safety of the 4 fluorinated-side-chain polymers and 6 fluorinated polyethers., Competing Interests: Declaration of conflicting interestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
37. Sodium α-Olefin Sulfonates.
- Author
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Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Gill LJ, Fiume M, and Heldreth B
- Subjects
- Alkenes, Sodium, Consumer Product Safety, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 1998, along with updated information regarding product types and concentrations of use, and confirmed that sodium α-olefin sulfonates are safe as cosmetic ingredients in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
38. Quaternium-26.
- Author
-
Johnson W Jr, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Consumer Product Safety, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in year 2000, along with updated information regarding product types and concentrations of use, and confirmed that sodium Quaternium-26 is safe as a cosmetic ingredient in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
39. Glyoxal.
- Author
-
Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Consumer Product Safety, Glyoxal toxicity, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed information that has become available since their year 2000 assessment, along with updated information regarding product types, and frequency and concentrations of use, and reaffirmed their original conclusion that Glyoxal is safe for use in products intended to be applied to the nail at concentrations ≤1.25% and that the available data are insufficient to support the safety for other uses., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2023
- Full Text
- View/download PDF
40. Amended Safety Assessment of Mentha piperita (Peppermint)-Derived Ingredients as Used in Cosmetics.
- Author
-
Johnson W, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Consumer Product Safety, Plant Extracts toxicity, Allergens, Mentha piperita, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of M piperita (peppermint)-derived ingredients. The Panel reviewed data relevant to the safety of these ingredients. Because final product formulations may contain multiple botanicals, each containing the same constituent(s) of concern, formulators are advised to be aware of these constituents and avoid reaching levels that may be hazardous to consumers. Industry should continue to use good manufacturing practices to limit impurities that could be present in botanical ingredients. The Panel concluded that M piperita (Peppermint) Oil, Extract, Leaf, and leaf-derived ingredients are safe in cosmetics in the present practices of use and concentration when formulated to be non-sensitizing, and that the available data are insufficient for determining that M piperita (Peppermint) Flower/Leaf/Stem Extract, M piperita (Peppermint) Flower/Leaf/Stem Water, and M piperita (Peppermint) Meristem Cell Culture are safe under the intended conditions of use in cosmetic formulations.
- Published
- 2023
- Full Text
- View/download PDF
41. Glyceryl Diesters.
- Author
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Raj PS, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Liebler DC, Rettie AE, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, and Heldreth B
- Subjects
- Toxicity Tests, Consumer Product Safety, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 2002, along with updated information regarding product types and concentrations of use, and confirmed that these 17 glyceryl diesters are safe as cosmetic ingredients in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
42. Hexamidine and Hexamidine Diisethionate.
- Author
-
Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Liebler DC, Rettie AE, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, and Heldreth B
- Subjects
- Benzamidines, Consumer Product Safety, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 2007, along with updated information regarding product types and concentrations of use, and confirmed that Hexamidine and Hexamidine Diisethionate are safe as cosmetic ingredients in the practices of use and concentration as described in this report if used at concentrations less than or equal to .10%., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
43. Cottonseed Glyceride and Hydrogenated Cottonseed Glyceride.
- Author
-
Raj PS, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Liebler DC, Rettie AE, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, and Heldreth B
- Subjects
- Cottonseed Oil, Consumer Product Safety, Toxicity Tests, Glycerides, Gossypol, Cosmetics
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 2001, along with updated information regarding product types and concentrations of use, and confirmed that Cottonseed Glyceride and Hydrogenated Cottonseed Glyceride are safe as cosmetic ingredients in the practices of use and concentration as described in this report, provided that established and imposed limits on gossypol, heavy metals, and pesticide concentrations are not exceeded., Competing Interests: Declaration of conflicting interestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
44. BHT - Butylated Hydroxytoluene.
- Author
-
Burnett C, Bergfeld WF, Belsito DV, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Butylated Hydroxyanisole, Antioxidants, Butylated Hydroxytoluene toxicity, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed updated information that has become available since their original assessment from 2002, along with updated information regarding product types, and frequency and concentrations of use, and reaffirmed their original conclusion that BHT is safe as a cosmetic ingredient in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
45. EDTA and Salts.
- Author
-
Cherian P, Bergfeld WF, Belsito DV, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Edetic Acid toxicity, Consumer Product Safety, Salts, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 1998, along with updated information regarding product types and concentrations of use and confirmed that EDTA and certain salts are safe as cosmetic ingredients in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
46. Triacetin.
- Author
-
Fiume M, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, and Heldreth B
- Subjects
- Consumer Product Safety, Triacetin, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed updated information that has become available since their original assessment from 2003, along with updated information regarding product types, and frequency and concentrations of use, and reaffirmed their original conclusion that Triacetin is safe as a cosmetic ingredient in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
47. Sulfites.
- Author
-
Johnson W Jr, Bergfeld WF, Belsito DV, Klaassen CD, Liebler DC, Marks JG, Peterson LA, Shank RC, Slaga TJ, Snyder PW, Fiume M, and Heldreth B
- Subjects
- Sulfites toxicity, Consumer Product Safety, Quaternary Ammonium Compounds, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 1998, along with updated information regarding product types and concentrations of use, and confirmed that Sodium Sulfite, Potassium Sulfite, Ammonium Sulfite, Sodium Bisulfite, Ammonium Bisulfite, Sodium Metabisulfite, and Potassium Metabisulfite are safe as cosmetic ingredients in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
48. Glycol Stearate and Glycol Stearate SE.
- Author
-
Tucker R, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Liebler DC, Rettie AE, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, and Heldreth B
- Subjects
- Stearates toxicity, Consumer Product Safety, Surface-Active Agents, Glycols, Toxicity Tests, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 1982, along with updated information regarding product types and concentrations of use, and confirmed that Glycol Stearate and Glycol Stearate SE are safe as cosmetic ingredients in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2023
- Full Text
- View/download PDF
49. Choleth-24.
- Author
-
Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Rettie AE, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, and Heldreth B
- Subjects
- Humans, Polyethylene Glycols, Consumer Product Safety, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed updated information that has become available since their original assessment from 1982, along with updated information regarding product types, and frequency and concentrations of use, and reaffirmed their original conclusion that Choleth-24 is safe for topical applications to humans in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
50. Mink Oil.
- Author
-
Tucker R, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Liebler DC, Rettie AE, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, and Heldreth B
- Subjects
- Glycerides, Consumer Product Safety, Cosmetics toxicity
- Abstract
The Expert Panel for Cosmetic Ingredient Safety reviewed updated information that has become available since their original assessment from 1998, along with updated information regarding product types, and frequency and concentrations of use, and reaffirmed their original conclusion that Mink Oil is safe as a cosmetic ingredient in the practices of use and concentration as described in this report., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The articles in this supplement were sponsored by the Cosmetic Ingredient Review.
- Published
- 2023
- Full Text
- View/download PDF
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