Search

Your search keyword '"Heinicke N"' showing total 19 results
Start Over Author "Heinicke N"
19 results on '"Heinicke N"'

1. Poster display II clinical general

Author

Gurgenyan, S. V. Svetlana, Vatinyan, S. K. H., Nikogosyan, K. G., Edilyan, L. B., Chobanyan, B. G., Lacourcière, Y., Marcel Dumont, M., Lefebvre, J., Poirier, L., Côté, C., Peix, A. Amalia, Alonso, O., Chae, I. H., Chung, J. K., Gutierrez, C., Kropp, J., Onsel, C., Silvasi, I., Llerena, L., Padhy, A. K., Garcia-Barreto, D., Trapaga, A., Asen, L., Infante, O., Ponce, F., Cabrera, L. O., Valiente, J., Tornes, F., Guerrero, I., Zayas, R., ones, M. A. Quin, Castro, J., Fayad, Y., Carrillo, R., Paz, A. De, Mehlsen, J. Jesper, Hædersdal, C., Daou, D. Doumit, Benada, A., Lebtahi, R., Idy-Peretti, I., Guludec, D. Le, Coaguila, C., Vilain, D., Leenhardt, A., Heinicke, N. Norbert, Benesch, B., Kaiser, T., Seegmüller, M., Schönberger, J., Eilles, C., Riegger, G. A. J., Holmer, S., Luchner, A., Kouris, N. T. Nikos, Kontogianni, D. D., Goranitou, G. S., Sifaki, M. D., Kalkandi, E. M., Grassos, H. E., Papoulia, E., Babalis, D. K., Moralidis, E. Efstratios, Spyridonidis, T., Arsos, G., Karakatsanis, K., Karatzas, N., Parameswaran, R. V. Ramanathapuram, Sundaram, P. S. Palaniswamy Shanmuga, Padma, S., Haridas, K. K., Zachariah, M., Kumar, S., Feola, M. Mauro, Leonardi, G., Peano, S., Bianchi, A., Dutto, P., Guala, E., Biggi, A., Uslenghi, E., Filardi, P. Pasquale Perrone, Pace, L., Dellegrottaglie, S., Corrado, L., Cafiero, M., Camerino, R., Maglione, A., Polimeno, M., Zarrilli, A., Chiariello, M., Giorgetti, A. Assuero, Gimelli, A., Marini, C., Schluter, M., Kusch, A., D’Aragona, I., Marzullo, P., Gimelli, A. Alessia, Stanislao, M., Zanco, P., Inglese, E., Bertelli, P., Valle, G., Tassone, F., Pepino, R., Francini, A., Garrone, O., Occelli, M., Merlano, M., Florimonte, L. Luigia, Pagani, L., Piatti, L., Butti, I., Maffioli, L. S., Casorelli, E., Dottore, F. Del, Gentili, G., Agostini, M., Pieri, P. L. Pierluigi, Milan, E., Giubbini, R. Raffaele, Mazzanti, M. Marco, Serenelli, M., Perna, G. P., Ferro, A., Duilio, C., Santomauro, M., Salvatore, M., Cuocolo, A. Alberto, Bertagna, F., Bosio, G., Terzi, A., Paghera, B., Kaneta, T. Tomohiro, Otani, H., Hakamatsuka, T., Fukuda, H., Nakazato, R. Ryo, Moroi, M., Kunimasa, T., Furuhashi, T., Sugi, K., Yasuhi, W. Watanabe, Akihiro, S., Yukawa, A., Ryu, K., Kimio, T., Yasuhiko, T., Nariaki, E., Yasunori, W., Akashi, Y. J. Yoshihiro, Musha, H., Kida, K., Itoh, K., Inoue, K., Kawasaki, K., Hashimoto, N., Nakazawa, K., Miyake, F., Fukuzawa, S. Shigeru, Ozawa, S., Inagaki, M., Sugioka, J., Okino, S., Matsuo, S. Shinro, Matsumoto, T., Nakae, I., Masuda, D., Horie, M., Mori, Y. Yoshitomo, Takahashi, K., Masai, M., Kawasaki, D., Kanemori, T., Okuda, S., Tanabe, K., Ohyanagi, M., Takahashi, K. Keiko, Masai, M., Mori, Y., Tanabe, K., OKuda, S., Toyama, T. Takuji, Hoshizaki, H., Seki, R., Isobe, N., Kawaguchi, R., Oshima, S., Taniguchi, K., Nakagawa, K. Keiichi, Sekine, T., Yamazaki, M., Komuro, I., Kim, K. M. Kyeong Min, Teramoto, N., Jino, H., Ohta, Y., Watabe, H., Hayashi, T., Iida, H., Nishimura, T. Tohru, Nagae, A., Morishima, K., Shigeyama, T., Shimoyama, K., Yoshino, H., Kawai, Y. Yuko, Jeong, S. Y., Lee, J. Jae-Tae, Seo, J. H., Bae, J. H., Ahn, B. C., Chae, S. C., Lee, K. B., Cho, I. Ihnho, Chun, K., Won, K., Lee, H., Hong, G., Park, J., Shin, D., Kim, Y., Shim, B., Pavlovic, J. Maksimovic, Peovska, I. Irena, Vavlukis, M., Gorceva, D. Pop, Majstorov, V., Alexanderson, E. Erick, Meave, A., Ricalde, A., Teresinska, A. Anna, Sliwinski, M., Konieczna, S., Szymanska, M., Hendzel, P., Juraszynski, Z., Debski, A., Szumilak, B., Kostkiewicz, M. Magdalena, Wilkolek, P., Pasowicz, M., Klimeczek, P., Pieniazek, P., Przewlocki, T., Pieculewicz, M., Tracz, W., Szot, W., Trebacz, J., Zmudka, K., Podolec, P., Dziuk, M. Miroslaw, Kazmierczak, A., Kot, E., Pietrzykowski, J., Cholewa, M., Coutinho, M. C. Maria Azevedo, Correia, M. J., Cantinho, G., Conceição, I., Bernardes, A., Silva, A., Gaspar, F., Cunha, J. A. Correia da, Lourenço, C. Cândida, Roque, C., Ferrer-Antunes, A., Ferreira, M., Providência, L. A., Lima, J., Abreu, A. Ana, Castillejos, L., Henriksson, I., Oliveira, L., Rosário, L., Geão, A., Pereira, E., Colarinha, P., Romero-Farina, G., Candell-Riera, J., Aguadé-Bruix, S. Santiago, Leon, G. De, Caresia, A. P., Mila-Lopez, M., Garcia-Alonso, C., Pifarre-Montaner, P., Negre-Buso, M., Castell-Conesa, J., Mestre-Fusco, A., Porta-Biosca, F., Aguadé-Bruix, S. Santiago, Muxi, A. Africa, Paredes, P., Ortin, J., Duch, J., Diaz-Infante, E., Fuertes, S., Orus, J., Mont, L. L., Pons, F., Pollack, C., Hellermann, J. P., Namdar, M., Siegrist, P. T. Patrick, Koepfli, P., Bartenstein, N., Schurr, U., Jenni, R., Kaufmann, P. A., Hassad, R. Rim, Hamami, H., Sellem, A., Brahim, H. Ben, Caglar, M. Meltem, Mahmoudian, B., Aytemir, K., Kahraman, S., Arýcý, M., Kabakcý, G., Karabulut, E., Akincioglu, C. Cigdem, Berman, D. S., Nishina, H., Hayes, S. W., Kavanagh, P. B., Friedman, J. D., Slomka, P. J., Germano, G., Entok, E. Emre, Cavusoglu, Y., Vardareli, E., Timuralp, B., Cheetham, A., Naylor, V., Ghiotto, F., McGhie, J., Al-Housni, M. B., Kelion, A. D. Andrew, Hutchings, F., Hinton-Taylor, S., Birkbeck, P., Thatikonda, S., Feldkamp, M., Rosamond, T. Thomas, Raza, M., Panjrath, G. S. Gurusher, Haider, A., Jain, D., Yang, A., Schumacher, R., Reynolds, J., Clark, E., Speiser, D., Schindel, M., Hackney, T., Vacek, J., Jindal, V. Vikas, Dim, U. Uzodinma, Hamburg, L. M., Mouradian, V., Nichols, K. J., Akinboboye, O. O., Snyder, K., Polepalle, D., DePuey, G. Gordon, Khattak, H., Friedman, M., Thompson, L., Thompson, R. C. Randall, McGhie, A. I., Moser, K., O’Keefe, J. H., Fritsch, N., Bateman, T. M., Mut, F., Vidal, I., Rener, A., Nuñez, M., Alvarez, B., and Beretta, M. Mario

Published
2005
Full Text
View/download PDF

3. Poster display II clinical general

Author

Gurgenyan, S., Vatinyan, S., Nikogosyan, K., Edilyan, L., Chobanyan, B., Lacourcière, Y., Marcel Dumont, M., Lefebvre, J., Poirier, L., Côté, C., Peix, A., Alonso, O., Chae, I., Chung, J., Gutierrez, C., Kropp, J., Onsel, C., Silvasi, I., Llerena, L., Padhy, A., Garcia-Barreto, D., Trapaga, A., Asen, L., Infante, O., Ponce, F., Cabrera, L., Valiente, J., Tornes, F., Guerrero, I., Zayas, R., ones, M., Castro, J., Fayad, Y., Carrillo, R., Paz, A., Mehlsen, J., Hædersdal, C., Daou, D., Benada, A., Lebtahi, R., Idy-Peretti, I., Guludec, D., Coaguila, C., Vilain, D., Leenhardt, A., Heinicke, N., Benesch, B., Kaiser, T., Seegmüller, M., Schönberger, J., Eilles, C., Riegger, G., Holmer, S., Luchner, A., Kouris, N., Kontogianni, D., Goranitou, G., Sifaki, M., Kalkandi, E., Grassos, H., Papoulia, E., Babalis, D., Moralidis, E., Spyridonidis, T., Arsos, G., Karakatsanis, K., Karatzas, N., Parameswaran, R., Sundaram, P., Padma, S., Haridas, K., Zachariah, M., Kumar, S., Feola, M., Leonardi, G., Peano, S., Bianchi, A., Dutto, P., Guala, E., Biggi, A., Uslenghi, E., Filardi, P., Pace, L., Dellegrottaglie, S., Corrado, L., Cafiero, M., Camerino, R., Maglione, A., Polimeno, M., Zarrilli, A., Chiariello, M., Giorgetti, A., Gimelli, A., Marini, C., Schluter, M., Kusch, A., D'Aragona, I., Marzullo, P., Stanislao, M., Zanco, P., Inglese, E., Bertelli, P., Valle, G., Tassone, F., Pepino, R., Francini, A., Garrone, O., Occelli, M., Merlano, M., Florimonte, L., Pagani, L., Piatti, L., Butti, I., Maffioli, L., Casorelli, E., Dottore, F., Gentili, G., Agostini, M., Pieri, P., Milan, E., Giubbini, R., Mazzanti, M., Serenelli, M., Perna, G., Ferro, A., Duilio, C., Santomauro, M., Salvatore, M., Cuocolo, A., Bertagna, F., Bosio, G., Terzi, A., Paghera, B., Kaneta, T., Otani, H., Hakamatsuka, T., Fukuda, H., Nakazato, R., Moroi, M., Kunimasa, T., Furuhashi, T., Sugi, K., Yasuhi, W., Akihiro, S., Yukawa, A., Ryu, K., Kimio, T., Yasuhiko, T., Nariaki, E., Yasunori, W., Akashi, Y., Musha, H., Kida, K., Itoh, K., Inoue, K., Kawasaki, K., Hashimoto, N., Nakazawa, K., Miyake, F., Fukuzawa, S., Ozawa, S., Inagaki, M., Sugioka, J., Okino, S., Matsuo, S., Matsumoto, T., Nakae, I., Masuda, D., Horie, M., Mori, Y., Takahashi, K., Masai, M., Kawasaki, D., Kanemori, T., Okuda, S., Tanabe, K., Ohyanagi, M., OKuda, S., Toyama, T., Hoshizaki, H., Seki, R., Isobe, N., Kawaguchi, R., Oshima, S., Taniguchi, K., Nakagawa, K., Sekine, T., Yamazaki, M., Komuro, I., Kim, K., Teramoto, N., Jino, H., Ohta, Y., Watabe, H., Hayashi, T., Iida, H., Nishimura, T., Nagae, A., Morishima, K., Shigeyama, T., Shimoyama, K., Yoshino, H., Kawai, Y., Jeong, S., Lee, J., Seo, J., Bae, J., Ahn, B., Chae, S., Lee, K., Cho, I., Chun, K., Won, K., Lee, H., Hong, G., Park, J., Shin, D., Kim, Y., Shim, B., Pavlovic, J., Peovska, I., Vavlukis, M., Gorceva, D., Majstorov, V., Alexanderson, E., Meave, A., Ricalde, A., Teresinska, A., Sliwinski, M., Konieczna, S., Szymanska, M., Hendzel, P., Juraszynski, Z., Debski, A., Szumilak, B., Kostkiewicz, M., Wilkolek, P., Pasowicz, M., Klimeczek, P., Pieniazek, P., Przewlocki, T., Pieculewicz, M., Tracz, W., Szot, W., Trebacz, J., Zmudka, K., Podolec, P., Dziuk, M., Kazmierczak, A., Kot, E., Pietrzykowski, J., Cholewa, M., Coutinho, M., Correia, M., Cantinho, G., Conceição, I., Bernardes, A., Silva, A., Gaspar, F., Cunha, J., Lourenço, C., Roque, C., Ferrer-Antunes, A., Ferreira, M., Providência, L., Lima, J., Abreu, A., Castillejos, L., Henriksson, I., Oliveira, L., Rosário, L., Geão, A., Pereira, E., Colarinha, P., Romero-Farina, G., Candell-Riera, J., Aguadé-Bruix, S., Leon, G., Caresia, A., Mila-Lopez, M., Garcia-Alonso, C., Pifarre-Montaner, P., Negre-Buso, M., Castell-Conesa, J., Mestre-Fusco, A., Porta-Biosca, F., Muxi, A., Paredes, P., Ortin, J., Duch, J., Diaz-Infante, E., Fuertes, S., Orus, J., Mont, L., Pons, F., Pollack, C., Hellermann, J., Namdar, M., Siegrist, P., Koepfli, P., Bartenstein, N., Schurr, U., Jenni, R., Kaufmann, P., Hassad, R., Hamami, H., Sellem, A., Brahim, H., Caglar, M., Mahmoudian, B., Aytemir, K., Kahraman, S., Arýcý, M., Kabakcý, G., Karabulut, E., Akincioglu, C., Berman, D., Nishina, H., Hayes, S., Kavanagh, P., Friedman, J., Slomka, P., Germano, G., Entok, E., Cavusoglu, Y., Vardareli, E., Timuralp, B., Cheetham, A., Naylor, V., Ghiotto, F., McGhie, J., Al-Housni, M., Kelion, A., Hutchings, F., Hinton-Taylor, S., Birkbeck, P., Thatikonda, S., Feldkamp, M., Rosamond, T., Raza, M., Panjrath, G., Haider, A., Jain, D., Yang, A., Schumacher, R., Reynolds, J., Clark, E., Speiser, D., Schindel, M., Hackney, T., Vacek, J., Jindal, V., Dim, U., Hamburg, L., Mouradian, V., Nichols, K., Akinboboye, O., Snyder, K., Polepalle, D., DePuey, G., Khattak, H., Friedman, M., Thompson, L., Thompson, R., McGhie, A., Moser, K., O'Keefe, J., Fritsch, N., Bateman, T., Mut, F., Vidal, I., Rener, A., Nuñez, M., Alvarez, B., and Beretta, M.

Published
2018

9. A new land cover map of central Africa derived from multi-resolution, multi-temporal AVHRR data.

Author

Heinicke, N. T. Laporte S. J. Goetz C. O. Justice M.

Subjects
*RADIOMETERS, *MAPS
Abstract

We describe a new map of the central Africa region that was derived from National Oceanic and Atmospheric Administration Advanced Very High Resolution Radiometer (NOAA AVHRR) observations using a fusion of Local Area Coverage (LAC, 1 km), Global Area Coverage (GAC, 8 km), and ancillary information. The land cover map, produced for the Central Africa Regional Program for the Environment (CARPE), offers a synoptic view of the extent of central African dense humid forests, at relatively fine spatial resolution. Land cover types include dense humid forest, disturbed or degraded forest and various savanna classes. Ancillary information includes political and park boundaries, settlements, rivers and roads. Map validation was performed using a combination of field visits and finer resolution imagery (Landsat Multi-Spectral Scanner (MSS)). Forest cover type mapping errors were at most 20 per cent. The resulting map is useful for addressing a number of resource management issues, a few of which are examined. [ABSTRACT FROM AUTHOR]

Published
1998
Full Text
View/download PDF

10. Poster display II clinical general

Author

Gurgenyan, S., Vatinyan, S., Nikogosyan, K., Edilyan, L., Chobanyan, B., Lacourcière, Y., Marcel Dumont, M., Lefebvre, J., Poirier, L., Côté, C., Peix, A., Alonso, O., Chae, I., Chung, J., Gutierrez, C., Kropp, J., Onsel, C., Silvasi, I., Llerena, L., Padhy, A., Garcia-Barreto, D., Trapaga, A., Asen, L., Infante, O., Ponce, F., Cabrera, L., Valiente, J., Tornes, F., Guerrero, I., Zayas, R., ones, M., Castro, J., Fayad, Y., Carrillo, R., Paz, A., Mehlsen, J., Hædersdal, C., Daou, D., Benada, A., Lebtahi, R., Idy-Peretti, I., Guludec, D., Coaguila, C., Vilain, D., Leenhardt, A., Heinicke, N., Benesch, B., Kaiser, T., Seegmüller, M., Schönberger, J., Eilles, C., Riegger, G., Holmer, S., Luchner, A., Kouris, N., Kontogianni, D., Goranitou, G., Sifaki, M., Kalkandi, E., Grassos, H., Papoulia, E., Babalis, D., Moralidis, E., Spyridonidis, T., Arsos, G., Karakatsanis, K., Karatzas, N., Parameswaran, R., Sundaram, P., Padma, S., Haridas, K., Zachariah, M., Kumar, S., Feola, M., Leonardi, G., Peano, S., Bianchi, A., Dutto, P., Guala, E., Biggi, A., Uslenghi, E., Filardi, P., Pace, L., Dellegrottaglie, S., Corrado, L., Cafiero, M., Camerino, R., Maglione, A., Polimeno, M., Zarrilli, A., Chiariello, M., Giorgetti, A., Gimelli, A., Marini, C., Schluter, M., Kusch, A., D'Aragona, I., Marzullo, P., Stanislao, M., Zanco, P., Inglese, E., Bertelli, P., Valle, G., Tassone, F., Pepino, R., Francini, A., Garrone, O., Occelli, M., Merlano, M., Florimonte, L., Pagani, L., Piatti, L., Butti, I., Maffioli, L., Casorelli, E., Dottore, F., Gentili, G., Agostini, M., Pieri, P., Milan, E., Giubbini, R., Mazzanti, M., Serenelli, M., Perna, G., Ferro, A., Duilio, C., Santomauro, M., Salvatore, M., Cuocolo, A., Bertagna, F., Bosio, G., Terzi, A., Paghera, B., Kaneta, T., Otani, H., Hakamatsuka, T., Fukuda, H., Nakazato, R., Moroi, M., Kunimasa, T., Furuhashi, T., Sugi, K., Yasuhi, W., Akihiro, S., Yukawa, A., Ryu, K., Kimio, T., Yasuhiko, T., Nariaki, E., Yasunori, W., Akashi, Y., Musha, H., Kida, K., Itoh, K., Inoue, K., Kawasaki, K., Hashimoto, N., Nakazawa, K., Miyake, F., Fukuzawa, S., Ozawa, S., Inagaki, M., Sugioka, J., Okino, S., Matsuo, S., Matsumoto, T., Nakae, I., Masuda, D., Horie, M., Mori, Y., Takahashi, K., Masai, M., Kawasaki, D., Kanemori, T., Okuda, S., Tanabe, K., Ohyanagi, M., OKuda, S., Toyama, T., Hoshizaki, H., Seki, R., Isobe, N., Kawaguchi, R., Oshima, S., Taniguchi, K., Nakagawa, K., Sekine, T., Yamazaki, M., Komuro, I., Kim, K., Teramoto, N., Jino, H., Ohta, Y., Watabe, H., Hayashi, T., Iida, H., Nishimura, T., Nagae, A., Morishima, K., Shigeyama, T., Shimoyama, K., Yoshino, H., Kawai, Y., Jeong, S., Lee, J., Seo, J., Bae, J., Ahn, B., Chae, S., Lee, K., Cho, I., Chun, K., Won, K., Lee, H., Hong, G., Park, J., Shin, D., Kim, Y., Shim, B., Pavlovic, J., Peovska, I., Vavlukis, M., Gorceva, D., Majstorov, V., Alexanderson, E., Meave, A., Ricalde, A., Teresinska, A., Sliwinski, M., Konieczna, S., Szymanska, M., Hendzel, P., Juraszynski, Z., Debski, A., Szumilak, B., Kostkiewicz, M., Wilkolek, P., Pasowicz, M., Klimeczek, P., Pieniazek, P., Przewlocki, T., Pieculewicz, M., Tracz, W., Szot, W., Trebacz, J., Zmudka, K., Podolec, P., Dziuk, M., Kazmierczak, A., Kot, E., Pietrzykowski, J., Cholewa, M., Coutinho, M., Correia, M., Cantinho, G., Conceição, I., Bernardes, A., Silva, A., Gaspar, F., Cunha, J., Lourenço, C., Roque, C., Ferrer-Antunes, A., Ferreira, M., Providência, L., Lima, J., Abreu, A., Castillejos, L., Henriksson, I., Oliveira, L., Rosário, L., Geão, A., Pereira, E., Colarinha, P., Romero-Farina, G., Candell-Riera, J., Aguadé-Bruix, S., Leon, G., Caresia, A., Mila-Lopez, M., Garcia-Alonso, C., Pifarre-Montaner, P., Negre-Buso, M., Castell-Conesa, J., Mestre-Fusco, A., Porta-Biosca, F., Muxi, A., Paredes, P., Ortin, J., Duch, J., Diaz-Infante, E., Fuertes, S., Orus, J., Mont, L., Pons, F., Pollack, C., Hellermann, J., Namdar, M., Siegrist, P., Koepfli, P., Bartenstein, N., Schurr, U., Jenni, R., Kaufmann, P., Hassad, R., Hamami, H., Sellem, A., Brahim, H., Caglar, M., Mahmoudian, B., Aytemir, K., Kahraman, S., Arýcý, M., Kabakcý, G., Karabulut, E., Akincioglu, C., Berman, D., Nishina, H., Hayes, S., Kavanagh, P., Friedman, J., Slomka, P., Germano, G., Entok, E., Cavusoglu, Y., Vardareli, E., Timuralp, B., Cheetham, A., Naylor, V., Ghiotto, F., McGhie, J., Al-Housni, M., Kelion, A., Hutchings, F., Hinton-Taylor, S., Birkbeck, P., Thatikonda, S., Feldkamp, M., Rosamond, T., Raza, M., Panjrath, G., Haider, A., Jain, D., Yang, A., Schumacher, R., Reynolds, J., Clark, E., Speiser, D., Schindel, M., Hackney, T., Vacek, J., Jindal, V., Dim, U., Hamburg, L., Mouradian, V., Nichols, K., Akinboboye, O., Snyder, K., Polepalle, D., DePuey, G., Khattak, H., Friedman, M., Thompson, L., Thompson, R., McGhie, A., Moser, K., O'Keefe, J., Fritsch, N., Bateman, T., Mut, F., Vidal, I., Rener, A., Nuñez, M., Alvarez, B., Beretta, M., Gurgenyan, S., Vatinyan, S., Nikogosyan, K., Edilyan, L., Chobanyan, B., Lacourcière, Y., Marcel Dumont, M., Lefebvre, J., Poirier, L., Côté, C., Peix, A., Alonso, O., Chae, I., Chung, J., Gutierrez, C., Kropp, J., Onsel, C., Silvasi, I., Llerena, L., Padhy, A., Garcia-Barreto, D., Trapaga, A., Asen, L., Infante, O., Ponce, F., Cabrera, L., Valiente, J., Tornes, F., Guerrero, I., Zayas, R., ones, M., Castro, J., Fayad, Y., Carrillo, R., Paz, A., Mehlsen, J., Hædersdal, C., Daou, D., Benada, A., Lebtahi, R., Idy-Peretti, I., Guludec, D., Coaguila, C., Vilain, D., Leenhardt, A., Heinicke, N., Benesch, B., Kaiser, T., Seegmüller, M., Schönberger, J., Eilles, C., Riegger, G., Holmer, S., Luchner, A., Kouris, N., Kontogianni, D., Goranitou, G., Sifaki, M., Kalkandi, E., Grassos, H., Papoulia, E., Babalis, D., Moralidis, E., Spyridonidis, T., Arsos, G., Karakatsanis, K., Karatzas, N., Parameswaran, R., Sundaram, P., Padma, S., Haridas, K., Zachariah, M., Kumar, S., Feola, M., Leonardi, G., Peano, S., Bianchi, A., Dutto, P., Guala, E., Biggi, A., Uslenghi, E., Filardi, P., Pace, L., Dellegrottaglie, S., Corrado, L., Cafiero, M., Camerino, R., Maglione, A., Polimeno, M., Zarrilli, A., Chiariello, M., Giorgetti, A., Gimelli, A., Marini, C., Schluter, M., Kusch, A., D'Aragona, I., Marzullo, P., Stanislao, M., Zanco, P., Inglese, E., Bertelli, P., Valle, G., Tassone, F., Pepino, R., Francini, A., Garrone, O., Occelli, M., Merlano, M., Florimonte, L., Pagani, L., Piatti, L., Butti, I., Maffioli, L., Casorelli, E., Dottore, F., Gentili, G., Agostini, M., Pieri, P., Milan, E., Giubbini, R., Mazzanti, M., Serenelli, M., Perna, G., Ferro, A., Duilio, C., Santomauro, M., Salvatore, M., Cuocolo, A., Bertagna, F., Bosio, G., Terzi, A., Paghera, B., Kaneta, T., Otani, H., Hakamatsuka, T., Fukuda, H., Nakazato, R., Moroi, M., Kunimasa, T., Furuhashi, T., Sugi, K., Yasuhi, W., Akihiro, S., Yukawa, A., Ryu, K., Kimio, T., Yasuhiko, T., Nariaki, E., Yasunori, W., Akashi, Y., Musha, H., Kida, K., Itoh, K., Inoue, K., Kawasaki, K., Hashimoto, N., Nakazawa, K., Miyake, F., Fukuzawa, S., Ozawa, S., Inagaki, M., Sugioka, J., Okino, S., Matsuo, S., Matsumoto, T., Nakae, I., Masuda, D., Horie, M., Mori, Y., Takahashi, K., Masai, M., Kawasaki, D., Kanemori, T., Okuda, S., Tanabe, K., Ohyanagi, M., OKuda, S., Toyama, T., Hoshizaki, H., Seki, R., Isobe, N., Kawaguchi, R., Oshima, S., Taniguchi, K., Nakagawa, K., Sekine, T., Yamazaki, M., Komuro, I., Kim, K., Teramoto, N., Jino, H., Ohta, Y., Watabe, H., Hayashi, T., Iida, H., Nishimura, T., Nagae, A., Morishima, K., Shigeyama, T., Shimoyama, K., Yoshino, H., Kawai, Y., Jeong, S., Lee, J., Seo, J., Bae, J., Ahn, B., Chae, S., Lee, K., Cho, I., Chun, K., Won, K., Lee, H., Hong, G., Park, J., Shin, D., Kim, Y., Shim, B., Pavlovic, J., Peovska, I., Vavlukis, M., Gorceva, D., Majstorov, V., Alexanderson, E., Meave, A., Ricalde, A., Teresinska, A., Sliwinski, M., Konieczna, S., Szymanska, M., Hendzel, P., Juraszynski, Z., Debski, A., Szumilak, B., Kostkiewicz, M., Wilkolek, P., Pasowicz, M., Klimeczek, P., Pieniazek, P., Przewlocki, T., Pieculewicz, M., Tracz, W., Szot, W., Trebacz, J., Zmudka, K., Podolec, P., Dziuk, M., Kazmierczak, A., Kot, E., Pietrzykowski, J., Cholewa, M., Coutinho, M., Correia, M., Cantinho, G., Conceição, I., Bernardes, A., Silva, A., Gaspar, F., Cunha, J., Lourenço, C., Roque, C., Ferrer-Antunes, A., Ferreira, M., Providência, L., Lima, J., Abreu, A., Castillejos, L., Henriksson, I., Oliveira, L., Rosário, L., Geão, A., Pereira, E., Colarinha, P., Romero-Farina, G., Candell-Riera, J., Aguadé-Bruix, S., Leon, G., Caresia, A., Mila-Lopez, M., Garcia-Alonso, C., Pifarre-Montaner, P., Negre-Buso, M., Castell-Conesa, J., Mestre-Fusco, A., Porta-Biosca, F., Muxi, A., Paredes, P., Ortin, J., Duch, J., Diaz-Infante, E., Fuertes, S., Orus, J., Mont, L., Pons, F., Pollack, C., Hellermann, J., Namdar, M., Siegrist, P., Koepfli, P., Bartenstein, N., Schurr, U., Jenni, R., Kaufmann, P., Hassad, R., Hamami, H., Sellem, A., Brahim, H., Caglar, M., Mahmoudian, B., Aytemir, K., Kahraman, S., Arýcý, M., Kabakcý, G., Karabulut, E., Akincioglu, C., Berman, D., Nishina, H., Hayes, S., Kavanagh, P., Friedman, J., Slomka, P., Germano, G., Entok, E., Cavusoglu, Y., Vardareli, E., Timuralp, B., Cheetham, A., Naylor, V., Ghiotto, F., McGhie, J., Al-Housni, M., Kelion, A., Hutchings, F., Hinton-Taylor, S., Birkbeck, P., Thatikonda, S., Feldkamp, M., Rosamond, T., Raza, M., Panjrath, G., Haider, A., Jain, D., Yang, A., Schumacher, R., Reynolds, J., Clark, E., Speiser, D., Schindel, M., Hackney, T., Vacek, J., Jindal, V., Dim, U., Hamburg, L., Mouradian, V., Nichols, K., Akinboboye, O., Snyder, K., Polepalle, D., DePuey, G., Khattak, H., Friedman, M., Thompson, L., Thompson, R., McGhie, A., Moser, K., O'Keefe, J., Fritsch, N., Bateman, T., Mut, F., Vidal, I., Rener, A., Nuñez, M., Alvarez, B., and Beretta, M.

11. Time course of eosinophilic myocarditis visualized by CMR

Author

Feuerbach Stefan, Heinicke Norbert, Poschenrieder Florian, Buchner Stefan, Djavidani Behrus, Debl Kurt, Riegger Günter, and Luchner Andreas

Subjects
Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Abstract We report the diagnostic potential of cardiovascular magnetic resonance (CMR) to visualize the time course of eosinophilic myocarditis upon successful treatment. A 50-year-old man was admitted with a progressive heart failure. Endomyocardial biopsies were taken from the left ventricle because of a white blood cell count of 17000/mm3 with 41% eosinophils. Histological evaluation revealed endomyocardial eosinophilic infiltration and areas of myocyte necrosis. The patient was diagnosed with hypereosinophilic myocarditis due to idiopathic hypereosinophilic syndrome. CMR-studies at presentation and a follow-up study 3 weeks later showed diffuse subendocardial LGE in the whole left ventricle. Upon treatment with steroids, CMR-studies revealed marked reduction of subendocardial LGE after 3 months in parallel with further clinical improvement. This case therefore highlights the clinical importance of CMR to visualize the extent of endomyocardial involvement in the diagnosis and treatment of eosinophilic myocarditis.

Published
2008
Full Text
View/download PDF

12. Dual platelet inhibition in cases of severe retrobulbar hemorrhage following retrobulbar and peribulbar anesthesia.

Author

Huebert I, Heinicke N, Kook D, Boost KA, Miller CV, Mayer WJ, Haritoglou C, Kampik A, Gandorfer A, Hintschich C, and Wolf A

Subjects
Aged, Anticoagulants therapeutic use, Arterial Occlusive Diseases drug therapy, Aspirin adverse effects, Aspirin therapeutic use, Cardiac Surgical Procedures, Cardiovascular Diseases drug therapy, Clopidogrel, Drug Combinations, Female, Humans, Male, Platelet Aggregation Inhibitors therapeutic use, Retrobulbar Hemorrhage diagnosis, Retrobulbar Hemorrhage surgery, Retrospective Studies, Risk Factors, Ticlopidine adverse effects, Ticlopidine analogs & derivatives, Ticlopidine therapeutic use, Warfarin adverse effects, Warfarin therapeutic use, Anesthesia, Local methods, Anticoagulants adverse effects, Lens Implantation, Intraocular, Phacoemulsification, Platelet Aggregation Inhibitors adverse effects, Retrobulbar Hemorrhage chemically induced
Abstract

Purpose: To evaluate the prevalence of dual platelet inhibition in cases of severe retrobulbar hemorrhage following retrobulbar and peribulbar anesthesia., Setting: Department of Ophthalmology, Ludwig-Maximilans Universität, München, Germany., Design: Retrospective study., Methods: Two groups of patients were screened retrospectively over a 5-year period for the inclusion criterion of severe retrobulbar hematoma after retrobulbar or parabulbar injection. The first group consisted of emergency cases referred to the clinic. A second group of patients had received retrobulbar block at the hospital. All cases were collected and screened for the presence of antiplatelet therapy., Results: Among roughly 160 000 patient records screened, 3 patients with grade IV retrobulbar hematoma were identified. Two of these patients were taking dual antiplatelet medications and 2 were on anticoagulation therapy during the time of retrobulbar or peribulbar anesthesia. None of the cases showed single medication platelet inhibition. The visual acuity of all patients stayed low at the 6-month follow-up (1.2 logMAR in 1 patient and no light perception in 2 patients)., Conclusions: Retrobulbar hematoma is a rare but severe complication of retrobulbar anesthesia. With the high prevalence of dual platelet inhibition found in these cases, a prospective controlled trial seems unethical. In these high-risk patients, surgery should be performed under topical anesthesia if possible or general anesthesia if necessary., Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned., (Copyright © 2015. Published by Elsevier Inc.)

Published
2015
Full Text
View/download PDF

13. Comparison of PV signal quality using a novel circular mapping and ablation catheter versus a standard circular mapping catheter.

Author

von Bary C, Fredersdorf-Hahn S, Heinicke N, Jungbauer C, Schmid P, Riegger GA, and Weber S

Subjects
Aged, Body Surface Potential Mapping methods, Catheter Ablation methods, Catheters, Female, Follow-Up Studies, Humans, Imaging, Three-Dimensional, Intraoperative Care methods, Male, Middle Aged, Pulmonary Veins diagnostic imaging, Radiography, Risk Assessment, Tachycardia, Paroxysmal diagnosis, Tachycardia, Paroxysmal surgery, Treatment Outcome, Atrial Fibrillation diagnosis, Atrial Fibrillation surgery, Body Surface Potential Mapping instrumentation, Catheter Ablation instrumentation, Electrophysiologic Techniques, Cardiac methods, Pulmonary Veins surgery
Abstract

Purpose: Recently, new catheter technologies have been developed for atrial fibrillation (AF) ablation. We investigate the diagnostic accuracy of a circular mapping and pulmonary vein ablation catheter (PVAC) compared with a standard circular mapping catheter (Orbiter) and the influence of filter settings on signal quality., Methods: After reconstruction of the left atrium by three-dimensional atriography, baseline PV potentials (PVP) were recorded consecutively with PVAC and Orbiter in 20 patients with paroxysmal AF. PVPs were compared and attributed to predefined anatomical PV segments. Ablation was performed in 80 PVs using the PVAC. If isolation of the PVs was assumed, signal assessment of each PV was repeated with the Orbiter. If residual PV potentials could be uncovered, different filter settings were tested to improve mapping quality of the PVAC. Ablation was continued until complete PV isolation (PVI) was confirmed with the Orbiter., Results: Baseline mapping demonstrated a good correlation between the Orbiter and PVAC. Mapping accuracy using the PVAC for mapping and ablation was 94% (74 of 79 PVs). Additional mapping with the Orbiter improved the PV isolation rate to 99%. Adjustment of filter settings failed to improve quality of the PV signals compared with standard filter settings., Conclusions: Using the PVAC as a stand-alone strategy for mapping and ablation, one should be aware that in some cases, different signal morphology mimics PVI isolation. Adjustment of filter settings failed to improve signal quality. The use of an additional mapping catheter is recommended to become familiar with the particular signal morphology during the first PVAC cases or whenever there is a doubt about successful isolation of the pulmonary veins.

Published
2011
Full Text
View/download PDF

14. N-terminal pro-brain natriuretic peptide from fresh urine for the biochemical detection of heart failure and left ventricular dysfunction.

Author

Jungbauer CG, Buchner S, Birner C, Resch M, Heinicke N, Debl K, Buesing M, Biermeier D, Schmitz G, Riegger G, and Luchner A

Subjects
Biomarkers, Confidence Intervals, Feasibility Studies, Female, Fluid Therapy, Glomerular Filtration Rate, Heart Failure physiopathology, Heart Failure urine, Humans, Logistic Models, Male, Middle Aged, Natriuretic Peptide, Brain analysis, Odds Ratio, Peptide Fragments analysis, Predictive Value of Tests, ROC Curve, Sensitivity and Specificity, Severity of Illness Index, Statistics as Topic, Stroke Volume, Ventricular Dysfunction, Left physiopathology, Ventricular Dysfunction, Left urine, Ventricular Function, Left, Heart Failure diagnosis, Natriuretic Peptide, Brain urine, Peptide Fragments urine, Ventricular Dysfunction, Left diagnosis
Abstract

Aims: Plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) is a strong biochemical marker of heart failure and left ventricular dysfunction (LVD). Due to renal arterio-venous clearance of NT-proBNP and the correlation of plasma concentrations with renal function, we hypothesized that NT-proBNP may have potential as a urinary marker. The objective of this study was to assess urinary concentrations of NT-proBNP and to identify the predictive value of urinary NT-proBNP for detecting LVD and heart failure., Methods and Results: N-terminal pro-brain natriuretic peptide (Elecsys proBNP((R)), Roche) was assessed simultaneously in fresh spot urine and plasma from 191 individuals. In patients with heart failure (n = 149), urinary and plasma NT-proBNP concentrations were positively correlated (r = 0.79, P < 0.001), but urinary NT-proBNP was significantly lower than plasma NT-proBNP (42 +/- 25 vs. 1389 +/- 325 pg/mL, P < 0.001). Upon receiver operating curve analysis, urinary NT-proBNP detected LV dysfunction (ejection fraction <40%) with a sensitivity of 91% and a specificity of 98% at a cutpoint of 22 pg/mL [area under the curves (AUC) 0.98]. At the same cutpoint, symptomatic heart failure (NYHA-class > 2) was detected with a sensitivity of 97% and specificity of 98% (AUC 0.99) and clinical signs of fluid retention were detected with a sensitivity and specificity of 98% each (AUC 0.99)., Conclusion: N-terminal pro-brain natriuretic peptide concentrations were markedly lower in the urine than in the plasma. However, urinary NT-proBNP levels increased stepwise with the severity of heart failure and LVD, and therefore yielded satisfactory predictive values for the detection of significant LVD and symptomatic heart failure. Measurement of urinary NT-proBNP is a novel, promising, and simple method for the biochemical detection of heart failure.

Published
2010
Full Text
View/download PDF

15. Improvement of the cardiac marker N-terminal-pro brain natriuretic peptide through adjustment for renal function: a stratified multicenter trial.

Author

Luchner A, Weidemann A, Willenbrock R, Philipp S, Heinicke N, Rambausek M, Mehdorn U, Frankenberger B, Heid IM, Eckardt KU, and Holmer SR

Subjects
Adolescent, Adult, Aged, Biomarkers blood, Demography, Echocardiography, Glomerular Filtration Rate, Humans, Kidney Diseases physiopathology, Kidney Function Tests, Male, Middle Aged, Predictive Value of Tests, Regression Analysis, Ventricular Dysfunction, Left diagnosis, Ventricular Dysfunction, Left etiology, Kidney Diseases blood, Natriuretic Peptide, Brain blood, Peptide Fragments blood
Abstract

Background: N-terminal-pro brain natriuretic peptide (NT-proBNP) is a useful cardiac marker that is also influenced by renal dysfunction. It was our objective to assess the relationship between NT-proBNP concentrations in plasma and worsening renal function, and to attempt adjustment of NT-proBNP for renal dysfunction in a prospective, stratified multi-center study., Methods: We stratified 203 male patients according to their cardiac status and the estimated glomerular filtration rate (eGFR). Cardiac disease was assessed by medical history, physical examination and standardized echocardiography. Patients were stratified according to the following: absence of cardiac history and abnormalities (control, CTRL, n=66), cardiac history without left ventricular hypertrophy (LVH) or left ventricular systolic dysfunction (LVD) (history, n=30), LVH without systolic dysfunction (LVH, n=68), and LVD [ejection fraction (EF) <40%, LVD, n=39]. Renal disease was stratified according to the eGFR: 15-30 mL/min (n=52), 31-75 mL/min (n=99), and >75 mL/min (n=52)., Results: NT-proBNP was correlated with eGFR in the entire study population and for all levels of cardiac disease (all p<0.01). Regression analysis allowed adjustment of NT-proBNP for eGFR in a continuous manner, and this adjustment significantly improved the predictive value (receiver operating characteristic curve for symptomatic LVD from 0.80 to 0.86, p<0.01; sensitivity from 74% to 83% and specificity from 68% to 79%)., Conclusions: NT-proBNP correlates inversely and significantly with eGFR throughout all levels of cardiac strata. We propose for the first time a continuous adjustment algorithm which markedly improves the predictive values of NT-proBNP in male patients with impaired renal function.

Published
2010
Full Text
View/download PDF

16. Safe and rapid isolation of pulmonary veins using a novel circular ablation catheter and duty-cycled RF generator.

Author

Fredersdorf S, Weber S, Jilek C, Heinicke N, VON Bary C, Jungbauer C, Riegger GA, Hamer OW, and Jeron A

Subjects
Adult, Aged, Equipment Design, Equipment Failure Analysis, Female, Humans, Male, Middle Aged, Radio Waves, Atrial Fibrillation surgery, Catheter Ablation instrumentation, Heart Conduction System surgery, Pulmonary Veins surgery, Transducers
Abstract

Background: Ablation of atrial fibrillation (AF) has been one of the most difficult and time-consuming electrophysiological procedures. Due to the rapidly increasing demand for ablation procedures, technical advances would be helpful to reduce complexity and procedure time in AF ablation. Therefore, we investigated the feasibility of a single-catheter technique for pulmonary vein (PV) isolation utilizing a decapolar catheter combined with a duty-cycled, unipolar-bipolar radiofrequency (RF) generator., Methods: AF mapping and ablation was performed in 21 consecutive patients (mean age 59 +/- 12 years, 9 males) with paroxysmal AF (n = 17) and persistent AF (n = 4). The ablation catheter was forwarded to the LA via single-transseptal puncture. All electrodes were energized in 2 to 5 applications per vein, followed by segmental RF applications, as needed, to achieve electrical isolation. To assess left atrial anatomy for purposes of catheter manipulation, and later evaluate the possibility of asymptomatic PV-stenosis, CT or MR imaging was performed both prior to ablation and at 6-month follow-up., Results: Isolation could be achieved in 85/86 veins (99%). Procedure time for ablation was 81 +/- 13 minutes, and fluoroscopy time was 30 +/- 11 minutes. There were no procedural complications. Success rate at 6 months was 86% (18/21). MR or CT imaging excluded asymptomatic PV-stenosis., Conclusion: Mapping and ablation of PVs can be performed in a safe and efficient manner using a single-catheter technique, with short procedure times and minimal learning curve. Thus, this system may be of high interest not only for high volume but all centers performing AF ablation.

Published
2009
Full Text
View/download PDF

17. Unicuspid aortic valve disease: a magnetic resonance imaging study.

Author

Debl K, Djavidani B, Buchner S, Poschenrieder F, Heinicke N, Schmid C, Kobuch R, Feuerbach S, Riegger G, and Luchner A

Subjects
Adult, Aortic Valve physiopathology, Aortic Valve Stenosis diagnostic imaging, Aortic Valve Stenosis surgery, Blood Pressure, Diastole, Female, Heart Valve Diseases diagnostic imaging, Heart Valve Diseases surgery, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Mitral Valve pathology, Radiography, Retrospective Studies, Rheumatic Heart Disease diagnostic imaging, Rheumatic Heart Disease surgery, Systole, Aortic Valve abnormalities, Aortic Valve Stenosis pathology, Heart Valve Diseases pathology, Rheumatic Heart Disease pathology
Abstract

Purpose: Congenitally malformed aortic valves are a common finding in adults with aortic valve disease. Most of these patients have bicuspid aortic valve disease. Unicuspid aortic valve disease (UAV) is rare. The aim of our study was to describe valve morphology and the dimensions of the proximal aorta in a cohort of 12 patients with UAV in comparison to tricuspid aortic valve disease (TAV) using magnetic resonance imaging (MRI)., Materials and Methods/results: MRI studies were performed on a 1.5 T scanner in a total of 288 consecutive patients with aortic valve disease. 12 aortic valves were retrospectively classified as UAV. Annulus areas and dimensions of the thoracic aorta were retrospectively compared to a cohort of 103 patients with TAV. In UAV, valve morphology was unicuspid unicommissural with a posterior commissure in all patients. Mean annulus areas and mean diameters of the ascending aorta were significantly greater in UAV compared to TAV (12.6 +/- 4.7 cm (2) vs. 8.7 +/- 2.3 cm (2), p < 0.01 and 4.6 +/- 0.7 cm vs. 3.6 +/- 0.5 cm, p < 0.0001, respectively), while no differences were observed in the mean diameters of the aortic arch (2.3 +/- 0.6 cm vs. 2.3 +/- 0.4 cm, p = 0.69). The diameters of the descending aorta were slightly smaller in UAV compared to TAV (2.2 +/- 0.5 cm vs. 2.6 +/- 0.3 cm, p < 0.05)., Conclusion: In UAV, visualization of valve morphology by MRI is possible with good image quality. Valve morphology was classified as unicuspid unicommissural in all UAV patients. Dilatation of the proximal aorta > 4.5 cm is a frequent finding in UAV. Additional assessment of aortic dimensions is therefore recommended in patients with UAV.

Published
2008
Full Text
View/download PDF

18. Time course of eosinophilic myocarditis visualized by CMR.

Author

Debl K, Djavidani B, Buchner S, Poschenrieder F, Heinicke N, Feuerbach S, Riegger G, and Luchner A

Subjects
Biopsy, Needle, Glucocorticoids therapeutic use, Humans, Male, Middle Aged, Myocarditis drug therapy, Myocarditis etiology, Time Factors, Eosinophilia, Magnetic Resonance Imaging methods, Myocarditis diagnosis
Abstract

We report the diagnostic potential of cardiovascular magnetic resonance (CMR) to visualize the time course of eosinophilic myocarditis upon successful treatment. A 50-year-old man was admitted with a progressive heart failure. Endomyocardial biopsies were taken from the left ventricle because of a white blood cell count of 17000/mm3 with 41% eosinophils. Histological evaluation revealed endomyocardial eosinophilic infiltration and areas of myocyte necrosis. The patient was diagnosed with hypereosinophilic myocarditis due to idiopathic hypereosinophilic syndrome. CMR-studies at presentation and a follow-up study 3 weeks later showed diffuse subendocardial LGE in the whole left ventricle. Upon treatment with steroids, CMR-studies revealed marked reduction of subendocardial LGE after 3 months in parallel with further clinical improvement. This case therefore highlights the clinical importance of CMR to visualize the extent of endomyocardial involvement in the diagnosis and treatment of eosinophilic myocarditis.

Published
2008
Full Text
View/download PDF

19. Mechanisms of regional wall motion abnormalities in contrast-enhanced dobutamine stress echocardiography.

Author

Heinicke N, Benesch B, Kaiser T, Debl K, Segmüller M, Schönberger J, Marienhagen J, Eilles C, Riegger GA, Holmer S, and Luchner A

Subjects
Cardiotonic Agents, Chi-Square Distribution, Coronary Angiography, Coronary Artery Disease diagnostic imaging, Dobutamine, Female, Humans, Male, Middle Aged, Predictive Value of Tests, Radiopharmaceuticals, Sensitivity and Specificity, Technetium Tc 99m Sestamibi, Tomography, Emission-Computed, Single-Photon, Coronary Artery Disease physiopathology
Abstract

Background: In the diagnosis of coronary artery disease (CAD) with Dobutamine Stress Echocardiography (DSE), regional wall motion abnormalities (RWMA) are assumed to indicate a perfusion deficit., Methods and Results: For a more particular examination of RWMAs, we compared simultaneous echo-contrast (Optisone)-enhanced DSE (0-40 microg/kg Dobutamine, 16-segment- model) and MiBi-SPECT in a prospective double-blinded study design in 69 non-selected consecutive patients (44 male, 25 female, age 64+/-12 years). Additionally, all patients were examined by coronary-angiography. The prevalence of significant CAD (stenosis >50% lumen diameter) was 52%. DSE had a sensitivity of 78% and a specificity of 66% for the detection of significant CAD with a positive and negative predictive value of 72 and 73%, respectively. Among 28 patients with significant CAD and positive DSE study (true positive), 78% displayed a corresponding perfusion deficit in MiBi-SPECT. Among 11 patients with a positive DSE study but no current significant coronary stenosis (false positive), 82% showed stress-induced RWMAs in the inferior/posterior region, 73% displayed left ventricular hypertrophy, 54% resting-ECG abnormalities and 45% resting-RWMA (3 previous MI, 2 previous CABG surgery). Among 8 patients with negative DSE study but significant coronary stenosis (false negative), 75% had a stenosis of the LCX, 63% displayed resting- WMA, 63% displayed left bundle branch block or ST-segment depression, 50% displayed only peripheral coronary stenosis, and DSE visualization was suboptimal in 38%., Conclusion: This prospective study in non-selected patients shows that the majority of RWMAs in DSE are matched to a perfusion deficit detectable by nuclear imaging. Nevertheless, pre-existing cardiac abnormalities may also lead to stress-induced RWMA not associated with a perfusion deficit or mask a perfusion deficit upon DSE. Particularly in patients with LV hypertrophy, resting-RWMA, bundle branch block or ST segment depression, the predictive value of DSE may, therefore, be limited.

Published
2006
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results