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29 results on '"Heimes, Britta"'

1. Initiale Diagnostik und Indikationsstellung zur Anti-Vascular-Endothelial Growth-Factor-Therapie bei Netzhauterkrankungen: Vergleich der Befundung durch Studienarzt versus Reading Center (ORCA/OCEAN-Studie)

Author

Brinkmann, Christian K., Chang, Petrus, Schick, Tina, Heimes, Britta, Vögeler, Jessica, Haegele, Birgit, Kirchhof, Bernd, Holz, Frank G., Pauleikhoff, Daniel, Ziemssen, Focke, Liakopoulos, Sandra, Spital, Georg, and Schmitz-Valckenberg, Steffen

Published
2019
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3. Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study

Author

von der Burchard, Claus, primary, Sudkamp, Helge, additional, Tode, Jan, additional, Ehlken, Cristoph, additional, Purtskhvanidze, Konstantine, additional, Moltmann, Moritz, additional, Heimes, Britta, additional, Koch, Peter, additional, Münst, Michael, additional, vom Endt, Malte, additional, Kepp, Timo, additional, Theisen-Kunde, Dirk, additional, König, Inke, additional, Hüttmann, Gereon, additional, and Roider, Johann, additional

Published
2022
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11. Initiale Diagnostik und Indikationsstellung zur Anti-Vascular-Endothelial Growth-Factor-Therapie bei Netzhauterkrankungen

Author

Brinkmann, Christian K., primary, Chang, Petrus, additional, Schick, Tina, additional, Heimes, Britta, additional, Vögeler, Jessica, additional, Haegele, Birgit, additional, Kirchhof, Bernd, additional, Holz, Frank G., additional, Pauleikhoff, Daniel, additional, Ziemssen, Focke, additional, Liakopoulos, Sandra, additional, Spital, Georg, additional, and Schmitz-Valckenberg, Steffen, additional

Published
2018
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12. Möglichkeiten der 2D und 3D Bildverarbeitung bei der OCT-Angiographie

Author

Heimes, Britta, Rothaus, K., Ziegler, M., Farecki, M., Gutfleisch, M., Spital, G., Lommatzsch, A., and Pauleikhoff, D.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die OCT-Angiographie (OCTA) stellt ein nicht-invasives Verfahren zur Darstellung der Perfusion der Netzhaut dar. In den Standardansichten der Geräte werden vorgefertigte Schichten dargestellt, welche abhängig von einer korrekten Segmentierung sind. Besonders in Anwesenheit von[zum vollständigen Text gelangen Sie über die oben angegebene URL], 29. Jahrestagung der Retinologischen Gesellschaft

Published
2016

13. Pitfalls in Retinal OCT Imaging

Author

Schmitz-Valckenberg, Steffen, primary, Brinkmann, Christian Karl, additional, Heimes, Britta, additional, Liakopoulos, Sandra, additional, Spital, Georg, additional, Holz, Frank Gerhard, additional, and Fleckenstein, Monika, additional

Published
2017
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14. OCEAN: Erste multizentrische Real-Life Daten der Indikation DMÖ (P1)

Author

Heimes, Britta, Ziemssen, Focke, Schmitz-Valckenberg, Steffen, Liakopoulos, Sandra, Spital, Georg, Wiedon, Annette, and Holz, Frank G.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Zielsetzung: Die nicht-interventionelle OCEAN-Studie beobachtet den Einsatz der Lucentis-Therapie im klinischen Alltag in allen zugelassenen Indikationen. OCEAN bietet damit erstmals multizentrische Real-Life Daten über die Lucentis-Behandlung von Patienten mit einer Visusbeeinträchtigung [for full text, please go to the a.m. URL], 27. Internationaler Kongress der Deutschen Ophthalmochirurgen

Published
2014
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18. Choroidal thickness under Anti-VEGF-therapy in exudative AMD

Author

Heimes, Britta, Ziegler, M., Book, B., Breiter, D., Lommatzsch, A., Gutfleisch, M., Dietzel, M., Spital, G., Zeimer, M., and Pauleikhoff, D.

Subjects
genetic structures, ddc: 610, sense organs, 610 Medical sciences, Medicine, eye diseases
Abstract

Background: Intravitreal anti-VEGF therapy represents the standard treatment of exudative AMD. So far the course of choroidal thickness during Anti-VEGF-therapy in AMD has not been reported extensively. Methods: We observed 44 eyes with a mean follow up of 94 weeks under treatment with intravitreal[for full text, please go to the a.m. URL], 26. Jahrestagung der Retinologischen Gesellschaft

Published
2013
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19. Assoziation von OCT Veränderungen mit der Sehschärfe im Verlauf >1 Jahr unter Anti-VEGF-Therapie bei exsudativer AMD

Author

Heimes, Britta, Ziegler, M., Book, B., Lommatzsch, A., Dietzel, M., Gutfleisch, M., Zeimer, M., Spital, G., and Pauleikhoff, D.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die Standardtherapie der exsudativen AMD ist die intravitreale Behandlung mit Anti-VEGF, welche jedoch individuell unterschiedliche Ansprechverhalten hervorruft. Darum analysierten wir initiale, morphologische Veränderungen im Spectral-Domain-OCT und korrelierten sie zum Visus. [for full text, please go to the a.m. URL], 175. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte

Published
2013

29. [Baseline diagnostics and initial treatment decision for anti-vascular endothelial growth factor treatment in retinal diseases : Comparison between results by study physician and reading centers (ORCA/OCEAN study)].

Author

Brinkmann CK, Chang P, Schick T, Heimes B, Vögeler J, Haegele B, Kirchhof B, Holz FG, Pauleikhoff D, Ziemssen F, Liakopoulos S, Spital G, and Schmitz-Valckenberg S

Subjects
Angiogenesis Inhibitors, Humans, Intravitreal Injections, Ranibizumab, Reading, Tomography, Optical Coherence, Vascular Endothelial Growth Factor A, Retinal Diseases
Abstract

Background: The ORCA module of the non-interventional OCEAN study investigated the use of retinal imaging diagnostics in the clinical treatment of patients undergoing vascular endothelial growth factor (VEGF) inhibitor treatment as part of routine clinical care. This article analyzes the agreement between the diagnosis documented by the treating ophthalmologist and the evaluation of reading centers at baseline as well as the effect on the response to treatment during the course., Methods: A total of 396 patients (age 75.4 years) were enrolled in which ranibizumab treatment was indicated by the treating ophthalmologist due to either diabetic macular edema (DME), neovascular age-related macular degeneration (nvAMD) or retinal venous occlusion (RVO). Over a period of 24 months, patient and examination data, treatments and interpretation of retinal imaging data by the treating ophthalmologist were systematically recorded. Furthermore, retinal imaging data were also evaluated by three reading centers., Results: In 338 out of 396 (85.4%) study eyes, the baseline diagnosis of the treating ophthalmologist was confirmed by the reading centers (DME 87.5%, nvAMD 82.3%, RVO 94.9%). In 17 of the remaining 58 eyes with a discrepant diagnosis, there was at least a consensus with respect to the indications for VEGF inhibitor therapy. The differential diagnoses included a variety of different retinal diseases. During follow-up of up to 3 months, eyes with a consistent diagnosis showed a clear increase in visual acuity (6.4 versus 2.7 letters, p = 0.05) and greater decrease in central retinal thickness (-112.3 versus -24.4 μm, p < 0.0001)., Discussion: The initial treatment decision for anti-VEGF therapy with consideration of the differential diagnoses can be challenging. Accurate evaluation of the clinical and imaging findings along with appropriate expertise appear to be important. The observation of superior initial response in eyes with a consensus of the diagnosis at baseline underlines the relevance of an adequate initial assessment for a successful treatment outcome.

Published
2019
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