Search

Tetraspanin membrane proteins form physical complexes with signaling molecules and have been suggested to influence the signaling events of associated molecules. Of the tetraspanin proteins, CD82 has been shown to promote homotypic cell-cell adhesion, which partially accounts for its role in suppressing cancer invasion and metastasis. We found here that CD82-induced cell-cell adhesion is attributed to increased E-cadherin expression through CD82-mediated downregulation of the E-cadherin repressor Snail. The Snail repression by CD82 resulted from the reduced binding of the Sp1 transcription factor to the Snail gene promoter. Notably, high CD82 expression did not allow the fibronectin matrix to induce Sp1 phosphorylation, implicating CD82 inhibition of the fibronectin-integrin signaling-dependent Sp1 activation. Meanwhile, E-cadherin upregulated by CD82 pulled β-catenin up to the membrane region, and consequently reduced the amount of cytoplasmic β-catenin that was able to move into to the nucleus. The Wnt signal-induced nuclear translocation of β-catenin was also inhibited by the CD82 function of upregulating E-cadherin. Overall, high CD82 expression was likely to suppress fibronectin adhesion-induced Sp1 activation signaling for Snail expression, resulting in continuous E-cadherin expression, which contributed not only to the maintenance of strong cell-cell adhesion but also to the blockage of nuclear β-catenin signaling.

Networked multi-agent dynamic system (NMDS) exhibits emergent swarming behavior by using local control laws based on spatial information from the nearby environment and adjacent agents. One of the challenges in NMDS is the lack of appropriate methods for operators to interact with a large group of agents. Studies on human–agent interaction have mainly focused on the direct influence on the behavior of the multi-agents, but it is not feasible for a large-scale system in an error-prone environment. In this letter, a robust method for indirect configuration propagation by a human operator is proposed to influence the swarming behavior of NMDS in a decentralized manner. In addition, an estimation method is proposed for the operator to observe the system state, which helps the operator provide an optimal input to the NMDS at the appropriate time. Finally, we demonstrate the superiority of the proposed method through theoretical analysis and simulation results.

In city, identification for 3 phase-4 wires power distribution lines is difficult due to compound installation of overhead and underground lines, transposition, bad view caused by trees or big buildings. It is necessary that the correct and fast identification method is required for load balancing among distribution lines. Tracing off-line method with high power impulse signal injection has been used recently. Our proposed method uses to identify live lines with very small power high frequency signal injection based on data communication technology. Two end communication terminals are required to be synchronized between them for determination on electrically same phases. Challenging issue is to achieve synchronization without GPS providing synchronizing time. A novel power transformer and phase identification system is designed and implemented. The system consists of a transmitter and a receiver with power-line communication module. Some experiments are conducted to verify the theoretical concepts in a big commercial building.

// Jaeseob Lee 1, * , Hee-Jung Byun 1, * , Moon-Sung Lee 2 , Young-June Jin 1 , Dooil Jeoung 3 , Young-Myeong Kim 4 , Hansoo Lee 1, 2 1 Department of Biological Sciences, College of Natural Sciences, Kangwon National University, Chunchon, Kangwon-do 200-701, Republic of Korea 2 BIT Medical Convergence Graduate Program, Kangwon National University, Chunchon, Kangwon-do 200-701, Republic of Korea 3 Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chunchon, Kangwon-do 200-701, Republic of Korea 4 Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chunchon, Kangwon-do 200-701, Republic of Korea * These authors have contributed equally to this work Correspondence to: Hansoo Lee, email: hslee@kangwon.ac.kr Keywords: CD82, EMT, fibronectin matrix, integrin signaling, cancer invasion Received: July 22, 2016 Accepted: November 14, 2016 Published: December 01, 2016 ABSTRACT The transmembrane protein CD82/KAI1 suppresses the metastatic potential of various cancer cell types. Moreover, decrease or loss of CD82 expression is closely associated with malignancy and poor prognosis in many human cancers including prostate cancer. Despite intense scrutiny, the mechanisms underlying the metastasis-suppressing role of CD82 are still not fully understood. Here, we found that a fibronectin matrix induced mesenchymal phenotypes in human prostate cancer cells with no or low CD82 expression levels. However, high CD82 expression rendered prostate cancer cells to have intensified epithelial characteristics upon fibronectin engagement, along with decreased cell motility and invasiveness. The CD82 function of inhibiting fibronectin-induced epithelial-to-mesenchymal transition (EMT) was dependent not only on CD82 interactions with fibronectin-binding α 3 β 1 /α 5 β 1 integrins but also on the integrin-mediated intracellular signaling events. Notably, CD82 attenuated the FAK-Src and ILK pathways downstream of the fibronectin-receptor integrins. Immunofluorescence staining of human prostate cancer tissue specimens illustrated a negative association of CD82 with EMT-related gene expression as well as prostate malignancy. Altogether, these results suggest that CD82 suppresses EMT in prostate cancer cells adhered to the fibronectin matrix by repressing adhesion signaling through lateral interactions with the associated α 3 β 1 and α 5 β 1 integrins, leading to reduced cell migration and invasive capacities.

In this paper, the method that allows for the combined control scheme of the imitation and autonomous control for a humanoid robot via Internet is presented. Our approach does not use any prior analytical or mathematical robot modeling (e.g. forward or inverse kinematics). All the way from the human operator with encoders to the humanoid joints, many server motors and encoders are connected with single communication path for the imitation control. The key concept for autonomous control is added to let the robot stabilize by utilization of tracing the CoP (center of pressure) and controlling the ankle of the robot’s support foot prior to impact in real time. Thread programming technology is introduced to enhance the control and operation speed up, and explained how to operate joints. The experimental results demonstrate that the humanoid robot can successfully imitate the motions of the operator and can walk stably by both utilizing the CoP and controlling the robot’s ankles.

무선센서 네트워크(WSNs)는 일반적으로 수많은 센서노드들이 배치되어 데이터를 전송하며, 불필요한 데이터 전송으로 인해 에너지 낭비를 초래한다. 기존의 연구들은 주로 에너지 소모문제를 해결하는데 집중되었다. 하지만 실시간으로 정보전송이 필요한 어플리케이션에 대해서는 지연 보장 역시 고려되어야 한다. 본 논문은 생체시스템을 모방하여 무선센서망에서 에너지의 소모와 연시간을 줄이기 위한 BISA(Bio-inspired Scheduling Algorithm)를 제안한다. BISA는 에너지 효율성이 높은 라우팅경로를 탐색하고 다중채널을 이용해 데이터 전송경로를 다중화함으로써 데이터 전송을 위한 에너지소모와 지연시간을 최소화한다. 실험결과를 통해 제안한 알고리즘의 기존방식 보다 적은 에너지를 사용하며 동시에 요구지연 시간을 보장함을 확인한다.

In this paper a method that allows for the control of a humanoid robot with foot sensors through an imitation control approach is presented. Our approach does not use any prior analytical or mathematical robot modeling (e.g. forward or inverse kinematics). The key concept is to trace the CoP (center of pressure) as fast as possible and to control the ankle of the robot’s support foot prior to impact. The experimental results demonstrate that a humanoid robot can successfully imitate the motions of the operator and can walk stably by utilizing both the CoP and controlling the robot’s ankle.

The purpose of this paper is to show that a biped robot can walk by an imitation control. It proposes architecture and system for real-time imitation control of a biped robot. Using this method, the operator can interact with the robot to walk. The operator produces trajectory data necessary to start, stop, walk and redirect the robot. We have to send control commands or new angular position values for to the robot as fast as possible. To get intuition how fast the robot should be controlled, its falling time which as the primary time question is discussed. An inverted pendulum calculation example and the real robot fall down experiment were compared in this paper.

To realizing the imitation control of the biped humanoid robot, synchronous question is the core problem. Falling time of the robot and reflecting time of the operator both are the components which to real-time control of the robot. If the robot can walk well in limited time, between the two parts time questions, communication time need us to analyze. Based on the imitation control structure of our robot control system, characters of control model and communication system were studied and conclusions show that synchronous control for a robot by a human is difficult to realize and some other stable control methods need to add in the research.

Power grids are large complicated networks in use around. An absolute phase value for a particular unknown-phase line at a local site should be identified for the operation and management of a 3-phase distribution network. The phase shift for a specific point in the line, as compared with a phase reference point at a substation, must be within a range of ± 60 o for correct identification. However, the phase shift at a particular point can fluctuate depending on the line constants, transformer wiring method, line length, and line amperage, etc. Conducted in this study is a theoretical formulation for the determination of phase at a specific point in the line, Simulink modeling, and analysis for a distribution network. In particular, through evaluating the effects of unbalanced current loads, the limitations of the present phase identification methods are described.

The energy consumption problem should be taken into consideration in wireless sensor network. Many studies have been proposed to address the energy consumption and delay problem. In this paper, we propose BISA(Bio-inspired Scheduling Algorithm) to reduce the energy consumption and delay in wireless sensor networks based on biological system. BISA investigates energy-efficient routing path and minimizes the energy consumption and delay using multi-channel for data transmission by multiplexing data transmission path. Through simulation, we confirm that the proposed scheme guarantees the efficient energy consumption and delay requirement.

In this paper, the subband nonlinear adaptive Volterra filters are introduced and its analysis are presented. From the eigenvalue analysis of the input correlation matrix, we show that the proposed subband adaptive Volterra filter has superior convergence performance as compared to the conventional one, which shows that the it can be useful for the recently proposed subband nonlinear adaptive echo canceller. Also, the optimum filter in each subband are introduced and verified from the computer simulations.

In this paper, we propose a joint control scheme to maximize network lifetime in wireless sensor networks with joint contention and sleep control. For the contention resolution of sensor nodes in the network, we consider the p-persistent contention protocol. Also, the sleep control is introduced with the probability of turning off the transceiver of a sensor node. Using the probabilities of contention and sleep, we formulate the network lifetime maximization problem to satisfy the throughput requirement and each link's signal to noise interference ratio (SINR) requirement. Finally, we demonstrate that the proposed scheme improves the lifetime of wireless sensor networks compared to the existing schemes.

Foot type robot is a popular research field and quadruped robot has vast application. This paper proposes and sets up a new kind of structure for quadruped robot based on Scilab after studying the quadruped animal’s leg structure. Then establishes reference frames by using D-H method and solves the positive and negative kinematic problems of the quadruped robot. Finally, using the open software Scilab which has been used in the study of mobile robot for the first time to simulate and analyze the kinematics characteristics of the robot.

Due to increased multiculturalism in the US and abroad, there is a need for increased understanding of the different ways in which parenting stress is related to child problems across cultures. In the present study, we investigated (a) differences in reported parenting stress and childhood problem behaviors across a Korean (n = 71) and US (n = 71) sample, as well as (b) differences in the ways in which parenting stress and childhood problems were related across Korean and US children based on mothers' reports. Results revealed that Korean mothers reported significantly higher parenting stress yet significantly lower childhood problem behaviors compared to US mothers. In addition, mother-based reports of child problems were significantly associated with parenting stress in the US sample, but not in the Korean sample. Clinical implications and culturally-relevant issues relevant to these findings are addressed, including a potential under-reporting bias of child problems among Asian parents.

In this paper, the necessity for the identification of the absolute phase value is introduced and analyzed for a particular conductor line of a 3-phase type distribution network and the recent methods are also introduced. For the determination of the exact phase value for a specific point in the line, as compared with the phase reference point, the measured phase value must be within a range of . However, the phase of a particular point can fluctuate depending on the line constant, transformer wiring method, line length, line amperage, etc. A theoretical formulation such as Simulink modeling and analysis for a distribution network are conducted for the identification of phase at a specific point in the line. In particular, through evaluating the effects of unbalanced current loads at the time of determination of the phase value, the limitations of the present method for the determination of phases is described.

This paper proposes a scheme for distributed load balancing in mobile communication networks based on supervisory control framework. Using load information exchanged with neighboring cells, the "supervisors" that reside in the base stations distribute load among cells by controlling handover parameters in a distributed manner. The supervisors are designed so that the load difference among neighboring cells are kept under a pre-defined value. Results from systematic analysis and simulation indicate that our scheme effectively balances traffic load among cells and reduces call blocking rate of the overloaded cells.

KAI1/CD82, a tetraspanin membrane protein functions as a metastasis suppressor in many types of human cancers and has been shown to regulate cell adhesion properties. In the present study, we investigated the underlying mechanism of KAI1/CD82-mediated changes in cell adhesion to the extracellular matrix using human prostate cancer cells. We found that high KAI1/CD82 expression attenuated short-term cell adhesion to uncoated- or fibronectin-coated plates. Moreover, high KAI1/CD82 expression generated an extracellular environment unfavorable for cell adhesion as compared to low KAI1/CD82 expression, suggesting KAI1/CD82-dependent regulation of extracellular matrix (ECM) molecule(s) expression and/or secretion. Among ECM components examined, fibronectin exhibited decreased expression and secretion in high KAI1/CD82-expressing cells. Furthermore, high KAI1/CD82 expression interfered with the activation of β (1) integrin at the cell surface while total β (1) integrin levels remained unchanged, concomitant with reduced formation of focal adhesion complex and decreased bundling of actin filaments. Finally, high KAI1/CD82 expression significantly retarded cell motility in a scratch wound assay. Taken together, our results strongly suggest that KAI1/CD82 attenuates the activation of β (1) integrin, and thereby down-regulates outside-in signaling of β (1) integrin, leading to the reduction of focal adhesion formation and fibronectin expression/secretion, which subsequently interferes with cell adhesion properties and motility.

The activity of matrix metalloproteinases (MMPs), which selectively degrades the extracellular matrix (ECM), is critical in angiogenesis. Conversely, changes in ECM composition/structure alter the expression and activity of MMPs in various cell types. In the present study, we examined whether changes in ECM composition affect MMPs expression/activity of endothelial cells and thereby alter the surrounding ECM structure. Among the ECM molecules examined, fibronectin (FN) and vitronectin (VN) increased the expression and activity of MMP-9 in human umbilical vein endothelial cells (HUVECs). Both α(5)β(1) and α(v)β(3) integrins were involved in FN-induced MMP-9 expression. Also, FN-induced MMP-9 expression was found to be mediated by AP-1 transcription factors, including c-Jun, JunB, and JunD. Inhibitors or siRNAs specific to AP-1 activating signal transducers, including FAK-Src, PI3K/Akt, ERK, and JNK, abolished both FN-induced AP-1 activation and MMP-9 expression. VN-induced AP-1 activation and MMP-9 expression were also mediated by these AP-1 activating signal transducers in addition to p38 MAPK. Moreover, treatment with FN or VN resulted in increased degradation of collagen on HUVEC culture plates. Taken together, our data suggest that both fibronectin and vitronectin induce MMP-9 expression via the AP-1-activating signaling pathways in endothelial cells, and thereby stimulate degradation of surrounding collagen, leading to alterations in ECM structure and potentially the promotion of angiogenesis.

This paper proposes a systematic approach to the rate-based feedback control based on the supervisory control framework for discrete event systems. We design the supervisor to achieve the desired behavior for TCP wireless networks. From the analysis and simulation results, it is shown that the controlled networks guarantee the fair sharing of the available bandwidth and avoid the packet loss caused by the buffer overflow of TCP wireless networks.

In this paper, we propose an algorithm to improve TCP performance over wireless links. TCP is known to have poor performance over wireless links because TCP has no mechanism to differentiate congestion loss from wireless loss, and treats all losses as congestive. We present a simple method to determine the cause of packet loss using the successive ECN. In addition, we present an algorithm to control the congestion window size based on the estimated queue state in order to guarantee the fairness and high link utilization.

In addition to high bit error rates, large and sudden variations in delay often occur in wireless cellular networks. The delay can be several times the typical round-trip time, which can cause the spurious timeout. In this letter, we propose a new window control algorithm to improve TCP performance in wireless cellular networks with large delay variation and high bit error rates. Simulation results illustrate that our proposal improves the performance of TCP in terms of fairness and link utilization.

The authors investigated the subjective cognitive dysfunction associated with drug-induced parkinsonism (DIP) among 58 stabilized schizophrenic outpatients. Subjective cognitive dysfunction was comprehensively assessed using the Frankfurt Complaint Questionnaire (FCQ). Multivariate analysis revealed that the DIP group scored significantly higher on the total FCQ score than the non-DIP group. In phenomenological subscale scores, the DIP group had significantly higher scores on “deterioration of discrimination”, “psychomotor disorder”, and “perceptual disorder” than the non-DIP group. These results suggest that DIP is significantly associated with subjective cognitive-perceptual dysfunction, reflecting the complex nature of DIP that includes motor and cognitive aspects.

In this letter, we suggest APMAC (Adaptive Power Control MAC) for wireless ad hoc networks. APMAC is based on the single channel environment and improves the throughput and the energy efficiency simultaneously. Furthermore, the APMAC prevents the unfair channel starvation among the transmission pairs. We verify the performance of the APMAC through simulations.

Summary Background and objective: Antipsychotic-induced akathisia leads to poor compliance with medication and is still a source of concern in the treatment with antipsychotic drugs. Regarding clinical characteristics, the distinguishing features of akathisia in comparison with other extrapyramidal syndromes are prominent subjective symptoms. The purpose of the present study was to examine the subjective cognitive dysfunction associated with antipsychotic-induced akathisia. Methods: Sixty-seven outpatients with schizophrenia receiving stable doses of risperidone or haloperidol were evaluated for akathisia and other extrapyramidal side effects. Subjective cognitive dysfunction was comprehensively assessed using the Frankfurt Complaint Questionnaire (FCQ). The severity of subjective cognitive deficits was compared between the groups with and without akathisia using analysis of covariance with relevant variables as covariates. Results: The akathisia group (n = 25) scored significantly higher on the total FCQ score than the non-akathisia group (n = 42) (P

Power Line carrier communication is applied to identify cables in power distribution systems. Cable in distribution systems has only a limited ability to carry higher frequencies. To the top of that, transformers prevent propagating its higher frequency carrier signal. A new cable identification system is proposed to use its limited propagation characteristics. The cable identification system is designed and implemented based on a transmitter and a receiver with power line carrier communication. Some experiments are conducted to verify the theoretical concepts. Also some simulations are done to help and understand the concepts by using Simulink simulator.

Power-line communication technology is applied to identify cables in power distribution system. The application area of power-line communication will be extended in this paper. Power cable circuits have only a limited ability to carry higher frequencies. Also, transformers prevent propagating the higher frequency carrier signal. The proposed method uses its limited propagation ability to identify the cable. A new cable identification system is proposed and implemented. The system consists of a transmitter and a receiver with power- line communication module. Some experiments are conducted to verify the theoretical concepts.

IEEE 802.11 MAC is the most commonly used MAC layer protocol in multi-hop ad hoc networks. When the network load becomes heavy, the throughput performance of IEEE 802.11 MAC is decreased because of the high collision rates and the low spatial reuse of the channel. In this letter, we analyze the throughput of multi-hop ad hoc networks and propose a supervisory control framework to maximize the throughout.

The tetraspanin membrane protein CD151 has been suggested to regulate cancer invasion and metastasis by initiating signaling events. The CD151-mediated signaling pathways involved in this regulation remain to be revealed. In this study, we found that stable transfection of CD151 into MelJuSo human melanoma cells lacking CD151 expression significantly increased cell motility, matrix metalloproteinase-9 (MMP-9) expression, and invasiveness. The enhancement of cell motility and MMP-9 expression by CD151 overexpression was abrogated by inhibitors and small interfering RNAs targeted to focal adhesion kinase (FAK), Src, p38 MAPK, and JNK, suggesting an essential role of these signaling components in CD151 signaling pathways. Also, CD151-induced MMP-9 expression was shown to be mediated by c-Jun binding to AP-1 sites in the MMP-9 gene promoter, indicating AP-1 activation by CD151 signaling pathways. Meanwhile, CD151 was found to be associated with alpha(3)beta(1) and alpha(6)beta(1) integrins in MelJuSo cells, and activation of associated integrins was a prerequisite for CD151-stimulated MMP-9 expression and activation of FAK, Src, p38 MAPK, JNK, and c-Jun. Furthermore, CD151 on one cell was shown to bind to neighboring cells expressing CD151, suggesting that CD151 is a homophilic interacting protein. The homophilic interactions of CD151 increased motility and MMP-9 expression of CD151-transfected MelJuSo cells, along with FAK-, Src-, p38 MAPK-, and JNK-mediated activation of c-Jun in an adhesion-dependent manner. Furthermore, C8161 melanoma cells with endogenous CD151 were also shown to respond to homophilic CD151 interactions for the induction of adhesion-dependent activation of FAK, Src, and c-Jun. These results suggest that homophilic interactions of CD151 stimulate integrin-dependent signaling to c-Jun through FAK-Src-MAPKs pathways in human melanoma cells, leading to enhanced cell motility and MMP-9 expression.

In this letter, we suggest a rate-based supervisory congestion control scheme for the ad hoc networks that use TCP as the transport protocol. This scheme makes it possible for the TCP sender to distinguish the causes of packet loss. In addition, this scheme guarantees the fair sharing of the available bandwidth among the connections. We show the reliability of our scheme by using the supervisory control framework and simulations confirm the effectiveness of our scheme.

This paper describes a max-min fair rate allocation scheme in multicast networks based on the supervisory control framework for discrete event systems. Based on the discrete event model of multicast networks, we design a supervisor to guarantee the max-min fair allocation of bandwidth. Analysis and simulations are used to show that the controlled networks guarantee the max-min fair sharing with a low message exchange overhead and fast convergence time.

The metric properties of the Drug-Induced Extrapyramidal Symptoms Scale (DIEPSS) were examined in 182 subjects treated with antipsychotics. Inter-rater reliability, test-retest reliability, and concurrent validity with other rating scales for EPS were high. Four factors were identified and the optimal diagnostic cut-off scores were obtained. These results suggest that the DIEPSS is a reliable and valid multidimensional rating scale.

In this letter, we propose a scheme for the guaranteed end-to-end delay with the proportional fair scheduling in wireless networks. With the newly introduced delay parameter, we adjust the queue length of each link. Specifically, we formulate a new optimization problem which guarantees the average end-to-end delay of each flow in wireless networks. Through simulation, we show that network throughput is improved while guaranteeing the average end-to-end delay compared to the existing results.

Despite the importance of multiple tetraspanin proteins in cancer invasion and metastasis, little is known about the role and significance of tetraspanin CD81 in these processes. In the present study, we examined CD81 effects on melanoma cell invasiveness and metastasis. Transfection of CD81 into melanoma cells lacking endogenous CD81 expression significantly enhanced the migrating, invasive, and metastatic abilities of melanoma cells. Interestingly, membrane type 1 matrix metalloproteinase (MT1-MMP) expression was found in CD81-expressing melanoma cells but not in CD81-deficient cells. siRNA knockdown of CD81 in melanoma cells with endogenous CD81 demonstrated decreased MT1-MMP levels and cell motility. Notably, CD81-induced cell migration was abrogated by antibody blocking and siRNA knockdown of MT1-MMP, indicating that MT1-MMP is responsible for CD81-stimulated melanoma cell migration. Promoter analysis revealed an essential role of the Sp1 transcription factor in CD81-induced MT1-MMP transcription. We also demonstrate that the Sp1-activating Akt pathway is involved in adhesion-dependent CD81 signaling to induce MT1-MMP expression and cell motility. Importantly, human skin cancer tissue specimens displayed a positive correlation of CD81 with MT1-MMP expression levels and a close association of CD81 with malignant melanomas. Taken together, these results strongly suggest that CD81 stimulates melanoma cell motility by inducing MT1-MMP expression through the Akt-dependent Sp1 activation signaling pathway, leading to increased melanoma invasion and metastasis.

This paper presents a new humanoid robot control structure - Man-Function humanoid robot. The sensing devices worn on the human body, these devices will produce signals of joints’ change when people move. Computer of the control system receiving the signals and processing them, then issue control signals to the servos of the robot at the same time, control the robot’s behavior. For this reason, a control structure of human’s behavior to determine the robot’s behavior formed. The humanoid robot has 17 servos and two pressure sensors, the rotation of these servos’ steering gears lead to the robot’s behavior changes, and 12 servos corresponding to the human body sensing devices, other 5 servos used for the stability control of the robot combined with the pressure sensors. Based on this control structure, some pilot tests of the sensing device or servo have been done, the closed-loop position control mode has been chosen and the Kalman filter smoothing optimization method been used, the initial static walking control of the robot been realized. DOI: http://dx.doi.org/10.11591/telkomnika.v11i12.3891

We present a method to calssify electromyogram (EMG) signals which are utilized as control signals for a patient-responsive walker-supported system for paraplegics. Patterns of EMG signals for different walking motions are classified via adequate filtering, real EMG signal extraction, AR-modeling, and a modified self-organizing feature map (MSOFM). In particular, a data-reducing extraction algorithm is employed for real EMG signals. Moreover, MSOFM classifies and determines the results automatically using a fixed map. Finally, the experimental results are presented for validation.

Most of TCP schemes in wireless networks assume that the bandwidth of the bottleneck link remains constant over time. However, in wireless cellular networks, to effectively manage the limited resources, the bandwidth is controlled based on radio condition over time. Such varying bandwidth can cause the networks congestion or underutilization. In this letter, we propose a new window control algorithm to improve TCP performance in wireless cellular networks with variable bandwidth. Simulation results illustrate that our proposal improves the performance of TCP in terms of fairness and link utilization

This paper proposes a systematic approach to the rate-based feedback control based on the supervisory control framework for discrete event systems. Since communication networks can be represented as discrete event systems, we design the supervisor to generate the admissible behavior for TCP wireless networks. It is shown that the controlled networks guarantee the fair sharing of the available bandwidth and avoid the packet loss caused by the-buffer overflow of TCP wireless networks.