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Your search keyword '"Hedley, Helen"' showing total 5 results
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5 results on '"Hedley, Helen"'

1. Surgery versus cast immobilisation for adults with a bicortical fracture of the scaphoid waist (SWIFFT): a pragmatic, multicentre, open-label, randomised superiority trial

Author

Dias, Joseph J, Brealey, Stephen D, Fairhurst, Caroline, Amirfeyz, Rouin, Bhowal, Bhaskar, Blewitt, Neil, Brewster, Mark, Brown, Daniel, Choudhary, Surabhi, Coapes, Christopher, Cook, Liz, Costa, Matthew, Davis, Tim, Di Mascio, Livio, Giddins, Grey, Hedley, Helen, Hewitt, Catherine, Hinde, Sebastian, Hobby, Jonathan, Hodgson, Stephen, Jefferson, Laura, Jeyapalan, Kanagaratnam, Johnston, Phillip, Jones, Jonathon, Keding, Ada, Leighton, Paul, Logan, Andrew, Mason, Will, McAndrew, Andrew, McNab, Ian, Muir, Lindsay, Nicholl, James, Northgraves, Matthew, Palmer, Jared, Poulter, Rob, Rahimtoola, Zulfi, Rangan, Amar, Richards, Simon, Richardson, Gerry, Stuart, Paul, Taub, Nicholas, Tavakkolizadeh, Adel, Tew, Garry, Thompson, John, Torgerson, David, and Warwick, David

Published
2020
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2. Surgical fixation with K-wires versus casting in adults with fracture of distal radius: DRAFFT2 multicentre randomised clinical trial

Author

Costa, Matthew L, Achten, Juul, Ooms, Alexander, Png, May Ee, Cook, Jonathan A, Lamb, Sarah E, Hedley, Helen, Dias, Joseph, Dritsaki, Melina, Dakin, Helen, Jones, Jonathan, Mckee, Andrew, Smith, Kevin, Hamadto, Mohamed, Gwilym, Steve, Chesser, Tim, Candal-Couto, Jaime, Hing, Caroline, Giddin, David, Johnston, Phil, Ullah, Aamer, Williams, John, Eardley, Will, Srinivasan, Makaram, Sampalli, Sridharrao, Farrar, Mark, Roberts, Chris, Mohanty, Khitish, MacLeod, Iain, Sarda, Praveen, Elseehy, Amr, Rossiter, Nigel, Warwick, David, Peach, Chris, MacKay, David, Benson, Richard, Watts, Adam, Young, Jonathan, Shah, Feisal, Lipscombe, Stephen, Ng, Aaron, Charalambous, Bambos, Sheriden, Barnaby, Theivendran, Kanthan, Sanjay, Pulimamidi, Nanda, Rajesh, Bateman, Antony, Butler, Michael, Keast-Butler, Oliver, McAndrew, Andrew, Chevannes, Wystan, Kankanalu, Pradeep, Wijendra, Asanka, Fontalis, Andreas, Afifi, Hytham, Killen, Marie-Clare, Higgin, Ryan, Wignadasan, Warran, Wong, Ken, Gibson, Catherine, Beale, Harry, Jennings, Bob, Kennedy, James, Williamson, Mark, Rasidovic, Damir, Jenner, Lydia, Tadros, John Baha, Milner, Steve, Duncan, James, Kerr, Sally, Nordin, Louise, Weston, Matt, Payton, Olivia, Oni, Tofi, Zhao, Craig, Gill, Sukhdeep, Iqbal, Mohammad, Aneiba, Khaled, Pillai, Dilip, Hughes, Luke, Crosby, Jonathan, Whitehouse, Mike, Corbett, Thomas, Iqbal, Arshad, Buchan, Steph, Beddard, Laura, Vardhan, Venkat, Beamish, Becky, Jones, Matt, Holley, Jonathan, Morrell, Rebecca, Lerner, Robin, and Draper, Kylea

Subjects
Adult, Male, Wrist Joint, Adolescent, Research, General Medicine, Middle Aged, United Kingdom, Casts, Surgical, Young Adult, Treatment Outcome, Fracture Fixation, Humans, Female, Radius Fractures, Bone Wires
Abstract

Objective To assess wrist function, quality of life, and complications in adult patients with a dorsally displaced fracture of the distal radius, treated with either a moulded cast or surgical fixation with K-wires. Design Multicentre randomised clinical superiority trial, Setting 36 hospitals in the UK National Health Service (NHS). Participants 500 adults aged 16 or over with a dorsally displaced fracture of the distal radius, randomised after manipulation of their fracture (255 to moulded cast; 245 to surgical fixation). Interventions Manipulation and moulded cast was compared with manipulation and surgical fixation with K-wires plus cast. Details of the application of the cast and the insertion of the K-wires were at the discretion of the treating surgeon, according to their normal clinical practice. Main outcome measures The primary outcome measure was the Patient Rated Wrist Evaluation (PRWE) score at 12 months (five questions about pain and 10 about function and disability; overall score out of 100 (best score=0 and worst score=100)). Secondary outcomes were PRWE score at three and six months, quality of life, and complications, including the need for surgery due to loss of fracture position in the first six weeks. Results The mean age of participants was 60 years and 417 (83%) were women; 395 (79%) completed follow-up. No statistically significant difference in the PRWE score was seen at 12 months (cast group (n=200), mean 21.2 (SD 23.1); K-wire group (n=195), mean 20.7 (22.3); adjusted mean difference −0.34 (95% confidence interval −4.33 to 3.66), P=0.87). No difference was seen at earlier time points. In the cast group, 33 (13%) of participants needed surgical fixation for loss of fracture position in the first six weeks compared with one revision surgery in the K-wire group (odds ratio 0.02, 95% confidence interval 0.001 to 0.10). Conclusions Among patients with a dorsally displaced distal radius fracture that needed manipulation, surgical fixation with K-wires did not improve patients’ wrist function at 12 months compared with a cast. Trial registration ISRCTN registry ISRCTN11980540 .

Published
2022

3. Cost-utility analysis of surgical fixation with Kirschner wire versus casting after fracture of the distal radius

Author

Png, May Ee, Petrou, Stavros, Achten, Juul, Ooms, Alexander, Lamb, Sarah E., Hedley, Helen, Dias, Joseph, and Costa, Matthew L.

Abstract

AimsThe aim of this study was to compare the cost-effectiveness of surgical fixation with Kirschner (K-)wire ersus moulded casting after manipulation of a fracture of the distal radius in an operating theatre setting.MethodsAn economic evaluation was conducted based on data collected from the Distal Radius Acute Fracture Fixation Trial 2 (DRAFFT2) multicentre randomized controlled trial in the UK. Resource use was collected at three, six, and 12 months post-randomization using trial case report forms and participant-completed questionnaires. Cost-effectiveness was reported in terms of incremental cost per quality-adjusted life year (QALY) gained from an NHS and personal social services perspective. Sensitivity analyses were conducted to examine the robustness of cost-effectiveness estimates, and decision uncertainty was handled using confidence ellipses and cost-effectiveness acceptability curves.ResultsIn the base case analysis, surgical fixation with K-wire was more expensive (£29.65 (95% confidence interval (CI) -94.85 to 154.15)) and generated lower QALYs (0.007 (95% CI -0.03 to 0.016)) than moulded casting, but this difference was not statistically significant. The probability of K-wire being cost-effective at a £20,000 per QALY cost-effectiveness threshold was 24%. The cost-effectiveness results remained robust in the sensitivity analyses.ConclusionThe findings suggest that surgical fixation with K-wire is unlikely to be a cost-effective alternative to a moulded cast in adults, following manipulation of a fracture of the distal radius in a theatre setting.Cite this article: Bone Joint J2022;104-B(11):1225–1233.

Published
2022
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5. Surgical fixation with K-wires versus plaster casting in the treatment of dorsally displaced distal radius fractures: protocol for Distal Radius Acute Fracture Fixation Trial 2 (DRAFFT 2)

Author

Achten, Juul, primary, Sones, William, additional, Dias, Joseph, additional, Hedley, Helen, additional, Cook, Jonathan A, additional, Dritsaki, Melina, additional, Png, May Ee, additional, Gray, Alastair, additional, Lamb, Sarah E, additional, and Costa, Matthew L, additional

Published
2019
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