108 results on '"Heckl D"'
Search Results
2. A CRISPR-based platform to model AML progression using primary human cells
3. Upstream regulation of DLK1-DIO3 locus in hematopoiesis and pediatric leukemia
4. Identifying gene targets for drug repurposing to preventing myeloid malignancies
5. CRISPRi proliferation and differentiation screening to identify functional long noncoding RNAs in pediatric AML
6. Deciphering the molecular mechanism of NUP98-KDM5A chromosomal translocation in pediatric non-DS-AMKL
7. Comprehensive CRISPR-Cas9 screens identify genetic determinants of drug responsiveness in multiple myeloma
8. MicroRNA-150-regulated vectors allow lymphocyte-sparing transgene expression in hematopoietic gene therapy
9. MPN development caused by activating mutations in Mpl depends on Ras/MapK and PI3K/Akt signalling in addition to Jak/Stat signalling: V694
10. Mapping chromatin occupancy of GATA1 and RUNX1 isoforms in Down syndrome myeloid leukemia
11. Rewiring the interplay between GATA1s and secondary mutations in the leukaemogenic transformation
12. Overcoming differentiation blockage by inhibition of LSD1 as novel therapeutic strategy in pediatric AML
13. Ezh2 loss cooperates with loss of Runx1 during leukemogenesis and reactivates a fetal gene signature
14. CRISPR/Cas9-based screens identify an essential long noncoding RNA locus in pediatric acute myeloid leukemia cells
15. Investigating miR-125b target gene Arid3a in trisomy 21-associated leukemogenesis
16. Testing ABT-263 for the treatment of pediatric acute myeloid leukemia
17. Characterization of RNA-Protein Interaction Networks in Acute Leukemias
18. S146 DECIPHERING THE ROLE OF RUNX1 ISOFORMS IN THE DEVELOPMENT OF TRANSIENT ABNORMAL MYELOPOIESIS
19. PS998 JANUS KINASE AND CYTOKINE RECEPTOR MUTATIONS IN TRANSIENT ABNORMAL MYELOPOIESIS AND MYELOID LEUKEMIA IN CHILDREN WITH TRISOMY 21
20. PF208 MN1 IS INDISPENSABLE FOR MLL-REARRANGED ACUTE MYELOID LEUKEMIA
21. Cooperativity between miR-125b and Gata1 s in the pathogenesis of Down syndrome-associated myeloid leukemia
22. Establishment of new therapeutic options for the treatment of Myeloid Leukemia in Down syndrome (ML-DS)
23. Deciphering the interactive network of the DLK1-DIO3 locus in hematopoiesis and pediatric acute megakaryoblastic leukemia
24. Identification of GATA1 s interaction partners in Down syndrome-associated myeloid leukemia
25. CRISPRi screen to identify functional long noncoding RNAs in pediatric acute myeloid leukemia
26. Endogenous tumor suppressor microRNA-193b: Therapeutic and prognostic value in acute myeloid leukemia
27. Endogenous Tumor Suppressor microRNA-193b: Therapeutic and Prognostic Value in Acute Myeloid Leukemia
28. Modelling the progression of a preleukemic stage to overt leukemia in children with Down syndrome
29. Functional and molecular characterization of oncogenic dependencies on chromosome 21 in Down syndrome-associated myeloid leukemia
30. Deciphering the oncogenic network of PRC-2 loss guided leukemogenesis
31. Cooperativity between miR-125b and Gata1 s in the pathogenesis of Down syndrome-associated myeloid leukemia
32. CRISPRi screening to identify functional long noncoding RNAs in pediatric acute myeloid leukemia
33. Patient-derived xenografts for pre-clinical drug development in AML
34. Deciphering the genetically interactive network of the DLK1-DIO3 ncRNA locus in the hematopoietic system and pediatric acute megakaryoblastic leukemia
35. The non-coding RNA landscape of human hematopoiesis and leukemia
36. Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
37. The non-coding RNA landscape of human hematopoiesis and leukemia
38. Members of the miR-99/100˜125 tricistrons cooperatively induce a pre-leukemic phenotype
39. Stem cell-enriched long non-coding RNA HOXA10-AS contributes to the pathogenesis of MLL-rearranged AML
40. Deconvoluting the oncogenic interactome in Transient Abnormal Myelopoiesis (TAM)
41. Single Nucleotide Polymorphisms (SNPs) im Scarb1 Gen und deren Bedeutung für eine Hepatitis C Virus Infektion
42. Deciphering the oncogenic network of PRC-2 loss guided leukemogenesis
43. Nup98-Kdm5a, induced via CRISPR-Cas9 genome editing, transforms murine hematopoietic stem cells
44. Impact of Genetic Polymorphisms in the SCARB1 Gene on Hepatitis C Virus
45. 190 Functional screening and target validation of long non-coding RNAs regulating EMT and drug resistance to combat E2F1-induced MiM-urinary bladder carcinoma
46. Improved lentiviral CRISPR-Cas9 vectors for the generation of leukemogenic chromosomal translocations
47. Activating CSF2RB mutations contribute to TAM/ML-DS transformation
48. FRI-255 - Impact of Genetic Polymorphisms in the SCARB1 Gene on Hepatitis C Virus
49. MicroRNA-150-regulated vectors allow lymphocyte-sparing transgene expression in hematopoietic gene therapy
50. Activating CSF2RB Mutations Contribute to the Leukemic Transformation from TAM to ML-DS
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