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135 results on '"Heckemann, R. A."'

3. Classifier Selection Strategies for Label Fusion Using Large Atlas Databases

Author

Aljabar, Paul, Heckemann, R., Hammers, Alexander, Hajnal, Joseph V., Rueckert, Daniel, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Ayache, Nicholas, editor, Ourselin, Sébastien, editor, and Maeder, Anthony, editor

Published
2007
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6. Liver microbubble transit time compared with histology and Child-Pugh score in diffuse liver disease: a cross sectional study

Author

Blomley, MJK, Lim, AKP, Harvey, CJ, Patel, N, Basilico, R, Heckemann, R, Urbank, A, Cosgrove, DO, and Taylor-Robinson, SD

Subjects
Medical tests -- Methods -- Physiological aspects, Liver -- Physiological aspects -- Methods, Liver cirrhosis -- Diagnosis, Health
Abstract

Background: A previous pilot study showed that early arrival time of a microbubble in a hepatic vein is a sensitive indicator of cirrhosis. Aim: To see if this index can [...]

Published
2003

9. Ultrasound Diagnosis of Renal and Pararenal Tumors

Author

Heckemann, R., Ackermann, R., Bachmann, K. D., Baert, A., Behrendt, H., Beyer, D., Bischoff, W., Boijsen, E., Dominick, H. Chr., Fiedler, V., Fuchs, W. A., Georgi, M., Goerttler, U., Goldberg, H. I., Günther, R., Havers, W., Heckemann, R., Holfeld, H., Jeanmart, L., Kaude, J. V., Leder, L.-D., Löhr, E., Marberger, M., Marchal, G., Mellin, P., Moss, A. A., Olsson, O., Osteaux, M., Richter, H. J., Scherer, E., Stambolis, Chr., Strötges, M. W., Swart, B., Wilms, G., and Löhr, Eberhard, editor

Published
1979
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16. In-vitro- und In-vivo-Darstellungen von Punktionsinstrumenten im sonographischen Echtzeitbild - 2. Mitteilung: Plastikinstrumente

Author

Heckemann R and Seidel Kj

Subjects
Materials science, Animal model, Contrast enhancement, business.industry, In vivo, Lumen (anatomy), Radiology, Nuclear Medicine and imaging, Real time ultrasound, Ultrasonography, business, Angioplasty balloon, Biomedical engineering
Abstract

The article reports on a systematic sonographic examination of plastic puncture instruments in a water-bath and in an animal model. The plastic instruments used showed visualization of the lumen in a horizontal (longitudinal) cross-section. In an oblique longitudinal cross-section of an instrument filled homogeneously with water, only one echo generated at the tip of the instrument could be demonstrated. It was possible to achieve contrast enhancement of the plastic instrument by roughening its exterior or interior surfaces, by insufflation of air bubbles or by inhomogenization, using various plastic-cum-metal constructions. The effects produced in the water-bath were found to be similar to those observed in vivo.

Published
2008
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17. Abszeßtherapie durch ultraschallgeführte Feinnadelpunktion

Author

Wernecke K and Heckemann R

Subjects
medicine.medical_specialty, Percutaneous, business.industry, medicine, Abdominal Abscess, Radiology, Nuclear Medicine and imaging, Needle puncture, business, Abscess, medicine.disease, Ultrasound guided, Surgery
Abstract

29 intraabdominal abscesses were punctured with sonographic guidance. 26 cases were treated by an evacuating needle puncture which was curative in 23 cases (88%). The complications were temporary bacteraeminas in two cases, which were managed conservatively. Sonographically guided fine needle puncture is a simple and effective procedure for the treatment of abdominal abscesses and should be considered as an alternative to surgery and percutaneous drainage.

Published
2008
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22. The human hippocampus and amygdala: Probabilistic atlases in a stereotaxic space, and quantitative comparison of spatial normalization strategies

Author

Vial, C., Belgacem, M., Heckemann, R. A., Yankam Njiwa, J., Allom, R., Chen, C.H., Costes, N., Hammers, A., Division of Experimental Medicine, Imperial College London, Fondation neurodis, Fondation Neurodis, Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre d'Etude et de Recherche Multimodal Et Pluridisciplinaire en imagerie du vivant (CERMEP - imagerie du vivant), and Université de Lyon-Université de Lyon-CHU Grenoble-Hospices Civils de Lyon (HCL)-CHU Saint-Etienne-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)

Subjects
[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing
Published
2013

25. Atrophie de l'amygdale dans la maladie d'Alzheimer: Un nouveau marqueur?

Author

Klein Koerkamp, Y., Heckemann, R. A., Moreaud, O., Keignart, S., Krainik, A., Hammers, A., Baciu, Monica, Hot, P., Division of Experimental Medicine, Imperial College London, Fondation neurodis, Fondation Neurodis, Grenoble Institut des Neurosciences (GIN), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de neuro-radiologie, CHU Grenoble-Université Joseph Fourier - Grenoble 1 (UJF), Laboratoire de Psychologie et NeuroCognition (LPNC), and Centre National de la Recherche Scientifique (CNRS)-Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])

Subjects
ComputingMilieux_MISCELLANEOUS
Abstract

National audience

Published
2012

26. Implémentation et développement d'un outil d'analyse d'IRM: aide à la detection de lesions épilpetogènes dysplasiques

Author

Ghrenassia, S., Hammers, A., Ryvlin, P., Yankam Njiwa, J., Heckemann, R. A., Costes, N., Division of Experimental Medicine, Imperial College London, Fondation neurodis, Fondation Neurodis, Translational and integrative group in epilepsy research, Lyon Neuroscience Research center, Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre d'Etude et de Recherche Multimodal Et Pluridisciplinaire en imagerie du vivant (CERMEP - imagerie du vivant), and Université de Lyon-Université de Lyon-CHU Grenoble-Hospices Civils de Lyon (HCL)-CHU Saint-Etienne-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)

Subjects
[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing, ComputingMilieux_MISCELLANEOUS
Abstract

National audience

Published
2012

27. L'hippocampe et l'amygdale humains : Création de cartes probabilistes dans l'espace MNI, et comparaison quantitative de stratégies de normalisation spatiale

Author

Vial, C., Belgacem, M., Heckemann, R. A., Yankam Njiwa, J., Allom, R., Chen, C.H., Costes, N., Hammers, A., Division of Experimental Medicine, Imperial College London, Fondation neurodis, Fondation Neurodis, Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre d'Etude et de Recherche Multimodal Et Pluridisciplinaire en imagerie du vivant (CERMEP - imagerie du vivant), and Université de Lyon-Université de Lyon-CHU Grenoble-Hospices Civils de Lyon (HCL)-CHU Saint-Etienne-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)

Subjects
[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing, ComputingMilieux_MISCELLANEOUS
Abstract

National audience

Published
2012

33. Renal and Adrenal Tumors

Author

Ackermann, R., primary, Bachmann, K. D., additional, Baert, A., additional, Behrendt, H., additional, Beyer, D., additional, Bischoff, W., additional, Boijsen, E., additional, Dominick, H. Chr., additional, Fiedler, V., additional, Fuchs, W. A., additional, Georgi, M., additional, Goerttler, U., additional, Goldberg, H. I., additional, Günther, R., additional, Havers, W., additional, Heckemann, R., additional, Holfeld, H., additional, Jeanmart, L., additional, Kaude, J. V., additional, Leder, L.-D., additional, Löhr, E., additional, Marberger, M., additional, Marchal, G., additional, Mellin, P., additional, Moss, A. A., additional, Olsson, O., additional, Osteaux, M., additional, Richter, H. J., additional, Scherer, E., additional, Stambolis, Chr., additional, Strötges, M. W., additional, Swart, B., additional, and Wilms, G., additional

Published
1979
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38. Inflammation after trauma: Microglial activation and traumatic brain injury

Author

Ramlackhansingh, A, Brooks, D, Greenwood, R, Bose, S, Turkheimer, F, Kinnunen, K, Gentleman, S, Heckemann, R, Gunanayagam, K, Gelosa, G, Sharp, D, Sharp, D., GELOSA, GIORGIO, Ramlackhansingh, A, Brooks, D, Greenwood, R, Bose, S, Turkheimer, F, Kinnunen, K, Gentleman, S, Heckemann, R, Gunanayagam, K, Gelosa, G, Sharp, D, Sharp, D., and GELOSA, GIORGIO

Abstract

Objective: Patient outcome after traumatic brain injury (TBI) is highly variable. The underlying pathophysiology of this is poorly understood, but inflammation is potentially an important factor. Microglia orchestrate many aspects of this response. Their activation can be studied in vivo using the positron emission tomography (PET) ligand [11C](R)PK11195 (PK). In this study, we investigate whether an inflammatory response to TBI persists, and whether this response relates to structural brain abnormalities and cognitive function. Methods: Ten patients, studied at least 11 months after moderate to severe TBI, underwent PK PET and structural magnetic resonance imaging (including diffusion tensor imaging). PK binding potentials were calculated in and around the site of focal brain damage, and in selected distant and subcortical brain regions. Standardized neuropsychological tests were administered. Results: PK binding was significantly raised in the thalami, putamen, occipital cortices, and posterior limb of the internal capsules after TBI. There was no increase in PK binding at the original site of focal brain injury. High PK binding in the thalamus was associated with more severe cognitive impairment, although binding was not correlated with either the time since the injury or the extent of structural brain damage. Interpretation: We demonstrate that increased microglial activation can be present up to 17 years after TBI. This suggests that TBI triggers a chronic inflammatory response particularly in subcortical regions. This highlights the importance of considering the response to TBI as evolving over time and suggests interventions may be beneficial for longer intervals after trauma than previously assumed. © 2011 American Neurological Association.

Published
2011

45. Classifier Selection Strategies for Label Fusion Using Large Atlas Databases.

Author

Hutchison, David, Kanade, Takeo, Kittler, Josef, Kleinberg, Jon M., Mattern, Friedemann, Mitchell, John C., Naor, Moni, Nierstrasz, Oscar, Pandu Rangan, C., Steffen, Bernhard, Sudan, Madhu, Terzopoulos, Demetri, Tygar, Doug, Vardi, Moshe Y., Weikum, Gerhard, Ayache, Nicholas, Ourselin, Sébastien, Maeder, Anthony, Aljabar, Paul, and Heckemann, R.

Abstract

Structural segmentations of brain MRI can be generated by propagating manually labelled atlas images from a repository to a query subject and combining them. This method has been shown to be robust, consistent and increasingly accurate with increasing numbers of classifiers. It outperforms standard atlas-based segmentation but suffers, however, from problems of scale when the number of atlases is large. For a large repository and a particular query subject, using a selection strategy to identify good classifiers is one way to address problems of scale. This work presents and compares different classifier selection strategies which are applied to a group of 275 subjects with manually labelled brain MR images. We approximate an upper limit for the accuracy or overlap that can be achieved for a particular structure in a given subject and compare this with the accuracy obtained using classifier selection. The accuracy of different classifier selection strategies are also rated against the distribution of overlaps generated by random groups of classifiers. [ABSTRACT FROM AUTHOR]

Published
2007
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