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82,240 results on '"Hecht"'

1. Water Is K’é: Learning from the Navajo Community to Promote Early Child Health

Author

George, Carmen, John, Brianna, Goldtooth-Halwood, Renee, Hecht, Ken, Hecht, Christina, Vollmer, Laura, Benally, Louise, Yazzie, Asia Soleil, Whitman, Rachel, Egge, Malyssa, Nelson, Nora, Bitah, Kerlissa, Bennet, Eva, Mott, Olivia, Mark, Janet, Salt, Shine K., Edison, Tierra H. M., and Shin, Sonya S.

Published
2024

14. In situ experiments in microgravity and phase-field simulations of the lamellar-to-rod transition during eutectic growth

Author

Akamatsu, Silvère, Bottin-Rousseau, Sabine, Şerefoğlu, Melis, Witusiewicz, Victor T., Hecht, Ulrike, and Plapp, Mathis

Subjects
Solidification, Eutectic alloys, In situ experiments, Modeling, Microgravity, Pattern formation, Materials of engineering and construction. Mechanics of materials, TA401-492
Abstract

In recent experiments on the solidification of the binary eutectic alloy succinonitrile-(D)camphor carried out on board of the International Space Station (ISS), a transition from rod to lamellar patterns was observed for low growth velocities. The transition was interpreted in terms of a competition between a propagative instability of lamellae and a drift induced by a transverse temperature gradient. Phase-field simulations of a symmetric model alloy support this scenario: for a fixed transverse temperature gradient, the transition from rods to lamellae occurs for a critical composition at fixed velocity, and for a critical velocity at fixed composition. Since the alloy and control parameters used in experiments and simulations are different, our results strongly suggest that this morphological transition is generic for eutectic alloys.

Published
2023
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17. Residual Governance

Author

Hecht, Gabrielle

Subjects
racial capitalism, apartheid, Anthropocene, waste, technopolitics, mining, infrastructure, bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFS Social groups::JFSL Ethnic studies, bic Book Industry Communication::R Earth sciences, geography, environment, planning::RN The environment::RNK Conservation of the environment
Abstract

Diving in to the history of South African gold and uranium mining, Gabrielle Hecht shows how forms of state governance and the fight for infrastructural and environmental justice tell a global story of racial capitalism and the Anthropocene.

Published
2023
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20. Partners matter: The psychosocial well-being of couples when dealing with endometriosis

Author

Schick Maren, Germeyer Ariane, Böttcher Bettina, Hecht Stephanie, Geiser Magdalena, Rösner Sabine, Eckstein Monika, Vomstein Kilian, Toth Bettina, Strowitzki Thomas, Wischmann Tewes, and Ditzen Beate

Subjects
Endometriosis, Partnership, Psychological distress, Sexuality, Social support, Actor-partner-interdependence model, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

Abstract Background Endometriosis is often associated with severe dysmenorrhea, pelvic pain and dyspareunia and has a high impact on daily life as well as sexuality. Quality of partnership positively influences the course of various diseases and ability to cope with emotional and physical distress. However, studies focusing on the male partners of endometriosis patients are rare, and even less is known about the reciprocal relationship in these couples. Therefore, this study aims to explore the interrelations in couples with endometriosis in matters of psychological distress, sexual and partnership satisfaction and social support. Methods The cross-sectional study was conducted in two university-affiliated fertility centres in Germany and Austria with n = 104 female/male couples affected by endometriosis. Participants completed a questionnaire regarding endometriosis, partnership, sexuality, stress, anxiety, depression and social support. Both women and men were asked about the impact of women’s endometriosis-related pain (IEP) on their everyday life (e.g. leisure time). Data were analysed using the Actor-Partner-Interdependence Model. Results Significant partner effects were evident: High depression, anxiety and stress scores in women were associated with a higher IEP in men (all p ≤ 0.01), reciprocally high stress and depression scores in men were correlated with a higher IEP in women (all p ≤ 0.05). Less sexual satisfaction in women was associated with a higher IEP in men (p = 0.040). There was a significant reciprocal association between the perceived lack of understanding from the social environment and a higher IEP, for both women (p = 0.022) and men (p = 0.027). Conclusions The male partner should be taken into account when counselling or treating women with endometriosis. Our study shows a high interdependence and reciprocal influence from both partners—positively and negatively—concerning psychological distress and sexual satisfaction. Furthermore, there ought to be more awareness for the psychosocial impact of endometriosis, especially in regard to social support and understanding. Talking about and improving sexual satisfaction as well as enhancing stress reducing techniques may hold great benefits for dealing with endometriosis. Registration number The study is registered with the German Clinical Trials Register (DRKS), number DRKS00014362.

Published
2022
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21. Germanium Fabry-Perot nanoresonators investigated by cathodoluminescence spectroscopy

Author

Mignuzzi Sandro, Wu Xiaofei, Hecht Bert, Frigerio Jacopo, Isella Giovanni, Celebrano Michele, Finazzi Marco, Sapienza Riccardo, and Biagioni Paolo

Subjects
dielectric nanoantennas, cathodoluminescence spectroscopy, germanium, Applied optics. Photonics, TA1501-1820, Optics. Light, QC350-467
Abstract

We report on the experimental investigation, by means of spatially-resolved cathodoluminescence spectroscopy, of rectangular all-dielectric Ge nanoantennas sustaining Fabry-Perot resonances. The combination of spatial and spectral resolution allows us to directly image the standing-wave pattern of the local density of optical states inside the nanoantennas, which is the fingerprint of the resonant Purcell contribution to the overall emission enhancement previously reported in the literature for the same structures. Our results confirm that the emission properties of Ge nanostructures can be effectively tuned by engineering the local density of optical states and that cathodoluminescence provides valuable information to experimentally address such modulation in their emission properties.

Published
2024
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25. The putative center in NGC 1052

Author

Baczko, Anne-Kathrin, Kadler, Matthias, Ros, Eduardo, Fromm, Christian M., Wielgus, Maciek, Perucho, Manel, Krichbaum, Thomas P., Baloković, Mislav, Blackburn, Lindy, Chan, Chi-kwan, Issaoun, Sara, Janssen, Michael, Ricci, Luca, Akiyama, Kazunori, Albentosa-Ruíz, Ezequiel, Alberdi, Antxon, Alef, Walter, Algaba, Juan Carlos, Anantua, Richard, Asada, Keiichi, Azulay, Rebecca, Bach, Uwe, Ball, David, Bandyopadhyay, Bidisha, Barrett, John, Bauböck, Michi, Benson, Bradford A., Bintley, Dan, Blundell, Raymond, Bouman, Katherine L., Bower, Geoffrey C., Boyce, Hope, Bremer, Michael, Brinkerink, Christiaan D., Brissenden, Roger, Britzen, Silke, Broderick, Avery E., Broguiere, Dominique, Bronzwaer, Thomas, Bustamante, Sandra, Byun, Do-Young, Carlstrom, John E., Ceccobello, Chiara, Chael, Andrew, Chang, Dominic O., Chatterjee, Koushik, Chatterjee, Shami, Chen, Ming-Tang, Chen, Yongjun, Cheng, Xiaopeng, Cho, Ilje, Christian, Pierre, Conroy, Nicholas S., Conway, John E., Cordes, James M., Crawford, Thomas M., Crew, Geoffrey B., Cruz-Osorio, Alejandro, Cui, Yuzhu, Dahale, Rohan, Davelaar, Jordy, De Laurentis, Mariafelicia, Deane, Roger, Dempsey, Jessica, Desvignes, Gregory, Dexter, Jason, Dhruv, Vedant, Dihingia, Indu K., Doeleman, Sheperd S., Dougall, Sean Taylor, Dzib, Sergio A., Eatough, Ralph P., Emami, Razieh, Falcke, Heino, Farah, Joseph, Fish, Vincent L., Fomalont, Edward, Ford, H. Alyson, Foschi, Marianna, Fraga-Encinas, Raquel, Freeman, William T., Friberg, Per, Fuentes, Antonio, Galison, Peter, Gammie, Charles F., García, Roberto, Gentaz, Olivier, Georgiev, Boris, Goddi, Ciriaco, Gold, Roman, Gómez-Ruiz, Arturo I., Gómez, José L., Gu, Minfeng, Gurwell, Mark, Hada, Kazuhiro, Haggard, Daryl, Haworth, Kari, Hecht, Michael H., Hesper, Ronald, Heumann, Dirk, Ho, Luis C., Ho, Paul, Honma, Mareki, Huang, Chih-Wei L., Huang, Lei, Hughes, David H., Impellizzeri, C. M. Violette, Inoue, Makoto, James, David J., Jannuzi, Buell T., Jeter, Britton, Jiang, Wu, Jiménez-Rosales, Alejandra, Johnson, Michael D., Jorstad, Svetlana, Joshi, Abhishek V., Jung, Taehyun, Karami, Mansour, Karuppusamy, Ramesh, Kawashima, Tomohisa, Keating, Garrett K., Kettenis, Mark, Kim, Dong-Jin, Kim, Jae-Young, Kim, Jongsoo, Kim, Junhan, Kino, Motoki, Koay, Jun Yi, Kocherlakota, Prashant, Kofuji, Yutaro, Koyama, Shoko, Kramer, Carsten, Kramer, Joana A., Kramer, Michael, Kuo, Cheng-Yu, La Bella, Noemi, Lauer, Tod R., Lee, Daeyoung, Lee, Sang-Sung, Leung, Po Kin, Levis, Aviad, Li, Zhiyuan, Lico, Rocco, Lindahl, Greg, Lindqvist, Michael, Lisakov, Mikhail, Liu, Jun, Liu, Kuo, Liuzzo, Elisabetta, Lo, Wen-Ping, Lobanov, Andrei P., Loinard, Laurent, Lonsdale, Colin J., Lowitz, Amy E., Lu, Ru-Sen, MacDonald, Nicholas R., Mao, Jirong, Marchili, Nicola, Markoff, Sera, Marrone, Daniel P., Marscher, Alan P., Martí-Vidal, Iván, Matsushita, Satoki, Matthews, Lynn D., Medeiros, Lia, Menten, Karl M., Michalik, Daniel, Mizuno, Izumi, Mizuno, Yosuke, Moran, James M., Moriyama, Kotaro, Moscibrodzka, Monika, Mulaudzi, Wanga, Müller, Cornelia, Müller, Hendrik, Mus, Alejandro, Musoke, Gibwa, Myserlis, Ioannis, Nadolski, Andrew, Nagai, Hiroshi, Nagar, Neil M., Nair, Dhanya G., Nakamura, Masanori, Narayanan, Gopal, Natarajan, Iniyan, Nathanail, Antonios, Fuentes, Santiago Navarro, Neilsen, Joey, Neri, Roberto, Ni, Chunchong, Noutsos, Aristeidis, Nowak, Michael A., Oh, Junghwan, Okino, Hiroki, Sánchez, Héctor Raúl Olivares, Ortiz-León, Gisela N., Oyama, Tomoaki, Özel, Feryal, Palumbo, Daniel C. M., Paraschos, Georgios Filippos, Park, Jongho, Parsons, Harriet, Patel, Nimesh, Pen, Ue-Li, Pesce, Dominic W., Piétu, Vincent, Plambeck, Richard, PopStefanija, Aleksandar, Porth, Oliver, Pötzl, Felix M., Prather, Ben, Preciado-López, Jorge A., Principe, Giacomo, Psaltis, Dimitrios, Pu, Hung-Yi, Ramakrishnan, Venkatessh, Rao, Ramprasad, Rawlings, Mark G., Raymond, Alexander W., Ricarte, Angelo, Ripperda, Bart, Roelofs, Freek, Rogers, Alan, Romero-Cañizales, Cristina, Roshanineshat, Arash, Rottmann, Helge, Roy, Alan L., Ruiz, Ignacio, Ruszczyk, Chet, Rygl, Kazi L. J., Sánchez, Salvador, Sánchez-Argüelles, David, Sánchez-Portal, Miguel, Sasada, Mahito, Satapathy, Kaushik, Savolainen, Tuomas, Schloerb, F. Peter, Schonfeld, Jonathan, Schuster, Karl-Friedrich, Shao, Lijing, Shen, Zhiqiang, Small, Des, Sohn, Bong Won, SooHoo, Jason, Salas, León David Sosapanta, Souccar, Kamal, Stanway, Joshua S., Sun, He, Tazaki, Fumie, Tetarenko, Alexandra J., Tiede, Paul, Tilanus, Remo P. J., Titus, Michael, Torne, Pablo, Toscano, Teresa, Traianou, Efthalia, Trent, Tyler, Trippe, Sascha, Turk, Matthew, van Bemmel, Ilse, van Langevelde, Huib Jan, van Rossum, Daniel R., Vos, Jesse, Wagner, Jan, Ward-Thompson, Derek, Wardle, John, Washington, Jasmin E., Weintroub, Jonathan, Wharton, Robert, Wiik, Kaj, Witzel, Gunther, Wondrak, Michael F., Wong, George N., Wu, Qingwen, Yadlapalli, Nitika, Yamaguchi, Paul, Yfantis, Aristomenis, Yoon, Doosoo, Young, André, Young, Ken, Younsi, Ziri, Yu, Wei, Yuan, Feng, Yuan, Ye-Fei, Zensus, J. Anton, Zhang, Shuo, and Zhao, Guang-Yao

Subjects
Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Astrophysics of Galaxies
Abstract

Many active galaxies harbor powerful relativistic jets, however, the detailed mechanisms of their formation and acceleration remain poorly understood. To investigate the area of jet acceleration and collimation with the highest available angular resolution, we study the innermost region of the bipolar jet in the nearby low-ionization nuclear emission-line region (LINER) galaxy NGC 1052. We combined observations of NGC 1052 taken with VLBA, GMVA, and EHT over one week in the spring of 2017. For the first time, NGC 1052 was detected with the EHT, providing a size of the central region in-between both jet bases of 250 RS (Schwarzschild radii) perpendicular to the jet axes. This size estimate supports previous studies of the jets expansion profile which suggest two breaks of the profile at around 300 RS and 10000 RS distances to the core. Furthermore, we estimated the magnetic field to be 1.25 Gauss at a distance of 22 {\mu}as from the central engine by fitting a synchrotron-self absorption spectrum to the innermost emission feature, which shows a spectral turn-over at about 130 GHz. Assuming a purely poloidal magnetic field, this implies an upper limit on the magnetic field strength at the event horizon of 26000 Gauss, which is consistent with previous measurements. The complex, low-brightness, double-sided jet structure in NGC 1052 makes it a challenge to detect the source at millimeter (mm) wavelengths. However, our first EHT observations have demonstrated that detection is possible up to at least 230 GHz. This study offers a glimpse through the dense surrounding torus and into the innermost central region, where the jets are formed. This has enabled us to finally resolve this region and provide improved constraints on its expansion and magnetic field strength., Comment: 22 pages, 10 figures, published in A&A

Published
2025
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26. A multi-frequency study of sub-parsec jets with the Event Horizon Telescope

Author

Röder, Jan, Wielgus, Maciek, Lobanov, Andrei P., Krichbaum, Thomas P., Nair, Dhanya G., Lee, Sang-Sung, Ros, Eduardo, Fish, Vincent L., Blackburn, Lindy, Chan, Chi-kwan, Issaoun, Sara, Janssen, Michael, Johnson, Michael D., Doeleman, Sheperd S., Bower, Geoffrey C., Crew, Geoffrey B., Tilanus, Remo P. J., Savolainen, Tuomas, Impellizzeri, C. M. Violette, Alberdi, Antxon, Baczko, Anne-Kathrin, Gómez, José L., Lu, Ru-Sen, Paraschos, Georgios F., Traianou, Efthalia, Goddi, Ciriaco, Kim, Daewon, Lisakov, Mikhail, Kovalev, Yuri Y., Voitsik, Petr A., Sokolovsky, Kirill V., Akiyama, Kazunori, Albentosa-Ruíz, Ezequiel, Alef, Walter, Algaba, Juan Carlos, Anantua, Richard, Asada, Keiichi, Azulay, Rebecca, Bach, Uwe, Ball, David, Baloković, Mislav, Bandyopadhyay, Bidisha, Barrett, John, Bauböck, Michi, Benson, Bradford A., Bintley, Dan, Blundell, Raymond, Bouman, Katherine L., Bremer, Michael, Brinkerink, Christiaan D., Brissenden, Roger, Britzen, Silke, Broderick, Avery E., Broguiere, Dominique, Bronzwaer, Thomas, Bustamante, Sandra, Byun, Do-Young, Carlstrom, John E., Ceccobello, Chiara, Chael, Andrew, Chang, Dominic O., Chatterjee, Koushik, Chatterjee, Shami, Chen, Ming-Tang, Chen, Yongjun, Cheng, Xiaopeng, Cho, Ilje, Christian, Pierre, Conroy, Nicholas S., Conway, John E., Cordes, James M., Crawford, Thomas M., Cruz-Osorio, Alejandro, Cui, Yuzhu, Curd, Brandon, Dahale, Rohan, Davelaar, Jordy, De Laurentis, Mariafelicia, Deane, Roger, Dempsey, Jessica, Desvignes, Gregory, Dexter, Jason, Dhruv, Vedant, Dihingia, Indu K., Dougall, Sean Taylor, Dzib, Sergio A., Eatough, Ralph P., Emami, Razieh, Falcke, Heino, Farah, Joseph, Fomalont, Edward, Ford, H. Alyson, Foschi, Marianna, Fraga-Encinas, Raquel, Freeman, William T., Friberg, Per, Fromm, Christian M., Fuentes, Antonio, Galison, Peter, Gammie, Charles F., García, Roberto, Gentaz, Olivier, Georgiev, Boris, Gold, Roman, Gómez-Ruiz, Arturo I., Gu, Minfeng, Gurwell, Mark, Hada, Kazuhiro, Haggard, Daryl, Haworth, Kari, Hecht, Michael H., Hesper, Ronald, Heumann, Dirk, Ho, Luis C., Ho, Paul, Honma, Mareki, Huang, Chih-Wei L., Huang, Lei, Hughes, David H., Ikeda, Shiro, Inoue, Makoto, James, David J., Jannuzi, Buell T., Jeter, Britton, Jiang, Wu, Jiménez-Rosales, Alejandra, Jorstad, Svetlana, Joshi, Abhishek V., Jung, Taehyun, Karami, Mansour, Karuppusamy, Ramesh, Kawashima, Tomohisa, Keating, Garrett K., Kettenis, Mark, Kim, Dong-Jin, Kim, Jae-Young, Kim, Jongsoo, Kim, Junhan, Kino, Motoki, Koay, Jun Yi, Kocherlakota, Prashant, Kofuji, Yutaro, Koyama, Shoko, Kramer, Carsten, Kramer, Joana A., Kramer, Michael, Kuo, Cheng-Yu, La Bella, Noemi, Lauer, Tod R., Lee, Daeyoung, Leung, Po Kin, Levis, Aviad, Li, Zhiyuan, Lico, Rocco, Lindahl, Greg, Lindqvist, Michael, Liu, Jun, Liu, Kuo, Liuzzo, Elisabetta, Lo, Wen-Ping, Loinard, Laurent, Lonsdale, Colin J., Lowitz, Amy E., MacDonald, Nicholas R., Mao, Jirong, Marchili, Nicola, Markoff, Sera, Marrone, Daniel P., Marscher, Alan P., Martí-Vidal, Iván, Matsushita, Satoki, Matthews, Lynn D., Medeiros, Lia, Menten, Karl M., Michalik, Daniel, Mizuno, Izumi, Mizuno, Yosuke, Moran, James M., Moriyama, Kotaro, Moscibrodzka, Monika, Mulaudzi, Wanga, Müller, Cornelia, Müller, Hendrik, Mus, Alejandro, Musoke, Gibwa, Myserlis, Ioannis, Nadolski, Andrew, Nagai, Hiroshi, Nagar, Neil M., Nakamura, Masanori, Narayanan, Gopal, Natarajan, Iniyan, Nathanail, Antonios, Fuentes, Santiago Navarro, Neilsen, Joey, Neri, Roberto, Ni, Chunchong, Noutsos, Aristeidis, Nowak, Michael A., Oh, Junghwan, Okino, Hiroki, Sánchez, Héctor R. Olivares, Ortiz-León, Gisela N., Oyama, Tomoaki, özel, Feryal, Palumbo, Daniel C. M., Park, Jongho, Parsons, Harriet, Patel, Nimesh, Pen, Ue-Li, Pesce, Dominic W., Piétu, Vincent, Plambeck, Richard, PopStefanija, Aleksandar, Porth, Oliver, Pötzl, Felix M., Prather, Ben, Preciado-López, Jorge A., Principe, Giacomo, Psaltis, Dimitrios, Pu, Hung-Yi, Ramakrishnan, Venkatessh, Rao, Ramprasad, Rawlings, Mark G., Ricarte, Angelo, Ripperda, Bart, Roelofs, Freek, Rogers, Alan, Romero-Cañizales, Cristina, Roshanineshat, Arash, Rottmann, Helge, Roy, Alan L., Ruiz, Ignacio, Ruszczyk, Chet, Rygl, Kazi L. J., Sánchez, Salvador, Sánchez-Argüelles, David, Sánchez-Portal, Miguel, Sasada, Mahito, Satapathy, Kaushik, Schloerb, F. Peter, Schonfeld, Jonathan, Schuster, Karl-Friedrich, Shao, Lijing, Shen, Zhiqiang, Small, Des, Sohn, Bong Won, SooHoo, Jason, Salas, León David Sosapanta, Souccar, Kamal, Stanway, Joshua S., Sun, He, Tazaki, Fumie, Tetarenko, Alexandra J., Tiede, Paul, Titus, Michael, Torne, Pablo, Toscano, Teresa, Trent, Tyler, Trippe, Sascha, Turk, Matthew, van Bemmel, Ilse, van Langevelde, Huib J., van Rossum, Daniel R., Vos, Jesse, Wagner, Jan, Ward-Thompson, Derek, Wardle, John, Washington, Jasmin E., Weintroub, Jonathan, Wharton, Robert, Wiik, Kaj, Witzel, Gunther, Wondrak, Michael F., Wong, George N., Wu, Qingwen, Yadlapalli, Nitika, Yamaguchi, Paul, Yfantis, Aristomenis, Yoon, Doosoo, Young, André, Young, Ken, Younsi, Ziri, Yu, Wei, Yuan, Feng, Yuan, Ye-Fei, Zensus, J. Anton, Zhang, Shuo, Zhao, Guang-Yao, and Zhao, Shan-Shan

Subjects
Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Astrophysics of Galaxies, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

The 2017 observing campaign of the Event Horizon Telescope (EHT) delivered the first very long baseline interferometry (VLBI) images at the observing frequency of 230 GHz, leading to a number of unique studies on black holes and relativistic jets from active galactic nuclei (AGN). In total, eighteen sources were observed: the main science targets, Sgr A* and M87 along with various calibrators. We investigated the morphology of the sixteen AGN in the EHT 2017 data set, focusing on the properties of the VLBI cores: size, flux density, and brightness temperature. We studied their dependence on the observing frequency in order to compare it with the Blandford-K\"onigl (BK) jet model. We modeled the source structure of seven AGN in the EHT 2017 data set using linearly polarized circular Gaussian components and collected results for the other nine AGN from dedicated EHT publications, complemented by lower frequency data in the 2-86 GHz range. Then, we studied the dependences of the VLBI core flux density, size, and brightness temperature on the frequency measured in the AGN host frame. We compared the observations with the BK jet model and estimated the magnetic field strength dependence on the distance from the central black hole. Our results indicate a deviation from the standard BK model, particularly in the decrease of the brightness temperature with the observing frequency. Either bulk acceleration of the jet material, energy transfer from the magnetic field to the particles, or both are required to explain the observations.

Published
2025

27. Post-Quantum Key Agreement Protocols Based on Modified Matrix-Power Functions over Singular Random Integer Matrix Semirings

Author

Hecht, Juan Pedro and Scolnik, Hugo Daniel

Subjects
Computer Science - Cryptography and Security
Abstract

Post-quantum cryptography is essential for securing digital communications against threats posed by quantum computers. Re-searchers have focused on developing algorithms that can withstand attacks from both classical and quantum computers, thereby ensuring the security of data transmissions over public networks. A critical component of this security is the key agreement protocol, which allows two parties to establish a shared secret key over an insecure channel. This paper introduces two novel post-quantum key agreement protocols that can be easily implemented on standard computers using rectangular or rank-deficient matrices, exploiting the generalizations of the matrix power function, which is a generator of NP-hard problems. We provide basic concepts and proofs, pseudocodes, examples, and a discussion of complexity., Comment: 17 Pages, 2 Figures, 1 Table

Published
2025
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28. The Use of Inhaled Epoprostenol for Acute Respiratory Distress Syndrome Secondary due to COVID-19: A Case Series

Author

Imtiaz Komal, Jodeh Wade, Sudekum Dave, DiGiovine Bruno, and Hecht Jason

Subjects
epoprostenol, acute respiratory distress syndrome, severe acute respiratory syndrome, coronavirus, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Inhaled epoprostenol (iEpo) is a pulmonary vasodilator used to treat refractory respiratory failure, including that caused by Coronavirus 2019 (COVID-19) pneumonia.

Published
2021
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29. Hardness of approximation for ground state problems

Author

Gharibian, Sevag and Hecht, Carsten

Subjects
Quantum Physics, Computer Science - Computational Complexity
Abstract

After nearly two decades of research, the question of a quantum PCP theorem for quantum Constraint Satisfaction Problems (CSPs) remains wide open. As a result, proving QMA-hardness of approximation for ground state energy estimation has remained elusive. Recently, it was shown [Bittel, Gharibian, Kliesch, CCC 2023] that a natural problem involving variational quantum circuits is QCMA-hard to approximate within ratio N^(1-eps) for any eps > 0 and N the input size. Unfortunately, this problem was not related to quantum CSPs, leaving the question of hardness of approximation for quantum CSPs open. In this work, we show that if instead of focusing on ground state energies, one considers computing properties of the ground space, QCMA-hardness of computing ground space properties can be shown. In particular, we show that it is (1) QCMA-complete within ratio N^(1-eps) to approximate the Ground State Connectivity problem (GSCON), and (2) QCMA-hard within the same ratio to estimate the amount of entanglement of a local Hamiltonian's ground state, denoted Ground State Entanglement (GSE). As a bonus, a simplification of our construction yields NP-completeness of approximation for a natural k-SAT reconfiguration problem, to be contrasted with the recent PCP-based PSPACE hardness of approximation results for a different definition of k-SAT reconfiguration [Karthik C.S. and Manurangsi, 2023, and Hirahara, Ohsaka, STOC 2024].

Published
2024

32. An Evaluation of the Performance of Stopping Rules in AI-Aided Screening for Psychological Meta-Analytical Research

Author

Lars König, Steffen Zitzmann, Tim Fütterer, Diego G. Campos, Ronny Scherer, and Martin Hecht

Abstract

Several AI-aided screening tools have emerged to tackle the ever-expanding body of literature. These tools employ active learning, where algorithms sort abstracts based on human feedback. However, researchers using these tools face a crucial dilemma: When should they stop screening without knowing the proportion of relevant studies? Although numerous stopping rules have been proposed to guide users in this decision, they have yet to undergo comprehensive evaluation. In this study, we evaluated the performance of three stopping rules: the knee method, a data-driven heuristic, and a prevalence estimation technique. We measured performance via sensitivity, specificity, and screening cost and explored the influence of the prevalence of relevant studies and the choice of the learning algorithm. We curated a dataset of abstract collections from meta-analyses across five psychological research domains. Our findings revealed performance differences between stopping rules regarding all performance measures and variations in the performance of stopping rules across different prevalence ratios. Moreover, despite the relatively minor impact of the learning algorithm, we found that specific combinations of stopping rules and learning algorithms were most effective for certain prevalence ratios of relevant abstracts. Based on these results, we derived practical recommendations for users of AI-aided screening tools. Furthermore, we discuss possible implications and offer suggestions for future research.

Published
2024
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33. Driving plasmonic nanoantennas at perfect impedance matching using generalized coherent perfect absorption

Author

Grimm Philipp, Razinskas Gary, Huang Jer-Shing, and Hecht Bert

Subjects
coherent perfect absorption, impedance matching, plasmonics, nanoantenna, Physics, QC1-999
Abstract

Coherent perfect absorption (CPA) describes the absence of all outgoing modes from a lossy resonator, driven by lossless incoming modes. Here, we show that for nanoresonators that also exhibit radiative losses, e.g., plasmonic nanoantennas, a generalized version of CPA (gCPA) can be applied. In gCPA outgoing modes are suppressed only for a subset of (guided plasmonic) modes while other (radiative) modes are treated as additional loss channels - a situation typically referred to as perfect impedance matching. Here we make use of gCPA to show how to achieve perfect impedance matching between a single nanowire plasmonic waveguide and a plasmonic nanoantenna. Antennas with both radiant and subradiant characteristics are considered. We further demonstrate potential applications in background-free sensing.

Published
2021
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35. Immunological and molecular features of the tumor microenvironment of long-term survivors of ovarian cancer

Author

Nelson, Brad H, Hamilton, Phineas T, Phung, Minh Tung, Milne, Katy, Harris, Bronwyn, Thornton, Shelby, Stevens, Donald LI, Kalaria, Shreena, Singh, Karanvir, Laumont, Céline M, Moss, Elena, Alimujiang, Aliya, Meagher, Nicola S, Bolithon, Adelyn, Fereday, Sian, Kennedy, Catherine J, Hendley, Joy, Ariyaratne, Dinuka, Alsop, Kathryn, Traficante, Nadia, Goode, Ellen L, Karnezis, Anthony N, Shen, Hui, Richardson, Jean, Deurloo, Cindy McKinnon, Chase, Anne, Grout, Bronwyn, Doherty, Jennifer A, Harris, Holly R, Cushing-Haugen, Kara L, Anglesio, Michael S, Heinze, Karolin, Huntsman, David, Talhouk, Aline, Hanley, Gillian E, Alsop, Jennifer, Jimenez-Linan, Mercedes, Pharoah, Paul DP, Boros, Jessica, Brand, Alison H, Harnett, Paul R, Sharma, Raghwa, Hecht, Jonathan L, Sasamoto, Naoko, Terry, Kathryn L, Karlan, Beth Y, Lester, Jenny, Carney, Michael E, Goodman, Marc T, Hernandez, Brenda Y, Wilkens, Lynne R, Behrens, Sabine, Fortner, Renée Turzanski, Fasching, Peter A, Bisinotto, Christiani, dos Reis, Francisco José Candido, Ghatage, Prafull, Köbel, Martin, Elishaev, Esther, Modugno, Francesmary, Cook, Linda S, Le, Nhu D, Gentry-Maharaj, Aleksandra, Menon, Usha, García, María J, Rodriguez-Antona, Cristina, Farrington, Kyo M, Kelemen, Linda E, Kommoss, Stefan, Staebler, Annette, Garsed, Dale W, Brenton, James D, Piskorz, Anna M, Bowtell, David DL, DeFazio, Anna, Ramus, Susan J, Pike, Malcolm C, and Pearce, Celeste Leigh

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Immunology, Cancer, Women's Health, Ovarian Cancer, Rare Diseases, Orphan Drug, Humans, Female, Tumor Microenvironment, Ovarian Neoplasms, Cancer Survivors, Middle Aged, Aged, CD8-Positive T-Lymphocytes, Neoplasm Proteins, Adult, Cellular immune response, Epidemiology, Oncology, Medical and Health Sciences, Biological sciences, Biomedical and clinical sciences, Health sciences
Abstract

BACKGROUNDDespite an overall poor prognosis, about 15% of patients with advanced-stage tubo-ovarian high-grade serous carcinoma (HGSC) survive 10 or more years after standard treatment.METHODSWe evaluated the tumor microenvironment of this exceptional, understudied group using a large international cohort enriched for long-term survivors (LTS; 10+ years; n = 374) compared with mid-term (MTS; 5-7.99 years; n = 433) and short-term survivors (STS; 2-4.99 years; n = 416). Primary tumor samples were immunostained and scored for intraepithelial and intrastromal densities of 10 immune-cell subsets (including T cells, B cells, plasma cells, myeloid cells, PD-1+ cells, and PD-L1+ cells) and epithelial content.RESULTSPositive associations with LTS compared with STS were seen for 9 of 10 immune-cell subsets. In particular, the combination of intraepithelial CD8+ T cells and intrastromal B cells showed near 5-fold increased odds of LTS compared with STS. All of these associations were stronger in tumors with high epithelial content and/or the C4/Differentiated molecular subtype, despite immune-cell densities generally being higher in tumors with low epithelial content and/or the C2/Immunoreactive molecular subtype.CONCLUSIONThe tumor microenvironment of HGSC LTS is distinguished by the intersection of T and B cell coinfiltration, high epithelial content, and C4/differentiated molecular subtype, features which may inspire new approaches to immunotherapy.FUNDINGOvarian Cancer Research Program (OCRP) of the Congressionally Directed Medical Research Program (CDMRP), U.S. Department of Defense (DOD); American Cancer Society; BC Cancer Foundation; Canada's Networks of Centres of Excellence; Canadian Cancer Society; Canadian Institutes of Health Research; Cancer Councils of New South Wales, Victoria, Queensland, South Australia, and Tasmania, Cancer Foundation of Western Australia; Cancer Institute NSW; Cancer Research UK; Deutsche Forschungsgesellschaft; ELAN Funds of the University of Erlangen-Nuremberg; Fred C. and Katherine B. Andersen Foundation; Genome BC; German Cancer Research Center; German Federal Ministry of Education and Research, Programme of Clinical Biomedical Research; Instituto de Salud Carlos III; Mayo Foundation; Minnesota Ovarian Cancer Alliance; Ministerio de Economía y Competitividad; Medical Research Council (MRC); National Center for Advancing Translational Sciences; National Health and Medical Research Council of Australia (NHMRC); Ovarian Cancer Australia; Peter MacCallum Foundation; Sydney West Translational Cancer Research Centre; Terry Fox Research Institute; The Eve Appeal (The Oak Foundation); UK National Institute for Health Research Biomedical Research Centres at the University of Cambridge; University of Pittsburgh School of Medicine; U.S. National Cancer Institute of the National Institutes of Health; VGH & UBC Hospital Foundation; Victorian Cancer Agency.

Published
2024

36. Rapid biphasic decay of intact and defective HIV DNA reservoir during acute treated HIV disease.

Author

Barbehenn, Alton, Shi, Lei, Shao, Junzhe, Hoh, Rebecca, Hartig, Heather, Pae, Vivian, Sarvadhavabhatla, Sannidhi, Donaire, Sophia, Sheikhzadeh, Caroline, Milush, Jeffrey, Laird, Gregory, Mathias, Mignot, Ritter, Kristen, Peluso, Michael, Martin, Jeffrey, Hecht, Frederick, Pilcher, Christopher, Cohen, Stephanie, Buchbinder, Susan, Havlir, Diane, Gandhi, Monica, Henrich, Timothy, Hatano, Hiroyu, Wang, Jingshen, Deeks, Steven, and Lee, Sulggi

Subjects
Humans, HIV Infections, DNA, Viral, Viral Load, CD4-Positive T-Lymphocytes, HIV-1, Male, Female, Virus Latency, Adult, CD4 Lymphocyte Count, Middle Aged, Anti-HIV Agents, Longitudinal Studies, Acute Disease, Models, Theoretical
Abstract

Despite antiretroviral therapy (ART), HIV persists in latently-infected cells (the HIV reservoir) which decay slowly over time. Here, leveraging >500 longitudinal samples from 67 people living with HIV (PLWH) treated during acute infection, we developed a mathematical model to predict reservoir decay from peripheral CD4 + T cells. Nonlinear generalized additive models demonstrated rapid biphasic decay of intact DNA (week 0-5: t1/2 ~ 2.83 weeks; week 5-24: t1/2 ~ 15.4 weeks) that extended out to 1 year. These estimates were ~5-fold faster than prior decay estimates among chronic treated PLWH. Defective DNA had a similar biphasic pattern, but data were more variable. Predicted intact and defective decay rates were faster for PLWH with earlier timing of ART initiation, higher initial CD4 + T cell count, and lower pre-ART viral load. In this study, we advanced our limited understanding of HIV reservoir decay at the time of ART initiation, informing future curative strategies targeting this critical time.

Published
2024

37. Household Food Insecurity Is Associated with Parental Perceptions of and Student Participation in School Meals.

Author

Zuercher, Monica, Cohen, Juliana, Hecht, Christina, Hecht, Kenneth, Orta-Aleman, Dania, Olarte, Deborah, Chapman, Leah, Read, Margaret, Ritchie, Lorrene, and Gosliner, Wendi

Subjects
NSLP, SBP, food insecurity, parental perceptions, universal school meals, Humans, Food Insecurity, Child, Female, Schools, Male, Parents, Food Services, Students, California, Family Characteristics, Meals, Adult, Adolescent, Perception, Food Supply
Abstract

BACKGROUND/OBJECTIVES: School meals are an important source of nutrition for children and have been found to help mitigate food insecurity. This study evaluated the association between food insecurity and school meal participation and whether parental perceptions about school meals differ by food security status. METHODS: In May 2022, 1110 Californian parents of K-12 students shared their perceptions about school meals, including meal quality, healthiness, stigma, and benefits, as well as their childs participation in school meals, in an online survey. Household food security was determined using the USDA 6-item module. Logistic and Poisson regression models were used for analysis. RESULTS: The prevalence of household food insecurity was 56.2% (69.6% in households of students eligible for free meals, 55.9% in reduced-price, and 38.3% in non-eligible). Many of the reported benefits of school meals (saving families money and time) were equally highly endorsed by parents with and without food insecurity (p > 0.05). Parents reporting food insecurity had less favorable perceptions of school meals and perceived more stigma (p < 0.05). Food insecurity was positively associated with breakfast participation, especially among elementary school students and students not eligible for free or reduced-price meals (FRPMs) (p < 0.05). CONCLUSIONS: Food insecurity is prevalent among California families with school-age children, even in families not eligible for federal FRPMs. Food-insecure households have more negative perceptions of school meals and experience more stigma, though they also report higher breakfast participation. Improving school meal quality and appeal, ensuring parents are familiar with meal quality and healthfulness, and reducing stigma may ease food insecurity while improving childrens health.

Published
2024

38. Scaling limits for a population model with growth, division and cross-diffusion

Author

Doumic, Marie, Hecht, Sophie, Hoffmann, Marc, and Peurichard, Diane

Subjects
Mathematics - Analysis of PDEs, Mathematics - Probability
Abstract

Originally motivated by the morphogenesis of bacterial microcolonies, the aim of this article is to explore models through different scales for a spatial population of interacting, growing and dividing particles. We start from a microscopic stochastic model, write the corresponding stochastic differential equation satisfied by the empirical measure, and rigorously derive its mesoscopic (mean-field) limit. Under smoothness and symmetry assumptions for the interaction kernel, we then obtain entropy estimates, which provide us with a localization limit at the macroscopic level. Finally, we perform a thorough numerical study in order to compare the three modeling scales.

Published
2024

39. First Very Long Baseline Interferometry Detections at 870{\mu}m

Author

Raymond, Alexander W., Doeleman, Sheperd S., Asada, Keiichi, Blackburn, Lindy, Bower, Geoffrey C., Bremer, Michael, Broguiere, Dominique, Chen, Ming-Tang, Crew, Geoffrey B., Dornbusch, Sven, Fish, Vincent L., García, Roberto, Gentaz, Olivier, Goddi, Ciriaco, Han, Chih-Chiang, Hecht, Michael H., Huang, Yau-De, Janssen, Michael, Keating, Garrett K., Koay, Jun Yi, Krichbaum, Thomas P., Lo, Wen-Ping, Matsushita, Satoki, Matthews, Lynn D., Moran, James M., Norton, Timothy J., Patel, Nimesh, Pesce, Dominic W., Ramakrishnan, Venkatessh, Rottmann, Helge, Roy, Alan L., Sánchez, Salvador, Tilanus, Remo P. J., Titus, Michael, Torne, Pablo, Wagner, Jan, Weintroub, Jonathan, Wielgus, Maciek, Young, André, Akiyama, Kazunori, Albentosa-Ruíz, Ezequiel, Alberdi, Antxon, Alef, Walter, Algaba, Juan Carlos, Anantua, Richard, Azulay, Rebecca, Bach, Uwe, Baczko, Anne-Kathrin, Ball, David, Baloković, Mislav, Bandyopadhyay, Bidisha, Barrett, John, Bauböck, Michi, Benson, Bradford A., Bintley, Dan, Blundell, Raymond, Bouman, Katherine L., Boyce, Hope, Brissenden, Roger, Britzen, Silke, Broderick, Avery E., Bronzwaer, Thomas, Bustamante, Sandra, Carlstrom, John E., Chael, Andrew, Chan, Chi-kwan, Chang, Dominic O., Chatterjee, Koushik, Chatterjee, Shami, Chen, Yongjun, Cheng, Xiaopeng, Cho, Ilje, Christian, Pierre, Conroy, Nicholas S., Conway, John E., Crawford, Thomas M., Cruz-Osorio, Alejandro, Cui, Yuzhu, Dahale, Rohan, Davelaar, Jordy, De Laurentis, Mariafelicia, Deane, Roger, Dempsey, Jessica, Desvignes, Gregory, Dexter, Jason, Dhruv, Vedant, Dihingia, Indu K., Dzib, Sergio A., Eatough, Ralph P., Emami, Razieh, Falcke, Heino, Farah, Joseph, Fomalont, Edward, Fontana, Anne-Laure, Ford, H. Alyson, Foschi, Marianna, Fraga-Encinas, Raquel, Freeman, William T., Friberg, Per, Fromm, Christian M., Fuentes, Antonio, Galison, Peter, Gammie, Charles F., Georgiev, Boris, Gold, Roman, Gómez-Ruiz, Arturo I., Gómez, José L., Gu, Minfeng, Gurwell, Mark, Hada, Kazuhiro, Haggard, Daryl, Hesper, Ronald, Heumann, Dirk, Ho, Luis C., Ho, Paul, Honma, Mareki, Huang, Chih-Wei L., Huang, Lei, Hughes, David H., Ikeda, Shiro, Impellizzeri, C. M. Violette, Inoue, Makoto, Issaoun, Sara, James, David J., Jannuzi, Buell T., Jeter, Britton, Jiang, Wu, Jiménez-Rosales, Alejandra, Johnson, Michael D., Jorstad, Svetlana, Jones, Adam C., Joshi, Abhishek V., Jung, Taehyun, Karuppusamy, Ramesh, Kawashima, Tomohisa, Kettenis, Mark, Kim, Dong-Jin, Kim, Jae-Young, Kim, Jongsoo, Kim, Junhan, Kino, Motoki, Kocherlakota, Prashant, Kofuji, Yutaro, Koch, Patrick M., Koyama, Shoko, Kramer, Carsten, Kramer, Joana A., Kramer, Michael, Kubo, Derek, Kuo, Cheng-Yu, La Bella, Noemi, Lee, Sang-Sung, Levis, Aviad, Li, Zhiyuan, Lico, Rocco, Lindahl, Greg, Lindqvist, Michael, Lisakov, Mikhail, Liu, Jun, Liu, Kuo, Liuzzo, Elisabetta, Lobanov, Andrei P., Loinard, Laurent, Lonsdale, Colin J., Lowitz, Amy E., Lu, Ru-Sen, MacDonald, Nicholas R., Mahieu, Sylvain, Maier, Doris, Mao, Jirong, Marchili, Nicola, Markoff, Sera, Marrone, Daniel P., Marscher, Alan P., Martí-Vidal, Iván, Medeiros, Lia, Menten, Karl M., Mizuno, Izumi, Mizuno, Yosuke, Montgomery, Joshua, Moriyama, Kotaro, Moscibrodzka, Monika, Mulaudzi, Wanga, Müller, Cornelia, Müller, Hendrik, Mus, Alejandro, Musoke, Gibwa, Myserlis, Ioannis, Nagai, Hiroshi, Nagar, Neil M., Nakamura, Masanori, Narayanan, Gopal, Natarajan, Iniyan, Nathanail, Antonios, Fuentes, Santiago Navarro, Neilsen, Joey, Ni, Chunchong, Nowak, Michael A., Oh, Junghwan, Okino, Hiroki, Sánchez, Héctor Raúl Olivares, Oyama, Tomoaki, Özel, Feryal, Palumbo, Daniel C. M., Paraschos, Georgios Filippos, Park, Jongho, Parsons, Harriet, Pen, Ue-Li, Piétu, Vincent, PopStefanija, Aleksandar, Porth, Oliver, Prather, Ben, Principe, Giacomo, Psaltis, Dimitrios, Pu, Hung-Yi, Raffin, Philippe A., Rao, Ramprasad, Rawlings, Mark G., Ricarte, Angelo, Ripperda, Bart, Roelofs, Freek, Romero-Cañizales, Cristina, Ros, Eduardo, Roshanineshat, Arash, Ruiz, Ignacio, Ruszczyk, Chet, Rygl, Kazi L. J., Sánchez-Argüelles, David, Sánchez-Portal, Miguel, Sasada, Mahito, Satapathy, Kaushik, Savolainen, Tuomas, Schloerb, F. Peter, Schonfeld, Jonathan, Schuster, Karl-Friedrich, Shao, Lijing, Shen, Zhiqiang, Small, Des, Sohn, Bong Won, SooHoo, Jason, Salas, León David Sosapanta, Souccar, Kamal, Srinivasan, Ranjani, Stanway, Joshua S., Sun, He, Tazaki, Fumie, Tetarenko, Alexandra J., Tiede, Paul, Toma, Kenji, Toscano, Teresa, Traianou, Efthalia, Trent, Tyler, Trippe, Sascha, Turk, Matthew, van Bemmel, Ilse, van Langevelde, Huib Jan, van Rossum, Daniel R., Vos, Jesse, Ward-Thompson, Derek, Wardle, John, Washington, Jasmin E., Wharton, Robert, Wiik, Kaj, Witzel, Gunther, Wondrak, Michael F., Wong, George N., Wu, Qingwen, Yadlapalli, Nitika, Yamaguchi, Paul, Yfantis, Aristomenis, Yoon, Doosoo, Younsi, Ziri, Yu, Wei, Yuan, Feng, Yuan, Ye-Fei, Zensus, J. Anton, Zhang, Shuo, Zhao, Guang-Yao, and Zhao, Shan-Shan

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

The first very long baseline interferometry (VLBI) detections at 870$\mu$m wavelength (345$\,$GHz frequency) are reported, achieving the highest diffraction-limited angular resolution yet obtained from the surface of the Earth, and the highest-frequency example of the VLBI technique to date. These include strong detections for multiple sources observed on inter-continental baselines between telescopes in Chile, Hawaii, and Spain, obtained during observations in October 2018. The longest-baseline detections approach 11$\,$G$\lambda$ corresponding to an angular resolution, or fringe spacing, of 19$\mu$as. The Allan deviation of the visibility phase at 870$\mu$m is comparable to that at 1.3$\,$mm on the relevant integration time scales between 2 and 100$\,$s. The detections confirm that the sensitivity and signal chain stability of stations in the Event Horizon Telescope (EHT) array are suitable for VLBI observations at 870$\mu$m. Operation at this short wavelength, combined with anticipated enhancements of the EHT, will lead to a unique high angular resolution instrument for black hole studies, capable of resolving the event horizons of supermassive black holes in both space and time., Comment: Corresponding author: S. Doeleman

Published
2024
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40. First experimental study of multiple orientation muon tomography, with image optimization in sparse data environments

Author

Valencia, Jesus J., Hecht, Adam A., Morris, C. L., Guardincerri, E., Poulson, D., Bacon, J., and Durham, J. M.

Subjects
Electrical Engineering and Systems Science - Image and Video Processing, Nuclear Experiment, Physics - Applied Physics
Abstract

Due to the high penetrating power of cosmic ray muons, they can be used to probe very thick and dense objects. As charged particles, they can be tracked by ionization detectors, determining the position and direction of the muons. With detectors on either side of an object, particle direction changes can be used to extract scattering information within an object. This can be used to produce a scattering intensity image within the object related to density and atomic number. Such imaging is typically performed with a single detector-object orientation, taking advantage of the more intense downward flux of muons, producing planar imaging with some depth-of-field information in the third dimension. Several simulation studies have been published with multi-orientation tomography, which can form a three-dimensional representation faster than a single orientation view. In this work we present the first experimental multiple orientation muon tomography study. Experimental muon-scatter based tomography was performed using a concrete filled steel drum with several different metal wedges inside, between detector planes. Data was collected from different detector-object orientations by rotating the steel drum. The data collected from each orientation were then combined using two different tomographic methods. Results showed that using a combination of multiple depth-of-field reconstructions, rather than a traditional inverse Radon transform approach used for CT, resulted in more useful images for sparser data. As cosmic ray muon flux imaging is rate limited, the imaging techniques were compared for sparse data. Using the combined depth-of-field reconstruction technique, fewer detector-object orientations were needed to reconstruct images that could be used to differentiate the metal wedge compositions.

Published
2024

41. Individually Addressable Nanoscale OLEDs

Author

Zhang, Cheng, Ewald, Björn, Siebigs, Leo, Steinbrecher, Luca, Rödel, Maximilian, Emmerling, Monika, Pflaum, Jens, and Hecht, Bert

Subjects
Physics - Optics, Condensed Matter - Materials Science
Abstract

Augmented Reality (AR) and Virtual Reality (VR), require miniaturized displays with ultrahigh pixel densities. Here, we demonstrate an individually addressable subwavelength OLED pixel based on a nanoscale electrode capable of supporting plasmonic modes. Our approach is based on the notion that when scaling down pixel size, the 2D planar geometry of conventional organic light-emitting diodes (OLEDs) evolves into a significantly more complex 3D geometry governed by sharp nanoelectrode contours. These cause (i) spatially imbalanced charge carrier transport and recombination, resulting in a low quantum efficiency, and (ii) filament growth, leading to rapid device failure. Here, we circumvent such effects by selectively covering sharp electrode contours with an insulating layer, while utilizing a nano-aperture in flat areas of the electrode. We thereby ensure controlled charge carrier injection and recombination at the nanoscale and suppress filament growth. As a proof of principle, we first demonstrate stable and efficient hole injection from Au nanoelectrodes in hole-only devices with above 90 % pixel yield and longtime operation stability and then a complete vertical OLED pixel with an individually addressable nanoelectrode (300 x 300 nm$^{2}$), highlighting the potential to further leverage plasmonic nanoantenna effects to enhance the performance and functionality of nano-OLEDs.

Published
2024

42. SPRING: an effective and reliable framework for image reconstruction in single-particle Coherent Diffraction Imaging

Author

Colombo, Alessandro, Sauppe, Mario, Haddad, Andre Al, Ayyer, Kartik, Babayan, Morsal, Boll, Rebecca, Dagar, Ritika, Dold, Simon, Fennel, Thomas, Hecht, Linos, Knopp, Gregor, Kolatzki, Katharina, Langbehn, Bruno, Maia, Filipe, Mall, Abhishek, Mazumder, Parichita, Mazza, Tommaso, Ovcharenko, Yevheniy, Polat, Ihsan Caner, Schäfer-Zimmermann, Julian C., Schnorr, Kirsten, Schubert, Marie Louise, Sehati, Arezu, Sellberg, Jonas A., Senfftleben, Björn, Shen, Zhou, Sun, Zhibin, Svensson, Pamela, Tümmler, Paul, Usenko, Sergey, Ussling, Carl Frederic, Veteläinen, Onni, Wächter, Simon, Walsh, Noelle, Weitnauer, Alex V., You, Tong, Zuod, Maha, Meyer, Michael, Bostedt, Christoph, Galli, Davide Emilio, Patanen, Minna, and Rupp, Daniela

Subjects
Physics - Optics, Condensed Matter - Mesoscale and Nanoscale Physics, Physics - Atomic and Molecular Clusters, Physics - Computational Physics, Physics - Data Analysis, Statistics and Probability
Abstract

Coherent Diffraction Imaging (CDI) is an experimental technique to gain images of isolated structures by recording the light scattered off the sample. In principle, the sample density can be recovered from the scattered light field through a straightforward Fourier Transform operation. However, only the amplitude of the field is recorded, while the phase is lost during the measurement process and has to be retrieved by means of suitable, well-established, phase retrieval algorithms. In this work we present SPRING, an analysis framework tailored on X-ray Free Electron Laser (XFEL) diffraction data that implements the Memetic Phase Retrieval method to mitigate the shortcomings of conventional algorithms. We benchmark the approach on experimental data acquired in two experimental campaigns at SwissFEL and European XFEL. Imaging results on isolated nanostructures reveal unprecedented stability and resilience of the algorithm's behavior on the input parameters, as well as the capability of identifying the solution in conditions hardly treatable so far with conventional methods. A user-friendly implementation of SPRING is released as open-source software, aiming at being a reference tool for the coherent diffraction imaging community at XFEL and synchrotron facilities., Comment: 30 pages, 13 figures. Authors list updated

Published
2024

43. Beating the Ramsey limit on sensing with deterministic qubit control

Author

Hecht, M. O., Saurav, Kumar, Vlachos, Evangelos, Lidar, Daniel A., and Levenson-Falk, Eli M.

Subjects
Quantum Physics
Abstract

Quantum sensors promise revolutionary advances in medical imaging, energy production, mass detection, geodesy, foundational physics research, and a host of other fields. In many sensors, the signal takes the form of a changing qubit frequency, which is detected with an interference measurement. Unfortunately, environmental noise decoheres the qubit state, reducing signal-to-noise ratio (SNR). Here we introduce a protocol for enhancing the sensitivity of a measurement of a qubit's frequency in the presence of decoherence. We use a continuous drive to stabilize one component of the qubit's Bloch vector, enhancing the effect of a small static frequency shift. We demonstrate our protocol on a superconducting qubit, enhancing SNR per measurement shot by 1.65$\times$ and SNR per qubit evolution time by 1.09$\times$ compared to standard Ramsey interferometry. We explore the protocol theoretically and numerically, finding maximum enhancements of 1.96$\times$ and 1.18$\times$, respectively. We also show that the protocol is robust to parameter miscalibrations. Our protocol provides an unconditional enhancement in signal-to-noise ratio compared to standard Ramsey interferometry. It requires no feedback and no extra control or measurement resources, and can be immediately applied in a wide variety of quantum computing and quantum sensor technologies to enhance their sensitivities.

Published
2024

44. Hybrid Surrogate Models: Circumventing Gibbs Phenomenon for Partial Differential Equations with Finite Shock-Type Discontinuities

Author

Cardona, Juan-Esteban Suarez, Reddy, Shashank, and Hecht, Michael

Subjects
Mathematics - Numerical Analysis
Abstract

We introduce the concept of Hybrid Surrogate Models (HSMs) -- combining multivariate polynomials with Heavyside functions -- as approximates of functions with finitely many jump discontinuities. We exploit the HSMs for formulating a variational optimization approach, solving non-regular partial differential equations (PDEs) with non-continuous shock-type solutions. The HSM technique simultaneously obtains a parametrization of the position and the height of the shocks as well as the solution of the PDE. We show that the HSM technique circumvents the notorious Gibbs phenomenon, which limits the accuracy that classic numerical methods reach. Numerical experiments, addressing linear and non-linearly propagating shocks, demonstrate the strong approximation power of the HSM technique.

Published
2024

45. Higher TIER bumble bees and solitary bees recommendations for a semi-field experimental design

Author

Allan, Matthew J., Alscher, Annika, Amsel, Kristin, Classen, Christian, Cornement, Magdaléna, Elston, Charlotte, Exeler, Nina, Franke, Lea, Frommberger, Malte, Giffard, Hervé, Guerola, Juan Sorlí, Hecht-Rost, Sabine, Hodapp, Bettina, Hotopp, Ines, Jenkins, Carole, Jütte, Tobias, Kimmel, Stefan, Klein, Olaf, Kullmann, Britta, Lückmann, Johannes, Persigehl, Markus, Roessink, Ivo, Schneider, Christof, Schnurr, Alexander, Tänzler, Verena, and van der Steen, Jozef J.M.

Subjects
semi-field testing, non-apis bees, bumble bees, solitary bees, Agriculture, Botany, QK1-989
Abstract

The publication of the proposed EFSA risk assessment guidance document of plant protection products for pollinators highlighted that there are no study designs for non-Apis pollinators available. Since no official guidelines exist for semi-field testing at present, protocols were proposed by the ICPPR non-Apis working group and two years of ring-testing were conducted in 2016 and 2017 to develop a general test set-up. The ringtest design was based on the draft EFSA guidance document, OEPP/EPPO Guideline No. 170 and results of discussions regarding testing solitary bees and bumble bees during the meetings of the ICPPR non-Apis workgroup. Ring-tests were conducted with two different test organisms, one representative of a social bumble bee species (Bombus terrestris L; Hymenoptera, Apidae) and one representative of a solitary bee species (Osmia bicornis L; Hymenoptera, Megachilidae). The species are common species in Europe, commercially available and widely used for pollination services. Several laboratories participated in the higher-tier ring tests. 15 semi-field tests were conducted with bumble bees and 16 semi-field tests were done with solitary bees in 2016 and 2017. Two treatment groups were always included in the ringtests: an untreated control (water treated) and the treatment with dimethoate as a toxic reference item (optional other i.e. brood-affecting substances fenoxycarb or diflubenzuron). The toxic reference items were chosen based on their mode of action and long term experience in honey bee testing. A summary of the ringtest results will be given and the recommendations for the two semi-field test designs will be presented.

Published
2020
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46. Mono-crystalline gold platelets: a high-quality platform for surface plasmon polaritons

Author

Kaltenecker Korbinian J., Krauss Enno, Casses Laura, Geisler Mathias, Hecht Bert, Mortensen N. Asger, Jepsen Peter Uhd, and Stenger Nicolas

Subjects
mono-crystalline gold, near-field imaging, plasmonics, Physics, QC1-999
Abstract

We use mono-crystalline gold platelets with ultra-smooth surfaces and superior plasmonic properties to investigate the formation of interference patterns caused by surface plasmon polaritons (SPPs) with scattering-type scanning near-field microscopy at 521 and 633 nm. By applying a Fourier analysis approach, we can identify and separate several signal channels related to SPPs launched and scattered by the atomic force microscopy tip and the edges of the platelet. Especially at the excitation wavelength of 633 nm, we can isolate a region in the center of the platelets where we find only contributions of SPPs which are launched by the tip and reflected at the edges. These signatures are used to determine the SPP wavelength of λSPP = 606 nm in good agreement with theoretical predictions. Furthermore, we were still able to measure SPP signals after 20 µm propagation, which demonstrates impressively the superior plasmonic quality of these mono-crystalline gold platelets.

Published
2020
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