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2022 JUL 23 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on aneurysm have been published. According to news reporting [...]

2020 OCT 31 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on bioprosthetics are discussed in a new report. According to [...]

2020 AUG 1 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on Enzymes and Coenzymes - Mixed Function Oxygenases have [...]

2019 AUG 17 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on Drugs and Therapies - Physiology and Pharmacology. [...]

2019 JUL 13 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Data detailed on Health and Medicine - Cardiology have been presented. According [...]

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jtcvs.2009.06.025 Byline: Hans-Joachim Schafers (a), Frank Langer (a), Petra Glombitza (a), Takashi Kunihara (a), Roland Fries (b), Diana Aicher (a) Abbreviations: AR, aortic regurgitation; PTFE, polytetrafluoroethylene Abstract: Aortic valve repair is a more recent approach for the treatment of aortic regurgitation. Limited data exist for reconstruction in specific pathologies with isolated cusp pathology. We analyzed the results of aortic valve repair in patients with aortic regurgitation caused by myxomatous cusp prolapse in the presence of tricuspid valve anatomy and normal root size. Author Affiliation: (a) Department of Thoracic and Cardiovascular Surgery, University Hospitals of Saarland, Homburg/Saar, Germany (b) Gotthard-Schettler-Klinik, Bad Schonborn, Germany Article History: Received 25 December 2008; Revised 26 March 2009; Accepted 23 June 2009 Article Note: (footnote) Disclosures: Name.

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jtcvs.2009.05.024 Byline: Emmanuel Lansac (a)(b), Isabelle Di Centa (c), Francois Raoux (d), Neil Bulman-Fleming (e), Adrian Ranga (e), Aicha Abed (a)(f), Maguette Ba (a), Anthony Paolitto (e), Didier Letourneur (a)(f), Anne Meddahi-Pelle (a)(g) Abbreviations: AI, aortic insufficiency; SEM, scanning electron microscopy; STJ, sinotubular junction Abstract: Dystrophic aortic insufficiency is characterized by dilation of the aortic annular base and sinotubular junction diameters preventing coaptation of thin and pliable cusps amenable to valve repair. An expansible aortic ring was designed to reduce dilated aortic root diameters to increase valvular coaptation height while maintaining root dynamics. The properties of the device were tested in vitro and in vivo in an ovine model. Author Affiliation: (a) INSERM, U 698, Cardiovascular Bioengineering, Bichat University Hospital, Paris, France (b) Cardiovascular Surgery, Foch Hospital, Suresnes, France (c) Vascular Surgery, Ambroise Pare University Hospital, Boulogne-Billancourt, France (d) Cardiology, Marie Lannelongue Hospital, Le Plessis Robinson, France (e) CORONEO, Inc, Montreal, Quebec, Canada (f) Institut Galilee, University Paris 13, Villetaneuse, France (g) University of Orleans, Orleans, France Article History: Received 23 February 2009; Revised 13 April 2009; Accepted 17 May 2009 Article Note: (footnote) E. Lansac is the recipient of a 'poste d'accueil INSERM.' A. Abed was supported by the Agence of Biomedecine. The study was supported by CORONEO, Inc; INSERM; University Paris 13; and Assistance Publique des HA[acute accent]pitaux de Paris., Disclosures: Drs Lansac and Di Centa have Consultant Agreements with the company CORONEO, Inc.

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jtcvs.2008.05.059 Byline: Andrew E. Newcomb, Tirone E. David, Vidyadhar S. Lad, Jerzy Bobiarski, Susan Armstrong, Manjula Maganti Abbreviations: ePTFE, expanded polytetrafluoroethylene; MR, mitral regurgitation; TEE, transesophageal echocardiography Abstract: This study examines the outcomes of mitral valve repair in a defined group of patients with mitral regurgitation caused by advanced myxomatous degeneration. Author Affiliation: Division of Cardiovascular Surgery of the Peter Munk Cardiac Centre at the Toronto General Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada Article History: Received 29 February 2008; Revised 4 May 2008; Accepted 20 May 2008

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jtcvs.2007.11.072 Byline: Claudio F. Russo (a), Aldo Cannata (a), Marco Lanfranconi (a), Ettore Vitali (a), Andrea Garatti (a), Edgardo Bonacina (b) Abbreviations: AWS, aortic wall score; BAV, bicuspid aortic valve Abstract: Patients with bicuspid aortic valve are at increased risk for aortic complications. Author Affiliation: (a) Angelo De Gasperis Department of Cardiac Surgery, Niguarda Ca Granda Hospital, Piazza Ospedale Maggiore, Milan, Italy (b) Pathology Department, Niguarda Ca Granda Hospital, Piazza Ospedale Maggiore, Milan, Italy Article History: Received 10 July 2007; Revised 13 November 2007; Accepted 26 November 2007

2017 JUL 29 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators discuss new findings in Heart Valves. According to news reporting originating [...]

Systolic and diastolic function were assessed at preoperative cardiac catheterization in 6 patients with classic tricuspid atresia and were compared with those in control subjects. All patients had systemic-to-pulmonary shunts. Left ventricular end-systolic and end-diastolic volumes and masses were significantly larger in the patient group; stroke volume and the ratio of volume to mass were also higher, but not significantly. Mean end-diastolic, peak systolic and end-systolic pressures were similar. Mean stress and end-systole and peak systole were significantly higher in the patient group. Operant chamber stiffness tended to be lower than normal, but was not statistically significant, and myocardial stiffness was normal for the patient group also. Indexes of systolic function were compared. The rate-corrected mean velocity of fiber shortening in the patient group was lower and its relation with stress at end-systole was variable with 4 abnormal patients. The ratio of stress and end-systole/end-systolic volume was significantly lower in patients. The duration of hospital stay did not correlate with end-diastolic volume or any parameter. Thus, this study found abnormalities of load-dependent and independent indexes of systolic function with normal diastolic function in young preoperative patients with tricuspid atresia. (Am J Cardiol 1994;73:292-297)

Forty-seven consecutive patients (mean age 61 [+ or -] 8 years) referred for cardiac catheterization due to moderate to severe aortic (n = 30) or mitral (n = 17) valvular heart disease were examined by technetium-99m isonitrile tomography together with a high-dose dipyridamole infusion (0.7 mg/kg) and handgrip stress. Tomography did not identity coronary artery disease (CAD) in 3 of the 21 patients with angiographically proven disease (sensitivity 86%) and suggested false positive results in 5 of the 26 without the disease (specificity 81% and negative predictive accuracy 88%). No patient without angina pectoris and with negative scintigraphy (n = 14) had angiographically significant ([is greater than 50% diameter stenosis) CAD. Overall vessel sensitivity was 63%, and specificity was 92%. The frequency of side effects during the dipyridamole-handgrip test was only 7%. No serious complications occurred during stress tests. Thus, technetium-99m isonitrile tomographic imaging, together with high-dose dipyridamole and handgrip exercise, is a useful noninvasive method in excluding significant CAD in patients with valvular heart disease.