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Bedeutende Persönlichkeiten, deren Namen für entscheidende Neuerungen in der Kinderherzchirurgie und Kinderkardiologie stehen, werden im Sinne eines'historischen Feuilletons'vorgestellt und charakterisiert, ihr Werk wird in den jeweiligen historischen, geistes- und wissenschaftsgeschichtlichen Kontext gestellt. Ein Blick in die spannende Entwicklung der Fachgebiete, der zugleich die Voraussetzungen für zukünftige Ideen und Problemlösungen aufzeigt.

​The second edition of this book explores different aspects of the relationship between hypertension and brain damage, providing readers with up-to-date information that will be of interest to clinicians and researchers alike. In recent years, numerous studies have been published that have added new evidence on different aspects of the disease. New recommendations and the latest hypertension guidelines on stroke and dementia will be described in this edition, which will include not only updated content but also new chapters on aspects that have recently emerged in relation to hypertension and brain damage. After an introductory chapter on the epidemiology and burden of neurological disease induced by hypertension, the significance of various comorbidities that represent risk factors for brain damage in the context of hypertension is discussed. The effects of hypertension on small and large cerebral arteries and the consequences on brain damage are then examined in detail. Similarly, the association between hypertension and ischaemic stroke, transient ischaemic attack and haemorrhagic stroke is explored in depth, and the evidence and guidelines for reducing hypertension during the acute phase of each form of stroke are summarised. Both primary and secondary prevention of stroke are addressed, with the results of major studies presented. The reader will also find interesting new perspectives on the role of different imaging techniques, including CT and functional MRI, in detecting and diagnosing brain damage in patients with hypertension. The concluding chapters examine the relationship between hypertension and cognitive decline and dementia associated with hypertension, its pathophysiology, the detection of cognitive impairment in daily practice, and its prevention and treatment.

Double-outlet right ventricle (DORV) represents a great challenge for cardiac surgeons due to the absence of standard surgical approach and this book is the first complete manual detailing decision-making in all anatomical types of DORV: subaortic, subpulmonary, subarterial and noncommitted defects. It provides information regarding the molecular mechanisms and clinical consequences of the most important syndromes in patients with cyanotic congenital heart defects, arterial hypoxemia and myocardial remodeling.Double-Outlet Right Ventricle explains the most important operations using real anatomical specimens. This helps readers to understand these surgical principles from a surgeon's perspective. All operations are described according to indication, timing, intracardiac revision (structures that should be accessed during an operation), surgical technique, advantages and disadvantages. The book is therefore of importance to all cardiac surgeons and healthcare professionals working with this group of patients.

This case-based atlas encompasses all aspects of imaging in congenital cardiac defects, cardiac masses, inflammatory and acquired heart diseases, cardiomyopathies and coronary-related pathologies. The chapters begin with a description of the imaging approach, followed by cases comprehensively covering the gamut of clinical scenarios that may be encountered in clinical practice. The atlas provides pertinent information about each discussed disease state, its imaging diagnosis and recent advances, including role of radiology in management, follow up and prognostication. Cases that may pose as imaging differentials accompany the index case, followed by a variety of companion cases illustrating the possible spectrum of abnormalities that the reader may be confronted with while dealing with the index case. It acts as a guide for the cardiovascular radiologist, physician, paediatrician, internist, cardiologist, cardiothoracic surgeon as well as radiology residents for inculcating an evidence-based approach for choosing the right imaging algorithm in the given clinical situation. The highly visual design of the atlas enables it to act as a quick and ready reference.

In der 4., durchgehend aktualisierten Auflage behält der'Leitfaden Herztransplantation'die interdisziplinäre Ausrichtung und die praxisorientierte Darstellung bei. Das Buch wendet sich an Leserinnen und Leser aus dem ärztlichen Bereich, Pflege und Physiotherapie, mit den Informationen zur Betreuung vor und nach dem Eingriff und Empfehlungen für das Alltagsleben der Transplantierten sind besonders auch niedergelassene Ärztinnen und Ärzte angesprochen. Dabei trägt die Neuauflage der veränderten klinischen Situation Rechnung, die durch die Entwicklungen der letzten Jahre bei der Anwendung der Kreislauf-Unterstützungssysteme und den Mangel an Spenderorganen geprägt ist.

This two-volume manual covers the most relevant protocols in pediatric cardiac care to serve as a practical guide that matches and reflects the high level of accumulated knowledge and expertise in this clinical field. It includes 179 chapters and offers comprehensive, precise, and up-to-date practical tips with specific care protocols to provide the most efficient strategies for high-quality care in patients with congenital heart disease (CHD). This book simplifies learning with many tables, flowcharts, graphs, and algorithms for easy access and fast action. Volume II covers many vital sections, such as ethical considerations in pediatric cardiac patients, pediatric cardiac surgery, pediatric cardiac intensive care unit (PCICU) guidelines, clinical pharmacy guidelines, adults with congenital heart disease, appendix (with normal values/reference tables/graphs/scores and various calculated indexes used and needed for proper pediatric cardiac care).This manual is a must-have resource for pediatricians, neonatologists, clinical pharmacy specialists, pediatric intensive care physicians, pediatric cardiologists, pediatric cardiac intensive care physicians, pediatric cardiac surgeons, and/or surgeons interested in pediatric cardiac surgery.

This two-volume manual covers the most relevant protocols in pediatric cardiac care to serve as a practical guide that matches and reflects the high level of accumulated knowledge and expertise in this clinical field. It includes 179 chapters and offers comprehensive, precise, and up-to-date practical tips with specific care protocols to provide the most efficient strategies for high-quality care in patients with congenital heart disease (CHD). This book simplifies learning with many tables, flowcharts, graphs, and algorithms for easy access and fast action. Volume I covers many key sections, such as prenatal morphogenesis and physiology of the human heart, fetal cardiology, neonates and congenital heart disease, cardiac imaging, pediatric cardiac catheterization, pediatric cardiac electrophysiology, critical events and emergency procedures in pediatric cardiac care, management of specific cardiac conditions, general pediatric and subspecialty issues related to children with CHD, follow-up standards in pediatric outpatient cardiology clinic, prophylaxis in children with CHD, quality aspects, professional conduct and training in pediatric cardiac care. This manual is a must-have resource for pediatricians, neonatologists, clinical pharmacy specialists, pediatric intensive care physicians, pediatric cardiologists, pediatric cardiac intensive care physicians, pediatric cardiac surgeons, and/or surgeons interested in pediatric cardiac surgery.

This book describes the different aspects of ischemic heart disease, one of the leading causes of death in industrialized countries, and whose growing prevalence represents a major challenge in terms of short- and long-term management and surveillance. This volume offers a comprehensive discussion of the state-of-the-art diagnostic imaging options, of disease risk stratification, selection of candidates for surgical intervention, percutaneous revascularitation, mechanical assist devices implantation. Recently, the morbidity and mortality of ischaemic heart disease have substantially improved because of the progress in therapeutic strategies, represented by the dramatic evolution of percutaneous coronary interventions, that are carefully described in the volume, together with all the other most recent treatment options: from medical therapy to conventional surgery, minimally invasive surgery, surgery of ischemic complications. The biggest challengein the next years is, however, to reduce the incidence of coronary artery disease worldwide.This highly illustrated, case oriented reference book is aimed at cardiology fellows in training, while also helpful to surgeons, cardiologists, imaging specialists, interventional cardiologists, as well as other clinicians and students involved in the diagnosis and treatment of ischemic disease.

Dieses Buch bietet neue Einblicke in die Pathogenese der Atherosklerose. Die Kapitel befassen sich mit den Risikofaktoren für Atherosklerose, den Auswirkungen von Wachstum und Alterung auf die Gefäßarchitektur und der entscheidenden Rolle, die das Mikrogefäßsystem bei der Entstehung von Atherosklerose spielt. Eine mikrovaskuläre Dysfunktion würde erklären, warum die bekannten Risikofaktoren das Risiko für den Einzelnen tatsächlich erhöhen. Dieser Pathomechanismus würde nicht nur für die obstruktive Atherombildung gelten, sondern auch für die aneurysmatische Dilatation sowie für die Dissektion der Aorta und der peripheren Arterien. Durch diese Brille betrachtet, ergeben sich neue präventive und therapeutische Möglichkeiten.In Atherosclerosis Pathogenesis and Microvascular Dysfunction wird ein einheitlicher Mechanismus für die Entstehung von Atherosklerose vorgeschlagen und es werden potenzielle präventive und therapeutische Möglichkeiten auf der Grundlage dieses Konzepts beschrieben. Das Buch stellt daher eine zeitgemäße und wertvolle Ressource für Ärzte der Inneren Medizin, Kardiologie, Angiologie, Herz- und Gefäßchirurgen, Pathologen, Forscher, Auszubildende und Studenten dar.

This book offers a historical account of the development of the On-X carbon mechanical heart valve, discussing the steps involved in developing the materials, and describes how the design of the valve has evolved over the years. It explores both the scientific and corporate problems researchers have encountered over the years in the journey of making a mechanical heart valve. The chapters provide a detailed description of the design of the mechanical leaflet-based prosthetic valve, with a particular focus on blood flow characteristics. This book includes an overview of the state-of-the-art in the chemistry and physics of carbon, and compiles the advances in carbon-based technology and its applications in cardiac and thoracic surgery.This is an ideal book for bioengineers working on the chemistry and physics of carbon, and other professionals involved with cardiac and thoracic surgery.

This book provides comprehensive information and clarity on all aspects of diagnosing and managing constrictive pericarditis. The operative procedures for constrictive pericarditis are presented in detail with technical tips supplemented by surgical videos. Further, it explores and guides on issues with mixed opinions like the role of corticosteroids, timing of the operation, choice of the operative procedure, terminologies to describe the extent of decortication, and the requirement of cardiopulmonary bypass. Despite experience spanning over 100 years, there is no fool-proof formula in the published literature that can be used in selecting an optimal surgical approach for a given patient. The terms'radical','total','extensive','complete','subtotal','adequate','near-total'and'partial'pericardiectomy also have been variably used in the literature, often without a precise definition of the limits of pericardial resection.Providing an update on the latest advancements and long-term results of pericardiectomy appeals to all clinicians managing constrictive pericarditis. For the trainees, it offers insights into surgical techniques'relevant anatomy and foundation. The book will be beneficial to MBBS, MD, MS, M.Ch (CTVS), DM (Cardiology), Diplomate of National Board (Cardiology and CTVS), FRCS, FRACS, MD (USA, Canada, and in all developing and developed countries).

This book should represent a guideline for launching an extracorporeal membrane oxygenation (ECMO) program. It describes in detail particularities and special features of planning, setting up, developing, structuring and maintaining of ECMO support program for instable patients with the need of transportation from peripheral hospitals to an experienced ECMO centre for further treatment.Authors have condensed both the current evidence and Guidelines on ECMO and eCPR support and have highlighted in detail the issue of planning, setting up, developing, structuring and maintaining this program with the view to helping other centres launching this life-saving service taking into account their experience in this important field of medicine. In this context, the main benefit of this book is the outstanding and particular aim to educate the reader in developing and maintaining a large-spectrum ECMO program. The volume, richly illustrated and written by KOLs using an expository writing style to promote the readability will appeal to intensivists, anesthesiologists and cardiologists as well as cardiac- and thoracic-surgeons and pneumologists

This text and guide discusses the surgical and medical management of congenital heart diseases in both adult and children. It describes the disease, pathology, treatment, complications and follow-up with extensive use of didactic material to educate the reader to the practicalities of the subject. It details the novel research via an extensive literature review, while covering all aspects of the surgical and medical treatment of congenital heart disease. It includes review of the laparoscopic techniques and epidemiology of each disease involved and their prevalence to provide the reader with the full clinical picture.Clinical and Surgical Aspects of Congenital Heart Diseases: Text and Study Guide provides a thorough practical reference for the discipline with the use of illustrations and charts to facilitate understanding. It is essential reading for all trainee and practicing cardiac surgeons, cardiologists and internists, and all interested healthcare professionals.

This book provides a guide to the surgical techniques required in thoracic surgery. Minimally invasive surgery (MIS) has become a standard surgical technique in the field of thoracic surgery recently. In addition, the evolution of video equipment and surgical instruments, and robotic devices lead to the rapid development of surgical techniques. Providing the latest and detailed surgical techniques and reviews of video-assisted thoracic surgery and robotic surgery in commonly performed thoracic surgery, and is expected to be of great help to general, thoracic, cardiothoracic, and cardiovascular surgeon who starts minimally invasive surgery.

The book covers 75 autopsy-based cases (about 75) of common and uncommon presentations of various cardiovascular diseases (CVDs). It emphasizes the importance of the autopsies, which have played a pivotal role in the understanding of the pathology and hence the clinical manifestations of several CVDs. The book attempts to present the material from the perspective of the autopsy table. It uses the clinical data as the initial framework and the autopsy findings to develop a true understanding of the disease and the associated pathophysiology of the condition with final clinico-pathological correlation. Each case covers a complete journey of the deceased patient concisely under the following headings—title, clinical history, autopsy findings and discussion, which includes a brief review of the literature. The text is accompanied by relevant high-quality macroscopic and microscopic images. The book is relevant for specialists in pathology, cardiology, cardiac surgery, internal medicine, critical care and pediatrics

This extensively revised textbook reviews the use of transesophageal echocardiography (TEE) in pediatric and young adult patients with cardiac disease. It reviews how TEE has made a vital contribution to these patients'successful and continually improving clinical outcomes, enabling them to live well into adulthood. The book details the evolving technology and applications of TEE (including three-dimensional TEE), describing how this imaging approach remains at the forefront of clinical practice for pediatric patients and those with congenital heart disease (CHD). Transesophageal Echocardiography for Pediatric and Congenital Heart Disease represents a unique contribution as the only contemporary text to focus exclusively on the clinical application of TEE in children and all patients with CHD. Written by numerous prominent specialists in the field, it presents a comprehensive, modern and integrated review of the subject. Specific chapter topics include the physicsand instrumentation of TEE, structural and functional evaluation, and specialized aspects of the examination, with emphasis on the technical considerations pertinent to both pediatric and adult patients with a variety of congenital and acquired cardiovascular pathologies. Consequently, it serves as a comprehensive reference for the TEE evaluation of CHD, utilizing the segmental approach to diagnosis and discussing the TEE evaluation of the many anomalies encompassing the CHD spectrum. In addition, numerous other relevant topics are discussed, including application of TEE for perioperative and interventional settings. The book is richly illustrated, with many chapters supplemented by illustrative case studies and accompanying videos. A specific section with multiple-choice questions and answers is provided at the end of each chapter to reinforce key concepts. This textbook therefore provides an invaluable and indispensable resource for all trainees and practitioners using TEE in the management of CHD and pediatric patients.

This book provides a focused resource on how cardiac surgery capacity can be developed and how it assists in the sustainable development and strengthening of associated health systems. Background is provided on the extent of the problems that are experienced in many nations with suggestions for how suitable frameworks can be developed to improve cardiac healthcare provision. Relevant aspects of governance, financial modelling and disease surveillance are all covered. Guidance is also given on how to found and nurture cardiac surgery curriculum and residency programs. Global Cardiac Surgery Capacity Development in Low and Middle Income Countries provides a practically applicable resource on how to treat cardiac patients with limited resources. It identifies the key challenges and presents strategies on how these can be managed, therefore making it a critical tool for those involved in this field.

This latest book in the Clinical Cases in Cardiology series presents a variety of commonly and rarely encountered cases associated with ​cardio-oncology. It explores the history of the discipline and each case described features concise practically orientated information on how to appropriately carry out physical examinations and utilize diagnostic tests including electrocardiography and monoclonal antibodies. Practically focused guidance is also provided on how to apply therapeutic techniques and the latest management strategies appropriately. Clinical Cases in Cardio-Oncology provides a concise practically applicable guide of how to diagnose and treat a range of conditions associated with ​cardio-oncology, making it a critical addition to the literature on the topic and a valuable resource for all medical practitioners who encounter these patients in their day-to-day practice.

Die Herzchirurgie nimmt einen festen Platz im Behandlungskonzept komplexer Herzerkrankungen ein. Zu den gegenwärtigen Herausforderungen des Fachgebietes gehören die Integration und Bewertung neuer chirurgischer und interventioneller Techniken, sowie der anhaltende Trend zu älteren und multimorbiden Patienten mit höherem Risikoprofil. Mehr denn je erfordern die hohe Patientensicherheit und guten Langzeitergebnisse eine enge interdisziplinäre Zusammenarbeit aller beteiligten Spezialisten.Dieses Kompendium bietet dem Leser eine schnell zugängliche Darstellung der wesentlichen Grundlagen, bewährten Standards und Entscheidungshilfen bei den häufigsten herzchirurgischen Eingriffen im Erwachsenenalter. Dafür wurden die entsprechenden Inhalte von erfahrenen Spezialisten in 20 Kapiteln bearbeitet. Sie umfassen neben allen wichtigen herzchirurgischen Operationen und Techniken auch Kenntnisse über radiologische Verfahren, Rhythmologie und Elektrophysiologie, Psychosomatik, New Technologies, Pulmonalembolie, Lebensqualität und Rehabilitation, Herzersatz und ventrikuläre Unterstützungssysteme sowie Hinweise zum besseren Verständnis von Fachliteratur. In überschaubarem Format und in prägnanter Darstellung lassen sich sämtliche Aspekte der Erwachsenenherzchirurgie auf dem gegenwärtigen Stand der Praxis rasch nachschlagen.Das Kompendium richtet sich an Herzchirurgen, sowie an Kardiologen, Anästhesisten, Radiologen, und an alle Fach- und Hausärzte, die Patienten mit Herzerkrankungen behandeln.

While there are many outstanding resources providing in-depth review of electrophysiology topics, this extensively updated book is one of the few case-based books that comprehensively cover clinical electrophysiology, devices and ablation. Case review offers a simple, yet effective way in teaching important concepts, offering insight into both the basic pathophysiology of a problem as well as the clinical reasoning that leads to a solution. As the field of cardiac electrophysiology evolves, the challenge remains to educate new generations of cardiac electrophysiologists with the basics as well as the latest advances in the field. Cardiac Electrophysiology: Clinical Case Review collates the most comprehensive case-based reviews of electrophysiology designed to appeal to all students of the field whether they are fellows, allied professionals or practicing electrophysiologists. The Editors have recruited some of the true experts in the field to contribute cases that they have encountered and summarizing the important learning objectives in a succinct way. Covering clinical electrophysiology, device troubleshooting and analysis as well as intracardiac electrogram analysis and ablation, readers will find the cases useful as a review of electrophysiology or in their day to day interactions with patients.

This engaging book covers a multitude of topics related to heart rhythm disorders (HRDs) and uniquely familiarizes readers with the development of treatment modalities over the past several decades, including the evolution of anti-arrhythmic drugs, pacemakers, defibrillators, and catheter ablation. Organized in ten sections, this title serves as both an archival and a contemporary resource for clinicians. The first section describes the discovery of the circulatory system by William Harvey in 1628 and outlines the development and understanding of HRD since the advent of intra-cardiac electrophysiology. Subsequent sections discuss the historical evolution of abnormal heart rhythms, such as supra and ventricular rhythms and sudden cardiac death, their treatment with drugs, surgery, pacemakers, implantable defibrillators and catheter ablation. Section nine offers a fascinating narration of the clinical evolution of overcoming heart attacks and its impact on HRDs. Thefinal section explores potential new frontiers in HRD and the factors that may contribute to the prospective rise of cardiovascular diseases. A ground-breaking and invaluable addition to the clinical literature, Heart Rhythm Disorders: History, Mechanisms and Management Perspectives details the pervasive nature of cardiovascular diseases in human history, their ramifications, and their projected effects on at-risk demographic populations and human health in general.

Zur Überbrückung eines akuten Kreislaufversagens wurden in den letzten Jahren unterschiedliche Unterstützungssysteme mit spezifischen Vorzügen und Nachteilen entwickelt. Das Prinzip, die Indikationen zur Anwendung und mögliche Risiken und Komplikationen aller angewandten Systeme (IABP, Impella, TandemHeart, Zentrifugalpumpen, va-ECMO) sind anschaulich und mit zahlreichen Abbildungen von Experten beschrieben. Grundlagenthemen wie die Pathophysiologie des Schocks und das Gerinnungsmanagement werden ebenso berücksichtigt wie spezielle Anwendungen bei Kindern oder für den Patiententransport.

This book provides new perspectives on the pathogenesis of atherosclerosis. Chapters cover atherosclerosis risk factors, the effect of growth and aging on vascular architecture, and the crucial role the microvasculature plays in atherosclerosis development. Microvascular dysfunction would explain why the well-known risk factors actually put individuals at higher risk. This pathomechanism would also hold true not only for obstructive atheroma formation but also for aneurysmal dilatation as well as for aortic and peripheral artery dissection. When seen through this lens, novel preventive and therapeutic opportunities can be envisioned.Atherosclerosis Pathogenesis and Microvascular Dysfunction proposes a single unifying mechanism of atherosclerosis development and describes potential preventative and therapeutic avenues based on this concept. It therefore represents a timely and valuable resource for internal medicine, cardiology, angiology cardiovascular surgeons, pathology clinicians, researchers, trainees, and students.

This book provides an easy-to-use guide, giving cardiologists and other physicians more confidence in training with and understanding cardiac magnetic resonance (CMR) in clinical daily practice. The case-based format promotes step-by-step learning and makes this book a helpful tool for students, residents and trainees in cardiology. An updated, comprehensive review of CMR diagnostic criteria is provided for all clinical cardiovascular applications of CMR in adult patients, from ischemic heart diseases to myocarditis, and from pericardial diseases to tumors, artifacts and incidental findings. CMR is an expanding imaging technique for cardiologists and radiologists alike. Despite several textbooks, manuals and dedicated texts, clinicians may still find it difficult to familiarize themselves with the exam and there are limited formats that provide easy access to the basic information (e.g. physics, specific applications) that are needed for training and clinical interpretation(especially case-based). By describing the basics of physics and methodology in a straightforward manner and providing meaningful clinical examples, this book will help all cardiologists dealing with cardiac imaging as well as doctors in training to quickly and accurately interpret CMR findings in their clinical practice.

This book shows how new technologies and technical skills together with deeper understanding of pathophysiology of visceral and renal ischemia have contributed to significant improvements in the clinical outcomes in patients undergoing complex aortic repair involving splanchnic arteries. In recent years, aortic repair has expanded its borders, focusing more and more on the particularly challenging segments from which critical branches originate. Optimal results in this area are obtained through a multidisciplinary approach based on crucial elements such as sophisticated imaging techniques, advanced anesthesiological and pharmacological strategies, as well as updated surgical techniques and devices able to reduce ischemic injuries. The book presents problems tackled from different perspectives, by analyzing the main technical aspects of the surgical technique but also functional and metabolic issues. It also discusses concepts such as ischemic preconditioning and ischemia-reperfusion mechanisms, as well as innovative investigational approaches. In the “endovascular era”, it highlights the most recent updates in complex endovascular repair involving renal and visceral arteries, providing both practical tips and tricks and outcomes analyses. The volume also addresses specific, rarely reported problems in vascular surgery, including issues in renal transplant, oncologic surgery with involvement of splanchnic arteries and of the vena cava, and use of the deep veins in aortic surgery. This volume represents a powerful tool for both young and experienced operators who wish to approach the complex aortic pathology either by open surgery or through endovascular methods.”

This book provides a multidisciplinary approach to the maintenance of hemostasis and minimisation of blood loss in patients undergoing cardiac surgery. All aspects of patient blood management are covered that may contribute to a reduction in perioperative bleeding and transfusion requirements in cardiac surgery. This is achieved through practical cases and a theoretical background that gives a better understanding of patient hemostasis and the occurrence of bleeding complications. This book is relevant to cardiac surgeons, anesthesiologists, clinical perfusionists, hematologists and intensivists.

The book discusses the application of evoked potentials recording in comatose patients admitted to Intensive Care Units and in patients undergoing surgical procedures that require direct monitoring of central nervous system function. In particular, it addresses patients undergoing neurosurgical operations, such as posterior fossa surgery, operative treatment of intracranial aneurysms, spinal cord surgery, cerebrovascular surgery, and operations on the descending aorta. Evoked potentials have been widely employed in neurology since the computer-assisted averaging technique became readily accessible to neurologists. More recent applications are discussed in this book. These require a different approach for monitoring the unconscious patient, often in a rapidly changing clinical situation. Applications of the different stimulus modalities are discussed in relation to the clinical situation of individual patients. SEPs and BAEPs find the widest application in the operating theatre and in evaluating comatose patients.

This book follows the concept of perceiving the entire aorta as one functional organ assuming that all individual pathologies and local interventional procedures affect the up- and downstream segments with consequences for complications and disease progression. Thus any preventive or surgical strategy must recognize the aortic disease in its entirety. The book intends to cover the full spectrum of aortic pathologies, mechanisms and functional interplay. The latest available diagnostic tools and options for surgical treatment are presented by the foremost experts in their field in state-of-the-art reviews. The reader is provided with the most current and comprehensive insight into all fundamental and clinical aspects of aortic disease. All chapters are carefully complemented with figures and illustrations.

This book is a fully updated and revised second edition of a highly successful text in which a new concept of knowledge mining, based on explication and transfer of interventional knowledge of experts, has been implemented. The dedicated training program that is set out will serve the needs of all interventional operators, whether cardiologists, vascular surgeons, vascular specialists, or radiologists, enabling them to achieve a consistent expert level across the entire broad spectrum of catheter-based interventions. Operator skills – and in particular decision-making and strategic skills – are the most critical factors for the outcome of catheter-based cardiovascular interventions. Currently, such skills are commonly developed by the empirical trial and error method only. The explicit teaching, training, and learning approach adopted in this book permits the rapid transfer of interventional knowledge and enables individual operators to negotiate steep learning curves and acquire complex skills in a highly efficient manner. It will thereby offer invaluable assistance in meeting successfully the challenges of modern cardiovascular care.

This extensively updated edition provides a comprehensive review of hypertrophic cardiomyopathy, the most common genetic disorder of the heart characterized by dysfunctional contractility at the sarcomere level. The disease produces abnormal and oftentimes focal hypertrophy on a macroscopic level that further impairs cardiac performance and may lead to life-threatening arrhythmias. This edition provides a practical approach, establishing evidence-based best practice for all scenarios.Hypertrophic Cardiomyopathy provides readers with key points and critical clinical pearls to assist them in managing patients. New chapters have been included on managing hypertension, sleep apnea, coronary artery disease, structural and congenital disease, nutrition and pharmacotherapies. All aspects of treatment are covered – medications, pacemakers and defibrillators, and invasive septal reduction therapy (both surgical myectomy and alcohol septal ablation) – in addition to genetics, family screening, lifestyle concerns, and athletic screening. The practical approach has been reinforced with an expanded emphasis on creating a Center of Excellence, how to facilitate the multi-disciplinary approach, and on case-based reviews and discussions, with each chapter ending with a post-test.This book is an essential text for cardiology professionals from trainee to board-certified physician, and includes important information for interventional cardiologists, cardiac surgeons, cardiac imagers, critical care physicians, sports medicine physicians, genetic counsellors, and electrophysiologists.

This book is a detailed practical guide to the use of ventricular assist devices and total artificial hearts to provide mechanical circulatory support (MCS) in patients with end-stage heart failure. It explains why MCS may be indicated, which patients require MCS, when and how to implant ventricular assist devices or a total artificial heart, and how to avoid potential complications of MCS. Management throughout the period of care is described, from preimplantation to follow-up, and both typical and atypical cases are discussed. The text features numerous helpful tips and tricks relating to surgical and nonsurgical management and is supported by a wealth of high-quality illustrations that document the preoperative evaluation and implantation techniques. Heart transplantation remains the gold standard for the treatment of patients suffering from end-stage heart failure, but the shortage of donors has led to an increase in the use of MCS. This book will assist all physicians, and especially cardiologists and anesthesiologists, who are involved in the care of these patients.

This book covers the fundamentals of tissue engineering for the heart, starting with the basics of organ generation, sensors in tissue and organ fabrication, and the current state-of-the-art in stem cell engineering for the heart. With this foundation in place, the remaining chapters focus on specific aspects of the cardiovascular system, starting with heart muscle, then biological pumps, followed by bioartificial ventricles, and finally, bioartificial hearts. Throughout the course of this book, twenty-two in-depth case studies are presented. Each case study has been selected to illustrate specific design schemes for tissue and organ fabrication. This is an ideal book for upper-level undergraduate and graduate students studying tissue engineering and organ regeneration, especially those focused on cardiac regeneration. This book also: Includes twenty-two case studies that illustrate specific design schemes for engineering the heart Provides open-ended discussion questions at the end of each chapter as well as a detailed reference list to encourage further research and reading Covers the basics of organ fabrication as well as sensor technology and genetic engineering as they relate to tissue and organ fabrication

This book presents and describes a series of informative clinical cases with the aim of providing the reader with a clear understanding of the most frequent and challenging scenarios that a cardiologist may face during daily clinical practice. All major topics in modern clinical cardiology are addressed, including acute ischemic heart disease, conditions that mimic ischemic heart disease, heart failure and resynchronization therapy, cardiomyopathy, valvular heart disease, arrhythmias and channelopathies. Guidance is provided on imaging techniques and their interpretation, patient management taking into account potential comorbidities and follow-up appropriate to the clinical circumstances. The paradigmatic clinical cases in this book will serve as a sound basis for learning for medical students, residents and others wishing to meet successfully the challenges posed by cardiac disease. In addition, the book will be a very useful reference for the more experienced cardiologist.

De zorg voor vaatpatiënten is in twintig jaar aanzienlijk veranderd. Fascinerende technische ontwikkelingen hebben grote invloed gehad op zowel de diagnostiek als de behandeling van patiënten met vaatziekten. Daarnaast worden vaatpatiënten meer en meer behandeld door multidisciplinaire teams bestaande uit medische specialisten van verschillende disciplines en beroepsbeoefenaars met een verpleegkundige achtergrond. Voor gespecialiseerde verpleegkundigen ontstaan dan ook nieuwe rollen. Taken van artsen worden overgenomen door nieuwe categorieën beroepsbeoefenaars, zoals'nurse practitioners'en'physician assistants'.Deze ontwikkelingen vinden nu hun weerslag in dit eerste Nederlandstalig handboek over vasculaire geneeskunde. Klinische zorg rondom de vaatpatiënt belicht de zorg voor patiënten met arteriële en veneuze vaatziekten zowel vanuit medisch als verpleegkundig oogpunt. Elk hoofdstuk begint met een casusbeschrijving en alle secties over specifieke vaatziekten worden afgeslotenmet een samenvatting van verpleegkundige aspecten.

Diagnostik und Therapie der Gefäßkrankheiten wurden in den letzten Jahren revolutioniert. Dieses Werk trägt dieser Entwicklung Rechnung, indem es auch diese neuen Möglichkeiten wie interventionelle Verfahren ausführlich berücksichtigt. Für den zukünftigen Angiologen enthält dieses Buch alle Informationen, die er für seine Facharztausbildung benötigt.

The primary aim in the surgical management of heart disease is an accurate diagnosis. This is achieved by a thorough clinical examination combined with the appropriate special investigations. For convenience, we think in terms of congenital and acquired conditions although the distinction is not always clear. Congenital lesions can usually be subdivided according to the presence or absence of cyanosis. There is also an important intermediate group of conditions which may develop cyanosis on exer­ tion or exercise. In the group of acyanotic lesions it is convenient to divide cases into those with and without a left-to-right shunt. This subdivision is made mainly on the radio­ graphic appearances of the lung fields. The following simple classification will be found helpful in narrowing the diagnostic possibilities in an individual case - Surgical Classification of Heart Disease Cyanotic Congenital Intermittent Heart Disease Cyanosis { Obstructive Lesions Acyanotic { L-R Shunts (lung fields) Endocardium (valves) Myocardium Pericardium Major blood vessels Such a classification cannot hope to be comprehensive but the main groups are covered including the majority of surgically treatable conditions. The major vessels leaving and entering the heart can conveniently be considered in relation to heart disease since coarctation and ductus arteriosus have long since been re­ garded as congenital cardiac surgical problems.

Das seit dem Erscheinen der 1. Auflage im Jahre 1986 sehr erfolgreiche Buch vermittelt, auf praktische Bedürfnisse ausgerichtet, in übersichtlicher Form die Grundlagen der Anästhesie für Herz-+, Thorax- und Gefäßchirurgie. Die vorliegende 5. Auflage wurde umfassend bearbeitet, aktualisiert und erweitert. Abschnitte über die Anästhesie bei Lungentransplantation und alle neuen Anästhesiesubstanzen - um nur einige zu nennen - kommen neu hinzu. Im Kapitel Anästhesie bei Karotisstenoseoperationen werden die Narkose mit Remifentanil und neue intraoperative Überwachungsverfahren ausführlich dargelegt. Das neue Layout und größere Format machen das Buch noch anschaulicher. Es ist und bleibt der unentbehrliche Ratgeber für Anästhesisten, Anästhesieschwestern- und Pfleger und ist zugleich wichtige Informationsquelle Herz-, Thorax- und Gefäßchirurgen, Kardiologen und alle Ärzte, die Patienten mit Herz-Kreislauferkrankungen betreuen.

Zeitgemäßes Krankenhaus-Management unter den neuen Entgeltformen. An dieser aktuellen Aufgabenstellung orientierte sich der III. Workshop'Dokumentationsverfahren in der Herzchirurgie 1997'. Der vorliegende Band faßt unter den Schwerpunkten: - Kostendeckungsprinzip und leistungsorientierte Entgeltformen - Evolution der Informationssysteme sowie deren Ausbreitung in den medizinischen Bereich - Managementinformationen für die Verantwortlichen -'medical controlling'die wesentlichen Aspekte der Tagung zusammen. Traditionell wichtiger Teil ist wiederum der Bericht über die Weiterentwicklung der Qualitätssicherung in der Herzchirurgie.

Die kardiovaskuläre Mortalität in der alten Bundesrepublik zeigte während des letzten Jahrzehnts für die Männer eine geringgradige Abnahme, für die Frauen jedoch eine Zunahme. Vordergründig könnte man meinen, daß somit der Gipfelpunkt kardiovas­ kulärer Erkrankungen erreicht sei. Diese Erkrankungen stellen nach wie vor 50% aller Todesfälle in der Bundesrepublik dar. Aus der jüngsten Erhebung des Augsburger Infarktregisters wissen wir, daß diese Abnahme nicht einhergeht mit einer Optimierung kardiovaskulärer Risikofaktoren. Dies steht in Übereinstimmung mit den Erhebungen im Rahmen des sog. nationalen Untersuchungssurveys der Deutschen Herz-Kreislauf­ Präventionsstudie (DHP), welche an 200 Erhebungspunkten in der alten Bundesrepu­ blik im Abstand von 3 Jahren erhoben wurden, um einen möglichen säkularen Trend zu erfassen. Trotz der Intensivierung von präventiven Maßnahmen ist es in Überein­ stimmung mit den Daten aus dem Augsburger Infarktregister zu einer Zunahme der Häufigkeit der Risikofaktoren gekommen, insbesondere zu einem Anstieg des Serum­ cholesterins und des Körpergewichts, zu praktisch keiner Veränderung beim Rauchver­ halten und nicht zu einer Abnahme der Hypertonie, sondern lediglich zu einer verbes­ serten Therapie der Hypertonie. Auf der anderen Seite ist ein starker Anstieg der speziellen therapeutischen Maßnahmen wie Bypassoperation, Ballondilatation und Herztransplantation in der Bundesrepublik festzustellen. 1990 hatte die Zahl der Dila­ tationen, wie schon 1989, mit 32. 459 wiederum die Zahl der Bypassoperationen (1990: 26. 159) in der Bundesrepublik übertroffen. Man muß somit davon ausgehen, daß die geringfügige Abnahme der Mortalität und der Morbidität, wie sie im Augsburger Infarktregister festgestellt wurde,Folge einer Ver­ besserung des kurativen Systems ist.

Dieser Band behandelt schwerpunktmäßig den Stellenwert neuer diagnostischer Methoden und Therapiestrategien in Kardiologie und Kardiochirurgie. Die einzelnen Beiträge unterziehen sowohl Neuentwicklungen als auch Etabliertes auf dem Sektor Diagnostik und Therapie in beiden Disziplinen einer kritischen Würdigung hinsichtlich ihres Nutzens und Fortschrittes für die Lebensqualität und Prognose der Patienten. Es wird ersichtlich, wie wichtig eine enge Kooperation zwischen Kardiologen und Herzchirurgen ist, um die durch den Fortschritt neu definierten Zielsetzungen verwirklichen zu können. Angesichts der Kostensteigerungen im Gesundheitssystem und andererseits knapper werdender finanzieller Resourcen, ist ein weiterer Schwerpunkt auch den sozioökonomischen Bedingungen der universitären High-Tech-Medizin gewidmet. So wird in den Beiträgen das derzeit medizinisch Machbare auch immer einer Kosten-Nutzen-+Analyse unterzogen.

Diese 2., völlig neu bearbeitete und erweiterte Auflage des Herzbandes der Kirschnerschen Operationslehre verdeutlicht den rasanten Fortschritt der kardiovaskulären Chirurgie. Die heute in großem Umfang ausgeübten traditionellen Verfahren wurden auf den neuesten Stand der Erkenntnis gebracht. Zahlreiche zusätzliche Kapitel schildern Operationsverfahren, die bei der 1. Auflage noch im Entwicklungsstadium standen oder damals noch gar nicht bekannt waren, wie z.B.: korrigierende Operationen bei Herzfehlern im Neugeborenenalter, die arterielle'Switch'-Operation bei Transposition der großen Arterien, die Herz-, Herz-Lungen- und Lungen-Transplantation oder die elektrophysiologisch geleitete antiarrhythmische Chirurgie. Für alle Kapitel konnten Autoren mit großer Erfahrung bei der operativen Behandlung der von ihnen beschriebenen Krankheitsbilder gewonnen werden. Die Ausstattung ist vorbildlich; das reichlich verwendete Bildmaterial und die schematischen Zeichnungen sind instruktiv und ergänzen den Text hervorragend. Das Werk spiegelt den neuesten Stand der kardiovaskulären Chirurgie wider.

Mit diesem Buch wird erstmals ein klinisch orientiertes Werk zum Thema SPECT des Herzens vorgestellt. Es werden Grundlagen, Qualitätskontrolle, Radiopharmaka und alle klinischen Anwendungen dargestellt, die derzeit eine sichere Diagnose von Herzkrankheiten ermöglichen. Nicht nur die Sichtweisen des Nuklearmediziners sondern auch die Erwartungen der Kardiologen und Kardiochirurgen werden berücksichtigt.

Ein praktischer Leitfaden, wenn Sie mit Gefäßintervention beginnen oder sich in den modernen Techniken und Materialien fortbilden möchten. Die Autoren vermitteln das Wissen für die Praxis umfassend, aber präzise, klar in Text und Didaktik, anschaulich durch zahlreiche Abbildungen und Tabellen.'Eine fesselnde Lektüre... Wer interventionell nicht tätig ist, wird animiert, wer interventionell arbeitet, wird inspiriert...'(Der Radiologe)

Posttraumatic stump formation and replantation of the severed limb are both reconstructive plastic operations which may lead to the improvement or destruction of a patient's lifestyle. For the primary attending surgeon, the decision whether to undertake such an operation depends on the patient's clinical condition, the operational circumstances, the psychological and social aspects and, last but not least, on the surgeon's own abilities. This monograph is designed as a synopsis of the great number of patho-physiological parameters and surgical and rehabilitational aspects which must be considered in the analysis of complications in major limb replantation. In addition, basic information about the key role of ischemic myopathy and microangiopathy is supplied to encourage further experimental investigations.

The management of diseases of the venous system has evolved rapidly over the last forty years. Much of this development occured since the creation of the Union Internationale de Phlebologie (UIP) in 1959 which has helped to bring together those involved in the management of venous diseases. The Proceedings of the XII World Congress of the UIP will reflect the diversity of disciplines involved (such as phlebologists, dermatologists, surgeons, physiologists and radiologists) as well as new methods of investigation, prevention and the latest research on the topic.

In this book, the latest results in coronary artery surgery are discussed and the factors decisive for long-term prognosis are elucidated. The indications for re-operation are considered and redefined, and the surgical technique with regard to multiple bypass is described. The aim of the book is to depict clearly long-term prognoses and to determinate the future needs of coronary artery surgery in the next decade. This far-sighted approach also makes the book a valuable reference for the planning and extension of cardiology centers in Europe. 1