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Introduction: Dandelion (Taraxacum officinale) is an edible and medicinal plant. We use the leaves, flowers and roots. The objective of this study is to show interest in the use of dandelion as a natural remedy in the primary treatment of serval pathologies. Methods : An ethnobotanical survey of 1000 people in the western region of Algeria was conducted using a questionnaire. Results: the obtained results from this study show that 60% of the population questioned prefer traditional medicine the majority of them use the plant in the medical field whose leaves and roots are most used. Infusion and maceration are the most usable methods for the preparation of the plant and administration is exclusively oral. Most users testify that the plant has significant efficacy with a percentage of 61%. Conclusion :All this information constitutes a database to perform other research in vivo or in vitro to value this planton the therapeutic level. Keywords : Taraxacum Officinale, traditional medicine, leaves, ethnobotanical study.

Introduction Autism is a neurodevelopmental disorder that manifests before 3 years old and affects many areas, communication, social interactions and behaviors. In Algeria, there has not yet been a regional or national epidemiological investigation concerning autism spectrum disorders. Materials and methods: Our study was carried about 100 patients ( autistic children) in the western region of Algeria, in order to determine the differents risk factors involved in the onset of autism syndrome. Results and discussion: The obtained results indicate a male predominance with a sex ratio of 4: 1 and the degree of reached is average in 44% of patients. 42% of the patients are youngsters. Parents' worry about their children begins between 24 and 36 months. The parents' advanced age at conception, stress, presence of certain pathologies and drug intake by mothers, as well as fetal distress at birth and children's exposure to screens were the main risk factors. Repetitive movements, lack of social communication, language delay, and lack of visual fixation were the main clinical symptomatology. Conclusion: This study allowed us to detect the main factors associated with the onset of autism. However, the results obtained cannot be generalized to the entire population. Keywords: Autism, autism spectrum disorder, risk factors, clinical symptoms, western region of Algeria.

Objectives: To determine the epidemiological, clinical, histological, serological and therapeutic profile of celiac disease in children in Western Algeria region.Methods: 250 patients over a period of three years (2016 - 2019) from the pediatric department of the University Hospital of Oran (West Algeria) were included in our retrospective study.Results: We noticed a female predominance with a sex ratio F/M = 1.57. Symptoms were defined by typical (73.2%) and atypical (26.8%) forms, digestive disorders (47.2%), extra digestive disorders (14.4%). Anemia was noted at 73.6%, and the association with autoimmune diseases at 14.8%. Seropositivity was present in 77.6% of cases and histology revealed partial grade villous atrophy at 54%. We noticed a significant link between the histological grade and the serology (p = 0.001), between age and histological grade (p

Introduction: Dandelion (Taraxacum officinale) is a medicinal plant used in alternative medicine for its multiple therapeutic and preventive properties. However, insufficient data are available about its toxicity. Materials and methods: dandelion roots total extract vas prepared by maceration for 24 hours and its toxicity was then assessed on 30 WISTAR male rats divided into four experimental groups receiving the extract at different rates, and one control group treated with the vehicle. Changes in renal, hepatic, lipid, and hematological parameters as well as signs of acute toxicity were noted during 15 days after the one dose extract administration. Results and discussion: The obtained results reveal a very significant (p

Object: Cervical cancer of the uterine (CCU) is the first cancer of the genital tract. In Algeria, this cancer remains a real public health problem. The diagnosis is still done often with advanced stages which makes the therapeutic results modest and the cost of the high care. Methodology: Our study aims to elucidate the reality of this type of pathology in the region of Sidi Bel Abbes, northwestern Algeria. This retrospective and descriptive study was devoted to the epidemiological and clinical analysis of cervical cancer cases over a period of 3 years. Results: This study shows that out of a total of 500 smears recorded between (2014-2016) at the Ana-pathology laboratory level in Sidi Bel Abbes, we found that 230 smears presented precancerous lesions according to a cytological study, atypical squamous cells of undetermined significance (ASC-US: were 18%; low-grade squamous intraepithelial lesions (LSIL) were 20%, while high-grade squamous intraepithelial lesions (HSIL) were 8%. The results obtained according to the distribution of the patients in relation to the various factors: the most affected age group is late 46-55 years with a total of 40%; precocious age of 1st report 18-20 years is (38.2%); gestation 4-5 pregnancies and parities 4-5 children with a rate of (38.70% and 32.6%) respectively ; the hormonal state in genital activity is estimated at 62.2%; patients on oral contraception (OC) have a rate of 48.9%. Finally, more than half of the patients (57.8%), were able to have a biopsy within three to four months of the last smear. In histology, the presence of a HPV (Human Papilloma Virus) low grade lesion does not predict the evolution of this lesion. Conclusion: HPV can be oncogenic or non-oncogenic. it is the oncogenic HPV infection that is the main risk factor for developing a high grade lesion and cervical cancers outside the associated cofactors. Keywords: Pap Smear, Precancerous lesion, Cancer, Cervix, Screening

Bisphenol A (BPA) is an endocrine disruptor chemical widely used in the manufacture of polycarbonate plastics and epoxy resins found in everyday consumer products including food and beverage containers. This molecule was recently incriminated as a potential initiator for a number of diseases such as uterine fibromas, a frequent gynecological benign tumor that affects women’s fertility and life quality. The present study aims to investigate the association between uterine leiomyoma and BPA plasma levels in a population of Algerian women. Eighty plasma samples were collected from women with confirmed uterine fibroids diagnosis (N=40) and healthy volunteers without uterine leiomyomas (N=40) recruited at the specialized Hospital of Gynecology and Obstetrics of Sidi Bel Abbes in the western region of Algeria. Uterine leiomyoma subjects were then divided into three groups according to tumor growth and severity. BPA plasma levels were detected and measured using an enzyme linked immunosorbent assay (ELISA) technique. Seventy five percent of uterine leiomyoma patients were exposed to BPA and were principally young nulliparous women aged from 31 to 40 years expressing significantly higher plasma BPA levels than controls (0.89 ± 1.65 vs 0.05 ± 0.12 ng/mL; P=0.0001). Concerning the relationship between tumor growth and BPA levels, even though mean concentration was slightly higher in the severe group than the moderate group, the difference was statistically insignificant (P=0.97). These preliminary results suggest an association between environmental exposure to BPA and the occurrence of uterine fibroids among an Algerian female population of child-bearing age. Nevertheless, further studies on larger populations are required to confirm these findings.