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There is a tremendous amount of interest in AI/ML technologies due to the proliferation of generative AI applications such as ChatGPT. This trend has significantly increased demand on GPUs, which are the workhorses for training AI models. Due to the high costs of GPUs and lacking supply, it has become of interest to optimize GPU usage in HPC centers. MIT Lincoln Laboratory Supercomputing Center (LLSC) has developed an easy-to-use GPU sharing feature supported by LLSC-developed tools including LLsub and LLMapReduce. This approach overcomes some of the limitations with the existing methods for GPU sharing. This allows users to apply GPU sharing whenever possible while they are developing their AI/ML models and/or doing parametric study on their AI models or executing other GPU applications. Based on our initial experimental results with GPU sharing, GPU sharing with triples mode is easy to use and achieved significant improvement in GPU usage and throughput performance for certain types of AI applications.

The increasing use and cost of high performance computing (HPC) requires new easy-to-use tools to enable HPC users and HPC systems engineers to transparently understand the utilization of resources. The MIT Lincoln Laboratory Supercomputing Center (LLSC) has developed a simple command, LLload, to monitor and characterize HPC workloads. LLload plays an important role in identifying opportunities for better utilization of compute resources. LLload can be used to monitor jobs both programmatically and interactively. LLload can characterize users' jobs using various LLload options to achieve better efficiency. This information can be used to inform the user to optimize HPC workloads and improve both CPU and GPU utilization. This includes improvements using judicious oversubscription of the computing resources. Preliminary results suggest significant improvement in GPU utilization and overall throughput performance with GPU overloading in some cases. By enabling users to observe and fix incorrect job submission and/or inappropriate execution setups, LLload can increase the resource usage and improve the overall throughput performance. LLload is a light-weight, easy-to-use tool for both HPC users and HPC systems engineers to monitor HPC workloads to improve system utilization and efficiency.

Recently, an interesting pattern was found in the differential equations satisfied by the Feynman integrals describing tree-level correlators of conformally coupled scalars in a power-law FRW cosmology [1,2]. It was proven that simple and universal graphical rules predict the equations for arbitrary graphs as a flow in kinematic space. In this note, we show that the same rules$\unicode{x2013}$with one small addition$\unicode{x2013}$also determine the differential equations for loop integrands. We explain that both the basis of master integrals and the singularities of the differential equations can be represented by tubings of marked graphs. An important novelty in the case of loops is that some basis functions can vanish, and we present a graphical rule to identify these vanishing functions. Taking this into account, we then demonstrate that the kinematic flow correctly predicts the differential equations for all loop integrands., Comment: 32 pages

We examine the speed of different boarding methods in a proposed Flying Wing aircraft design with four aisles using an agent-based model. We study the effect of various passenger movement variables on the boarding process. We evaluate the impact of these factors on the boarding time when the boarding process runs sequentially and in parallel with the aisles of the Flying Wing layout. Then, we analyze the impact of an increase in the number of aisles on the relative speed of all boarding methods and conclude that methods utilizing boarding of the separate aisles simultaneously (parallel boarding) converge to the fastest boarding time given by the Steffen method. With parallel boarding of the aisles the relative advantage of the Steffen method compared to Windows-Middle-Aisle (WMA) or Back-to-front boarding decreases, from being 1.6-2.1 times as fast to being approximately equal for our fiducial Flying Wing seating arrangement. Standard methods such as Back-to-front or WMA are about twice as fast to board a four-aisle Flying Wing plane, compared to a single-aisle aircraft with the same number of passengers. We also investigate the difference between the optimal approach to parallel boarding, where consecutive passengers always enter separate aisles, and a less optimal but more practical approach. The practical approach is only up to 1.06 times slower than the optimal, meaning that the advantages of parallel boarding can be utilized without resorting to impractical boarding methods. Hence, the introduction of multiple aisles into aircraft seating design offers the prospect of significantly decreasing the boarding time for passengers, without the introduction of inconvenient boarding methods., Comment: 25 pages, 9 figures

We present a new method for evaluating tensor integrals in the large-scale structure. Decomposing a $\Lambda$CDM-like universe into a finite sum of scaling universes using the FFTLog, we can recast loop integrals for biased tracers in the large-scale structure as certain tensor integrals in quantum field theory. While rotational symmetry is spontaneously broken by the fixed reference frame in which biased tracers are observed, the tensor structures can still be organized to respect the underlying symmetry. Projecting the loop integrands for scaling universes onto spherical harmonics, the problem effectively reduces to the evaluation of one-dimensional radial integrals, which can be solved analytically. Using this method, we derive analytic expressions for the one-loop power spectrum, bispectrum, and trispectrum for arbitrary multipole moments in the basis of scaling universes., Comment: 5+7 pages

Off-axis digital holographic microscopy is a high-throughput, label-free imaging technology that provides three-dimensional, high-resolution information about samples, particularly useful in large-scale cellular imaging. However, the hologram reconstruction process poses a significant bottleneck for timely data analysis. To address this challenge, we propose a novel reconstruction approach that integrates deep learning with the physical principles of off-axis holography. We initialized part of the network weights based on the physical principle and then fine-tuned them via weakly supersized learning. Our off-axis hologram network (OAH-Net) retrieves phase and amplitude images with errors that fall within the measurement error range attributable to hardware, and its reconstruction speed significantly surpasses the microscope's acquisition rate. Crucially, OAH-Net demonstrates remarkable external generalization capabilities on unseen samples with distinct patterns and can be seamlessly integrated with other models for downstream tasks to achieve end-to-end real-time hologram analysis. This capability further expands off-axis holography's applications in both biological and medical studies., Comment: 11 pages, 4 figures

Attention is the cornerstone of modern Large Language Models (LLMs). Yet its quadratic complexity limits the efficiency and scalability of LLMs, especially for those with a long-context window. A promising approach addressing this limitation is to leverage the sparsity in attention. However, existing sparsity-based solutions predominantly rely on predefined patterns or heuristics to approximate sparsity. This practice falls short to fully capture the dynamic nature of attention sparsity in language-based tasks. This paper argues that attention sparsity should be learned rather than predefined. To this end, we design SeerAttention, a new Attention mechanism that augments the conventional attention with a learnable gate that adaptively selects significant blocks in an attention map and deems the rest blocks sparse. Such block-level sparsity effectively balances accuracy and speedup. To enable efficient learning of the gating network, we develop a customized FlashAttention implementation that extracts the block-level ground truth of attention map with minimum overhead. SeerAttention not only applies to post-training, but also excels in long-context fine-tuning. Our results show that at post-training stages, SeerAttention significantly outperforms state-of-the-art static or heuristic-based sparse attention methods, while also being more versatile and flexible to adapt to varying context lengths and sparsity ratios. When applied to long-context fine-tuning with YaRN, SeerAttention can achieve a remarkable 90% sparsity ratio at a 32k context length with minimal perplexity loss, offering a 5.67x speedup over FlashAttention-2.

Analysing stellar parameters and abundances from nearly one million Gaia DR3 Radial Velocity Spectrometer (RVS) spectra poses challenges due to the limited spectral coverage (restricted to the infrared Ca II triplet) and variable signal-to-noise ratios of the data. To address this, we use The Cannon, a data-driven method, to transfer stellar parameters and abundances from the GALAH Data Release 4 (DR4; R ~ 28,000) catalogue to the lower resolution Gaia DR3 RVS spectra (R ~ 11,500). Our model, trained on 14,484 common targets, predicts parameters such as Teff, log g, and [Fe/H], along with several other elements across approximately 800,000 Gaia RVS spectra. We utilise stars from open and globular clusters present in the Gaia RVS catalogue to validate our predicted mean [Fe/H] with high precision (~0.02-0.10 dex). Additionally, we recover the bimodal distribution of [Ti/Fe] versus [Fe/H], reflecting the high and low alpha-components of Milky Way disk stars, demonstrating The Cannon's capability for accurate stellar abundance determination from medium-resolution Gaia RVS spectra. The methodologies and resultant catalogue presented in this work highlight the remarkable potential of the RVS dataset, which by the end of the Gaia mission will comprise spectra of over 200 million stars., Comment: Submitted to MNRAS, 16 pages, 15 figures

Function-as-a-Service (FaaS) is a growing cloud computing paradigm that is expected to reduce the user cost of service over traditional serverful approaches. However, the environmental impact of FaaS has not received much attention. We investigate FaaS scheduling and scaling from a sustainability perspective in this work. We find that the service-level objectives (SLOs) of FaaS and carbon emissions conflict with each other. We also find that SLO-focused FaaS scheduling can exacerbate water use in a datacenter. We propose a novel sustainability-focused FaaS scheduling and scaling framework to co-optimize SLO performance, carbon emissions, and wastewater generation.

Real-time supercomputing performance analysis is a critical aspect of evaluating and optimizing computational systems in a dynamic user environment. The operation of supercomputers produce vast quantities of analytic data from multiple sources and of varying types so compiling this data in an efficient matter is critical to the process. MIT Lincoln Laboratory Supercomputing Center has been utilizing the Unity 3D game engine to create a Digital Twin of our supercomputing systems for several years to perform system monitoring. Unity offers robust visualization capabilities making it ideal for creating a sophisticated representation of the computational processes. As we scale the systems to include a diversity of resources such as accelerators and the addition of more users, we need to implement new analysis tools for the monitoring system. The workloads in research continuously change, as does the capability of Unity, and this allows us to adapt our monitoring tools to scale and incorporate features enabling efficient replay of system wide events, user isolation, and machine level granularity. Our system fully takes advantage of the modern capabilities of the Unity Engine in a way that intuitively represents the real time workload performed on a supercomputer. It allows HPC system engineers to quickly diagnose usage related errors with its responsive user interface which scales efficiently with large data sets.

Superfast rotators (SFRs) are small solar system objects that rotate faster than generally possible for a cohesionless rubble pile. Their rotational characteristics allow us to make inferences about their interior structure and composition. Here, we present the methods and results from a preliminary search for SFRs in the DECam Ecliptic Exploration Project (DEEP) data set. We find three SFRs from a sample of 686 main-belt asteroids, implying an occurrence rate of 0.4 -0.3/+0.1 percent - a higher incidence rate than has been measured by previous studies. We suggest that this high occurrence rate is due to the small sub-kilometer size regime to which DEEP has access: the objects searched here were as small as 500 m. We compute the minimum required cohesive strength for each of these SFRs and discuss the implications of these strengths in the context of likely evolution mechanisms. We find that all three of these SFRs require strengths that are more than that of weak regolith but consistent with many cohesive asteroid strengths reported in the literature. Across the full DEEP data set, we have identified ~70,000 Main-Belt Asteroids and expect ~300 SFRs - a result that will be assessed in a future paper.

The recent cohort of publicly available generative models can produce human expert level content across a variety of topics and domains. Given a model in this cohort as a base model, methods such as parameter efficient fine-tuning, in-context learning, and constrained decoding have further increased generative capabilities and improved both computational and data efficiency. Entire collections of derivative models have emerged as a byproduct of these methods and each of these models has a set of associated covariates such as a score on a benchmark, an indicator for if the model has (or had) access to sensitive information, etc. that may or may not be available to the user. For some model-level covariates, it is possible to use "similar" models to predict an unknown covariate. In this paper we extend recent results related to embedding-based representations of generative models -- the data kernel perspective space -- to classical statistical inference settings. We demonstrate that using the perspective space as the basis of a notion of "similar" is effective for multiple model-level inference tasks.

Neural scaling laws play a pivotal role in the performance of deep neural networks and have been observed in a wide range of tasks. However, a complete theoretical framework for understanding these scaling laws remains underdeveloped. In this paper, we explore the neural scaling laws for deep operator networks, which involve learning mappings between function spaces, with a focus on the Chen and Chen style architecture. These approaches, which include the popular Deep Operator Network (DeepONet), approximate the output functions using a linear combination of learnable basis functions and coefficients that depend on the input functions. We establish a theoretical framework to quantify the neural scaling laws by analyzing its approximation and generalization errors. We articulate the relationship between the approximation and generalization errors of deep operator networks and key factors such as network model size and training data size. Moreover, we address cases where input functions exhibit low-dimensional structures, allowing us to derive tighter error bounds. These results also hold for deep ReLU networks and other similar structures. Our results offer a partial explanation of the neural scaling laws in operator learning and provide a theoretical foundation for their applications.

The stars of the Milky Way carry the chemical history of our Galaxy in their atmospheres as they journey through its vast expanse. Like barcodes, we can extract the chemical fingerprints of stars from high-resolution spectroscopy. The fourth data release (DR4) of the Galactic Archaeology with HERMES (GALAH) Survey, based on a decade of observations, provides the chemical abundances of up to 32 elements for 917 588 stars that also have exquisite astrometric data from the $Gaia$ satellite. For the first time, these elements include life-essential nitrogen to complement carbon, and oxygen as well as more measurements of rare-earth elements critical to modern-life electronics, offering unparalleled insights into the chemical composition of the Milky Way. For this release, we use neural networks to simultaneously fit stellar parameters and abundances across the full spectrum, leveraging synthetic grids computed with Spectroscopy Made Easy. These grids account for atomic line formation in non-local thermodynamic equilibrium for 14 elements. In a two-iteration process, we first fit stellar labels for all 1 085 520 spectra, then co-add repeated observations and refine these labels using astrometric data from $Gaia$ and 2MASS photometry, improving the accuracy and precision of stellar parameters and abundances. Our validation thoroughly assesses the reliability of spectroscopic measurements and highlights key caveats for catalogue users. GALAH DR4 represents yet another milestone in Galactic archaeology, combining detailed chemical compositions from multiple nucleosynthetic channels with kinematic information and age estimates. The resulting dataset, covering nearly a million stars, opens new avenues for understanding not only the chemical and dynamical history of the Milky Way, but also the broader questions of the origin of elements and the evolution of planets, stars, and galaxies., Comment: 43 pages, 38 figures to be submitted to PASA. Accompanying the GALAH Data Release 4, see https://www.galah-survey.org and https://cloud.datacentral.org.au/teamdata/GALAH/public/GALAH_DR4/. All code available on http://github.com/svenbuder/GALAH_DR4/ and https://github.com/svenbuder/galah_dr4_paper. Comments welcome

Generative models, such as large language models and text-to-image diffusion models, produce relevant information when presented a query. Different models may produce different information when presented the same query. As the landscape of generative models evolves, it is important to develop techniques to study and analyze differences in model behaviour. In this paper we present novel theoretical results for embedding-based representations of generative models in the context of a set of queries. We establish sufficient conditions for the consistent estimation of the model embeddings in situations where the query set and the number of models grow.

Sequential learning involves learning tasks in a sequence, and proves challenging for most neural networks. Biological neural networks regularly conquer the sequential learning challenge and are even capable of transferring knowledge both forward and backwards between tasks. Artificial neural networks often totally fail to transfer performance between tasks, and regularly suffer from degraded performance or catastrophic forgetting on previous tasks. Models of associative memory have been used to investigate the discrepancy between biological and artificial neural networks due to their biological ties and inspirations, of which the Hopfield network is perhaps the most studied model. The Dense Associative Memory, or modern Hopfield network, generalizes the Hopfield network, allowing for greater capacities and prototype learning behaviors, while still retaining the associative memory structure. We investigate the performance of the Dense Associative Memory in sequential learning problems, and benchmark various sequential learning techniques in the network. We give a substantial review of the sequential learning space with particular respect to the Hopfield network and associative memories, as well as describe the techniques we implement in detail. We also draw parallels between the classical and Dense Associative Memory in the context of sequential learning, and discuss the departures from biological inspiration that may influence the utility of the Dense Associative Memory as a tool for studying biological neural networks. We present our findings, and show that existing sequential learning methods can be applied to the Dense Associative Memory to improve sequential learning performance.

Hypersparse traffic matrices constructed from network packet source and destination addresses is a powerful tool for gaining insights into network traffic. SuiteSparse: GraphBLAS, an open source package or building, manipulating, and analyzing large hypersparse matrices, is one approach to constructing these traffic matrices. Suricata is a widely used open source network intrusion detection software package. This work demonstrates how Suricata network flow records can be used to efficiently construct hypersparse matrices using GraphBLAS.

Symbolic encoding has been used in multi-operator learning as a way to embed additional information for distinct time-series data. For spatiotemporal systems described by time-dependent partial differential equations, the equation itself provides an additional modality to identify the system. The utilization of symbolic expressions along side time-series samples allows for the development of multimodal predictive neural networks. A key challenge with current approaches is that the symbolic information, i.e. the equations, must be manually preprocessed (simplified, rearranged, etc.) to match and relate to the existing token library, which increases costs and reduces flexibility, especially when dealing with new differential equations. We propose a new token library based on SymPy to encode differential equations as an additional modality for time-series models. The proposed approach incurs minimal cost, is automated, and maintains high prediction accuracy for forecasting tasks. Additionally, we include a Bayesian filtering module that connects the different modalities to refine the learned equation. This improves the accuracy of the learned symbolic representation and the predicted time-series.

HPC systems used for research run a wide variety of software and workflows. This software is often written or modified by users to meet the needs of their research projects, and rarely is built with security in mind. In this paper we explore several of the key techniques that MIT Lincoln Laboratory Supercomputing Center has deployed on its systems to manage the security implications of these workflows by providing enforced separation for processes, filesystem access, network traffic, and accelerators to make every user feel like they are running on a personal HPC.

We propose PROSE-FD, a zero-shot multimodal PDE foundational model for simultaneous prediction of heterogeneous two-dimensional physical systems related to distinct fluid dynamics settings. These systems include shallow water equations and the Navier-Stokes equations with incompressible and compressible flow, regular and complex geometries, and different buoyancy settings. This work presents a new transformer-based multi-operator learning approach that fuses symbolic information to perform operator-based data prediction, i.e. non-autoregressive. By incorporating multiple modalities in the inputs, the PDE foundation model builds in a pathway for including mathematical descriptions of the physical behavior. We pre-train our foundation model on 6 parametric families of equations collected from 13 datasets, including over 60K trajectories. Our model outperforms popular operator learning, computer vision, and multi-physics models, in benchmark forward prediction tasks. We test our architecture choices with ablation studies.

The MIT/IEEE/Amazon GraphChallenge encourages community approaches to developing new solutions for analyzing graphs and sparse data derived from social media, sensor feeds, and scientific data to discover relationships between events as they unfold in the field. The anonymized network sensing Graph Challenge seeks to enable large, open, community-based approaches to protecting networks. Many large-scale networking problems can only be solved with community access to very broad data sets with the highest regard for privacy and strong community buy-in. Such approaches often require community-based data sharing. In the broader networking community (commercial, federal, and academia) anonymized source-to-destination traffic matrices with standard data sharing agreements have emerged as a data product that can meet many of these requirements. This challenge provides an opportunity to highlight novel approaches for optimizing the construction and analysis of anonymized traffic matrices using over 100 billion network packets derived from the largest Internet telescope in the world (CAIDA). This challenge specifies the anonymization, construction, and analysis of these traffic matrices. A GraphBLAS reference implementation is provided, but the use of GraphBLAS is not required in this Graph Challenge. As with prior Graph Challenges the goal is to provide a well-defined context for demonstrating innovation. Graph Challenge participants are free to select (with accompanying explanation) the Graph Challenge elements that are appropriate for highlighting their innovations., Comment: Accepted to IEEE HPEC 2024

As particle accelerators grow in complexity, traditional control methods face increasing challenges in achieving optimal performance. This paper envisions a paradigm shift: a decentralized multi-agent framework for accelerator control, powered by Large Language Models (LLMs) and distributed among autonomous agents. We present a proposition of a self-improving decentralized system where intelligent agents handle high-level tasks and communication and each agent is specialized control individual accelerator components. This approach raises some questions: What are the future applications of AI in particle accelerators? How can we implement an autonomous complex system such as a particle accelerator where agents gradually improve through experience and human feedback? What are the implications of integrating a human-in-the-loop component for labeling operational data and providing expert guidance? We show two examples, where we demonstrate viability of such architecture., Comment: 4 pages, 3 figures, Machine Learning and the Physical Sciences at Workshop at the 38th conference on Neural Information Processing Systems (NeurIPS)

Understanding what is normal is a key aspect of protecting a domain. Other domains invest heavily in observational science to develop models of normal behavior to better detect anomalies. Recent advances in high performance graph libraries, such as the GraphBLAS, coupled with supercomputers enables processing of the trillions of observations required. We leverage this approach to synthesize low-parameter observational models of anonymized Internet traffic with a high regard for privacy., Comment: Accepted to IEEE HPEC, 7 pages, 6 figures, 1 table, 41 references

Single-operator learning involves training a deep neural network to learn a specific operator, whereas recent work in multi-operator learning uses an operator embedding structure to train a single neural network on data from multiple operators. Thus, multi-operator learning is capable of predicting a range of operators within one model. In this work, we propose pretraining and fine-tuning strategies for solving PDEs using multi-operator learning. One key aspect is that by increasing the number of families of operators used in pretraining, a PDE foundation model can be fine-tuned to downstream tasks involving new PDEs with a limited number of samples, thus outperforming single operator neural networks. Specifically, a multi-operator learning model pre-trained with data from diverse PDE families can predict unseen operators after fine-tuning with only a limited number of operators from the new family, enabling them to serve as a data-free PDE solver. We also show that the proposed training and fine-tuning method is able to predict new operators in zero-shot prediction without samples. Additionally, we introduce a PDE-agnostic meta-learning algorithm to improve the adaptability of the model to various PDEs by providing a better parameter initialization process. To address the needs of applications with limited computing resources, we explore low-rank adaptation methods that reduce computational costs while enhancing solver accuracy. Lastly, by examining the scaling law with respect to the number of operator families, we establish and highlight its potential for broad adaptation in PDE-solving tasks.

Stellar streams in the Milky Way are promising detectors of low-mass dark matter (DM) subhalos predicted by $\Lambda$CDM. Passing subhalos induce perturbations in streams that indicate the presence of the subhalos. Understanding how known DM-dominated satellites impact streams is a crucial step towards using stream perturbations to constrain the properties of dark perturbers. Here, we cross-match a $\textit{Gaia}$ EDR3 and SEGUE member catalog of the Cetus-Palca stream (CPS) with H3 for additional radial velocity measurements and fit the orbit of the CPS using this 6-D data. We demonstrate for the first time that the ultra-faint dwarf Segue 2 had a recent (77$\pm$5 Myr ago) close flyby (within the stream's 2$\sigma$ width) with the CPS. This interaction enables constraints on Segue 2's mass and density profile at larger radii ($\mathcal{O}(1)$ kpc) than are probed by its stars ($\mathcal{O}(10)$ pc). While Segue 2 is not expected to strongly affect the portion of the stream covered by our 6-D data, we predict that if Segue 2's mass within $\sim 6$ kpc is $5\times 10^9\,M_\odot$, the CPS's velocity dispersion will be $\sim 40$ km/s larger ahead of the impact site than behind it. If no such heating is detected, Segue 2's mass cannot exceed $10^9\,M_\odot$ within $\sim 6$ kpc. The proper motion distribution of the CPS near the impact site is mildly sensitive to the shape of Segue 2's density profile. This study presents a critical test for frameworks designed to constrain properties of dark subhalos from stream perturbations., Comment: 33 pages, 14 figures, 6 tables. Submitted to ApJ, comments welcome

This project investigates the efficacy of Large Language Models (LLMs) in understanding and extracting scientific knowledge across specific domains and to create a deep learning framework: Knowledge AI. As a part of this framework, we employ pre-trained models and fine-tune them on datasets in the scientific domain. The models are adapted for four key Natural Language Processing (NLP) tasks: summarization, text generation, question answering, and named entity recognition. Our results indicate that domain-specific fine-tuning significantly enhances model performance in each of these tasks, thereby improving their applicability for scientific contexts. This adaptation enables non-experts to efficiently query and extract information within targeted scientific fields, demonstrating the potential of fine-tuned LLMs as a tool for knowledge discovery in the sciences., Comment: 11 pages

Microfluidic technology has emerged as a powerful tool for studying complex biological processes with enhanced precision and control. A microfluidic chip was designed to emulate human-like microvascular networks with precise control over channel geometry and flow conditions. By simulating blood flow dynamics during bleeding events, we successfully observed the real-time interactions of platelets and their aggregation induced by shear rate gradient at the wound site. Platelet dynamics is primarily influenced by physico-mechanical condition of blood vessels with pathophysiological condition of blood at close proximity of vascular injury site. This microfluidic platform facilitated the investigation of platelet adhesion, activation, and clot formation, providing a unique opportunity to study the spatiotemporal dynamics of platelet aggregation and blood clot. Our findings shed light on the intricate mechanisms underlying thrombus formation and platelet-mediated aggregation, offering a more accurate and dynamic representation of human haemostasis compared to traditional animal models. In the conventional approach, the human bleeding model is tried on mouse due to anatomy and pathological similarities between mouse and humans. This study will simplify and standardize the blood and vasculature conditions. The microfluidic-based replication of the bleeding model holds significant promise in advancing our understanding of clotting disorders and wound healing processes. Furthermore, it paves the way for targeted therapeutic interventions in managing bleeding disorders and enhancing clinical strategies for promoting efficient wound closure. Ultimately, this study demonstrates the potential of microfluidics to revolutionize haemostasis research and opens up new avenues for the development of personalized medicine approaches in the field of clotting disorders., Comment: 11 pages, 8 figures

We report the detection of 239 trans-Neptunian Objects discovered through the on-going New Horizons survey for distant minor bodies being performed with the Hyper Suprime-Cam mosaic imager on the Subaru Telescope. These objects were discovered in images acquired with either the r2 or the recently commissioned EB-gri filter using shift and stack routines. Due to the extremely high stellar density of the search region down stream of the spacecraft, new machine learning techniques had to be developed to manage the extremely high false positive rate of bogus candidates produced from the shift and stack routines. We report discoveries as faint as r2$\sim26.5$. We highlight an overabundance of objects found at heliocentric distances $R\gtrsim70$~au compared to expectations from modelling of the known outer Solar System. If confirmed, these objects betray the presence of a heretofore unrecognized abundance of distant objects that can help explain a number of other observations that otherwise remain at odds with the known Kuiper Belt, including detections of serendipitous stellar occultations, and recent results from the Student Dust Counter on-board the New Horizons spacecraft., Comment: Accepted for publication in the Planetary Science Journal, 28 pages, 7 figures, 3 tables

Estimating many-body effects that deviate from an independent particle approach, has long been a key research interest in condensed matter physics. Layered cuprates are prototypical systems, where electron-electron interactions are found to strongly affect the dynamics of single-particle excitations. It is however, still unclear how the electron correlations influence charge excitations, such as plasmons, which have been variously treated with either weak or strong correlation models. In this work, we demonstrate the hybridised nature of collective valence charge fluctuations leading to dispersing acoustic-like plasmons in hole-doped La$_{1.84}$Sr$_{0.16}$CuO$_{4}$ and electron-doped La$_{1.84}$Ce$_{0.16}$CuO$_{4}$ using the two-particle probe, resonant inelastic x-ray scattering. We then describe the plasmon dispersions in both systems, within both the weak mean-field Random Phase Approximation (RPA) and strong coupling $t$-$J$-$V$ models. The $t$-$J$-$V$ model, which includes the correlation effects implicitly, accurately describes the plasmon dispersions as resonant excitations outside the single-particle intra-band continuum. In comparison, a quantitative description of the plasmon dispersion in the RPA approach is obtained only upon explicit consideration of re-normalized electronic band parameters. Our comparative analysis shows that electron correlations significantly impact the low-energy plasmon excitations across the cuprate doping phase diagram, even at long wavelengths. Thus, complementary information on the evolution of electron correlations, influenced by the rich electronic phases in condensed matter systems, can be extracted through the study of two-particle charge response., Comment: 6 Figures

The ability to create superlattices in van der Waals (vdW) heterostructures via moir\'e interference heralded a new era in the science and technology of two-dimensional materials. Through precise control of the twist angle, flat bands and strongly correlated phases have been engineered. The precise twisting of vdW layers is in some sense a bottom-up approach--a single parameter can dial in a wide range of periodic structures. Here, we describe a top-down approach to engineering nanoscale potentials in vdW layers using a buried programmable ferroelectric layer. Ultra-low-voltage electron beam lithography (ULV-EBL) is used to program ferroelectric domains in a ferroelectric Al_{1-x}B_{x}N thin film through a graphene/hexagonal boron nitride (hBN) heterostructure that is transferred on top. We demonstrate ferroelectric field effects by creating a lateral p-n junction, and demonstrate spatial resolution down to 35 nm, limited by the resolution of our scanned probe characterization methods. This innovative, resist-free patterning method is predicted to achieve 10 nm resolution and enable arbitrary programming of vdW layers, opening a pathway to create new phases that are inaccessible by moir\'e techniques. The ability to "paint" different phases of matter on a single vdW "canvas" provides a wealth of new electronic and photonic functionalities., Comment: 9 pages, 4 figures and supplemental material

X-ray binaries (XRBs) often exhibit spectral residuals in the 0.5 to 2 keV range, known as the "1 keV residual/1 keV feature", with variable centroid and intensity across different systems. Yet a comprehensive scientific explanation of the variability of the 1 keV feature has remained largely elusive. In this paper, we explain for the first time the origin and variability of the 1 keV feature in XRBs using the spectral synthesis code \textsc{Cloudy}. We constructed line blends for the emission and absorption lines and study the variability of these blends with ionization parameters, temperature, and column density. We conducted a sample study involving five XRBs including two ultraluminous X-ray sources (ULXs): NGC 247 ULX-1, NGC 1313 X-1, a binary X-ray pulsar: Hercules X-1, and two typical low-mass X-ray binaries (LMXBs): Cygnus X-2, and Serpens X-1, providing a comprehensive explanation of the 1 keV feature observed across these targets., Comment: 22 pages, 12 figures, Submitted to MNRAS

One of the more complex tasks for researchers using HPC systems is performance monitoring and tuning of their applications. Developing a practice of continuous performance improvement, both for speed-up and efficient use of resources is essential to the long term success of both the HPC practitioner and the research project. Profiling tools provide a nice view of the performance of an application but often have a steep learning curve and rarely provide an easy to interpret view of resource utilization. Lower level tools such as top and htop provide a view of resource utilization for those familiar and comfortable with Linux but a barrier for newer HPC practitioners. To expand the existing profiling and job monitoring options, the MIT Lincoln Laboratory Supercomputing Center created LLoad, a tool that captures a snapshot of the resources being used by a job on a per user basis. LLload is a tool built from standard HPC tools that provides an easy way for a researcher to track resource usage of active jobs. We explain how the tool was designed and implemented and provide insight into how it is used to aid new researchers in developing their performance monitoring skills as well as guide researchers in their resource requests.

In the fabrication of optical fibres, the viscosity of the glass varies dramatically with temperature so that heat transfer plays an important role in the deformation of the fibre geometry. Surprisingly, for quasi-steady drawing, with measurement of pulling tension, the applied heat can be adjusted to control the tension and temperature modelling is not needed. However, when pulling tension is not measured, a coupled heat and fluid flow model is needed to determine the inputs required for a desired output. In the fast process of drawing a preform to a fibre, heat advection dominates conduction so that heat conduction may be neglected. By contrast, in the slow process of extruding a preform, heat conduction is important. This means that solving the coupled flow and temperature modelling is essential for prediction of preform geometry. In this paper we derive such a model that incorporates heat conduction for the extensional flow of fibres. The dramatic variations in viscosity with temperature means that this problem is extremely challenging to solve via standard numerical techniques and we therefore develop a novel finite-difference numerical solution method that proves to be highly robust. We use this method to show that conduction significantly affects the size of internal holes at the exit of the device., Comment: 32 pages, 6 figures, 1 table

Large language models (LLMs) are capable of producing high quality information at unprecedented rates. As these models continue to entrench themselves in society, the content they produce will become increasingly pervasive in databases that are, in turn, incorporated into the pre-training data, fine-tuning data, retrieval data, etc. of other language models. In this paper we formalize the idea of a communication network of LLMs and introduce a method for representing the perspective of individual models within a collection of LLMs. Given these tools we systematically study information diffusion in the communication network of LLMs in various simulated settings.