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1,037 results on '"Hayden, Frederick G"'

1. Heterogeneity of treatment effect of interferon-β1b and lopinavir–ritonavir in patients with Middle East respiratory syndrome by cytokine levels

Author

Arabi, Yaseen M., Asiri, Ayed Y., Assiri, Abdullah M., Abdullah, Mashan L., Aljami, Haya A., Balkhy, Hanan H., Al Jeraisy, Majed, Mandourah, Yasser, AlJohani, Sameera, Al Harbi, Shmeylan, Jokhdar, Hani A. Aziz, Deeb, Ahmad M., Memish, Ziad A., Jose, Jesna, Ghazal, Sameeh, Al Faraj, Sarah, Al Mekhlafi, Ghaleb A., Sherbeeni, Nisreen Murad, Elzein, Fatehi Elnour, Hayden, Frederick G., Fowler, Robert A., AlMutairi, Badriah M., Al-Dawood, Abdulaziz, and Alharbi, Naif Khalaf

Published
2022
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2. Oral Favipiravir Exposure and Pharmacodynamic Effects in Adult Outpatients With Acute Influenza.

Author

Hayden, Frederick G, Lenk, Robert P, Epstein, Carol, and Kang, Lih Lisa

Subjects
*CLINICAL trials, *INFLUENZA, *PHARMACOKINETICS, *PHARMACODYNAMICS, *TITERS
Abstract

Background The pharmacokinetics of oral favipiravir and the relationships of plasma concentrations to antiviral effects are incompletely studied in influenza. Methods Serial plasma samples were collected from adults with uncomplicated influenza who were randomized to favipiravir (1800 mg twice a day on day 1, 800 mg twice a day on days 2 to 5; n = 827) or placebo (n = 419) in 2 phase 3 trials. Post hoc analyses assessed the frequency of reaching an average minimum concentration (Cmin) ≥20 µg/mL, its association with antiviral efficacy, and factors associated with reduced favipiravir exposure. Results Wide interindividual variability existed in favipiravir concentrations, and this regimen failed to reach an average Cmin > 20 µg/mL in 41%–43% of participants. Those attaining this threshold showed greater reductions in nasopharyngeal infectious virus titers on treatment days 2 and 3 and lower viral titer area under the curve compared to those who did not. Those with average Cmin <20 µg/mL had over 2-fold higher mean ratios of the metabolite T-705M1 to favipiravir, consistent with greater metabolism, and were more likely to weigh > 80 kg (61.5%–64%). Conclusions Higher favipiravir levels with average Cmin > 20 µg/mL were associated with larger antiviral effects and more rapid illness alleviation compared to placebo and to favipiravir recipients with lower average Cmin values in uncomplicated influenza. Clinical Trials Registration. NCT1068912 and NCT01728753. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Comparative Effectiveness of Baloxavir Marboxil and Oseltamivir Treatment in Reducing Household Transmission of Influenza: A Post Hoc Analysis of the BLOCKSTONE Trial.

Author

Ikematsu, Hideyuki, Baba, Takamichi, Saito, Masaya M., Kinoshita, Masahiro, Miyazawa, Shogo, Hata, Ayano, Nakano, Saki, Kitanishi, Yoshitake, and Hayden, Frederick G.

Subjects
INFLUENZA, HOUSEHOLDS, POISSON regression, OSELTAMIVIR, VACCINATION status, SWINE influenza
Abstract

Background: The transmission of influenza virus in households, especially by children, is a major route of infection. Prior studies suggest that timely antiviral treatment of ill cases may reduce infection in household contacts. The aim of the study was to compare the effects of oseltamivir (OTV) and baloxavir marboxil (BXM) treatment of index cases on the secondary attack rate (SAR) of influenza within household. Methods: A post hoc analysis was done in BLOCKSTONE trial—a placebo‐controlled, double‐blinded post‐exposure prophylaxis of BXM. Data were derived from the laboratory‐confirmed index cases' household contacts who received placebo in the trial and also from household members who did not participate in the trial but completed illness questionnaires. To assess the SAR of household members, multivariate analyses adjusted for factors including age, vaccination status, and household size were performed and compared between contacts of index cases treated with BXM or OTV. Results: In total, 185 index cases (116 treated with BXM and 69 treated with OTV) and 410 household contacts (201 from trial, 209 by questionnaire) were included. The Poisson regression modeling showed that the SAR in household contacts of index cases treated with BXM and OTV was 10.8% and 18.5%, respectively; the adjusted relative reduction in SAR was 41.8% (95% confidence interval: 1.0%–65.7%, p = 0.0456) greater with BXM than OTV. Similar reductions were found in contacts from the trial and those included by questionnaire. Conclusion: BXM treatment of index cases appeared to result in a greater reduction in secondary household transmission than OTV treatment. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Infectious Diseases Society of America and Gain-of-Function Experiments With Pathogens Having Pandemic Potential

Author

Frank, Gregory M, Adalja, Amesh, Barbour, Alan, Casadevall, Arturo, Dormitzer, Philip R, Duchin, Jeff, Hayden, Frederick G, Hirsch, Martin S, Hynes, Noreen A, Lipsitch, Marc, Pavia, Andrew T, and Relman, David A

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Good Health and Well Being, Animals, Biomedical Research, Humans, Pandemics, RNA Virus Infections, Research Design, gain-of-function, potential pandemic pathogens, influenza, science policy, health policy, Biological Sciences, Medical and Health Sciences, Microbiology, Biological sciences, Biomedical and clinical sciences, Health sciences
Published
2016

6. Critical care management of adults with community-acquired severe respiratory viral infection

Author

Arabi, Yaseen M., Fowler, Robert, and Hayden, Frederick G.

Subjects
Medical research -- Usage, Medicine, Experimental -- Usage, Adults -- Usage, Severe acute respiratory syndrome -- Usage, Coronaviruses -- Usage, Health care industry, Infectious Diseases Society of America
Abstract

With the expanding use of molecular assays, viral pathogens are increasingly recognized among critically ill adult patients with community-acquired severe respiratory illness; studies have detected respiratory viral infections (RVIs) in 17-53% of such patients. In addition, novel pathogens including zoonotic coronaviruses like the agents causing Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS) and the 2019 novel coronavirus (2019 nCoV) are still being identified. Patients with severe RVIs requiring ICU care present typically with hypoxemic respiratory failure. Oseltamivir is the most widely used neuraminidase inhibitor for treatment of influenza; data suggest that early use is associated with reduced mortality in critically ill patients with influenza. At present, there are no antiviral therapies of proven efficacy for other severe RVIs. Several adjunctive pharmacologic interventions have been studied for their immunomodulatory effects, including macrolides, corticosteroids, cyclooxygenase-2 inhibitors, sirolimus, statins, anti-influenza immune plasma, and vitamin C, but none is recommended at present in severe RVIs. Evidence-based supportive care is the mainstay for management of severe respiratory viral infection. Non-invasive ventilation in patients with severe RVI causing acute hypoxemic respiratory failure and pneumonia is associated with a high likelihood of transition to invasive ventilation. Limited existing knowledge highlights the need for data regarding supportive care and adjunctive pharmacologic therapy that is specific for critically ill patients with severe RVI. There is a need for more pragmatic and efficient designs to test different therapeutics both individually and in combination., Author(s): Yaseen M. Arabi [sup.1] [sup.2] [sup.3], Robert Fowler [sup.4] [sup.5] [sup.6], Frederick G. Hayden [sup.7] Author Affiliations: (1) grid.412149.b, 0000 0004 0608 0662, College of Medicine, King Saud Bin [...]

Published
2020
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8. Macrolides in critically ill patients with Middle East Respiratory Syndrome

Author

Arabi, Yaseen M., Deeb, Ahmad M., Al-Hameed, Fahad, Mandourah, Yasser, Almekhlafi, Ghaleb A., Sindi, Anees A., Al-Omari, Awad, Shalhoub, Sarah, Mady, Ahmed, Alraddadi, Basem, Almotairi, Abdullah, Al Khatib, Kasim, Abdulmomen, Ahmed, Qushmaq, Ismael, Solaiman, Othman, Al-Aithan, Abdulsalam M., Al-Raddadi, Rajaa, Ragab, Ahmad, Al Harthy, Abdulrahman, Kharaba, Ayman, Jose, Jesna, Dabbagh, Tarek, Fowler, Robert A., Balkhy, Hanan H., Merson, Laura, and Hayden, Frederick G.

Published
2019
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10. Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update

Author

Alhazzani, Waleed, Evans, Laura, Alshamsi, Fayez, Møller, Morten Hylander, Ostermann, Marlies, Prescott, Hallie C., Arabi, Yaseen M., Loeb, Mark, Ng Gong, Michelle, Fan, Eddy, Oczkowski, Simon, Levy, Mitchell M., Derde, Lennie, Dzierba, Amy, Du, Bin, Machado, Flavia, Wunsch, Hannah, Crowther, Mark, Cecconi, Maurizio, Koh, Younsuck, Burry, Lisa, Chertow, Daniel S., Szczeklik, Wojciech, Belley-Cote, Emilie, Greco, Massimiliano, Bala, Malgorzata, Zarychanski, Ryan, Kesecioglu, Jozef, McGeer, Allison, Mermel, Leonard, Mammen, Manoj J., Nainan Myatra, Sheila, Arrington, Amy, Kleinpell, Ruth, Citerio, Giuseppe, Lewis, Kimberley, Bridges, Elizabeth, Memish, Ziad A., Hammond, Naomi, Hayden, Frederick G., Alshahrani, Muhammed, Al Duhailib, Zainab, Martin, Greg S., Kaplan, Lewis J., Coopersmith, Craig M., Antonelli, Massimo, and Rhodes, Andrew

Published
2021
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12. Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19)

Author

Alhazzani, Waleed, Møller, Morten Hylander, Arabi, Yaseen M., Loeb, Mark, Gong, Michelle Ng, Fan, Eddy, Oczkowski, Simon, Levy, Mitchell M., Derde, Lennie, Dzierba, Amy, Du, Bin, Aboodi, Michael, Wunsch, Hannah, Cecconi, Maurizio, Koh, Younsuck, Chertow, Daniel S., Maitland, Kathryn, Alshamsi, Fayez, Belley-Cote, Emilie, Greco, Massimiliano, Laundy, Matthew, Morgan, Jill S., Kesecioglu, Jozef, McGeer, Allison, Mermel, Leonard, Mammen, Manoj J., Alexander, Paul E., Arrington, Amy, Centofanti, John E., Citerio, Giuseppe, Baw, Bandar, Memish, Ziad A., Hammond, Naomi, Hayden, Frederick G., Evans, Laura, and Rhodes, Andrew

Published
2020
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14. Seasonal Influenza in Adults and Children—Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management: Clinical Practice Guidelines of the Infectious Diseases Society of America

Author

Harper, Scott A, Bradley, John S, Englund, Janet A, File, Thomas M, Gravenstein, Stefan, Hayden, Frederick G, McGeer, Allison J, Neuzil, Kathleen M, Pavia, Andrew T, Tapper, Michael L, Uyeki, Timothy M, and Zimmerman, Richard K

Subjects
Infectious Diseases, Vaccine Related, Emerging Infectious Diseases, Influenza, Pneumonia & Influenza, Prevention, Clinical Research, Biodefense, Infection, Good Health and Well Being, Adult, Antiviral Agents, Chemoprevention, Child, Disease Management, Disease Outbreaks, Guideline Adherence, Humans, Influenza, Human, Risk Factors, Seasons, Expert Panel of the Infectious Diseases Society of America, Biological Sciences, Medical and Health Sciences, Microbiology
Abstract

Guidelines for the treatment of persons with influenza virus infection were prepared by an Expert Panel of the Infectious Diseases Society of America. The evidence-based guidelines encompass diagnostic issues, treatment and chemoprophylaxis with antiviral medications, and issues related to institutional outbreak management for seasonal (interpandemic) influenza. They are intended for use by physicians in all medical specialties with direct patient care, because influenza virus infection is common in communities during influenza season and may be encountered by practitioners caring for a wide variety of patients.

Published
2009

15. Evaluation of the efficacy and safety of intravenous remdesivir in adult patients with severe COVID-19: study protocol for a phase 3 randomized, double-blind, placebo-controlled, multicentre trial

Author

Wang, Yeming, Zhou, Fei, Zhang, Dingyu, Zhao, Jianping, Du, Ronghui, Hu, Yi, Cheng, Zhenshun, Gao, Ling, Jin, Yang, Luo, Guangwei, Fu, Shouzhi, Lu, Qiaofa, Du, Guanhua, Wang, Ke, Lu, Yang, Fan, Guohui, Zhang, Yi, Liu, Ying, Ruan, Shunan, Liu, Wen, Jaki, Thomas, Hayden, Frederick G., Horby, Peter W., Cao, Bin, and Wang, Chen

Published
2020
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18. Clinical and Economic Impact of COVID-19 on Agricultural Workers, Guatemala1

Author

Olson, Daniel, primary, Calvimontes, Diva M., additional, Lamb, Molly M., additional, Guzman, Gerber, additional, Barrios, Edgar, additional, Chacon, Andrea, additional, Rojop, Neudy, additional, Arias, Kareen, additional, Gomez, Melissa, additional, Bolanos, Guillermo A., additional, Monzon, Jose, additional, Chard, Anna N., additional, Iwamoto, Chelsea, additional, Duca, Lindsey M., additional, Vuong, Nga, additional, Fineman, Melissa, additional, Lesteberg, Kelsey, additional, Beckham, David, additional, Santiago, Mario L., additional, Quicke, Kendra, additional, Ebel, Gregory, additional, Gutierrez, Emily Zielinski, additional, Azziz-Baumgartner, Eduardo, additional, Hayden, Frederick G., additional, Mansour, Hani, additional, Edwards, Kathryn, additional, Newman, Lee S., additional, and Asturias, Edwin J., additional

Published
2023
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21. Corticosteroid Therapy for Critically Ill Patients with Middle East Respiratory Syndrome

Author

Arabi, Yaseen M., Mandourah, Yasser, Al-Hameed, Fahad, Sindi, Anees A., Almekhlafi, Ghaleb A., Hussein, Mohamed A., Jose, Jesna, Pinto, Ruxandra, Al-Omari, Awad, Kharaba, Ayman, Almotairi, Abdullah, Al Khatib, Kasim, Alraddadi, Basem, Shalhoub, Sarah, Abdulmomen, Ahmed, Qushmaq, Ismael, Mady, Ahmed, Solaiman, Othman, Al-Aithan, Abdulsalam M., Al-Raddadi, Rajaa, Ragab, Ahmed, Balkhy, Hanan H., Al Harthy, Abdulrahman, Deeb, Ahmad M., Al Mutairi, Hanan, Al-Dawood, Abdulaziz, Merson, Laura, Hayden, Frederick G., and Fowler, Robert A.

Published
2018
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23. List of Contributors

Author

Abrahamian, Fredrick M., primary, Aldape, Michael J., additional, Aldasoro, Edelweiss, additional, Allen, Upton D., additional, Al-Sum, Hythem, additional, Anadkat, Milan J., additional, Anders, Katherine, additional, Angelakis, Emmanouil, additional, Angus, Brian John, additional, Antoniadou, Anastasia, additional, Arena, Fabio, additional, Arends, Joop E., additional, Arribas, Jose R., additional, Artenstein, Andrew W., additional, Atherton, John C., additional, Aucott, John N., additional, Aw, Tar-Ching, additional, Babcock, Hilary M., additional, Bailey, Robin, additional, Bailey, Thomas C., additional, Banks, Adam Z., additional, Barillo, David J., additional, Barrette, Ernie-Paul, additional, Bauer, Martijn P., additional, Bayston, Roger, additional, Beard, C. Ben, additional, Beardsley, Justin, additional, Beeching, Nick J., additional, Bégué, Rodolfo E., additional, Beldi, Guido, additional, Benson, Constance A., additional, Berbari, Elie F., additional, Berenger, Jean-Michel, additional, Berger, Christoph, additional, Bernardino, Jose I., additional, Bille, Jacques, additional, Billioux, Alexander C., additional, Bitnun, Ari, additional, Blair, Iain, additional, Blanche, Stéphane, additional, Bleck, Thomas P., additional, Bleeker-Rovers, Chantal P., additional, Bleijenberg, Gijs, additional, Bloch, Karen C., additional, Blum, Johannes, additional, Blumberg, Emily A., additional, Bonomo, Robert A., additional, Bonten, Marc J.M., additional, Bourayou, Rafik, additional, Bouza, Emilio, additional, Brandt, K. Ashley, additional, Bretelle, Florence, additional, Brisse, Sylvain, additional, Britton, Warwick J., additional, Brook, Itzhak, additional, Brouwer, Matthijs C., additional, Browne, Sarah K., additional, Bryant, Amy E., additional, Bühler, Silja, additional, Bulger, Eileen M., additional, Buller, R. Mark L., additional, Burke, Leah A., additional, Burri, Christian, additional, Butler, Marcus W., additional, Calandra, Thierry, additional, Calfee, David P., additional, Calvo-Cano, Antonia, additional, Cameron, D. William, additional, Carcillo, Joseph A., additional, Carson, Gail, additional, Chambers, Stephen T., additional, Charrel, Remi N., additional, Nguyen, Vinh Chau Van, additional, Chevaliez, Stéphane, additional, Chiller, Tom M., additional, Christaki, Eirini, additional, Chung, Kevin K., additional, Clifford, David B., additional, Clumeck, Nathan, additional, Cohen, Jonathan, additional, Collinge, John, additional, Conlon, Christopher P., additional, Conrad, Curdin, additional, Cooke, Fiona J., additional, Cope, Jennifer Rittenhouse, additional, Corey, G. Ralph, additional, Cross, John H., additional, Cunha, Burke A., additional, Cunha, Cheston B., additional, D'Journo, Benoit, additional, Daikos, George L., additional, Daniels, Johannes M.A., additional, Davidson, Robert N., additional, Day, Nicholas P.J., additional, De Cock, Kevin M., additional, de Silva, Thushan I., additional, de Vries, Henry J.C., additional, de Wit, Stéphane, additional, Delaloye, Julie, additional, Denning, David W., additional, Dennis, David T., additional, Dhanireddy, Shireesha, additional, Dielubanza, Elodi J., additional, Diemert, David J., additional, Doganay, Mehmet, additional, Doherty, Tom, additional, Dolecek, Christiane, additional, Dondorp, Arjen M., additional, Douglas, Abby, additional, Drancourt, Michel, additional, Dubourg, Grégory, additional, Dudley, Michael N., additional, Durand, Guillaume, additional, Eckhardt, Benjamin J., additional, Efstratiou, Androulla, additional, Ekkelenkamp, Miquel B., additional, Eranki, Ambika, additional, Erdem, Hakan, additional, Escota, Gerome V., additional, Evans, Heather L., additional, Eziefula, Alice Chijioke, additional, Fenollar, Florence, additional, Fenwick, Alan, additional, Fierer, Joshua, additional, Finch, Roger G., additional, Fleckenstein, James M., additional, Forstner, Christina, additional, Foschi, Federico, additional, Fournier, Pierre-Edouard, additional, French, Martyn A., additional, Gage, Kenneth L., additional, Garcia, Lynne S., additional, Gascon, Joaquim, additional, Gastañaduy, Arturo S., additional, Gautret, Philippe, additional, Geisler, William M., additional, Ghanem, Khalil G., additional, Giani, Tommaso, additional, Giannella, Maddalena, additional, Gilliam, Bruce L., additional, Gilliet, Michel, additional, Glaser, Carol A., additional, Glupczynski, Youri, additional, Gnann, John W., additional, Goldstein, Ellie J.C., additional, Gottstein, Bruno, additional, Gouriet, Frederique, additional, Gravitt, Patti E., additional, Green, Michael D., additional, Green, Stephen T., additional, Groll, Andreas H., additional, Gulick, Roy M., additional, Gupta, Arjun, additional, Habib, Gilbert, additional, Harbarth, Stephan, additional, Harris, Marianne, additional, Hayden, Frederick G., additional, Hetem, David J., additional, Hill, Philip C., additional, Hirschel, Bernard, additional, Hodowanec, Aimee C., additional, Hoffart, Louis, additional, Hoffmann, Christian, additional, Holland, Steven M., additional, Horby, Peter W., additional, Horne, David J., additional, Hraiech, Sami, additional, Hull, Mark W., additional, Huttner, Angela, additional, Ingram, Richard J.M., additional, Islam, Jasmin, additional, Ison, Michael G., additional, James, Scott H., additional, Jenkins, Claire, additional, Jenkins, Stephen G., additional, Jensen, Jørgen Skov, additional, Johnston, Christine, additional, Jones, Theodore B., additional, Jordan, Stephen J., additional, Julian, Kathleen G., additional, Kato, Yasuyuki, additional, Kauffman, Carol A., additional, Kaye, Keith S., additional, Keane, Michael P., additional, Keeney, James, additional, Kelly, Paul, additional, Kent, Stephen J., additional, Kern, Winfried V., additional, Keynan, Yoav, additional, Kim, Andrea A., additional, Koné-Paut, Isabelle, additional, Kosmidis, Chris, additional, Kroes, Aloys C.M., additional, Kroon, Frank P., additional, Ksiazek, Thomas G., additional, Kuhlmann, F. Matthew, additional, Kuijper, Ed J., additional, Kwon, Jennie H., additional, Kyei, George B., additional, Lacombe, Karine, additional, Lagacé-Wiens, Philippe, additional, Lagier, Jean-Christophe, additional, Lamagni, Theresa, additional, Landraud, Luce, additional, Lanternier, Fanny, additional, LaPlante, Kerry L., additional, Lawn, Stephen D., additional, Lawrence, Steven J., additional, Leblebicioglu, Hakan, additional, Lee, Nelson, additional, Leggett, James E., additional, Lehours, Philippe, additional, Levy, Pierre-Yves, additional, Leyh, Rainer G., additional, Lillis, Rebecca A., additional, Limmathurotsakul, Direk, additional, Lin, Jennifer, additional, Lindquist, H.D. Alan, additional, Lipsky, Benjamin A., additional, Liscynesky, Christina, additional, Looney, David, additional, Lortholary, Olivier, additional, Lowy, Franklin D., additional, Luft, Benjamin J., additional, Mackowiak, Philip A., additional, MacPherson, Paul A., additional, Maghraoui-Slim, Valérie, additional, Mallon, Patrick W., additional, Mangino, Julie E., additional, Manuel, Oriol, additional, Marchetti, Oscar, additional, Marks, Kristen M., additional, Marr, Kieren A., additional, Marrazzo, Jeanne, additional, Marschall, Jonas, additional, Martin, David H., additional, Matonti, Frédéric, additional, Matulewicz, Richard S., additional, Mayer, Kenneth H., additional, McCulloh, Russell J., additional, McGready, Rose, additional, Mdodo, Rennatus, additional, Mead, Simon, additional, Mégraud, Francis, additional, Meintjes, Graeme, additional, Metcalf, Sarah C., additional, Michaels, Marian G., additional, Migliori, Giovanni Battista, additional, Miles, Michael A., additional, Miller, Alastair, additional, Mimiaga, Matthew J., additional, Mingeot-Leclercq, Marie-Paule, additional, Misch, Elizabeth Ann, additional, Mitreva, Makedonka, additional, Montaner, Julio S.G., additional, Moore, Caroline B., additional, Muñoz, Patricia, additional, Muñoz, Jose, additional, Murray, Clinton K., additional, Musso, Didier, additional, Mutengo, Mable, additional, Mutizwa, Misha M., additional, Naber, Kurt G., additional, Natarajan, Pavithra, additional, Neme, Santiago, additional, Newton, Paul N., additional, Nichols, Ronald A., additional, Nicolle, Lindsay E., additional, Nosten, François, additional, Notarangelo, Luigi D., additional, Nutman, Thomas B., additional, Nyirjesy, Paul, additional, O'Connell, P. Ronan, additional, Opal, Steven M., additional, Ormerod, L. Peter, additional, Osmon, Douglas R., additional, Pankert, Marie Boulze, additional, Pantaleo, Giuseppe, additional, Papazian, Laurent, additional, Parente, Diane M., additional, Parola, Philippe, additional, Parsaei, Shadi, additional, Pascual, Manuel A., additional, Patel, Rupa, additional, Patrozou, Eleni, additional, Pawlotsky, Jean-Michel, additional, Peacock, Sharon J., additional, Pechère, Jean-Claude, additional, Pelegrin, Ivan, additional, Peters, Barry S., additional, Peters, Edgar J.G., additional, Petersen, Jeannine M., additional, Petersen, Lyle R., additional, Petraitis, Vidmantas, additional, Pham, Luu-Ly, additional, Picado, Albert, additional, Pilatz, Adrian, additional, Pilmis, Benoit, additional, Pinazo, María-Jesús, additional, Pletz, Mathias W., additional, Pogue, Jason M., additional, Polgreen, Evelyn L., additional, Polgreen, Philip M., additional, Posfay-Barbe, Klara M., additional, Powderly, William G., additional, Presti, Rachel, additional, Prod'hom, Guy, additional, Puolakkainen, Mirja, additional, Quinn, Thomas C., additional, Raoult, Didier, additional, Razonable, Raymund R., additional, Read, Robert C., additional, Redfield, Robert R., additional, Rentenaar, Rob J., additional, Reynolds, Steven J., additional, Ribi, Camillo, additional, Richardson, Malcolm D., additional, Ritter, Michele L., additional, Roch, Antoine, additional, Rockstroh, Jürgen Kurt, additional, Rojek, Amanda, additional, Romero, José R., additional, Rooijakkers, Suzan H.M., additional, Rosenbluth, Daniel, additional, Rosenzweig, Sergio D., additional, Rossolini, Gian Maria, additional, Rubinstein, Ethan, additional, Ryan, Greg, additional, Safren, Steven A., additional, Sahasrabuddhe, Vikrant V., additional, Saikku, Pekka A.I., additional, Sajadi, Mohammad M., additional, Salvaggio, Michelle R., additional, Santos, Carlos A.Q., additional, Satlin, Michael J., additional, Schaeffer, Anthony J., additional, Schimmer, Christoph, additional, Schooley, Robert T., additional, Schumacher, Richard F., additional, Sha, Beverly E., additional, Shapiro, Daniel S., additional, Sheehan, Gerard, additional, Shlaes, David M., additional, Shoham, Shmuel, additional, Simmons, Cameron P., additional, Simon, Dennis W., additional, Simon, Matthew S., additional, Simonsen, Kari A., additional, Slack, Mary P.E., additional, Smith, Tyrel T., additional, Sobel, Jack D., additional, Souli, Maria, additional, Sridhar, Shruti, additional, Steckelberg, James M., additional, Stevens, Dennis L., additional, Strah, Heather, additional, Sturm, A. Willem, additional, Sungkanuparph, Somnuek, additional, Tabrizi, Sarah J., additional, Tacconelli, Evelina, additional, Tan, Chen Sabrina, additional, Taplitz, Randy A., additional, Thomas, Guillemette, additional, Thomas, Lora D., additional, Thuny, Franck, additional, Thwaites, Guy, additional, Tissot, Frederic, additional, Tønjum, Tone, additional, Torriani, Francesca J., additional, Toso, Christian, additional, Tulkens, Paul M., additional, Tunkel, Allan R., additional, Turner, Claire E., additional, Ustianowski, Andrew P., additional, van Bambeke, Françoise, additional, van Crevel, Reinout, additional, van de Beek, Diederik, additional, van Delden, Christian, additional, van der Eerden, Menno M., additional, van der Meer, Jos W.M., additional, van der Poll, Tom, additional, van Ingen, Jakko, additional, van Putten, Jos, additional, Vaudaux, Bernard P., additional, Vermund, Sten H., additional, Viscidi, Raphael P., additional, Visvanathan, Kumar, additional, Visvesvara, Govinda S., additional, von Seidlein, Lorenz, additional, Wagenlehner, Florian M.E., additional, Wald, Anna, additional, Walsh, Thomas J., additional, Warhurst, David C., additional, Warnock, David W., additional, Warrell, David A., additional, Warrell, Mary J., additional, Warris, Adilia, additional, Watkins, Richard R., additional, Weatherall, David J., additional, Weber, Rainer, additional, Weidner, Wolfgang, additional, White, Jonathan R., additional, White, Peter J., additional, Whitehorn, James, additional, Whitley, Richard J., additional, Whitty, Christopher J.M., additional, Wiersinga, Willem Joost, additional, Wilcox, Mark H., additional, Williams, Thomas N., additional, Wilson, Cara C., additional, Wilson, Mary Elizabeth, additional, Wisplinghoff, Hilmar, additional, Wood, Robin, additional, Wunderink, Richard G., additional, Wyles, David, additional, Yang, Zhi-Tao, additional, Yoder, Jonathan S., additional, Zaidi, Najam A., additional, Zimmer, Andrea J., additional, Zuckerman, Jane N., additional, and Zumla, Alimuddin, additional

Published
2017
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24. Feasibility of using convalescent plasma immunotherapy for MERS-CoV infection, Saudi Arabia

Author

Arabi, Yaseen M., Hajeer, Ali H., Luke, Thomas, Raviprakash, Kanakatte, Balkhy, Hanan, Johani, Sameera, Dawood, Abdulaziz Al-, Qahtani, Saad Al-, Omari, Awad Al-, Hameed, Fahad Al-, Hayden, Frederick G., Fowler, Robert, Bouchama, Abderrezak, Shindo, Nahoko, Khairy, Khalid Al-, Carson, Gail, Taha, Yusri, Sadat, Musharaf, and Alahmadi, Mashail

Subjects
Mortality -- Research -- Risk factors -- Saudi Arabia, Middle East respiratory syndrome -- Research -- Care and treatment -- Identification and classification, Immunotherapy -- Health aspects -- Usage, Health
Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV) was initially identified in September 2012 when a patient in Saudi Arabia with a severe, acute respiratory infection and acute renal failure died (1). [...]

Published
2016
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25. Feasibility, safety, clinical, and laboratory effects of convalescent plasma therapy for patients with Middle East respiratory syndrome coronavirus infection: a study protocol

Author

Arabi, Yaseen, Balkhy, Hanan, Hajeer, Ali H., Bouchama, Abderrezak, Hayden, Frederick G., Al-Omari, Awad, Al-Hameed, Fahad M., Taha, Yusri, Shindo, Nahoko, Whitehead, John, Merson, Laura, AlJohani, Sameera, Al-Khairy, Khalid, Carson, Gail, Luke, Thomas C., Hensley, Lisa, Al-Dawood, Abdulaziz, Al-Qahtani, Saad, Modjarrad, Kayvon, Sadat, Musharaf, Rohde, Gernot, Leport, Catherine, and Fowler, Robert

Published
2015
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28. Critically Ill Patients With the Middle East Respiratory Syndrome: A Multicenter Retrospective Cohort Study

Author

Arabi, Yaseen M., Al-Omari, Awad, Mandourah, Yasser, Al-Hameed, Fahad, Sindi, Anees A., Alraddadi, Basem, Shalhoub, Sarah, Almotairi, Abdullah, Al Khatib, Kasim, Abdulmomen, Ahmed, Qushmaq, Ismael, Mady, Ahmed, Solaiman, Othman, Al-Aithan, Abdulsalam M., Al-Raddadi, Rajaa, Ragab, Ahmed, Al Mekhlafi, Ghaleb. A., Al Harthy, Abdulrahman, Kharaba, Ayman, Ahmadi, Mashael Al, Sadat, Musharaf, Mutairi, Hanan Al, Qasim, Eman Al, Jose, Jesna, Nasim, Maliha, Al-Dawood, Abdulaziz, Merson, Laura, Fowler, Robert, Hayden, Frederick G., and Balkhy, Hanan H.

Published
2017
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29. Middle East Respiratory Syndrome

Author

Arabi, Yaseen M., Balkhy, Hanan H., Hayden, Frederick G., Bouchama, Abderrezak, Luke, Thomas, Baillie, Kenneth J., Al-Omari, Awad, Hajeer, Ali H., Senga, Mikiko, Denison, Mark R., Nguyen-Van-Tam, Jonathan S., Shindo, Nahoko, Bermingham, Alison, Chappell, James D., Van Kerkhove, Maria D., and Fowler, Robert A.

Published
2017
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34. Clinical and Economic Impact of COVID-19 on Plantation Workers: Preliminary Results from the Guatemala Agricultural Workers and Respiratory Illness Impact (AGRI) Study

Author

Olson, Daniel, primary, Calvimontes, Diva M., additional, Lamb, Molly M., additional, Guzman, Gerber, additional, Barrios, Edgar, additional, Chacon, Andrea, additional, Rojop, Neudy, additional, Arias, Kareen, additional, Gomez, Melissa, additional, Bolanos, Guillermo Antonio, additional, Monzon, Jose, additional, Chard, Anna N., additional, Iwamoto, Chelsea, additional, Duca, Lindsey M., additional, Vuong, Nga, additional, Fineman, Melissa, additional, Lesteberg, Kelsey, additional, Beckham, David, additional, Santiago, Mario L., additional, Quicke, Kendra, additional, Ebel, Gregory, additional, Gutierrez, Emily Zielinski, additional, Azziz-Baumgartner, Eduardo, additional, Hayden, Frederick G., additional, Mansour, Hani, additional, Edwards, Kathryn, additional, Newman, Lee S., additional, and Asturias, Edwin J., additional

Published
2022
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39. Comparison of the Safety and Immunogenicity of 2 Respiratory Syncytial Virus (RSV) Vaccines—Nonadjuvanted Vaccine or Vaccine Adjuvanted with Alum—Given Concomitantly with Influenza Vaccine to High-Risk Elderly Individuals

Author

Falsey, Ann R., Walsh, Edward E., Capellan, Jose, Gravenstein, Stefan, Zambon, Maria, Yau, Eddy, Gorse, Geoffrey J., Edelman, Robert, Hayden, Frederick G., McElhaney, Janet E., Neuzil, Kathleen M., Nichol, Kristen L., Simões, Eric A. F., Wright, Peter F., and Sales, Valérie M.-P.

Published
2008
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