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991 results on '"Hatanaka, Takeshi"'

1. Constraint-Driven Multi-USV Coverage Path Generation for Aquatic Environmental Monitoring

Author

Toyomoto, Yo, Oshima, Toshiyuki, Oishi, Kosei, Maestre, José M., and Hatanaka, Takeshi

Subjects
Electrical Engineering and Systems Science - Systems and Control
Abstract

In this article, we address aquatic environmental monitoring using a fleet of unmanned surface vehicles (USVs). Specifically, we develop an online path generator that provides either of circular or elliptic paths based on the real-time feedback so that the USVs efficiently sample the sensor data over given aquatic environment. To this end, we begin by formulating a novel online path generation problem for a group of Dubins vehicles in the form of cost minimization based on the formulation of persistent coverage control. We then transform the cost minimization into a constraint-based specification so that a prescribed performance level is certified. An online coverage path generator is then designed based on the so-called constraint-based control in order to meet the performance certificate together with additional constraints inherent in the parameters that specify the paths. It is also shown there that the present constraint-based approach allows one to drastically reduce the computational complexity stemming from combinations of binary variables corresponding to the turning directions of the USVs. The present coverage path generator is finally demonstrated through simulations and experiments on an original testbed of multiple USVs.

Published
2024

2. Angle-Aware Coverage with Camera Rotational Motion Control

Author

Lu, Zhiyuan, Hanif, Muhammad, Shimizu, Takumi, and Hatanaka, Takeshi

Subjects
Mathematics - Optimization and Control, Computer Science - Robotics
Abstract

This paper presents a novel control strategy for drone networks to improve the quality of 3D structures reconstructed from aerial images by drones. Unlike the existing coverage control strategies for this purpose, our proposed approach simultaneously controls both the camera orientation and drone translational motion, enabling more comprehensive perspectives and enhancing the map's overall quality. Subsequently, we present a novel problem formulation, including a new performance function to evaluate the drone positions and camera orientations. We then design a QP-based controller with a control barrier-like function for a constraint on the decay rate of the objective function. The present problem formulation poses a new challenge, requiring significantly greater computational efforts than the case involving only translational motion control. We approach this issue technologically, namely by introducing JAX, utilizing just-in-time (JIT) compilation and Graphical Processing Unit (GPU) acceleration. We finally conduct extensive verifications through simulation in ROS (Robot Operating System) and show the real-time feasibility of the controller and the superiority of the present controller to the conventional method., Comment: 17 pages, 8 figures, 2 tables

Published
2024

3. Net-Zero Energy House-oriented Linear Programming for the Sizing Problem of Photovoltaic Panels and Batteries

Author

Carnerero, A. Daniel, Tanaka, Taichi, Li, Mengmou, Hatanaka, Takeshi, Wasa, Yasuaki, Hirata, Kenji, Ushifusa, Yoshiaki, and Ida, Takanori

Subjects
Mathematics - Optimization and Control, Electrical Engineering and Systems Science - Systems and Control
Abstract

The global drive towards carbon neutrality has led to a significant increase in the number of power plants based on renewable energy sources (RES). Concurrently, numerous households are adopting RES to generate their own energy, aiming to decrease both electricity costs and carbon footprints. To support these users, many papers have been devoted to developing optimal investment strategies for residential energy systems. However, there is still a significant gap as these studies often neglect important aspects like carbon neutrality. For this reason, in this paper, we explore the concept of net-zero energy houses (ZEHs) -- houses designed to have an annual net energy consumption around zero -- by presenting a constrained optimization problem to find the optimal number of photovoltaic panels and the optimal size of the battery system for home integration. Solving this constrained optimization problem is difficult due to its nonconvex constraints. Nevertheless, by applying a series of transformations, we reveal that it is possible to find an equivalent linear programming (LP) problem which is computationally tractable. The attainment of ZEH can be tackled by introducing a single constraint in the optimization problem. Additionally, we propose a sharing economy approach to the investment problem, offering a strategy that could potentially reduce investment costs and facilitate the attainment of ZEH more efficiently. Finally, we apply the proposed frameworks to a neighborhood in Japan as a case study, demonstrating the potential for long-term ZEH attainment. The results show that, under the right incentive, users can achieve ZEH, reduce their electricity costs and have a minimal impact on the main grid., Comment: 13 pages, 13 figures, 5 tables

Published
2024
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4. Adverse Events as Potential Predictive Factors of Activity in Patients with Advanced HCC Treated with Atezolizumab Plus Bevacizumab

Author

Persano, Mara, Rimini, Margherita, Tada, Toshifumi, Suda, Goki, Shimose, Shigeo, Kudo, Masatoshi, Rossari, Federico, Yoo, Changhoon, Cheon, Jaekyung, Finkelmeier, Fabian, Lim, Ho Yeong, Presa, José, Masi, Gianluca, Bergamo, Francesca, Amadeo, Elisabeth, Vitiello, Francesco, Kumada, Takashi, Sakamoto, Naoya, Iwamoto, Hideki, Aoki, Tomoko, Chon, Hong Jae, Himmelsbach, Vera, Iavarone, Massimo Alberto, Cabibbo, Giuseppe, Montes, Margarida, Foschi, Francesco Giuseppe, Vivaldi, Caterina, Soldà, Caterina, Sho, Takuya, Niizeki, Takashi, Nishida, Naoshi, Steup, Christoph, Bruccoleri, Mariangela, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Hiraoka, Atsushi, Tada, Fujimasa, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Imai, Michitaka, Kosaka, Hisashi, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, Foti, Silvia, Camera, Silvia, Piscaglia, Fabio, Scartozzi, Mario, Cascinu, Stefano, and Casadei-Gardini, Andrea

Published
2024
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5. Stochastic Optimal Investment Strategy for Net-Zero Energy Houses

Author

Li, Mengmou, Tanaka, Taichi, Carnerero, A. Daniel, Wasa, Yasuaki, Hirata, Kenji, Fujisaki, Yasumasa, Ushifusa, Yoshiaki, and Hatanaka, Takeshi

Subjects
Economics - General Economics, Mathematics - Optimization and Control
Abstract

In this research, we investigate Net-Zero Energy Houses (ZEH), which harness regionally produced electricity from photovoltaic(PV) panels and fuel cells, integrating them into a local power system in pursuit of achieving carbon neutrality. This paper examines the impact of electricity sharing among users who are working towards attaining ZEH status through the integration of PV panels and battery storage devices. We propose two potential scenarios: the first assumes that all users individually invest in storage devices, hence minimizing their costs on a local level without energy sharing; the second envisions cost minimization through the collective use of a shared storage device, managed by a central manager. These two scenarios are formulated as a stochastic convex optimization and a cooperative game, respectively. To tackle the stochastic challenges posed by multiple random variables, we apply the Monte Carlo sample average approximation (SAA) to the problems. To demonstrate the practical applicability of these models, we implement the proposed scenarios in the Jono neighborhood in Kitakyushu, Japan., Comment: Submitted to IET Renewable Power Generation

Published
2023

6. Convergence Rate Bounds for the Mirror Descent Method: IQCs, Popov Criterion and Bregman Divergence

Author

Li, Mengmou, Laib, Khaled, Hatanaka, Takeshi, and Lestas, Ioannis

Subjects
Mathematics - Optimization and Control
Abstract

This paper presents a comprehensive convergence analysis for the mirror descent (MD) method, a widely used algorithm in convex optimization. The key feature of this algorithm is that it provides a generalization of classical gradient-based methods via the use of generalized distance-like functions, which are formulated using the Bregman divergence. Establishing convergence rate bounds for this algorithm is in general a non-trivial problem due to the lack of monotonicity properties in the composite nonlinearities involved. In this paper, we show that the Bregman divergence from the optimal solution, which is commonly used as a Lyapunov function for this algorithm, is a special case of Lyapunov functions that follow when the Popov criterion is applied to an appropriate reformulation of the MD dynamics. This is then used as a basis to construct an integral quadratic constraint (IQC) framework through which convergence rate bounds with reduced conservatism can be deduced. We also illustrate via examples that the convergence rate bounds derived can be tight., Comment: Accepted Version. arXiv admin note: substantial text overlap with arXiv:2204.00502

Published
2023

7. Safety and Efficacy of Lenvatinib in Very Old Patients with Unresectable Hepatocellular Carcinoma

Author

Camera, Silvia, Rimini, Margherita, Rossari, Federico, Tada, Toshifumi, Suda, Goki, Shimose, Shigeo, Kudo, Masatoshi, Yoo, Changhoon, Cheon, Jaekyung, Finkelmeier, Fabian, Lim, Ho Yeong, Presa, José, Masi, Gianluca, Bergamo, Francesca, Salani, Francesca, Marseglia, Mariarosaria, Amadeo, Elisabeth, Vitiello, Francesco, Kumada, Takashi, Sakamoto, Naoya, Iwamoto, Hideki, Aoki, Tomoko, Chon, Hong Jae, Himmelsbach, Vera, Iavarone, Massimo, Cabibbo, Giuseppe, Montes, Margarida, Foschi, Francesco Giuseppe, Vivaldi, Caterina, Lonardi, Sara, Sho, Takuya, Niizeki, Takashi, Nishida, Naoshi, Steup, Christoph, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Hiraoka, Atsushi, Tada, Fujimasa, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Imai, Michitaka, Kosaka, Hisashi, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, Persano, Mara, Foti, Silvia, Piscaglia, Fabio, Scartozzi, Mario, Cascinu, Stefano, and Casadei-Gardini, Andrea

Published
2024
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8. 3D Map Reconstruction of an Orchard using an Angle-Aware Covering Control Strategy

Author

Mammarella, Martina, Donati, Cesare, Shimizu, Takumi, Suenaga, Masaya, Comba, Lorenzo, Biglia, Alessandro, Uto, Kuniaki, Hatanaka, Takeshi, Gay, Paolo, and Dabbene, Fabrizio

Subjects
Electrical Engineering and Systems Science - Systems and Control, Computer Science - Robotics
Abstract

In the last years, unmanned aerial vehicles are becoming a reality in the context of precision agriculture, mainly for monitoring, patrolling and remote sensing tasks, but also for 3D map reconstruction. In this paper, we present an innovative approach where a fleet of unmanned aerial vehicles is exploited to perform remote sensing tasks over an apple orchard for reconstructing a 3D map of the field, formulating the covering control problem to combine the position of a monitoring target and the viewing angle. Moreover, the objective function of the controller is defined by an importance index, which has been computed from a multi-spectral map of the field, obtained by a preliminary flight, using a semantic interpretation scheme based on a convolutional neural network. This objective function is then updated according to the history of the past coverage states, thus allowing the drones to take situation-adaptive actions. The effectiveness of the proposed covering control strategy has been validated through simulations on a Robot Operating System., Comment: 6 pages, 6 figures

Published
2022

9. Efficacy and safety of atezolizumab plus bevacizumab treatment for unresectable hepatocellular carcinoma patients with esophageal–gastric varices

Author

Tada, Fujimasa, Hiraoka, Atsushi, Tada, Toshifumi, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Naganuma, Atsushi, Kosaka, Hisashi, Matono, Tomomitsu, Kuroda, Hidekatsu, Yata, Yutaka, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Yokohama, Keisuke, Nishikawa, Hiroki, Imai, Michitaka, Koizumi, Yohei, Nakamura, Shinichiro, Iijima, Hiroko, Kaibori, Masaki, Hiasa, Yoichi, and Kumada, Takashi

Published
2023
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10. Automatic Generation of Ice Hockey Defensive Motion via Coverage Control and Control Barrier Functions

Author

Tanpipat, Kornvik, Hatanaka, Takeshi, and Hiroura, Masatoshi

Subjects
Electrical Engineering and Systems Science - Systems and Control
Abstract

A successful defensive strategy in ice hockey games is often designed empirically by an experienced professional. The majority of previous work on automating the strategy focuses on analyzing spatial data to decide the most optimal formation and action but cannot generalize the system to real games with real-time capabilities. We propose a novel control logic for generating real-time ice hockey defensive motion based on a control barrier function (CBF) and coverage control to extend our antecessors' logic that succeeds in duplicating ideal formations for specific scenes. To this end, we first present an ellipsoidal CBF to overcome the drawbacks of the existing line-based CBF of our antecessors. We also tune and add a novel density function to reflect real specifications more precisely than the previous work. The control logic is then demonstrated through simulations with offensive motion in real games. It is confirmed that the present logic generates valid defensive movements without specification to these specific scenes. We further exemplify that the logic generates proper motion under ice hockey's man-to-man and zone defense strategies and their intermediate strategies by tuning the logic. This would contribute to reducing the efforts of the practitioners to educate ice hockey players.

Published
2021

11. Passivity-based Analysis and Design for Population Dynamics with Conformity Biases

Author

Yamashita, Shunya, Irifune, Kodai, Hatanaka, Takeshi, Wasa, Yasuaki, Hirata, Kenji, and Uchida, Kenko

Subjects
Electrical Engineering and Systems Science - Systems and Control
Abstract

This paper addresses mechanisms for boundedly rational decision makers in discrete choice problem. First, we introduce two mathematical models of population dynamics with conformity biases. We next analyze the models in terms of delta-passivity, and show that the conformity biases work to break passivity of decision makers. Based on the passivity perspective, we propose mechanisms so as to induce decision makers to a desired population state. Furthermore, we analyze a convergence property of designed mechanisms, and present parameter conditions to guarantee stable inducements.

Published
2021

12. Survival outcomes from atezolizumab plus bevacizumab versus Lenvatinib in Child Pugh B unresectable hepatocellular carcinoma patients

Author

Rimini, Margherita, Persano, Mara, Tada, Toshifumi, Suda, Goki, Shimose, Shigeo, Kudo, Masatoshi, Cheon, Jaekyung, Finkelmeier, Fabian, Lim, Ho Yeong, Presa, José, Salani, Francesca, Lonardi, Sara, Piscaglia, Fabio, Kumada, Takashi, Sakamoto, Naoya, Iwamoto, Hideki, Aoki, Tomoko, Chon, Hong Jae, Himmelsbach, Vera, Schirripa, Marta, Montes, Margarida, Vivaldi, Caterina, Soldà, Caterina, Hiraoka, Atsushi, Sho, Takuya, Niizeki, Takashi, Nishida, Naoshi, Steup, Christoph, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Tada, Fujimasa, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Kosaka, Hisashi, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, Burgio, Valentina, Scartozzi, Mario, Cascinu, Stefano, and Casadei-Gardini, Andrea

Published
2023
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13. Clinical outcomes with atezolizumab plus bevacizumab or lenvatinib in patients with hepatocellular carcinoma: a multicenter real-world study

Author

Persano, Mara, Rimini, Margherita, Tada, Toshifumi, Suda, Goki, Shimose, Shigeo, Kudo, Masatoshi, Cheon, Jaekyung, Finkelmeier, Fabian, Lim, Ho Yeong, Rimassa, Lorenza, Presa, José, Masi, Gianluca, Yoo, Changhoon, Lonardi, Sara, Tovoli, Francesco, Kumada, Takashi, Sakamoto, Naoya, Iwamoto, Hideki, Aoki, Tomoko, Chon, Hong Jae, Himmelsbach, Vera, Pressiani, Tiziana, Kawaguchi, Takumi, Montes, Margarida, Vivaldi, Caterina, Soldà, Caterina, Piscaglia, Fabio, Hiraoka, Atsushi, Sho, Takuya, Niizeki, Takashi, Nishida, Naoshi, Steup, Christoph, Iavarone, Massimo, Di Costanzo, Giovanni, Marra, Fabio, Scartozzi, Mario, Tamburini, Emiliano, Cabibbo, Giuseppe, Foschi, Francesco Giuseppe, Silletta, Marianna, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Tada, Fujimasa, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Kosaka, Hisashi, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, Cammarota, Antonella, Burgio, Valentina, Cascinu, Stefano, and Casadei-Gardini, Andrea

Published
2023
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15. Real-World Data for Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma: How Does Adherence to the IMbrave150 Trial Inclusion Criteria Impact Prognosis?

Author

Rimini, Margherita, Persano, Mara, Tada, Toshifumi, Suda, Goki, Shimose, Shigeo, Kudo, Masatoshi, Cheon, Jaekyung, Finkelmeier, Fabian, Lim, Ho Yeong, Presa, José, Masi, Gianluca, Yoo, Changhoon, Lonardi, Sara, Piscaglia, Fabio, Kumada, Takashi, Sakamoto, Naoya, Iwamoto, Hideki, Aoki, Tomoko, Chon, Hong Jae, Himmelsbach, Vera, Pressiani, Tiziana, Montes, Margarida, Vivaldi, Caterina, Soldà, Caterina, Hiraoka, Atsushi, Sho, Takuya, Niizeki, Takashi, Nishida, Naoshi, Steup, Christoph, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Tada, Fujimasa, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Kosaka, Hisashi, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, Burgio, Valentina, Rimassa, Lorenza, Scartozzi, Mario, Cascinu, Stefano, and Casadei-Gardini, Andrea

Published
2023
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16. Smooth Dynamics for Distributed Constrained Optimization with Heterogeneous Delays

Author

Li, Mengmou, Yamashita, Shunya, Hatanaka, Takeshi, and Chesi, Graziano

Subjects
Mathematics - Optimization and Control
Abstract

This work investigates the distributed constrained optimization problem under inter-agent communication delays from the perspective of passivity. First, we propose a continuous-time algorithm for distributed constrained optimization with general convex objective functions. The asymptotic stability under general convexity is guaranteed by the phase lead compensation. The inequality constraints are handled by adopting a projection-free generalized Lagrangian, whose primal-dual gradient dynamics preserves passivity and smoothness, enabling the application of the LaSalle's invariance principle in the presence of delays. Then, we incorporate the scattering transformation into the proposed algorithm to enhance the robustness against unknown and heterogeneous communication delays. Finally, a numerical example of a matching problem is provided to illustrate the results., Comment: 6 pages, 3 figures

Published
2020
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18. Effectiveness and safety of atezolizumab-bevacizumab in patients with unresectable hepatocellular carcinoma: a systematic review and meta-analysis

Author

Kulkarni, Anand V., Tevethia, Harshvardhan, Kumar, Karan, Premkumar, Madhumita, Muttaiah, Mark D., Hiraoka, Atsushi, Hatanaka, Takeshi, Tada, Toshifumi, Kumada, Takashi, Kakizaki, Satoru, Vogel, Arndt, Finn, Richard S., Rao, Padaki Nagaraja, Pillai, Anjana, Reddy, Duvvur Nageshwar, and Singal, Amit G.

Published
2023
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19. Development and validation of a modified albumin–bilirubin grade and α-fetoprotein score (mALF score) for hepatocellular carcinoma patients receiving atezolizumab and bevacizumab

Author

Hatanaka, Takeshi, Kakizaki, Satoru, Hiraoka, Atsushi, Tada, Toshifumi, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Shimada, Noritomo, Kawata, Kazuhito, Kosaka, Hisashi, Tanaka, Takaaki, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, and Kumada, Takashi

Published
2023
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20. Sequential therapies after atezolizumab plus bevacizumab or lenvatinib first-line treatments in hepatocellular carcinoma patients

Author

Persano, Mara, Rimini, Margherita, Tada, Toshifumi, Suda, Goki, Shimose, Shigeo, Kudo, Masatoshi, Cheon, Jaekyung, Finkelmeier, Fabian, Lim, Ho Yeong, Presa, José, Masi, Gianluca, Yoo, Changhoon, Lonardi, Sara, Tovoli, Francesco, Kumada, Takashi, Sakamoto, Naoya, Iwamoto, Hideki, Aoki, Tomoko, Chon, Hong Jae, Himmelsbach, Vera, Niizeki, Takashi, Montes, Margarida, Vivaldi, Caterina, Soldà, Caterina, Stefanini, Bernardo, Hiraoka, Atsushi, Sho, Takuya, Nishida, Naoshi, Steup, Christoph, Iavarone, Massimo, Di Costanzo, Giovanni, Marra, Fabio, Tamburini, Emiliano, Cabibbo, Giuseppe, Foschi, Francesco Giuseppe, Silletta, Marianna, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Tada, Fujimasa, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Kosaka, Hisashi, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, Campani, Claudia, Amadeo, Elisabeth, Rossari, Federico, Burgio, Valentina, Cascinu, Stefano, Scartozzi, Mario, and Casadei-Gardini, Andrea

Published
2023
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21. Instant MPC for linear systems and dissipativity-based stability analysis

Author

Yoshida, Keisuke, Inoue, Masaki, and Hatanaka, Takeshi

Subjects
Electrical Engineering and Systems Science - Systems and Control, Mathematics - Optimization and Control
Abstract

This letter is devoted to the concept of ``instant'' model predictive control (iMPC) for linear systems. An optimization problem is formulated to express the finite-time constrained optimal regulation control, like conventional MPC. Then, iMPC determines the control action based on the optimization process rather than the optimizer, unlike MPC. The iMPC concept is realized by a continuous-time dynamic algorithm of solving the optimization; the primal-dual gradient algorithm is directly implemented as a dynamic controller. On the basis of the dissipativity evaluation of the algorithm, the stability of the control system is analyzed. Finally, a numerical experiment is performed in order to demonstrate that iMPC emulates MPC and to show its less computational burden.

Published
2019
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22. Prognostic impact of C-reactive protein and alpha-fetoprotein in immunotherapy score in hepatocellular carcinoma patients treated with atezolizumab plus bevacizumab: a multicenter retrospective study

Author

Hatanaka, Takeshi, Kakizaki, Satoru, Hiraoka, Atsushi, Tada, Toshifumi, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Shimada, Noritomo, Kawata, Kazuhito, Kosaka, Hisashi, Tanaka, Takaaki, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Joko, Kouji, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, and Kumada, Takashi

Published
2022
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23. Correction to: Development and validation of a modified albumin–bilirubin grade and α-fetoprotein score (mALF score) for hepatocellular carcinoma patients receiving atezolizumab and bevacizumab

Author

Hatanaka, Takeshi, Kakizaki, Satoru, Hiraoka, Atsushi, Tada, Toshifumi, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Shimada, Noritomo, Kawata, Kazuhito, Kosaka, Hisashi, Tanaka, Takaaki, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, and Kumada, Takashi

Published
2023
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24. Atezolizumab plus bevacizumab versus lenvatinib for unresectable hepatocellular carcinoma: a large real-life worldwide population

Author

Casadei-Gardini, Andrea, Rimini, Margherita, Tada, Toshifumi, Suda, Goki, Shimose, Shigeo, Kudo, Masatoshi, Cheon, Jaekyung, Finkelmeier, Fabian, Lim, Ho Yeong, Rimassa, Lorenza, Presa, José, Masi, Gianluca, Yoo, Changhoon, Lonardi, Sara, Tovoli, Francesco, Kumada, Takashi, Sakamoto, Naoya, Iwamoto, Hideki, Aoki, Tomoko, Chon, Hong Jae, Himmelsbach, Vera, Pressiani, Tiziana, Montes, Margarida, Vivaldi, Caterina, Soldà, Caterina, Piscaglia, Fabio, Hiraoka, Atsushi, Sho, Takuya, Niizeki, Takashi, Nishida, Naoshi, Steup, Christoph, Iavarone, Massimo, Di Costanzo, Giovanni, Marra, Fabio, Scartozzi, Mario, Tamburini, Emiliano, Cabibbo, Giuseppe, Foschi, Francesco Giuseppe, Silletta, Marianna, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Tada, Fujimasa, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Kosaka, Hisashi, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, Burgio, Valentina, Persano, Mara, Della Corte, Angelo, Ratti, Francesca, De Cobelli, Francesco, Aldrighetti, Luca, Cascinu, Stefano, and Cucchetti, Alessandro

Published
2023
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29. Chronological change in serum albumin as a prognostic factor in patients with hepatocellular carcinoma treated with lenvatinib: proposal of albumin simplified grading based on the modified albumin–bilirubin score (ALBS grade)

Author

Kariyama, Kazuya, Hiraoka, Atsushi, Kumada, Takashi, Yasuda, Satoshi, Toyoda, Hidenori, Tsuji, Kunihiko, Hatanaka, Takeshi, Kakizaki, Satoru, Naganuma, Atsushi, Tada, Toshifumi, Takaguchi, Koichi, Itobayashi, Ei, Ishikawa, Toru, Shimada, Noritomo, Tsutsui, Akemi, Nagano, Takuya, Imai, Michitaka, Nakamura, Shinichiro, Wakuta, Akiko, Miyake, Nozomi, Shiota, Shohei, and Nouso, Kazuhiro

Published
2022
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31. Passivity-Based Generalization of Primal-Dual Dynamics for Non-Strictly Convex Cost Functions

Author

Yamashita, Shunya, Hatanaka, Takeshi, Yamauchi, Junya, and Fujita, Masayuki

Subjects
Computer Science - Systems and Control
Abstract

In this paper, we revisit primal-dual dynamics for convex optimization and present a generalization of the dynamics based on the concept of passivity. It is then proved that supplying a stable zero to one of the integrators in the dynamics allows one to eliminate the assumption of strict convexity on the cost function based on the passivity paradigm together with the invariance principle for Caratheodory systems. We then show that the present algorithm is also a generalization of existing augmented Lagrangian-based primal-dual dynamics, and discuss the benefit of the present generalization in terms of noise reduction and convergence speed.

Published
2018

35. C-reactive protein to albumin ratio predicts survival in patients with unresectable hepatocellular carcinoma treated with lenvatinib

Author

Tada, Toshifumi, Kumada, Takashi, Hiraoka, Atsushi, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Tanaka, Takaaki, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Naganuma, Atsushi, Aoki, Tomoko, Koizumi, Yohei, Nakamura, Shinichiro, Joko, Kouji, Hiasa, Yoichi, and Kudo, Masatoshi

Published
2022
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37. A Passivity-Based Distributed Reference Governor for Constrained Robotic Networks

Author

Nguyen, Tam, Hatanaka, Takeshi, Doi, Mamoru, Garone, Emanuele, and Fujita, Masayuki

Subjects
Computer Science - Multiagent Systems, Computer Science - Distributed, Parallel, and Cluster Computing, Computer Science - Robotics, Computer Science - Systems and Control
Abstract

This paper focuses on a passivity-based distributed reference governor (RG) applied to a pre-stabilized mobile robotic network. The novelty of this paper lies in the method used to solve the RG problem, where a passivity-based distributed optimization scheme is proposed. In particular, the gradient descent method minimizes the global objective function while the dual ascent method maximizes the Hamiltonian. To make the agents converge to the agreed optimal solution, a proportional-integral consensus estimator is used. This paper proves the convergence of the state estimates of the RG to the optimal solution through passivity arguments, considering the physical system static. Then, the effectiveness of the scheme considering the dynamics of the physical system is demonstrated through simulations and experiments., Comment: 8 pages, International Federation of Automatic Conference 2017, 8 figures

Published
2017

38. An Integrated Design of Optimization and Physical Dynamics for Energy Efficient Buildings: A Passivity Approach

Author

Hatanaka, Takeshi, Zhang, Xuan, Shi, Wenbo, Zhu, Minghui, and Li, Na

Subjects
Computer Science - Systems and Control
Abstract

In this paper, we address energy management for heating, ventilation, and air-conditioning (HVAC) systems in buildings, and present a novel combined optimization and control approach. We first formulate a thermal dynamics and an associated optimization problem. An optimization dynamics is then designed based on a standard primal-dual algorithm, and its strict passivity is proved. We then design a local controller and prove that the physical dynamics with the controller is ensured to be passivity-short. Based on these passivity results, we interconnect the optimization and physical dynamics, and prove convergence of the room temperatures to the optimal ones defined for unmeasurable disturbances. Finally, we demonstrate the present algorithms through simulation., Comment: 8 pages, 7 figures, to be submitted to IEEE CCTA

Published
2017

39. Stochastic optimal investment strategy for net‐zero energy houses.

Author

Li, Mengmou, Tanaka, Taichi, Carnerero, A. Daniel, Wasa, Yasuaki, Hirata, Kenji, Fujisaki, Yasumasa, Ushifusa, Yoshiaki, and Hatanaka, Takeshi

Abstract

In this research, Net‐Zero Energy Houses (ZEHs) is investigated that harness regionally produced electricity from photovoltaic (PV) panels and fuel cells, integrating them into a local power system in pursuit of achieving carbon neutrality. This article examines the impact of electricity sharing among users who are working towards attaining ZEH status through the integration of PV panels and battery storage devices. Two potential scenarios are proposed: the first assumes that all users individually invest in storage devices, hence minimizing their costs on a local level without energy sharing; the second envisions cost minimization through the collective use of a shared storage device, managed by a central manager. These two scenarios are formulated as a stochastic convex optimization and a cooperative game, respectively. To tackle the stochastic challenges posed by multiple random variables, the Monte Carlo sample average approximation (SAA) is applied to obtain solvable deterministic convex problems. Last, to demonstrate the practical applicability of these models, the proposed scenarios are implemented in the Jono neighborhood in Kitakyushu, Japan. [ABSTRACT FROM AUTHOR]

Published
2024
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40. Predictive factors and survival outcome of conversion therapy for unresectable hepatocellular carcinoma patients receiving atezolizumab and bevacizumab: Comparative analysis of conversion, partial response and complete response patients.

Author

Hatanaka, Takeshi, Kakizaki, Satoru, Hiraoka, Atsushi, Tada, Toshifumi, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Toyoda, Hidenori, Ogawa, Chikara, Nishikawa, Hiroki, Nishimura, Takashi, Kawata, Kazuhito, and Kosaka, Hisashi

Subjects
*CONVERSION therapy, *NEUTROPHIL lymphocyte ratio, *OVERALL survival, *HEPATOCELLULAR carcinoma, *SURVIVAL rate, *BEVACIZUMAB
Abstract

Summary: Aim: This study aims to investigate the predictive factors for conversion therapy in patients with unresectable hepatocellular carcinoma (uHCC) and to evaluate the prognosis of conversion cases by comparing them with partial response (PR) and complete response (CR) cases. Methods: In this retrospective multicentre study, we included a total of 946 uHCC patients treated with atezolizumab and bevacizumab (Atez/Bev) from September 2020 to September 2023. Results: Out of the patients, 43 (4.5%) received conversion therapy following Atez/Bev treatment. The overall response rate was 65.1% and 23.7% in the conversion and non‐conversion group, respectively, with a statistical significance (p < 0.001). Multivariate analyses identified that BCLC stage B or an earlier stage (p = 0.045), absence of macrovascular invasion and extrahepatic spread (p = 0.045), and a low value of neutrophil to lymphocyte ratio (p = 0.04) were significantly favourable predictive factors associated with conversion therapy. The conversion group showed significantly better survival compared to the non‐conversion group (p < 0.001). In the landmark analysis at 6, 12 and 18 months, the conversion group exhibited better survival compared to PR patients in the non‐conversion group (p = 0.04, 0.01 and 0.03, respectively) and there were no significant differences in the overall survival (OS) between the conversion group and patients who achieved a CR (p = 0.7, 1.0 and 0.3, respectively). Conclusions: Patients with low tumour burden and low value of NLR were more likely to undergo conversion therapy. The OS of patients undergoing conversion therapy showed better survival compared to those achieving PR and was comparable to those with CR patients. Conversion therapy could be considered if feasible. [ABSTRACT FROM AUTHOR]

Published
2024
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41. Alpha-fetoprotein and des-gamma-carboxy prothrombin can predict the objective response of patients with hepatocellular carcinoma receiving durvalumab plus tremelimumab therapy.

Author

Saeki, Issei, Shimose, Shigeo, Tomonari, Tetsu, Ito, Takanori, Tani, Joji, Takeuchi, Yasuto, Yoshioka, Naoki, Naito, Takehito, Takeuchi, Mamiko, Kakizaki, Satoru, Hatanaka, Takeshi, Sasaki, Kyo, Yasunaka, Tetsuya, Sakata, Masahiro, Iwamoto, Hideki, Itano, Satoshi, Shirono, Tomotake, Tanabe, Norikazu, Yamamoto, Takafumi, and Kanayama, Yuki

Subjects
TUMOR markers, ODDS ratio, PROGRESSION-free survival, HEPATOCELLULAR carcinoma, PROTHROMBIN, ALPHA fetoproteins
Abstract

Durvalumab plus tremelimumab (Durva/Treme) combined immunotherapy is the first-line therapy recommended for unresectable hepatocellular carcinoma (HCC). Since sequential therapy is more effective in improving prognosis, tumor markers have been used as predictive biomarkers for response to systemic therapy. This study aimed to investigate the predictive ability of objective response (OR) by tumor markers for Durva/Treme therapy against HCC. In this multicenter study, 110 patients with HCC who received Durva/Treme therapy were retrospectively enrolled. The OR rate was 15.5%. To aid early decision-making regarding OR, we evaluated the predictors contributing to OR in two steps: before (first step) and 4 weeks after (second step) treatment induction. Changes in tumor markers (alpha-fetoprotein [AFP] and des-gamma-carboxy prothrombin [DCP]) from baseline to 4 weeks after treatment (ΔAFP/ΔDCP) were included as the input factors. In the first step, multivariable analysis identified only the baseline AFP level (odds ratio 3.497, p = 0.029) as a predictor of OR. Patients with AFP ≥ 400 ng/mL had a significantly higher OR rate than those with < 400 ng/mL (28.2 vs. 8.5%, p = 0.011), and there was no significant difference in progression-free survival (PFS) between the two groups. When AFP/DCP response was defined as a ≥10% reduction from baseline, multivariable analysis showed that AFP response (odds ratio 6.023, p = 0.042) and DCP response (odds ratio 11.657, p = 0.006) were both independent predictors of OR in the second step. The PFS of patients with AFP or DCP response was significantly longer than that of patients without AFP or DCP response. The study demonstrated that the use of AFP and DCP can predict the OR of patients with HCC receiving Durva/Treme therapy. [ABSTRACT FROM AUTHOR]

Published
2024
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48. Disease etiology impact on outcomes of hepatocellular carcinoma patients treated with atezolizumab plus bevacizumab: a real-world, multicenter study

Author

Rossari, Federico, primary, Tada, Toshifumi, additional, Suda, Goki, additional, Shimose, Shigeo, additional, Kudo, Masatoshi, additional, Yoo, Changhoon, additional, Cheon, Jaekyung, additional, Finkelmeier, Fabian, additional, Lim, Ho Yeong, additional, Presa, José, additional, Masi, Gianluca, additional, Bergamo, Francesca, additional, Amadeo, Elisabeth, additional, Vitiello, Francesco, additional, Kumada, Takashi, additional, Sakamoto, Naoya, additional, Iwamoto, Hideki, additional, Aoki, Tomoko, additional, Chon, Hong Jae, additional, Himmelsbach, Vera, additional, Iavarone, Massimo, additional, Cabibbo, Giuseppe, additional, Montes, Margarida, additional, Foschi, Francesco Giuseppe, additional, Vivaldi, Caterina, additional, Soldà, Caterina, additional, Sho, Takuya, additional, Niizeki, Takashi, additional, Nishida, Naoshi, additional, Steup, Christoph, additional, Hirooka, Masashi, additional, Kariyama, Kazuya, additional, Tani, Joji, additional, Atsukawa, Masanori, additional, Takaguchi, Koichi, additional, Itobayashi, Ei, additional, Fukunishi, Shinya, additional, Tsuji, Kunihiko, additional, Ishikawa, Toru, additional, Tajiri, Kazuto, additional, Ochi, Hironori, additional, Yasuda, Satoshi, additional, Toyoda, Hidenori, additional, Ogawa, Chikara, additional, Nishimura, Takashi, additional, Hatanaka, Takeshi, additional, Kakizaki, Satoru, additional, Shimada, Noritomo, additional, Kawata, Kazuhito, additional, Hiraoka, Atsushi, additional, Tada, Fujimasa, additional, Ohama, Hideko, additional, Nouso, Kazuhiro, additional, Morishita, Asahiro, additional, Tsutsui, Akemi, additional, Nagano, Takuya, additional, Itokawa, Norio, additional, Okubo, Tomomi, additional, Imai, Michitaka, additional, Kosaka, Hisashi, additional, Naganuma, Atsushi, additional, Koizumi, Yohei, additional, Nakamura, Shinichiro, additional, Kaibori, Masaaki, additional, Iijima, Hiroko, additional, Hiasa, Yoichi, additional, Persano, Mara, additional, Foti, Silvia, additional, Camera, Silvia, additional, Stefanini, Bernardo, additional, Scartozzi, Mario, additional, Cascinu, Stefano, additional, Casadei-Gardini, Andrea, additional, and Rimini, Margherita, additional

Published
2024
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49. Treatment options for solitary hepatocellular carcinoma ≤5 cm: surgery vs. ablation: a multicenter retrospective study

Author

Kariyama, Kazuya, primary, Nouso, Kazuhiro, additional, Hiraoka, Atsushi, additional, Toyoda, Hidenori, additional, Tada, Toshifumi, additional, Tsuji, Kunihiko, additional, Ishikawa, Toru, additional, Hatanaka, Takeshi, additional, Itobayashi, Ei, additional, Takaguchi, Koichi, additional, Tsutsui, Akemi, additional, Naganuma, Atsushi, additional, Yasuda, Satoshi, additional, Kakizaki, Satoru, additional, Wakuta, Akiko, additional, Shiota, Shohei, additional, Kudo, Masatoshi, additional, and Kumada, Takashi, additional

Published
2024
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