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864 results on '"Hatakeyama, H."'

1. Improvement of critical current density in Fe-sheathed MgB2 tapes by ZrSi2, ZrB2 and WSi2 doping

Author

Ma, Yanwei, Kumakura, H., Matsumoto, A., Hatakeyama, H., and Togano, K.

Subjects
Condensed Matter - Superconductivity
Abstract

Fe-sheathed MgB2 tapes were prepared through the in situ powder-in-tube technique by 5 at.% ZrSi2, ZrB2 and WSi2 doping, respectively. The doping effect of these compounds on the microstructure and superconducting properties of MgB2 tapes has been investigated by using x-ray diffraction, scanning electron microscope, transport measurements and DC susceptibility measurements. Compared to the undoped samples, Jc for all the doped samples were much improved; the best result in terms of Jc was achieved for ZrSi2 doping, by up to a factor of 3.4 at 4.2 K in magnetic fields up to 12 T. Moreover, these dopants did not significantly decrease the transition temperature. The Jc-B curves of WSi2-doped tapes show better performance in higher magnetic fields in comparison to undoped tapes, suggesting that pinning centers effective in a high-field region were possibly introduced., Comment: to be published soon

Published
2003
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2. Application of apolipoprotein E-modified liposomal nanoparticles as a carrier for delivering DNA and nucleic acid in the brain

Author

Tamaru M, Akita H, Nakatani T, Kajimoto K, Sato Y, Hatakeyama H, and Harashima H

Subjects
Medicine (General), R5-920
Abstract

Mina Tamaru,* Hidetaka Akita,* Taichi Nakatani, Kazuaki Kajimoto, Yusuke Sato, Hiroto Hatakeyama, Hideyoshi Harashima Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan *These authors contributed equally to this work Abstract: An innovative drug delivery technology is urgently needed to satisfy unmet medical needs in treating various brain disorders. As a fundamental carrier for plasmid DNA or nucleic acids, we developed a liposomal nanoparticle (multifunctional envelope-type nano device [MEND]) containing a proton-ionizable amino lipid (YSK-MEND). Here we report on the impact of apolipoprotein E (ApoE) modification on the function of YSK-MEND in terms of targeting brain cells. The cellular uptake and function of YSK-MEND encapsulating short interference RNA or plasmid DNA were significantly improved as a result of ApoE modification in mouse neuron-derived cell lines (Neuro-2a and CAD). Intracerebroventricular administration of ApoE-modified YSK-MEND (ApoE/YSK-MEND) encapsulating plasmid DNA also resulted in higher transgene expression in comparison with YSK-MEND that was not modified with ApoE. Moreover, observation of fluorescence-labeled ApoE/YSK-MEND and expression of mCherry (fluorescence protein) derived from plasmid DNA indicated that this carrier might be useful for delivering and conferring transgene expression in neural stem cells and/or neural progenitor cells. Thus, this system may be a useful tool for the treatment of neurodegenerative disease. Keywords: brain, DNA, oligonucleotide, delivery, nanoparticles

Published
2014

11. Thermal Analysis

Author

Hatakeyama, H., Timell, T. E., editor, Lin, Stephen Y., editor, and Dence, Carlton W., editor

Published
1992
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19. Highly reliable high-speed 1.1- [mu]m-range VCSELs with InGaAs/GaAsP-MQWs

Author

Hatakeyama, H., Anan, T., Akagawa, T., Fukatsu, K., Suzuki, N., Tokutome, K., and Tsuji, M.

Subjects
Gallium arsenide -- Electric properties, Gallium arsenide -- Optical properties, Gallium arsenide -- Thermal properties, Indium -- Electric properties, Indium -- Optical properties, Indium -- Thermal properties, Semiconductor lasers -- Thermal properties, Semiconductor lasers -- Electric properties, Failure mode and effects analysis, Business, Computers, Electronics, Electronics and electrical industries
Published
2010

33. The superconducting properties of MgB2/(stainless steel) tapes fabricated by the PIT process

Author

Matsumoto, A., Hatakeyama, H., Kitaguchi, H., Togano, K., and Kumakura, H.

Subjects
Adhesive tape -- Research, Superconductivity -- Observations, Magnesium compounds -- Research, Business, Electronics, Electronics and electrical industries
Abstract

Reporting the effects of area reduction of the tape and annealing conditions of MgB2/(stainless steel) tapes is presented. However, excess cold-rolling of the wires and tapes depressed the J(sub c) values because of the introduction of cracks in the MgB2 cores.

Published
2003

43. Hydrogen-oxygen-vacancy complexes in Czochralski-grown silicon crystal

Author

Hatakeyama, H. and Suezawa, M.

Subjects
Silicon crystals -- Research, Crystals -- Electric properties, Semiconductor doping -- Research, Physics
Abstract

A study was conducted on the generation process and on the characteristics of shallow donors generated through the annealing of an electron irradiated, hydrogen-doped Czochralski-grown silicon crystal. The three types of shallow donors produced were destroyed through annealing at 300-650-degrees C. The first of the three shallow donors was found to be a hydrogen aggregate and a complex of the vacancy-oxygen pair.

Published
1997

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