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1. Appropriateness and clinical outcomes of short sustained low-efficiency dialysis: A national experience

Author

Rahhal Alaa, Najim Mostafa, Mahfouz Ahmed, Habib Mhd Baraa, Hassen Sara Seife, Al-Shekh Isra’a, Ahmed Ashraf Omer, Toba Haneen, Abbarh Shahem, El Hassan Mawahib, Al Yafei Sumaya, Badr Amr, and Mahmoud Khaled Mohamed

Subjects
sustained low-efficiency dialysis, acute kidney injury, mortality, dialysis, Medicine
Abstract

Sustained low-efficiency dialysis (SLED) is usually performed over 6–12 h among hemodynamically unstable patients. Conduction of 4-h SLED may spare time and manpower during hospitalization. Therefore, we conducted a retrospective observational study to explore the appropriateness and clinical outcomes of 4-h SLED among critically ill patients admitted to our center from 1/06/2016 to 1/06/2020. Renal parameters including blood urea nitrogen, serum creatinine, sodium, phosphorus, potassium, and bicarbonate were determined on the day of dialysis before SLED and within 24 h after SLED, and clinical outcomes including, acute kidney injury (AKI) recovery, in-hospital mortality, 30-day mortality, 180-day mortality, and re-admission with AKI, were evaluated. Of the 304 patients included, 69.4% were male. The majority of patients were from the Middle East (65.8%), followed by 28.6% from Asia. Four-hour SLED resulted in a significant improvement in the renal parameters. Recovery from AKI was observed in 25.4%, in-hospital mortality rate was 48.7%, while the 30- and 180-day mortality outcomes were 3.2 and 9.6%, respectively, and re-admission with AKI was observed in 16.9%. Our findings suggest that 4-h SLED significantly improved renal parameters and was associated with favorable clinical outcomes in terms of survival and AKI recovery, suggesting possible utilization of SLED shorter than 6 h in the acute settings to preserve time and manpower for procedures.

Published
2023
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4. Reviewers

Author

Abdolghafoorian, Hamed, Ahmed, Bilawal, Amlani, Shehzad, Angouw, Karina, Apriliani, Adinda K., Aygin, Deren, Badhrinarayanan, Shreya, Baker, Christopher B., Balasoglu, Emalina, Bangero, Joener B., Barba, Carlos E., Beveridge, Tyler S., Bhatti, Usman, Blackburn, Kaitlyn Marie, Bodie, Brandon, Borges, Gonçalo, Brisson, Michael, Brooke, Dewey, Cahilog, Zhen, Carney, Rhonda, Cela, Bekim A., Charboneau, Alex J., Chen, Y.S., Cicani, Laura, Clark, Ryan, Cochran, Sam, Daniels, Natasha, Davies, Taylor, Dilaver, Nafi Mehmet, Dionisie, Repetchi, DuBois, Darcelle, Duenk, Larry L., Dufka, Faustine, Duralde, Erin, Ennes, Alexander Panayotou, Erb, Gregory M., Erdem, Muhammed Said, Fambiatos, Adam, Ferrando, Lisa, Fortin, Francis, Fourie, Helene, Franklin, Jameelah, Ganbat, Dariimaa, Valdez Garcia, Jose Angel, Zúñiga García, José Manuel, Figueroa Garcia, Martha Luisa, Garth, Lauren, Ghaly, Andrew R., Gol-Chambers, Alexandra, Gomes, Joseph, González, Patricia Téllez, Greco, Natalie, Hadjiandreou, Mr. Michalis, Hagar, Emily, Haire, Randolph D., Hamilton, Guy P., Hassen, Sara Seife, Hawks, Stephanie, Highton, Georgina, Hinchey, Sherri A., Hinds, Stephanie Anne, Hines, Adriane, Honeycutt, P. Barrett, Hricz, Craig, Huang, Warren, Hubeishy, Moudi, Ingram, Cameron M., Inouye, Aaron, Jaket, Courtney, Jefferies, Tolbert Dewayne, Jones, Benjamen, Jones, Hayden R., Kaminskaite, Viktorija, Klee, Alan, Krinock, Matthew, Krzywicki, Matthew, Law, Gemma Therese, Lawes, Caitlin M., Lorié, Natalia Soriano, Lowe, Melodie M., Lyon, Zachary, Kamil M., Macauley, Precious, Mahajan, Ankita, Malligan, Hugh J., Marcano, Yobanny Kafruni, Martin, Livingston, Martins, Maria Eduarda P.F., McClure, Amber, Mittal, Ramona, Monge, Eunice, Moran, Sean, Motosko, Catherine, Naidu, Nandita Natasha, Napaul, Gemma, Nayar, Nishchey, Newman, Ory S., Nitsch, Ann Margareth Wagner, Njoku, Eberechukwu G., Obaña, Caryl Joy C., Ogunseyila, Abimbola, Olea, Alain Garcia, Ong, Philip, Otniel, Boingeanu, Pacik, Deborah, Parfitt, Hollie, Paschal, Erika, Pearson, Emma, Phillips, D. Alexander, Pires-Ménard, Alexandra, Rainge-Campbell, Kristian, Ramsay, Joshua G., Randolph, Charles, Rassa, Nazanin, Richmond, Craig Stuart, Rogahn, Megan, Rowe, Aurielle E., Saberi-Movahed, Seena, Sabir, Sarah, Sanchez, Julienne Rowelie A., Santos, Andrea Lizeth Tarazona, Sarlo, Danielle N., Sarwal, Dhruv, Savelkoel, Jelmer, Shane, Matthew R., Shing, Leung, Ka, Shively, Jordan, Sleiman, Naama H., Smeaton, Jessica Zarathena, Smith, Valerie, Strange, Jehu, Stretton, Brandon, Sutton, Louisa, Switzer, Benjamin, Szablewski, Zachary, Tchaconas, Alexis, Thambirajah, Stella, Tompson, Jeffrey D., Tran, Tuyet Hong, Uhm, Tae Kyu, VanHam, Raymond, Varughese, Blessy, Verheyden, Matthew, Vinycomb, Tobias, Viqueira, Marta Costoya, Wang, Gloria Z., Weng, Ow Kok, Wike, Christopher, Wilson, Brent, Wisbeck, Alex, Woodard, Jennifer, Yang, Loo Li, Zaidi, Mohammad, Zhang, Chen, and Zovath, Andrew J.

Published
2017
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5. Cholesterol Granuloma: An Underrecognized Cause of Benign Lung Granuloma.

Author

Hassen SS, Ali GA, Ahmed AO, and Goravey W

Abstract

A cholesterol granuloma is a benign lesion that can occur in various organs, mimicking other pathologies. We present the case of a 35-year-old man presenting with asymptomatic lung and pleural lesions which were suspected to be pulmonary tuberculosis but found to be cholesterol granuloma on biopsy. Cholesterol granulomas are a rare mimic of common lung pathology and should be considered in the differential diagnosis if the initial investigations are not informative., Learning Points: Pulmonary cholesterol granuloma is a benign lesion that radiologically mimics many sinister pathologies.The pathogenesis of pulmonary cholesterol granuloma remains obscure and extensive work-up is usually needed to rule out malignancy and infectious aetiology., Competing Interests: Conflicts of Interests: The authors declare there are no competing interests., (© EFIM 2022.)

Published
2022
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