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11. Determination of Virulence Properties of Leukemia Viruses

Author

Haseltine, W. A., Lenz, J., Crowther, R., Heimpel, H., editor, Huhn, D., editor, Mueller-Eckhardt, C., editor, Ruhenstroth-Bauer, G., editor, Neth, Rolf, editor, Gallo, Robert C., editor, Greaves, Melvyn F., editor, Moore, Malcolm A. S., editor, and Winkler, Kurt, editor

Published
1983
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12. Comparative Analysis of RNA Tumor Virus Genomes

Author

Haseltine, W. A., Pedersen, F. S., Sahagan, B. G., Rosenberg, Z. F., Kozlov, J., Heimpel, H., editor, Huhn, D., editor, Ruhenstroth-Bauer, G., editor, Neth, Rolf, editor, Gallo, Robert C., editor, Hofschneider, Peter-Hans, editor, and Mannweiler, Klaus, editor

Published
1979
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21. Unsung hero Robert C. Gallo

Author

Abbadessa, G., Accolla, R., Aiuti, F., Albini, A., Aldovini, A., Alfano, M., Antonelli, G., Bartholomew, C., Bentwich, Z., Bertazzoni, U., Berzofsky, J., Biberfeld, P., Boeri, E., Buonaguro, L., Buonaguro, F., Bukrinsky, M., Burny, A., Caruso, A., Cassol, S., Chandra, P., Ceccherini-Nelli, L., Chieco-Bianchi, L., Clerici, M., Colombini-Hatch, S., Morghen, C., De Maria, A., De Rossi, A., Dierich, M., Della-Favera, R., Dolei, A., Douek, D., Erfle, V., Felber, B., Fiorentini, S., Franchini, G., Gershoni, J., Gotch, F., Green, P., Greene, W., Hall, W., Haseltine, W., Jacobson, S., Kallings, L., Kalyanaraman, V., Katinger, H., Khalili, K., Klein, G., Klein, E., Klotman, M., Klotman, P., Kotler, M., Kurth, R., Lafeuillade, A., La Placa, M., Lewis, J., Lillo, F., Lisziewicz, J., Lomonico, A., Lopalco, L., Lori, F., Lusso, P., Macchi, B., Malim, M., Margolis, L., Markham, P., Mcclure, M., Miller, N., Mingari, M., Moretta, L., Noonan, D., O'Brien, S., Okamoto, T., Pal, R., Palese, P., Panet, A., Pantaleo, G., Pavlakis, G., Pistello, M., Plotkin, S., Poli, G., Pomerantz, R., Radaelli, A., Robert-Guroff, M., Roederer, M., Sarngadharan, M., Schols, D., Secchiero, P., Shearer, G., Siccardi, A., Stevenson, M., Svoboda, J., Tartaglia, J., Torelli, G., Tornesello, M., Tschachler, E., Vaccarezza, Mauro, Vallbracht, A., Van Lunzen, J., Varnier, O., Abbadessa, G., Accolla, R., Aiuti, F., Albini, A., Aldovini, A., Alfano, M., Antonelli, G., Bartholomew, C., Bentwich, Z., Bertazzoni, U., Berzofsky, J., Biberfeld, P., Boeri, E., Buonaguro, L., Buonaguro, F., Bukrinsky, M., Burny, A., Caruso, A., Cassol, S., Chandra, P., Ceccherini-Nelli, L., Chieco-Bianchi, L., Clerici, M., Colombini-Hatch, S., Morghen, C., De Maria, A., De Rossi, A., Dierich, M., Della-Favera, R., Dolei, A., Douek, D., Erfle, V., Felber, B., Fiorentini, S., Franchini, G., Gershoni, J., Gotch, F., Green, P., Greene, W., Hall, W., Haseltine, W., Jacobson, S., Kallings, L., Kalyanaraman, V., Katinger, H., Khalili, K., Klein, G., Klein, E., Klotman, M., Klotman, P., Kotler, M., Kurth, R., Lafeuillade, A., La Placa, M., Lewis, J., Lillo, F., Lisziewicz, J., Lomonico, A., Lopalco, L., Lori, F., Lusso, P., Macchi, B., Malim, M., Margolis, L., Markham, P., Mcclure, M., Miller, N., Mingari, M., Moretta, L., Noonan, D., O'Brien, S., Okamoto, T., Pal, R., Palese, P., Panet, A., Pantaleo, G., Pavlakis, G., Pistello, M., Plotkin, S., Poli, G., Pomerantz, R., Radaelli, A., Robert-Guroff, M., Roederer, M., Sarngadharan, M., Schols, D., Secchiero, P., Shearer, G., Siccardi, A., Stevenson, M., Svoboda, J., Tartaglia, J., Torelli, G., Tornesello, M., Tschachler, E., Vaccarezza, Mauro, Vallbracht, A., Van Lunzen, J., and Varnier, O.

Published
2009

22. Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody

Author

Marasco, W A, Haseltine, W A, and Chen, S Y

Subjects
Mice, Antibody Formation, CD4 Antigens, Alcohol Dehydrogenase, HIV-1, Animals, Antibodies, Monoclonal, HIV Envelope Protein gp120, Research Article
Abstract

A single-chain antibody, derived from a human monoclonal antibody that recognizes the CD4 binding region of the human immunodeficiency virus type 1 (HIV-1) envelope protein, has been designed for intracellular expression in eukaryotic cells. The single-chain antibody is composed of an immunoglobulin heavy-chain leader sequence and heavy- and light-chain variable regions that are joined by an interchain linker. The antibody is stably expressed and retained in the endoplasmic reticulum and is not toxic to the cells. The antibody binds to the envelope protein within the cell and inhibits processing of the envelope precursor and syncytia formation. The infectivity of the HIV-1 particles produced by cells that express the single-chain antibody is substantially reduced. These studies illustrate the feasibility of designing antibodies that bind and inactivate molecules intracellularly. Antibodies that act on target molecules within cells should provide a useful tool for research as well as for control of infectious and other diseases.

Published
1993

23. Unsung Hero Robert C. Gallo

Author

Abbadessa, G., primary, Accolla, R., additional, Aiuti, F., additional, Albini, A., additional, Aldovini, A., additional, Alfano, M., additional, Antonelli, G., additional, Bartholomew, C., additional, Bentwich, Z., additional, Bertazzoni, U., additional, Berzofsky, J. A., additional, Biberfeld, P., additional, Boeri, E., additional, Buonaguro, L., additional, Buonaguro, F. M., additional, Bukrinsky, M., additional, Burny, A., additional, Caruso, A., additional, Cassol, S., additional, Chandra, P., additional, Ceccherini-Nelli, L., additional, Chieco-Bianchi, L., additional, Clerici, M., additional, Colombini-Hatch, S., additional, de Giuli Morghen, C., additional, de Maria, A., additional, de Rossi, A., additional, Dierich, M., additional, Della-Favera, R., additional, Dolei, A., additional, Douek, D., additional, Erfle, V., additional, Felber, B., additional, Fiorentini, S., additional, Franchini, G., additional, Gershoni, J. M., additional, Gotch, F., additional, Green, P., additional, Greene, W. C., additional, Hall, W., additional, Haseltine, W., additional, Jacobson, S., additional, Kallings, L. O., additional, Kalyanaraman, V. S., additional, Katinger, H., additional, Khalili, K., additional, Klein, G., additional, Klein, E., additional, Klotman, M., additional, Klotman, P., additional, Kotler, M., additional, Kurth, R., additional, Lafeuillade, A., additional, La Placa, M., additional, Lewis, J., additional, Lillo, F., additional, Lisziewicz, J., additional, Lomonico, A., additional, Lopalco, L., additional, Lori, F., additional, Lusso, P., additional, Macchi, B., additional, Malim, M., additional, Margolis, L., additional, Markham, P. D., additional, Mcclure, M., additional, Miller, N., additional, Mingari, M. C., additional, Moretta, L., additional, Noonan, D., additional, O'Brien, S., additional, Okamoto, T., additional, Pal, R., additional, Palese, P., additional, Panet, A., additional, Pantaleo, G., additional, Pavlakis, G., additional, Pistello, M., additional, Plotkin, S., additional, Poli, G., additional, Pomerantz, R., additional, Radaelli, A., additional, Robertguroff, M., additional, Roederer, M., additional, Sarngadharan, M. G., additional, Schols, D., additional, Secchiero, P., additional, Shearer, G., additional, Siccardi, A., additional, Stevenson, M., additional, Svoboda, J., additional, Tartaglia, J., additional, Torelli, G., additional, Tornesello, M. L., additional, Tschachler, E., additional, Vaccarezza, M., additional, Vallbracht, A., additional, van Lunzen, J., additional, Varnier, O., additional, Vicenzi, E., additional, von Melchner, H., additional, Witz, I., additional, Zagury, D., additional, Zagury, J.-F., additional, Zauli, G., additional, and Zipeto, D., additional

Published
2009
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27. Constitutive expression of HIV-1 tat protein in human Jurkat T cells using a BK virus vector

Author

Antonella Caputo, Sodroski, J. G., and Haseltine, W. A.

Subjects
T-Lymphocytes, Genetic Vectors, Gene Expression, Transfection, NO, Cell Line, Cell growth, Virology, Immunology and Allergy, Humans, Pharmacology (medical), BKV, Stable cell lines, HIV-1 tat, Infectious Diseases, BK Virus, DNA, Viral, Gene Products, tat, HIV-1, Trans-Activators, RNA, Viral, tat Gene Products, Human Immunodeficiency Virus, Polyomavirus, Cell Division, Plasmids
Abstract

The production and characterization of Jurkat cell lines that constitutively express functional human immune deficiency virus type 1 (HIV-1) tat protein, using a BK virus plasmid expression vector and HIV-1 tat cDNA, is described. An increased growth rate of these Jurkat-tat cell lines as compared with control cell lines was observed.

Published
1990

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