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Reduction and manipulation using percutaneously fixated Schanz screws and unreamed intramedullary nailing facilitates fracture reduction, promotes early weight bearing, and decreases complications such as nonunion, malalignment, in failure. [ABSTRACT FROM AUTHOR]

This simple, cost-effective technique for creating contrast bone cement with or without antibiotics by the addition of aqueous methylene blue to acrylic bone cement in revision or primary total joint arthroplasty, allows easy visualization for removal of cement from the surgical field. [ABSTRACT FROM AUTHOR]

A computer-assisted technique using computed tomography and three-dimensional imaging for the localization and excision of osteoid osteoma allows minimal bone resection, shortened hospital stay, and prompt weight bearing. [ABSTRACT FROM AUTHOR]

Introduction: Dual mobility acetabular systems for total hip arthroplasty (THA) have been shown to have decreased dislocation rates and reduced revision rates, but there is controversy over the potential release of sufficient levels of metal ions into the blood to cause adverse local tissue reactions. However, there is a lack of long-term studies analyzing these levels of cobalt and chromium. Therefore, the purpose of this study was to investigate the levels these metal ions at a minimum 5-year follow-up after dual mobility implantation. Specifically, we analyzed: 1. overall blood and urine cobalt levels; 2. overall blood and urine chromium levels; 3. cobalt levels stratified by length of follow-up and various implant-related metrics (i.e., offset, cup size, stem, and neck angle); as well as 4. chromium levels stratified by length of follow-up and these various implant-related metrics., Methods: A total of 41 patients who underwent THA with modular dual mobility acetabular systems between January 1, 2011, and December 31, 2016, were identified and followed for a mean time of 6 years (range: 5 to 10 years). All patients had well-functioning hips (Harris Hip Scores greater than 90 points (range: 90 to 100 points) and had no evidence of impending radiographic failure or progressive radiolucencies. Cobalt and chromium serum and plasma, blood, as well as urine levels were obtained at final followup. Additional parameters analyzed included: head material and size, stem offset, cup size, as well as stem-neck angle., Results: Concentrations of cobalt were low as the mean blood and urine levels for all patients were 0.6 ± 0.5 μg/L (normal < 1.8 μg/L) and 0.8 ± 0.8 μg/L (normal < 2.8 μg/L), respectively. Only one patient had a minimally elevated blood cobalt level by 0.1 μg/L. These levels were not substantially different when subgroup analyses were performed for ceramic and cobalt-chrome heads. The mean chromium levels in blood and urine were also found to be low for all patients as values were 0.8 ± 0.2 μg/L (normal: < 1.2 μg/L) and 1.2 ± 0.5 ng/milliliter (normal: < 2 ng/L), respectively. Similarly, only one patient had a very slightly elevated blood chromium level of 1.3 μg/L. Additionally, analyses of ceramic or cobalt-chrome heads separately did not demonstrate differences in blood or urine levels. Blood cobalt or chromium concentrations had minimal changes with longer lengths of follow-ups, and with different stem offsets, cup sizes, stems, or neck angles., Conclusion: Dual mobility acetabular systems when combined with the two stems studied produced low levels of blood as well as urine cobalt and chromium levels at a minimum follow-up of 5 years (mean: 6 years; range: 5 to 10 years). These results remained below the threshold of normal and clinically insignificant regardless of length of follow-up, head material, or various implant measurements. To the best of our knowledge, this is the first study to demonstrate low levels of metal ions at longer than 4-year follow-up. These data may be of importance to surgeons deciding on the appropriate implants to use for their high-risk patients.

Introduction: While dual mobility systems in total hip replacements have demonstrated reduced dislocation and revision occurrences, concerns persist about the potential elevation of metal ions in the bloodstream, leading to negative tissue reactions. Notably, there's a scarcity of research spanning over five years post-surgery that examines cobalt and chromium levels after such implants. This study aimed to delve into these metal ion concentrations after a five-year period, building on previous metal-ion findings. We focused on: (1) cobalt concentrations in blood and urine; (2) chromium concentrations in blood and urine; (3) cobalt variations based on follow-up duration and specific implant metrics (e.g., offset, cup dimension, stem, and neck inclination); and (4) chromium variations based on the same parameters., Materials and Methods: We tracked 57 individuals who received THA using modular dual mobility systems from January 1, 2011, to December 31, 2016, for an average span of six years (ranging from five to 10 years). At the final check-up, we measured cobalt and chromium levels in serum, plasma, blood, and urine. We also evaluated parameters like head composition and dimension, stem offset, cup dimension, and stem-neck inclination., Results: Cobalt concentrations remained minimal, with average blood and urine values being 0.8+0.6mcg/L (standard <1.8mcg/L) and 1.2+1.0mcg/L (standard <2.8mcg/L), respectively. Two individuals exhibited a slight increase in blood cobalt concentration by 0.1 and 0.2mcg/L. Chromium averages in blood and urine were also minimal, with readings of 0.9+0.2mcg/L (standard <1.2mcg/L) and 1.3 + 0.5mcg/L (standard <2mcg/L), respectively. One individual had a marginally increased blood chromium concentration of 1.3mcg/L. Evaluations considering ceramic or cobalt-chrome heads, up to a decade of follow up, or varying implant metrics showed negligible variations in metal ion concentrations., Conclusion: The findings reveal that over a minimum of five years (average = six years; span, five to 10 years), cobalt and chromium concentrations in patients' systems remained within normal limits and were clinically insignificant, irrespective of the follow-up duration, head material, or implant specifications. This underscores the efficacy of dual mobility systems in ensuring minimal metal ion presence.

Morbidly obese patients undergoing cemented primary total knee arthroplasty (TKA) can pose a challenging problem with implant survivorship due to greater stress at the cement-bone interface. With the advent of additive manufacturing (three-dimensional printing), highly porous implants are now readily available. The purpose of this study was to review the results of primary TKA in the morbidly obese (body mass index [BMI] ≥ 40) patient using a highly porous cementless tibial baseplate. This is a retrospective study of 167 TKAs in patients with morbid obesity undergoing primary cementless TKA with a minimum 5-year follow-up. A total of 6 patients died and 14 were lost to follow-up, leaving 147 TKAs in 136 patients with a mean follow-up of 66 months (range 60-79 months). The average age was 59 years (range 36-84 years) and average BMI was 45 kg/m 2 (range 39.5-63.9). Clinical results, patient-reported outcome measures, radiographs, and complications were reviewed. There were 9 failures requiring revision, including 3 for aseptic tibial loosening (2.0%), 2 for deep infection (1.4%), 2 for patellar resurfacing (1.4%), 1 for patella instability (0.7%), and 1 for extensor mechanism rupture (0.7%). Knee Society Score (KSS) improved from 48 to 90 at 2- and 5-year follow-up. KSS function score improved from 49 to 68 and 79 at 2- and 5-year follow-up, respectively. Survivorship with aseptic loosening as the endpoint was 98.0% at 5 years. Cementless TKA using a highly porous tibial baseplate in morbidly obese patients demonstrated excellent clinical results with 98% survivorship at 5 years and appears to offer durable long-term biologic fixation as an alternative to mechanical cement fixation in this challenging group of patients., Competing Interests: A.M. declares the following conflicts of interest: Journal of Arthroplasty: Editorial or governing board; Stryker: IP royalties; paid consultant; paid presenter or speaker; research support S.H. declares the following conflicts of interest: Orthopedics: Editorial or governing board SLACK Incorporated: Editorial or governing board; Stryker: IP royalties; Paid consultant; Paid presenter or speaker; Stock or stock Options; Thieme, Inc., Journal of Hip Surgery, Journal of Knee Surgery: Editorial or governing board; Thieme, Inc., Journal of Knee Surgery, Journal of Hip Surgery: Publishing royalties, financial or material support. The rest authors declare no conflict of interest., (Thieme. All rights reserved.)

Optimal wound closure techniques following total knee arthroplasty (TKA) have focused on enhancing healing potential, preventing infection, yielding satisfactory cosmesis, and allowing early ambulation and functionality. An appropriate layered closure and management of the TKA typically involves addressing the (1) deep fascial layer; (2) subdermal layer; (3) intradermal layer, including the subcuticular region; and (4) final application of a specific aseptic dressing, each of which are covered here in detail. This focused critical review of the literature discusses traditional techniques used in all layers of wound closure following TKA while introducing several emerging popular techniques. For example, absorbable barbed skin sutures and occlusive dressings have the potential to reduce operative time, limit the need for early postoperative visits, obviate the need for suture or staple removal, and safely promote patient communication via telemedicine. As novel wound closure techniques continue to emerge and traditional approaches are improved upon, future comparative studies will assist in elucidating the key advantages of various options. In an extremely important field that has tremendous variability, these efforts may enable the reaching of a classically elusive standard of care for these techniques., Competing Interests: None declared., (Thieme. All rights reserved.)

Advanced imaging used in robotic-assisted total knee arthroplasty (TKA), such as computed tomography (CT)-based three-dimensional (3D) planning, may provide an accurate means of implant sizing preoperatively. The purpose of this study was to examine preoperative CT-based implant planning accuracy for robotic-assisted TKA in patients who have (1) varus deformities, (2) valgus deformities, (3) neutral alignment, and (4) retained hardware. A total of 393 patients underwent a robotic-assisted TKA by a single surgeon received preoperative CT scans. The surgeon reviewed the CT-based model preoperatively and recorded the expected size of the components. The final implants used in each case were recorded and compared with the surgeon's preoperative plan. In all groups of patients, the surgeon's CT-based implant plan was within one size of the implant utilized 100% of the time for both the tibiae and femora. Overall, the surgeon was exactly matched in 319 (81%) and 315 (80%) cases for the femoral and tibial components, respectively. For the femoral component, the mean age for patients in whom the original plan was exactly matched was younger than those whose implants were upsized and older than patients those implants were downsized ( p  = 0.024). Other patient demographics and preoperative knee alignment were not associated with predictive accuracy for femoral or tibial components. Our results demonstrate how preoperative CT-based, 3D planning for robotic-assisted TKA is accurate to within one size of the components in every case (100%), and exactly matched in 80%. The results of this study are important because they demonstrate how CT-based preoperative implant planning for TKA is reliable and accurate across all native knee alignments and other patient-specific factors. In addition, they build on a previous study by the same single surgeon, demonstrating that predictive ability can improve over time. This may be important as we move toward more outpatient surgery with less ability for prostheses inventory at ambulatory sites., Competing Interests: M.A.M. reports personal fees from Stryker Corporation, other from Journal of Knee Surgery, outside the submitted work. H.S.S. has nothing to disclose. S.F.H. reports personal fees from Stryker Corp., other from Thieme, Inc., Journal of Hip Surgery, Journal of Knee Surgery, other from Thieme, Inc., outside the submitted work. R.C.M. reports personal fees from Stryker Corporation, outside the submitted work., (Thieme. All rights reserved.)

Introduction: Dual mobility constructs for THA have been a tremendous advancement for hip arthroplasty surgeons, especially in scenarios where instability is a possibility. While some researchers have reported events of malseating with their use, the authors of the current study believe that this may be avoided by ensuring appropriate surgical technique. Therefore, the purpose of this study was to: (1) describe the surgical techniques that we employ to ensure that the liner is adequately seated; and (2) report the rates of malseating, dislocation, and aseptic loosening among our collective cohort of dual mobility THA patients., Materials and Methods: All patients who underwent THA with a dual mobility construct between January 1, 2010 and December 31, 2018 at four institutions were identified. Those who had less than two years of follow up were excluded. Outcomes of interest included radiographic evidence of liner malseating, aseptic loosening, and dislocation. A total of 1,826 patients who underwent THA with a dual mobility construct were identified. Among these patients, 504 had less than two years of follow up and were excluded from our analysis. The remaining 1,322 patients met our criteria including 941 primary THAs (71.2%) and 381 revision THAs (28.8%)., Results: After a minimum follow-up period of two years, there were only two cases of malseated liners (0.15%). Serial follow ups have demonstrated no movement or changes in the position of the liners over time for both patients. In addition, they have been shown to have normal serum metal ion levels and no clinical complaints after 5.3- and 7.1-year follow up. Seven of 1,322 patients (0.53%) experienced a dislocation. Aseptic loosening of the acetabular cup was diagnosed in one patient 3.4 years postoperatively. In three patients, femoral component loosening occurred after a mean follow-up period of 2.3 years, (1.3 to 3.1 years). Among the 941 primary cases, the incidence of liner malseating was 0.21%, as both patients who experienced this complication were in this subgroup. As stated above, these patients have demonstrated normal serum metal ion levels and no clinical or radiographic sequelae as a result of the liner malseating. The dislocation rate among primary cases was 0.21% (2 of 941). Aseptic loosening of the acetabular component occurred in two (0.21%) while one patient (0.1%) was found to have femoral component loosening at final follow up. Of the 381 revision THAs, there were no cases of liner malseating. Five revision THA patients (1.3%) experienced a dislocation over our study period. Two revision THA patients experienced aseptic loosening of the femoral component (0.79%) at final follow up., Conclusions: The results of this paper demonstrate that malseating is not a prevalent issue with dual mobility THA when appropriate surgical techniques are used. It is hoped that that this paper clarifies the techniques for implantation of these implants and that excellent results can be achieved when care is taken to ensure that liners are well-seated intraoperatively.

Competing Interests: None declared.

Because of the early follow-up positive outcomes with cementless fixation, continued evaluations need to be performed to ensure longer-term efficacy. Additionally, although many studies report on the results of femoral and tibial component fixation, few studies report specifically on patellar outcomes. Therefore, the purpose of this study was to report on the: (1) implant survivorship; (2) complications; and (3) radiographic outcomes in a large cohort of patients who received cementless total knee arthroplasties (TKAs), with particular attention to the patellar component. A total of 261 patients who underwent cementless TKA by a single, high-volume academic surgeon were studied. Patients had a mean age of 66 years and were distributed between 192 women (74%) and 69 men. All patients received the same cementless tibial, femoral, and patellar components. Mean follow-up period was 4.5 years (range, 4-5 years). Primary outcomes evaluated included all postoperative complications, with particular emphasis on the patellar component. Only one patellar loosened leading to a patellar aseptic loosening rate of 0.3% (1 of 261). The one patellar loosening was the component being dislodged after a manipulation under anesthesia (MUA) at 6 weeks. This was revised to a cemented component and the patient is doing well 4 years later. A second patient experienced a patellar tendon rupture, later surgically repaired. Another patient sustained a patella fracture that was managed nonoperatively. The fracture healed by 1 year and the patient continued to have an otherwise successful outcome, now at 2 years follow-up. No progressive radiolucencies, subsidence, or changes in initial postoperative axial alignment were observed at final follow-up. The results from this study highlight a 98% success rate at mean 4.5 years follow-up in a large cohort of patients with a diverse spread of demographic details. Specific to the patella, only one patient experienced an adverse event, which was managed nonoperatively. Therefore, based on this data, patellar fixation in cementless TKA can be considered a safe technique., Competing Interests: None declared., (Thieme. All rights reserved.)

Background:  Newer generation cementless total knee arthroplasty (TKA) designs have provided stronger osteointegration between the implant and bone. Despite excellent survivorship and outcomes with cemented TKAs, areas of concern within the bone-cement interface remain a concern and necessitate studies on alternative constructs. This study assesses: (1) implant survivorship; (2) clinical outcomes; and (3) complications with radiographic outcomes at a 5-year minimum follow-up of cementless highly porous titanium-coated baseplates in TKAs., Methods:  Part of this study has been reported. We retrospectively reviewed a prospectively collected database at a single high-volume institution between July 1, 2013 and June 30, 2014 for patients who underwent a primary TKA using cementless highly porous titanium-coated baseplate implants. Patients were evaluated clinically at postoperative follow-up visits at a minimum of 5 years. To calculate the survivorship, Kaplan-Meier analysis was performed to determine all-cause, aseptic, and septic implant survivorship at each final follow-up for all patients., Results:  A total of 228 TKAs were performed and followed for a minimum of 5 years (range, 5-6 years). As of the latest follow-up, one case of septic loosening of the patellar button and one case of patellar dislodgment secondary to physical manipulation were recorded and revised. Overall, the cohort displayed implant survivorship of 99.5% at 5-year minimum follow-up. Improvements were seen in both Knee Society pain and function scores and were 37 points (range, 17-60 points) and 28 points (range, 15-47 points), respectively. The mean improvement in flexion was 17.8 (range, -20 to 40 degrees) and mean improvement in extension was -5.5 (range, -30 to 5 degrees)., Discussion:  Cementless TKAs serve as strong alternative choice to cemented TKAs. Although cemented fixation is commonly known as the gold standard, results of this study confirm the findings of previous investigations on the survivorship of cementless TKA implants. Therefore, patients who undergo primary TKA with a cementless tritanium baseplate can expect excellent clinical outcomes at a 5-year minimum follow-up., Competing Interests: S. F.H. reports other from Orthopedics, other from SLACK Incorporated, other from Stryker, other from Journal of Hip Surgery, other from The Journal of Knee Surgery, outside the submitted work. M. A. M. reports other from Stryker, other from Microport, other from DJ Orthopaedics, other from Johnson and Johnson, other from Medical Compression Systems, other from Merz, other from Orthosensor, other from Pacira, other from Sage Products, other from Tissue Gene, other from US Medical Innovations, other from National Institutes of Health (NIAMS and NICHD), other from Ongoing Care Solutions, other from American Journal of Orthopaedics, other from Journal of Arthroplasty, other from The Journal of Knee Surgery, other from Orthopedics, other from Surgical Technology International, other from American Academy of Orthopaedic Surgeons, outside the submitted work., (Thieme. All rights reserved.)

Background: Patients undergoing primary total hip arthroplasty (THA) with prior lumbar spine fusion (LSF) are a high-risk group for instability with reported incidence of dislocation as high as 8.3% using fixed bearing femoral heads. Purpose of this study was to determine risk of post-operative instability in patients undergoing primary THA with a history of prior LSF using dual mobility acetabular cups., Methods: This was a multicenter retrospective study with 93 patients undergoing primary THA using a dual mobility cup with a prior history of instrumented LSF. There were 56 females and 47 males with an average age of 66 years (46-87) and average BMI of 30 with mean follow-up of 2.7 years (range 12-124 months). Surgical approach included posterior (63), direct lateral (15), anterior (11), and direct superior (4). Forty-four percent had one level lumbar fusion, 29% with two levels, and 15% with three or more levels fused. The primary outcome investigated was instability., Results: There were no cases of instability or prosthetic joint infection in this group of patients with prior lumbar spine fusion undergoing primary THA using a dual mobility cup. There was one intra-operative periprosthetic femur fracture and one case of aseptic acetabular cup loosening., Conclusion: Patients undergoing THA with prior LSF are at increased risk for instability due to loss of normal spinopelvic relationship. The use of dual mobility cups in patients with prior LSF undergoing primary THA appears promising with no cases of instability in this high-risk group of patients.

Newer generation cementless total knee arthroplasty (TKA) implants continue to develop with demonstrated clinical success in multiple recent reports. The purpose of this study was to investigate (1) survivorship, (2) complications, and (3) clinical outcomes of a newer generation cementless and highly porous titanium-coated base plate manufactured using three-dimensional (3D) printing technology. We reviewed a single-surgeon, longitudinally maintained database of patients who underwent primary TKA using cementless, highly porous titanium-coated base plate implants from July 1, 2013 to December 31, 2016. A total of 523 patients were identified. Of this cohort, 496 patients had a minimum of 2-year follow-up and were included in our final analysis. Among these patients, 72 had bilateral TKA yielding a total of 568 TKAs. There were 133 men and 363 women who had a mean body mass index of 33 kg/m 2 (range, 20-61 kg/m 2 ). The mean age was 66 years (range, 33-88 years). Average follow-up was 36 months (range, 24-48 months). Indications for TKA included osteoarthritis in 432 patients (87%), rheumatoid arthritis in 40 patients (8%), and knee osteonecrosis in 24 (5%) patients. Implant survivorship was defined as any revision leading to explantation of the base plate for any reason. Kaplan-Meier analysis was performed to determine all-cause implant survivorship at final follow-up for every patient. Complications were assessed using the Knee Society standardized list of TKA complications. Clinical outcomes were determined using the Knee Society pain and function scores. Range-of-motion values were also collected. There were a total of four failures, all were due to aseptic loosening with a survivorship rate of 99% at mean follow-up of 3 years (95% confidence interval = 0.984-0.999). In addition, there were a total of 12 surgical and 10 medical complications. Surgical complications did not affect the base plate or result in any additional implant revisions. A total of nine patients had thromboembolic disease complications; all received medical treatment and recovered adequately. Radiological evaluation did not show any signs of loosening or failures in other patients at final follow-up. Knee Society Scores for pain and function improved from 55 and 56 points preoperatively to 92 and 84 points at 2 years postoperatively. Our results are in concordance with the excellent clinical outcomes and survivorship demonstrated for the newer generation cementless TKA implants. In our experience, 3D printed titanium base plates demonstrated clinical success and excellent survivorship at minimum follow-up of 2 years., Competing Interests: M.A.M.: AAOS: Board or committee member Cymedica: Paid consultant DJ Orthopaedics: Paid consultant; Research support Johnson & Johnson: Paid consultant; Research support Journal of Arthroplasty: Editorial or governing board Journal of Knee Surgery: Editorial or governing board Microport: IP royalties National Institutes of Health (NIAMS & NICHD): Research support Ongoing Care Solutions: Paid consultant; Research support Orthopedics: Editorial or governing board Orthosensor: Paid consultant; Research support Pacira: Paid consultant Peerwell: Stock or stock Options Performance Dynamics Inc.: Paid consultant Sage: Paid consultant Stryker: IP royalties; Paid consultant; Research support Surgical Techniques International: Editorial or governing board TissueGene: Paid consultant; Research support.S.F.H.: Orthopedics: Editorial or governing board SLACK Inc.: Editorial or governing board Stryker: IP royalties; Paid consultant; Paid presenter or speaker; Stock or stock Options Thieme, Inc., Journal of Hip Surgery, Journal of Knee Surgery: Editorial or governing board Thieme, Inc., Journal of Knee Surgery, Journal of Hip Surgery: Publishing royalties, financial or material support.K.L.S.: Fidiapharma: Paid presenter or speaker.J.T.M.: AAOS: Board or committee member American Association of Hip and Knee Surgeons: Board or committee member Corin U.S.A.: IP royalties; Paid consultant DePuy, A Johnson & Johnson Company: IP royalties Invuity: Stock or stock Options Stryker: Paid consultant; Paid presenter or speaker Think Surgical: Stock or stock Options.R.M.M.: Stryker: Paid consultant; Paid presenter or speaker; Research support Zimmer: Research support.V.E.K.: Journal of Arthroplasty: Editorial or governing board Stryker: IP royalties; Paid presenter or speaker Stryker Orthopaedics: Paid consultant Journal of Arthroplasty, Stryker., (Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.)

Total hip and knee arthroplasties may be associated with a significant amount of perioperative blood loss. The severity of blood loss may be great enough to require the use of blood transfusions to treat perioperative anemia. Various methods of blood preservation have been studied. The use of antifibrinolytics and antifibrinolytic-like agents to reduce perioperative bleeding has been researched in orthopaedics and other surgical subspecialties. This review aims to evaluate the current evidence supporting the use of tranexamic acid, aminocaproic acid, fibrin tissue adhesive, and aprotinin in the reduction of perioperative blood loss in total hip and knee arthroplasties., (© 2019 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.)

Introduction: Modular Dual Mobility (MDM) constructs in total hip arthroplasty (THA) offer increased hip stability compared with constrained liners, without compromising hip range of motion. The purpose of this study was to evaluate outcomes of revision THA using MDM., Methods: The study was a multiinstitutional retrospective cohort study of 315 hips that underwent revision THA using MDM between 2011 and 2017. Clinical outcomes and reasons for failure were collected., Results: Three hundred fifteen patients met 1-year minimum follow-up (mean 3.3 years). Nine hips had instability postoperatively (2.9%), and 30 hips required reoperation (9.5%). Seven had recurrent instability (6.5%) which was associated with liner-only exchange (P = .021) and liner outer diameter of ≤ 38 mm (P = .016)., Conclusion: Revision THA with MDM provided a low rate of instability and reoperation in a revision cohort. Recurrent instability following use of MDM in revision THA was associated with retention of the acetabular component and polyethylene outer diameter ≤ 38 mm., Level of Evidence: Therapeutic Level III., (Copyright © 2019 Elsevier Inc. All rights reserved.)

Background: Instability can account for over 20% of all revision total hip arthroplasties (THAs). Although a number of surgical techniques have been developed to limit the number of dislocations, prevention still remains a challenge. More recently, dual mobility (DM) cups have been developed to potentially target this problem. Although this implant design has been shown to have a number of potential advantages in the revision setting, there is limited data in the literature on the use of modular dual mobility (MDM) implants for primary THAs. Therefore, the purpose of this study was to evaluate cup survivorships, patient satisfaction outcomes, and complications of this device used for primary THA., Materials and Methods: A total of 143 consecutive hips (131 patients) who underwent primary THA using DM prostheses by a high-volume academic surgeon were longitudinally followed up for a minimum of five years (mean: 6 years, 11 months; range, 6 years 3 months to 7 years 5 months). There were 77 women (54%) and 66 men (44%) who had a mean age 65 years (range, 34 to 90 years; SD, 11 years), and the mean body mass index (BMI) was 32 kg/m2 (range, 22 to 52; SD, 8 kg/m2). Patient demographics, (gender, BMI), as well as clinical outcomes were analyzed. Kaplan-Meier analysis was performed to determine aseptic, septic, and all-cause cup survivorship. Additionally, clinical outcomes based on Harris Hip Scores (HHS) and other modalities, as well as complications, were tabulated. Institutional review board (IRB) approval was received prior to initiating this study., Results: Septic survivorship was found to be 99.3% (95% CI: 0.98 to 1.0), while all-cause survivorship was 98.6% (95% CI: 0.97 to 1.0). There were a total of two revision surgeries; however, these were not related to the MDM cup. Specifically, one patient had femoral stem loosening, while another patient had a late deep infection treated with a two-stage procedure. At most recent follow up, both patients were progressing well and had HHS scores of 85 and 92 points. The mean total HHS score was 95 points (range, 64 to 100) at most recent follow up. Other complications affecting patient outcomes included two patients who presented with concerns for deep vein thrombi, which were both medically managed, as well as one patient who had a non-fatal pulmonary embolism, which was also medically managed. The final HHS scores for these three patients were 83, 100, and 96 points., Conclusion: DM cups were designed with the intent of reducing hip instability. Most studies on these cups have reported on revision THA, where the problem of instability may be more paramount; however, fewer studies have reported on the use of this cup for primary THA. The findings from this study indicate excellent survivorship and overall clinical and patient satisfaction results using this construct. These five-year results are very encouraging and hopefully will portend excellent further survivorship with longer follow up.

Total number of citations has been considered a proxy for a published study's importance within a given field. However, there are multiple pitfalls to correlating the total number of citations alone with the quality of a study. In this review, the authors aimed to identify the top 100 most-cited studies of hip and knee arthroplasty and then assess study design and quality of reporting. More than half of these studies were level IV evidence, unblinded, not randomized, and not controlled. This underscores the need for higher-quality study design to support practice. [Orthopedics. 2019; 42(2):e151-e161.]., (Copyright 2019, SLACK Incorporated.)

The purpose of this study was to (1) determine the growth rate and the trends of musculoskeletal cellular therapy trials in the National Institutes of Health Clinical Trials Data Bank; (2) analyze the study design and characteristics; and (3) assess which cellular therapies and disease conditions are studied. A systematic review of musculoskeletal clinical trials from 2005 to 2016 using cell-based therapies as the primary intervention was performed through ClinicalTrials.gov. The number of musculoskeletal cell-based clinical trials is increasing, with most being early stage, phase I/II, and using autologous cells harvested mostly from bone marrow to target cartilage-related diseases. Among the 282 clinical trials identified, only 99 (35.1%) were completed; 62 of the 99 (62.6%) did not list any related publications. [Orthopedics. 2019; 42(2):e144-e150.]., (Copyright 2019, SLACK Incorporated.)

Background: Total knee arthroplasty (TKA) in the morbidly obese patients can be challenging with an increased risk of complications. Studies have shown increased aseptic failures with well-aligned cemented TKAs in the obese patient. The purpose of this study is to determine if TKA in the morbidly obese (body mass index [BMI] ≥ 40) using cementless implants would demonstrate improved results and survivorship compared to cemented TKA at a minimum 5-year follow-up., Methods: This is a retrospective study comparing clinical results of cemented vs cementless primary TKA with a posterior stabilized design TKA in morbidly obese (BMI ≥ 40) patients with minimal 5-year follow-up. There were 108 patients in the cementless group with a mean BMI of 45.6. In the cemented cohort, there were 85 cemented TKAs with a mean BMI of 45.0. Demographic, clinical, surgical, and radiographic data along with complications were extracted for all study patients., Results: There were 5 failures requiring revision in the cementless group, including 1 for aseptic tibial loosening (0.9%). In the cemented group, there were 22 failures requiring revision, including 16 implants for aseptic loosening (18.8%; P = .0001). Survivorship with aseptic loosening as the endpoint was 99.1% in the cementless group vs 88.2% in the cemented cohort at 8 years (P = .02)., Conclusion: Morbidly obese patients (BMI ≥ 40) have a higher failure due to aseptic loosening with cemented TKA with decreasing survivorship over time. The use of cementless TKA in morbidly obese patients with the potential of durable long-term biologic fixation and increased survivorship appears to be a promising alternative to mechanical cement fixation., (Copyright © 2018 Elsevier Inc. All rights reserved.)

Knee pain is a highly prevalent condition in the United States with multiple etiologies, with two of the most common sources being osteoarthritis (OA) and patellofemoral pain (PFP). These conditions can lead to reduced physical function and a poor quality of life. Various modalities have been used to decrease the amount of knee pain that individuals' experience; however, they are not always successful and can be expensive. Several studies have reported on specialized footwear for symptomatic alleviation of conditions that affect the knee, this is because it has been theorized that certain footwear can alter the forces placed by muscles on lower-extremity joints, and can potentially alleviate pain by reducing the load placed on the joint. Therefore, the purpose of this study was to review the current literature on the use of various types of footwear used in patients who suffer from knee pain. Specifically, we evaluated: (1) knee OA and (2) PFP and the effect that different footwear has on patients' symptoms. Multiple different types of footwear and orthosis were utilized to treat patients with chronic knee pain. However, the results from reported outcomes by different studies are conflicting, which warrant further studies. Nevertheless, there are enough positive results to view this as a potential major modality to utilize for the treatment of knee OA., Competing Interests: Michael Mont: AAOS, Cymedica, DJ Orthopaedics, Johnson & Johnson, Journal of Arthroplasty, Journal of Knee Surgery, Microport, National Institutes of Health (NIAMS and NICHD), Ongoing Care Solutions, Orthopedics, Orthosensor, Pacira, Peerwell, Performance Dynamics Inc, Sage, Stryker: IP royalties, Surgical Techniques International, TissueGene. Steven Harwin: Orthopedics, SLACK Incorporated, Stryker, Thieme, Inc., Journal of Hip Surgery, Journal of Knee Surgery: Thieme, Inc., Journal of Knee Surgery, Journal of Hip Surgery. Morad Chughtai: DJ Orthopaedics, Sage Products, Stryker. Anil Bhave: Cymedica, DJ Orthopaedics, Guardian Inc, On Going Care, Journal of Society of Indian Physiotherapists., (Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.)

Competing Interests: Disclosure The authors report no conflicts of interest in this work., (Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.)

This review evaluated (1) original and newer cementless implants; (2) outcomes of newer designs; (3) risks and benefits; and (4) newer cementless vs cemented total knee arthroplasties. A search for all reports on cementless total knee arthroplasties published from January 2010 to April 2017 was performed, and 31 studies were included for final analysis. Newer cementless total knee arthroplasty designs have shown excellent survivorship, functional outcomes, and satisfaction rates in both young and elderly populations. Compared with cement fixation, there may be potential benefits with the newer cementless implants. However, these findings need to be further substantiated with additional studies reporting longer-term results. [Orthopedics. 2018; 41(5):263-273.]., (Copyright 2018, SLACK Incorporated.)

As surgical techniques and pharmacology advance, the management of postoperative pain in patients undergoing total knee arthroplasty (TKA) continues to evolve. The current standards of care are composed of multimodal pain management including opioids, nonsteroidal anti-inflammatory drugs and gabapentinoids, peripheral nerve blocks, and periarticular injections. Newer modalities are composed of delayed release local anesthetics and cryoneurolysis. To summarize the current evidence-based treatment modalities and forecast changes in the management of patients having TKAs, we reviewed available data on: (1) oral analgesics; (2) periarticular injections; (3) peripheral nerve blocks; (4) multimodal regimens; and (5) newer modalities in post-TKA pain management. Multimodal analgesic regimens that target numerous pain pathways may provide the best pain management, rehabilitation, patient satisfaction, and reduce opioid use and related side effects. Periarticular injections of delayed-release local anesthetics may further enhance pain management., Competing Interests: Dr. Mont, Dr. Kelly, and Dr. Elmallah are paid consultants for Pacira Pharmaceuticals Inc., (Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.)

Introduction: Arthrofibrosis remains a major complication following total knee arthroplasty (TKA) that negatively impacts patient outcomes and exhausts healthcare resources. The use of neuromuscular electrical stimulation (NMES) has demonstrated the ability to facilitate quadriceps muscle recovery and reduce pain. Therefore, the purpose of this study was to compare TKA patients who received physical therapy (PT) and adjuvant NMES therapy versus physical therapy alone in terms of: 1) rates of manipulation under anesthesia (MUA) to treat arthrofibrosis; and 2) post-therapy range of motion (ROM)., Materials and Methods: This was a retrospective review of TKA patients from multiple institutions who underwent physical therapy versus physical therapy and adjuvant NMES therapy following primary TKA. A total of 206 patients were reviewed in the two cohorts that either received PT alone (n=86) or PT and adjuvant NMES therapy (n=120). Data regarding the requirement of MUA postoperatively for treatment of arthrofibrosis were collected for every patient. Additionally, pre- and post-therapy knee ROM data was also collected. Outcomes in both cohorts were then compared and analyzed., Results: Lower rates of arthrofibrosis requiring MUA were recorded in patients who used NMES therapy and PT when compared to PT alone (7.5% vs. 19.8%; p=0.009). Log regression analysis revealed lower odds of needing MUA in patients who utilized NMES therapy in adjunct with PT (odds ratio [OR]=0.36; 95% CI: 0.115 to 0.875; p=0.023). Patients who received the NMES therapy were shown to have a statistically greater mean improvement in ROM when compared to those patients who did not receive NMES (+2.63, p=0.04). Log regression analysis also demonstrated that post-PT ROM decreased the odds of receiving MUA with a larger ROM (OR=92; 95% CI: 0.824 to 0.9855; p<0.001)., Conclusion: This study demonstrated that the use of NMES during PT may reduce the incidence of arthrofibrosis and improve patient ROM. Prospective, randomized controlled, and larger-scale studies are needed to validate these results. Nevertheless, this novel report demonstrated the positive outcomes for a new application of the NMES therapy.

Background: This study evaluated (1) survivorship, (2) clinical outcomes, (3) complications, and (4) radiographic outcomes of dual mobility (DM) systems when compared to fixed-bearing prostheses in revision total hip arthroplasty (THA)., Methods: A cohort of 85 patients who underwent revision THA using DM implants were compared to a prior matching cohort of 170 patients who received fixed-bearing implants. Mean follow-up time was 4 years in the DM cohort and 10 years in the fixed-bearing cohort. Kaplan-Meier analysis was performed to assess survivorships. Clinical outcomes were evaluated using the Harris Hip Score (HHS). Complications and radiographs were evaluated and reported at the final follow-up., Results: Overall aseptic and all-cause survivorships of the DM cohort were 96.5% and 95.3% compared to 94.7% and 93.5% in fixed-bearing cohort (P = .01 for aseptic and all-cause survivorships). The DM cohort had statistically significant higher survivorship when compared at equivalent follow-up interval in the fixed-bearing cohort. There were 3 aseptic (one due to dislocation) and 1 septic revision in the DM cohort compared to 9 aseptic (6 due to dislocation) and 2 septic revisions in the fixed-bearing cohort. Postoperative HHS scores were 88 and 86 points in the DM and fixed-bearing cohorts. However, the difference in mean improvement in HHS scores from preoperative to postoperative (ΔHHS) was not statistically significant (35 vs 34, P = .533). Except for the aforementioned revisions, there were no progressive radiolucencies or osteolysis on radiographic evaluation in both cohorts., Conclusion: DM articulations demonstrated superior survivorship at equal follow-up intervals when compared to fixed-bearing implants and showed a trend toward lower dislocation rates., (Copyright © 2017 Elsevier Inc. All rights reserved.)

Background: The purpose of this study is to evaluate (1) implant survivorship; (2) patient outcomes; (3) complications; and to (4) perform a radiographic analysis of cementless posteriorly stabilized total knee arthroplasty (TKA) patients at a minimum of 7-year follow-up., Methods: Our original cohort was composed of 114 consecutive cementless posteriorly stabilized total knee arthroplasties (110 patients) performed by a single surgeon between 2008 and 2010. Since our original report, 4 (1 bilateral) patients died and 2 were lost to follow-up. Therefore, there were 104 patients who had 107 knees available for final follow-up. The final cohort included 43 men and 61 women, who had a mean age of 69 years (range 47-87) and were followed from 7 to 9 years (mean 8 years). Patient outcomes and complications were obtained from electronic medical records. Radiographic assessment was done using the Knee Society Radiographic Evaluation System., Results: The all-cause survivorship was 98% (95% confidence interval 1.01-0.96). Since the original report, there has been 1 post-traumatic loosening of the tibial baseplate, and 1 revision for instability. There were no femoral revisions or patella revisions. The mean Knee Society pain score was 93 points (range 80-100) and the function score was 78 points (range 68-95). Excluding revisions, there was no evidence of progressive loosening of any implant components., Conclusion: Based on these 7-year minimum follow-ups, femoral, tibial, and patellar cementless hydroxylapatite-coated beaded implants perform well at up to 9 years postoperatively and offer surgeons and patients a cementless option that may provide long-lasting biological fixation., (Copyright © 2017 Elsevier Inc. All rights reserved.)

The objective of this study was to evaluate implant survivorship, clinical outcomes, postoperative complications, and radiographic outcomes of cementless total knee arthroplasty (TKA) in patients who have rheumatoid arthritis (RA). Patients who underwent a primary cementless posterior-stabilized TKA and who had RA were reviewed. A total of 126 TKAs in 122 patients who had a mean follow-up of 4 years were analyzed. Implant survivorship was calculated. Postoperative clinical and radiographic follow-up was performed at approximately 6 weeks and 3 months and then annually. Changes in range of motion and Knee Society scores were noted. Radiographic evaluation was conducted as part of the follow-up process. Implant survivorship was 99.2%, with 1 aseptic failure. At final follow-up, mean extension and flexion were 2° (range, 0°-10°) and 124° (range, 95°-140°), respectively. Mean Knee Society pain and function scores were 92 points (range, 80-100 points) and 84 points (range, 70-90 points), respectively. There were no surgical complications. No progressive radiolucencies, loosening, or subsidence were noted except from the single aseptic failure reported. This study reports excellent survivorship and clinical and radiographic outcomes of cementless TKAs in RA patients. Although the decision regarding whether to use cemented or cementless TKAs in these patients should be based on surgeon experience and patient characteristics, the recent advances in implant fixation of cementless TKAs indicate no salient contraindications for RA patients. [Orthopedics. 2018; 41(2):103-106.]., (Copyright 2018, SLACK Incorporated.)

Background: Lack of consensus exists on the use of cementless total knee arthroplasty (TKA) in patients with knee osteonecrosis. Therefore, this study was conducted to evaluate (1) implant survivorship; (2) clinical outcomes and complications; and (3) radiographic outcomes of primary cementless TKA in knee osteonecrosis., Methods: This study included 46 patients (49 knees) who had knee osteonecrosis and underwent primary cementless TKA and had a mean follow-up of 44 months (range 36-96). Kaplan-Meier analysis was used to evaluate implant survivorship. Follow-up was performed post-operatively at 6 weeks, 3 months, and annually thereafter. Clinical outcomes including the Knee Society Scores (KSS) for pain and function, changes in range-of-motion, complications, and radiographic outcomes were analyzed., Results: Aseptic implant survivorship was 97.9% (95% confidence interval 1.01-0.93) and all-cause implant survivorship was 95.9% (95% confidence interval 1.01-0.9), with 1 septic and 1 aseptic failures. The mean KSS for pain was 93 points (range 85-100) and the mean KSS for function was 84 points (range 70-90). Additionally, 1 patient had superficial wound necrosis and was treated with local wound care with no further sequela. Otherwise, no evidence of loosening, subsidence, or progressive radiolucencies were noted on radiological evaluation., Conclusion: Excellent implant survivorship, clinical, and radiographic outcomes of primary cementless TKA in the setting of knee osteonecrosis was demonstrated. Although further long-term study is needed to validate survivorship, new generation cementless TKA implants provide promising results in this subset of patients., (Copyright © 2017 Elsevier Inc. All rights reserved.)

Background: Bone loss in patients undergoing revision THA poses a considerable challenge for orthopaedic surgeons. Often, to achieve better fixation in remaining bone, larger diameter acetabular components and reaming superiorly may be necessary. However, this is likely to raise the hip center of rotation, which may lead to altered biomechanics, specifically, insufficiency of the abductor muscles, altered gait, and increased risk of dislocation from impingement. More recently, a newer acetabular shell has been designed to more closely replicate the native hip center of rotation in these circumstances while maintaining adequate fixation., Questions/purposes: The purpose of this study was to compare the radiographic parameters of this newer design with conventional hemispheric cups in revision THA. Specifically, we assessed the differences in (1) vertical center of rotation (COR) displacement and (2) horizontal COR displacement., Methods: Between January 2016 and April 2016, five reconstructive surgeons at five institutions utilized a newer highly porous acetabular shell designed with peripheral screw holes and vertically eccentric COR to allow for restoration of center of hip rotation in revision THA. We included all patients who received this device. During this time, the general indications at these sites for using the new device included Paprosky Stage IIA, IIB, IIC, or IIIA acetabular defects. This yielded 29 patients who were subsequently matched (one to two) by cup size and sex to a cohort who underwent revision THA with conventional hemispheric cups between January 2015 and May 2016. To determine hip COR, radiographic measurements were performed. A circle contiguous to the acetabulum was drawn and the center was determined as the hip COR. All measurements were made from the interteardrop line for both the revised and native hips. A line through the teardrops was used for all horizontal measurements. Center position adjustments were made based on the manufacturer-specified values. Comparisons were performed using chi-square tests for categorical and t-tests for continuous variables. There was no difference in the severity of bone loss before the revision in the groups, as evidenced by Paprosky staging of preoperative radiographs., Results: The mean vertical COR displacement was smaller in patients who had the novel cup (3.5 mm; range, -12 to 15 mm; mean difference, -7.3 mm; 95% confidence interval [CI], -13.2 to -1.5) as compared with those who had the conventional cup (10.5 mm; range, -4 to 50 mm; mean difference, 7.3 mm; 95% CI, -12.5 to -2.2; p = 0.003). There was no difference in mean horizontal displacement between the two groups (-0.06 ± 6.1 versus 1.7 ± 7.1; mean difference, -1.8; p = 0.903)., Conclusions: Although hip COR was improved based on radiographic measurements with the use of this novel acetabular design, and although this may improve hip biomechanics, more studies are required before its widespread adoption for revision cases of this nature can be recommended. Both implant costs and the risks associated with using a new design in practice will have to be justified by studies that evaluate fixation, clinical function and implant survival, and patient-reported outcome scores, all of which were beyond the scope of this preliminary report., Level of Evidence: Level III, therapeutic study.

This multicenter study evaluated survivorship, functional outcomes, complications, and radiographic outcomes for patients who underwent total hip arthroplasty using a newly developed highly porous 3-dimensional titanium implant. Excellent aseptic (99.6%) and all-cause (98%) survivorship and functional outcomes were found at 3-year follow-up. This highly porous acetabular shell holds promise in total hip arthroplasty. [Orthopedics. 2018; 41(1):e154-e157.]., (Copyright 2017, SLACK Incorporated.)

Multiple surgical and nonsurgical treatment options exist for patients with elbow stiffness. Many nonsurgical mobilization bracing options have been implemented to increase elbow range of motion. Three of the main bracing options for these patients are turnbuckle, static progressive stretch, and dynamic bracing. The purpose of this study was to review the current literature on turnbuckle, static progressive stretch, and dynamic bracing to provide information for practitioners and patients regarding which brace is more appropriate to use for elbow stiffness. Specifically, the authors compared the protocol and duration of splint use and changes in range of motion outcomes between static progressive and dynamic brace cohorts. A search of PubMed yielded 8 studies meeting inclusion criteria. Overall, although all 3 bracing options are available for patients, these studies found that, based on the evaluated metrics, the static progressive brace was a markedly superior option for patients with elbow stiffness. The time required to wear the static progressive stretch brace was 13 times less than that for the turnbuckle and 5 times less than that for the dynamic devices. Additionally, the high failure rate (10%) and low success rate (29%) of the dynamic brace, compared with the 63% regaining of functional range of motion in the static progressive stretch group, further highlight the benefits of the static progressive stretch brace. [Orthopedics. 2018; 41(1):e127-e135.]., (Copyright 2017, SLACK Incorporated.)

Competing Interests: Disclosure The authors report no conflicts of interest in this work.

Proper femoral component alignment in the axial plane during total knee arthroplasty (TKA) depends on accurate bone cuts and soft tissue balancing. Two methods that are used to achieve this are "measured resection" and "gap balancing." However, a controversy exists as to which method is more accurate and leads to better outcomes. Therefore, the purpose of this study was to evaluate: (1) implant survivorship, (2) patient outcomes, (3) complications, and (4) radiographic analysis comparing patients who underwent TKA with either gap-balancing or measured resection techniques. A total of 214 consecutive patients (221 knees) underwent primary TKA by a single surgeon between 2011 and 2012. Component alignment was achieved by using measured resection in 116 knees and gap balancing was used in 105 knees. The patients had a mean age of 66 years (range, 44-86 years) and a mean body mass index of 32 kg/m 2 (range, 22-52 kg/m 2 ). Patient range-of-motion (ROM) and Knee Society (KS) function and pain scores, and radiographic assessment, were assessed preoperatively and postoperatively at ∼6 weeks, 3 months, 1 year, and then annually. The mean follow-up time was 3 years. A Kaplan-Meier's analysis was performed to calculate the survivorship. The aseptic survivorship was 98% in both the measured resection and gap-balancing groups. The mean ROM was not significantly different between the measured resection and gap-balancing groups (123 vs. 123 degrees, p  = 0.990). There were no significant differences between the two groups in terms of the KS function scores (86 vs. 85 points, p  = 0.829) or the KS pain scores (93 vs. 92 points, p  = 0.425). Otherwise, the radiographic evaluation at latest follow-up did not demonstrate any evidence of progressive radiolucencies or loosening, of any prosthesis. The results of this study found that at a mean follow-up of 3 years, both the measured resection and gap-balancing techniques achieved excellent survivorship and postoperative outcomes. This demonstrates that both methods can be used to achieve accurate femoral component alignment with similar short-term outcomes., Competing Interests: Conflict of Interest: Michael A. Mont is a consultant for, or has received institutional or research support from the following companies: Sage Products, TissueGene, OnGoing Care Solutions, DJO Global, Microport, Orthosensor, National Institutes of Health, Stryker, Johnson & Johnson, Pacira Pharmaceuticals, Merz, US Medical Innovations. He is on the editorial/governing board of the American Journal of Orthopedics, Journal of Arthroplasty, Journal of Knee Surgery, and Surgical Technology International. He is board or committee member of AAOS. Steven F. Harwin is a consultant for, or has received institutional or research support from the following companies: Orthopedics, SLACK Incorporated, Stryker, Thieme, Inc. He is on the editorial/governing board of the Journal of Hip Surgery and Journal of Knee Surgery., (Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.)

Background: Younger patients undergoing cemented total knee arthroplasty (TKA) may be at risk for lower implant survivorship and higher revision rates due to the historical increased prevalence of aseptic loosening and instability in this cohort. The recent advances of cementless TKAs may mitigate some of these complications. However, there is a paucity of studies reporting on patients who are under 50 years who have undergone a cementless TKA. Therefore, this study evaluated: (I) implant survivorship; (II) functional outcomes and complications; and (III) radiographic outcomes in patients who were less than 50 years of age and underwent cementless TKA., Methods: A total of 29 patients (31 knees) younger than 50 years who underwent primary TKA at a single institution (Mount Sinai Beth Israel, New York, New York, USA) from June 2008 to May 2014 were included. Their mean follow-up was 4 years (range, 2 to 6 years). The cohort included 20 women and 9 men who had a mean age of 45 years (range, 34 to 49 years), and a mean body mass index (BMI) of 33 kg/m 2 (range, 22 to 54 kg/m 2 ). The preoperative knee diagnoses were osteoarthritis (n=24), osteonecrosis (n=5), and rheumatoid arthritis (n=2). A Kaplan-Meier analysis was used to calculate the all cause implant survivorship. Functional outcomes and all complications were recorded for each patient. Additionally, radiographic evaluation using the new Knee Society Radiographic Evaluation and Scoring System was performed., Results: The overall implant survivorship was 100%; there were no failures or revision surgeries performed as of the latest follow-up visit. At the latest follow-up, the mean Knee Society pain score was 92 points (range, 80 to 95 points) and the mean Knee Society function score was 84 points (range, 70 to 90 points). Additionally, the mean knee extension was 1 degree (range, 0 to 5 degrees) and the mean knee flexion was 125 degrees (range, 95 to 140 degrees). Furthermore, at the latest follow-up, on radiographic evaluation, there was no evidence of component loosening, subsidence, radiolucency, gap formation, or reactive changes, and there were no postoperative complications., Conclusions: Cementless fixation of TKAs had excellent survivorship and functional and radiographic outcomes at midterm follow-up in patients younger than 50 years. Although longer follow-up is needed, these cementless TKA implants appear to provide promising results in younger patient populations., Competing Interests: Conflicts of Interest: Dr. Mont is a paid consultant for Stryker and receives research support and IP royalties from Stryker. Dr. Harwin is a paid consultant and paid presenter or speaker for Stryker. He receives IP royalties and holds stock or stock options from Stryker. The other authors have no conflicts of interest to declare.

Healthcare systems are receiving increasing pressures from payers, such as the Centers for Medicare and Medicaid (CMS), to reduce the costs associated with procedures, and with the implementation of the Affordable Care Act, high costs are addressed through pay-for-performance programs. Thus, multiple areas of total knee arthroplasty (TKA) surgery are under scrutiny, including surgical times, material costs, and the costs of associated complications and readmissions. Suture type has been determined to be a factor that may influence closure times, as well as direct material costs. Therefore, the purpose of this review was to compare: (I) the cost of using barbed vs. conventional interrupted sutures; (II) the additional cost of differences in complications, if any; (III) to extrapolate cost savings on a hospital and national level; and (IV) to discuss the role of these findings on hospital savings and the effect on bundled payments. It was found that the main factors affecting differences in overall costs between barbed and standard interrupted suture were material cost and closure time. Many studies have demonstrated greater cost savings with the barbed suture due to shorter operative times, despite the higher material costs. The majority of studies also demonstrated similar complication rates between the suture types, and thus these are unlikely to affect the cost difference. However, to the best of our knowledge, there are no TKA studies in the literature evaluating the effect of suture type and associated complications on lengths of stay and readmission rates. Thus, it is unclear how these cost savings will translate to reimbursements rates and the role that they might play in bundled payments. Several studies in other specialties demonstrate decreased infection rates with the use of barbed sutures, which, if found to be true for TKA can be extrapolated to 3 million dollars of savings in revision TKA costs. Further studies on this topic are needed to define these relationships., Competing Interests: Conflicts of Interest: Dr. Mont is a paid consultant for Ethicon Inc. and receives research support from Ethicon Inc. Dr. Elmallah is a paid consultant for Ethicon Inc. The other authors have no conflicts of interest to declare.

Patient satisfaction assessments, such as the Press Ganey surveys, have been adopted by the Centers for Medicare & Medicaid Services to help determine reimbursements. It is uncertain what facets most affect survey scores among patients who have received total joint arthroplasty (TJA). This study explored which factors guide scores for TJA patients. Specifically, the authors assessed (1) which Press Ganey survey features affected the patients' overall hospital rating and (2) whether survey scores were disparate between patients who did and patient who did not have complications. The authors' institutional Press Ganey database was queried for lower-extremity TJAs that occurred between November 2009 and January 2015. This yielded 1454 patients with a mean age of 63 years (range, 15-92 years; 60% women and 40% men). The database contains information related to American Society of Anesthesiologists scores, Press Ganey question responses, and demographics. Multiple regression analysis was performed to assess the association (beta weight) between Press Ganey domains and overall hospital rating. The weighted mean for each domain was calculated. The authors' analysis revealed that overall hospital rating was significantly influenced by communication with nurses (beta weight=0.434, P<.001), responsiveness of hospital staff (beta weight=0.181, P=.001), communication with doctors (beta weight=0.115, P=.014), and hospital environment (beta weight=0.100, P=.039). No significant differences were found when comparing the Press Ganey scores of patients with and without complications. By recognizing these elements, physicians can direct measures appropriately, which may help avoid financial penalties and possibly increase patient satisfaction after TJA. [Orthopedics. 2017; 40(6):377-380.]., (Copyright 2017, SLACK Incorporated.)

Some surgeons have been hesitant to use cementless fixation for total knee arthroplasty (TKA) in elderly patients due to concerns regarding successful bone biological fixation. Therefore, this study evaluated: (1) implant survivorship, (2) functional outcomes, (3) radiographic outcomes, and (4) complications in patients over 75 years of age who underwent cementless total knee arthroplasty. A total of 134 patients (142 TKAs) older than 75 years at a single institution between June 2008 and June 2014 were retrospectively reviewed. Their mean follow-up was 4 years (range: 2-8 years). The cohort consisted of 91 women and 43 men who had a mean age of 80 years (range: 76 to 88 years). The preoperative diagnoses were osteoarthritis ( n  = 107 patients), rheumatoid arthritis ( n  = 21 patients), and osteonecrosis ( n  = 6 patients). Descriptive statistics were used to calculate the means and ranges and a Kaplan-Meier analysis was performed to determine the aseptic and all cause implant survivorship. Radiographic evaluation was performed using the new Knee Society Radiographic Evaluation and Scoring System. Functional outcomes at the final follow-up as well as all medical and surgical complications were recorded for each patient. The aseptic implant survivorship was 99.3% (95% CI: 7.9-8.1), and the all cause implant survivorship was 98.6% (95% CI: 7.9-8.1). There was one aseptic revision and one septic revision. At the latest follow-up the mean Knee Society pain score was 93 points (range, 80-100 points), and the mean Knee Society function score was 84 points (range, 70-90 points). On radiographic evaluation, there were no progressive radiolucencies, subsidence, and loosening of prostheses at the latest follow-up. The use of cementless TKA demonstrated excellent survivorship, mid-term clinical and functional outcomes, as well as no progressive radiolucencies or subsidence in patients older than 75 years. In addition, there was a low rate of surgical and medical complications. Therefore, cementless TKA may be a good option for patients older than 75 years., Competing Interests: Conflict of Interest: Dr. Mont reports grants and personal fees from DJ Orthopaedics, grants and personal fees from Johnson & Johnson, personal fees from Merz, other from Microport, grants from National Institutes of Health, grants from Ongoing Care Solutions, grants and personal fees from Orthosensor, personal fees from Pacira Pharmaceuticals, personal fees from Sage Products, Inc, grants and personal fees from Stryker, grants and personal fees from TissueGene, personal fees from US Medical Innovations, other from AAOS, other from American Journal of Orthopedics, other from Journal of Arthroplasty, other from Journal of Knee Surgery, other from Orthopedics, other from Surgical Technology International, outside the submitted work.Dr. Harwin is on the editorial/governing board for Journal of Arthroplasty, Orthopedics, Journal of Knee Surgery, Surgical Technology International. He receives publishing royalties and financial/material support from SLACK Incorporated, Thieme Inc, and Journal of Knee Surgery. He receives IP royalties and stock/stock options from Stryker. He is a Paid consultant/presenter/speaker for Stryker and Convatec., (Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.)

Competing Interests: Disclosure The authors report no conflicts of interest in this work.

Competing Interests: Disclosure The authors report no conflicts of interest in this work.

Background: It is estimated that 3%-6% of orthopedic patients, many of whom may undergo lower extremity total joint arthroplasty, are infected with hepatitis C. The purpose of this study was to assess the outcomes of patients with hepatitis C who undergo total hip arthroplasty (THA) in comparison with a matched control cohort in terms of (1) patient-reported outcomes, (2) implant survivorship, and (3) complications., Methods: Fifty-four hips in 49 hepatitis C-infected patients who underwent a primary THA between 2002 and 2011 were reviewed. This included 10 women and 39 men who had a mean age of 57 years and a mean 6.5-year follow-up. These patients were matched to 163 THAs (148 patients) who did not have this disease and underwent a THA during the same period. We compared implant survivorship, complication rates, Harris hip scores, and University of California, Los Angeles, activity scores. Radiographs were evaluated for loosening, fracture, malalignment, and osteolysis., Results: The implant survivorship in the hepatitis C-infected patients and comparison group was 96.2% and 98.7%, respectively. The risk of revision surgery in the hepatitis C cohort was 3-fold higher than the comparison group; however, this difference was not significant (P = .26). The hepatitis C-infected cohort had a higher risk of surgical complications (odds ratio = 6.5; P = .034). There were no differences in postoperative Harris hip scores or University of California, Los Angeles, activity scores between the cohorts., Conclusion: Hepatitis C patients can achieve good implant survivorship and clinical outcomes after THA. However, these patients may be at an increased risk for surgical complications and revision rate., (Copyright © 2017 Elsevier Inc. All rights reserved.)

Competing Interests: Conflict of Interest: Dr. Mont is a consultant for or has received institutional or research support from the following companies: Sage Products, TissueGene, OnGoing Care Solutions, DJO Global, Microport, Orthosensor, National Institutes of Health, Stryker, Johnson & Johnson, Pacira Pharmaceuticals, Merz, US Medical Innovations. He is on the editorial/governing board of the American Journal of Orthopedics, Journal of Arthroplasty, the Journal of Knee Surgery, and Surgical Technology International. He is a board/committee member of AAOS. Dr. Delanois is a paid Consultant and paid presenter/speaker for Corin. He is also a board/committee member for the Maryland Orthopaedic Association. Dr. Harwin is a paid consultant, paid presenter/speaker for, receives royalties from, or holds stock in Stryker and Convatec. He receives publishing royalties and financial or material support from Thieme, Inc, the Journal of Knee Surgery, and SLACK Incorporated. He is on the editorial or governing board for Journal of Arthroplasty, Journal of Knee Surgery, Orthopedics, and Surgical Technology International.

Competing Interests: Disclosure The authors report no conflicts of interest in this work.

Background: Recent healthcare reform has spurred important changes to provider reimbursement. With the implementation of the Value Based Purchasing program, significant weight is placed on patient experience of care. The Press Ganey (PG) survey is currently used by over 10,000 hospitals, as it serves to help optimize patient satisfaction. However, confounding factors, such as clinical depression, are not screened against by PG. Thus, arthroplasty surgeons performing lower extremity total joint arthroplasty (TJA) may have difficulty optimizing patient satisfaction while caring for patients with clinical depression. Therefore, we asked: 1) What Press Ganey elements affect the overall hospital rating in patients who suffer from clinical depression? and 2) Are survey responses different between patients who do and do not have clinical depression?, Materials and Methods: We queried our institutional PG database for patients who underwent a TJA from November 2009 to January 2015. Our search yielded 1,454 patients, of which 204 suffered from depression and 1,250 did not. Multiple regression analysis was performed to determine the influence (b weight) of selected PG survey domains on overall hospital rating. The weighted mean for domain was also calculated., Results: Multiple regression analyses showed that overall hospital ratings were significantly influenced by communication with nurses (b-weight = 0.881, p< 0.001) in post-TJA patients with depression. The remaining domains were not statistically significant. There were no significant differences in individual PG elements for patients who did and did not have depression., Conclusion: Overall patient satisfaction among patients with depression was greatly influenced by communication with nurses. Understanding these challenges may encourage care coordination across disciplines for the management of patients with depression before and after surgery. As a result, this could optimize orthopedic surgery outcomes, but, more importantly, patient health and satisfaction, while reducing costs of care.