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von Willebrand, Vitamin D and platelet diagnostics: The table shows the results for each patient, listed to patient ID according to Table 1, with unit and normal measurement range in brackets depending on the respective laboratory where the analysis was performed. For Vitamin D and functional platelet analysis, normal ranges differ among those depending on the commercial test used. Bold red values show deviation from the normal range. Stroked out values are not available in the specific laboratory of examination (n.a.d. = no applicable disease). (DOCX 111 kb)

Background The vascular type represents a very rare, yet the clinically most fatal entity of Ehlers-Danlos syndrome (EDS). Patients are often admitted due to arterial bleedings and the friable tissue and the altered coagulation contribute to the challenge in treatment strategies. Until now there is little information about clotting characteristics that might influence hemostasis decisively and eventually worsen emergency situations. Results 22 vascular type EDS patients were studied for hemoglobin, platelet volume and count, Quick and activated partial thromboplastin time, fibrinogen, factor XIII, von Willebrand disease, vitamin D and platelet aggregation by modern standard laboratory methods. Results show a high prevalence of over 50 % for platelet aggregation disorders in vascular type EDS patients, especially for collagen and epinephrine induced tests, whereas the plasmatic cascade did not show any alterations. Additionally, more than half of the tested subjects showed low vitamin D serum levels, which might additionally affect vascular wall integrity. Conclusion The presented data underline the importance of detailed laboratory screening methods in vascular type EDS patients in order to allow for targeted application of platelet-interacting substances that might be of decisive benefit in the emergency setting.

Blood count and plasmatic coagulation laboratory results: The table shows the results for each patient, listed to patient ID according to Table 1, with unit and normal measurement range. Bold red values show deviation from the normal range. Stroked out values are not available in the specific laboratory of examination. (DOCX 74 kb)

Mathieu Molitor gehört zu den in Vergessenheit geratenen Künstlern der Zeit um 1900. Bis heute erhalten geblieben - und in aller Welt bekannt - sind die beiden Figurengruppen zu Goethes 'Faust' am Eingang zu Auerbachs Keller in der Leipziger Mädlerpassage. Mit der vorliegenden Arbeit wird versucht, das Gesamtwerk zusammenzutragen, in einem Werkverzeichnis zu erfassen und in einen wissenschaftlichen Kontext einzuordnen.:1. Einleitung / Arbeitsansatz und Quellenlage 2. Leipzig um 1900 3. Biographische Bemerkungen 4. Malerei, Zeichnung, Graphik 5. Gebrauchsgraphik, Buchillustration und Kunsthandwerk 6. Exlibris 7. Plastik 8. Zusammenfassung Tabellarischer Lebenslauf / Ausstellungsverzeichnis / Konkordanzliste Literaturverzeichnis Werkverzeichnis Abbildungen