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Background and Aim: Coat color is a phenotypic trait that is affected by many functional genes. In addition, coat color is an important characteristic of breeds in livestock. This study aimed to determine functional genes for coat color patterns in Sumatran native cattle in Indonesia using a genome-wide association study method. Materials and Methods: A bovine single nucleotide polymorphism (SNP) 50K BeadChip was used for the investigation. A total of 46 Sumatran native cattle of three colors as follows: Brown (36 animals), white (9 animals), and black (1 animal), were used as experimental animals. Results: Results showed that the SNP markers ARS-BFGL-NGS-75486 (p = 2.46×10-7) and BTB-01992588 (p = 1.06×10-5) were selected as two genetic markers for coat color variation in animals under study, which were located at the cytoplasmic FMR1-interacting protein 2 (CYFIP2) gene at BTA7 and small G protein signaling modulator 1(SGSM1) genes at BTA17, respectively. The polymorphic informative content values of both SNP markers were 0.33 (ARS-BFGL-NGS-75486) and 0.13 (BTB-01992588). In this study, a genetic marker for coat color patterns in Sumatran native cattle was obtained based on the haplotypes of both SNP markers. Conclusion: It can be concluded that CYFIP2 and SGSM1 are two coloration genes that affect the phenotype characteristics of Sumatran native cattle.

Latar Belakang: Pembangunan peternakan berkelanjutan menjadi hal utama terhadap faktor pengembangan peternakan. Pengembangan usaha peternakan berkaitan langsung dengan populasi ternak di Indonesia. Populasi ternak harus mampu menjadi faktor keberhasilan pengembangan peternakan. Peternakan harus mampu menghasilkan populasi ternak unggul serta dapat meningkatkan pendapatan. Fakta bahwa populasi ternak berhubungan erat dengan investasi, telah ditunjukkan untuk potensi dan peluang investasi dapat meningkatkan nilai usaha peternakan. Dalam beberapa tahun terakhir, sub sektor peternakan di Indonesia mengalami peningkatan yang signifikan dalam investasi. Seperti yang ditunjukkan oleh data Statistik Peternakan dan Kesehatan Hewan 2023, PDB Peternakan tahun 2022 sebesar Rp178,1 triliun (atas harga konstan) atau meningkat 6,24% dari PDB Peternakan tahun 2021 sebesar Rp298,0 triliun (atas harga berlaku), memberikan kontribusi 16,51% terhadap PDB Sektor Pertanian. Selain itu, hasil realisasi investasi PMDN Peternakan pada tahun 2022 sebesar Rp3,9 triliun atau meningkat 82,74% (terjadi peningkatan dibandingkan dengan tahun sebelumnya). Artinya bahwa besaran nilai PDB dan PMDN dipengaruhi juga oleh besaran nilai kontribusi sub sektor peternakan di Indonesia. Tantangan sub sektor peternakan yaitu mampu mencukupi kebutuhan sumber daya ternak yang lebih besar dan perlu adanya perluasan infrastruktur di bidang peternakan. Ada pengaruh hubungan antara pembangunan peternakan berkelanjutan dengan jumlah populasi ternak. Jika populasi ternak tinggi maka dapat meningkatkan produktifitas peternakan. Reviews: Tulisan ini akan mengulas secara singkat terkait di sub sektor peternakan yaitu Pengaruh Populasi, Jumlah Pemotongan, Hasil Produksi Ternak terhadap Produk Domestik Bruto (PDB), dan Penanaman Modal Dalam Negeri (PMDN)

Fingerprint powder remains one of the most effective techniques for identifying individuals from their latent fingerprints. Visualizing latent fingerprints requires powder with high color contrast and strong adhesive to be easily applied on various substrates. The utilization of silica gel extracted from local materials of Lapindo volcanic mud can be applied for fluorescent fingerprint powder based on methyl orange. The powder was synthesized by the sol-gel method, followed by the impregnation of methyl orange as a dye with varying loads. The powders exhibit an amorphous structure and nanoparticle size with an average particle diameter of 80.93 nm by spherical morphology interconnected to form agglomerations. The powder contains silanol, siloxane, azo, and carboxylate functional groups derived from its precursors. The dusting method proves the performance of fluorescent fingerprint powder on porous and non-porous substrates hereafter observed under white light and UV light. The powder containing 0.05 gs of methyl orange per gram of silica gel is the most effective in revealing fingerprint patterns on non-porous surfaces. It has mesoporous properties with a specific surface area of 7.95 m2g−1 and a pore diameter of 23.14 nm. SiMO retained its full capability after two years of storage, indicating it is a great choice for forensic investigations.

The transformation of Qur'anic exegesis methodology through digital platforms has revolutionized the way the science of tafsir is conveyed and received by the public. The limitations of accessibility and interactivity in traditional methods, which rely on oral and written explanations, have necessitated a new, more engaging, and interactive approach through digital technology. The purpose of this research is to analyze and evaluate the methodology of Qur'anic interpretation used in the tafsir studies on the YouTube channel "Kajian Tafsir Al-Ma'rifah" by Musthafa Umar. This study is descriptive qualitative research utilizing a literature review method. Primary data was collected from the tafsir study videos on the "Kajian Tafsir Al-Ma'rifah" YouTube channel, while secondary data was obtained from textbooks, scholarly articles, and relevant tafsir books. The findings of the research indicate that the use of visual and audio elements in the tafsir videos enhances understanding and information retention among the audience. Additionally, interactive features such as comments, likes, and shares create a dynamic dialogue between the interpreter and the audience, strengthening engagement and participation in the learning process. Digital technology, through platforms like YouTube, not only facilitates access to Qur'anic exegesis but also enriches its delivery methods, making it more inclusive and effective in reaching a global audience. This research contributes to the literature on the transformation of tafsir methodology in the digital era and provides practical recommendations for the development of dakwah through digital platforms.

Community empowerment and household waste processing are two issues that need to be resolved by the government. An independent and educated society is an important pillar to support the development of country. Meanwhile, waste that continues to accumulate without processing has a negative impact on health and the environment. Public education about household waste processing can be a solution to the two problems above. Education was carried out at Junior High School YBPK Surabaya and residents of Dukuh Kupang Surabaya, and other participants who joined in a hibrid meeting with a total of 116 participants. Activities at YBPK Surabaya took place on 25 March and 5 August 2023 and activities at Dukuh Kupang Surabaya took place on 27 May and 26 August 2023. The types of waste processed are organic waste and used cooking oil, which are then converted into eco-enzymes and used cooking oil Activities are divided into 2 stages. there are community education activities and program sustainability monitoring activities. The community education activities includes presentation and workshop were hold in March 2023 at YBPK Surabaya Middle School and May 2023 at Dukuh Kupang Surabaya. The evaluation of sustainability program including individual practice and monitoring of activities was carried out in August 2023 at Dukuh Kupang Surabaya. Methods for implementing activities include presentation, practice accompanied by a mentor, individual practice, and monitoring program sustainability. Based on the analysis of participants' ability, the participant scores before and after the activity was increase. It means that this training succeeded in increasing participants' knowledge and skills in processing waste, especially organic waste and used cooking oil waste. A total of 72 out of 116 participants (62%) had processed household waste either individually or in groups. Activity evaluation data shows that these activities are necessary and on target to create an independent and creative society.

Background and Aim: Runs of homozygosity (ROH) is a biocomputational technique for identifying homozygous regions in the genomics of livestock. This study aimed to determine the ROH in Sumba Ongole (SO) bulls (n = 48) using the BovineSNP50K BeadChip. Materials and Methods: GenomeStudio 2.0 software was used to generate the BovineSNP50K BeadChip output. The ROH and ROH-based inbreeding coefficients (FROH) were determined using the detect RUNS R v4.1.0 package. Using the following filtering criteria, PLINK v1.90 software was used to perform genotype quality control: (1) Individuals and single-nucleotide polymorphism (SNPs) had call rates >0.95; (2) more than 0.05 was the minor allele frequency; (3) the list contained only SNPs linked to autosomes; and (4) SNPs that strongly deviated (p < 1e-6) from Hardy–Weinberg equilibrium were removed. Subsequently, 25,252 autosomal SNP markers were included in the ROH and FROH analyses. Results: In general, the number and length of ROH segments in pool animals were 149.77 ± 16.02 Mb and 486.13 ± 156.11 Mb, respectively. Furthermore, the ROH segments in the animals under study can be discriminated into two classes of 1–4 Mb (83.33%) and 4–8 Mb (16.67%). Subsequently, Bos taurus autosomes (BTA) 1, BTA6, and BTA14 had significant homozygous segments comprising 13 genes. Despite this, the average FROH in pool animals was 0.20 ± 0.06. Conclusion: These findings indicate that a recent inbreeding event in SO cattle occurred many generations ago. Furthermore, the candidate genes identified from the ROH analysis indicate phenotypic attributes associated with environmental adaptation and economic traits.

On June 10, 2020, President Joko Widodo ratified the amendment of Law Number 4 of 2009 to Law Number 3 of 2020 concerning Minerals and Coal, one of the substances that changed the rules of authority in granting licenses from initially located in the local government to the central government. Therefore, this study aims to analyse the issue of authority between the central government and local governments in coal mining management after the issuance of the Minerba Law in 2020. This research uses a qualitative approach using institutional data surveys as a data collection method. The collected data is analysed using descriptive analysis: data reduction, data presentation, and conclusion drawing. The findings in this study explain that in Law Number 3 of 2020 concerning Amendments to Law Number 4 of 2009 concerning Mineral and Coal Mining, the authority of local governments is withdrawn to the central government, starting from Mining Business License (IUP), People's Mining License (IPR) and Special Mining Business License (IUPK), Special Mining Business License (IUPK), Rock Mining License (SIPB), Transfer Permit, Transportation and Sales Permit, Mining Service Business License (IUJP), and Sales IUP. Although all local government authorities are fully withdrawn from mining licensing, local governments can still carry out mining licensing if the central government delegates authority based on statutory provisions. This latest regulation emerged through the idea of the government together with the House of Representatives on the grounds of simplifying licensing by easing requirements to increase investment obtained by the state. However, this change makes it seem as if the government wants to return to the era of centralisation. It is contrary to the spirit of decentralisation and regional autonomy that is being embraced in Indonesia.

The role of mesoporous solid acid aluminosilicate in the oleic acid deoxygenation was elucidated using ZSM-5 and Al-MCM-41 impregnated with Ni. The mesoporous supports were synthesized using a similar initial Si/Al ratio but employing different templates to vary the mesopores. ZSM-5_T produced interparticle mesopores when using TPAOH (tetrapropylammonium hydroxide) as a template. Meanwhile, ZSM-5_S with a well-defined intraparticle mesoporous channel was formed using a silicalite template. Al-MCM-41 synthesized without a template produced one-dimensional highly ordered mesoporous channels. The arrangement of mesoporosity in aluminosilicate determined the mechanistic pathway of oleic acid conversion into hydrocarbon. Oleic acid underwent primary thermal cracking into carboxylic acid before progressing into the subsequent decarbonylation reaction. The diesel hydrocarbon yield was enhanced following the order of Al-MCM-41>ZSM-5_S>ZSM-5_T>blank reaction. Large intraparticle mesoporosity produced long-chain carboxylic acid from catalytic cracking of oleic acid, which was subsequently deoxygenated into long-chain hydrocarbons.

The catalytic conversion of Reutealis trisperma oil was carried out over a Al-MCM-41 based catalyst with different Si/Al ratio with no added hydrogen to examine the possibility of the direct production of hydrocarbons in the ranges of jet fuel. In a semi-batch reactor, RTO was combined with 3 % catalyst and heated to 350 °C for 4h. The blank reaction shows the lowest conversion and liquid yield, with values of 39.65 % and 8.74 %, respectively. In contrast, the highest conversion was achieved using the Al-MCM-41 (30) catalyst, and the conversion decreases as the Si/Al ratio of the Al-MCM-41 catalyst increases. Indeed, the mesoporous structure enabled extensive bio-oil diffusion and adsorption, further increasing catalytic conversion. The Al-MCM-41 (30) shows the great performance in catalytic conversion of RTO to hydrocarbon and aromatic chain hydrocarbon. The Al-MCM-41 (30) catalyst resulted in a composition of 41.26 % paraffin, 6.78 % olefin, 21.77 % arenes, and 11.44 % cycloparaffin. This composition is comparable to JP-8 and Jet-A fuels, satisfying the ASTM D7566 standard for aircraft turbine fuel containing synthetic hydrocarbons. The acid site and pore size on the support material influenced the interaction of bio-oil molecules and catalyst which increasing the rate of reactant/product diffusion and improve the jet-fuel production. The obtained results are promising for the use of non-edible RTO and kaolin-derived catalysts in the production of sustainable alternative jet fuels. This approach offers competitive costs and significant environmental and social benefits.

The purpose of this research is to see how the legislation on forestry licensing regulations before and after the Job Creation Law. This research uses normative juridical conceptual, statutory, and historical types. The study found that the politics of forestry law has a significant impact as it relates to the dominance and stakes between an economy focused on investment interests and sustainable forest area cover during the development process. Previous problems related to forest management were not addressed by the legal regulations related to licensing in the forestry sector of the CK Law. However, the provisions of the CK Law focus on the exploitation of forest resources, which may exacerbate carbon emissions as investment in forest utilization increases. On the one hand, the changes made to the provisions of the Forestry Law in the CK Law are expected to increase investment because they simplify licensing, allow multi-businesses, and allow foreign investment to enter. On the other hand, the changes have a negative impact on natural resource management because they remove commitments to maintain certain forests, confirm and maintain differences in the utilization of forest products between large entrepreneurs and traditional communities, and marginalize communities.

Genome-wide association study (GWAS) was used to detect candidate genes affecting economic traits in livestock. GWAS can detect single nucleotide polymorphisms (SNPs) in all chromosome regions. This study aimed to determine the genetic markers for body weight by GWAS in native cattle breeds of Indonesia. The Illumina Bovine 50K BeadChip was used to determine the candidate genes in three mixed-sex Indonesian cattle breeds of Bali (16 animals), Madura (16 animals), and Ongole grade (13 animals). All animals were raised at the Pasuruan Regency, East Java, Indonesia breeding station. The GWAS was performed in pooled sample of animals (45 animals) with the general linear model (GLM) method using SNP markers with minimum allele frequency (MAF) values more than 0.05 by TASSEL 5.0. software. Therefore, the body weight of cattle at 1 to 3 years of age was collected for each animal for computing Manhattan plot graphics. This research found that SUGT1, SF3A3, and DSCAM genes were detected as potential genetic markers for body weight in cattle breeds of Indonesia. The SUGT1 and DSCAM genes were monomorphic in Bali cattle (Bos javanicus). In addition, both genes were significantly associated (P

Objective Sumba Ongole (SO) cattle are valuable breed due to their important role in the development of Indonesian cattle. Despite rapid advances in molecular technology, no genomic studies on SO cattle have been conducted to date. The aim of this study is to provide genomic profile related to the population diversity, admixture, and demographic trends of SO cattle. Methods Genomic information was gathered from 79 SO cattle using the Illumina Bovine SNP50 v3 Beadchip, and for comparative purposes, additional genotypes from 209 cattle populations worldwide were included. The expected and observed heterozygosity, inbreeding coefficient, pairwise fixation indices between-population, and Nei's genetic distance were examined. Multidimensional scaling, admixture, and treemix analyses were used to investigate the population structure. Based on linkage disequilibrium and effective population size calculations, the demographic trend was observed. Results The findings indicated that the genetic diversity of SO cattle was similar to that of other indicine breeds. SO cattle were genetically related to indicines but not to taurines or Bali cattle. The study further confirmed the close relationship between SO, Ongole, and Nellore cattle. Additionally, a small portion of the Ongole mixture were identified dominant in the SO population at the moment. The study also discovered that SO and Bali cattle (Bos javanicus) could have been ancestors in the development of Ongole Grade cattle, which corresponds to the documented history of Ongolization. Our finding indicate that SO cattle have maintained stability and possess unique traits separate from their ancestors. Conclusion In conclusion, the genetic diversity of the SO cattle has been conserved as a result of the growing significance of the present demographic trend. Consistent endeavors are necessary to uphold the fitness of the breed.

Background: Booster vaccinations are a way to keep the body protected against COVID-19. Mojolangu Health Center is one of the densely populated areas which is part of the Lowokwaru sub-district and borders the Belimbing sub-district; the two sub-districts are ranked 2nd and 1st with the highest CFR (Case Fatality Rate) in Malang City. Therefore, examining public perceptions of vaccination to evaluate immunization programs and raise performance goals is essential. Purpose: To determine the relationship between the Health Belief Model components (perceived susceptibility, severity, benefits, barrier, and cues to action) and the participation of COVID-19 booster vaccination in survivors of COVID-19 aged ≥45 years. Conducted from April to November 2022, this research was located in the working area of Mojolangu Health Center (Mojolangu, Tunjungsekar, Tunggulwulung, and Tasikmadu village). Methods: This quantitative research used a case-control design study. This research sample comprised 82 people, selected using the purposive sampling technique with a 1:1 ratio for case and control. Data analysis was done using the Chi-Square test and Binary Logistics Regression tests. Results: The respondents were dominated by the middle age group (45-59 years), primarily entrepreneurs with a monthly income of more than IDR 3.5 million and domiciled in Mojolangu village. The perceived benefits variable showed p=0.04 (aOR=2.67; 95% CI=1.03-6.91) and perceived barriers p=0.01 (aOR=3.60; 95% CI=1.39-9.28), while perceived vulnerability p=1.00 (cOR=1.00; 95% CI= 0.32 – 3.16), perception of cues to act p= 0.18 (cOR= 1.82; 95% CI= 0.75 - 4.40). Conclusion: Factors related to booster vaccination participation are perceived benefits and barriers.

Abstract Kimchi, the traditional lactic fermented vegetables from Korea, is globally praised for its potential as a functional food owing to the presence of beneficial microorganisms known as probiotics. However, the serving of kimchi in traditional Korean dishes often involves cooking at high temperature, thus killing the probiotics. Recently, non-viable or inactivated microorganisms and their metabolites, known as postbiotics, were shown to confer health benefits when consumed, thus giving rise to a novel potential of kimchi as a postbiotic food with health functionalities. The present study aimed to explore the potential of uncooked and cooked kimchi, both as a probiotic and postbiotic food, respectively, using an animal model. Mice were fed by AIN-76 diet enriched in 10% freeze-dried uncooked or cooked kimchi for 28 days prior to kill. Several parameters related to immune system and antioxidant were evaluated. Exposure of kimchi toward heat in steaming process killed the microorganisms in kimchi, but did not alter its antioxidant activity. Interestingly, the consumption of uncooked and cooked kimchi stimulated the growth of lactic acid bacteria in the intestine indifferently, as shown in the fecal matter. In addition, kimchi supplementation, either uncooked or cooked, increased the number of splenic lymphocytes and intestinal IgA, supporting the role of kimchi in the immune system. Furthermore, kimchi supplementation reduced the level of lipid peroxidation in the fecal matter, indicating its antioxidant activity in vivo. Taken together, the findings in this study suggest the potential of kimchi both as a probiotic and postbiotic food with antioxidant and immunoenhancing properties.

Perintisan pendirian Taman Baca Masyarakat di desa muara telang marga kecamatan marga telang kabupaten banyuasin adalah program Pengabdian Kepada Masyarakat (PKM) UPBJJ-UT Palembang dengan menggunakan anggaran 2022. Pendirian Taman Baca Masyarakat ini bertujuan untuk meningkatkan minat minat baca masyarakat dan menjadi tempat belajar para pelajar dan anak-anak putus sekolah yang ada di desa muara marga telang khususnya dan di kecamatan muara telang pada umumnya. TBM merupakan sarana untuk pembelajaran dan pendidikan masyarakat secara nonformal. TBM diarahkan untuk memberikan pelayanan kepada warga masyarakat yang belum sekolah, buta aksara, putus sekolah, dan warga masyarakat yang kebutuhan pendidikannya tidak dapat terpenuhi melalui pendidikan formal. Perintisan TBM ini bertujuan meningkatkan literasai masyarakat sehingga dapat menciptakan masyarakat yang berdaya secara pengetahuan, ekonomi dan sosial.desa marga telang muara merupakan bagian daerah perarian yang memiliki keterbatasan akses perpustakaan secara fisik dan juga keterbatasan akses informasi digital dikarekan daerah ini masih belum tersedia jaringan internet yang memadai. Membangun literasi masyarakat pedesaan menjadi tanggung jawab perguruan tinggi sebagai salahsatu dari Tri Dharma Perguruan Tinggi. Metode yang dilakukan dalam pengabdian kepada masyarakat ini adalah Participatory Action Research (PAR), PAR merupakan penelitian yang melibatkan secara aktif semua pihak-pihak yang relevan (stakeholder) dalam mengkaji tindakan yang sedang berlangsung (dimana pengalaman mereka sendiri sebagai persoalan) dalam rangka melakukan perubahan dan perbaikan kearah yang lebih baik. Kegiatan ini akan dilakukan dengan tiga tahap yaitu persiapan, pelaksanaan dan monitoring. Pada persiapan tim abdimas akan membeli sarana dan prasarana yang dibutuhkan, tahap pelaksanaan tim akan menyerahkan baha-bahan dan akan memberikan materi terkait perpustakaan. Pada kegiatan monitoring tim akan mengevaluasi apakan TBM dimanfaatkan secara efektif dan efisien oleh masyarakat. Kegiatan perintisan pendirian taman baca masyarakat ini memberikan hasil berupa terwujudnya sebua taman baca masyarakat di desa muara telang marga sebagai upaya peningkatan literasi masyarakat dalam berbagai sector. Berdasarkan hasil evaluasi, dapat disimpulkan bahwa kegiatan pengabdian ini berhasil dalam mencapai tujuan yaitu meningkatnya minat baca masyarakat yang dapat dari penggunaan koleksi yang ada pada TBM baik membaca do tempat maupun dibawa pulang kerumah, hal ini dapat meningkatkan literasi masyarakat muara telang marga. Manfaat yang bisa diperoleh melalui kegiatan ini yaitu terjadi peningkatan lietasi masyarakat desa Muara Telang Marga.

The purpose of this study is to identify and analyze key factors of digital transformation of MSMEs in Magelang Regency Province using a prospective structured analysis approach. This research design is quantitative descriptive research. The type of data in this research uses primary data. The data source was obtained from Focus Group Discussion (FGD). The analysis method used prospective structural analysis techniques. The structural analysis was arranged in three stages, the first two stages were carried out during FGD and the third stage used MICMAC software. The variables that influence/determine (key drivers) the digital transformation of MSMEs in Magelang Regency are the key variables or factors of digital infrastructure, digital customer preferences, leadership and management and capital allocation. Transition variables include the innovation environment, technological mastery, environmental conditions and requirements, and human resources. Meanwhile, organizational culture is the dependent variable and company digital culture is an excluded variable. The digital infrastructure, innovation environment, and mastery of technology are the most influential variables, both directly between variables and indirect interactions.

People living with HIV/AIDS (PLWHA) can have better health outcomes with early identification of the AIDS phase. In the first three years, PLWHA may progress to the AIDS stage. This cross-sectional study aimed to determine the relationship between multimorbidity, nutritional status and duration of Antiretroviral (ARV) treatment on major signs of PLWHA. This study was conducted in the Intermediate and Infectious Disease Treatment Unit (UPIPI) at regional public hospital (RSUD) Dr. Soetomo Surabaya from January to February 2023. As many as 52 PLWHA who started HIV treatment at RSUD Dr. Soetomo in 2020 to 2021 were sampled in this study, which was obtained from medical records. The dependent variable in this study was the major sign of HIV. Independent variables in this study were multimorbidity, nutritional status, and the duration of ARV treatment. This study found that 76.9% of PLWHA experienced major signs. Multimorbidity and duration of ARV treatment did not have an association with major signs of HIV (p-value > 0.05). Nutritional status has a significant association with major clinical symptoms of HIV (p-value < 0.05). PLWHA with underweight had higher odds of having a major sign (p-value = 0.017; PR = 1.507; 95% CI 1.131-2.008) than PLWHA with normal nutritional status. Thereby, it is hoped that the hospital will be assisted in determining health promotion needs such as screening and evaluation of nutritional status to monitor the nutritional status of patients, which will improve their health outcomes.

Objective: To assess the correlation between vitamin D levels, dysmenorrhea intensity measured by the visual analogue scale (VAS), and the stage of endometriosis determined by the American Society of Reproductive Medicine (ASRM) grading score. Methods: A cross-sectional study was conducted involving 37 women diagnosed with suspected endometriosis who met the inclusion and exclusion criteria. The aim was to determine the correlation between vitamin D levels, dysmenorrhea VAS scores, and the ASRM endometriosis stage at RSUP Dr. Mohammad Hoesin Palembang from November 2021 to April 2022. Bivariate analysis was employed to assess correlation, utilizing Pearson's correlation test and the Spearman Rank correlation test as an alternative method. Results: There was a significant positive correlation between vitamin D levels and the VAS score for dysmenorrhea (r = 0.678; p = 0.000) and a very strong positive correlation between vitamin D levels and the degree of endometriosis (r = 0.774; p = 0.000) based on Spearman Rho's correlation test. Conclusion: There is a significant relationship between vitamin D levels with the VAS score of dysmenorrhea and the degree of endometriosis ASRM. Keywords: american society of reproductive medicine, endometriosis, visual analogue scale, vitamin D

One of the problems students often face is the lack of understanding of their interests and talents which will cause confusion in making future study choices and career plans. Career selection is an expression of personality into the world of work followed by identification of certain occupational stereotypes. Eight intelligences according to dr. Howard Gardner is linguistic, logical, mathematical, visual spatial, musical, kinesthetic, interpersonal, intrapersonal, and naturalist. This research purpose is to develop a system that produces information and professional recommendations that are in accordance with multiple intelligences of prospective high school students using a combination of Bayes' theorem and weighted product (WP) method. User’s preference value is calculated using the Bayes Theorem method to give each multiple intelligence value which is a criterion. WP method calculation to find professions that match user preferences. Weight of each criterion needed in WP method is calculated by Rank Order Centroid method. WP calculation will produce a ranking of 3 professions according to the input from the user. From system testing results that compared to results from experts, an accuracy of 67.33% is obtained. Based on the accuracy value, it can be said that the accuracy level system is quite good.

Latar Belakang: Salah satu permasalahan yang sering dihadapi para peternak Itik Manila saat ini yaitu mahalnya harga pakan dan tingkat pertumbuhan yang tidak stabil. Hal tersebut menyebabkan pertumbuhan bobot badan Itik Manila tidak maksimal dan berdampak terhadap persentase karkas yang tidak sesuai dengan harapan. Daun pepaya merupakan salah satu jenis limbah dari usaha pertanian yang dapat jadikan sebagai pakan tambahan dengan cara diubah menjadi tepung yang dicampur dengan pakan. Tepung daun pepaya mengandung protein, kalsium dan phosphor, serta mampu meningkatkan produktivitas karkas ternak Itik Manila. Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh penambahan tepung daun pepaya dalam pakan terhadap persentase karkas bagian dada dan paha Itik Manila. Metode: Penelitian ini menggunakan materi 40 ekor ternak Itik Manila berumur enam minggu, metode yang digunakan yaitu Rancangan Acak Lengkap (RAL) yang terdiri dari 4 perlakuan dan 5 ulangan. Perlakuan terdiri dari penambahan tepung daun pepaya PO 0%, P1 3%, P2 5% dan P3 7%. Hasil: Hasil penelitian menunjukkan bahwa penambahan tepung daun pepaya dalam pakan berpengaruh sangat nyata (P

This article discusses about the importance of the investigation of overeating topic to be examined, since it has caused a lot of victims. The main causes to it are obesity, cardiovascular, and bad diet. The prophet salallahu ‘alaihi wassalam (d.11 H) had given hadith about the correct and appropriate way on eating and drinking. This problem has become the question as well as the purpose of this hadith. This article hinges on the quality and the quantity of the hadith prohibiting Binge Eating Disorder in Sigmund Freud’s Psychoanalytic Perspective. The method of data collection in this study is library research which involves the review of primary book and its syarah. The supported resources are derived from journal article, book, and relevant literature. Data was analysed by using Psychoanalytic perspective of Sigmund Freud. The result shows that this hadith can be classified as marfu` qauli with the narration of Bil Ma’na. Ibnu Mājah’s narration is Mubham, which means there is no irregularities in this type of sanad, hence: this hadith is not fulfilling the ṣaḥīḥ criteria, or this hadith can be grouped as ḍa`īf. However, according to imam Tirmiżi and imam Aḥmad bin Hanbal, the two sanad are considered as having no irregularities, so that this hadith can then be claimed as ḥasan li ghairihi. The quantity of this hadith is Ahad with absolute gharib category due to its single narration of its beginning of the sanad (the companion Miqdam bin Ma’di Karib). The matan of hadith narrated by Miqdam bin Ma’di Karib consists of advice and recommendation for human to be able to manage uncontrollable willing (Id). The strong willing is controlled by ego, and it is supposed to be submitted to the commands of the superego/moral. All of the three are parts of the conscious mind and the unconscious mind of Sigmund Freud’s psychoanalytic. In addition, Binge Eating Disorder (BED) can be derived from emotional eating, mindless eating, and kuchisabishi.

This research aims to produce a digital lower passing test tool based on an Android application at SMP Negeri 55 Palembang. The type of research used is research and development (R&D), which is research that produces a product in the form of a digital lower passing test tool based on an Android application. The sampling technique in this research was all students in class VII of SMP Negeri 55 Palembang who at that time were studying bottom passing material in learning the game of volleyball. The data collection techniques used are product validity test data, practicality tests and effectiveness tests. The instruments in this research were validation sheets, questionnaires and students' passing tests. The data analysis technique is validity analysis, practicality analysis and effectiveness analysis. Based on the research results, it can be concluded from the research that the bottom passing test tool is said to be very valid, seen from the validator research results, namely an average percentage of 95% with a very valid category. Based on the student response questionnaire, this lower passing test tool is said to be practical to use with a score of 3.83 with a very positive classification. Based on the results of the bottom passing test, using this tool is effective for use in the learning process. The results of the lower passing test were obtained with an average of 16 in the high category. The conclusion of this research is that the Android application-based digital passing test tool is declared to be very valid in its use, this tool is also practical to use, and this tool is effectively used as a support for learning activities in the game of volleyball. The implementation of the results of this research is that the Android application-based digital passing test tool can be used as intended.

Penelitian ini bertujuan untuk mengetahui tingkat validitas dan respon peserta didik terhadap media interactive book pada materi larutan elektrolit dan nonelektrolit. Penelitian ini menggunakan metode penelitian dan pengembangan (R&D) dengan model Borg and Gall. Instrumen pengumpul data berupa angket validasi media dan angket respon peserta didik. Data yang diperoleh dari validasi media dihitung menggunakan rumus indeks Aiken V dan data yang diperoleh dari peserta didik dihitung dengan cara mengalikan skor yang diperoleh dengan angka 4, kemudian dibagi dengan skor maksimumnya. Subyek dalam penelitian ini adalah 9 peserta didik kelas X MA Raudhatusysyubban, 2 dosen program studi pendidikan kimia UNISKA dan 1 guru kimia MA Raudhatusysyubban. Hasil penelitian menunjukkan bahwa tingkat validitas media interactive book berada pada kategori valid dan mendapat respon yang sangat baik dari peserta didik sebagai pengguna. Dengan demikian, media interactive book ini dapat digunakan sebagai media pembelajaran pada materi larutan elektrolit dan nonelektrolit.

Introduction:Young people in Indonesia persistently grapple with nutritional challenges. Regrettably, there has been insufficient research addressing their distinct nutritional requirements. Objective:This study aims to describe the dietary diversity of female students in Southeast Sulawesi and investigate the associated factors. Methods:A cross-sectional study was conducted among female students in the Public Health Faculty of Halu Oleo University. Using random sampling, 280 participants were selected from five different departments within the faculty. Minimum dietary diversity for women (MDD-W) was assessed using a single 24-hour recall. A cut-off value of 5 was used to determine whether the recommendation was met. Multiple logistic regression was performed to examine the association between independent variables and MDD-W. Results:The mean (±SD) dietary diversity score of the participants was 3.6±1.1, with only 33.3% meeting the minimum recommendation for dietary diversity. In the multivariate analysis, higher maternal education (AOR: 4.4; 95% CI: 2.0, 9.6), higher paternal education (AOR: 3.2; 95% CI: 1.2, 8.2), and monthly food budget (AOR: 1.9; 95% CI: 1.0, 3.7) were significantly associated with achieving adequate dietary diversity.

Dideng is an oral art from Rantau Pandan Village whose existence is of concern due to the lack of regeneration. In fact, Dideng art has theatrical, musical and gestural power. The content of Dideng is the legend of Puti Dayang Ayu which has great dramatic potential. Designing a performance concept (dramaturgical design) based on the legend of Puti Dayang Ayu is an effort to revitalize and develop Jambi's dramatic arts. This research aims to find dramatic material to then reassemble into a dramaturgical plan based on the legend of Dideng Puti Dayang Ayu. This research uses a qualitative method with a case study approach. The data collection techniques used were interviews and observation. Data analysis was carried out using three analytical tools, namely data reduction, data presentation, and drawing conclusions. The results achieved from this research are 1). Dideng is a means of entertainment for the people of Rantau Pandan village which does not yet have a good regeneration of speakers. Therefore, creativity is needed to create Dideng in more attractive packaging. 2). The Dideng text was passed down orally so it does not have a standard story. Each speaker has their own version of the story. Therefore, the preparation of the story is adjusted to the dramatic needs of the story. 3). The writing of this play was motivated by the dramatic vision of "rationalization of legend". The main theme is broken promises and is structured in an aristolelian episodic plot.

Introduction: One of the keys to success in efforts to overcome the COVID-19 pandemic is to comply with health protocols. The COVID-19 health protocol compliance level is known to be low in the adolescent age group. The low level of compliance is related to the role of Karang Taruna as a village-level organization in providing education and examples to their peers, namely adolescents. Aims: This study was conducted to describe the level of compliance of Karang Taruna members in Pandanlandung Village, Wagir District, Malang Regency to the COVID-19 Health Protocol. Methods: The design used in this research is cross sectional with a quantitative descriptive method. This research was conducted in March-October 2021 with the number of respondents as many as 24 members of the Karang Taruna Pandanlandung Village who were selected using a total sampling technique. Results: This research study found that the compliance level of members of the Karang Taruna Pandanlandung Village was in the "Good" category, especially in the aspects of "Using Masks" 70.83%, "Washing Hands" 79.17%, "Avoiding Crowds" 50% and "Limiting Mobility" 50%. Conclusion: from this study is that, in general, the implementation of the COVID-19 health protocol is good, but the implementation of health protocols in daily life must still be improved by reminding fellow members of Karang Taruna to continue to carry out the health protocol because the pandemic is not over so as to reduce the transmission rate of COVID-19.

Halal food assurance is becoming more important with the growth of the halal industry globally. Adulteration of halal meat products using non-halal sources such as pork, dog, boar, and even frog meat has become a major problem for moslems. The purpose of this study is to initiate the method for frog meat identification using polymerase chain reaction (PCR) technique. In this study, three primer pairs (Fk1-Rk1, Fk2-Rk2, Fk3-Rk3) were analyzed for their specificity toward frog meat against other common halal meat sources such as beef, chicken, shrimp, squid, and mackerel. The visualization of DNA amplification showed that primer pair Fk1-Rk1 produced primer-dimer, thus cannot be used for this circumstance. Primer pair Fk2-Rk2 showed a better result where DNA amplicon was produced at ~100 bp for frog meat and no amplicons for other meat. Primer pair Fk3-Rk3 showed a different pattern of DNA amplification for all the meat tested, where the amplicon of frog meat was shown at ~100 bp, while the other meat showed multiple amplicons or none. In conclusion, primer pairs Fk2-Rk2 and Fk3-Rk3 showed their potential as primer pairs for frog meat identification using PCR for implementing halal food assurance, although sensitivity analysis needs to be investigated.

This study aims to determine the physical activity of volleyball players at Indralaya Utara 2 Junior High School.This research is quantitative research with a descriptive research design.The subjects of this study were volleyball players at Indralaya Utara 2 Junior High School with a total of 30 players consisting of 22 boys and 8 girls.Data collection used a test.The research location was carried out in an outdoor laboratory in the University Education Park.The data analysis technique uses descriptive analysis, which is expressed in the form of a percentage.The results of the study found that the physical activity of volleyball players which included endurance, speed, arm muscle strength, abdominal muscle strength, and leg muscle explosive power was in the moderate category and there were 3 players in the very good category, 6 players in the good category, 11 players in the fair category, 9 players in the poor category, 1 player in the very poor category.It can be concluded that the physical activity of volleyball players at Indralaya Utara 2 Junior High School is in the sufficient category. some of the findings have implications for the results of the research, namely the emergence of awareness for both players and students to increase and maintain physical activity wherever and whenever to improve the physical condition of players who are still in the sufficient category and still not enough so they can get better.

Hyperglycemia is one of the causes of diabetes mellitus. One example of a plant used as an anti-hyperglycemic and anti-diabetic herbal medicine is the mahogany plant (Swietenia mahagoni). Drugs in nanoemulsion dosages must be developed to increase oral bioavailability and drug solubility from herbal plant extracts. So, research was carried out to determine the formulation and optimization of nanoemulsion from mahogany seed extract (Swietenia mahagoni) and its effect on reducing blood glucose levels in mice (Mus musculus L.). Based on research that has been carried out, the nanoemulsion formula for mahogany seed extract is characterized by a transmittance percentage of 84.7 % and a particle size of 12.21 nm. Administration of mahogany seed extract and nanoemulsion formulation of mahogany seed extract (Swietenia mahagoni) can reduce blood glucose levels in hyperglycemic mice (Mus musculus L.). Further, a computational analysis using the molecular docking approach was carried out to analyze the molecular interaction between the main components of mahogany seed (glycidyl oleate and glycidyl palmitoleate) and alpha-glucosidase. The outcome suggested that these substances are bonded to the alpha-glucosidase catalytic sites by hydrogen bonding and hydrophobic interactions and are stable during MD simulation, suggesting that the primary components of mahogany seed may become potential alpha-glucosidase inhibitors to treat diabetes.

Kelurahan Sako Baru terbentuk Tanggal 18 Agustus 2007. Kelurahan Sako Baru memiliki Bank sampah yang bernama “Bank Sampah Melati”. Kelurahan Sako Baru juda terdapat salah Satu Prioritas Program PKK Sako Baru adalah Pengembangan Kehidupan Berkoperasi. Adapun Pelaksanaan Programnya adalah Pemberian keterampilan keluarga dalam upaya peningkatan dan pemberdayaan ekonomi kelurga melalui pengembangan ekonomi kreatif dan usaha mikro kecil, serta pengembangan kehidupan berkoperasi. Pelatihan Pembuatan Bunga Hias dari Sampah Plastik Bank Sampah Melati PKK Kelurahan Sako Baru dapat menghasilkan produk-produk kreativitas atau produk inovatif yang mudah dikerjakan dan dipasarkan. Metode Pengabdian yang digunakan adalah Participatory Action Research (PAR) Dari data yang kami peroleh dari Kelurahan Sako Baru termasuk warga yang tingkat pendapatannya rata-rata rendah. Selanjutnya juga berdasarkan hasil wawancara di lapangan sebagian besar wanita Kelurahan Sako Baru tidak bekerja, ataupun bekerja musiman, ibu rumah tangga sehingga sangat menunjang apabila diberikan tambahan keterampilan untuk “Pelatihan Membuat Bunga Hias dari Sampah Plastik“. Dengan demikian kegiatan PKM ini dapat mengembangkan kewirausahaan Kelurahan Sako Baru dan meningkatkan keterampilan PKK dalam membuat Bunga Plastik dari sampah kresek plastik yang siap dipasarkan. Metode pelaksanaan diawali dengan pemberian penyuluhan, Sosialisasi, pelatihan, praktik, dan penilaian bagaimana layaknya barang untuk dipasarkan. Harapan dari PKM ini adalah adanya peningkatan ekonomi dikalangan keluarga melalui pemanfaatan lingkungan sebagai sumber penghasilan masyarakat.

Cucurbitaceae is known as a source of vegetable oil that can be used in the fields of food, medicine, and cosmetics. Several studies showed that vegetable oil from the Cucurbitaceae contains squalene. Squalene is a high-economic value compound that was originally found in shark liver oil. This compound is proven to be very beneficial for health and cosmetics. The objectives of the study are to determine the fatty acid profile and squalene content of cucumber seed oil using the Gas Chromatography-Mass Spectrometry (GC-MS) method. Starting with the preparation of cucumber seeds by drying the clean seed in an oven at 60 0C for 1 hour, then the seeds were extracted using 2 methods namely maceration and a continuous extraction method with a soxhlet extractor. The yield of crude oil obtained by the soxhlet extractor is higher than maceration, which was 19.38 ± 0.94%, yellow colour, and distinct aroma, 2% water oil content; oil density of 0.96 g/mL; free fatty acid levels of 3.51%; an acid value of 4.97 mg NaOH/g oil; and peroxide value of 0.82 meq O2/g oil. The results of the GC-MS analysis showed that cucumber oil was composed of 3 main components namely palmitic acid, linoleic acid, and squalene. Keywords: Cucumber seed oil, Cucumis sativus, fatty acids, squalene.

Pneumonia cases in West Java Province 2018 were ranked first as the province with the highest number of cases in Indonesia with a prevalence of 58.80%. About 7-13% of severe pneumonia patients with an increased risk of death in children require intensive care. This study aims to determine the relationship between host and environmental factors on the severity of pneumonia in children under five years. The research method used cross-sectional study design approach. Data analysis techniques used chi-square, fisher's exact, and multiple logistic regression tests. The population in this study was 2,338 children under five years aged 12-59 months in West Java Province for the 2018 period, while the sample consisted of 132 respondents who met the inclusion criteria and were recorded in RISKESDAS 2018. The results showed that there was a significant relationship between host factors and the severity of pneumonia, namely prematurity (aOR= 2.446; 95% CI=1.113-5.376), while environmental factors that have a significant relationship on the severity of pneumonia, namely the habit of opening windows (aOR= 2.963; 95% CI=1.342-6.544). There is no relationship between Low Birth Weight (LBW), home ventilation conditions and lighting intensity. The most dominant factor in the severity of pneumonia is that the habit of opening windows does not meet the risk of 2.9 times higher severity of pneumonia in children under five years. This study concludes a relationship between prematurity and the habit of opening windows on the severity of pneumonia.

The aim of this study is to improve soil fertility in cassava, corn, and peanut plants by using biochar technology on degraded land. This research is experimental. This trial used five treatments, No organic amendments, farm yard manure (FYM) 20 Mg ha−1 once, FYM 20 Mg ha−1 yearly, FYM biochar technology 15 Mg ha−1 once, and cassava stem (CS) biochar technology 15 Mg ha−1 once. The design used in this study was a randomized group design (RAK) with three repeats. Before the experiment, the characteristics of treatment material, namely, the manure, biochar, and CS waste biochar were studied. It was observed that cassava, corn, and peanut crops increased nutrient C, water availability, N, P, K, and cation exchange capacity (CEC). From the observations, the treatment of using biochar technology on intercropping cassava and corn can increase C by 25.7 g kg−1, K by 177 cmol, CEC by 17.63 cmol , and water availability by16.87%. Meanwhile, the application treatment of biochar FYM technology on cassava and peanut intercropping can increase C by 24.4 g kg−1, N by 1.3 g kg−1, P by 12.2 g kg−1, K by 1.74 cmol, CEC by 17.93 cmol, and water availability by 17.41%. The use of biochar technology (15 Mg ha)−1 in intercropping cassava with maize or groundnut within 2 years can improve soil fertility and maintain yields. Intercropping cassava with corn or peanuts within 2 years can increase soil fertility and maintain crop yields. Thus, biochar technology has greater potential for the improvement of degraded land in the relatively short term (2 years) and supports sustainable agriculture.

Genetic characterization in native livestock is essential to conserve the genetics standard of livestock for pure-breeding programs. This research aimed to characterize four Indonesian cattle breeds using 156 sites of Parentage SNP Markers, includingARS-USMARC-Parent (119 sites) and ARS-USMARC (37 sites). Total of 113 mixed-sex animals were used for the evaluation, including 16 Bali (Bos javanicus), 16 Madura (Bos indicus), 33 Ongole grade (Bos indicus), and 48 Sumba Ongole (Bos indicus) cattle breeds. Results showed Bali, Madura, and Ongole lineage (Ongole grade and Sumba Ongole) cattle can be discriminated against with the Parentage SNP Markers. The pairwise genetic distance analysis revealed that Bali cattle had a closer genetic relationship with Madura cattle (0.043 - 0.151) than Ongole lineage cattle (0.073 - 0.325). However, the phylogenetic tree explained that the Ongole lineage cattle are grouped into two different clades. At the same time, Bali, Madura and Ongole lineage cattle are grouped into their original cluster. The study suggests that the Parentage SNP Markers can be used to characterize Bali, Madura, and Ongole lineage cattle accurately.

Morphostructural characterization can be used to identify unique characteristics in different animal breeds and an essential tool for the identification and classification of these breeds. The objective of this study was to characterize four Indonesian goat breeds based on their morphostructural traits. A total of 315 female goats (does) at 2.5 - 3.5 years of age were used currently and consisted of 28 Boer, 118 Boerka, 141 Kacang and 28 Ettawa cross. Total eleven body measurements and ten body conformations were measured to describe the morphostructure of goats. Two statistical methods of canonical discriminant analysis (CDA) and hierarchical cluster analysis (HCA) were used to differentiate goat breeds. Body measurement and body index were able to discriminate goat breeds with canonical correlation (Function 1) of 0.81 and 0.77, respectively. According to HCA of morphostructural traits, Boerka and Kacang does are classified into similar cluster. Body measurement is better for discriminating goat breeds rather than body conformation.

Endometriosis merupakan kondisi kronik dimana terjadi implantasi jaringan fungsional endometrium di luar kavum uterus.Diagnosis endometriosis cukup sulit dan sering tidak terdeteksi dalam waktu lama sehingga penelitian ini bertujuan untuk membantu penegakkan diagnosis lebih cepat karena dapat memperkirakan lokasi lesi lebih awal. Penelitian ini berjenis observasional analitik dengan pendekatan cross sectional dengan jumlah sampel berjumlah 102 pasien. Lokasi perlengketan terbanyak berada di uterus sebanyak 54 pasien (52,9%) dan gejala klinis yang paling banyak adalah dismenore yaitu sebanyak 71 pasien (69,6%). Hubungan gejala dismenore dengan lokasi perlengketan di uterus didapatkan nilai p sebesar 0,732 dan hubungan gejala dispareunia dengan lokasi perlengketan di cul de sac didapatkan nilai p sebesar 0,525. Sedangkan penelitian tentang hubungan antara gejala klinis diskezia dengan lokasi di rektum menghasilkan nilai p value 0,031 dan nilai PR 10,90 (95% CI 1,19 – 99,78). Tidak ada hubungan yang bermakna antara gejala klinis dismenore dengan letak perlengketan di uterus dan hubungan antara gejala klinis dispareunia dengan letak perlengketan di cul de sac. Namun, terdapat hubungan antara gejala klinis diskezia dan lokasi perlengketan di rektum.

This study aims to determine the impact of running speed and limb muscle strength on the squat-style long jump results of State Senior High School students. The participants of this study were 40 people. The data collection technique for measuring speed was the 40-meter sprint test, for measuring limb muscle strength, namely the standing broad jump test, and for measuring the long jump style squat, namely the long jump style squat test. Data analysis techniques to find out the relationship between (X1, Y) and (X2, Y) used the Product Moment Correlation Formula. The Linearity Test was intended to test whether the data obtained is linear or not. If the data is linear, then it can be continued with the regression technique. The finding concludes that the three variables have a significant value that is less than 0.05 (significant value 0.05). The multiple correlations (R) between the independent variable and the dependent variable have a significant relationship because of F-count (18.5) ≤ F-table (37). This means that there is a contribution to the relationship between running speed and limb muscle strength with the results of the squat-style long jump. So, schools can take advantage of the results of this research as one of the considerations for providing facilities for long jump activities and providing teaching materials for sports teachers.

The discovery of new peptides and their derivatives is an outcome of ongoing efforts to identify a peptide with significant biological activity for effective usage as a possible therapeutic agent. Spinorphin peptides have been documented to exhibit numerous applications and features. In this study, biologically active peptide derivatives based on novel peptide analogues of spinorphin conjugated with 5,5′-dimethyl (Dm) and 5,5′-diphenyl (Ph) hydantoin derivatives have been successfully synthesized and characterized. Scanning electron microscopy (SEM) and spectral methods such as UV-Vis, FT-IR (Fourier Transform Infrared Spectroscopy), CD (Circular Dichroism), and fluorimetry were used to characterize the microstructure of the resulting compounds. The results revealed changes in peptide morphology as a result of the restructuring of the aminoacidic sequences and aromatic bonds, which is related to the formation of intermolecular hydrogen bonds between tyrosyl groups and the hydantoin moiety. Electrochemical and fluorescence approaches were used to determine some physicochemical parameters related to the biological behavior of the compounds. The biological properties of the spinorphin derivatives were evaluated in vivo for anticonvulsant activity against the psychomotor seizures at different doses of the studied peptides. Both spinorphin analog peptides with Ph and Dm groups showed activity against all three phases of the seizure in the intravenous Pentylenetetrazole Seizure (ivPTZ) test. This suggests that hydantoin residues do not play a crucial role in the structure of spinorphin compounds and in determining the potency to raise the seizure threshold. On the other hand, analogs with a phenytoin residue are active against the drug-resistant epilepsy test (6-Hz test). In addition, bioactivity analyses revealed that the new peptide analogues have the potential to be used as antimicrobial and antioxidant compounds. These findings suggest promising avenues for further research that may lead to the development of alternative medicines or applications in various fields beyond epilepsy treatment.

A high humidity level in the environment leads to the development of desiccants as hygroscopic material for adsorbing water vapor. Mesoporous silica xerogel, one of the solid adsorbents used for humidity adsorption, was synthesized from hazardous waste of volcanic mud via sol–gel methods by controlling the pH of the solution. The disordered amorphous silica was obtained, with the properties varied depending on the pH of the solution. Silica xerogel obtained at pH 8 exhibits the highest specific surface area of 576.527 m2g−1 and mesoporous surface area of 527.842 m2g−1. It also has the highest adsorption capacity of 18.90% gw/gads determined from the conventional method and 22.14% gw/gads from TG analysis. The performance for humidity adsorption exceeds the commercial silica with an efficiency of 0.9–7% gw/gads. This result indicates that the potential SiO2 extracted from volcanic mud can be commercialized as desiccants for humidity adsorption.

Nata merupakan salah satu jenis pangan funsgional yang dapat dimanfaatkan sebagai sumber nutrisi magi masyarakat. Nata merupakan kumpulan selulosa yang berbentuk menjadi lembaran bertekstur kenyal, berwarna putih, serta mengapung pada substrat cairan air kelapa. Bahan utama yang sering digunakan dalam membuat nata adalah air kelapa dengan berbantuan bakteri Acetobacter xylinum serta sederetan proses pembuatan secara steril. Pada umumnya nata de coco dibuat dengan bantuan urea, namun tidak pada pengabdian masyarakat ini. Nata yang dihasilkan bebas dari zat kimia melainkan menggunakan ekstrak toge biji kacang hijau. Proses ini penting untuk diinformasikan kepada masyarakat khususnya ibu-ibu PKK Rias Dana Desa Pangestu Kecamatan Makarti Jaya Kabupaten Banyuasin. Metode yang digunakan dalam kegiatan ini meliputi ceramah, praktek dan evaluasi. Survei mitra menunjukkan bahwa mitra sangat memahami proses pembuatan nata de coco dan sudah mencoba secara mandiri dalam proses pembuatannta.

This study aims to analyze the factors that influence the production of superior variety rice seed farming, the level of technical efficiency of superior variety rice seed farming and analyze the factors affecting the level of technical inefficiency of rice seed breeders of superior variety in Tabalong Regency. This research was conducted in the Districts of Jaro, Muara Uya and Benua Lawas, Tabalong Regency, starting from October 2022-January 2023. The analytical tool used is the frontier stochastic approach with the Ordinary Least Square (OLS) method. The results showed that the production of superior varieties of rice seed farming in Tabalong Regency, South Kalimantan Province was significantly influenced at a 1% significant level by organic fertilizers, inorganic fertilizers, pesticides, and labor, while land area was significantly affected at 5% significant level. The average technical efficiency value at the research location is 0.8742. The factors of technical inefficiency, length of farming and level of education have a negative effect on the level of technical inefficiency.

This research aims to analyze the performance of creative and productive learning strategies in the subject of Physical Education and Health (PJOK) for 10th-grade students at SMAN 5 Sekayu. The population of this study consists of 10th-grade students at SMAN 5 Sekayu. The qualitative descriptive method was employed, and the sampling technique used in this study was total sampling, where the entire population was included as the sample, resulting in 35 respondents. Data collection techniques included questionnaires, interviews, and documentation. Data analysis techniques involved data reduction, data presentation, and drawing conclusions. Based on the research findings, it can be concluded that the creative and productive learning strategies in the PJOK subject for 10th-grade students at SMAN 5 Sekayu are categorized as highly effective, accounting for 82.4%. The conclusion of this study is that the analysis of creative and productive learning strategies in the PJOK subject for 10th-grade students at SMAN 5 Sekayu falls under the category of excellent. The implication is that these strategies can be adopted and implemented in other subjects at the same school or similar institutions.

Hadith is the second source of Islamic knowledge after the Quran. This means that hadith covers all aspects of activities that can be used as a reference, including education and the sciences that it encompasses. The problem in the world of education today is that teachers and students are forced to use a limited range of learning methods. This condition is caused by the lack of activities and creativity that educators and students engage in during the learning process. This situation has occurred during the time of the Prophet Muhammad, and hadiths related to avoiding boredom in learning have emerged. From this issue, research objectives were established. The purpose of this research is to determine the quality, quantity, and meaning of hadiths related to avoiding boredom in learning from the perspective of educational psychology that is adjusted to teaching strategies. The method used in this study is literature review (pentakhrijan hadith). The results of the study indicate that (1) the hadith "avoiding boredom in learning" is narrated by four mukharij (Bukhari, Muslim, Tirmidhi, and Ahmad) with thirteen sanad that are ṡiqah, connected by the year of death, place of residence, and teacher and student. Thus, this hadith can be categorized as a ṣahih li żātihi hadith. The quantity of this hadith is included as a Hadith Ahad with a garib category, (2) the meaning of this hadith can be related to educational psychology, because the habit of the Prophet in choosing the right day to provide appropriate education based on educational psychology.

Indonesia is one of the countries that contribute the most mortality of TB in the world. The tuberculosis treatment success rate in Indonesia is 86% meanwhile is still far from the target coverage of the TB treatment success rate (90%). This study conducted to determine the determinant factors of successful TB treatment in Puskesmas Singosari. A cross-sectional design study was constructed for this study and used SITB and form TB as a research instrument. The population of this study were all drug-susceptible TB patients who had completed treatment at the Puskesmas Singosari in 2020, 2021, and QI-QII in 2022. The sample of this study was 71 people from 99 total population. The dependent variable is the success of drug-susceptible TB treatment. Independent variables are sex, age, weight, regular use of anti-tuberculosis drugs, and comorbidities. The data processing and analysis are being conducted using SPSS software. Chi-square analysis showed that the variable weight changes have a significant assosiation to successful tuberculosis treatment (p = 0,014; OR = 9,818). Puskesmas Singosari's TB Team can collaborate with the nutritionist team to optimize TB treatment by monitoring nutritional status and weight gain of drug-susceptible TB patients.

Sumba Ongole (Bos indicus) is a native beef cattle that adapts well in Sumba Island of Indonesia. This study was carried out to perform a genome-wide association study for body weight (BW) and carcass weight (CW) in Sumba Ongole (SO) bulls. A total of forty-eight (n=48) SO bulls were used in this study. The data were collected from the slaughterhouse at Bogor City, West Java, Indonesia, and were analyzed using a genomic software of TASSEL 5.0 to obtain the best genetic marker. The result showed that the threshold Manhattan plot (-Log10P3) was used to select SNP markers for BW and CW in SO bulls. The two (2) SNP markers at BTA1, i.e., ARS-BFGL-NGS-3162 (CEP63 gene) and ARS-BFGL-NGS-78232 were significantly associated with BW and CW, respectively. Nonetheless, the genetic diversity in both SNP markers was low, with a PIC value of less than 0.30. In conclusion, the heterozygous TG bulls in CEP63 gene have higher CW than homozygous TT bulls.

Study purpose. Physical education, sports and health for elementary school students are oriented to learning locomotor movements, so learning these skills requires fun activities, such as games. This research aims to develop a basic locomotor learning model based on a small game competition for elementary school students. Materials and methods. This study used a research and development approach using ADDIE model. This research was carried out in three elementary schools, namely: Elementary school 22 Gelumbang, Elementary school 11 Gelumbang and Elementary school 2 Lembak. Data were collected using observation, interview, questionnaire, and test. The questionnaire instrument used in this study was the Guttman scale questionnaire because of using the Guttman scale. Expert judgments were used to analyze the product. Results. The model can be applied in all elementary schools in the territory of Indonesia because product development has referred to competencies and learning outcomes in the 2013 curriculum. There are four types of games that have been developed for learning locomotor skills, namely 1) jump rope game, 2) watch out for crocodiles, 3) continuous running game, and 4) box jump game. Each game has different locomotor skill movements, including walk, run, slide, leap, gallop, skip, jump, and hop. Based on the effectiveness aspect, the results of the product trial show that the ‘wary crocodile game’ is a game that is in great demand and favored by students. Conclusions. The locomotor skills learning model for elementary school students based on small game competitions has been feasible and effective for use in sports and health physical education classes. This model can also be applied in all elementary schools in the territory of Indonesia because product development has referred to competencies and learning outcomes in the 2013 curriculum.

This study aims to analyze the substance of the Covid-19 vaccine certificate policy as an administrative requirement in Jambi City and the regional government’s authority in enforcing the Covid-19 vaccine certificate policy in Jambi City. This study uses an empirical legal approach with a descriptive research type. Data collection techniques using interviews, observation, and documentation. Source of data used in the form of primary data and secondary data. The data that has been obtained is analyzed systematically. The results of the study show that the Covid-19 vaccine certificate policy as an administrative requirement for entering public places regulated through the Mayor of Jambi Circular Letter Number PW.01/441/DPK/2021 must be pursued into a Regional Regulation so that the substance has strong binding power. The Regional Government of Jambi City in enforcing the Covid-19 vaccine certificate policy has the authority to disseminate information to the community and carry out a real monitoring function as a means to evaluate the performance of implementing the Covid-19 vaccine certificate in public places or public spaces.

Abstract A series of treatments were designed to evaluate the efficacy of feeding commercial multispecies probiotics feeding with enzymes and fermentation process on the growth parameters and culture environment of Pacific white shrimp, Litopenaeus vannamei (Boone, 1931), in an intensive culture system. Commercial multispecies probiotics and enzymes (PEs) were continuously applied in three different doses, namely (i) 0.2, (ii) 0.4, and (iii) 0.6 mg L−1 and designated as 0.2, 0.4, and 0.6 PE during the first 30 days of intensive culture of Pacific white shrimp, L. vannamei (Boone, 1931). The probiotics were continually applied every alternate day, while the enzymes were added every sixth day throughout the trial period. The PE dose for all treated tanks was increased by 0.2 ppm after 30 days of culture and another 0.2 ppm after day 60. Meanwhile, fermentation technique, which has become the common method applied in Indonesia in the control treatment, was added on the same day with the PE group with increasing dosage, following the same trend with the 0.6 PE group. Results showed that the group receiving 0.6 PE showed higher final biomass, higher mean weight, and protein retention efficiency as well as a lower feed conversion ratio compared with the control treatment. Abundance of Vibrio spp. remained below 103 cfu mL−1 throughout the trial. Water quality indicators TAN, NO2N and NO3N peaked in weeks 3–5 and then declined after that until the end of the culture period in all tanks. This decline was significantly faster in PE‐treated tanks. Multispecies PEs have potential applications in controlling Vibrio spp., maintaining proper water quality condition, and enhancing the growth of shrimp in intensive culture system.