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9 results on '"Hardy, Patricia"'

1. A Randomized Trial to Address Food Insecurity and Promote Smoking Cessation Among Low-Income Adults.

Author

Kim-Mozeleski, Jin E., Castele, Madeline C., Nambiar, Pooja, Chagin, Kevin M., Pike Moore, Stephanie, Hardy, Patricia, Cook, Karen, and Sehgal, Ashwini R.

Subjects
SMOKING cessation, INCOME, T-test (Statistics), RESEARCH funding, FOOD security, PILOT projects, FISHER exact test, RANDOMIZED controlled trials, DESCRIPTIVE statistics, CHI-squared test, HEALTH promotion, MEDICAL needs assessment, HEALTH equity, PUBLIC welfare, DATA analysis software, POVERTY, ADULTS
Abstract

Many low-income adults who smoke also have unmet social needs, such as food insecurity, which can serve as a barrier to smoking cessation. We developed a novel intervention to jointly address smoking cessation and food insecurity and assessed its feasibility, acceptability, and preliminary outcomes. We enrolled participants who screened for food insecurity, reported smoking daily, and were ready to quit. All participants received 3 months of resources navigation from a community health worker through monthly telephone calls for referrals and check-ins for smoking cessation and food access resources. Participants randomized to the intervention group received an economic intervention equivalent to the cost of 1 week of groceries/month for 3 months. We randomized 55 participants who were smoking on average 13 cigarettes/day. The trial was feasible and acceptable based on 3-month retention rates (80%) and end-of-study qualitative feedback (91% would recommend the study to others). At 3 months, participants in the intervention versus control group reported a longer length of abstinence from smoking and had a higher proportion of serious quit attempts. Results from this pilot study suggest the importance of attending to social needs, particularly food insecurity, as a strategy to promote smoking cessation among low-income adults who smoke. [ABSTRACT FROM AUTHOR]

Published
2024
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2. PCs

Author

Kingdon, Sid, Poor, Alfred, and Hardy, Patricia

Published
1993

5. Location/Sites National = Locations/National

Author

Eyland, Cliff, Bean, Robert, Craig, David, Desnoyers, Monique, Lounder, Barbara, Quinn, Catherine, Merritt, David, McQuay, Steve, Needham, Wilma, Bernier, Jean-Jacques, Townsend, Martha, Boyer, Gilbert, Gougeon, Diane, McSherry, Fred, Wiens, Robert, Golden, Brad, Youds, Robert, Tivy, Sandra, Hardy, Patricia Ann, May, Walter, Spindler, Christoph, Will, John, Fischer, Barbara, Eyland, Cliff, Bean, Robert, Craig, David, Desnoyers, Monique, Lounder, Barbara, Quinn, Catherine, Merritt, David, McQuay, Steve, Needham, Wilma, Bernier, Jean-Jacques, Townsend, Martha, Boyer, Gilbert, Gougeon, Diane, McSherry, Fred, Wiens, Robert, Golden, Brad, Youds, Robert, Tivy, Sandra, Hardy, Patricia Ann, May, Walter, Spindler, Christoph, Will, John, and Fischer, Barbara

Abstract

This catalogue brings together descriptions of 31 public art projects presented in Halifax, Montréal, Toronto, Calgary and Victoria. Includes statements by some of the artists.

Published
1983

9. Silencing of amygdala circuits during sepsis prevents the development of anxiety-related behaviours

Author

Lena Bourhy, Aurélien Mazeraud, Luis H. A. Costa, Jarod Levy, Damien Rei, Estéban Hecquet, Ilana Gabanyi, Fernando A. Bozza, Fabrice Chrétien, Pierre-Marie Lledo, Tarek Sharshar, Gabriel Lepousez, Neuropathologie expérimentale / Experimental neuropathology, Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), Perception et Mémoire / Perception and Memory, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université Paris Cité (UPCité), GHU Paris Psychiatrie et Neurosciences, Universidade de São Paulo = University of São Paulo (USP), Microenvironnement et Immunité - Microenvironment and Immunity, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Fundação Oswaldo Cruz (FIOCRUZ), Réseau International des Instituts Pasteur (RIIP), D'Or Institute for Research and Education [Rio de Janeiro], Institut de psychiatrie et neurosciences de Paris (IPNP - U1266 Inserm), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), The Perception and Memory laboratory receives financial support from life insurance company ‘AG2R-La-Mondiale’. The project received some financial support from the Société de Réanimation de Langue Française (SRLF), the Conseil Régional d'Ile-de-France (DIM Malinf) and the Fondation pour la Recherche Médicale (FRM, FDM201806006452)., We thank David Hardy, Patricia Reis, Flora Magno, Tarik Hissem, Carine Moigneu, Alice Dupin and Noémi Dominique for their technical support. We thank Mathilde Bigot for her input on behavioural experiments, and all the members of ‘Perception and Memory’ and ‘Experimental Neuropathology’ laboratories for their advice and comments during this work. We are grateful to Alexandru A. Hennrich and Karl-Klaus Conzelmann (Max Von Pettenkofer Institute Virology and Gene Center, Medical Faculty, Ludwig-Maximilians-University Munich, Germany) for the generous gift of (EnvA)SAD-ΔG-mCherry virus. The authors wish also to thank the Genetically Encoded Neuronal Indicator and Effector (GENIE) Project and the Janelia Farm Research Campus of the Howard Hughes Medical Institute for sharing GCaMP6f constructs, as well as the neurologic exploration group in intensive care GENER., lepousez, gabriel, and Fundação Oswaldo Cruz / Oswaldo Cruz Foundation (FIOCRUZ)

Subjects
[SCCO.NEUR]Cognitive science/Neuroscience, Central Amygdaloid Nucleus, [SCCO.NEUR] Cognitive science/Neuroscience, cecal ligation and puncture, Fear, Anxiety, Anxiety Disorders, fear conditioning, neuroinflammation, neuro-immune interactions, Mice, Sepsis, Animals, Humans, optogenetic, Neurology (clinical)
Abstract

Sepsis is a life-threatening condition induced by a deregulated host response to severe infection. Post-sepsis syndrome includes long-term psychiatric disorders, such as persistent anxiety and post-traumatic stress disorder, whose neurobiological mechanisms remain unknown. Using a reference mouse model of sepsis, we showed that mice that recovered from sepsis further developed anxiety-related behaviours associated with an exaggerated fear memory. In the brain, sepsis induced an acute pathological activation of a specific neuronal population of the central nucleus of the amygdala, which projects to the ventral bed nucleus of the stria terminalis. Using viral-genetic circuit tracing and in vivo calcium imaging, we observed that sepsis induced persistent changes in the connectivity matrix and in the responsiveness of these central amygdala neurons projecting to the ventral bed nucleus of the stria terminalis. The transient and targeted silencing of this subpopulation only during the acute phase of sepsis with a viral pharmacogenetic approach, or with the anti-epileptic and neuroprotective drug levetiracetam, prevented the subsequent development of anxiety-related behaviours. Specific inhibition of brain anxiety and fear circuits during the sepsis acute phase constitutes a preventive approach to preclude the post-infection psychiatric outcomes.

Published
2022
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