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352 results on '"Hardwicke J"'

11. Investigation of the potential of polymer therapeutics in corneal re-epithelialisation

Author

Hardwicke, J., Song, B., Moseley, R., and Thomas, D.W.

Subjects
Corneal diseases -- Care and treatment, Corneal diseases -- Patient outcomes, Corneal diseases -- Research, Epidermal growth factor -- Usage, Epidermal growth factor -- Physiological aspects, Epidermal growth factor -- Research, Protein therapy -- Patient outcomes, Protein therapy -- Research, Health
Published
2010

29. Expanded version pedicled free-style perforator flaps in clinical practice: a need for a more comprehensive classification system.

Author

Kannan, Ruben Y. and Hardwicke, J.

Subjects
*PERFORATOR flaps (Surgery), *PLASTIC surgery
Abstract

Background: The evolution of the angiosome concept into the perforasome theory as we increasingly move towards the distal end of the microvascular tree for reconstructive options has allowed us to design ad hoc perforator flaps.Methods: In a retrospective sample of more than 60 pedicled perforator flaps over a 36-month period, a variety of defects in all regions of the body were reconstructed. Pre-operative planning was based on either Doppler vascular studies or CT angiography.Results: The overall complete flap survival rate was 89%, with a tip necrosis rate of 8.1% and a partial flap necrosis rate of 3.3%. The risk factors identified were smoking, nicotine patches, vasopressor use and pro-thrombotic states.Conclusions: It is feasible to perform the many variations of perforator flaps provided; the microsurgical anatomy of the area is well defined, aided by imaging studies as necessary. Risk stratification also needs to be taken into account when planning these flaps. Based on our results and observations, an alternative pedicled perforator flap classification is put forward.Level of Evidence: Level IV, therapeutic study. [ABSTRACT FROM AUTHOR]

Published
2018
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46. A novel architecture for active service management.

Author

Marshall, Ian W., Gharib, H., Hardwicke, J., Roadknight, C., Marshall, Ian W., Gharib, H., Hardwicke, J., and Roadknight, C.

Abstract

Future multiservice networks will be extremely large and complex. In this environment, active services will be needed to enable the rapid service evolution demanded by users. Active services also enable service management to be delegated to network users as a large set of independent small-scale management systems, thus minimising management costs. However, novel management solutions will be required to enable efficient multi-user management of the sites where the active services are run. We present an architecture for management of a network offering active services, which uses a combination of policies and adaptive algorithms to enable multi-user management of network based service components

Published
2001

47. A novel architecture for active service management

Author

Anerousis, N., Pavlou, G., Liotta, A., Marshall, Ian W., Gharib, H., Hardwicke, J., Roadknight, Chris, Anerousis, N., Pavlou, G., Liotta, A., Marshall, Ian W., Gharib, H., Hardwicke, J., and Roadknight, Chris

Abstract

Future multiservice networks will be extremely large and complex. In this environment, Active Services will be needed to enable the rapid service evolution demanded by users. Active services also enable service management to be delegated to network users as a large set of independent small-scale management systems, thus minimising management costs. However, novel management solutions will be required to enable efficient multi-user management of the sites where the active services are run. We present an architecture for management of a network offering active services, which uses a combination of policies and adaptive algorithms to enable multi-user management of network based service components.

Published
2001

49. Active management of multi-service networks.

Author

Marshall, I. W., Hardwicke, J., Gharib, H., Fisher, M., Mckee, P., Marshall, I. W., Hardwicke, J., Gharib, H., Fisher, M., and Mckee, P.

Abstract

Future multiservice networks will be extremely large and complex. Novel management solutions will be required to keep the management costs reasonable. Active networking enables management to be delegated to network users as a large set of independent small scale management systems. A novel architecture for an active network based management solution for multiservice networking is presented.

Published
2000

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