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246 results on '"Haplorhini metabolism"'

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1. Hepatic glucuronidation of tetrabromobisphenol A and tetrachlorobisphenol A: interspecies differences in humans and laboratory animals and responsible UDP-glucuronosyltransferase isoforms in humans.

2. Mechanistic Pharmacokinetics and Pharmacodynamics of GalNAc-siRNA: Translational Model Involving Competitive Receptor-Mediated Disposition and RISC-Dependent Gene Silencing Applied to Givosiran.

3. Evaluation of the risk of diarrhea induced by epidermal growth factor receptor tyrosine kinase inhibitors with cultured intestinal stem cells originated from crypts in humans and monkeys.

4. Human Embryonic Stem Cell-Derived Immature Midbrain Dopaminergic Neurons Transplanted in Parkinsonian Monkeys.

5. Laminar differences in functional oxygen metabolism in monkey visual cortex measured with calibrated fMRI.

6. Detection and identification of imperatorin metabolites in rat, dog, monkey, and human liver microsomes by ultra-high-performance liquid chromatography combined with high-resolution mass spectrometry and Compound Discoverer software.

7. Vegetable Oil-Peroxidation Product 'Hydroxynonenal' Causes Hepatocyte Injury and Steatosis via Hsp70.1 and BHMT Disorders in the Monkey Liver.

8. Determination of drug-to-antibody ratio of antibody-drug conjugate in biological samples using microflow-liquid chromatography/high-resolution mass spectrometry.

9. First-in-Human Evaluation of 18 F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B.

10. The accelerated evolution of human cytochrome c oxidase - Selection for reduced rate and proton pumping efficiency?

11. Time course of dorsolateral geniculate nucleus plasticity in adult monkeys with laser-induced retinal lesions.

12. SQSTM1-mediated clearance of cytoplasmic mutant TARDBP/TDP-43 in the monkey brain.

13. Towards a translational physiologically-based pharmacokinetic (PBPK) model for receptor-mediated transcytosis of anti-transferrin receptor monoclonal antibodies in the central nervous system.

14. Metabolism of anti-inflammatory OXE (oxoeicosanoid) receptor antagonists by nonhuman primates.

15. PET Imaging of VMAT2 with the Novel Radioligand [ 18 F]FE-DTBZ-d4 in Nonhuman Primates: Comparison with [ 11 C]DTBZ and [ 18 F]FE-DTBZ.

16. Scopolamine and MK-801 impair recognition memory in a new spontaneous object exploration task in monkeys.

17. The Vertical and Horizontal Pathways in the Monkey Retina Are Modulated by Typical and Atypical Cannabinoid Receptors.

18. GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys.

19. First progeria monkey model generated using base editor.

20. Imaging mitochondrial complex I activation during a vibrotactile stimulation: A PET study using [ 18 F]BCPP-EF in the conscious monkey brain.

21. Metabolism of desloratadine by chimeric TK-NOG mice transplanted with human hepatocytes.

22. Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys.

23. Anterior thalamic nucleus stimulation protects hippocampal neurons by activating autophagy in epileptic monkeys.

24. Hepatic expression of cytochrome P450 enzymes in non-human primate species.

25. Genetics of Cerebellar and Neocortical Expansion in Anthropoid Primates: A Comparative Approach.

26. Novel broad-spectrum and long-acting parenteral cephalosporins having an acyl cyanamide moiety at the C-3 terminal: Synthesis and structure-activity relationships.

27. Pharmacokinetics of Colistin Methansulphonate (CMS) and Colistin after CMS Nebulisation in Baboon Monkeys.

28. Comparison of minipig, dog, monkey and human drug metabolism and disposition.

29. Genetics. The battle for iron.

30. Escape from bacterial iron piracy through rapid evolution of transferrin.

31. CYP1A1 and CYP1B1-mediated biotransformation of the antitrypanosomal methamidoxime prodrug DB844 forms novel metabolites through intramolecular rearrangement.

33. TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys.

34. Monkey liver cytochrome P450 2C9 is involved in caffeine 7-N-demethylation to form theophylline.

35. Reassessment of the unique mode of binding between angiotensin II type 1 receptor and their blockers.

36. Elimination kinetics of perfluorohexanoic acid in humans and comparison with mouse, rat and monkey.

37. Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans.

38. High-throughput bioanalysis of bile acids and their conjugates using UHPLC coupled to HRMS.

39. Comparative analysis of the nucleus basalis of Meynert among primates.

41. Drug design tools--in silico, in vitro and in vivo ADME/PK prediction and interpretation: is PK in monkey an essential part of a good human PK prediction?

42. Computational studies of interactions between endocrine disrupting chemicals and androgen receptor of different vertebrate species.

43. Porcine induced pluripotent stem cells may bridge the gap between mouse and human iPS.

44. Characterization and antigenicity of the promising vaccine candidate Plasmodium vivax 34kDa rhoptry antigen (Pv34).

45. Synthesis and structure analysis of cyclodehydration product of piroxicam: a metabolite detected in dogs and monkeys.

46. Transplantation of embryonic stem cell-derived dopaminergic neurons in MPTP-treated monkeys.

47. Serum protein binding displacement: theoretical analysis using a hypothetical radiopharmaceutical and experimental analysis with 123I-N-isopropyl-p-iodoamphetamine.

48. Intergenic bidirectional promoter and cooperative regulation of the IIx and IIb MHC genes in fast skeletal muscle.

49. Selective decline of the metabolic competence of oversized synaptic mitochondria in the old monkey cerebellum.

50. Mammalian neo-oogenesis and expression of meiosis-specific protein SCP3 in adult human and monkey ovaries.

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