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622 results on '"Hanssen, Henner"'

1. Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop

Author

Chew, Emily Y., Burns, Stephen A., Abraham, Alison G., Bakhoum, Mathieu F., Beckman, Joshua A., Chui, Toco Y. P., Finger, Robert P., Frangi, Alejandro F., Gottesman, Rebecca F., Grant, Maria B., Hanssen, Henner, Lee, Cecilia S., Meyer, Michelle L., Rizzoni, Damiano, Rudnicka, Alicja R., Schuman, Joel S., Seidelmann, Sara B., Tang, W. H. Wilson, Adhikari, Bishow B., Danthi, Narasimhan, Hong, Yuling, Reid, Diane, Shen, Grace L., and Oh, Young S.

Published
2025
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6. Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation

Author

Kuchler, Timon, Günthner, Roman, Ribeiro, Andrea, Hausinger, Renate, Streese, Lukas, Wöhnl, Anna, Kesseler, Veronika, Negele, Johanna, Assali, Tarek, Carbajo-Lozoya, Javier, Lech, Maciej, Schneider, Heike, Adorjan, Kristina, Stubbe, Hans Christian, Hanssen, Henner, Kotilar, Konstantin, Haller, Bernhard, Heemann, Uwe, and Schmaderer, Christoph

Published
2023
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13. Effect of moderate to high intensity aerobic exercise on blood pressure in young adults: The TEPHRA open, two-arm, parallel superiority randomized clinical trial

Author

Williamson, Wilby, Lewandowski, Adam James, Huckstep, Odaro John, Lapidaire, Winok, Ooms, Alexander, Tan, Cheryl, Mohamed, Afifah, Alsharqi, Maryam, Bertagnolli, Mariane, Woodward, William, Dockerill, Cameron, McCourt, Annabelle, Kenworthy, Yvonne, Burchert, Holger, Doherty, Aiden, Newton, Julia, Hanssen, Henner, Cruickshank, John Kennedy, McManus, Richard, Holmes, Jane, Ji, Chen, Love, Sharon, Frangou, Elena, Everett, Colin, Hillsdon, Melvyn, Dawes, Helen, Foster, Charlie, and Leeson, Paul

Published
2022
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15. Correction: Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation

Author

Kuchler, Timon, Günthner, Roman, Ribeiro, Andrea, Hausinger, Renate, Streese, Lukas, Wöhnl, Anna, Kesseler, Veronika, Negele, Johanna, Assali, Tarek, Carbajo-Lozoya, Javier, Lech, Maciej, Schneider, Heike, Adorjan, Kristina, Stubbe, Hans Christian, Hanssen, Henner, Kotilar, Konstantin, Haller, Bernhard, Heemann, Uwe, and Schmaderer, Christoph

Published
2023
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21. Medium- to long-term health condition of patients post-COVID-19, exercise intolerance and potential mechanisms: A narrative review and perspective.

Author

Schwendinger, Fabian, Infanger, Denis, Maurer, Debbie J, Radtke, Thomas, Carrard, Justin, Kröpfl, Julia M, Emmenegger, Aglaia, Hanssen, Henner, Hauser, Christoph, Schwehr, Udo, Hirsch, Hans H, Ivanisevic, Julijana, Leuzinger, Karoline, Martinez, Aurélien E, Maurer, Marc, Sigrist, Thomas, Streese, Lukas, von Känel, Roland, Hinrichs, Timo, and Schmidt-Trucksäss, Arno

Published
2024
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22. Obesity and cardiovascular disease: an ESC clinical consensus statement.

Author

Koskinas, Konstantinos C, Craenenbroeck, Emeline M Van, Antoniades, Charalambos, Blüher, Matthias, Gorter, Thomas M, Hanssen, Henner, Marx, Nikolaus, McDonagh, Theresa A, Mingrone, Geltrude, Rosengren, Annika, Prescott, Eva B, and Group, the ESC Scientific Document

Subjects
CARDIOVASCULAR diseases risk factors, HEART valve diseases, CARDIAC arrest, CONSCIOUSNESS raising, CARDIOLOGICAL manifestations of general diseases, CARDIOVASCULAR diseases, HEART failure
Abstract

The global prevalence of obesity has more than doubled over the past four decades, currently affecting more than a billion individuals. Beyond its recognition as a high-risk condition that is causally linked to many chronic illnesses, obesity has been declared a disease per se that results in impaired quality of life and reduced life expectancy. Notably, two-thirds of obesity-related excess mortality is attributable to cardiovascular disease. Despite the increasingly appreciated link between obesity and a broad range of cardiovascular disease manifestations including atherosclerotic disease, heart failure, thromboembolic disease, arrhythmias, and sudden cardiac death, obesity has been underrecognized and sub-optimally addressed compared with other modifiable cardiovascular risk factors. In the view of major repercussions of the obesity epidemic on public health, attention has focused on population-based and personalized approaches to prevent excess weight gain and maintain a healthy body weight from early childhood and throughout adult life, as well as on comprehensive weight loss interventions for persons with established obesity. This clinical consensus statement by the European Society of Cardiology discusses current evidence on the epidemiology and aetiology of obesity; the interplay between obesity, cardiovascular risk factors and cardiac conditions; the clinical management of patients with cardiac disease and obesity; and weight loss strategies including lifestyle changes, interventional procedures, and anti-obesity medications with particular focus on their impact on cardiometabolic risk and cardiac outcomes. The document aims to raise awareness on obesity as a major risk factor and provide guidance for implementing evidence-based practices for its prevention and optimal management within the context of primary and secondary cardiovascular disease prevention. [ABSTRACT FROM AUTHOR]

Published
2024
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23. 2024 ESC Guidelines for the management of elevated blood pressure and hypertension: Developed by the task force on the management of elevated blood pressure and hypertension of the European Society of Cardiology (ESC) and endorsed by the European Society of Endocrinology (ESE) and the European Stroke Organisation (ESO)

Author

McEvoy, John William, McCarthy, Cian P, Bruno, Rosa Maria, Brouwers, Sofie, Canavan, Michelle D, Ceconi, Claudio, Christodorescu, Ruxandra Maria, Daskalopoulou, Stella S, Ferro, Charles J, Gerdts, Eva, Hanssen, Henner, Harris, Julie, Lauder, Lucas, McManus, Richard J, Molloy, Gerard J, Rahimi, Kazem, Regitz-Zagrosek, Vera, Rossi, Gian Paolo, Sandset, Else Charlotte, and Scheenaerts, Bart

Subjects
HEART failure, BRAIN natriuretic factor, DASH diet, FRAIL elderly, HYPERTENSIVE crisis, AMBULATORY blood pressure monitoring
Abstract

The document titled "2024 ESC Guidelines for the management of elevated blood pressure and hypertension" provides comprehensive guidelines for the management of high blood pressure and hypertension. It covers various topics such as the pathophysiology and clinical consequences of elevated blood pressure, methods for measuring blood pressure, risk assessment for cardiovascular disease, diagnosing hypertension and investigating underlying causes, prevention and treatment strategies, managing specific patient groups or circumstances, acute and short-term blood pressure management, and patient-centered care. The guidelines aim to provide evidence-based recommendations for healthcare professionals in order to improve the management and prevention of hypertension and its associated complications. [Extracted from the article]

Published
2024
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24. The role of exercise training on cardiovascular risk factors and heart disease in patients with chronic kidney disease G3–G5 and G5D: a Clinical Consensus Statement of the European Association of Preventive Cardiology of the ESC and the European Association of Rehabilitation in Chronic Kidney Disease

Author

Kouidi, Evangelia, Hanssen, Henner, Anding-Rost, Kirsten, Cupisti, Adamasco, Deligiannis, Asterios, Grupp, Clemens, Koufaki, Pelagia, Leeson, Paul, Segura-Orti, Eva, Craenenbroeck, Amaryllis Van, Craenenbroeck, Emeline Van, Clyne, Naomi, and Halle, Martin

Published
2024
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26. Effect of an eight-week high-intensity interval training programme on circulating sphingolipid levels in middle-aged adults at elevated cardiometabolic risk (SphingoFIT)—Protocol for a randomised controlled exercise trial

Author

Carrard, Justin, primary, Hofer, Manuel, additional, Prechtl, Luisa, additional, Fleischlin, Eva, additional, Huber, Manuel, additional, Gallart-Ayala, Hector, additional, Teav, Tony, additional, Infanger, Denis, additional, Höchsmann, Christoph, additional, Koehler, Karsten, additional, Hinrichs, Timo, additional, Hanssen, Henner, additional, Ivanisevic, Julijana, additional, and Schmidt-Trucksäss, Arno, additional

Published
2024
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27. The role of exercise training on cardiovascular risk factors and heart disease in patients with chronic kidney disease G3-G5 and G5D: A Clinical Consensus Statement of the European Association of Preventive Cardiology (EAPC) of the ESC and the European Association of Rehabilitation in Chronic Kidney Disease (EURORECKD)

Author

Kouidi, Evangelia, primary, Hanssen, Henner, additional, Anding-Rost, Kirsten, additional, Cupisti, Adamasco, additional, Deligiannis, Asterios, additional, Grupp, Clemens, additional, Koufaki, Pelagia, additional, Leeson, Paul, additional, Segura-Orti, Eva, additional, Van Craenenbroeck, Amaryllis, additional, Van Craenenbroeck, Emeline, additional, Clyne, Naomi, additional, and Martin, Halle, additional

Published
2024
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32. Subcutaneous advanced glycation end products, cardiovascular risk factors and vascular health during childhood development in a Swiss population.

Author

Hauser, Christoph, Lona, Giulia, Köchli, Sabrina, Streese, Lukas, Infanger, Denis, Faude, Oliver, and Hanssen, Henner

Subjects
ADVANCED glycation end-products, PULSE wave analysis, CHILD development, CARDIOVASCULAR diseases risk factors, BODY mass index
Abstract

Background: Skin-derived advanced glycation end products (sAGEs) have been associated with cardiovascular (CV) risk and mortality in adults. We hypothesize that cardiorespiratory fitness (CRF), body mass index (BMI) and vascular health are associated with development of sAGEs during childhood. Methods: In our prospective cohort study, 1171 children aged 6-8 years were screened for sAGEs, BMI, retinal arteriolar diameters (CRAE) and pulse wave velocity (PWV), using standardized procedures. To determine CRF a 20 m shuttle run was performed. After four 4 years, all parameters were assessed in 675 children using the same protocols. Results: Higher initial CRF levels were significantly associated with lower sAGEs (β [95 CI] -0.02 [-0.03 to -0.002] au, p = 0.022) levels at follow-up, although they showed a greater change from baseline to follow-up (β [95 CI] 0.02 [0.002 to 0.03] au, p = 0.027). Moreover, individuals with higher sAGEs at baseline showed narrower CRAE (β [95% CI] -5.42 [-8.76 to -2.08] μm, p = 0.001) at follow-up and showed a greater change in CRAE (β [95% CI] -3.99 [-7.03 to -0.96] μm, p = 0.010) from baseline to follow-up. Conclusion: Exercise and higher CRF may help mitigate the formation of AGEs during childhood, thereby reducing the risk for development of CV disease associated with AGEs-induced damage. Preventive strategies may need to target CRF early in life to achieve improvement of CV risk factors and may counteract the development of CV disease later in life. [ABSTRACT FROM AUTHOR]

Published
2024
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34. Spezielle Prävention

Author

Schwab, Karl Otfried, Doerfer, Jürgen, Hanssen, Henner, Stier, Bernhard, editor, Weissenrieder, Nikolaus, editor, and Schwab, Karl Otfried, editor

Published
2018
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47. Effects of a 5-week intake of erythritol and xylitol on vascular function, abdominal fat and glucose tolerance in humans with obesity: a pilot trial

Author

Bordier, Valentine, primary, Teysseire, Fabienne, additional, Drewe, Jürgen, additional, Madörin, Philipp, additional, Bieri, Oliver, additional, Schmidt-Trucksäss, Arno, additional, Hanssen, Henner, additional, Beglinger, Christoph, additional, Meyer-Gerspach, Anne Christin, additional, and Wölnerhanssen, Bettina K, additional

Published
2023
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49. High-intensity interval training in patients with glaucoma (HIT-GLAUCOMA): protocol for a multicenter randomized controlled exercise trial.

Author

Van Eijgen, Jan, Schuhmann, Valentin, Fingerroos, Emma-Liina, Renier, Marie, Burchert, Holger, Kröpfl, Julia Maria, Van Craenenbroeck, Amaryllis, Cornelissen, Véronique, Gugleta, Konstantin, Stalmans, Ingeborg, and Hanssen, Henner

Subjects
RANDOMIZED controlled trials, HIGH-intensity interval training, OPEN-angle glaucoma, INTERVAL training, GLAUCOMA, EXERCISE therapy, NEURAL circuitry, OPTIC nerve injuries
Abstract

Background: Glaucoma stands as a prominent global cause of irreversible blindness and the primary treatment approach involves reducing intraocular pressure (IOP). However, around one-third of patients exhibit disease progression despite effective IOP reduction. Microvascular endothelial function, chronic inflammation, and oxidative stress are known to affect retinal neuronal networks and have been associated with disease severity and progression. Exercise training has the potential to counteract these mechanisms as add-on treatment to usual care. Aims: The HIT-GLAUCOMA study will investigate the effects of a 6-month highintensity interval training (HIIT) on intermediate endpoints such as local retinal microvascular and systemic large artery function, inflammation, and oxidative stress as well as clinical endpoints such as visual field indices, optic nerve rim assessment, retinal nerve fiber layer thickness, IOP, number of eye drops, visionrelated quality of life and ocular surface disease symptomatology. Methods: The study is a multi-center randomized controlled clinical trial in patients with both normal tension and high-tension primary open angle glaucoma. Across two study centers, 128 patients will be enrolled and randomized on a 1:1 basis into an exercise intervention group and a usual care control group. The primary microvascular endpoints are retinal arteriolar and venular flicker light-induced dilation at 6 months. The primary endpoint in the systemic circulation is brachial artery flow-mediated dilation at 6 months. Anticipated results: We hypothesize that exercise therapy will improve retinal microvascular function and thus ocular blood flow in patients with glaucoma. As clinical outcomes, we will investigate the effect of exercise on visual field indices, optic nerve rim assessment, retinal nerve fiber layer thickness, IOP, number of eye drops, vision-related quality of life and ocular surface disease symptomatology. Discussion: HIT-GLAUCOMA is a blueprint trial design to study the effect of exercise training on neurodegenerative and cardiovascular diseases. Importantly, patients are also expected to benefit from improvements in general health and cardiovascular co-morbidities. If proven effective, exercise may offer a new add-on treatment strategy to slow glaucoma progression. [ABSTRACT FROM AUTHOR]

Published
2024
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