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1. POS0765 MOVEMENT BEHAVIOR AMONG ADOLESCENTS WITH JUVENILE IDIOPATHIC ARTHRITIS: RESULTS FROM THE ACTIMON STUDY

Author

Milatz, F., primary, Klotsche, J., additional, Kallinich, T., additional, Trauzeddel, R., additional, Windschall, D., additional, Hansmann, S., additional, Haas, J. P., additional, Baumeister, N., additional, Klaas, M., additional, Girschick, H., additional, Peitz-Kornbrust, J., additional, Burchartz, A., additional, and Minden, K., additional

Published
2024
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3. Entwicklung und psychometrische Validierung eines Selbsterhebungs-Instrumentes zur übergreifenden Erfassung von Kompetenzen, ungedeckten Bedarfen und der Zufriedenheit im Transitionsprozess

Author

Haney, H, Niewerth, M, Klotsche, J, Schalm, S, Hoff, P, Tatsis, S, Foeldvari, I, Kötter, I, Seipelt, E, Erbis, G, Hansmann, S, Reiser, C, Saur, SJ, Schua, S, Hardt, S, Ratanski, M, Maier, A, Minden, K, Haney, H, Niewerth, M, Klotsche, J, Schalm, S, Hoff, P, Tatsis, S, Foeldvari, I, Kötter, I, Seipelt, E, Erbis, G, Hansmann, S, Reiser, C, Saur, SJ, Schua, S, Hardt, S, Ratanski, M, Maier, A, and Minden, K

Published
2023

4. 24-Monats-Daten zu Wirksamkeit und Sicherheit von Tocilizumab im Vergleich zu TNF Inhibitoren bei polyartikulärer juveniler idiopathischer Arthritis

Author

Horneff, G, Zimmer, A, Hufnagel, M, Hospach, A, Weller-Heinemann, F, Kümmerle-Deschner, JB, Hansmann, S, Fasshauer, M, Minden, K, Foeldvari, I, Windschall, D, Föll, D, Oommen, PT, Klein, A, Horneff, G, Zimmer, A, Hufnagel, M, Hospach, A, Weller-Heinemann, F, Kümmerle-Deschner, JB, Hansmann, S, Fasshauer, M, Minden, K, Foeldvari, I, Windschall, D, Föll, D, Oommen, PT, and Klein, A

Published
2023

6. Versorgungssituation junger Rheumatiker mit chronischen Arthritiden - eine bevölkerungsbezogene Umfrage

Author

Minden, K, Marschall, U, Liedmann, I, Niewerth, M, Reiser, C, Tatsis, S, Foeldvari, I, Erbis, G, Seipelt, E, Hansmann, S, Maier, A, Ratanski, M, Schua, S, Brunner, J, Mrusek, S, Kötter, I, Schalm, S, Minden, K, Marschall, U, Liedmann, I, Niewerth, M, Reiser, C, Tatsis, S, Foeldvari, I, Erbis, G, Seipelt, E, Hansmann, S, Maier, A, Ratanski, M, Schua, S, Brunner, J, Mrusek, S, Kötter, I, and Schalm, S

Published
2023

9. Objektive Erfassung körperlicher Aktivität und sitzenden Verhaltens bei Jugendlichen mit juveniler idiopathischer Arthritis (JIA) - erste Ergebnisse aus ActiMON

Author

Milatz, F, Trauzeddel, R, Kallinich, T, Klaas, M, Girschick, HJ, Hansmann, S, Horneff, G, Windschall, D, Haas, JP, Baumeister, N, Niewerth, M, Minden, K, Milatz, F, Trauzeddel, R, Kallinich, T, Klaas, M, Girschick, HJ, Hansmann, S, Horneff, G, Windschall, D, Haas, JP, Baumeister, N, Niewerth, M, and Minden, K

Published
2022

10. Wirksamkeit und Sicherheit von IL-6-Inhibition (Tocilizumab) im Vergleich zu TNF-Inhibition bei polyartikulärer juveniler idiopathischer Arthritis: Ergebnisse aus dem BIKER-Register

Author

Klein, A, Zimmer, A, Hospach, A, Weller-Heinemann, F, Hansmann, S, Kuemmerle Deschner, J, Fasshauer, M, Minden, K, Foeldvari, I, Rietschel, C, Windschall, D, Ralf, T, Hufnagel, M, Foell, D, Berende, R, Oommen, P, Böschow, G, Dressler, F, Horneff, G, Klein, A, Zimmer, A, Hospach, A, Weller-Heinemann, F, Hansmann, S, Kuemmerle Deschner, J, Fasshauer, M, Minden, K, Foeldvari, I, Rietschel, C, Windschall, D, Ralf, T, Hufnagel, M, Foell, D, Berende, R, Oommen, P, Böschow, G, Dressler, F, and Horneff, G

Published
2022

11. Gesundheitsbezogene Transitionskompetenz bei Jugendlichen und jungen Erwachsenen mit juveniler idiopathischer Arthritis (JIA)

Author

Niewerth, M, Minden, K, Schalm, S, Foeldvari, I, Dollinger, S, Horneff, G, Windschall, D, Kallinich, T, Dressler, F, Weller-Heinemann, F, Berendes, R, Hospach, T, Hufnagel, M, Haller, M, Hansmann, S, Klotsche, J, Niewerth, M, Minden, K, Schalm, S, Foeldvari, I, Dollinger, S, Horneff, G, Windschall, D, Kallinich, T, Dressler, F, Weller-Heinemann, F, Berendes, R, Hospach, T, Hufnagel, M, Haller, M, Hansmann, S, and Klotsche, J

Published
2022

12. TRANSITION COMPETENCE IN YOUNG PEOPLE WITH JUVENILE IDIOPATHIC ARTHRITIS HAS IMPROVED OVER TIME

Author

Minden, K., Niewerth, M., Schalm, S., Foeldvari, I., Haas, J. P., Horneff, G., Windschall, D., Kallinich, T., Dressler, F., Weller-Heinemann, F., Berendes, R., Hospach, T., Hufnagel, M., Haller, M., Hansmann, S., Klotsche, J., Minden, K., Niewerth, M., Schalm, S., Foeldvari, I., Haas, J. P., Horneff, G., Windschall, D., Kallinich, T., Dressler, F., Weller-Heinemann, F., Berendes, R., Hospach, T., Hufnagel, M., Haller, M., Hansmann, S., and Klotsche, J.

Published
2022

13. EFFECTIVENESS AND SAFETY OF IL-6 INHIBITION (TOCILIZUMAB) VERSUS TUMOUR NECROSIS FACTOR INHIBITION IN POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS: RESULTS FROM THE OBSERVATIONAL BIKER STUDY

Author

Klein, A., Zimmer, A., Hospach, T., Weller-Heinemann, F., Hansmann, S., Kuemmerle-Deschner, J., Fasshauer, M., Minden, K., Foeldvari, I., Rietschel, C., Windschall, D., Trauzeddel, R., Hufnagel, M., Foell, D., Berendes, R., Boeschow, G., Oommen, P., Dressler, F., Horneff, G., Klein, A., Zimmer, A., Hospach, T., Weller-Heinemann, F., Hansmann, S., Kuemmerle-Deschner, J., Fasshauer, M., Minden, K., Foeldvari, I., Rietschel, C., Windschall, D., Trauzeddel, R., Hufnagel, M., Foell, D., Berendes, R., Boeschow, G., Oommen, P., Dressler, F., and Horneff, G.

Published
2022

14. ACCELEROMETER-ASSESSED DAILY PHYSICAL ACTIVITY AND SEDENTARY BEHAVIOUR IN ADOLESCENTS WITH JUVENILE IDIOPATHIC ARTHRITIS (JIA) - FIRST RESULTS FROM THE GERMAN ACTIMON STUDY

Author

Milatz, F., Trauzeddel, R., Kallinich, T., Klaas, M., Girschick, H., Hansmann, S., Horneff, G., Windschall, D., Haas, J. P., Baumeister, N., Niewerth, M., Minden, K., Milatz, F., Trauzeddel, R., Kallinich, T., Klaas, M., Girschick, H., Hansmann, S., Horneff, G., Windschall, D., Haas, J. P., Baumeister, N., Niewerth, M., and Minden, K.

Published
2022

15. POS0338 TRANSITION COMPETENCE IN YOUNG PEOPLE WITH JUVENILE IDIOPATHIC ARTHRITIS HAS IMPROVED OVER TIME

Author

Minden, K., primary, Niewerth, M., additional, Schalm, S., additional, Foeldvari, I., additional, Haas, J. P., additional, Horneff, G., additional, Windschall, D., additional, Kallinich, T., additional, Dressler, F., additional, Weller-Heinemann, F., additional, Berendes, R., additional, Hospach, T., additional, Hufnagel, M., additional, Haller, M., additional, Hansmann, S., additional, and Klotsche, J., additional

Published
2022
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16. POS1323 ACCELEROMETER-ASSESSED DAILY PHYSICAL ACTIVITY AND SEDENTARY BEHAVIOUR IN ADOLESCENTS WITH JUVENILE IDIOPATHIC ARTHRITIS (JIA) – FIRST RESULTS FROM THE GERMAN ActiMON STUDY

Author

Milatz, F., primary, Trauzeddel, R., additional, Kallinich, T., additional, Klaas, M., additional, Girschick, H., additional, Hansmann, S., additional, Horneff, G., additional, Windschall, D., additional, Haas, J. P., additional, Baumeister, N., additional, Niewerth, M., additional, and Minden, K., additional

Published
2022
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17. OP0217 EFFECTIVENESS AND SAFETY OF IL-6 INHIBITION (TOCILIZUMAB) VERSUS TUMOUR NECROSIS FACTOR INHIBITION IN POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS: RESULTS FROM THE OBSERVATIONAL BIKER STUDY

Author

Klein, A., primary, Zimmer, A., additional, Hospach, T., additional, Weller-Heinemann, F., additional, Hansmann, S., additional, Kuemmerle-Deschner, J., additional, Fasshauer, M., additional, Minden, K., additional, Foeldvari, I., additional, Rietschel, C., additional, Windschall, D., additional, Trauzeddel, R., additional, Hufnagel, M., additional, Foell, D., additional, Berendes, R., additional, Boeschow, G., additional, Oommen, P., additional, Dressler, F., additional, and Horneff, G., additional

Published
2022
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18. Integration of advanced methods and models to study drug absorption and related processes: An UNGAP perspective

Author

Wilson, C.G. Aarons, L. Augustijns, P. Brouwers, J. Darwich, A.S. De Waal, T. Garbacz, G. Hansmann, S. Hoc, D. Ivanova, A. Koziolek, M. Reppas, C. Schick, P. Vertzoni, M. García-Horsman, J.A.

Abstract

This collection of contributions from the European Network on Understanding Gastrointestinal Absorption-related Processes (UNGAP) community assembly aims to provide information on some of the current and newer methods employed to study the behaviour of medicines. It is the product of interactions in the immediate pre-Covid period when UNGAP members were able to meet and set up workshops and to discuss progress across the disciplines. UNGAP activities are divided into work packages that cover special treatment populations, absorption processes in different regions of the gut, the development of advanced formulations and the integration of food and pharmaceutical scientists in the food-drug interface. This involves both new and established technical approaches in which we have attempted to define best practice and highlight areas where further research is needed. Over the last months we have been able to reflect on some of the key innovative approaches which we were tasked with mapping, including theoretical, in silico, in vitro, in vivo and ex vivo, preclinical and clinical approaches. This is the product of some of us in a snapshot of where UNGAP has travelled and what aspects of innovative technologies are important. It is not a comprehensive review of all methods used in research to study drug dissolution and absorption, but provides an ample panorama of current and advanced methods generally and potentially useful in this area. This collection starts from a consideration of advances in a priori approaches: an understanding of the molecular properties of the compound to predict biological characteristics relevant to absorption. The next four sections discuss a major activity in the UNGAP initiative, the pursuit of more representative conditions to study lumenal dissolution of drug formulations developed independently by academic teams. They are important because they illustrate examples of in vitro simulation systems that have begun to provide a useful understanding of formulation behaviour in the upper GI tract for industry. The Leuven team highlights the importance of the physiology of the digestive tract, as they describe the relevance of gastric and intestinal fluids on the behaviour of drugs along the tract. This provides the introduction to microdosing as an early tool to study drug disposition. Microdosing in oncology is starting to use gamma-emitting tracers, which provides a link through SPECT to the next section on nuclear medicine. The last two papers link the modelling approaches used by the pharmaceutical industry, in silico to Pop-PK linking to Darwich and Aarons, who provide discussion on pharmacometric modelling, completing the loop of molecule to man. © 2021 The Authors

Published
2022

20. Consensus classification criteria for paediatric Behçetʼs disease from a prospective observational cohort: PEDBD

Author

Koné-Paut, Isabelle, Shahram, Fahrad, Darce-Bello, Martha, Cantarini, Luca, Cimaz, Rolando, Gattorno, Marco, Anton, Jordi, Hofer, Michael, Chkirate, Bouchra, Bouayed, Kenza, Tugal-Tutkun, Ilknur, Kuemmerle-Deschner, Jasmin, Agostini, Hélène, Federici, Sylvia, Arnoux, Armelle, Piedvache, Celine, Ozen, Seza, Ozdogan, H, Gul, A, Koné-Paut, I, Retornaz, K, Jurquet, AL, Touitou, I, Barat, M, Quartier, P, Faye, A, Despert, V, Pajot, C, Lemelle, I, Boussioux, JL, Tran, TA, Mikou, N, Benamour, S, Bono, W, Kasapcopur, O, Ozdogan, H, Gul, A, Al Mayouf, S, Khubchandani, R, Khalil, S Assad, Davatchi, F, Hansmann, S, Nielsen, S, Benzaoui, A, Tir, K, Ruperto, N, Naseli, A, and Lepore, L

Published
2016
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21. POS0077 PHYSICAL ACTIVITY AND SPORT PARTICIPATION: A COMPARISON BETWEEN CHILDREN AND ADOLESCENTS WITH JUVENILE IDIOPATHIC ARTHRITIS (JIA) AND THE GERMAN GENERAL POPULATION

Author

Milatz, F., primary, Niewerth, M., additional, Klotsche, J., additional, Hörstermann, J., additional, Hansmann, S., additional, Kallinich, T., additional, Rietschel, C., additional, Trauzeddel, R., additional, Peitz, J., additional, Hartmann, M., additional, Girschick, H., additional, and Minden, K., additional

Published
2021
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22. POS1321 MENTAL HEALTH SCREENING IN PATIENTS WITH JUVENILE IDIOPATHIC ARTHRITIS

Author

Eulert, S., primary, Niewerth, M., additional, Hörstermann, J., additional, Sengler, C., additional, Windschall, D., additional, Kallinich, T., additional, Grulich-Henn, J., additional, Weller-Heinemann, F., additional, Foeldvari, I., additional, Hansmann, S., additional, Baumeister, H., additional, Holl, R., additional, Staab, D., additional, and Minden, K., additional

Published
2021
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24. Exercise and sport in chronic diseases

Author

Hartmann, M., primary, Meyer, M., additional, Brudy, L., additional, Oberhoffer-Fritz, R., additional, Böhm, R., additional, Hebestreit, H., additional, and Hansmann, S., additional

Published
2020
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25. SAT0502 LONG-TERM OBSERVATIONAL SAFETY SURVEILLANCE OF GOLIMUMAB TREATMENT FOR POLYARTICULAR JUVENILE IDIOPATHIC ARTHIRTIS—AN INTERIM ANALYSIS

Author

Horneff, G., primary, Zimmer, A., additional, Minden, K., additional, Hospach, T., additional, Weller-Heinemann, F., additional, Hansmann, S., additional, Kuemmerle-Deschner, J., additional, Fasshauer, M., additional, Hofmann, N., additional, Koessel, H., additional, Foeldvari, I., additional, Mrusek, S., additional, Windschall, D., additional, Onken, N., additional, Hufnagel, M., additional, Foell, D., additional, Brueck, N., additional, Oommen, P., additional, Dressler, F., additional, Helling-Bakki, A., additional, and Klein, A., additional

Published
2020
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26. SAT0490 MATCHED CONTROLLED SURVEILLANCE OF TOCILIZUMAB TREATMENT FOR POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS–AN INTERIM ANALYSIS

Author

Klein, A., primary, Hospach, T., additional, Weller-Heinemann, F., additional, Hansmann, S., additional, Kuemmerle-Deschner, J., additional, Fasshauer, M., additional, Minden, K., additional, Foeldvari, I., additional, Rietschel, C., additional, Schwarz, T., additional, Trauzeddel, R., additional, Hufnagel, M., additional, Foell, D., additional, Berendes, R., additional, Boeschow, G., additional, Oommen, P., additional, Dressler, F., additional, Helling-Bakki, A., additional, and Horneff, G., additional

Published
2020
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29. Tocilizumab-Behandlung im Vergleich zur Behandlung mit TNF-Inhibitoren bei polyartikulärer juveniler idiopathischer Arthritis mit - Daten aus dem BIKER Register

Author

Klein, A, Minden, K, Hufnagel, M, Trauzeddel, R, Ganser, G, Weller-Heinemann, F, Rietschel, C, Hospach, A, Foeldvari, I, Kümmerle-Deschner, J, Föll, D, Hansmann, S, Conzelmann, D, Borte, M, Oommen, PT, Thon, A, Böschow, G, Berendes, R, Horneff, G, Klein, A, Minden, K, Hufnagel, M, Trauzeddel, R, Ganser, G, Weller-Heinemann, F, Rietschel, C, Hospach, A, Foeldvari, I, Kümmerle-Deschner, J, Föll, D, Hansmann, S, Conzelmann, D, Borte, M, Oommen, PT, Thon, A, Böschow, G, Berendes, R, and Horneff, G

Published
2019

31. Seltene Erkrankung mit Sakroiliitis

Author

Welzel, T, Reicherter, K, Schlipf, S, Hansmann, S, Hospach, A, Tsiflikas, I, Liu, X, Benseler, S, Weber, AN, Kümmerle-Deschner, JB, Welzel, T, Reicherter, K, Schlipf, S, Hansmann, S, Hospach, A, Tsiflikas, I, Liu, X, Benseler, S, Weber, AN, and Kümmerle-Deschner, JB

Published
2019

32. Langzeitüberwachung der Sicherheit von Biologikatherapien bei systemischer juveniler idiopathischer Arthritis

Author

Klein, A, Klotsche, J, Dressler, F, Trauzeddel, R, Minden, K, Hospach, A, Rietschel, C, Rühlmann, M, Weller-Heinemann, F, Lilienthal, E, Sailer-Höck, M, Hufnagel, M, Urban, A, Ganser, G, Emminger, W, Hügle, B, Hansmann, S, Horneff, G, Klein, A, Klotsche, J, Dressler, F, Trauzeddel, R, Minden, K, Hospach, A, Rietschel, C, Rühlmann, M, Weller-Heinemann, F, Lilienthal, E, Sailer-Höck, M, Hufnagel, M, Urban, A, Ganser, G, Emminger, W, Hügle, B, Hansmann, S, and Horneff, G

Published
2019

36. Static and dynamic properties of InGaAsP-InP distributed feedback lasers - a detailed comparison between experiment and theory

Author

Hansmann, S., Walter, H., Hillmer, H., and Burkhard, H.

Subjects
Semiconductor lasers -- Research, Feedback (Electronics) -- Research, Business, Computers, Electronics, Electronics and electrical industries
Abstract

A comparative study of the theoretical and experimental studies of phase shifted INGaAsP-InP distributed feedback lasers helps examine the dynamic and static properties of the lasers. Theoretical model studies include a rate equation analysis and a transfer matrix method to explain longitudinal mode spatial hole burning effects while experimental studies include estimates of current-induced mode wavelength changes, small signal amplitude modulation, side mode suppression ratio and responses to signal modulation. Theoretical and experimental results are correlated.

Published
1994

37. Study of wavelength shift in InGaAs/InAlGaAs QW DFB lasers based on laser parameters from a comparison of experiment and theory

Author

Hillmer, Hartmut, Hansmann, S., Burkhard, Herbert, Walter, Herbert, Krost, Alois, and Bimberg, Dieter

Subjects
Semiconductor lasers -- Research, Business, Computers, Electronics, Electronics and electrical industries
Abstract

Comparative examination of theoretical and experimental results on InGaAs/InAlGaAs quantum well distributed feedback (DFB) lasers using a transfer matrix method yields a set of physical DFB laser parameters that help elucidate the wavelength shift in the laser spectrum. The parameter set indicates that the influence of end facet phases on wavelength shift accounts for the end facet phase-dependent behavior of wavelength tunability. The shift value differs between a factor and three and is essential for tunable multisection DFB lasers.

Published
1994

38. Theoretical and experimental study of inhomogeneously pumped distributed feedback lasers

Author

Hansmann, S., Hillmer, H., Janning, H., and Burkhard, H.

Subjects
Lasers -- Research, Physics
Abstract

The theoretical and experimental investigation of the inhomogeneously pumped index-coupled distributed feedback (OFB) laser structures shows that enhanced stability of the Bragg mode can be achieved. The optimized device structure, designed by the use of a transfer matrix, suppresses the longitudinal sidemodes by concentrating the injection current in the region close to phase shift position. High yield monomode lasers together with an easy fabrication technique were achieved with this method, without the use of end fact antireflection coating.

Published
1993

41. Performance of the autoinflammatory disease damage index (ADDI) in patients with CAPS, TRAPS, HIDS and FMF

Author

Hansmann, S and Kümmerle-Deschner, J

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Background: Autoinflammatory diseases (AID) cause inflammation in multiple organ systems. To quantify organ damage caused by inflammation, the autoinflammatory disease damage index (ADDI) has been developed [ref:1]. In this pilot study, the performance of the ADDI score has been tested in [for full text, please go to the a.m. URL], 45. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 31. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 27. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2017
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42. Recommendations for collaborative paediatric research including biobanking in Europe – A Single HUB and Access Point for Paediatric Rheumatology in Europe (SHARE) Initiative

Author

Hansmann, S, Kümmerle-Deschner, J, Wulffraat, N, and Benseler, S

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Background: Innovative research in childhood rare diseases mandates international collaborations. However, researchers struggle with the dramatic regulatory heterogeneity. An EU-wide framework enabling collaborative paediatric research is missing. The aims of the study were to systematically review [for full text, please go to the a.m. URL], 45. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 31. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 27. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2017
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49. Unmet psychosocial needs in CAPS

Author

Erbis, G, Benseler, S, Hansmann, S, Iris, H, Sergiichuk, T, Kümmerle-Deschner, J, Erbis, G, Benseler, S, Hansmann, S, Iris, H, Sergiichuk, T, and Kümmerle-Deschner, J

Published
2015

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