1,481 results on '"Hansen, P. M."'
Search Results
2. The cold Jupiter eccentricity distribution is consistent with EKL driven by stellar companions
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Weldon, Grant C., Naoz, Smadar, and Hansen, Bradley M. S.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
The large eccentricities of cold Jupiters and the existence of hot Jupiters have long challenged theories of planet formation. A proposed solution to both of these puzzles is high-eccentricity migration, in which an initially cold Jupiter is excited to high eccentricities before being tidally circularized. Secular perturbations from an inclined stellar companion are a potential source of eccentricity oscillations, a phenomenon known as the Eccentric Kozai-Lidov (EKL) mechanism. Previous studies have found that the cold Jupiter eccentricity distribution produced by EKL is inconsistent with observations. However, these studies assumed all planets start on circular orbits. Here, we revisit this question, considering that an initial period of planet-planet scattering on $\sim$Myr timescales likely places planets on slightly eccentric orbits before being modulated by EKL on $\sim$Myr-Gyr timescales. Small initial eccentricities can have a dramatic effect by enabling EKL to act at lower inclinations. We numerically integrate the secular hierarchical three-body equations of motion, including general relativity and tides, for populations of cold giant planets in stellar binaries with varied initial eccentricity distributions. For populations with modest initial mean eccentricities, the simulated eccentricity distribution produced by EKL is statistically consistent with the observed eccentricities of cold single-planet systems. The lower eccentricities in a multi-planet control sample suggest that planetary companions quench stellar EKL. We show that scattering alone is unlikely to reproduce the present-day eccentricity distribution. We also show that the anisotropic inclination distribution produced by EKL may lead radial velocity measurements to underestimate giant planet masses., Comment: Submitted to ApJL, 15 pages, 6 figures (typo corrected and reference added in v2)
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- 2024
3. Non-classical excitation of a solid-state quantum emitter
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Hansen, Lena M., Giorgino, Francesco, Jehle, Lennart, Carosini, Lorenzo, Carreño, Juan Camilo López, Arrazola, Iñigo, Walther, Philip, and Loredo, Juan C.
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Quantum Physics - Abstract
The interaction between a single emitter and a single photon is a fundamental aspect of quantum optics. This interaction allows for the study of various quantum processes, such as emitter-mediated single-photon scattering and effective photon-photon interactions. However, empirical observations of this scenario and its dynamics are rare, and in most cases, only partial approximations to the fully quantized case have been possible. Here, we demonstrate the resonant excitation of a solid-state quantum emitter using quantized input light. For this light-matter interaction, with both entities quantized, we observe single-photon interference introduced by the emitter in a coherent scattering process, photon-number-depended optical non-linearities, and stimulated emission processes involving only two photons. We theoretically reproduce our observations using a cascaded master equation model. Our findings demonstrate that a single photon is sufficient to change the state of a solid-state quantum emitter, and efficient emitter-mediated photon-photon interactions are feasible. These results suggest future possibilities ranging from enabling quantum information transfer in a quantum network to building deterministic entangling gates for photonic quantum computing., Comment: 13 pages, 8 figures
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- 2024
4. Once a Triple, Not Always a Triple: The Evolution of Hierarchical Triples that Yield Merged Inner Binaries
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Shariat, Cheyanne, Naoz, Smadar, El-Badry, Kareem, Rodriguez, Antonio C., Hansen, Bradley M. S., Angelo, Isabel, and Stephan, Alexander P.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
More than half of all main-sequence (MS) stars have one or more companions, and many of those with initial masses <8 M$_\odot$ are born in hierarchical triples. These systems feature two stars in a close orbit (the inner binary) while a tertiary star orbits them on a wider orbit (the outer binary). In hierarchical triples, three-body dynamics combined with stellar evolution drives interactions and, in many cases, merges the inner binary entirely to create a renovated `Post-Merger Binary' (PMB). By leveraging dynamical simulations and tracking binary interactions, we explore the outcomes of merged triples and investigate whether PMBs preserve signatures of their three-body history. Our findings indicate that in 26-54% of wide double WD binaries (s>100 au), the more massive white dwarf (WD) is a merger product, implying that these DWD binaries were previously triples. Overall, we estimate that $44\pm14\%$ of observed wide DWDs originated in triple star systems and thereby have rich dynamical histories. Additionally, our results suggest that the separations of inner and outer binaries are uncorrelated at birth, providing insights into stellar formation processes. We also examine MS+MS and MS+Red Giant mergers manifesting as Blue Straggler stars (BSSs). These PMBs have orbital configurations and ages similar to most observed BSS binaries. While the triple+merger formation channel can explain the observed chemical abundances, moderate eccentricities, and companion masses in BSS binaries, it likely only accounts for $\sim$20-25% of BSSs. Meanwhile, we predict that the majority of observed single BSSs formed as collisions in triples and harbor long-period (>10 yr) companions. Furthermore, both BSS binaries and DWDs exhibit signatures of WD birth kicks., Comment: Accepted for publication to ApJ. Additional comments are welcome
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- 2024
5. Analytical models for secular descents in hierarchical triple systems
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Weldon, Grant C., Naoz, Smadar, and Hansen, Bradley M. S.
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Triple body systems are prevalent in nature, from planetary to stellar to supermassive black hole scales. In a hierarchical triple system, oscillations of the inner orbit's eccentricity and inclination can be induced on secular timescales. Over many cycles, the octupole-level terms in the secular equations of motion can drive the system to extremely high eccentricities via the Eccentric Kozai-Lidov (EKL) mechanism. The overall decrease in the inner orbit's pericenter distance has potentially dramatic effects for realistic systems, such as tidal disruption events. We present an analytical approximation in the test particle limit to describe individual step-wise increases in eccentricity of the inner orbit. A second approximation, also in the test particle limit, is obtained by integrating the equations of motion and calibrating to numerical simulations to estimate the overall octupole-level time evolution of the eccentricity. The latter approach is then extended beyond the test particle to the general case. The three novel analytical approximations are compared to numerical solutions to show that the models accurately describe the form and timescale of the secular descent from large distances to a close-encounter distance (e.g., the Roche limit). By circumventing the need for numerical simulations to obtain the long-term behavior, these approximations can be used to readily estimate properties of close encounters and descent timescales for populations of systems. We demonstrate by calculating rates of EKL-driven migration for Hot Jupiters in stellar binaries., Comment: Accepted to ApJ, 16 pages, 8 figures
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- 2024
6. Widespread disruption of resonant chains during protoplanetary disk dispersal
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Hansen, Brad M. S., Yu, Tze-Yeung, and Hasegawa, Yasuhiro
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Astrophysics - Earth and Planetary Astrophysics - Abstract
We describe the evolution of low mass planets in a dispersing protoplanetary disk around a Solar mass star. The disk model is based on the results of Yu, Hansen & Hasegawa (2023), which describes a region of the inner disk where the direction of the migration torque is outwards due to the diffusion of the stellar magnetic field into the disk and the resultant gradual increase in surface density outwards. We demonstrate that the magnetospheric rebound phase in such a disk leads to diverging orbits for double and triple planet systems, and the disruption of a high fraction of the initial resonant chains. We present simulations of three planet systems with masses based on the observed triple planet systems observed by the Kepler satellite within the context of this model. The final distribution of nearest neighbour period ratios provides an excellent fit to the observations, provided that the initial resonant configurations are compact. The occurrence rate of planets as a function of orbital period also provides a good match to the observations, for final orbital periods P<20 days. These results suggest that the period and period ratio distributions of low mass planets are primarily set in place during the disk dispersal epoch, and may not require significant dynamical evolution thereafter., Comment: 17 pages, 18 figures, to appear in Open Journal of Astrophysics
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- 2024
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7. Purifying photon indistinguishability through quantum interference
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Faurby, Carlos F. D., Carosini, Lorenzo, Cao, Huan, Sund, Patrik I., Hansen, Lena M., Giorgino, Francesco, Villadsen, Andrew B., Hoven, Stefan N. van den, Lodahl, Peter, Paesani, Stefano, Loredo, Juan C., and Walther, Philip
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Quantum Physics - Abstract
Indistinguishability between photons is a key requirement for scalable photonic quantum technologies. We experimentally demonstrate that partly distinguishable single photons can be purified to reach near-unity indistinguishability by the process of quantum interference with ancillary photons followed by heralded detection of a subset of them. We report on the indistinguishability of the purified photons by interfering two purified photons and show improvements in the photon indistinguishability of $2.774(3)$\% in the low-noise regime, and as high as $10.2(5)$ \% in the high-noise regime., Comment: 14 pages, 7 figures
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- 2024
8. Predicting the Dominant Formation Mechanism of Multi-Planetary Systems
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Shariat, Cheyanne, Hasegawa, Yasuhiro, Hansen, Bradley M. S., Yu, Tze Yeung Mathew, and Hu, Renyu
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Most, if not all, sun-like stars host one or more planets, making multi-planetary systems commonplace in our galaxy. We utilize hundreds of multi-planet simulations to explore the origin of such systems, focusing on their orbital architecture. The first set of simulations assumes in-situ assembly of planetary embryos, while the second explores planetary migration. After applying observational biases to the simulations, we compare them to 250+ observed multi-planetary systems, including 13 systems with planets in the habitable zone. For all of the systems, we calculate two of the so-called statistical measures: the mass concentration ($S_{c}$) and orbital spacing ($S_{s}$). After analytic and empirical analyses, we find that the measures are related to first-order with a power law: $S_{c} \sim S_{s}^\beta$. The in-situ systems exhibit steeper power-law relations relative to the migration systems. We show that different formation scenarios cover different regions in the $S_{s} - S_{c}$ diagram with some overlap. Furthermore, we discover that observed systems with $S_{s} < 30$ are likely dominated by the migration scenario, while those with $S_{s} \geq 30$ are likely dominated by the in-situ scenario. We apply these criteria to determine that a majority (62%) of observed multi-planetary systems formed via migration, whereas most systems with currently observed habitable planets formed via in-situ assembly. This work provides methods of leveraging the statistical measures ($S_{s}$ and $S_{c}$) to disentangle the formation history of observed multi-planetary systems based on their present-day architectures., Comment: Accepted for publication in ApJ Letters
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- 2024
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9. Optimizing Grid Resilience: A Capacity Reserve Market for High Impact Low Probability Events
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Salman, Umar T., Wang, Zongjie, and Hansen, Timothy M.
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Electrical Engineering and Systems Science - Systems and Control - Abstract
This paper addresses the challenges of high-impact low-probability (HILP) events by proposing a novel capacity reserve event market for mobile generation assets, aimed at supporting the transmission network during such incidents. Despite the usefulness of portable generators and mobile energy units in restoring power, there are drawbacks such as environmental impact, finite operation, and complex cost recovery. The proposed market integrates these resources into a dispatch framework based on pre-established contracts, ensuring fair compensation and considering factors like capacity, pricing, and travel distance. Resource owners receive advanced notifications for potential events, allowing them to adjust their bids for cost recovery. Simulations on an IEEE 30-bus case have been conducted to demonstrate the model effectiveness in increasing grid resiliency.
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- 2024
10. Preventing excessive autophagy protects from the pathology of mtDNA mutations in Drosophila melanogaster
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El Fissi, Najla, Rosenberger, Florian A., Chang, Kai, Wilhalm, Alissa, Barton-Owen, Tom, Hansen, Fynn M., Golder, Zoe, Alsina, David, Wedell, Anna, Mann, Matthias, Chinnery, Patrick F., Freyer, Christoph, and Wredenberg, Anna
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- 2024
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11. Epigenome-wide analysis across the development span of pediatric acute lymphoblastic leukemia: backtracking to birth
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Ghantous, Akram, Nusslé, Semira Gonseth, Nassar, Farah J., Spitz, Natalia, Novoloaca, Alexei, Krali, Olga, Nickels, Eric, Cahais, Vincent, Cuenin, Cyrille, Roy, Ritu, Li, Shaobo, Caron, Maxime, Lam, Dilys, Fransquet, Peter Daniel, Casement, John, Strathdee, Gordon, Pearce, Mark S., Hansen, Helen M., Lee, Hwi-Ho, Lee, Yong Sun, de Smith, Adam J., Sinnett, Daniel, Håberg, Siri Eldevik, McKay, Jill A., Nordlund, Jessica, Magnus, Per, Dwyer, Terence, Saffery, Richard, Wiemels, Joseph Leo, Munthe-Kaas, Monica Cheng, and Herceg, Zdenko
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- 2024
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12. Glioma immune microenvironment composition calculator (GIMiCC): a method of estimating the proportions of eighteen cell types from DNA methylation microarray data
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Pike, Steven C., Wiencke, John K., Zhang, Ze, Molinaro, Annette M., Hansen, Helen M., Koestler, Devin C., Christensen, Brock C., Kelsey, Karl T., and Salas, Lucas A.
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- 2024
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13. Controlling the photon number coherence of solid-state quantum light sources for quantum cryptography
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Karli, Yusuf, Vajner, Daniel A., Kappe, Florian, Hagen, Paul C. A., Hansen, Lena M., Schwarz, René, Bracht, Thomas K., Schimpf, Christian, Covre da Silva, Saimon F., Walther, Philip, Rastelli, Armando, Axt, Vollrath Martin, Loredo, Juan C., Remesh, Vikas, Heindel, Tobias, Reiter, Doris E., and Weihs, Gregor
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- 2024
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14. Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly
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Murigneux, Emilie, Softic, Laurent, Aubé, Corentin, Grandi, Carmen, Judith, Delphine, Bruce, Johanna, Le Gall, Morgane, Guillonneau, François, Schmitt, Alain, Parissi, Vincent, Berlioz-Torrent, Clarisse, Meertens, Laurent, Hansen, Maike M. K., and Gallois-Montbrun, Sarah
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- 2024
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15. Leveraging Data-Driven Models for Accurate Analysis of Grid-Tied Smart Inverters Dynamics
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Subedi, Sunil, Guruwacharya, Nischal, Poudel, Bidur, Vasquez-Plaza, Jesus D., Andrade, Fabio, Fourney, Robert, Rekabdarkolaee, Hossein Moradi, Hansen, Timothy M., and Tonkoski, Reinaldo
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Electrical Engineering and Systems Science - Systems and Control - Abstract
The integration of power electronic converters (PECs) and distributed energy resources (DERs) in modern power systems has introduced dynamism and complexity. Accurate simulation becomes essential to comprehend the influence of converter domination on the power grid. This study addresses the fast-switching and stochastic behaviors exhibited by inverter-based resources in converter-dominated power systems, highlighting the necessity for precise analytical models. In the realm of modeling real-world systems, multiple methodologies exist. Notably, black-box and data-driven system identification techniques are employed to construct PEC models using experimental data, without relying on a priori knowledge of the internal system physics. This approach entails a systematic process of model class selection, parameter estimation, and model validation. While a range of linear and nonlinear model structures and estimation algorithms are at our disposal, it remains imperative to harness creativity and a profound understanding of the physical system to craft data-driven models that align seamlessly with their intended applications. These applications may encompass simulation, prediction, control, or fault detection. This report offers valuable insights into the collection of datasets from commercial off-the-shelf inverters, along with the presentation of intricate simulation models., Comment: 9 pages, 7 figures
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- 2023
16. Bound circumplanetary orbits under the influence of radiation pressure: Application to dust in directly imaged exoplanet systems
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Hansen, Brad M. S. and Hayakawa, Kevin
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Astrophysics - Earth and Planetary Astrophysics - Abstract
We examine the population of simply periodic orbits in the Hill problem with radiation pressure included, in order to understand the distribution of gravitationally bound dust in orbit around a planet. We study a wide range of radiation pressure strengths, which requires the inclusion of additional terms beyond those discussed in previous analyses of this problem. In particular, our solutions reveal two distinct populations of stable wide, retrograde, orbits, as opposed to the single family that exists in the purely gravitational problem. We use the result of these calculations to study the observational shape of dust populations bound to extrasolar planets, that might be observable in scattered or reradiated light. In particular, we find that such dusty clouds should be elongated along the star--planet axis, and that the elongation of the bound population increases with $\beta$, a measure of the strength of the radiation pressure. As an application of this model, we consider the properties of the Fomalhaut system. The unusual orbital properties of the object Fomalhaut~b can be explained if the observed light was scattered by dust that was released from an object in a quasi-satellite orbit about a planet located in, or near, the observed debris ring. Within the context of the model of Hayakawa \& Hansen (2023), we find that the dust cloud around such a planet is still approximately an order of magnitude fainter than the limits set by current JWST data., Comment: 21 pages, 22 figures
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- 2023
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17. A photonic source of heralded GHZ states
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Cao, H., Hansen, L. M., Giorgino, F., Carosini, L., Zahalka, P., Zilk, F., Loredo, J. C., and Walther, P.
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Quantum Physics - Abstract
Generating large multiphoton entangled states is of main interest due to enabling universal photonic quantum computing and all-optical quantum repeater nodes. These applications exploit measurement-based quantum computation using cluster states. Remarkably, it was shown that photonic cluster states of arbitrary size can be generated by using feasible heralded linear optics fusion gates that act on heralded three-photon Greenberger-Horne-Zeilinger (GHZ) states as the initial resource state. Thus, the capability of generating heralded GHZ states is of great importance for scaling up photonic quantum computing. Here, we experimentally demonstrate this required building block by reporting a polarisation-encoded heralded GHZ state of three photons, for which we build a high-rate six-photon source ($547{\pm}2$ Hz) from a solid-state quantum emitter and a stable polarisation-based interferometer. The detection of three ancillary photons heralds the generation of three-photon GHZ states among the remaining particles with fidelities up to $\mathcal{F}=0.7278{\pm}0.0106$. Our results initiate a path for scalable entangling operations using heralded linear-optics implementations., Comment: 6 pages, 5 figures
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- 2023
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18. Correction: p73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis
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Sayan, A. E., Sayan, B. S., Gogvadze, V., Dinsdale, D., Nyman, U., Hansen, T. M., Zhivotovsky, B., Cohen, G. M., Knight, R. A., and Melino, G.
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- 2025
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19. Oligodendroglioma patient survival is associated with circulating B-cells and age
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Taylor, Jennie W, Warrier, Gayathri, Hansen, Helen M, McCoy, Lucie, Rice, Terri, Guerra, Geno, Francis, Stephen S, Clarke, Jennifer L, Bracci, Paige M, Hadad, Sara, Kelsey, Karl T, Wrensch, Margaret, Molinaro, Annette M, and Wiencke, John K
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Biomedical and Clinical Sciences ,Oncology and Carcinogenesis ,Immunology ,Brain Disorders ,Neurosciences ,Brain Cancer ,Rare Diseases ,Cancer ,Clinical Research ,2.1 Biological and endogenous factors ,epigenetics ,glioma ,immune factors ,immunomethylomics ,oligodendroglioma - Abstract
BackgroundVariations in survival among patients with oligodendroglioma are unexplained by known prognostic factors. To assess the impact of peripheral immune profiles on prognosis, we applied immunomethylomics analyses-DNA methylation of archived whole blood samples, to characterize immune cells.MethodsWe compared the proportions of immune cells from patients with oligodendroglioma to other glioma subtypes and controls. We used recursive partitioning analysis (RPA) within the oligodendrogliomas to correlate with survival.ResultsPatients with oligodendrogliomas (141) were median age at diagnosis of 44 years; 57% male; 75% White; 60% prior chemotherapy; and 25% on dexamethasone at sample collection. Patients with oligodendrogliomas had immune profiles more similar to controls than other glioma subtypes, though with notably lower B-cells. RPA of patients with oligodendrogliomas delineated 2 survival groups based on an interaction between age and B-naïve cells. Patients with longer survival (median 24.2 years) were ≤42 years of age with higher B-naïve cells versus worse survival (median 16.9 years) who were ≤42 years of age with lower B-naïve cells or >42 years of age (P = .00032). Patients with worse survival also had lower CD4- and CD8-naïve T-cells. Similar immune profiles were observed in an independent cohort of oligodendroglioma patients prior to surgery.ConclusionsPeripheral blood immune profiles in oligodendroglioma suggested that younger patients with lower B-naïve cells experienced shorter survival. Though our findings lack of validation cohort and use a heterogenous patient population, they suggest peripheral blood immune profiles may be prognostic for patients with glioma and warrant further investigation.
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- 2024
20. Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity
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Jiang, Shan, Yuan, Taolin, Rosenberger, Florian A., Mourier, Arnaud, Dragano, Nathalia R. V., Kremer, Laura S., Rubalcava-Gracia, Diana, Hansen, Fynn M., Borg, Melissa, Mennuni, Mara, Filograna, Roberta, Alsina, David, Misic, Jelena, Koolmeister, Camilla, Papadea, Polyxeni, de Angelis, Martin Hrabe, Ren, Lipeng, Andersson, Olov, Unger, Anke, Bergbrede, Tim, Di Lucrezia, Raffaella, Wibom, Rolf, Zierath, Juleen R., Krook, Anna, Giavalisco, Patrick, Mann, Matthias, and Larsson, Nils-Göran
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- 2024
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21. Submersion Injuries and the Cost of Injury Associated with Drowning Events in the United States, 2006–2015
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Hansen, Regina M., Agana-Norman, Denny Fe G., Hufton, Amie, and Hansen, Michael A.
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- 2024
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22. Automated Data-Driven Model Extraction and Validation of Inverter Dynamics with Grid Support Function
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Subedi, Sunil, Poudel, Bidur, Aslami, Pooja, Fourney, Robert, Rekabdarkolaee, Hossein Moradi, Tonkoski, Reinaldo, and Hansen, Timothy M.
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Electrical Engineering and Systems Science - Systems and Control - Abstract
This research focuses on the evolving dynamics of the power grid, where traditional synchronous generators are being replaced by non-synchronous power electronic converter (PEC)-interfaced renewable energy sources. The non-linear dynamics must be accurately modeled to ensure the stability of future converter-dominated power systems (CDPS). However, obtaining comprehensive dynamic models becomes more complex and computationally intensive as the system grows. This study proposes a scalable and automated data-driven partitioned modeling framework for CDPS dynamics. The method constructs reduced-ordered dynamic linear transfer function models using input-output measurements from a PEC switching model. Validation experiments were conducted on single-house and multi-house scenarios, demonstrating high accuracy (over 97%) and significant computational speed improvements (6.5 times faster) compared to comprehensive models. This framework and modeling approach offers valuable insights for efficient analysis of power system dynamics, aiding in planning, operation, and dispatch.
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- 2023
23. Dynamical Evolution of White Dwarfs in Triples in the Era of Gaia
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Shariat, Cheyanne, Naoz, Smadar, Hansen, Bradley M. S., Angelo, Isabel, Michaely, Erez, and Stephan, Alexander P.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
The $Gaia$ mission has detected many white dwarfs (WDs) in binary and triple configurations, and while observations suggest that triple stellar systems are common in our Galaxy, not much attention was devoted to WDs in triples. For stability reasons, these triples must have hierarchical configurations, i.e., two stars are on a tight orbit (the inner binary), with the third companion on a wider orbit about the inner binary. In such a system, the two orbits torque each other via the eccentric Kozai-Lidov mechanism (EKL), which can alter the orbital configuration of the inner binary. We simulate thousands of triple stellar systems for over $10$ Gyr, tracking gravitational interactions, tides, general relativity, and stellar evolution up to their WD fate. As demonstrated here, three-body dynamics coupled with stellar evolution is a critical channel to form tight WD binaries or merge a WD binary. Amongst these triples, we explore their manifestations as cataclysmic variables, Type Ia supernovae, and gravitational-wave events. The simulated systems are then compared to a sample of WD triples selected from the $Gaia$ catalog. We find that including the effect of mass loss-induced kicks is crucial for producing a distribution of the inner binary-tertiary separations that is consistent with $Gaia$ observations. Lastly, we leverage this consistency to estimate that, at minimum, $30\%$ of solar-type stars in the local $200$ parsecs were born in triples., Comment: 18 pages, 7 figures, revised version accepted for publication in ApJ
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- 2023
24. Programmable multi-photon quantum interference in a single spatial mode
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Carosini, Lorenzo, Oddi, Virginia, Giorgino, Francesco, Hansen, Lena M., Seron, Benoit, Piacentini, Simone, Guggemos, Tobias, Agresti, Iris, Loredo, Juan Carlos, and Walther, Philip
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Quantum Physics - Abstract
The interference of non-classical states of light enables quantum-enhanced applications reaching from metrology to computation. Most commonly, the polarisation or spatial location of single photons are used as addressable degrees-of-freedom for turning these applications into praxis. However, the scale-up for the processing of a large number of photons of such architectures is very resource demanding due to the rapidily increasing number of components, such as optical elements, photon sources and detectors. Here we demonstrate a resource-efficient architecture for multi-photon processing based on time-bin encoding in a single spatial mode. We employ an efficient quantum dot single-photon source, and a fast programmable time-bin interferometer, to observe the interference of up to 8 photons in 16 modes, all recorded only with one detector--thus considerably reducing the physical overhead previously needed for achieving equivalent tasks. Our results can form the basis for a future universal photonics quantum processor operating in a single spatial mode., Comment: 8 pages, 5 figures
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- 2023
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25. Coronal Heating as Determined by the Solar Flare Frequency Distribution Obtained by Aggregating Case Studies
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Mason, James Paul, Werth, Alexandra, West, Colin G., Youngblood, Allison A., Woodraska, Donald L., Peck, Courtney, Lacjak, Kevin, Frick, Florian G., Gabir, Moutamen, Alsinan, Reema A., Jacobsen, Thomas, Alrubaie, Mohammad, Chizmar, Kayla M., Lau, Benjamin P., Dominguez, Lizbeth Montoya, Price, David, Butler, Dylan R., Biron, Connor J., Feoktistov, Nikita, Dewey, Kai, Loomis, N. E., Bodzianowski, Michal, Kuybus, Connor, Dietrick, Henry, Wolfe, Aubrey M., Guerrero, Matt, Vinson, Jessica, Starbuck, Peter, Litton, Shelby D, Beck, M. G., Fisch, Jean-Paul, West, Ayana, Muniz, Alexis A., Chavez, Luis, Upthegrove, Zachary T., Runyon, Brenton M., Salazar, J., Kritzberg, Jake E., Murrel, Tyler, Ho, Ella, LaFemina, Quintin Y., Elbashir, Sara I., Chang, Ethan C., Hudson, Zachary A., Nussbaum, Rosemary O., Kennedy, Kellen, Kim, Kevin, Arango, Camila Villamil, Albakr, Mohammed A., Rotter, Michael, Garscadden, A. J., Salcido-Alcontar JR, Antonio, Pearl, Harrison M., Stepaniak, Tyler, Marquez, Josie A., Marsh, Lauren, Andringa, Jesse C, Osogwin, Austin, Shields, Amanda M., Brookins, Sarah, Hach, Grace K., Clausi, Alexis R., Millican, Emily B., Jaimes, Alan A, Graham, Alaina S., Burritt, John J., Perez, J. S., Ramirez, Nathaniel, Suri, Rohan, Myer, Michael S., Kresek, Zoe M., Goldsberry, C. A., Payne, Genevieve K., Jourabchi, Tara, Hu, J., Lucca, Jeffrey, Feng, Zitian, Gilpatrick, Connor B., Khan, Ibraheem A., Warble, Keenan, Sweeney, Joshua D., Dorricott, Philip, Meyer, Ethan, Kothamdi, Yash S., Sohail, Arman S., Grell, Kristyn, Floyd, Aidan, Bard, Titus, Mathieson, Randi M., Reed, Joseph, Cisneros, Alexis, Payne, Matthew P., Jarriel, J. R., Mora, Jacqueline Rodriguez, Sundell, M. E., Patel, Kajal, Alesmail, Mohammad, Alnasrallah, Yousef A, Abdullah, Jumana T., Molina-Saenz, Luis, Tayman, K. E., Brown, Gabriel T., Kerr-Layton, Liana, Berriman-Rozen, Zachary D., Hiatt, Quinn, Kalra, Etash, Ong, Jason, Vadayar, Shreenija, Shannahan, Callie D., Benke, Evan, zhang, Jinhua, Geisman, Jane, Martyr, Cara, Ameijenda, Federico, Akruwala, Ushmi H., Nehring, Molly, Kissner, Natalie, Rule, Ian C., Learned, Tyler, Smith, Alexandra N., Mazzotta, Liam, Rounsefell, Tyndall, Eyeson, Elizabeth A., Shelby, Arlee K., Moll, Tyler S, Menke, Riley, Shahba, Hannan, House Jr., Tony A., Clark, David B., Burns, Annemarie C., de La Beaujardiere, Tristan, Trautwein, Emily D., Plantz, Will, Reeves, Justin, Faber, Ian, Buxton, B. W., Highhouse, Nigel, Landrey, Kalin, Hansen, Connor M, Chen, Kevin, Hales, Ryder Buchanan, Borgerding, Luke R., Guo, Mutian, Crow, Christian J., Whittall, Lloyd C., Simmons, Conor, Folarin, Adeduni, Parkinson, Evan J., Rahn, Anna L., Blevins, Olivia, Morelock, Annalise M., Kelly, Nicholas, Parker, Nathan L., Smith, Kelly, Plzak, Audrey E., Saeb, David, Hares, Cameron T., Parker, Sasha R., McCoy, Andrew, Pham, Alexander V., Lauzon, Megan, Kennedy, Cayla J., Reyna, Andrea B., Acosta, Daniela M. Meza, Cool, Destiny J., Steinbarth, Sheen L., Mendoza-Anselmi, Patricia, Plutt, Kaitlyn E., Kipp, Isabel M, Rakhmonova, M., Brown, Cameron L., Van Anne, Gabreece, Moss, Alexander P., Golden, Olivia, Kirkpatrick, Hunter B., Colleran, Jake R., Sullivan, Brandon J, Tran, Kevin, Carpender, Michael Andrew, Mundy, Aria T., Koenig, Greta, Oudakker, Jessica, Engelhardt, Rasce, Ales, Nolan, Wexler, Ethan Benjamin, Beato, Quinn I, Chen, Lily, Cochran, Brooke, Hill, Paula, Hamilton, Sean R., Hashiro, Kyle, Khan, Usman, Martinez, Alexa M., Brockman, Jennifer L., Mallory, Macguire, Reed, Charlie, Terrile, Richard, Singh, Savi, Watson, James Adam, Creany, Joshua B., Price, Nicholas K., Miften, Aya M., Tran, Bryn, Kamenetskiy, Margaret, Martinez, Jose R., Opp, Elena N., Huang, Jianyang, Fails, Avery M., Belei, Brennan J., Slocum, Ryan, Astalos, Justin, East, Andrew, Nguyen, Lena P., Pherigo, Callie C, East, Andrew N., Li, David Y., Nelson, Maya LI, Taylor, Nicole, Odbayar, Anand, Rives, Anna Linnea, Mathur, Kabir P., Billingsley, Jacob, Polikoff, Hyden, Driscoll, Michael, Wilson, Orion K., Lahmers, Kyle, Toon, Nathaniel J., Lippincott, Sam, Musgrave, Andrew J., Gregory, Alannah H., Pitsuean-Meier, Sedique, Jesse, Trevor, Smith, Corey, Miles, Ethan J., Kainz, Sabrina J. H. T., Ji, Soo Yeun, Nguyen, Lena, Aryan, Maryam, Dinser, Alexis M., Shortman, Jadon, Bastias, Catalina S, Umbricht, Thomas D, Cage, Breonna, Randolph, Parker, Pollard, Matthew, Simone, Dylan M., Aramians, Andrew, Brecl, Ariana E., Robert, Amanda M., Zenner, Thomas, Saldi, Maxwell, Morales, Gavin, Mendez, Citlali, Syed, Konner, Vogel, Connor Maklain, Cone, Rebecca A., Berhanu, Naomi, Carpenter, Emily, Leoni, Cecilia, Bryan, Samuel, Ramachandra, Nidhi, Shaw, Timothy, Lee, E. C., Monyek, Eli, Wegner, Aidan B., Sharma, Shajesh, Lister, Barrett, White, Jamison R., Willard, John S., Sulaiman, S. A, Blandon, Guillermo, Narayan, Anoothi, Ruger, Ryan, Kelley, Morgan A., Moreno, Angel J., Balcer, Leo M, Ward-Chene, N. R. D., Shelby, Emma, Reagan, Brian D., Marsh, Toni, Sarkar, Sucheta, Kelley, Michael P., Fell, Kevin, Balaji, Sahana, Hildebrand, Annalise K., Shoha, Dominick, Nandu, Kshmya, Tucker, Julia, Cancio, Alejandro R., Wang, Jiawei, Rapaport, Sarah Grace, Maravi, Aimee S., Mayer, Victoria A., Miller, Andrew, Bence, Caden, Koke, Emily, Fauntleroy, John T, Doermer, Timothy, Al-Ghazwi, Adel, Morgan, Remy, Alahmed, Mohammed S., Mathavan, Adam Izz Khan Mohd Reduan, Silvester, H. K., Weiner, Amanda M., Liu, Nianzi, Iovan, Taro, Jensen, Alexander V., AlHarbi, Yazeed A., Jiang, Yufan, Zhang, Jiaqi, Jones, Olivia M., Huang, Chenqi, Reh, Eileen N., Alhamli, Dania, Pettine, Joshua, Zhou, Chongrui, Kriegman, Dylan, Yang, Jianing, Ash, Kevin, Savage, Carl, Kaiser, Emily, Augenstein, Dakota N., Padilla, Jacqueline, Stark, Ethan K., Hansen, Joshua A., Kokes, Thomas, Huynh, Leslie, Sanchez-Sanchez, Gustavo, Jeseritz, Luke A., Carillion, Emma L., Vepa, Aditya V., Khanal, Sapriya, Behr, Braden, Martin, Logan S., McMullan, Jesse J., Zhao, Tianwei, Williams, Abigail K., Alqabani, Emeen, Prinster, Gale H., Horne, Linda, Ruggles-Delgado, Kendall, Otto, Grant, Gomez, Angel R., Nguyen, Leonardo, Brumley, Preston J., Venegas, Nancy Ortiz, Varela, Ilian, Brownlow, Jordi, Cruz, Avril, Leiker, Linzhi, Batra, Jasleen, Hutabarat, Abigail P., Nunes-Valdes, Dario, Jameson, Connor, Naqi, Abdulaziz, Adams, Dante Q., Biediger, Blaine B., Borelli, William T, Cisne, Nicholas A., Collins, Nathaniel A., Curnow, Tyler L., Gopalakrishnan, Sean, Griffin, Nicholas F., Herrera, Emanuel, McGarvey, Meaghan V., Mellett, Sarah, Overchuk, Igor, Shaver, Nathan, Stratmeyer, Cooper N., Vess, Marcus T., Juels, Parker, Alyami, Saleh A., Gale, Skylar, Wallace, Steven P., Hunter, Samuel C, Lonergan, Mia C., Stewart, Trey, Maksimuk, Tiffany E., Lam, Antonia, Tressler, Judah, Napoletano, Elena R., Miller, Joshua B., Roy, Marc G., Chanders, Jasey, Fischer, Emmalee, Croteau, A. J., Kuiper, Nicolas A., Hoffman, Alex, DeBarros, Elyse, Curry, Riley T., Brzostowicz, A., Courtney, Jonas, Zhao, Tiannie, Szabo, Emi, Ghaith, Bandar Abu, Slyne, Colin, Beck, Lily, Quinonez, Oliver, Collins, Sarah, Madonna, Claire A., Morency, Cora, Palizzi, Mallory, Herwig, Tim, Beauprez, Jacob N., Ghiassi, Dorsa, Doran, Caroline R., Yang, Zhanchao, Padgette, Hannah M., Dicken, Cyrus A., Austin, Bryce W., Phalen, Ethan J., Xiao, Catherine, Palos, Adler, Gerhardstein, Phillip, Altenbern, Ava L., Orbidan, Dan, Dorr, Jackson A., Rivas, Guillermo A., Ewing, Calvin A, Giebner, B. C., McEntee, Kelleen, Kite, Emily R., Crocker, K. A., Haley, Mark S., Lezak, Adrienne R., McQuaid, Ella, Jeong, Jacob, Albaum, Jonathan, Hrudka, E. M., Mulcahy, Owen T., Tanguma, Nolan C., Oishi-Holder, Sean, White, Zachary, Coe, Ryan W., Boyer, Christine, Chapman, Mitchell G., Fortino, Elise, Salgado, Jose A., Hellweg, Tim, Martinez, Hazelia K., Mitchell, Alexander J., Schubert, Stephanie H., Schumacher, Grace K, Tesdahl, Corey D, Uphoff, C. H., Vassilyev, Alexandr, Witkoff, Briahn, Wolle, Jackson R., Dice, Kenzie A., Behrer, Timothy A., Bowen, Troy, Campbell, Andrew J, Clarkson, Peter C, Duong, Tien Q., Hawat, Elijah, Lopez, Christian, Olson, Nathaniel P., Osborn, Matthew, Peou, Munisettha E., Vaver, Nicholas J., Husted, Troy, Kallemeyn, Nicolas Ian, Spangler, Ava A, Mccurry, Kyle, Schultze, Courtney, Troisi, Thomas, Thomas, Daniel, Ort, Althea E., Singh, Maya A., Soon, Caitlin, Patton, Catherine, Billman, Jayce A., Jarvis, Sam, Hitt, Travis, Masri, Mirna, Albalushi, Yusef J., Schofer, Matthew J, Linnane, Katherine B., Knott, Philip Whiting, Valencia, Whitney, Arias-Robles, Brian A., Ryder, Diana, Simone, Anna, Abrams, Jonathan M., Belknap, Annelene L., Rouse, Charlotte, Reynolds, Alexander, Petric, Romeo S. L., Gomez, Angel A., Meiselman-Ashen, Jonah B., Carey, Luke, Dias, John S., Fischer-White, Jules, Forbes, Aidan E., Galarraga, Gabriela, Kennedy, Forrest, Lawlor, Rian, Murphy, Maxwell J., Norris, Cooper, Quarderer, Josh, Waller, Caroline, Weber, Robert J., Gunderson, Nicole, Boyne, Tom, Gregory, Joshua A., Propper, Henry Austin, von Peccoz, Charles B. Beck, Branch, Donovan, Clarke, Evelyn, Cutler, Libby, Dabberdt, Frederick M., Das, Swagatam, Figueirinhas, John Alfred D., Fougere, Benjamin L., Roy, Zoe A., Zhao, Noah Y., Cox, Corben L., Barnhart, Logan D. W., Craig, Wilmsen B., Moll, Hayden, Pohle, Kyle, Mueller, Alexander, Smith, Elena K., Spicer, Benjamin C., Aycock, Matthew C., Bat-Ulzii, Batchimeg, Murphy, Madalyn C., Altokhais, Abdullah, Thornally, Noah R., Kleinhaus, Olivia R., Sarfaraz, Darian, Barnes, Grant M., Beard, Sara, Banda, David J, Davis, Emma A. B., Huebsch, Tyler J., Wagoner, Michaela, Griego, Justus, Hale, Jack J. Mc, Porter, Trevor J., Abrashoff, Riley, Phan, Denise M., Smith, Samantha M., Srivastava, Ashish, Schlenker, Jared A. W., Madsen, Kasey O., Hirschmann, Anna E., Rankin, Frederick C, Akbar, Zainab A., Blouin, Ethan, Coleman-Plante, Aislinn, Hintsa, Evan, Lookhoff, Emily, Amer, Hamzi, Deng, Tianyue, Dvorak, Peter, Minimo, Josh, Plummer, William C., Ton, Kelly, Solt, Lincoln, AlAbbas, Batool H., AlAwadhi, Areej A., Cooper, Nicholas M., Corbitt, Jessica S, Dunlap, Christian, Johnson, Owen, Malone, Ryan A., Tellez, Yesica, Wallace, Logan, Ta, Michael-Tan D., Wheeler, Nicola H., Ramirez, Ariana C., Huang, Shancheng, Mehidic, Amar, Christiansen, Katherine E, Desai, Om, Domke, Emerson N., Howell, Noah H., Allsbrook, Martin, Alnaji, Teeb, England, Colin, Siles, Nathan, Burton, Nicholas David, Cruse, Zoe, Gilmartin, Dalton, Kim, Brian T., Hattendorf, Elsie, Buhamad, Maryam, Gayou, Lily, Seglem, Kasper, Alkhezzi, Tameem, Hicks, Imari R., Fife, Ryann, Pelster, Lily M., Fix, Alexander, Sur, Sohan N., Truong, Joshua K., Kubiak, Bartlomiej, Bondar, Matthew, Shi, Kyle Z., Johnston, Julia, Acevedo, Andres B., Lee, Junwon, Solorio, William J., Johnston, Braedon Y., McCormick, Tyler, Olguin, Nicholas, Pastor, Paige J., Wilson, Evan M., Trunko, Benjamin L., Sjoroos, Chris, Adams, Kalvyn N, Bell, Aislyn, Brumage-Heller, Grant, Canales, Braden P., Chiles, Bradyn, Driscoll, Kailer H., Hill, Hallie, Isert, Samuel A., Ketterer, Marilyn, Kim, Matthew M., Mewhirter, William J., Phillips, Lance, Phommatha, Krista, Quinn, Megan S., Reddy, Brooklyn J., Rippel, Matthew, Russell, Bowman, Williams, Sajan, Pixley, Andrew M., Gapin, Keala C., Peterson, B., Ruprecht, Collin, Hardie, Isabelle, Li, Isaac, Erickson, Abbey, Gersabeck, Clint, Gopalani, Mariam, Allanqawi, Nasser, Burton, Taylor, Cahn, Jackson R., Conti, Reese, White, Oliver S., Rojec, Stewart, Hogen, Blake A., Swartz, Jason R., Dick, R., Battist, Lexi, Dunn, Gabrielle M., Gasser, Rachel, Logan, Timothy W., Sinkovic, Madeline, Schaller, Marcus T., Heintz, Danielle A., Enrich, Andrew, Sanchez, Ethan S., Perez, Freddy, Flores, Fernando, Kapla, Shaun D., Shockley, Michael C., Phillips, Justin, Rumley, Madigan, Daboub, Johnston, Karsh, Brennan J., Linders, Bridget, Chen, Sam, Do, Helen C., Avula, Abhinav, French, James M., Bertuccio, Chrisanna, Hand, Tyler, Lee, Adrianna J., Neeland, Brenna K, Salazar, Violeta, Andrew, Carter, Barmore, Abby, Beatty, Thomas, Alonzi, Nicholas, Brown, Ryan, Chandler, Olivia M., Collier, Curran, Current, Hayden, Delasantos, Megan E., Bonilla, Alberto Espinosa de los Monteros, Fowler, Alexandra A., Geneser, Julianne R., Gentry, Eleanor, Gustavsson, E. R., Hansson, Jonathan, Hao, Tony Yunfei, Herrington, Robert N., Kelly, James, Kelly, Teagan, Kennedy, Abigail, Marquez, Mathew J., Meillon, Stella, Palmgren, Madeleine L., Pesce, Anneliese, Ranjan, Anurag, Robertson, Samuel M., Smith, Percy, Smith, Trevor J, Soby, Daniel A., Stratton, Grant L., Thielmann, Quinn N., Toups, Malena C., Veta, Jenna S., Young, Trenton J., Maly, Blake, Manzanares, Xander R., Beijer, Joshua, George, Jacob D., Mills, Dylan P., Ziebold, Josh J, Chambers, Paige, Montoya, Michael, Cheang, Nathan M., Anderson, Hunter J., Duncan, Sheridan J., Ehrlich, Lauren, Hudson, Nathan C., Kiechlin, Jack L., Koch, Will, Lee, Justin, Menassa, Dominic, Oakes, S. H., Petersen, Audrey J., Bunsow, J. R. Ramirez, Bay, Joshua, Ramirez, Sacha, Fenwick, Logan D., Boyle, Aidan P., Hibbard, Lea Pearl, Haubrich, Calder, Sherry, Daniel P., Jenkins, Josh, Furney, Sebastian, Velamala, Anjali A., Krueger, Davis J., Thompson, William N., Chhetri, Jenisha, Lee, Alexis Ying-Shan, Ray, Mia G. V., Recchia, John C., Lengerich, Dylan, Taulman, Kyle, Romero, Andres C., Steward, Ellie N., Russell, Sloan, Hardwick, Dillon F., Wootten, Katelynn, Nguyen, Valerie A., Quispe, Devon, Ragsdale, Cameron, Young, Isabel, Atchley-Rivers, N. S., Stribling, Jordin L., Gentile, Julia G, Boeyink, Taylor A., Kwiatkowski, Daniel, Dupeyron, Tomi Oshima, Crews, Anastasia, Shuttleworth, Mitchell, Dresdner, Danielle C., Flackett, Lydia, Haratsaris, Nicholas, Linger, Morgan I, Misener, Jay H., Patti, Samuel, Pine, Tawanchai P., Marikar, Nasreen, Matessi, Giorgio, Routledge, Allie C., Alkaabi, Suhail, Bartman, Jessica L., Bisacca, Gabrielle E., Busch, Celeste, Edwards, Bree, Staudenmier, Caitlyn, Starling, Travis, McVey, Caden, Montano, Maximus, Contizano, Charles J., Taylor, Eleanor, McIntyre, James K., Victory, Andrew, McCammon, Glen S., Kimlicko, Aspen, Sheldrake, Tucker, Shelchuk, Grace, Von Reich, Ferin J., Hicks, Andrew J., O'neill, Ian, Rossman, Beth, Taylor, Liam C., MacDonald, William, Becker, Simone E., Han, Soonhee, O'Sullivan, Cian, Wilcove, Isaac, Brennan, David J., Hanley, Luke C., Hull, Owen, Wilson, Timothy R., Kalmus, Madison H., Berv, Owen A., Harris, Logan Swous, Doan, Chris H, Londres, Nathan, Parulekar, Anish, Adam, Megan M., Angwin, Abigail, Cabbage, Carter C., Colleran, Zachary, Pietras, Alex, Seux, Octave, Oros, Ryan, Wilkinson, Blake C., Nguyen, Khoa D, Trank-Greene, Maedee, Barone, Kevin M., Snyder, G. L., Biehle, Samuel J, Billig, Brennen, Almquist, Justin Thomas, Dixon, Alyssa M., Erickson, Benjamin, Evans, Nathan, Genne, SL, Kelly, Christopher M, Marcus, Serafima M., Ogle, Caleb, Patel, Akhil, Vendetti, Evan, Courtney, Olivia, Deel, Sean, Del Foco, Leonardo, Gjini, Michael, Haines, Jessica, Hoff, Isabelle J., Jones, M. R., Killian, Dominic, Kuehl, Kirsten, Kuester, Chrisanne, Lantz, Maxwell B., Lee, Christian J, Mauer, Graham, McKemey, Finbar K., Millican, Sarah J., Rosasco, Ryan, Stewart, T. C., VanEtten, Eleanor, Derwin, Zachary, Serio, Lauren, Sickler, Molly G., Blake, Cassidy A., Patel, Neil S., Fox, Margaret, Gray, Michael J, Ziegler, Lucas J., Kumar, Aman Priyadarshi, Polly, Madelyn, Mesgina, Sarah, McMorris, Zane, Griffin, Kyle J., Haile, L. N., Bassel, Claire, Dixon, Thomas J., Beattie, Ryan, Houck, Timothy J, Rodgers, Maeve, Trofino, Tyson R., Lukianow, Dax, Smart, Korben, Hall, Jacqueline L., Bone, Lauren, Baldwin, James O., Doane, Connor, Almohsen, Yousef A., Stamos, Emily, Acha, Iker, Kim, Jake, Samour II, Antonio E., Chavali, S., Kanokthippayakun, Jeerakit, Gotlib, Nicholas, Murphy, Ryan C., Archibald, Jack. W., Brimhall, Alexander J, Boyer, Aidan, Chapman, Logan T., Chadda, Shivank, Sibrell, Lisa, Vallery, Mia M., Conroy, Thomas C., Pan, Luke J., Balajonda, Brian, Fuhrman, Bethany E. S., Alkubaisi, Mohamed, Engelstad, Jacob, Dodrill, Joshua, Fuchs, Calvin R., Bullard-Connor, Gigi, Alhuseini, Isehaq, Zygmunt, James C., Sipowicz, Leo, Hayrynen, Griffin A., McGill, Riley M., Keating, Caden J., Hart, Omer, Cyr, Aidan St., Steinsberger, Christopher H., Thoman, Gerig, Wood, Travis M., Ingram, Julia A., Dominguez, J., Georgiades, Nathaniel James, Johnson, Matthew, Johnson, Sawyer, Pedersen, Alexander J., Ralapanawe, Anoush K, Thomas, Jeffrey J., Sato, Ginn A., Reynolds, Hope, Nasser, Liebe, Mizzi, Alexander Z., Damgaard, Olivia, Baflah, Abdulrahman A., Liu, Steven Y., Salindeho, Adam D., Norden, Kelso, Gearhart, Emily E., Krajnak, Zack, Szeremeta, Philip, Amos, Meggan, Shin, Kyungeun, Muckenthaler, Brandon A., Medialdea, Melissa, Beach, Simone, Wilson, Connor B., Adams, Elena R, Aldhamen, Ahmed, Harris, Coyle M., Hesse, Troy M., Golding, Nathan T., Larter, Zachary, Hernandez, Angel, Morales, Genaro, Traxler, Robert B., Alosaimi, Meshal, Fitton, Aidan F., Aaron, James Holland, Lee, Nathaniel F., Liao, Ryan Z., Chen, Judy, French, Katherine V., Loring, Justin, Colter, Aurora, McConvey, Rowan, Colozzi, Michael, Vann, John D., Scheck, Benjamin T., Weigand, Anthony A, Alhabeeb, Abdulelah, Idoine, Yolande, Woodard, Aiden L., Medellin, Mateo M., Ratajczyk, Nicholas O, Tobin, Darien P., Collins, Jack C., Horning, Thomas M., Pellatz, Nick, Pitten, John, Lordi, Noah, Patterson, Alyx, Hoang, Thi D, Zimmermann, Ingrid H, Wang, Hongda, Steckhahn, Daniel, Aradhya, Arvind J., Oliver, Kristin A., Cai, Yijian, Wang, Chaoran, Yegovtsev, Nikolay, Wu, Mengyu, Ganesan, Koushik, Osborne, Andrew, Wickenden, Evan, Meyer, Josephine C., Chaparro, David, Visal, Aseem, Liu, Haixin, Menon, Thanmay S., Jin, Yan, Wilson, John, Erikson, James W., Luo, Zheng, Shitara, Nanako, Nelson, Emma E, Geerdts, T. R., Ortiz, Jorge L Ramirez, and Lewandowski, H. J.
- Subjects
Astrophysics - Solar and Stellar Astrophysics - Abstract
Flare frequency distributions represent a key approach to addressing one of the largest problems in solar and stellar physics: determining the mechanism that counter-intuitively heats coronae to temperatures that are orders of magnitude hotter than the corresponding photospheres. It is widely accepted that the magnetic field is responsible for the heating, but there are two competing mechanisms that could explain it: nanoflares or Alfv\'en waves. To date, neither can be directly observed. Nanoflares are, by definition, extremely small, but their aggregate energy release could represent a substantial heating mechanism, presuming they are sufficiently abundant. One way to test this presumption is via the flare frequency distribution, which describes how often flares of various energies occur. If the slope of the power law fitting the flare frequency distribution is above a critical threshold, $\alpha=2$ as established in prior literature, then there should be a sufficient abundance of nanoflares to explain coronal heating. We performed $>$600 case studies of solar flares, made possible by an unprecedented number of data analysts via three semesters of an undergraduate physics laboratory course. This allowed us to include two crucial, but nontrivial, analysis methods: pre-flare baseline subtraction and computation of the flare energy, which requires determining flare start and stop times. We aggregated the results of these analyses into a statistical study to determine that $\alpha = 1.63 \pm 0.03$. This is below the critical threshold, suggesting that Alfv\'en waves are an important driver of coronal heating., Comment: 1,002 authors, 14 pages, 4 figures, 3 tables, published by The Astrophysical Journal on 2023-05-09, volume 948, page 71
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- 2023
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26. Debris Rings from Extrasolar Irregular Satellites
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Hayakawa, Kevin T. and Hansen, Bradley M. S.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Irregular satellites are the minor bodies found orbiting all four Solar System giant planets, with large semi-major axes, eccentricities, and inclinations. Previous studies have determined that the Solar System's irregular satellites are extremely collisionally evolved populations today, having lost $\sim$99 per cent of their initial mass over the course of hundreds of Myr. Such an evolution implies that the irregular satellites must have produced a population of dusty collisional debris in the past, which is potentially observable due to the resulting reprocessing of stellar light. In this paper we examine the signatures of the debris discs produced by extrasolar analogues of this process. Radiation pressure, quantified by the parameter $\beta$, is the driving force behind the liberation of dust grains from the planetary Hill sphere, and results in the formation of circumstellar dust rings, even in the absence of an underlying belt of asteroids in the system. Our simulated discs reproduce many of the same features seen in some classes of observed debris discs, such as thin ring morphology, a large blowout size, and azimuthal symmetry. We compare our simulated discs' radial profiles to those of the narrow dust rings observed around Fomalhaut and HR 4796A, and show that they can broadly reproduce the observed radial distribution of dust., Comment: 19 pages, 17 figures
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- 2023
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27. Single-active-element demultiplexed multi-photon source
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Hansen, Lena M., Carosini, Lorenzo, Jehle, Lennart, Giorgino, Francesco, Houvenaghel, Romane, Vyvlecka, Michal, Loredo, Juan C., and Walther, Philip
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Quantum Physics - Abstract
Temporal-to-spatial demultiplexing routes non-simultaneous events of the same spatial mode to distinct output trajectories. This technique has now been widely adopted because it gives access to higher-number multi-photon states when exploiting solid-state quantum emitters. However, implementations so far have required an always-increasing number of active elements, rapidly facing resource constraints. Here, we propose and demonstrate a demultiplexing approach that utilizes only a single active element for routing to, in principle, an arbitrary number of outputs. We employ our device in combination with a high-efficiency quantum dot based single-photon source, and measure up to eight demultiplexed highly indistinguishable single photons. We discuss the practical limitations of our approach, and describe in which conditions it can be used to demultiplex, e.g., tens of outputs. Our results thus provides a path for the preparation of resource-efficient larger-scale multi-photon sources., Comment: 7 pages, 7 figures
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- 2023
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28. Urologic surveillance of persons with spinal cord injuries – a scoping review
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Bødker, Christian, Riisbøl, Maja F., Khan, Benjamin Y. A., Hansen, Rikke M., and Severinsen, Kaare E.
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- 2024
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29. Consequences of dynamically unstable moons in extrasolar systems
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Hansen, Bradley M. S.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Moons orbiting rocky exoplanets in compact orbits about other stars experience an accelerated tidal evolution, and can either merge with their parent planet or reach the limit of dynamical instability within a Hubble time. We review the parameter space over which moons become unbound, including the effects of atmospheric tides on the planetary spin. We find that such tides can change the final outcome from merger to escape, albeit over a limited parameter space. We also follow the further evolution of unbound moons, and demonstrate that the overwhelmingly most likely long-term outcome is that the unbound moon returns to collide with its original parent planet. The dust released by such a collision is estimated to reach optical depths approximately 0.001, exhibit characteristic temperatures of a few hundred degrees Kelvin, and last for a few thousand years. These properties make such events an attractive model for the emerging class of middle-aged main sequence stars that are observed to show transient clouds of warm dust. Furthermore, a late collision between a planet and a returning moon on a hyperbolic orbit may sterilise an otherwise habitable planet., Comment: to appear in Monthly Notices of the Royal Astronomical Society
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- 2022
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30. Host immune response mediates changes in cagA copy number and virulence potential of Helicobacter pylori
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Jang, Sungil, Hansen, Lori M, Su, Hanfu, Solnick, Jay V, and Cha, Jeong-Heon
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Microbiology ,Biological Sciences ,Emerging Infectious Diseases ,Infectious Diseases ,Digestive Diseases ,Genetics ,Cancer ,Digestive Diseases - (Peptic Ulcer) ,2.1 Biological and endogenous factors ,Aetiology ,Infection ,Animals ,Antigens ,Bacterial ,Bacterial Proteins ,DNA Copy Number Variations ,Gastrointestinal Microbiome ,Helicobacter Infections ,Helicobacter pylori ,Immunity ,Interleukin-10 ,Interleukin-8 ,Mice ,Virulence ,cagA ,cagY ,virulence ,immune response - Abstract
Helicobacter pylori is the major risk factor for gastric cancer. H. pylori harboring the type IV secretion system (T4SS) and its effector CagA encoded on the cag pathogenicity Island (cagPAI) increases the risk. H. pylori PMSS1 has a multi-cagA genotype, modulating cagA copy number dynamically from zero to four copies. To examine the effect of the immune response on cagA copy number change, we utilized a mouse model with different immune status. PMSS1 recovered from Rag1-/- mice, lacking functional T or B cells, retained more cagA copies. PMSS1 recovered from Il10-/- mice, showing intense inflammation, had fewer cagA copies compared to those recovered from wild-type mice. Moreover, cagA copy number of PMSS1 recovered from wild-type and Il10-/- mice was positively correlated with the capacity to induce IL-8 secretion at four weeks of infection. Since recombination in cagY influences T4SS function, including CagA translocation and IL-8 induction, we constructed a multiple linear regression model to predict H. pylori-induced IL-8 expression based on cagA copy number and cagY recombination status; H. pylori induces more IL-8 secretion when the strain has more cagA copies and intact cagY. This study shows that H. pylori PMSS1 in mice with less intense immune response possess higher cagA copy number than those infected in mice with more intense immune response and thus the multi-cagA genotype, along with cagY recombination, functions as an immune-sensitive regulator of H. pylori virulence.
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- 2022
31. When Do Stars Go BOOM?
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Richer, Harvey B., Cohen, Roger E., Correnti, Matteo, Caiazzo, Ilaria, Cummings, Jeffrey, Goudfrooij, Paul, Hansen, Bradley M. S., Heyl, Jeremy, Peeples, Molly, Kalirai, Jason, Sabbi, Elena, Tremblay, Pier-Emmanuel, and Williams, Benjamin
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
The maximum mass of a star that can produce a white dwarf (WD) is an important astrophysical quantity. One of the best approaches to establishing this limit is to search for WDs in young star clusters in which only massive stars have had time to evolve and where the mass of the progenitor can be established from the cooling time of the WD together with the age of the cluster. Searches in young Milky Way clusters have not thus far yielded WD members more massive than about 1.1$~M_{\odot}$, well below the Chandrasekhar mass of $1.38~M_{\odot}$, nor progenitors with masses in excess of about $6~M_{\odot}$. However, the hunt for potentially massive WDs that escaped their cluster environs is yielding interesting candidates. To expand the cluster sample further, we used HST to survey four young and massive star clusters in the Magellanic Clouds for bright WDs that could have evolved from stars as massive as 10$~M_{\odot}$. We located five potential WD candidates in the oldest of the four clusters examined, the first extragalactic single WDs thus far discovered. As these hot WDs are very faint at optical wavelengths, final confirmation will likely have to await spectroscopy with 30-metre class telescopes., Comment: 10 pages, 5 figures, accepted to the Astrophysical Journal Letters
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- 2022
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32. Modeling and explaining the growth patterns over time of country-specific website clickstream metrics
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Hansen, Jared M. and Wilson, Paul
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- 2023
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33. Unbound Close Stellar Encounters in the Solar Neighborhood
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Hansen, Bradley M. S.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
We present a catalog of unbound stellar pairs, within 100 pc of the Sun, that are undergoing close, hyperbolic, encounters. The data are drawn from the GAIA EDR3 catalogue, and the limiting factors are errors in the radial distance and unknown velocities along the line of sight. Such stellar pairs have been suggested (Hansen & Zuckerman 2021) to be possible events associated with the migration of technological civilisations between stars. As such, this sample may represent a finite set of targets for a SETI search based on this hypothesis. Our catalog contains a total of 132 close passage events, featuring stars from across the entire main sequence, with 16 pairs featuring at least one main sequence star of spectral type between K1 and F3. Many of these stars are also in binaries, so that we isolate eight single stars as the most likely candidates to search for an ongoing migration event -- HD 87978, HD 92577, HD 50669, HD 44006, HD 80790, LSPM J2126+5338, LSPM J0646+1829 and HD 192486. Amongst host stars of known planets, the stars GJ 433 and HR 858 are the best candidates., Comment: 25 pages, 10 figures+22 finding charts. to appear in AJ
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- 2021
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34. Accelerated epigenetic aging in newborns with Down syndrome
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Xu, Keren, Li, Shaobo, Muskens, Ivo S, Elliott, Natalina, Myint, Swe Swe, Pandey, Priyatama, Hansen, Helen M, Morimoto, Libby M, Kang, Alice Y, Ma, Xiaomei, Metayer, Catherine, Mueller, Beth A, Roberts, Irene, Walsh, Kyle M, Horvath, Steve, Wiemels, Joseph L, and de Smith, Adam J
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Biological Sciences ,Biomedical and Clinical Sciences ,Genetics ,Brain Disorders ,Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) ,Acquired Cognitive Impairment ,Alzheimer's Disease ,Intellectual and Developmental Disabilities (IDD) ,Neurodegenerative ,Neurosciences ,Aging ,Down Syndrome ,Pediatric ,Human Genome ,Dementia ,2.1 Biological and endogenous factors ,Congenital ,Good Health and Well Being ,Adult ,Aging ,Premature ,DNA Methylation ,Epigenesis ,Genetic ,Epigenomics ,Humans ,Infant ,Newborn ,Medical and Health Sciences ,Developmental Biology ,Biological sciences ,Biomedical and clinical sciences - Abstract
Accelerated aging is a hallmark of Down syndrome (DS), with adults experiencing early-onset Alzheimer's disease and premature aging of the skin, hair, and immune and endocrine systems. Accelerated epigenetic aging has been found in the blood and brain tissue of adults with DS but when premature aging in DS begins remains unknown. We investigated whether accelerated aging in DS is already detectable in blood at birth. We assessed the association between age acceleration and DS using five epigenetic clocks in 346 newborns with DS and 567 newborns without DS using Illumina MethylationEPIC DNA methylation array data. We compared two epigenetic aging clocks (DNAmSkinBloodClock and pan-tissue DNAmAge) and three epigenetic gestational age clocks (Haftorn, Knight, and Bohlin) between DS and non-DS newborns using linear regression adjusting for observed age, sex, batch, deconvoluted blood cell proportions, and genetic ancestry. Targeted sequencing of GATA1 was performed in a subset of 184 newborns with DS to identify somatic mutations associated with transient abnormal myelopoiesis. DS was significantly associated with increased DNAmSkinBloodClock (effect estimate = 0.2442, p
- Published
- 2022
35. The immunogenetics of viral antigen response is associated with subtype-specific glioma risk and survival
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Guerra, Geno, Kachuri, Linda, Wendt, George, Hansen, Helen M, Mack, Steven J, Molinaro, Annette M, Rice, Terri, Bracci, Paige, Wiencke, John K, Kasahara, Nori, Eckel-Passow, Jeanette E, Jenkins, Robert B, Wrensch, Margaret, and Francis, Stephen S
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Biomedical and Clinical Sciences ,Oncology and Carcinogenesis ,Immunology ,Rare Diseases ,Brain Cancer ,Prevention ,Brain Disorders ,Genetics ,Human Genome ,Neurosciences ,Biotechnology ,Clinical Research ,Infectious Diseases ,Cancer Genomics ,Cancer ,2.1 Biological and endogenous factors ,Infection ,Antigens ,Viral ,Epstein-Barr Virus Infections ,Glioma ,Herpesvirus 4 ,Human ,Humans ,Immunogenetics ,Multiple Sclerosis ,Epstein-Barr virus ,Merkel cell polyomavirus ,glioma ,human leukocyte antigen ,polygenic risk score ,Biological Sciences ,Medical and Health Sciences ,Genetics & Heredity ,Biological sciences ,Biomedical and clinical sciences ,Health sciences - Abstract
Glioma is a highly fatal cancer with prognostically significant molecular subtypes and few known risk factors. Multiple studies have implicated infections in glioma susceptibility, but evidence remains inconsistent. Genetic variants in the human leukocyte antigen (HLA) region modulate host response to infection and have been linked to glioma risk. In this study, we leveraged genetic predictors of antibody response to 12 viral antigens to investigate the relationship with glioma risk and survival. Genetic reactivity scores (GRSs) for each antigen were derived from genome-wide-significant (p
- Published
- 2022
36. Increasing Student Engagement Using 'Meme Based' Exercise Innovation
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Hansen, Jared M. and Wilson, Paul
- Abstract
The practice of "memes" -- taking an image from pop culture and adding humorous or inspiring text to it -- are an opportunity for marketing practice. We posit that memes also provide an innovative technique to help students become more engaged in marketing classes. We propose requiring students to submit one or more graded homework exercises using a meme (instead of the traditional slide deck or typed document file). Moreover, to create even more engagement and connection, we propose requiring the students to use a picture of the instructor teaching (from posted media choices by the instructor) as the background photo for the meme. Results of test usage in classes occurring in 2020 and 2021 indicate that this technique is helpful in students becoming more engaged in critical thinking toward class learning topics and class structure topics, this was especially evident when the meme course exercises leveraged competitive aspects such as student voting on them and prizes. Discussion of relevant technology adoption elements to consider in setting up exercise parameters are outlined.
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- 2023
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37. Interactions of Age and Blood Immune Factors and Noninvasive Prediction of Glioma Survival
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Molinaro, Annette M, Wiencke, John K, Warrier, Gayathri, Koestler, Devin C, Chunduru, Pranathi, Lee, Ji Yoon, Hansen, Helen M, Lee, Sean, Anguiano, Joaquin, Rice, Terri, Bracci, Paige M, McCoy, Lucie, Salas, Lucas A, Christensen, Brock C, Wrensch, Margaret, Kelsey, Karl T, Taylor, Jennie W, and Clarke, Jennifer L
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Biomedical and Clinical Sciences ,Oncology and Carcinogenesis ,Immunology ,Rare Diseases ,Brain Disorders ,Neurosciences ,Cancer ,Genetics ,Brain Cancer ,Good Health and Well Being ,Adult ,Brain Neoplasms ,Child ,Preschool ,Glioma ,Humans ,Immunologic Factors ,Isocitrate Dehydrogenase ,Mutation ,Prognosis ,Oncology & Carcinogenesis ,Oncology and carcinogenesis - Abstract
BackgroundTumor-based classification of human glioma portends patient prognosis, but considerable unexplained survival variability remains. Host factors (eg, age) also strongly influence survival times, partly reflecting a compromised immune system. How blood epigenetic measures of immune characteristics and age augment molecular classifications in glioma survival has not been investigated. We assess the prognostic impact of immune cell fractions and epigenetic age in archived blood across glioma molecular subtypes for the first time.MethodsWe evaluated immune cell fractions and epigenetic age in archived blood from the University of California San Francisco Adult Glioma Study, which included a training set of 197 patients with IDH-wild type, 1p19q intact, TERT wild type (IDH/1p19q/TERT-WT) glioma, an evaluation set of 350 patients with other subtypes of glioma, and 454 patients without glioma.ResultsIDH/1p19q/TERT-WT patients had lower lymphocyte fractions (CD4+ T, CD8+ T, natural killer, and B cells) and higher neutrophil fractions than people without glioma. Recursive partitioning analysis delineated 4 statistically significantly different survival groups for patients with IDH/1p19q/TERT-WT based on an interaction between chronological age and 2 blood immune factors, CD4+ T cells, and neutrophils. Median overall survival ranged from 0.76 years (95% confidence interval = 0.55-0.99) for the worst survival group (n = 28) to 9.72 years (95% confidence interval = 6.18 to not available) for the best (n = 33). The recursive partitioning analysis also statistically significantly delineated 4 risk groups in patients with other glioma subtypes.ConclusionsThe delineation of different survival groups in the training and evaluation sets based on an interaction between chronological age and blood immune characteristics suggests that common host immune factors among different glioma types may affect survival. The ability of DNA methylation-based markers of immune status to capture diverse, clinically relevant information may facilitate noninvasive, personalized patient evaluation in the neuro-oncology clinic.
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- 2022
38. Cross-beam energy transfer saturation by ion trapping-induced detuning
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Nguyen, K. L., Yin, L., Albright, B. J., Hansen, A. M., Froula, D. H., Turnbull, D., Follett, R. K., and Palastro, J. P.
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Physics - Plasma Physics ,High Energy Physics - Theory - Abstract
The performance of direct-drive inertial confinement fusion implosions relies critically on the coupling of laser energy to the target plasma. Cross-beam energy transfer (CBET), the resonant exchange of energy between intersecting laser beams mediated by ponderomotively driven ion-acoustic waves (IAW), inhibits this coupling by scattering light into unwanted directions. The variety of beam intersection angles and varying plasma conditions in an implosion results in IAWs with a range of phase velocities. Here we show that CBET saturates through a resonance detuning that depends on the IAW phase velocity and that results from trapping-induced modifications to the ion distribution functions. For smaller phase velocities, the modifications to the distribution functions can rapidly thermalize in the presence of mid-Z ions, leading to a blueshift in the resonant frequency. For larger phase velocities, the modifications can persist, leading to a redshift in the resonant frequency. Ultimately, these results may reveal pathways towards CBET mitigation and inform reduced models for radiation hydrodynamics codes to improve their predictive capability.
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- 2021
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39. Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling
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Salas, Lucas A, Zhang, Ze, Koestler, Devin C, Butler, Rondi A, Hansen, Helen M, Molinaro, Annette M, Wiencke, John K, Kelsey, Karl T, and Christensen, Brock C
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Biomedical and Clinical Sciences ,Immunology ,Immunotherapy ,Clinical Research ,Human Genome ,Genetics ,Immunization ,2.1 Biological and endogenous factors ,5.1 Pharmaceuticals ,Inflammatory and immune system ,Cancer ,Algorithms ,Basophils ,Blood ,CD4-Positive T-Lymphocytes ,CD8-Positive T-Lymphocytes ,CpG Islands ,DNA Methylation ,Epigenesis ,Genetic ,Flow Cytometry ,Humans ,Leukocyte Count ,Monocytes ,Neutrophils ,Oligonucleotide Array Sequence Analysis - Abstract
DNA methylation microarrays can be employed to interrogate cell-type composition in complex tissues. Here, we expand reference-based deconvolution of blood DNA methylation to include 12 leukocyte subtypes (neutrophils, eosinophils, basophils, monocytes, naïve and memory B cells, naïve and memory CD4 + and CD8 + T cells, natural killer, and T regulatory cells). Including derived variables, our method provides 56 immune profile variables. The IDOL (IDentifying Optimal Libraries) algorithm was used to identify libraries for deconvolution of DNA methylation data for current and previous platforms. The accuracy of deconvolution estimates obtained using our enhanced libraries was validated using artificial mixtures and whole-blood DNA methylation with known cellular composition from flow cytometry. We applied our libraries to deconvolve cancer, aging, and autoimmune disease datasets. In conclusion, these libraries enable a detailed representation of immune-cell profiles in blood using only DNA and facilitate a standardized, thorough investigation of immune profiles in human health and disease.
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- 2022
40. Student Perception and Affinity: Establishment of an Institutional Framework for the Examination of Underrepresented Programs Such as Agriculture in Honors
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Kutzke, Kayla L., Nold, Rosemarie A., Gonda, Michael G., Hansen, Alecia M., and Bott-Knutson, Rebecca C.
- Abstract
This (2019) study assesses student perceptions of an honors college relative to other colleges in an institutional framework. Disproportionately low enrollments in honors from specific majors (particularly those in the College of Agriculture, Food, and Environmental Sciences) prompt researchers to investigate the culture of honors, perceived curricular demands, and the relationship of honors to other colleges and the students they serve. Researchers survey honors and non-honors students (n = 259) across disciplines (n = 59) representing all academic colleges across campus. Data suggest that while a majority of students affirm their abilities to complete the honors curriculum and perceive honors study to be beneficial, fewer than half (0.4) of respondents report actively pursuing honors distinction. Researchers identify three major reasons: perceived lack of time, misunderstanding of requirements, and aversion to independent study. Respondents also indicate that their interests in honors might increase if connections between honors and their majors/colleges were more apparent. The authors conclude that student-centered ideas for creating value in honors are essential for future efforts in programming and recruitment.
- Published
- 2020
41. The Stationary Points of the Hierarchical Three Body Problem
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Hansen, Bradley M. S. and Naoz, Smadar
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Astrophysics - Earth and Planetary Astrophysics ,Nonlinear Sciences - Chaotic Dynamics - Abstract
We study the stationary points of the hierarchical three body problem in the planetary limit (m_2, m_3 << m_1) at both the quadrupole and octupole orders. We demonstrate that the extension to octupole order preserves the principal stationary points of the quadrupole solution in the limit of small outer eccentricity e_2 but that new families of stable fixed points occur in both prograde and retrograde cases. The most important new equilibria are those that branch off from the quadrupolar solutions and extend to large e_2. The apsidal alignment of these families is a function of mass and inner planet eccentricity, and is determined by the relative directions of precession of omega_1 and omega_2 at the quadrupole level. These new equilibria are also the most resilient to the destabilizing effects of relativistic precession. We find additional equilibria that enable libration of the inner planet argument of pericentre in the limit of radial orbits and recover the non-linear analogue of the Laplace-Lagrange solutions in the coplanar limit. Finally, we show that the chaotic diffusion and orbital flips identified with the Eccentric Kozai Lidov mechanism and its variants can be understood in terms of the stationary points discussed here., Comment: 27 pages, 36 figures
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- 2020
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42. Data-Driven Power Electronic Converter Modeling for Low Inertia Power System Dynamic Studies
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Guruwacharya, Nischal, Bhujel, Niranjan, Tamrakar, Ujjwol, Rauniyar, Manisha, Subedi, Sunil, Berg, Sterling E., Hansen, Timothy M., and Tonkoski, Reinaldo
- Subjects
Electrical Engineering and Systems Science - Systems and Control - Abstract
A significant amount of converter-based generation is being integrated into the bulk electric power grid to fulfill the future electric demand through renewable energy sources, such as wind and photovoltaic. The dynamics of converter systems in the overall stability of the power system can no longer be neglected as in the past. Numerous efforts have been made in the literature to derive detailed dynamic models, but using detailed models becomes complicated and computationally prohibitive in large system level studies. In this paper, we use a data-driven, black-box approach to model the dynamics of a power electronic converter. System identification tools are used to identify the dynamic models, while a power amplifier controlled by a real-time digital simulator is used to perturb and control the converter. A set of linear dynamic models for the converter are derived, which can be employed for system level studies of converter-dominated electric grids.
- Published
- 2020
43. Askaryan radiation from neutrino-induced showers in ice
- Author
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Alvarez-Muñiz, Jaime, Hansen, P. M., Romero-Wolf, Andrés, and Zas, Enrique
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We present a semi-analytical method for the calculation of coherent Askaryan radiation in showers induced by neutrinos of any flavor in ice. We compare our results with those of a full Monte Carlo simulation based on the ZHAireS code. This approach is able to reproduce the vector potential and hence electric field at any experimentally relevant observer position in the time domain. This work extends published results only valid for electron-induced showers. We establish the validity of the semi-analytical calculation of the radio signal produced by all types of neutrino-induced showers in ice. The method is computationally efficient and only requires as inputs the longitudinal charge excess profile of the showers and a parameterization of the vector potential in the far-field region of the shower at the Cherenkov angle that we also provide. Our methodology avoids tracking the contributions to the electric field from millions of particles every time the radio pulse has to be calculated at a given observer position. These results can be readily used in the interpretation of the data taken by experiments, and in the planning and design of future initiatives based on the radio technique in ice., Comment: 18 pages, 11 figures. Accepted in Phys. Rev. D
- Published
- 2020
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44. Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia
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Tubío-Santamaría, Nuria, Jayavelu, Ashok Kumar, Schnoeder, Tina M., Eifert, Theresa, Hsu, Chen-Jen, Perner, Florian, Zhang, Qirui, Wenge, Daniela V., Hansen, Fynn M., Kirkpatrick, Joanna M., Jyotsana, Nidhi, Lane, Steven W., von Eyss, Björn, Deshpande, Aniruddha J., Kühn, Michael W. M., Schwaller, Juerg, Cammann, Clemens, Seifert, Ulrike, Ebstein, Frédéric, Krüger, Elke, Hochhaus, Andreas, Heuser, Michael, Ori, Alessandro, Mann, Matthias, Armstrong, Scott A., and Heidel, Florian H.
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- 2023
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45. COVID-19 severity scale for claims data research
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Krause, Trudy Millard, Greenberg, Raymond, Ghosh, Lopita, Wozny, Joseph S., Hansen, Regina M., and Schaefer, Caroline
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- 2023
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46. The Scientific Legacy of NASA’s Operation IceBridge
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MacGregor, Joseph A, Boisvert, Linette N, Medley, Brooke, Petty, Alek A, Harbeck, Jeremy P, Bell, Robin E, Blair, J Bryan, Blanchard‐Wrigglesworth, Edward, Buckley, Ellen M, Christoffersen, Michael S, Cochran, James R, Csathó, Beáta M, Marco, Eugenia L, Dominguez, RoseAnne T, Fahnestock, Mark A, Farrell, Sinéad L, Gogineni, S Prasad, Greenbaum, Jamin S, Hansen, Christy M, Hofton, Michelle A, Holt, John W, Jezek, Kenneth C, Koenig, Lora S, Kurtz, Nathan T, Kwok, Ronald, Larsen, Christopher F, Leuschen, Carlton J, Locke, Caitlin D, Manizade, Serdar S, Martin, Seelye, Neumann, Thomas A, Nowicki, Sophie MJ, Paden, John D, Richter‐Menge, Jacqueline A, Rignot, Eric J, Rodríguez‐Morales, Fernando, Siegfried, Matthew R, Smith, Benjamin E, Sonntag, John G, Studinger, Michael, Tinto, Kirsty J, Truffer, Martin, Wagner, Thomas P, Woods, John E, Young, Duncan A, and Yungel, James K
- Subjects
Climate Action ,Physical Sciences ,Earth Sciences ,Engineering ,Meteorology & Atmospheric Sciences - Abstract
The National Aeronautics and Space Administration (NASA)’s Operation IceBridge (OIB) was a 13-year (2009–2021) airborne mission to survey land and sea ice across the Arctic, Antarctic, and Alaska. Here, we review OIB’s goals, instruments, campaigns, key scientific results, and implications for future investigations of the cryosphere. OIB’s primary goal was to use airborne laser altimetry to bridge the gap in fine-resolution elevation measurements of ice from space between the conclusion of NASA’s Ice, Cloud, and land Elevation Satellite (ICESat; 2003–2009) and its follow-on, ICESat-2 (launched 2018). Additional scientific requirements were intended to contextualize observed elevation changes using a multisensor suite of radar sounders, gravimeters, magnetometers, and cameras. Using 15 different aircraft, OIB conducted 968 science flights, of which 42% were repeat surveys of land ice, 42% were surveys of previously unmapped terrain across the Greenland and Antarctic ice sheets, Arctic ice caps, and Alaskan glaciers, and 16% were surveys of sea ice. The combination of an expansive instrument suite and breadth of surveys enabled numerous fundamental advances in our understanding of the Earth’s cryosphere. For land ice, OIB dramatically improved knowledge of interannual outlet-glacier variability, ice-sheet, and outlet-glacier thicknesses, snowfall rates on ice sheets, fjord and sub-ice-shelf bathymetry, and ice-sheet hydrology. Unanticipated discoveries included a reliable method for constraining the thickness within difficult-to-sound incised troughs beneath ice sheets, the extent of the firn aquifer within the Greenland Ice Sheet, the vulnerability of many Greenland and Antarctic outlet glaciers to ocean-driven melting at their grounding zones, and the dominance of surface-melt-driven mass loss of Alaskan glaciers. For sea ice, OIB significantly advanced our understanding of spatiotemporal variability in sea ice freeboard and its snow cover, especially through combined analysis of fine-resolution altimetry, visible imagery, and snow radar measurements of the overlying snow thickness. Such analyses led to the unanticipated discovery of an interdecadal decrease in snow thickness on Arctic sea ice and numerous opportunities to validate sea ice freeboards from satellite radar altimetry. While many of its data sets have yet to be fully explored, OIB’s scientific legacy has already demonstrated the value of sustained investment in reliable airborne platforms, airborne instrument development, interagency and international collaboration, and open and rapid data access to advance our understanding of Earth’s remote polar regions and their role in the Earth system.
- Published
- 2021
47. The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis.
- Author
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Muskens, Ivo S, Li, Shaobo, Jackson, Thomas, Elliot, Natalina, Hansen, Helen M, Myint, Swe Swe, Pandey, Priyatama, Schraw, Jeremy M, Roy, Ritu, Anguiano, Joaquin, Goudevenou, Katerina, Siegmund, Kimberly D, Lupo, Philip J, de Bruijn, Marella FTR, Walsh, Kyle M, Vyas, Paresh, Ma, Xiaomei, Roy, Anindita, Roberts, Irene, Wiemels, Joseph L, and de Smith, Adam J
- Subjects
Liver ,Hematopoietic Stem Cells ,Fetus ,Humans ,Down Syndrome ,Case-Control Studies ,Hematopoiesis ,DNA Methylation ,Epigenesis ,Genetic ,CpG Islands ,Genome ,Human ,Infant ,Newborn ,Female ,Male ,Core Binding Factor Alpha 2 Subunit ,GATA1 Transcription Factor ,Proto-Oncogene Protein c-fli-1 ,Promoter Regions ,Genetic ,Genome-Wide Association Study ,Epigenesis ,Genetic ,Genome ,Human ,Infant ,Newborn ,Promoter Regions - Abstract
Down syndrome is associated with genome-wide perturbation of gene expression, which may be mediated by epigenetic changes. We perform an epigenome-wide association study on neonatal bloodspots comparing 196 newborns with Down syndrome and 439 newborns without Down syndrome, adjusting for cell-type heterogeneity, which identifies 652 epigenome-wide significant CpGs (P
- Published
- 2021
48. Genetic Considerations in the Locoregional Management of Breast Cancer: a Review of Current Evidence
- Author
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Bushara, Omar and Hansen, Nora M.
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- 2023
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49. Close-in giant-planet formation via in-situ gas accretion and their natal disk properties
- Author
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Hasegawa, Yasuhiro, Yu, Tze Yeung Mathew, and Hansen, Bradley M. S.
- Subjects
Astrophysics - Earth and Planetary Astrophysics - Abstract
The origin of close-in Jovian planets is still elusive. We examine the in-situ gas accretion scenario as a formation mechanism of these planets. We reconstruct natal disk properties from the occurrence rate distribution of close-in giant planets, under the assumption that the occurrence rate may reflect the gas accretion efficiency onto cores of these planets. We find that the resulting gas surface density profile becomes an increasing function of the distance from the central star with some structure at $r \simeq 0.1$ au. This profile is quite different from the standard minimum-mass solar nebula model, while our profile leads to better reproduction of the population of observed close-in super-Earths based on previous studies. We compute the resulting magnetic field profiles and find that our profiles can be fitted by stellar dipole fields ($\propto r^{-3}$) in the vicinity of the central star and large-scale fields ($\propto r^{-2}$) at the inner disk regions, either if the isothermal assumption breaks down or if nonideal MHD effects become important. For both cases, the transition between these two profiles occurs at $r \simeq 0.1$ au, which corresponds to the period valley of giant exoplanets. Our work provides an opportunity to test the in-situ gas accretion scenario against disk quantities, which may constrain the gas distribution of the minimum-mass {\it extra}solar nebula., Comment: 5 pages, 3 figures, accepted for publication in A&A Letters
- Published
- 2019
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50. The Chaotic Nature of TRAPPIST-1 Planetary Spin States
- Author
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Vinson, Alec M., Tamayo, Daniel, and Hansen, Brad M. S.
- Subjects
Astrophysics - Earth and Planetary Astrophysics - Abstract
The TRAPPIST-1 system has 7 known terrestrial planets arranged compactly in a mean motion resonant chain around an ultra-cool central star, some within the estimated habitable zone. Given their short orbital periods of just a few days, it is often presumed that the planets are tidally locked such that the spin rate is equal to that of the orbital mean motion. However, the compact, and resonant, nature of the system implies that there can be significant variations in the mean motion of these planets due to their mutual interactions. We show that such fluctuations can then have significant effects on the spin states of these planets. In this paper, we analyze, using detailed numerical simulations, the mean motion histories of the three planets that are thought to lie within or close to the habitable zone of the system: planets d, e, and f. We demonstrate that, depending on the strength of the mutual interactions within the system, these planets can be pushed into spin states which are effectively non-synchronous. We find that it can produce significant libration of the spin state, if not complete circulation in the frame co-rotating with the orbit. We also show that these spin states are likely to be unable to sustain long-term stability, with many of our simulations suggesting that the spin evolves, under the influence of tidal synchronization forces, into quasi-stable attractor states, which last on timescales of thousands of years., Comment: 9 pages, 11 figures. Added new results for best-fit of real TRAPPIST-1 system, added clarifications, fixed typos, and added new references. Accepted to MNRAS
- Published
- 2019
- Full Text
- View/download PDF
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