25 results on '"Hang T T, Nguyen"'
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2. EFL students’ perspectives on the employment of language learning strategies
- Author
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Tham My Duong and Hang T. T. Nguyen
- Subjects
Language learning strategies ,frequency ,high school students ,Vietnamese EFL context ,Education ,English language ,PE1-3729 - Abstract
It is widely acknowledged that language learning strategies (LLSs) are beneficial to learners’ academic achievements, learner autonomy and motivation; however, it is indicated that Vietnamese students, particularly high school students have found it hard to employ LLSs. This paper aims at exploring language learning strategies used by high school students and underlying reasons at a high school located in Ho Chi Minh City. The study involved 238 EFL high school students in responding to a closed-ended questionnaire and twenty of them in answering the semi-structured interview questions. The quantitative data collected from the questionnaire were processed by SPSS version 25.0 in terms of descriptive statistics, and the qualitative data were analyzed by the content-based approach. The results of the study indicated the EFL high school students’ moderate use of LLSs. Remarkably, metacognitive strategies were the most commonly used category, compared to memory strategies – the least employed category. The findings may serve as a guideline for EFL teachers on facilitating high school students’ English language learning. It is also hoped that the results of this study may contribute to the literature about English language learning strategies in EFL contexts.
- Published
- 2021
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- View/download PDF
3. Corrigendum: The Hsp90 Inhibitor, Monorden, Is a Promising Lead Compound for the Development of Novel Fungicides
- Author
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Hang T. T. Nguyen, Soyoung Choi, Soonok Kim, Ju-Hee Lee, Ae Ran Park, Nan Hee Yu, Hyeokjun Yoon, Chang-Hwan Bae, Joo Hong Yeo, Gyung Ja Choi, Hokyoung Son, and Jin-Cheol Kim
- Subjects
antifungal activity ,disease control efficacy ,Hsp90 ,mode of action ,monorden ,Plant culture ,SB1-1110 - Published
- 2020
- Full Text
- View/download PDF
4. The Hsp90 Inhibitor, Monorden, Is a Promising Lead Compound for the Development of Novel Fungicides
- Author
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Hang T. T. Nguyen, Soyoung Choi, Soonok Kim, Ju-Hee Lee, Ae Ran Park, Nan Hee Yu, Hyeokjun Yoon, Chang-Hwan Bae, Joo Hong Yeo, Gyung Ja Choi, Hokyoung Son, and Jin-Cheol Kim
- Subjects
antifungal activity ,disease control efficacy ,Hsp90 ,mode of action ,monorden ,Plant culture ,SB1-1110 - Abstract
Endophytic fungi are great resources for the identification of useful natural products such as antimicrobial agents. In this study, we performed the antifungal screening of various plant endophytic fungi against the dollar spot pathogen Sclerotinia homoeocarpa and finally selected Humicola sp. JS-0112 as a potential biocontrol agent. The bioactive compound produced by the strain JS-0112 was identified as monorden known as an inhibitor of heat shock protein 90 (Hsp90). Monorden exhibited strong antagonistic activity against most tested plant pathogenic fungi particularly against tree pathogens and oomycetes with the minimum inhibitory concentration values less than 2.5 μg mL–1. Extensive in planta assays revealed that monorden effectively suppressed the development of several important plant diseases such as rice blast, rice sheath blight, wheat leaf rust, creeping bentgrass dollar spot, and cucumber damping-off. Especially, it showed much stronger disease control efficacy against cucumber damping-off than a synthetic fungicide chlorothalonil. Subsequent molecular genetic analysis of fission yeast and Fusarium graminearum suggested that Hsp90 is a major inhibitory target of monorden, and sequence variation among fungal Hsp90 is a determinant for the dissimilar monorden sensitivity of fungi. This is the first report dealing with the disease control efficacy and antifungal mechanism of monorden against fungal plant diseases and we believe that monorden can be used as a lead molecule for developing novel fungicides with new action mechanism for the control of plant diseases caused by fungi and oomycetes.
- Published
- 2020
- Full Text
- View/download PDF
5. Efficient and recyclable Nd3+-doped CoFe2O4 for boosted visible light-driven photocatalytic degradation of Rhodamine B dye
- Author
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Loan T. T. Nguyen, Hang T. T. Nguyen, Lan T. H. Nguyen, Anh T. T. Duong, Hai Q. Nguyen, Viet T. M. Ngo, Nhuong V. Vu, Duyen Thi Cam Nguyen, and Thuan Van Tran
- Subjects
General Chemical Engineering ,General Chemistry - Abstract
Doping of neodymium ions into CoFe2O4 nanoparticles significantly boosted the photocatalytic activity of CoNdxFe2−xO4 for the degradation of Rhodamine B dye. Up to 94.7% of dye was degraded under CoNd0.05Fe1.95O4/H2O2/visible-light system.
- Published
- 2023
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- View/download PDF
6. The future of molecular ecology in Aotearoa New Zealand: an early career perspective
- Author
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Libby Liggins, Vanessa Arranz, Heather E. Braid, David Carmelet-Rescan, Joane Elleouet, Ekaterina Egorova, Michael R. Gemmell, Simon F. K. Hills, Lyndsey P. Holland, Emily M. Koot, Alexandra Lischka, Kimberley H. Maxwell, Laura J. McCartney, Hang T. T. Nguyen, Cory Noble, Pamela Olmedo Rojas, Elahe Parvizi, William S. Pearman, Jenny Ann N. Sweatman, Te Rangitākuku Kaihoro, Kerry Walton, J. David Aguirre, and Lucy C. Stewart
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Multidisciplinary - Published
- 2022
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7. A Facile Synthesis, Characterization, and Photocatalytic Activity of Magnesium Ferrite Nanoparticles via the Solution Combustion Method
- Author
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Loan T. T. Nguyen, Lan T. H. Nguyen, Nhuong Chu Manh, Dung Nguyen Quoc, Hai Nguyen Quang, Hang T. T. Nguyen, Duy Chinh Nguyen, and Long Giang Bach
- Subjects
Chemistry ,QD1-999 - Abstract
In this study, we adopted the solution combustion method to synthesize magnesium ferrite (MgFe2O4) using urea as the fuel. Various techniques including TGA, XRD, SEM, TEM, FTIR, UV-Vis DRS, and EDS were employed to characterize the synthesized MgFe2O4 nanoparticles. The XRD analysis revealed that single-phase MgFe2O4 was formed at a calcination temperature of at 500–600°C for 3 hours in the absence of an intermediate phase. TEM analysis also revealed the formation of monodisperse magnesium ferrite nanoparticles, averaged at 30 nm in size. The photocatalytic activity of the synthesized MgFe2O4 nanoparticles against methylene blue dye under visible light was investigated, showing the efficiency of 89.73% after 240 minutes of light irradiation with the presence of H2O2.
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- 2019
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8. Coralline photosynthetic physiology across a steep light gradient
- Author
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Hang T. T. Nguyen, Daniel W. Pritchard, Matthew J. Desmond, and Christopher D. Hepburn
- Subjects
Cell Biology ,Plant Science ,General Medicine ,Biochemistry - Published
- 2022
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9. Dynamic capabilities in tourism businesses: antecedents and outcomes
- Author
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Hang T. T. Nguyen, Hanh Song Thi Pham, Susan Freeman, Nguyen, Hang TT, Pham, Hanh Song Thi, and Freeman, Susan
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tourism services ,micro-foundations of dynamic capabilities ,dynamic capabilities view ,General Business, Management and Accounting ,emerging economies - Abstract
This paper examines dynamic capabilities as a second-order construct and the antecedents and outcomes of dynamic capabilities. Analyzing data collected from 242 tourism firms in Vietnam, this paper finds a positive influence of firms’ human capital, organizational learning, environmental dynamism, and digital marketing on the dynamic capabilities. Dynamic capabilities have a significant and positive impact on these firms’ competitive advantage. The paper contributes to ongoing efforts to measure dynamic capabilities and explore the micro-foundations of dynamic capabilities.
- Published
- 2023
10. Toward enhanced visible-light photocatalytic dye degradation and reusability of La
- Author
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Loan T T, Nguyen, Hang T T, Nguyen, Lan T H, Nguyen, Anh T T, Duong, Hai Q, Nguyen, Nguyen D, Bui, Viet T M, Ngo, Duyen Thi Cam, Nguyen, and Thuan Van, Tran
- Abstract
The present work focused on the synthesis of novel ZnLa
- Published
- 2022
11. Nitrogen and phosphorus ecophysiology of coralline algae
- Author
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Hang T. T. Nguyen, Daniel W. Pritchard, and Christopher D. Hepburn
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0106 biological sciences ,geography ,geography.geographical_feature_category ,biology ,010604 marine biology & hydrobiology ,Phosphorus ,Coralline algae ,chemistry.chemical_element ,Plant Science ,Aquatic Science ,biology.organism_classification ,01 natural sciences ,Kelp forest ,chemistry.chemical_compound ,Nutrient ,chemistry ,Nitrate ,Botany ,Ammonium ,Crustose ,Reef ,010606 plant biology & botany - Abstract
The characteristics of nutrient uptake in macroalgae are generally well known but surprisingly little is known about nutrient uptake in coralline algae despite their ecological importance and extensive depth distribution. This study provides the first information on nitrate, ammonium and phosphate storage and uptake by articulated and crustose coralline algae that are dominant features of temperate subtidal rocky reefs. A comparison was made between an articulated coralline alga, Arthrocardia sp. in the Corallinales and crustose coralline spp. within the Hapalidiales. Seawater nutrient concentration and nutrient storage by coralline algae were monitored between June 2016 and November 2017 in a kelp forest in southern New Zealand. Time-course nutrient depletion experiments were conducted to determine appropriate incubation times for multiple-flask experiments and evaluate maximal uptake of nitrate, ammonium, and phosphate over time in winter and summer. The uptake of ammonium exhibited a saturable kinetics with Vmax of Arthrocardia sp. (2.07 ± 0.32 μmol gDW−1 h−1) significantly higher than that of crustose coralline spp. (0.58 ± 0.17 μmol gDW−1 h−1). A linear relationship with concentration was observed in nitrate and phosphate uptake by both coralline algae. Ammonium was considered a preferred nitrogen source for these corallines compared with nitrate in both summer and winter. Morphological difference is suggested to be an important factor resulting in the difference in nitrogen and phosphorus uptake rates and kinetic parameters of these corallines. Further research is required to understand if these differences are general attributes of the functional ecology of crustose and articulated corallines.
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- 2020
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12. Graphene layer of hybrid graphene/hexagonal boron nitride model upon heating
- Author
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Hang T. T. Nguyen
- Subjects
Materials science ,Coordination number ,Energy Engineering and Power Technology ,Hexagonal boron nitride ,02 engineering and technology ,010402 general chemistry ,Ring (chemistry) ,01 natural sciences ,law.invention ,Inorganic Chemistry ,Molecular dynamics ,law ,Physics::Atomic and Molecular Clusters ,Materials Chemistry ,Cluster (physics) ,Renewable Energy, Sustainability and the Environment ,Graphene ,Process Chemistry and Technology ,Organic Chemistry ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Zigzag ,Chemical physics ,Ceramics and Composites ,0210 nano-technology ,Layer (electronics) - Abstract
Hybrid graphene/h-BN model is studied via molecular dynamics simulation to observe the evolution of graphene layer upon heating. Model containing 20,064 atoms is heated up from 50 to 8000 K via Tersoff and Lennard–Jones potentials. Various thermodynamic quantities, structural characteristics, and the occurrence of liquid-like atoms are studied. The Lindemann criterion for 2D case is calculated and used to observe the appearance of liquid-like atoms. The atomic mechanism of structural evolution upon heating is analyzed on the basis of the occurrence/growth of liquid-like atoms, the formation of clusters, the coordination number, and the ring statistics. The liquid-like atoms tend to form clusters and the largest cluster increases slightly in order to form a single largest cluster of liquid-like atoms. The other models such as free-standing graphene, zigzag GNR, and armchair GNR are also presented to have an entire picture about the evolution of graphene upon heating in different models. Note that the largest clusters of free-standing graphene as well as zigzag GNR, and armchair GNR tend to decrease to form a ring-like 2D liquid carbon.
- Published
- 2019
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13. Coralline photosynthetic physiology across a steep light gradient
- Author
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Hang T T, Nguyen, Daniel W, Pritchard, Matthew J, Desmond, and Christopher D, Hepburn
- Subjects
Kelp ,Light ,Rhodophyta ,Water ,Photosynthesis ,Ecosystem - Abstract
Coralline algae (CA) are globally distributed and fulfil many important roles within coastal ecosystems. In this study, photosynthetically active radiation (PAR) measured for 616 days at 2 and 10 m in a temperate subtidal kelp forest in southern New Zealand provided context to photosynthesis vs. irradiance relationships for, and pigment concentrations of, an articulated coralline alga, Arthrocardia sp. and a crustose coralline species assemblage within the Hapalidiales order. The maximum photosynthetic rate P
- Published
- 2021
14. Enhanced Photocatalytic Activity of Spherical Nd
- Author
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Hang T. T. Nguyen, Tan Van Lam, Lan T. H. Nguyen, Thuan Van Tran, Duyen Thi Cam Nguyen, Thieng H. Le, Loan T.T. Nguyen, Hai Q. Nguyen, Ngan T. K. Tran, Nguyen D. Bui, and Thanh Tung Pham
- Subjects
Technology ,Materials science ,Rhodamine B ,Nanoparticle ,neodymium-doping ,zinc ferrite ,Article ,Catalysis ,chemistry.chemical_compound ,photo-Fenton ,General Materials Science ,Microscopy ,QC120-168.85 ,QH201-278.5 ,Doping ,Engineering (General). Civil engineering (General) ,Nanocrystalline material ,TK1-9971 ,Zinc ferrite ,Descriptive and experimental mechanics ,chemistry ,Photocatalysis ,Ferrite (magnet) ,Electrical engineering. Electronics. Nuclear engineering ,TA1-2040 ,Nuclear chemistry - Abstract
In this study, nanocrystalline ZnNdxFe2−xO4 ferrites with x = 0.0, 0.01, 0.03 and 0.05 were fabricated and used as a catalyst for dye removal potential. The effect of Nd3+ ions substitution on the structural, optical and photo-Fenton activity of ZnNdxFe2−xO4 has been investigated. The addition of Nd3+ ions caused a decrease in the grain size of ferrites, the reduction of the optical bandgap energies and thus could be well exploited for the catalytic study. The photocatalytic activity of the ferrite samples was evaluated by the degradation of Rhodamine B (RhB) in the presence of H2O2 under visible light radiation. The results indicated that the ZnNdxFe2−xO4 samples exhibited higher removal efficiencies than the pure ZnFe2O4 ferrites. The highest degradation efficiency was 98.00%, attained after 210 min using the ZnNd0.03Fe1.97O4 sample. The enhanced photocatalytic activity of the ZnFe2O4 doped with Nd3+ is explained due to the efficient separation mechanism of photoinduced electron and holes. The effect of various factors (H2O2 oxidant concentration and catalyst loading) on the degradation of RhB dye was clarified.
- Published
- 2021
15. Evolution of the Graphene Layer in Hybrid Graphene/Silicon Carbide Heterostructures upon Heating
- Author
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Hang T. T. Nguyen and Duong Thi Nhu Tranh
- Subjects
010302 applied physics ,Materials science ,Graphene ,Heterojunction ,02 engineering and technology ,Atmospheric temperature range ,021001 nanoscience & nanotechnology ,01 natural sciences ,Molecular physics ,Atomic and Molecular Physics, and Optics ,law.invention ,chemistry.chemical_compound ,Molecular dynamics ,chemistry ,law ,0103 physical sciences ,Physics::Atomic and Molecular Clusters ,Cluster (physics) ,Melting point ,Silicon carbide ,Graphite ,0210 nano-technology - Abstract
The hybrid graphene/SiC model is studied via molecular dynamics simulation to observe the evolution of the graphene layer upon heating. A two-layer model containing 10,000 graphene atoms and 7000 SiC atoms is heated from 50 K to 6000 K via Tersoff and Lennard-Jones potentials. The melting point zone is defined as the temperature range from 4400 K to 4600 K, which is close to the melting zone of graphite in an experiment. The Lindemann criterion for the 2D case is calculated and used to observe the appearance of liquid-like atoms. The evolution upon heating is analyzed on the basis of the occurrence/growth of liquid-like atoms, the radial distribution functions, and the formation of clusters. The liquid-like atoms tend to form clusters, and the largest cluster increases in size slightly to form a single largest cluster of liquid-like atoms.
- Published
- 2021
- Full Text
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16. Structural evolution of free-standing 2D silicon carbide upon heating
- Author
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Tue Minh Le Nguyen, Vo Van Hoang, and Hang T. T. Nguyen
- Subjects
Materials science ,Coordination number ,Thermodynamics ,02 engineering and technology ,Solid like ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Ring (chemistry) ,01 natural sciences ,Structural evolution ,Heat capacity ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,Molecular dynamics ,chemistry.chemical_compound ,chemistry ,Silicon carbide ,Melting point ,0210 nano-technology - Abstract
Two-dimensional Silicon Carbide (2D SiC) model is studied via molecular dynamics simulation to observe the structural evolution upon heating. A model contains 11040 atoms interacting via Vashishta potentials. The model is heated up from 50 K to 4500 K in order to observe the changes in structures during heating process. The melting point of free-standing 2D SiC is defined to be around 4050 K by temperature dependence of the heat capacity. The Lindemann criterion for 2D case is calculated and used to classify the behaviors of the liquid like and solid like atoms. The atomic mechanism of structural evolution upon heating is analyzed based on the occurrence/growth of liquid like atoms the average coordination number the ring statistics as well as the angular distributions.
- Published
- 2020
- Full Text
- View/download PDF
17. The Hsp90 Inhibitor, Monorden, Is a Promising Lead Compound for the Development of Novel Fungicides
- Author
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Joo Hong Yeo, Soonok Kim, Ju-Hee Lee, Chang-Hwan Bae, Gyung Ja Choi, Hang T. T. Nguyen, Hokyoung Son, Hyeokjun Yoon, Ae Ran Park, Nan Hee Yu, Jin-Cheol Kim, and Soyoung Choi
- Subjects
Fusarium ,Dollar spot ,Hsp90 ,Plant Science ,Biology ,lcsh:Plant culture ,Plant use of endophytic fungi in defense ,Microbiology ,03 medical and health sciences ,chemistry.chemical_compound ,Wheat leaf rust ,mode of action ,lcsh:SB1-1110 ,Original Research ,030304 developmental biology ,0303 health sciences ,Chlorothalonil ,030306 microbiology ,fungi ,antifungal activity ,Correction ,food and beverages ,Antimicrobial ,biology.organism_classification ,monorden ,Bioactive compound ,disease control efficacy ,Fungicide ,chemistry - Abstract
Endophytic fungi are great resources for the identification of useful natural products such as antimicrobial agents. In this study, we performed the antifungal screening of various plant endophytic fungi against the dollar spot pathogen Sclerotinia homoeocarpa and finally selected Humicola sp. JS-0112 as a potential biocontrol agent. The bioactive compound produced by the strain JS-0112 was identified as monorden known as an inhibitor of heat shock protein 90 (Hsp90). Monorden exhibited strong antagonistic activity against most tested plant pathogenic fungi particularly against tree pathogens and oomycetes with the minimum inhibitory concentration values less than 2.5 μg mL–1. Extensive in planta assays revealed that monorden effectively suppressed the development of several important plant diseases such as rice blast, rice sheath blight, wheat leaf rust, creeping bentgrass dollar spot, and cucumber damping-off. Especially, it showed much stronger disease control efficacy against cucumber damping-off than a synthetic fungicide chlorothalonil. Subsequent molecular genetic analysis of fission yeast and Fusarium graminearum suggested that Hsp90 is a major inhibitory target of monorden, and sequence variation among fungal Hsp90 is a determinant for the dissimilar monorden sensitivity of fungi. This is the first report dealing with the disease control efficacy and antifungal mechanism of monorden against fungal plant diseases and we believe that monorden can be used as a lead molecule for developing novel fungicides with new action mechanism for the control of plant diseases caused by fungi and oomycetes.
- Published
- 2020
- Full Text
- View/download PDF
18. On the Cerenkov effect and non-classical states of electromagnetic vacuum: from classical pattern to quantum approach
- Author
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Mikhail E. Semenov, Hang T. T. Nguyen, Alexander F. Klinskikh, and Peter A. Meleshenko
- Subjects
Electromagnetic field ,Physics ,Field (physics) ,010308 nuclear & particles physics ,General Physics and Astronomy ,Electron ,01 natural sciences ,Charged particle ,Quantum electrodynamics ,0103 physical sciences ,Classical electromagnetism ,010306 general physics ,Quantum ,Cherenkov radiation ,Squeezed coherent state - Abstract
In this paper, using the quantum approach, we consider the Cerenkov radiation in the case in which an electron moves in the background of the non-classical state of the electromagnetic field, such as the squeezed state. In the first part we briefly describe: the standard results by Frank and Tamm for the Cerenkov effect based on the principles of classical electrodynamics; Fermi's results based on the radiative attenuation of the charged particle; the results of quantum-mechanical calculations. The quantum approach gives an important conclusion on the essence of the Cerenkov effect: in contrast to the classical approach, where the Cerenkov effect explains as a result of interaction of the charged particle with a medium, in the quantum case this effect can be explained as the result of interaction of the charged particle with the electromagnetic vacuum changed by a medium. Within the quantum approach, we obtained also the explicit analytic expression for the Cerenkov radiation in the case when an electron moves in the background of the squeezed state of electromagnetic vacuum (only quantum approach can be applied in this case due to a non-classical essence of the squeezed electromagnetic vacuum). Also, we obtained the explicit analytic expression for the Cerenkov radiation in an external laser field. In this case, the Cerenkov radiation can be interpreted as a stimulated process in contrast to the “classical” case, where the Cerenkov radiation has a spontaneous essence.
- Published
- 2019
- Full Text
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19. Managing Knowledge Integration across Boundaries FredrickTell, ChristianBerggren, StefanoBrusoni, and AndrewVan de Ven (eds) Oxford University Press, 2017, 305 pp., £55. ISBN: 9780198785972
- Author
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Hang T. T. Nguyen
- Subjects
021103 operations research ,Knowledge integration ,0502 economics and business ,05 social sciences ,Industrial relations ,Ven ,0211 other engineering and technologies ,02 engineering and technology ,Sociology ,Humanities ,050203 business & management - Published
- 2017
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20. Crohn’s Disease-Associated Adherent-Invasive Escherichia coli Manipulate Host Autophagy by Impairing SUMOylation
- Author
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Sébastien Massier, Richard Bonnet, Julien Delmas, Guillaume Dalmasso, Tiphanie Faïs, Nicolas Barnich, Hang T T Nguyen, Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne), CHU Clermont-Ferrand, Ministere de la Recherche et de la Technologie European Union FP7 People Marie Curie International Incoming Fellowship 'Region Auvergne' ('Nouveau Chercheur' grants) Inserm (U1071) INRA (USC-2018), Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte - Clermont Auvergne (M2iSH), Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne (UCA)-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne), and CHU Gabriel Montpied (CHU)
- Subjects
0301 basic medicine ,Genetically modified mouse ,Crohn’s disease ,autophagy ,SUMO protein ,Inflammation ,Mice, Transgenic ,Biology ,medicine.disease_cause ,Bacterial Adhesion ,Article ,03 medical and health sciences ,Mice ,0302 clinical medicine ,Intestinal mucosa ,Crohn Disease ,Cell Line, Tumor ,medicine ,Escherichia coli ,post-translational modifications ,Animals ,Humans ,Intestinal Mucosa ,Receptor ,lcsh:QH301-705.5 ,Escherichia coli Infections ,Autophagy ,Sumoylation ,[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology ,General Medicine ,Protein Inhibitors of Activated STAT ,[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology ,Cell biology ,030104 developmental biology ,lcsh:Biology (General) ,SUMO ,030220 oncology & carcinogenesis ,Ubiquitin-Conjugating Enzymes ,medicine.symptom ,Intracellular ,AIEC - Abstract
International audience; The intestinal mucosa of Crohn's disease (CD) patients is abnormally colonized with adherent-invasive Escherichia coli (AIEC) that are able to adhere to and to invade intestinal epithelial cells (IECs), to survive in macrophages, and to induce a pro-inflammatory response. AIEC persist in the intestine, and induce inflammation in CEABAC10 transgenic mice expressing human CAECAM6, the receptor for AIEC. SUMOylation is a eukaryotic-reversible post-translational modification, in which SUMO, an ubiquitin-like polypeptide, is covalently linked to target proteins. Here, we investigated the role of SUMOylation in host responses to AIEC infection. We found that infection with the AIEC LF82 reference strain markedly decreased the levels of SUMO-conjugated proteins in human intestinal epithelial T84 cells. This was also observed in IECs from LF82-infected CEABAC10 transgenic mice. LF82-induced deSUMOylation in IECs was due in part to increased level of microRNA (miR)-18, which targets PIAS3 mRNA encoding a protein involved in SUMOylation. Over-expression of SUMOs in T84 cells induced autophagy, leading to a significant decrease in the number of intracellular LF82. Consistently, a decreased expression of UBC9, a protein necessary for SUMOylation, was accompanied with a decrease of LF82-induced autophagy, increasing bacterial intracellular proliferation and inflammation. Finally, the inhibition of miR-18 significantly decreased the number of intracellular LF82. In conclusion, our results suggest that AIEC inhibits the autophagy response to replicate intracellularly by manipulating host SUMOylation.
- Published
- 2019
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21. States tomography of quantum systems via twisted light
- Author
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Peter A. Meleshenko, Olesya I. Kanishcheva, Vladimir A. Gorlov, Mikhail E. Semenov, Hang T. T. Nguyen, Alexander F. Klinskikh, and Svetlana A. Sokolova
- Subjects
Physics ,Density matrix ,Classical mechanics ,Electromagnetics ,Quantum state ,Lindblad equation ,Quantum system ,Quantum ,Quantum computer ,Gaussian beam - Abstract
Tomography of quantum state is an experimental procedure for determination of an unknown density operator ρ (the so called density matrix) which characterizes this state. In the case of single-qubit quantum system it is necessary to define the 12 parameters. While for the two-qubit system we should be assessed 240 parameters. Nevertheless, there are experimental techniques that allow to make a state's tomography. When the unitary evolution takes place we can use the von Neumann equation in formalism of quantum transformations, and when the non-unitary evolution takes place we can use the so-called Lindblad equation. Using a Gaussian beam (or twisted light) gives additional possibilities for realization of a quantum state's tomography procedure for different systems.
- Published
- 2017
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22. Radiation and control of coupled charged inverted pendulums
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Olga O. Reshetova, Hang T. T. Nguyen, Zainib Hatif Abbas, Andrey M. Solovyov, Mikhail E. Semenov, Mikhail A. Popov, Igor N. Ischuk, Peter A. Meleshenko, Vladimir A. Gorlov, and Alexander F. Klinskikh
- Subjects
Physics ,Mechanical system ,Work (thermodynamics) ,Classical mechanics ,Spring (device) ,Electric field ,medicine ,Stiffness ,Observable ,Radiation ,medicine.symptom ,Electromagnetic radiation - Abstract
In this work we consider the problem of a charged coupled (by a spring with stiffness k) inverted pendulums that are controlled by an external affection applied to the moving platform (such an affection is treated as a control). We consider the case of mechanical control as well as the possibility to use the control by an external electric field (due to the fact that the considered pendulums are charged). We also discuss some possible opportunities for control of unstable system based on the observable characteristics (e.g., the electromagnetic radiation from such a system).
- Published
- 2017
- Full Text
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23. Charged inverted pendulum as a new model for control of unstable systems
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Alexander F. Klinskikh, Peter A. Meleshenko, Vladimir A. Gorlov, Anton G. Rukavitcyn, Hang T. T. Nguyen, Zainib Hatif Abbas, Mikhail E. Semenov, and Olga O. Reshetova
- Subjects
Physics ,Electromagnetics ,Adaptive control ,Automatic control ,Computer simulation ,Observable ,01 natural sciences ,Inverted pendulum ,Classical mechanics ,Control theory ,Control system ,0103 physical sciences ,010306 general physics ,010301 acoustics - Abstract
In this work we investigate the model of charged inverted pendulum together with the problem of control for such a system. The control is based on the state-feedback principles. The considered system opens a new way for control of unstable systems using the external physical fields (in particular, electric field). We have also present the way for adaptive control of the system under consideration. The results of numerical simulations are presented and discussed. We also discuss some possible opportunities for control of unstable system based on the observable characteristics (electromagnetic radiation).
- Published
- 2016
- Full Text
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24. Fresh look at Lorenz-like system
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Alexander F. Klinskikh, Peter A. Meleshenko, Ilya E. Kuznetsov, Hang T. T. Nguyen, Vladimir A. Gorlov, and Mikhail E. Semenov
- Subjects
Nonlinear Sciences::Chaotic Dynamics ,Physics ,Electromagnetics ,Classical mechanics ,Trajectory ,Acceleration (differential geometry) ,Atmospheric model ,System of linear equations ,Electromagnetic radiation ,Unobservable ,Charged particle - Abstract
In this paper we consider the charged particle which moves by a trajectory describing by the Lorenz-like system of equation. Of course, because of non-zero acceleration this particle can be considered as a source of electromagnetic radiation. Such a radiation allows to investigate the system under consideration in the case when the system as itself is unobservable. This fact allows to obtain an interesting result as well as to take a fresh look at the chaotic systems that describe by the Lorenz-like system of equations.
- Published
- 2016
- Full Text
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25. Spectroscopic peculiarities in a 2D Coulomb potential under Aharonov-Bohm effect
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Peter A. Meleshenko, Alexander F. Klinskikh, and Hang T. T. Nguyen
- Subjects
Physics ,Condensed matter physics ,Flux ,Observable ,Quantum Physics ,Electron ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,Atomic and Molecular Physics, and Optics ,Magnetic flux ,Spectral line ,symbols.namesake ,Bound state ,symbols ,Electric potential ,Aharonov–Bohm effect - Abstract
In this paper we demonstrate some spectroscopic peculiarities which occur in the presence of the Aharonov-Bohm effect. As an object of investigation the system of a two-dimensional (2D) Coulomb potential in the presence of the Aharonov-Bohm flux is considered. It is shown, that the bound states in such a system “feel” the presence of the magnetic flux. In particular, the numerical analysis shows that the oscillator strengths of optical transitions turn into zero at some “special” values of the Aharonov-Bohm flux. As a result, some spectral lines (namely, the intensities of spectral lines) will disappear and this fact may be considered as an observable optical manifestation of the Aharonov-Bohm effect in the considered system. The dynamic polarisability of the bound states of an electron in such a system is also analyzed. It is shown numerically that the dynamic polarisability “strongly” depends on the values of the Aharonov-Bohm flux.
- Published
- 2013
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