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Cases of mongolism in twins are rather rare. We have been able to find reports of only 59 such cases in the literature. They are of special interest in that they afford an opportunity, not otherwise available, of investigating certain phases of the etiology of that condition.In the course of a study of mental disorders in twins, undertaken over three years ago, we have collected records of 1,014 pairs of twins one or both of whom presented a mental disorder. The material is now being analyzed by clinical groups.In our collection are included records of 5 pairs of twins with mongolism. The object of this communication is twofold: first, to report our cases, and second, to utilize this and other material in a study of the etiology of mongolism. REPORT OF CASES Case 1.—Monozygotic female twins, both affected.The T. twins, Florence and Frances, were born in

Several years ago we undertook to collect material for a study of mental disorders in twins. A preliminary report of this study was read before the California Medical Association in 1931.1 In that report are given a general plan of the study and a tabulated summary of the findings in 127 pairs of twins with mental disorders which had been accumulated up to that time.Since then the work of collecting the material has been completed. We now have in our possession case records of 1,011 pairs of twins (including 8 sets of triplets) with mental disorders and a control group of 308 pairs of normal twins. This material is now being analyzed and prepared for publication. In the collection are included 107 pairs of twins with epilepsy. The object of this communication is twofold: first, to present an analysis of this group of cases, and second, to utilize

Only a few cases of Huntington's chorea in twins have been reported. Our search through the literature has brought to light reports of only four such cases. In the course of our study of mental disorders in twins a case of this kind was brought to our attention by Dr. George H. Stevenson, superintendent of the Ontario Hospital at Whitby, Canada.The object of this communication is to review briefly the reports of cases gathered from the literature and to report a new case. REPORT OF CASES CASE 1 (RUSSELL,1 1894). —Male twins, probably monozygotic, both affected.The father of the twins was choreic as was also probably the paternal grandmother. The twins had three brothers and three sisters (ages not given) who were free from chorea at the time of the report. The chorea developed in both twins at the age of 27 years, occurring a little earlier